CN206548640U - Simply, safe tree shrew gavage device - Google Patents

Simply, safe tree shrew gavage device Download PDF

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Publication number
CN206548640U
CN206548640U CN201621103316.4U CN201621103316U CN206548640U CN 206548640 U CN206548640 U CN 206548640U CN 201621103316 U CN201621103316 U CN 201621103316U CN 206548640 U CN206548640 U CN 206548640U
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China
Prior art keywords
stomach tube
tree shrew
syringe
gavage
stomach
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CN201621103316.4U
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Chinese (zh)
Inventor
叶尤松
唐东红
李哲丽
王陈芸
黄璋琼
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Institute of Medical Biology of CAMS and PUMC
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Institute of Medical Biology of CAMS and PUMC
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Abstract

The utility model discloses a kind of simple, safety tree shrew gavage device, including syringe, stomach tube and opener, the endcapped of the stomach tube is simultaneously provided with aperture in end profile, head end is the openend of connection syringe pin hole, openend carries flexible glue lid, the gavage medicine that injector syringe is connected in openend, syringe after flexible glue lid is opened to reach in stomach by stomach tube.This gavage device combines the dietary habit of tree shrew, small-bore people is applied to tree shrew with silica gel stomach tube, damage tree Shrew gastrointestinal mucosals are difficult when throwing pipe while easily can insert the stomach tube other end in sterilized water, once occurring mispluging in tracheae situation water and will produce bubble, there is suggesting effect for the operation error of staff, reduce the situation for mispluging tracheae, improve security, because tree shrew tooth is sharp, Baoding that opener is beneficial to tree shrew is added, being smoothed out for gavage has been ensured;Prepared by the utility model convenient, and cost is low, safety simple to operate.

Description

Simply, safe tree shrew gavage device
Technical field
The utility model belongs to experimental animal instrument field, more particularly to a kind of simple, safety tree shrew gavage device.
Background technology
Tree shrew has small, easily raises, management is convenient, cheap economical, and its evolution degree is high, metabolism and substantially Dissection is than animals and human beingses such as dog, big mouse more closely, anatomical structure is also similar to people, and therefore, it is used as comparatively ideal reality Animal is tested, has been widely used in the research of Med Biol.Zoopery utilization in, according to evaluate purpose, The difference of pharmaceutical dosage form, dosage, can take tree shrew different medications, and the medication of oral gavage is a kind of among these Very important approach.Prior art is usually using a kind of special hollow needle with standard syringe interface.Using this During kind of irrigation stomach device, the decoction of syringe cavity will be drawn into via being properly inserted into animal esophagus by pushing syringe handle In the hollow needle and be expelled to the stomach of experimental animal.But the rigid structure of this irrigation stomach device, experimental animal can be disappeared Change road and produce a certain degree of injury.Secondly, tree shrew natural disposition agility is active, tooth is sharp, and patient can not fix gavage dress very well Put, the generation for situations such as causing gavage failure, misplug tracheae, gastrointestinal mucosal more macrolesion, so as to be difficult to objective evaluation experiment The pharmacology and toxicologic index of medication.
The content of the invention
The utility model is intended to fill there is provided a kind of simple, safety tree shrew for above-mentioned the deficiencies in the prior art Stomach device, the gavage device is used for the gavage for testing tree shrew, has not only ensured being smoothed out for gavage, and can avoid filling Tree shrew is damaged during stomach and simple, easy to use.
The utility model is achieved through the following technical solutions:
A kind of simple, safety tree shrew gavage device, including syringe, stomach tube and opener, the end envelope of the stomach tube Close and be provided with aperture in end profile, head end is the openend of connection syringe pin hole, and openend carries flexible glue lid, opens flexible glue The gavage medicine that injector syringe is connected in openend, syringe after lid is reached in stomach by stomach tube.
It is preferred that, the stomach tube be disposable people's stomach tube, made by the silica gel material of soft texture, to mucous membrane of animal without Damage, internal diameter 1mm.
It is preferred that, the opener selection does not damage the passivity batten of tree shrew tooth and oral mucosa, long generous for 10cm ×1cm×0.5cm;The through hole greater diameter than stomach tube is opened in stage casing, stomach tube is inserted in through hole.The opener both ends are used Flexible material, flexibility is fixed on tree shrew oral cavity, stomach tube via through holes is passed through oral cavity, and reaching stomach into esophagus is finally completed Medicine gavage.
It is preferred that, the big I of syringe is arbitrarily changed, dosage easy to control.
This gavage device that the utility model is provided can be used in testing tree shrew, and this gavage device combines the life of tree shrew Life habit is managed, small-bore people is applied to tree shrew with silica gel stomach tube, damage tree Shrew gastrointestinal mucosals are difficult while can when throwing pipe Easily the stomach tube other end is inserted in sterilized water, once bubble will be produced by occurring mispluging in tracheae situation water, for work people The operation error of member has suggesting effect, reduces the situation for mispluging tracheae, improves security, because tree shrew tooth is sharp, increases Add opener to be beneficial to Baoding of tree shrew, ensure being smoothed out for gavage;It can avoid causing tree shrew during gavage Injury, has accomplished simple and safe and convenient to use.Prepared by the utility model convenient, and cost is low, safety simple to operate.
Brief description of the drawings
Fig. 1 is combination diagram of the present utility model.
Embodiment
Below in conjunction with the accompanying drawings 1 and specific embodiment further describe the utility model, advantage of the present utility model and spy Point will be with description and it is apparent.But the following examples are only exemplary, not to protection model of the present utility model Enclose any limitation of composition.
The present embodiment is used exclusively for testing a specific embodiment of tree shrew gavage device.
The present apparatus is divided into three parts:2ml syringes 1, the disposable people of long 15cm are with No. 6 stomach tubes 2 and opener 3.It is described Disposable people opens an aperture 2mm apertures 4 with No. 6 stomach tubes 2, internal diameter 1mm endcapped in the end profile, other end Head end is openend 5 and is provided with flexible glue lid 7, and openend is the construction of connection injector syringe;Flexible glue lid 7 is used for closing open end 5, flexible glue lid opens rear open end and injector syringe connection, and stomach tube openend 5 is rotatably coupled into going out for the syringe of syringe 1 Mouthful.The opener 3 need to combine tree shrew oral cavity structure, and selection is beneficial to fixed tree shrew oral cavity, and tree shrew tooth is not damaged and oral cavity is viscous The passivity wood materials of film, it is long generous for 10cm × 1cm × 0.5cm;The through hole 6 greater diameter than stomach tube 2mm is chiseled on opener, Make it allow stomach tube to pass through opener and reach stomach into tree shrew oesophagus.
During gavage, the volume of the long stomach tubes of 15cm is measured first, is then opened tree shrew oral cavity with opener 3, is passed through opener On through hole 6 will scribble the stomach tube insertion tree shrew stomach bottom of lubricant, swallow about 5cm, open flexible glue lid 7, stomach tube is inserted prior In the sterile distilled water got ready, the situation of mispluging is determined whether, once bubble will be produced by occurring mispluging in tracheae situation water, then The suction meter of syringe 1 determines the particle supensoid agent that volume adds the PBS or similar buffer solution of stomach tube volume to be resuspended, and is connected to stomach tube 2 exposed openends 5, medicine are pushed into the stomach of tree shrew;Then it is slow to extract stomach tube 2, complete gavage.
The present embodiment provides the advantage of tree shrew gavage device:Stomach tube 2 is made by the silica gel material of soft texture, to animal Mucous membrane not damaged, arbitrarily changes direction and is easy to detect whether to misplug phenomenon, stomach pipe end by the openend 5 of syringe spline structure Closing, lateral opening is easy to medicaments uniformity to enter animal stomach.
The flexible fixed tree shrew oral cavity of opener 3, makes stomach tube via through holes 6 pass through oral cavity, and reaching stomach into esophagus protects Being smoothed out for gavage is hindered, and can avoid damaging tree shrew during gavage, accomplished simple and used Safe ready.
After present apparatus gavage, experiment does not occur malaise symptoms with tree shrew.

Claims (1)

1. a kind of simple, safety tree shrew gavage device, including syringe(1), stomach tube(2)And opener(3), its feature It is, the stomach tube(2)For disposable people's stomach tube, made by the silica gel material of soft texture, internal diameter 1mm;The stomach tube(2) Endcapped is simultaneously provided with aperture in end profile(4), head end is connection syringe(1)The openend of pin hole(5), openend(5) With flexible glue lid(7), open flexible glue lid(7)Afterwards by syringe(1)Syringe is connected to openend(5), syringe(1)Interior gavage Medicine passes through stomach tube(2)Reach in stomach;
The opener(3)Selection does not damage the passivity batten of tree shrew tooth and oral mucosa, it is long it is generous for 10cm × 1cm × 0.5cm;Opened in stage casing greater diameter than stomach tube(2)Through hole(6), stomach tube(2)Insert in through hole(6)In.
CN201621103316.4U 2016-10-09 2016-10-09 Simply, safe tree shrew gavage device Active CN206548640U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621103316.4U CN206548640U (en) 2016-10-09 2016-10-09 Simply, safe tree shrew gavage device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621103316.4U CN206548640U (en) 2016-10-09 2016-10-09 Simply, safe tree shrew gavage device

Publications (1)

Publication Number Publication Date
CN206548640U true CN206548640U (en) 2017-10-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201621103316.4U Active CN206548640U (en) 2016-10-09 2016-10-09 Simply, safe tree shrew gavage device

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108013949A (en) * 2017-12-29 2018-05-11 中国医学科学院北京协和医院 Lavage device for animal and its operating method
CN109350296A (en) * 2018-10-12 2019-02-19 江汉大学 Accurate noninvasive irrigation stomach device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108013949A (en) * 2017-12-29 2018-05-11 中国医学科学院北京协和医院 Lavage device for animal and its operating method
CN109350296A (en) * 2018-10-12 2019-02-19 江汉大学 Accurate noninvasive irrigation stomach device
CN109350296B (en) * 2018-10-12 2024-04-30 江汉大学 Precision noninvasive stomach irrigator

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