CN206642104U - A kind of synthesizer of 68Ga marks chemicals - Google Patents

A kind of synthesizer of 68Ga marks chemicals Download PDF

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Publication number
CN206642104U
CN206642104U CN201621246052.8U CN201621246052U CN206642104U CN 206642104 U CN206642104 U CN 206642104U CN 201621246052 U CN201621246052 U CN 201621246052U CN 206642104 U CN206642104 U CN 206642104U
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China
Prior art keywords
pipeline
posts
bottle
shunt conduit
generators
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CN201621246052.8U
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Chinese (zh)
Inventor
徐志红
朱健
桂媛
刘正亮
邵黎明
沈佳宇
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JIANGSU HUAYI TECHNOLOGY Co.,Ltd.
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Suzhou Jingbiao Image Technology Co Ltd
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Priority to CN201621246052.8U priority Critical patent/CN206642104U/en
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Abstract

The utility model discloses one kind68Ga marks the synthesizer of chemicals, including syringe, connection triple valve, the triple valve are also respectively connected with solution bottle and Ge Ga generators by pipeline below the syringe, and the solution bottle is connected with Ge Ga generators by pipeline and pipeline is provided with pipeline valve;SCX posts, the upper end of the SCX posts are connected by pipeline with the Ge Ga generators, and the lower end of the SCX posts is provided with shunt conduit, and the shunt conduit connects waste liquid bottle A and receiving flask respectively, and the receiving flask is provided with feed hopper;C18 posts, the upper end of the C18 posts is connected by pipeline with the receiving flask and pipeline is provided with drawing liquid pump, and the lower end of the C18 posts is provided with shunt conduit, and the shunt conduit connects waste liquid bottle B and product bottle respectively.The utility model Tilly is produced with the solution of cleaning, reduces the impurity that other chemical reagent may be brought;Cleaning step is added, the other impurities isotope reduced in generator has an impact to mark.

Description

It is a kind of68Ga marks the synthesizer of chemicals
Technical field
Core medicine synthesis field is the utility model is related to, more particularly to it is a kind of68Ga marks the synthesizer of chemicals.
Background technology
At present, all kinds of tumor diseases are increasing, had a strong impact on the living standard of people, and accurate diagnosis and positioning are swollen Treatment of the knurl to the later stage has very important meaning.Utilize68Some chemicalses are marked Ga, are swept using positive electron Retouch, it is possible to increase the diagnosis rate of disease.Conventional technique route is by EDTA solution pair68Ga is eluted to obtain EDTA complexings Thing.By the method that ion exchange or solution extract EDTA and68Ga is separated, and obtains ionic68Ga.It this method increase Operating time, reduce68Ga actual yield.
Utility model content
The utility model is intended to one of technical problem at least solving in correlation technique to a certain extent.Therefore, this reality It is to propose one kind with a new purpose68Ga marks the synthesizer of chemicals, can simply and easily utilize68Ga is marked to target chemical medicine, reacts, synthesized, and whole process efficiently facilitates.
According to the synthesizer of the utility model embodiment, including:Syringe, the syringe lower section connection triple valve, The triple valve is also respectively connected with solution bottle and Ge-Ga generators by pipeline, and solution bottle and the Ge-Ga generator passes through pipe Road connects and pipeline is provided with pipeline valve;SCX posts, the upper end of the SCX posts are connected by pipeline with the Ge-Ga generators, The lower end of the SCX posts is provided with shunt conduit, and shunt conduit one end connection waste liquid bottle A, other end connection receiving flask are described Receiving flask is provided with feed hopper;C18 posts, the upper end of the C18 posts is connected by pipeline with the receiving flask and pipeline is provided with Drawing liquid pump, the lower end of the C18 posts are provided with shunt conduit, shunt conduit one end connection waste liquid bottle B, other end connection product Bottle.
In some embodiments of the utility model, the shunt conduit is provided with two branch flow pipes, two branch Flow divider A and flow divider B are respectively equipped with flow tube road.
In some embodiments of the utility model, the feed hopper is provided with inlet valve.
In some embodiments of the utility model, band is equipped with the solution bottle, Ge-Ga generators and receiving flask and is inserted The rubber stopper in hole.
Compared with prior art, the utility model proposes one kind68Ga marks the synthesizer of chemicals, and advantage exists In:1) produced using the solution of cleaning, reduce the impurity that other chemical reagent may be brought;2) cleaning step is added, The other impurities isotope reduced in generator has an impact to mark.
Brief description of the drawings
Accompanying drawing is used for providing further understanding to of the present utility model, and a part for constitution instruction, with this practicality New embodiment is used to explain the utility model together, does not form to limitation of the present utility model.In the accompanying drawings:
Fig. 1 is one kind68The structural representation of the synthesizer of Ga mark chemicalses;
Fig. 2 is the structural representation of feed hopper;
Fig. 3 is the structural representation of shunt conduit;
In figure:1- syringes, 2- solution bottles, 3-Ge-Ga generators, 4-SCX posts, 5- waste liquid bottle A, 6- receiving flask, 7- enter Hopper, 701- inlet valves, 8- drawing liquid pumps, 9-C18 posts, 10- products bottle, 11- triple valves, 12- pipelines, 13- pipeline valves, 14- point Flow tube road, 1401- flow divider A, 1402- flow divider B, 1403- branch flow pipe, 15- waste liquid bottles B.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the embodiment of the utility model is carried out Clearly and completely describing, it is clear that described embodiment is only the utility model part of the embodiment, rather than whole Embodiment.
The example of the embodiment is shown in the drawings, wherein same or similar label represents identical or class from beginning to end As element or with same or like function element.The embodiments described below with reference to the accompanying drawings are exemplary, purport For explaining the utility model, and it is not intended that to limitation of the present utility model.
In description of the present utility model, it is to be understood that term " " center ", " longitudinal direction ", " transverse direction ", " length ", " width Degree ", " thickness ", " on ", " under ", "front", "rear", "left", "right", " vertical ", " level ", " top ", " bottom " " interior ", " outer ", " suitable The orientation or position relationship of the instruction such as hour hands ", " counterclockwise ", " axial direction ", " radial direction ", " circumference " are based on orientation shown in the drawings Or position relationship, be for only for ease of description the utility model and simplify and describe, rather than instruction or imply signified device or Element must have specific orientation, with specific azimuth configuration and operation, therefore it is not intended that to limit of the present utility model System.
In addition, term " first ", " second " are only used for describing purpose, and it is not intended that instruction or hint relative importance Or the implicit quantity for indicating indicated technical characteristic.Thus, define " first ", the feature of " second " can be expressed or Implicitly include one or more this feature.In description of the present utility model, " multiple " are meant that two or two More than, unless otherwise specifically defined.
In the utility model, unless otherwise clearly defined and limited, term " installation ", " connected ", " connection ", " Gu It is fixed " etc. term should be interpreted broadly, for example, it may be fixedly connected or be detachably connected, or integrally;Can be Mechanically connect or electrically connect;Can be joined directly together, can also be indirectly connected by intermediary, can be two The connection of element internal or the interaction relationship of two elements.For the ordinary skill in the art, can basis Concrete condition understands concrete meaning of the above-mentioned term in the utility model.
Reference picture 1-3, it is a kind of68The synthesizer of Ga mark chemicalses includes syringe 1, the lower section of syringe 1 connection three Port valve 11, triple valve 11 are also respectively connected with solution bottle 2 and Ge-Ga generators 3, solution bottle 2 and Ge-Ga generators by pipeline 12 3 are connected and pipeline is provided with pipeline valve 13 by pipeline 12.
The upper end of SCX posts 4 is connected by pipeline 12 with Ge-Ga generators 3, and the lower end of SCX posts 4 is provided with shunt conduit 14, The one end of shunt conduit 14 connection waste liquid bottle A 5, other end connection receiving flask 6, receiving flask 6 are provided with feed hopper 7, on feed hopper 7 Provided with inlet valve 701.
The upper end of C18 posts 9 is connected by pipeline 12 with receiving flask 6 and pipeline 12 is provided with drawing liquid pump 8, the lower end of C18 posts 9 Provided with shunt conduit 14, the one end of shunt conduit 14 connection waste liquid bottle B 15, other end connection product bottle 10.
Shunt conduit 14 is provided with two branch flow pipes 1403, and flow divider A is respectively equipped with two branch flow pipes 1403 1401 and flow divider B 1402.
The rubber stopper (figure middle position mark) with jack, rubber are equipped with solution bottle 2, Ge-Ga generators 3 and receiving flask 6 The effect of plug is that pipeline is inserted in the jack on rubber stopper in order that keeping sealing in bottle.
Hydrochloric acid is housed, opening conduits valve 13, by regulating three-way valve 11 by syringe 1 and solution bottle 2 in solution bottle 2 It is logical, syringe 1 is pushed, hydrochloric acid in solution bottle 2 is pressed into Ge-Ga generators 3;Pipeline valve 13 is closed, passes through regulating three-way valve 11 by syringe 1 and the UNICOM of Ge-Ga generators 3, syringe 1 is pushed, by containing in Ge-Ga generators 1368Ge and68Ga's In hydrochloric acid solution pressure people SCX posts 4.
Open the flow divider A 1401 in the shunt conduit 14 of the lower end of SCX posts 4 and close flow divider B 1402, toward SCX posts 4 The inside first adds water and cleaning agent, washes away impurity, and waste liquid enters waste liquid bottle A 5 by branch flow pipe 1403;Close under SCX posts 4 Flow divider A 1401 and opening flow divider B 1402 in the shunt conduit 14 at end, add auxiliary liquid toward the inside of SCX posts 4, obtain Contain68Ga solution enters receiving flask 6.
The inlet valve 701 on feed hopper 7 is opened, precursor substance is added into receiving flask 6.
Flow divider B 1402 and inlet valve 701 in the shunt conduit 14 of SCX posts lower end are closed, will be collected by drawing liquid pump 8 Solution in bottle 6 is pumped into C18 posts 9;Open the flow divider A 1401 in the shunt conduit 14 of the lower end of C18 posts 9 and close flow divider B 1402, waste liquid is flowed into waste liquid bottle B 15;The flow divider A 1401 and opening point closed in the shunt conduit 14 of the lower end of C18 posts 9 Valve B 1402 is flowed, adds ethanol and brine C18 posts toward C18 posts 9 are inner, target product will flow into product bottle 10.
In the utility model, unless otherwise clearly defined and limited, fisrt feature is "above" or "below" second feature Can be that the first and second features directly contact, or the first and second features pass through intermediary mediate contact.Moreover, first is special Sign second feature " on ", " top " and " above " can be fisrt feature directly over second feature or oblique upper, or only Represent that fisrt feature level height is higher than second feature.Fisrt feature second feature " under ", " lower section " and " below " can be with Be fisrt feature immediately below second feature or obliquely downward, or be merely representative of fisrt feature level height and be less than second feature.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or the spy for combining the embodiment or example description Point is contained at least one embodiment or example of the present utility model.In this manual, to the schematic table of above-mentioned term State and be not necessarily referring to identical embodiment or example.Moreover, specific features, structure, material or the feature of description can be Combined in an appropriate manner in any one or more embodiments or example.
It is described above, the only preferable embodiment of the utility model, but the scope of protection of the utility model is not This is confined to, any one skilled in the art is in the technical scope that the utility model discloses, according to this practicality New technical scheme and its utility model design are subject to equivalent substitution or change, should all cover in protection model of the present utility model Within enclosing.

Claims (4)

  1. It is 1. a kind of68Ga marks the synthesizer of chemicals, it is characterised in that including:
    Syringe, the syringe lower section connection triple valve, the triple valve are also respectively connected with solution bottle and Ge-Ga by pipeline Generator, the solution bottle is connected with Ge-Ga generators by pipeline and pipeline is provided with pipeline valve;
    SCX posts, the upper end of the SCX posts are connected by pipeline with the Ge-Ga generators, and the lower end of the SCX posts, which is provided with, to be divided Flow tube road, shunt conduit one end connection waste liquid bottle A, other end connection receiving flask, the receiving flask are provided with feed hopper;
    C18 posts, the upper end of the C18 posts is connected by pipeline with the receiving flask and pipeline is provided with drawing liquid pump, the C18 posts Lower end be provided with shunt conduit, shunt conduit one end connection waste liquid bottle B, other end connection product bottle.
  2. 2. one kind according to claim 168Ga marks the synthesizer of chemicals, it is characterised in that the isocon Road is provided with two branch flow pipes, and flow divider A and flow divider B are respectively equipped with two branch flow pipes.
  3. 3. one kind according to claim 168Ga marks the synthesizer of chemicals, it is characterised in that the feed hopper It is provided with inlet valve.
  4. 4. one kind according to claim 168Ga marks the synthesizer of chemicals, it is characterised in that the solution bottle, The rubber stopper with jack is equipped with Ge-Ga generators and receiving flask.
CN201621246052.8U 2016-11-14 2016-11-14 A kind of synthesizer of 68Ga marks chemicals Active CN206642104U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621246052.8U CN206642104U (en) 2016-11-14 2016-11-14 A kind of synthesizer of 68Ga marks chemicals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621246052.8U CN206642104U (en) 2016-11-14 2016-11-14 A kind of synthesizer of 68Ga marks chemicals

Publications (1)

Publication Number Publication Date
CN206642104U true CN206642104U (en) 2017-11-17

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Country Status (1)

Country Link
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126648A (en) * 2018-01-04 2018-06-08 江苏华益科技有限公司 The automatic conveying device and method of a kind of radiopharmaceutical
CN113019279A (en) * 2021-03-11 2021-06-25 山西医科大学第一医院 Automatic synthesis device for preparing radiopharmaceuticals and using method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126648A (en) * 2018-01-04 2018-06-08 江苏华益科技有限公司 The automatic conveying device and method of a kind of radiopharmaceutical
CN113019279A (en) * 2021-03-11 2021-06-25 山西医科大学第一医院 Automatic synthesis device for preparing radiopharmaceuticals and using method thereof

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Effective date of registration: 20200323

Address after: 215000 No.18 Fuyu Road, Haiyu Town, Changshu, Suzhou, Jiangsu Province (New Material Industrial Park)

Patentee after: JIANGSU HUAYI TECHNOLOGY Co.,Ltd.

Address before: 215522, Jiangsu, Suzhou, Changshou City Hai Yu town (New Materials Industry Park), Fu Yu Road, No. 9, 18

Patentee before: SUZHOU JINGBIAO IMAGE TECHNOLOGY Co.,Ltd.