CN206631607U - Liquid control valve door gear and its micro-fluidic chip for micro-fluidic chip - Google Patents
Liquid control valve door gear and its micro-fluidic chip for micro-fluidic chip Download PDFInfo
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- CN206631607U CN206631607U CN201720340435.XU CN201720340435U CN206631607U CN 206631607 U CN206631607 U CN 206631607U CN 201720340435 U CN201720340435 U CN 201720340435U CN 206631607 U CN206631607 U CN 206631607U
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Abstract
The utility model discloses a kind of liquid control valve door gear and its micro-fluidic chip for micro-fluidic chip, the valving includes being used to sense the testing agency whether fluid flows through valving installation site;The valving of normally open is in micro-fluidic chip, when the numerical tabular free flow body that testing agency is fed back flows through valving installation site, can be closed automatically, in current floe condition;Valving in current floe condition can be opened regularly, in circulation status;Valving in circulation status, in the case where the air-flow that gas circuit provides promotes, fluid can circulate in valving.It follows that the utility model can optionally carry out valve opening and closing, it is easy to the fluid in micro-fluidic chip to control.
Description
Technical field
A kind of valving is the utility model is related to, especially a kind of liquid control valve door for micro-fluidic chip fills
Put.
The utility model further relates to a kind of micro-fluidic chip.
Background technology
Immune lateral chromatography diagnostic techniques is adapted in various real-time test as a kind of stabilization and practical technology
(POCT)Or onsite application.
In immune series of strata reaction system, because system reason causes CV big, accurate quantification is unable to reach.And it is based on miniflow
The immune diagnostic method of control technology, it can effectively avoid above mentioned problem.
It is micro-fluidic and be divided to passive type and active two kinds.Passive type is micro-fluidic still to need capillary power to reach liquid
Lateral chromatography forward.But because the viscosity of different samples particularly whole blood sample is different, cause flow rate of liquid without legally constituted authority
One.
It is active micro-fluidic it is possible to prevente effectively from above mentioned problem, thrust forward can be given, liquid is uniformly flowed forward
It is dynamic, avoid because test value difference caused by different in flow rate.Meanwhile the manufacturing technique requirent of micro-fluidic chip is reduced, not so
Passive type is micro-fluidic very high to requirements such as the flatness of runner, and mismachining tolerance is very low.
Active micro-fluidic power has centrifugal force driving, electrowetting driving, pressure-driven(Be electrolysed pump, compressed gas pump,
Chemical breakdown pump, the driving of direct draught head)
But if to reach the purpose of arbitrarily control liquid velocity, not only to have motive force, also to there is Valve controlling, also
There is anti-return so as not to liquid because pressure removes, backflow is gone back.
Normally, micro-fluidic valve is divided into:Paraffin valve, paraffin hot melt valve, magnet mobile valve, operated pneumatic valve, machinery
Valve.Paraffin valve is generally used in the chip that liquid is driven by centrifugal force, and paraffin valve is opened by the impulse force top of centrifugal force.Stone
Wax hot melt valve is to orient heating valve position with thermals source such as laser, makes its dissolving, opens valve.Magnet mobile valve is to pass through magnetic
Motion of the iron under magnetic force environment carrys out controlled valve.Operated pneumatic valve is by gas inflated, makes a certain portion containing elastic component
Filling is heaved in position, plays the effect of valve.Machinery valve is coordinated by equipment and chip, is retracted by the stretching of equipment a certain
Position, chip is extruded, plays valve effect.
Existing micro-fluidic chip valving function is single, and stability is not high, only can just be prevented under closed mode
Liquid moves.
Combination required precision of some valves to micro-fluidic chip up and down is too high, can not realize large-scale production, size is slightly
Microvariations will cause Liquid valve to fail, and can not play the purpose for preventing liquid from flowing.
Or the valve having is disposable, can not repeat, for the micro-fluidic operation to complexity, disposable valve
Micro-fluidic runner design can be caused complicated, volume becomes big.It is unable to reach POCT exquisiteness and stable purpose.
The content of the invention
The technical problems to be solved in the utility model is:A kind of normally opened valve device for being used in micro-fluidic chip is provided,
It can trigger valving so that valving is changed into by normally open when sensing fluid and flowing through valving
Current floe condition;And when valving is in current floe condition, valving rear end chamber is in incubation as in micro-fluidic chip
The startup time of state, pass through timing, it can be ensured that the rear end chamber is at a quantity space in a special time
Complete to be incubated in section;Incubation terminates, i.e., after timing arrives, the foregoing valving in current floe condition of control is opened, valve
Fluid in the chamber of device rear end can enter front end chamber by the valving.Specifically, the utility model is in order to ensure
Micro-fluidic Liquid valve effect is, it is necessary to valving and equipment be combined closely, by having on the sealing ring and equipment of close membrane
The hold-down devices in face, play the purpose of controlled valve at any time, while ensure the needs of large-scale production, and valving will be to production
The requirement of technique is less high.Certainly, micro-fluidic chip locational space is limited, if can in the case where not losing and taking original function,
Integrated part functional module plays section space-efficient purpose.
Play an equipment simultaneously while operate the purpose of multiple micro-fluidic chips.Flux is improved, saves the time.
It can be removed semipermeable membrane device as the detection of liquid flowing state, made by the use of sealing ring made of conductive rubber
It is simple in construction in the case that chip retains original function, easily production.
To solve above-mentioned technical problem, the utility model will take following technical scheme:
A kind of liquid control valve door gear for micro-fluidic chip, including for sensing whether fluid flows through valving
The testing agency of installation site;The valving of normally open is in micro-fluidic chip, in the number that testing agency is fed back
When value shows that fluid flows through valving installation site, it can close automatically, in current floe condition;Valve in current floe condition
Device can be opened regularly, in circulation status;Valving in circulation status, in the case where the air-flow that gas circuit provides promotes,
Fluid can circulate in valving.
As further improvement of the utility model, in addition to press mechanism, seal;Described seal, for conduction
Sealing ring, including outer layer sealing ring, internal close membrane and probe contacts;Internal close membrane is in the inner ring of outer layer sealing ring;
Probe contacts are connected with outer layer sealing ring;Described press mechanism, including push-down head, the internally positioned close membrane of the push-down head it is upper
Side;The testing agency, including detection probe, the detection probe are connected with push-down head, and are located at the top of probe contacts,
The spacing being smaller than between push-down head and internal close membrane between detection probe and probe contacts simultaneously;Valving is installed
The micro-fluidic runner of opening position is divided into micro-valve liquid input section by micro-fluidic runner tabula and micro-valve goes out liquid section;Micro-valve liquid input section has
Liquid outlet, micro-valve, which goes out liquid section, has inlet;Internal close membrane can cover the liquid outlet of micro-valve liquid input section simultaneously, micro-valve goes out
The inlet of liquid section, and sealed by outer layer sealing ring;When press mechanism push-down head with detection probe towards conductive seal
When enclosing descending, when detection probe and probe contacts touch, press mechanism stopping is descending, now, push-down head and internal close membrane
Between spacing be present;When detection probe sensing data change, show that fluid be present flows through valving installed position
Micro-fluidic runner when, triggering press mechanism action, promote push-down head to continue traveling downwardly, until push-down head pushes down internal close membrane,
To seal the liquid outlet of micro-valve liquid input section simultaneously, micro-valve goes out the inlet of liquid section, and now valving is in current floe condition;Instantly
When gap be present between the push-down head of press mechanism and internal close membrane, valving is in open mode, and internal close membrane is had
Some deformation characteristics, it is ensured that fluid can flow out from the liquid outlet of micro-valve liquid input section, and the inlet that liquid section is gone out from micro-valve flows into.
As further improvement of the utility model, in addition to micro-valve Anti-backflow structure;The micro-valve Anti-backflow structure has
The micro-valve anti-return runner of insertion;The lower end of micro-valve anti-return runner is placed in the top of micro-fluidic runner tabula, and micro-valve is prevented back
Stream runner can respectively the liquid outlet with micro-valve liquid input section, micro-valve go out liquid section inlet it is corresponding connect;Micro-valve anti-return runner
Upper end have and be used to the caulking groove of seal be installed;Seal is flush-mounted in caulking groove, and internal close membrane covers micro-valve just
The upper end of anti-return runner, while internal close membrane has the space of free deformation.
As further improvement of the utility model, the inner chamber of micro-valve anti-return runner has micro-valve anti-return projection;It is micro-
Formed between the outer ring of valve anti-return projection and the inner chamber of micro-valve anti-return runner embedding for the sealing ring of installing outer layer sealing ring
Groove;Micro-valve anti-return projection has two insertion runners, and respectively micro-valve anti-return feed liquor runner, micro-valve anti-return goes out liquid stream
Road;The lower end of micro-valve anti-return feed liquor runner connects with the liquid outlet of micro-valve liquid input section, and micro-valve anti-return goes out under liquid stream road
The inlet that end then goes out liquid section with micro-valve connects;Outer layer sealing ring is inlaid in sealing ring caulking groove, and internal close membrane can be simultaneously
Cover the upper end of micro-valve anti-return feed liquor runner, micro-valve anti-return goes out the upper end in liquid stream road.
As further improvement of the utility model, the micro-valve Anti-backflow structure, with anti-return micro-valve installed position
Micro-fluidic runner split settings.
As further improvement of the utility model, the detection probe of testing agency is capacitance probe, and capacitance probe is under
Under the drive for pushing driving of press mechanism, it can be electrically connected with the probe contacts on seal.
As further improvement of the utility model, the valving is three-chip type structure, including from top to bottom successively
Upper strata chip, middle level chip and the next chip of distribution;Upper strata chip, middle level chip and next chip are mutually clamped two-by-two
Connection;Micro-valve Anti-backflow structure is arranged at middle level chip, and micro-fluidic runner is arranged in lower layer chip, and caulking groove is prevented back corresponding to micro-valve
Flow structure is arranged at the upper surface of middle level chip, and seal is pressed in caulking groove by upper strata chip, and upper strata chip corresponds to
Inner seal rings, detect contact position correspondence open up respectively pressure head walk hole, probe walk hole;And press mechanism is positioned at upper
The top of layer chip, press mechanism push, and drive push-down head to walk hole by pressure head, internal close membrane are pushed down, to seal micro-valve
The upper end of anti-return runner, now, anti-return micro-valve are closed;Capacitance probe direction with pushing for press mechanism
Upper strata chip movement, after walking hole up through the probe on the chip of upper strata, with the conductive seal being placed in the chip caulking groove of middle level
The probe contacts of circle touch, and realize and are electrically connected with.
Another technical purpose of the present utility model is a kind of micro-fluidic chip, including above-mentioned liquid control valve door dress
Put.
According to above-mentioned technical scheme, relative to prior art, the utility model has the following advantages:
The utility model creatively devises valving, it is necessary to which valving and equipment are combined closely, by having
Hold-down devices above the sealing ring and equipment of close membrane, play the purpose of controlled valve at any time, and may be reused.Together
When ensure the needs of large-scale production, the requirement that valving will be to production technology is less high.
Meanwhile can liquid flows to the opportunity of sealing ring in detection channel in time, accurately close sealing ring, you can exclude
Bubble before liquid, can throttle liquid again, play pellicle(Gas-permeable, liquid-impermeable)The effect of device.Save semipermeable membrane device
Functional module.
And have the effect of back-flow preventer concurrently, because runner is raised in valve.
Brief description of the drawings
Fig. 1 is the structural representation of the liquid control valve door gear described in the utility model for micro-fluidic chip;
Fig. 2 is the dimensional structure diagram of conductive seal circle in Fig. 1;
Fig. 3 is the structural representation in another direction of conductive seal circle in Fig. 1;
Fig. 4 is the section dimensional structure diagram of conductive seal circle;
Fig. 5 is the structural representation of lower layer chip in Fig. 1;
Fig. 6 is the structural representation of middle level chip in Fig. 1;
Fig. 7 is the section dimensional structure diagram in one direction of middle level chip;
Fig. 8 is the section dimensional structure diagram in middle level another direction of chip;
Fig. 9 is the section dimensional structure diagram in middle level another direction of chip;
In figure:Press mechanism 1, detection probe 2;Upper strata chip 3;Conductive seal circle 4;Outer layer sealing ring 4-1;Inside closing
Film 4-2;Capacitance probe contact 4-3;Middle level chip 5;Sealing ring caulking groove 5-1;Middle level chip runner 5-2;Lower layer chip 6;Miniflow
Flow control road 6-1.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the embodiment of the utility model is carried out
Clearly and completely describing, it is clear that described embodiment is only the utility model part of the embodiment, rather than whole
Embodiment.The description only actually at least one exemplary embodiment is illustrative to be never used as to this practicality below
New and its application or any restrictions used.Based on the embodiment in the utility model, those of ordinary skill in the art are not having
There is the every other embodiment made and obtained under the premise of creative work, belong to the scope of the utility model protection.Unless
Illustrate in addition, part and the positioned opposite of step, expression formula and the unlimited system of numerical value otherwise illustrated in these embodiments
The scope of the utility model.Simultaneously, it should be appreciated that for the ease of description, the size of the various pieces shown in accompanying drawing is not
It is to be drawn according to the proportionate relationship of reality.May for technology, method and apparatus known to person of ordinary skill in the relevant
It is not discussed in detail, but in the appropriate case, the technology, method and apparatus should be considered as authorizing part for specification.
In shown here and discussion all examples, any occurrence should be construed as merely exemplary, not as limit
System.Therefore, the other examples of exemplary embodiment can have different values.
For the ease of description, space relative terms can be used herein, as " ... on ", " ... top ",
" ... upper surface ", " above " etc., for describing such as a device shown in the figure or feature and other devices or spy
The spatial relation of sign.It should be appreciated that space relative terms are intended to comprising the orientation except device described in figure
Outside different azimuth in use or operation.For example, if the device in accompanying drawing is squeezed, it is described as " in other devices
It will be positioned as " under other devices or construction after the device of part or construction top " or " on other devices or construction "
Side " or " under other devices or construction ".Thus, exemplary term " ... top " can include " ... top " and
" in ... lower section " two kinds of orientation.The device can also other different modes positioning (being rotated by 90 ° or in other orientation).
As shown in figs 1-9, the liquid control valve door gear described in the utility model for micro-fluidic chip, for anti-
The anti-return micro-valve of backflow functionality;Including press mechanism 1, testing agency, seal and micro-valve Anti-backflow structure;Wherein:
Described press mechanism 1, including push-down head, the internally positioned close membrane 4-2 of push-down head top.
The testing agency, including detection probe 2, the detection probe 2 are connected with push-down head, and are located at probe contacts
Top, while the spacing being smaller than between push-down head and internal close membrane 4-2 between detection probe 2 and probe contacts.
Described seal is conductive seal circle 4, including outer layer sealing ring 4-1, internal close membrane 4-2 and capacitance probe
Contact 4-3;Internal close membrane 4-2 is in outer layer sealing ring 4-1 inner ring, and capacitance probe contact 4-3 then with outer layer sealing ring
4-1 connections.
The micro-valve Anti-backflow structure, the micro-fluidic runner 6-1 split settings with anti-return micro-valve installed position, including
The micro-valve anti-return runner of insertion;
The micro-fluidic runner 6-1 of the anti-return micro-valve installed position is divided into micro-valve feed liquor by micro-fluidic runner tabula
Section and micro-valve go out liquid section;Micro-valve liquid input section has liquid outlet, and micro-valve, which goes out liquid section, has inlet;
The lower end of micro-valve anti-return runner is placed in the top of micro-fluidic runner tabula, and micro-valve anti-return runner can be distinguished
Liquid outlet, micro-valve with micro-valve liquid input section go out liquid section inlet it is corresponding connection;
In the utility model, the inner chamber of micro-valve anti-return runner has micro-valve anti-return projection;Micro-valve anti-return projection
The sealing ring caulking groove 5-1 for installing outer layer sealing ring 4-1 is formed between outer ring and the inner chamber of micro-valve anti-return runner;Micro-valve is prevented
Reflow bump has two insertion runners, and respectively micro-valve anti-return feed liquor runner, micro-valve anti-return goes out liquid stream road;Micro-valve is prevented back
The lower end for flowing into liquid stream road connects with the liquid outlet of micro-valve liquid input section, and the lower end that micro-valve anti-return goes out liquid stream road then goes out with micro-valve
The inlet connection of liquid section;Outer layer sealing ring 4-1 is inlaid in sealing ring caulking groove 5-1, and internal close membrane 4-2 can be covered simultaneously
Firmly the upper end of micro-valve anti-return feed liquor runner, micro-valve anti-return go out the upper end in liquid stream road;
When the utility model not equipped Anti-backflow structure, described inside close membrane 4-2 can cover micro-valve simultaneously
The liquid outlet of liquid input section, micro-valve go out the inlet of liquid section, and are sealed by outer layer sealing ring 4-1.
The detection probe 2 of testing agency touches with the pressing action of press mechanism 1 with capacitance probe contact 4-3;At any time
Whether detection liquid is flowed in valve.Now, anti-return micro-valve is in open mode.In fact, in the push-down head of press mechanism 1
In the case of spacing being present between internal close membrane 4-2, due to the internal close membrane 4-2 deformation functions having in itself and peace
The deformation space having at holding position, causes under the drive of air-flow, and fluid can overcome internal closing from micro-valve liquid input section
After film 4-2 deformation, go out liquid section into micro-valve.
When connecting gas circuit, under the air pressure driving that gas circuit provides, liquid moves forward, the fluid warp in micro-valve liquid input section
After micro-valve anti-return runner, it flow to micro-valve and goes out liquid section, the capacitance probe in testing agency, detects that liquid flow comes, again
Press mechanism 1 is triggered, under the drive for pushing driving, internal close membrane 4-2 seals the upper end of micro-valve anti-return runner, this
When, anti-return micro-valve is closed;
Testing agency includes capacitance probe, and capacitance probe, can be with electric capacity under the drive for pushing driving of press mechanism 1
Probe contacts 4-3 is electrically connected with.
Specifically:When the push-down head of press mechanism 1 is descending towards conductive seal circle 4 with detection probe 2, visited in detection
First 2 with probe contacts when touching, and press mechanism 1 stops descending, now, spacing be present between push-down head and internal close membrane 4-2;
When detection probe 2 sense data change, show the micro-fluidic runner that fluid flows through valving installed position be present
During 6-1, triggering press mechanism 1 acts, and promotes push-down head to continue traveling downwardly, until push-down head pushes down internal close membrane 4-2, with simultaneously
Seal the liquid outlet of micro-valve liquid input section, micro-valve goes out the inlet of liquid section, now valving is in current floe condition;Work as press mechanism
When gap be present between 1 push-down head and internal close membrane 4-2, valving is in open mode, and internal close membrane 4-2 is had
Some deformation characteristics, it is ensured that fluid can flow out from the liquid outlet of micro-valve liquid input section, and the inlet that liquid section is gone out from micro-valve flows into.
In accompanying drawing, the valving is three-chip type structure, including be sequentially distributed from top to bottom upper strata chip 3, middle level
Chip 5 and next chip;Upper strata chip 3, middle level chip 5 and next chip are mutually clamped connection two-by-two;Micro-valve anti-return
For structure setting in middle level chip 5, micro-fluidic runner 6-1 is arranged in lower layer chip 6, and caulking groove is set corresponding to micro-valve Anti-backflow structure
In the upper surface of middle level chip 5, seal is pressed in caulking groove by upper strata chip 3, and upper strata chip 3 corresponds to inner sealing
Open up pressure head respectively with enclosing, detect the position correspondence of contact walk hole, pop one's head in and walk hole;And press mechanism 1 is located at upper strata chip 3
Top, press mechanism 1 pushes, and drives push-down head to walk hole by pressure head, pushes down internal close membrane 4-2, prevented with sealing micro-valve
The upper end of backflow runner, now, anti-return micro-valve is closed;Capacitance probe pushes and direction with press mechanism 1
Upper strata chip 3 moves, conductive close in the chip caulking groove of middle level with being placed in after walking hole up through the probe on upper strata chip 3
The probe contacts of seal 4 touch, and realize and are electrically connected with.
The utility model creatively devises valving, itself and the control back-flow preventer fusion of micro-fluidic liquid is existed
Together, micro-fluidic chip space is saved.The locational space of micro-fluidic chip is extremely limited, and the utility model can effectively be saved micro-
Flow control road 6-1 spaces are flowed, it is more efficient when can make design runner.Avoid liquid flow caused by hypotelorism between each runner
Road bad sealing, flow road the problem of.
The utility model utilizes the electric conductivity of conductive rubber material, the capacitance detecting probe 2 of bonding apparatus, observes in runner
Liquid flow to the exact moment of valve, closes valve in time.Save semipermeable membrane device.
Claims (8)
1. a kind of liquid control valve door gear for micro-fluidic chip, it is characterised in that including for sensing whether fluid flows
Testing agency through valving installation site;
The valving of normally open is in micro-fluidic chip, valve is flowed through in the numerical tabular free flow body that testing agency is fed back
During door gear installation site, it can close automatically, in current floe condition;
Valving in current floe condition can be opened regularly, in circulation status;
Valving in circulation status, in the case where the air-flow that gas circuit provides promotes, fluid can circulate in valving.
2. the liquid control valve door gear according to claim 1 for micro-fluidic chip, it is characterised in that under also including
Press mechanism, seal;
Described seal, is conductive seal circle, including outer layer sealing ring, internal close membrane and probe contacts;Inside closing
Film is in the inner ring of outer layer sealing ring;Probe contacts are connected with outer layer sealing ring;
Described press mechanism, including push-down head, the top of the internally positioned close membrane of the push-down head;
The testing agency, including detection probe, the detection probe are connected with push-down head, and positioned at the upper of probe contacts
Side, while the spacing being smaller than between push-down head and internal close membrane between detection probe and probe contacts;
The micro-fluidic runner of valving installed position is divided into micro-valve liquid input section by micro-fluidic runner tabula and micro-valve goes out liquid
Section;
Micro-valve liquid input section has liquid outlet, and micro-valve, which goes out liquid section, has inlet;
Internal close membrane can cover the liquid outlet of micro-valve liquid input section simultaneously, micro-valve goes out the inlet of liquid section, and pass through outer layer
Sealing ring seals;
When the push-down head of press mechanism is descending towards conductive seal circle with detection probe, in detection probe and probe contacts phase
When touching, press mechanism stopping is descending, now, spacing be present between push-down head and internal close membrane;When the number of detection probe sensing
According to changing, when showing to exist the micro-fluidic runner that fluid flows through valving installed position, triggering press mechanism action,
Push-down head is promoted to continue traveling downwardly, until push-down head pushes down internal close membrane, to seal liquid outlet, the micro-valve of micro-valve liquid input section simultaneously
Go out the inlet of liquid section, now valving is in current floe condition;
When gap be present between the push-down head of press mechanism and internal close membrane, valving is in open mode, inside envelope
Close deformation characteristics possessed by film, it is ensured that fluid can be flowed out from the liquid outlet of micro-valve liquid input section, and the feed liquor of liquid section is gone out from micro-valve
Mouth flows into.
3. the liquid control valve door gear according to claim 2 for micro-fluidic chip, it is characterised in that also including micro-
Valve Anti-backflow structure;The micro-valve Anti-backflow structure has the micro-valve anti-return runner of insertion;
The lower end of micro-valve anti-return runner is placed in the top of micro-fluidic runner tabula, and micro-valve anti-return runner can respectively with it is micro-
The liquid outlet of valve liquid input section, micro-valve go out the corresponding connection of inlet of liquid section;
The upper end of micro-valve anti-return runner has the caulking groove for being used for installing seal;
Seal is flush-mounted in caulking groove, and internal close membrane covers the upper end of micro-valve anti-return runner, while internal envelope just
Closing film has the space of free deformation.
4. the liquid control valve door gear according to claim 3 for micro-fluidic chip, it is characterised in that micro-valve is prevented back
The inner chamber of stream runner has micro-valve anti-return projection;
Formed between the outer ring of micro-valve anti-return projection and the inner chamber of micro-valve anti-return runner for installing the close of outer layer sealing ring
Seal caulking groove;
Micro-valve anti-return projection has two insertion runners, and respectively micro-valve anti-return feed liquor runner, micro-valve anti-return goes out liquid stream
Road;
The lower end of micro-valve anti-return feed liquor runner connects with the liquid outlet of micro-valve liquid input section, and micro-valve anti-return goes out under liquid stream road
The inlet that end then goes out liquid section with micro-valve connects;
Outer layer sealing ring is inlaid in sealing ring caulking groove, and internal close membrane can cover micro-valve anti-return feed liquor runner simultaneously
Upper end, micro-valve anti-return go out the upper end in liquid stream road.
5. the liquid control valve door gear for micro-fluidic chip according to claim 3 or 4, it is characterised in that described
Micro-valve Anti-backflow structure, the micro-fluidic runner split settings with anti-return micro-valve installed position.
6. the liquid control valve door gear according to claim 5 for micro-fluidic chip, it is characterised in that testing agency
Detection probe be capacitance probe, capacitance probe, can be with the spy on seal under the drive for pushing driving of press mechanism
Head contact is electrically connected with.
7. the liquid control valve door gear according to claim 6 for micro-fluidic chip, it is characterised in that the valve
Device is three-chip type structure, including upper strata chip, middle level chip and the next chip being sequentially distributed from top to bottom;Upper strata core
Piece, middle level chip and next chip are mutually clamped connection two-by-two;
Micro-valve Anti-backflow structure is arranged at middle level chip, and micro-fluidic runner is arranged in lower layer chip, and caulking groove is prevented back corresponding to micro-valve
Flow structure is arranged at the upper surface of middle level chip, and seal is pressed in caulking groove by upper strata chip, and upper strata chip corresponds to
Inner seal rings, detect contact position correspondence open up respectively pressure head walk hole, probe walk hole;And press mechanism is positioned at upper
The top of layer chip;
Press mechanism pushes, and drives push-down head to walk hole by pressure head, internal close membrane is pushed down, to seal micro-valve anti-return runner
Upper end, now, anti-return micro-valve is closed;
Capacitance probe moves with pushing for press mechanism and towards upper strata chip, is walked up through the probe on the chip of upper strata
Kong Hou, the probe contacts of the conductive seal circle with being placed in the chip caulking groove of middle level touch, and realize and are electrically connected with.
8. a kind of micro-fluidic chip, it is characterised in that including the liquid control described in any one claim in claim 1-7
Valving processed.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201720340435.XU CN206631607U (en) | 2017-04-01 | 2017-04-01 | Liquid control valve door gear and its micro-fluidic chip for micro-fluidic chip |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201720340435.XU CN206631607U (en) | 2017-04-01 | 2017-04-01 | Liquid control valve door gear and its micro-fluidic chip for micro-fluidic chip |
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CN206631607U true CN206631607U (en) | 2017-11-14 |
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CN201720340435.XU Withdrawn - After Issue CN206631607U (en) | 2017-04-01 | 2017-04-01 | Liquid control valve door gear and its micro-fluidic chip for micro-fluidic chip |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108169301A (en) * | 2018-03-15 | 2018-06-15 | 宁波雪弗尔生物科技有限公司 | A kind of high-throughput quantification detects the closed experimental system setup of nucleic acid reaction |
CN110756235A (en) * | 2019-11-13 | 2020-02-07 | 河南科技大学 | Microfluidic control valve capable of adding liquid and microfluidic chip |
-
2017
- 2017-04-01 CN CN201720340435.XU patent/CN206631607U/en not_active Withdrawn - After Issue
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108169301A (en) * | 2018-03-15 | 2018-06-15 | 宁波雪弗尔生物科技有限公司 | A kind of high-throughput quantification detects the closed experimental system setup of nucleic acid reaction |
CN110756235A (en) * | 2019-11-13 | 2020-02-07 | 河南科技大学 | Microfluidic control valve capable of adding liquid and microfluidic chip |
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