CN206921488U - A kind of steerable optical tweezer model - Google Patents
A kind of steerable optical tweezer model Download PDFInfo
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- CN206921488U CN206921488U CN201720527987.1U CN201720527987U CN206921488U CN 206921488 U CN206921488 U CN 206921488U CN 201720527987 U CN201720527987 U CN 201720527987U CN 206921488 U CN206921488 U CN 206921488U
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- optical tweezer
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- steerable optical
- plane
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Abstract
A kind of steerable optical tweezer model, including at least three drive rods and a body, the drive rod is respectively provided at the both sides and rear end of the body, the front end of the body is provided with the manoeuvre portion for being used for manipulating particulate, during use, three-dimensional gradient ligh trap is formed using light forceps device, act on one or more drive rod of the steerable optical tweezer model, drive manoeuvre portion movement, particulate is manipulated, the steerable optical tweezer model structure is simple, material is easy to get, the control action of particulate is carried out indirectly by holographic light forceps device, it is not required to worry phototoxis particulate, new thinking is proposed for the application of optical tweezer technology, solves the limitation of light forceps device in the prior art indirectly.
Description
Technical field
It the utility model is related to optical tweezer field, more particularly to a kind of steerable optical tweezer model.
Background technology
According to maxwell theory, light itself, not only with energy, while also carries momentum in transmitting procedure.Now
Widely used micro element optical drive technology mainly utilizes the momentum of light, and typical example is optical tweezer, utilizes the light beam of strong-focusing
The strong laser field of near focal point captures, operated the device of small items.
Optical tweezer technology is the three-dimensional gradient ligh trap that is formed using the mechanics effect of momentum transmission between light and material to manipulate
The technology of particulate.Because optical tweezer has unique operation principle, it can be used for the capture and manipulation of molecule, and can be with
Living beings are non-contactly controlled, so optical optical tweezers system is widely used in field of biology.
Existing optical tweezer technology application field, it is usually directly micro- to manipulate using light forceps device formation three-dimensional gradient ligh trap
Grain, light forceps device can be as needed, and three-dimensional gradient ligh trap is adjusted, and is a kind of conveniently device.But this light
Forceps device has limitation：When the particulate is living beings such as cell, fuel factor can be produced in manipulation process, certain
Damaging cells in degree, it is therefore desirable to which, in view of influence of the light to particulate, intensity, type to light etc. all require, and this is to light
Forceps device proposes harsh requirement；Moreover, then it is difficult direct such as nerve cell if the particulate form is irregular
Manipulated using three-dimensional gradient ligh trap.
The limitation of light forceps device, development to optical tweezer technology, using proposing new test.
Utility model content
The purpose of this utility model is to provide a kind of steerable optical tweezer model, passes through light forceps device and manipulates optical tweezer mould
Type, then by optical tweezer model manipulation particulate, solve the limitation of light forceps device in the prior art indirectly.
What the utility model was realized in：A kind of steerable optical tweezer model, including at least three drive rods and one
Body, the drive rod are respectively provided at the both sides and rear end of the body, and the front end of the body, which is provided with, to be used to manipulate particulate
Manoeuvre portion.
In use, forming three-dimensional gradient ligh trap using light forceps device, one of the steerable optical tweezer model is acted on
Or on multiple drive rods, because light has momentum, therefore under the driving of light forceps device position can occur for the drive rod
Change, manoeuvre portion movement is driven, particulate is manipulated.
Using this technical scheme, the drive rod being arranged in three orientation of body, be advantageous to carry out stress when manipulating
Analysis, also makes the steerable optical tweezer model be not easy to turn on one's side；This steerable optical tweezer model structure is simple, is not easy side
Turn over, make use of light forceps device of the prior art to manipulate particulate indirectly, avoid light to living beings such as cell
Infringement.
As further improvement of the utility model, the drive rod includes stock and spheroid, and the spheroid passes through described
Stock is connected with the body, and the spheroid includes Other substrate materials.
Photoresist refers to that a major class has photosensitizing chemical effect（It is or sensitive to electron energy）Macromolecule polymer material；
Resist is called, is also photoresist, English name resist.Using spheroid made of Other substrate materials, it is quicker to light
Sense, can make light forceps device be easier to navigate to spheroid up, by driving spheroid, realize the behaviour to steerable optical tweezer model
It is vertical, spheroid is arranged to, the purpose is to not only for being moved easily, and in order to increase the contact area of light, improves and manipulates effect
Rate.
As further improvement of the utility model, the manoeuvre portion includes plane or cambered surface.People can be according to not
With the shape of particulate, different manoeuvre portions is selected.
As further improvement of the utility model, the drive rod is three, and the body is cuboid, the body
Length and it is high form the first plane, the second plane respectively, the 3rd plane of wide and high formation respectively, the fourth plane of the body,
Three drive rods are separately positioned in the first plane, the second plane and the 3rd plane, and the manoeuvre portion is located at fourth plane
On.Using this technical scheme, drive rod quantity is few, easily makes, and stress is symmetrical, easily manipulates.
As further improvement of the utility model, a length of 40-60 μm of the body, a width of 10-30 μm, a height of 10-
20μm.Using this technical scheme, suitable for most cell, the capture of particulate, manipulation work.
As further improvement of the utility model, the radius of the spheroid is 5-10 μm, and one end of the stock is embedded in
To the inside of the spheroid.Using this technical scheme, suitable for the manipulation work of most particulate.
As further improvement of the utility model, the spheroid is made up of SU-8 photoresists.Using this technical scheme,
The function admirable of SU-8 photoresists, cheap and easy to get, cost is low.
As further improvement of the utility model, the steerable optical tweezer model is made up of SU-8 photoresists.
The steerable optical tweezer model is manipulated by holographic light forceps device, and its manipulation process includes the holographic optical
Forceps device transmitting Gauss light is acted on the spheroid of the steerable optical tweezer model, moves the steerable optical tweezer model
It is dynamic.
Gauss light refers under usual situation that the basic mode radiation field that laserresonator is sent, the distribution of amplitudes of its cross section is abided by
Keep the light of Gaussian function.Gauss light is a kind of light widely used in optical tweezer field.Holographic light forceps device is to utilize holography
The light forceps device of the light field with specific function of element structure, its use is wide, can complete such as the rotating of single-particle, more
The functions such as the manipulation and sorting of particle.
Steerable optical tweezer model is manipulated using above-mentioned technical scheme, manoeuvrable, meets different uses
The requirement of different control actions of the person to particulate.
Compared with prior art, the beneficial effects of the utility model are：The steerable optical tweezer model uses conventional light
Spheroid is made in photoresist material, and simple in construction, material is easy to get, and the control action of particulate is carried out indirectly by holographic light forceps device,
It is not required to worry phototoxis particulate, proposes new thinking for the application of optical tweezer technology, solve light in the prior art indirectly
The limitation of forceps device.
Brief description of the drawings
Fig. 1 is a kind of steerable optical tweezer model structure schematic diagram.
Fig. 2 is a kind of top view of steerable optical tweezer model.
Fig. 3 is a kind of front view of steerable optical tweezer model.
Fig. 4 is a kind of side view of steerable optical tweezer model.
Fig. 5 is a kind of embodiment schematic diagram of steerable optical tweezer model.
Brief description of the drawings：1- drive rods, 101- stocks, 102- spheroids, 2- bodies, the planes of 21- first, the planes of 22- second,
The planes of 23- the 3rd, 24- fourth planes, 3- manoeuvre portions, 4- lasers, 5- beam expanders, 6- lens, 7- spatial light modulators, 8- are anti-
Penetrate mirror, 9- spectroscopes, 10- object lens, 11- ccd image sensors, 12- computers, 13- illuminating lamps, the steerable optical tweezers of 100-
Model.
Embodiment
In order to illustrate more clearly of the embodiment of the present application or technical scheme of the prior art, below in conjunction with the accompanying drawings and specifically
Embodiment further illustrates to the utility model.
Embodiment 1
A kind of steerable optical tweezer model as Figure 1-4, including at least three drive rods 1 and a body 2, it is described
Drive rod 1 is respectively provided at the both sides and rear end of the body 2, and the front end of the body 2 is provided with the behaviour for being used for capturing, manipulate particulate
Vertical portion 3.
In use, forming three-dimensional gradient ligh trap using light forceps device, one of the steerable optical tweezer model is acted on
Or on multiple drive rods 1, because light has momentum, therefore under the driving of light forceps device position can occur for the drive rod 1
Change is put, drives manoeuvre portion 3 to move, particulate is manipulated.
Using this technical scheme, the drive rod 1 being arranged in three orientation of body, be advantageous to carry out stress when manipulating
Analysis, also makes the steerable optical tweezer model be not easy to turn on one's side；This steerable optical tweezer model structure is simple, is not easy side
Turn over, particulate is manipulated using light forceps device of the prior art indirectly, avoid light to living beings such as cell
Infringement.
Embodiment 2
On the basis of embodiment 1, as shown in Fig. 2 the drive rod 1 includes stock 101 and spheroid 102, the spheroid
102 are connected by the stock 101 with the body 2, and the spheroid 102 includes Other substrate materials.
Photoresist refers to that a major class has photosensitizing chemical effect（It is or sensitive to electron energy）Macromolecule polymer material；
Resist is called, is also photoresist, English name resist.Using spheroid 102 made of Other substrate materials, its to light more
Sensitivity, light forceps device can be made to be easier to navigate to spheroid 102 up, by driving spheroid 102, realized to steerable optical tweezer mould
The manipulation of type, spheroid 102 is arranged to, the purpose is to not only for being moved easily, and in order to increase the contact area of light, carried
High driving efficiency.
Embodiment 3
Further, the manoeuvre portion 3 includes plane or cambered surface.People can select according to the shape of different particulates
Different manoeuvre portions 3, by that analogy, the surface of manoeuvre portion 3 can also be made as to mat surface, or increase in manoeuvre portion 3
Clamping jaw or bar fork.For example, when nerve cell of the cell for fine length, number can be set on the surface of the manoeuvre portion 3
Individual bar fork, for catching on nerve cell.
Embodiment 4
Further, the drive rod 1 is three, and the body 2 is cuboid, the length of the body 2 and high shape respectively
Into the first plane 21, the second plane 22, the 3rd plane 23 of wide and high formation respectively, the fourth plane 24 of the body 2, described three
Individual drive rod 1 is separately positioned in the first plane 21, the second plane 22 and the 3rd plane 23, and the manoeuvre portion 3 is located at Siping City
On face 24.
The steerable optical tweezer model being fabricated to using embodiment 4, the quantity of drive rod 1 is few, easily makes, and stress is symmetrical,
Easily manipulate, good checking has been obtained in the practical operation in laboratory.
Further, a length of 40-60 μm of the body 2, a width of 10-30 μm, a height of 10-20 μm, the spheroid 102
Radius is 5-10 μm, and one end of the stock 101 is embedded into the inside of the spheroid 102.
Using the technical scheme of embodiment 4, suitable for most cell, the capture of particulate, manipulation work.
Embodiment 5
On the basis of embodiment 4, a length of 48 μm of the body 2, a width of 20 μm, a height of 14 μm, the spheroid 102
Radius is 7.5 μm, and one end of the stock 101 is embedded into the inside of the spheroid 102, and the center of the spheroid 102 is described in
The vertical range of body 2 is 20 μm.Using this embodiment, the steerable optical tweezer model movement is flexible, easily manipulates.
Embodiment 6
Further, the spheroid 102 is made up of SU-8 photoresists.Using this technical scheme, the performance of SU-8 photoresists
Excellent, cheap and easy to get, cost is low.
Further, the steerable optical tweezer model is made up of SU-8 photoresists.
Embodiment 7
The steerable optical tweezer model is manipulated by holographic light forceps device, and the holographic light forceps device utilizes Gauss
Light is manipulated.
Holographic light forceps device is under the auxiliary of computer, it is possible to achieve the hologram of arbitrary shape.With computer speed
Continuous refreshing and new algorithm appearance, can be easily achieved the complete of arbitrary shape in general R＆D units
Cease optical tweezer.Holographic optical tweezer can produce arbitrary shape, size, the ligh trap of quantity in principle.By the phase point for changing capture light
Cloth, line-of-road movement of the trapped particle by setting in ligh trap can be made, be a kind of very easily light forceps device.
A kind of holographic light forceps device for being used to manipulate the steerable optical tweezer model, as shown in figure 5, it includes laser
4th, 5, three lens 6 of beam expander, spatial light modulator 7, speculum 8, spectroscope 9, object lens 10, ccd image sensor 11, calculating
Machine 12 and illuminating lamp 13.
Wherein, the effect of the laser is transmitting laser, and the effect of the beam expander 5 is that the size of laser is adjusted
Section；The effect of the lens 6 is that light is focused；The effect of the spatial light modulator 7 is together with computer program
The parameters such as phase and the mode of laser are modulated, such as linear light is modulated into Gauss light, or light beam is modulated into multi-beam.
The effect of the spectroscope 9 is can to pass through part light, and and can part light reflects away.The object lens 10 are existing
The effect focused on to incident light, plays a part of zooming into picture again.Ccd image sensor 11 is used for the effect that observation model manipulates
Fruit, design sketch is fed back on computer 12.The computer 12 is used to run computer program to operate the holographic optical tweezer
Device.
The present embodiment provides a kind of application method of the steerable optical tweezer model, as shown in figure 5, first can by described in
The optical tweezer model 100 of manipulation is placed between object lens 10 and illuminating lamp 13, launches linear light from laser 4, linear light, which is injected, to expand
The size of linear light is adjusted for beam device 5, beam expander 5, and the linear light after regulation focuses on through lens 6, into space light modulation
Linear light after regulation is modulated to Gauss light by device 7, spatial light modulator 7, and the Gauss light injects speculum 8, by reflection
Spectroscope 9 is injected through two lens 6 after the reflection of mirror 8, after spectroscope 9 reflexes to microscopical object lens 10, is acted on
The steerable optical tweezer model.In addition, the image of steerable optical tweezer model enters spectroscope 9 by object lens 10, through undue
Light microscopic 9 is transmitted into ccd image sensor 11, and the ccd image sensor 11 is used for the effect that observation model manipulates, and will effect
Fruit figure is fed back on computer 12.
Spheroid is made using conventional Other substrate materials in this steerable optical tweezer model, and simple in construction, material is easy to get,
Ground connection carries out the control action of particulate by holographic light forceps device, is not required to worry phototoxis particulate, is the application of optical tweezer technology
New thinking is proposed, the limitation for solving light forceps device in the prior art indirectly.
Preferred embodiment of the present utility model is the foregoing is only, it is all at this not to limit the utility model
All any modification, equivalent and improvement made within the spirit and principle of utility model etc., should be included in the utility model
Protection domain within.
Claims (8)
1. a kind of steerable optical tweezer model, it is characterised in that including at least three drive rods（1）With a body（2）, it is described
Drive rod（1）It is respectively provided at the body（2）Both sides and rear end, the body（2）Front end be provided be used for manipulate particulate
Manoeuvre portion（3）.
2. steerable optical tweezer model according to claim 1, it is characterised in that the drive rod（1）Including stock
（101）And spheroid（102）, the spheroid（102）Pass through the stock（101）With the body（2）Connection, the spheroid
（102）Including Other substrate materials.
3. steerable optical tweezer model according to claim 2, it is characterised in that the manoeuvre portion（3）Including plane or
Person's cambered surface.
4. steerable optical tweezer model according to claim 3, it is characterised in that the drive rod（1）It is described for three
Body（2）For cuboid, the body（2）Length and high form the first plane respectively（21）, the second plane（22）, the body
（2）It is wide and high respectively formed the 3rd plane（23）, fourth plane（24）, three drive rods（1）It is separately positioned on first
Plane（21）, the second plane（22）With the 3rd plane（23）On, the manoeuvre portion（3）It is located at fourth plane（24）On.
5. steerable optical tweezer model according to claim 4, it is characterised in that the body（2）A length of 40-60 μ
M, a width of 10-30 μm, a height of 10-20 μm.
6. steerable optical tweezer model according to claim 4, it is characterised in that the spheroid（102）Radius be 5-
10 μm, the stock（101）It is embedded into the spheroid（102）Inside.
7. steerable optical tweezer model according to claim 4, it is characterised in that the spheroid（102）By SU-8 photoetching
Glue is made.
8. steerable optical tweezer model according to claim 4, it is characterised in that the steerable optical tweezer model by
SU-8 photoresists are made.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201720527987.1U CN206921488U (en) | 2017-05-12 | 2017-05-12 | A kind of steerable optical tweezer model |
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| CN201720527987.1U CN206921488U (en) | 2017-05-12 | 2017-05-12 | A kind of steerable optical tweezer model |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107068230A (en) * | 2017-05-12 | 2017-08-18 | 深圳大学 | A kind of steerable optical tweezer model |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107068230A (en) * | 2017-05-12 | 2017-08-18 | 深圳大学 | A kind of steerable optical tweezer model |
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| CF01 | Termination of patent right due to non-payment of annual fee |
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