CN206937137U - A kind of L-type hole position micro-fluidic chip leads to liquid fixture - Google Patents

A kind of L-type hole position micro-fluidic chip leads to liquid fixture Download PDF

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Publication number
CN206937137U
CN206937137U CN201720458222.7U CN201720458222U CN206937137U CN 206937137 U CN206937137 U CN 206937137U CN 201720458222 U CN201720458222 U CN 201720458222U CN 206937137 U CN206937137 U CN 206937137U
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CN
China
Prior art keywords
base
liquid
hole position
type hole
fluidic chip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201720458222.7U
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Chinese (zh)
Inventor
郭钟宁
吴玲海
张文斌
刘莉
陈玲玉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Foshan Gewei Technology Co Ltd
Guangdong University of Technology
Original Assignee
Foshan Gewei Technology Co Ltd
Guangdong University of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foshan Gewei Technology Co Ltd, Guangdong University of Technology filed Critical Foshan Gewei Technology Co Ltd
Priority to CN201720458222.7U priority Critical patent/CN206937137U/en
Application granted granted Critical
Publication of CN206937137U publication Critical patent/CN206937137U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a kind of L-type hole position micro-fluidic chip to lead to liquid fixture, including inlet clamp assembly, the inlet clamp assembly includes first base and the top board above the first base, the top board is provided with the logical liquid component coordinated with chip, the locating dowel for keeping parallelism degree is provided between the first base and the top board, the first base is provided with the supporting plate for being used for placing the chip, and the supporting plate is removably fixedly connected with the first base.Using logical liquid fixture disclosed in the utility model, the replacing for realizing supporting plate is removably fixedly connected with first base by supporting plate, it is convenient to be changed when different chips are carried out with logical liquid, it is and easy to operate succinct, with versatility, and it is spacing to the depth of parallelism progress between first base and top board by locating dowel, to ensure the parallel of the two, stressed uniformity is applied in raising.

Description

A kind of L-type hole position micro-fluidic chip leads to liquid fixture
Technical field
Chemical industry processing equipment field is the utility model is related to, is led to more specifically to a kind of L-type hole position micro-fluidic chip Liquid fixture.
Background technology
In recent years, micro-fluidic chip has obtained significant progress in medical treatment, chemical industry, life science, environment measuring etc.. It manufactures material and is also transferred to the macromolecules such as PDMS, PMMA, COC, PP, PC by inorganic materials such as initial monocrystalline silicon, glass Polymer, on the one hand reduces manufacturing cost, on the other hand expands the use range of micro-fluidic chip.
In polymeric micro-fluidic chip, PDMS is elastomeric material, and its logical liquid mode is also relatively simple, directly by capillary The liquid in-out mouth of chip is inserted, then with silica gel sealing, you can logical liquid is tested.Stiff polymer material, as PMMA, COC, The micro-fluidic chip of the manufactures such as PP, PC is, it is necessary to which supporting liquid fixture logical accordingly carries out logical liquid experiment.
Existing corresponding product can solve the problems, such as the logical liquid of hard material micro-fluidic chip in the market, but general Property is poor, it is also difficult to adapts to the logical liquid requirement of more money chips.
In summary, how to efficiently solve that micro-fluidic chip clamp versatility is poor, can not meet that various chips lead to liquid It is required that the problems such as, it is current those skilled in the art's urgent problem.
Utility model content
In view of this, the purpose of this utility model is that providing a kind of L-type hole position micro-fluidic chip leads to liquid fixture, to solve The problems such as micro-fluidic chip clamp versatility is poor, the logical liquid requirement that can not meet various chips.
In order to achieve the above object, the utility model provides following technical scheme:
A kind of L-type hole position micro-fluidic chip leads to liquid fixture, including inlet clamp assembly, the inlet clamp assembly bag First base and the top board above the first base are included, the top board is provided with the logical liquid component coordinated with chip, The locating dowel for keeping parallelism degree is provided between the first base and the top board, the first base, which is provided with, to be used to put The supporting plate of the chip is put, the supporting plate is removably fixedly connected with the first base.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, set between the first base and the top board There is housing screw, the back-moving spring for reset is set with outside the housing screw.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, the first base is provided with neck, described Supporting plate is removably fixedly connected through the neck with the first base.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, the top board is provided with multiple for placing institute State the screwed hole of logical liquid component.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, in addition to liquid outlet clamp assembly, it is described go out Liquid mouth clamp assembly includes second base, and the second base is provided with guide rod and the stopper slot for placing the chip, institute The sliding clamp that perpendicular setting is arranged with guide rod is stated, the sliding clamp is provided with the liquid outlet being used for the chip The logical liquid component coordinated, the sliding clamp are removably fixedly connected with the second base through compressing member.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, the compressing member includes clinching and pull bar, institute State second base and be provided with and be used for the chute that the pull bar slides, the clinching is connected with the sliding clamp through being screwed.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, the second base, which is provided with, to be used to install institute The installing plate of guide rod is stated, the installing plate is threadedly coupled with the second base.
Preferably, lead in above-mentioned L-type hole position micro-fluidic chip in liquid fixture, the number of the sliding clamp is two.
L-type hole position micro-fluidic chip provided by the utility model leads to liquid fixture, including inlet clamp assembly, inlet folder Tool component includes first base and the top board above first base, and top board is provided with the logical liquid component coordinated with chip, The locating dowel for keeping parallelism degree is provided between first base and top board, first base is provided with the support for chip placement Plate, supporting plate are removably fixedly connected with first base.Using logical liquid fixture provided by the utility model, pass through supporting plate and first Base is removably fixedly connected with the replacing for realizing supporting plate, and it is convenient and easy to operate to be changed when different chips are carried out with logical liquid Succinctly, there is versatility, and it is spacing to the depth of parallelism progress between first base and top board by locating dowel, to ensure the two It is parallel, raising apply stressed uniformity.
Brief description of the drawings
, below will be to embodiment in order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art Or the required accompanying drawing used is briefly described in description of the prior art, it should be apparent that, drawings in the following description are only It is some embodiments of the utility model, for those of ordinary skill in the art, is not paying the premise of creative work Under, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the inlet clamp assembly that the L-type hole position micro-fluidic chip that the utility model embodiment provides leads to liquid fixture Main structure diagram;
Fig. 2 is Fig. 1 overlooking the structure diagram;
Fig. 3 is Fig. 1 side structure schematic view;
Fig. 4 is the liquid outlet clamp assembly that the L-type hole position micro-fluidic chip that the utility model embodiment provides leads to liquid fixture Main structure diagram;
Fig. 5 is Fig. 4 overlooking the structure diagram;
Fig. 6 is the surface structure schematic diagram that the L-type hole position micro-fluidic chip that the utility model embodiment provides leads to liquid fixture.
Marked in accompanying drawing as follows:
First base 1, back-moving spring 2, top board 3, milled screw 4, chip 5, logical liquid component 6, supporting plate 7, locating dowel 8, Second base 9, clinching 10, sliding clamp 11, pull bar 12, guide rod 13.
Embodiment
The utility model embodiment discloses a kind of L-type hole position micro-fluidic chip and leads to liquid fixture, to solve micro-fluidic chip The problems such as fixture versatility is poor, the logical liquid requirement that can not meet various chips.
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the embodiment of the utility model is carried out Clearly and completely describing, it is clear that described embodiment is only the utility model part of the embodiment, rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made The every other embodiment obtained, belong to the scope of the utility model protection.
Fig. 1-Fig. 6 is referred to, Fig. 1 is that the L-type hole position micro-fluidic chip that the utility model embodiment provides leads to liquid fixture The main structure diagram of inlet clamp assembly;Fig. 2 is Fig. 1 overlooking the structure diagram;The side view structure that Fig. 3 is Fig. 1 is shown It is intended to;Fig. 4 is the master for the liquid outlet clamp assembly that the L-type hole position micro-fluidic chip that the utility model embodiment provides leads to liquid fixture Depending on structural representation;Fig. 5 is Fig. 4 overlooking the structure diagram;Fig. 6 is the L-type hole position miniflow that the utility model embodiment provides Control the surface structure schematic diagram that chip leads to liquid fixture.
In one embodiment, L-type hole position micro-fluidic chip 5 provided by the utility model leads to liquid fixture, including feed liquor Mouth clamp assembly, inlet clamp assembly includes first base 1 and the top board 3 above first base 1, top board 3 are set There is the logical liquid component 6 coordinated with chip 5, leading to liquid component 6 includes device, pressure head and the chips such as pressure head, PEEK adapters, capillary Seal washer is provided between 5, highly pressurised liquid is injected into the passage on chip 5 by capillary by high-pressure pump, realizes the logical liquid of chip 5 Process, the concrete form of logical liquid component 6 can be configured according to being actually needed, or with reference to prior art, its specific position And installation relation will not be repeated here.
The locating dowel 8 for keeping parallelism degree is provided between first base 1 and top board 3, locating dowel 8 is preferably alignment pin Nail, by parallel between both shop bolt realizations, stressed stability and uniformity are applied in raising, avoid sending out during feed liquor The raw phenomenon of leakage.First base 1 is provided with supporting plate 7, and supporting plate 7 can be made by 3D printing, and making is simple and convenient, and cost is low, smart Degree is high.Supporting plate 7 is removably fixedly connected with first base 1, can be timely to meet the logical liquid demand of different in width chip 5 Change, there is higher compatibility.Its specific fixed form can be configured according to being actually needed, of the present utility model In protection domain.
During specific logical liquid, supporting plate 7 is prevented in first base 1, in general, in first base 1 and upper pressure Compressing member is provided between plate 3, to be compressed to the two, by the keeping parallelism degree of locating dowel 8 between top board 3 and first base 1, Then chip 5 is fixed on predeterminated position, the axle of the inlet axis of chip 5 and the pressure head in the logical liquid component 6 of upper rock beam installation Line aligns, and can carry out logical liquid experiment, and in logical liquid, when leading to liquid, liquid injects chip 5, PEEK switchings by high-pressure pump through capillary Head plays capillary and seals the connection function between pressure head.Pressure head, which is connected through a screw thread, to be fixed on top board 3, can be according to core The different-thickness of piece 5 easily adjusts the gap between first base 1 and top board 3, preferably adjusts thrust.Seal washer It is fixed on pressure head, in course of exerting pressure, the sealing between pressure head and chip 5 is ensured by its generation deformation, prevents leakage.
Specifically, being provided with housing screw between first base 1 and top board 3, answering for reset is set with outside housing screw Position spring 2.
Housing screw can be specially milled screw 4, can be adjusted by tightening milled screw 4 according to the different-thickness of chip 5 The depth being threaded into, thrust is preferably adjusted, and after the completion of the experiment of logical liquid, unscrew milled screw 4, back-moving spring 2 makes Top board 3 and first base 1 depart from, you can take out chip 5, the liquid feeding end operation for leading to liquid experiment is completed.Certainly, implement at other In example, the compressing member of other forms can also be selected, as long as technique effect in the same manner can be reached, to concrete implementation shape Formula is not construed as limiting, in the scope of protection of the utility model.
Further, first base 1 is provided with neck, and supporting plate 7 is removably fixedly connected through neck with first base 1. Supporting plate 7 chip 5 is carried out provided with step it is spacing, when in the supporting plate 7 that chip 5 is pushed between top board 3 and first base 1 When, the step on supporting plate 7 carries out spacing and positioning to it.
Further, top board 3 is provided with multiple screwed holes for being used to place logical liquid component 6.In order to meet different in width The installation of chip 5 needs, and can be threaded hole in the corresponding position of top board 3 according to the inlet of different chips 5, with installation Logical liquid component 6 carries out logical liquid to different chips 5, and said apparatus can carry out logical liquid to different in width chip 5, have versatility.
On the basis of the various embodiments described above, in addition to liquid outlet clamp assembly, liquid outlet clamp assembly include the second bottom Seat 9, second base 9 is provided with guide rod 13 and the stopper slot for chip placement 5, and perpendicular setting is arranged with guide rod 13 Sliding clamp 11, sliding clamp 11 are provided with the logical liquid component 6 for being used for coordinating with the liquid outlet of chip 5, sliding clamp 11 and the Two bases 9 are removably fixedly connected through compressing member.
Liquid outlet clamp assembly includes second base 9, and second base 9 is provided with guide rod 13 and stopper slot, covered on guide rod 13 Provided with sliding clamp 11, sliding clamp 11 is slided on guide rod 13, and logical liquid component 6 is provided with sliding clamp 11 with to chip 5 Logical liquid is carried out, is removably fixedly connected through compressing member between sliding clamp 11 and second base 9, compressing member can be specially screw etc. Form, as long as technique effect in the same manner can be reached, concrete implementation form is not construed as limiting.
When in use, chip 5 is prevented in second base 9, by sliding clamp 11 by logical liquid component 6 and liquid outlet Axis is aligned, and positioning of the sliding clamp 11 in second base 9 is realized by compressing member, is completed after compressing operation, can be carried out Logical liquid experiment, the liquid of fluid hole are derived there, collected.Seal washer completes the sealing between chip 5 and pressure head, in chip 5 Liquid the container specified is imported into via the capillary being inserted in PEEK adapters.
The inlet opening fixture and fluid hole fixture of the device can be combined the logical liquid of realization according to the different models of chip 5, Therefore there is certain versatility;The inlet opening fixture and fluid hole fixture of chip 5 separately design, and are adapted to different products Length.Inlet opening clip end uses replaceable supporting plate 7, in that context it may be convenient to is changed, is realized to any wide according to the width of chip 5 The chip 5 of degree is quickly compatible, and easy to operate succinct, positioning precision is high.
Further, compressing member includes clinching 10 and pull bar 12, and second base 9, which is provided with, is used for the cunning that pull bar 12 slides Groove, clinching 10 are connected with sliding clamp 11 through being screwed.
In order to realize the fixation between sliding clamp 11 and second base 9, clinching 10, pull bar 12 are set on sliding clamp 11 Slip in second base 9 is realized by chute, and can be according to the screw thread screwed between clinching 10 and sliding clamp 11, to pull bar 12 regulation is adjusted, in that context it may be convenient to which control is applied to the pressure on sliding clamp 11, and clinching 10 is set according to eccentric center principle Meter, while ensureing to apply enough pressure, possess good self-locking performance, the pressure of application is balanced, stably, side simple to operate Just.Certainly, only preferred embodiment herein, in other embodiments, can also select the pressure of other forms as needed Tight device, as long as identical technique effect can be reached, concrete implementation form is not construed as limiting.
Further, second base 9 is provided with the installing plate for installation guide rod 13, installing plate and the spiral shell of second base 9 Line connects.
For the ease of installing and dismantling, installation of the guide rod 13 in second base 9 can be realized by installing plate, in general, Installing plate can be fixed in second base 9 by bolt or screw, certainly, in other embodiments, can also be as needed Voluntarily set, will not be repeated here.
Specifically, the number of sliding clamp 11 is two.The liquid outlet fixture can realize leading for two liquid outlet chips 5 Liquid, two pieces of sliding clamps 11 can free control room away to adapt to the chip 5 of different in width, it is to be understood that by above-mentioned Device can also realize the drain of a liquid outlet chip 5.
In one embodiment, the bottom plate of liquid outlet clamp assembly is supported to chip 5, and the step on bottom plate is to chip 5 progress are spacing, and sliding clamp 11 is coordinated with guide rod 13 by gap allows it to be slided on guide rod 13, the platform of sliding clamp 11 After rank contacts with chip 5, clinching 10 is pressed, completing can be by adjustment length to the spacing of chip 5 and positioning, pull bar 12, can be with The pressure that control sliding clamp 11 applies to chip 5.Liquid outlet clamp assembly uses the side that sliding clamp 11 is combined with guide rod 13 Formula is positioned and pressed.Liquid outlet clamp assembly is pressed using clinching 10, and the pressure of application is balanced, and self-locking performance is good, behaviour Make convenient and simple.
After inlet clamp assembly and liquid outlet clamp assembly are individually designed, the chip 5 of random length is adapted to. In the case that inlet opening relative position is similar with L-type hole position, inlet opening fixture is realized by using the mode of replaceable supporting plate 7 It is quickly compatible to the chip 5 of any width.Supporting plate 7 is manufactured using 3D printing technique, and manufacturing speed is fast, and precision is high, cheap. The hand at inlet clamp assembly end is twisted the force surface of milled screw 4 and designed on the same face with the median plane of feed liquor hole position, can To improve the stability and uniformity of the pressure applied, avoid producing gap between seal washer and chip 5, cause leakage.And Such a design can apply enough pressure in course of exerting pressure, enter horizontal high voltage and lead to liquid experiment.
The fixture of micro-fluidic chip 5 installation it is simple, easy to operate, can to micro-fluidic chip 5 promote the use of play it is very big Facilitation.The fixture can be used continuously after simple assembly work is completed without dismantling again.During use, only Want each parts of coordinated manipulation that logical liquid operation can be achieved.
Each embodiment is described by the way of progressive in this specification, what each embodiment stressed be and other The difference of embodiment, between each embodiment identical similar portion mutually referring to.
The foregoing description of the disclosed embodiments, professional and technical personnel in the field are enable to realize or new using this practicality Type.A variety of modifications to these embodiments will be apparent for those skilled in the art, determine herein The General Principle of justice can be realized in other embodiments in the case where not departing from spirit or scope of the present utility model.Cause This, the utility model is not intended to be limited to the embodiments shown herein, and is to fit to and principles disclosed herein The most wide scope consistent with features of novelty.

Claims (8)

1. a kind of L-type hole position micro-fluidic chip leads to liquid fixture, it is characterised in that including inlet clamp assembly, the inlet Clamp assembly includes first base and the top board above the first base, and the top board is provided with what is coordinated with chip Logical liquid component, is provided with the locating dowel for keeping parallelism degree between the first base and the top board, in the first base Provided with the supporting plate for placing the chip, the supporting plate is removably fixedly connected with the first base.
2. L-type hole position micro-fluidic chip according to claim 1 leads to liquid fixture, it is characterised in that the first base and Housing screw is provided between the top board, the back-moving spring for reset is set with outside the housing screw.
3. L-type hole position micro-fluidic chip according to claim 2 leads to liquid fixture, it is characterised in that in the first base Provided with neck, the supporting plate is removably fixedly connected through the neck with the first base.
4. L-type hole position micro-fluidic chip according to claim 3 leads to liquid fixture, it is characterised in that the top board is provided with Multiple screwed holes for being used to place the logical liquid component.
5. the L-type hole position micro-fluidic chip according to claim any one of 1-4 leads to liquid fixture, it is characterised in that also includes Liquid outlet clamp assembly, the liquid outlet clamp assembly include second base, and the second base is provided with guide rod and for putting The stopper slot of the chip is put, the sliding clamp of perpendicular setting is arranged with the guide rod, the sliding clamp is provided with For the logical liquid component with the cooperation of the liquid outlet of the chip, the sliding clamp can through compressing member with the second base Dismounting is fixedly connected.
6. L-type hole position micro-fluidic chip according to claim 5 leads to liquid fixture, it is characterised in that the compressing member includes Clinching and pull bar, the second base, which is provided with, is used for the chute that the pull bar slides, and the clinching passes through with the sliding clamp Be screwed connection.
7. L-type hole position micro-fluidic chip according to claim 6 leads to liquid fixture, it is characterised in that in the second base Provided with the installing plate for installing the guide rod, the installing plate is threadedly coupled with the second base.
8. L-type hole position micro-fluidic chip according to claim 7 leads to liquid fixture, it is characterised in that the sliding clamp Number is two.
CN201720458222.7U 2017-04-26 2017-04-26 A kind of L-type hole position micro-fluidic chip leads to liquid fixture Expired - Fee Related CN206937137U (en)

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CN201720458222.7U CN206937137U (en) 2017-04-26 2017-04-26 A kind of L-type hole position micro-fluidic chip leads to liquid fixture

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108704681A (en) * 2018-05-25 2018-10-26 辽宁工业大学 A kind of instant-plugging micro-fluidic chip securing device
CN109449176A (en) * 2018-12-19 2019-03-08 积高电子(无锡)有限公司 Applied to cmos image sensor ceramics PGA adjustable sealing clamps
CN109939755A (en) * 2019-05-22 2019-06-28 上海邦先医疗科技有限公司 A kind of multichannel tandem micro-fluidic chip clamp system
CN110404603A (en) * 2019-08-28 2019-11-05 清华大学 A kind of stationary fixture of micro-fluidic chip
CN112774744A (en) * 2020-12-15 2021-05-11 扬州大学 Micro-fluidic device for multi-target quantitative detection
CN114453044A (en) * 2022-02-24 2022-05-10 中国科学院苏州生物医学工程技术研究所 Micro-fluidic chip clamping device

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108704681A (en) * 2018-05-25 2018-10-26 辽宁工业大学 A kind of instant-plugging micro-fluidic chip securing device
CN109449176A (en) * 2018-12-19 2019-03-08 积高电子(无锡)有限公司 Applied to cmos image sensor ceramics PGA adjustable sealing clamps
CN109939755A (en) * 2019-05-22 2019-06-28 上海邦先医疗科技有限公司 A kind of multichannel tandem micro-fluidic chip clamp system
CN109939755B (en) * 2019-05-22 2019-08-09 上海邦先医疗科技有限公司 A kind of multichannel tandem micro-fluidic chip clamp system
CN110404603A (en) * 2019-08-28 2019-11-05 清华大学 A kind of stationary fixture of micro-fluidic chip
US11857977B2 (en) 2019-08-28 2024-01-02 Tsinghua University Fixing clamp for microfluidic chip
CN112774744A (en) * 2020-12-15 2021-05-11 扬州大学 Micro-fluidic device for multi-target quantitative detection
CN112774744B (en) * 2020-12-15 2022-01-11 扬州大学 Micro-fluidic device for multi-target quantitative detection
CN114453044A (en) * 2022-02-24 2022-05-10 中国科学院苏州生物医学工程技术研究所 Micro-fluidic chip clamping device
CN114453044B (en) * 2022-02-24 2023-08-22 中国科学院苏州生物医学工程技术研究所 Micro-fluidic chip clamping device

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