CN206508065U - Rat fixator - Google Patents

Rat fixator Download PDF

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Publication number
CN206508065U
CN206508065U CN201621271107.0U CN201621271107U CN206508065U CN 206508065 U CN206508065 U CN 206508065U CN 201621271107 U CN201621271107 U CN 201621271107U CN 206508065 U CN206508065 U CN 206508065U
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CN
China
Prior art keywords
bottom plate
fixed
rat
fixed bottom
net
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Expired - Fee Related
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CN201621271107.0U
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Chinese (zh)
Inventor
魏彤
魏群利
何琳琳
时瑞
张宗玉
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Xuzhou Medical University
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Xuzhou Medical University
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Priority to CN201621271107.0U priority Critical patent/CN206508065U/en
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Publication of CN206508065U publication Critical patent/CN206508065U/en
Expired - Fee Related legal-status Critical Current
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Abstract

A kind of rat fixator, including fixed bottom plate (1) and fixed net (2), the middle part of the fixed net (2) is curvedly bent to away from fixed bottom plate (1) direction, the rear end edge of fixed net (2) is hinged with being fixedly installed on the hinge ring (3) of fixed bottom plate (1) upper surface posterior edges, the quantity at least two of the hinge ring (3), fixed bottom plate (1) upper surface forward edge is fixedly installed a hook (4) that net (2) front end edge is fixed for twisting, the quantity at least two of the hook (4), fixed bottom plate (1) upper surface right side central is fixedly installed the barrier plate (5) of fore-and-aft direction stretching, extension, fixed bottom plate (1) upper surface left side central portion is abreast fixedly installed two steady stern posts (6), two steady stern post (6) left parts are provided with two elastic webbings (7).The fixator fixed performance is good, and rat is fixed and injures small, the success rate and reliability of experiment can be improved, can be convenient for kinds of experiments application.

Description

Rat fixator
Technical field
The utility model is related to fixing device, and in particular to a kind of rat fixator.
Background technology
The teaching and scientific research of functional subjects correlation are one of doctor, the important process content of pharmacy relevant speciality.Inspire and train Student's Creative Thinking is supported, updates and develops the developing direction that functional subjects experimental method is following discipline construction.At present, undergraduate course Raw experimental teaching form is that experimental procedure is improved to be easy to student to operate mostly, this allow for the important experiment content in part because Instrument lacks or does not apply to and have to simplify or give up, and does not reach the requirement of teaching.Therefore, existing instrument is improved and Innovation, can not only training student divergent thinking, raising starts and operational capacity, and can create higher social and economy Value.
In teaching experiment, often rat is regard as sheet, two's physiology, Pathological Physiology, pharmacological experimental subjects. Experiment is strong with rat invasive, and disposition is more violent, is easily stung to fury, is difficult to fix, and rat seizure fixation is conventional basic Laboratory facilities.Tail vein injection, intraperitoneal injection, acupuncture etc. are again conventional experimental implementations.On the one hand, the science for being related to rat is ground Study carefully, it is desirable to high to the fineness of operation, the accuracy at administration and Focal drug-block position is high, it is desirable to dosage to Conscious Rat and The stability of operation technique is high;On the other hand, experiment of the rat under narcosis, anaesthetic dosage is difficult to control to, animal dead Rate is high, influences the accuracy of experiment, and some experiments such as anti-inflammatory experiment and chlorpromazine are to basic metabolism and the influence of body temperature Also require that and use Conscious Rat.Due to student first contacts experimental animal, all be present some problems in psychology and technical elements, test During contact nearer with rat, students' skill is not familiar, operate it is unskilled, both add potential safety hazard, teaching had a strong impact on again Quality.In anti-inflammatory realization most of students' unions foot bottom egg white injection precision is poor caused by rat fixes difficulty, toes thickness or Volume determination error rate is big and causes the failure of an experiment.How on the premise of safe and feasible, the items for being related to rat are smoothly completed Experiment, this is the problem that must be faced in experimentation.And presently commercially available rat fixator, more based on tubular, space envelope Close, function is single, it is big to rat nocuity, do not meet the optimization principles of " 3R " (reduce, substitute, optimizing) and the human relations of experimental animal Neo-Confucianism is required.Existing tubular fixator, rat ear is inserted to be fixed when it fixes rat head by iron bolt more, by Nocuity has been carried out to rat to fix, so easily producing pessimal stimulation to rat, and then be easily caused rat in experiment in it During occur head revolution sting people's situation, in addition, this nocuity fixed form is easily caused the death of rat.Existing rat Rat foot is fixed more by way of making the foot of rat and passing through preformed hole for fixator, due to other no auxiliary Fixation, causes rat foot easily to be shaken off from hole.In addition, present rat fixator function is single, list can only be carried out more One property is tested, and generally requires to purchase polytype fixator when carrying out multinomial experiment, so as to add experimental cost.
The content of the invention
In view of the above-mentioned problems of the prior art, the utility model provides a kind of rat fixator, the fixator is fixed Performance is good, can prevent rat from shaking off in experimentation, and can be effectively prevented from the situation that people is stung in rat revolution in experimentation Occur, the fixator can mitigate the pessimal stimulation to rat body, it is fixed to rat injures small, can be in the shape that need not be anaesthetized Related experiment is can be carried out under state, so as to reduce the higher death rate caused by Anesthetic factor, experiment can be improved Success rate and reliability, in addition, the fixator is vdiverse in function, can be convenient for kinds of experiments application, its low manufacture cost, general Property it is strong, be convenient for promoting.
To achieve these goals, the utility model provides a kind of rat fixator, including fixed bottom plate and fixed net, institute The middle part for stating fixed net is curvedly bent to away from fixed bottom plate direction, and the rear end of fixed net is along with being fixedly installed on fixed bottom The hinge ring of plate upper surface posterior edges is hinged, the quantity at least two of the hinge ring, the fixed plate upper surface front side edge Edge, which is fixed with least two, is used for the hook that twisting fixes net front end edge, and fixed plate upper surface right side central is fixedly installed The barrier plate that fore-and-aft direction stretches, fixed plate upper surface left side central portion is abreast fixedly installed two steady stern posts, and two steady Stern post left part is provided with two elastic webbings.
In the technical scheme, coordinate fixed rat with fixed bottom plate by making to fix net, it is ensured that rats breathing It is smooth, and then it is avoided that the situation of asphyxia occurs.It is real that fixed online mesh can be convenient for acupuncture in rat up to after fixing Test.The cooperation of barrier plate and two steady stern posts can hinder rat play forward or backward after fixation, so as to add fixation Stability;In addition, two steady stern posts can fix the buttocks of rat, consequently facilitating tail vein injection and taking blood.Two bullets Property band setting, can be in order to the fixation of rat heel portion, so as to be convenient for rat paw edema experiment, the heel of rat Not only scorching medicine can be caused in order to disposable success albumen injection after portion's fixation, meanwhile, it can also be easy to static by slide measure Measurement.The fixator can stably fix rat, can not only prevent rat from shaking off in experimentation, and can effectively keep away Exempt from the situation generation that people is stung in rat revolution in experimentation, the fixator can mitigate the pessimal stimulation to rat body, and it is to big Mouse, which is fixed, injures small, related experiment can be can be carried out in the state of it need not anaesthetize, so as to reduce because of Anesthetic factor institute The caused higher death rate, can improve the success rate and reliability of experiment, in addition, the fixator is vdiverse in function, can be easy into Row kinds of experiments application, its low manufacture cost, highly versatile, be convenient for promote.
Further, for the ease of the rat after fixation is injected intraperitoneally, the position kept left in the middle part of the fixed bottom plate The intraperitoneal injection hole of its thickness direction is provided through, intraperitoneal injection hole position is in the right side of steady stern post.
Further, in order that the fixator can be adapted to various sizes of rat, to increase the versatility of the fixator, also wrap The regulation stud being vertically fixedly installed on fixed bottom plate is included, the regulation stud is located in the middle part of fixed bottom plate and close to fixed Net and be equipped with nut in the position on rear end edge, regulation stud.
Further, in order to improve injection precision, the intraperitoneal injection hole is obliquely set from left to right from top to bottom, and it inclines Rake angle is 45 degree.
Further, in order to increase the stationarity of fixed bottom plate, meanwhile, also for can more easily take the fixator, institute The lower surface outer rim for stating fixed bottom plate is provided with multiple bearings.
As a preferred embodiment, the cross section of the fixed bottom plate is rectangular.
As a preferred embodiment, the vertical section of the barrier plate is the low circular arc in the high two ends in middle part.
Further, in order to improve the effect of fixed rat heel portion, two elastic webbings are located at before and after two steady stern posts respectively The outside in direction.
Further, in order to can guarantee that experiment effect, and the gross weight of fixator, the fixed bottom plate and stop can be reduced Plate is made by hard plastic board.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
In figure:1st, fixed bottom plate, 2, fixed net, 3, hinge ring, 4, hook, 5, barrier plate, 6, steady stern post, 7, elastic webbing, 8, It is injected intraperitoneally hole, 9, regulation stud, 10, bearing.
Embodiment
The utility model is described in further detail below in conjunction with the accompanying drawings.
As shown in figure 1, a kind of rat fixator, including fixed bottom plate 1 and fixed net 2, the middle part of the fixed net 2 is in arc Bent to away from the fixed direction of bottom plate 1 to shape, the rear end of fixed net 2 is along with being fixedly installed on the fixed upper surface back side edge of bottom plate 1 The hinge ring 3 of edge is hinged, the quantity at least two of the hinge ring 3, the fixed upper surface forward edge of bottom plate 1 be fixed with to Few two are used for the hook 4 that twisting fixes the front end edge of net 2, and the fixed upper surface right side central of bottom plate 1 is fixedly installed fore-and-aft direction The barrier plate 5 of stretching, extension, the fixed upper surface left side central portion of bottom plate 1 is abreast fixedly installed two steady stern posts 6, two steady stern posts 6 Left part is provided with two elastic webbings 7.Two elastic webbings 7 can be by being arranged on the through hole on fixed bottom plate 1 by fixing bottom plate 1 Bottom penetrates top, and then an elastic sleeve can be formed on the top of fixed bottom plate 1, so can be at the bottom of fixed bottom plate 1 Portion tenses elastic band 7 and the foot of rat is fixed;Elastic band 7 can also be directly set to be fixed on the upper table of fixed bottom plate 1 Face, makes each elastic band 7 have two free ends in one end away from fixed bottom plate 1, so passes through two free ends of tie-down The foot of rat is fixed mode.Coordinate fixed rat with fixed bottom plate 1 by making to fix net 2, it is ensured that rat exhales That inhales is smooth, and then is avoided that the situation of asphyxia occurs.Mesh on fixed net 2 can be convenient for pin in rat up to after fixing Moxibustion is tested.The cooperation of barrier plate 5 and two steady stern posts 6 can hinder rat play forward or backward after fixation, so as to increase Fixed stability;In addition, two steady stern posts 6 can fix the buttocks of rat, consequently facilitating tail vein injection and taking blood. The setting of two elastic webbings 7, can be tested, greatly in order to the fixation of rat heel portion so as to be convenient for rat paw edema Not only scorching medicine can be caused in order to disposable success albumen injection after the heel portion fixation of mouse, meanwhile, it can also be easy to by vernier Slide calliper rule static measurement.The fixator can stably fix rat, can not only prevent rat from shaking off in experimentation, Er Qieneng The situation generation that people is stung in rat revolution in experimentation is effectively prevented from, the fixator can mitigate the bad thorn to rat body Swash, it is fixed to rat injures small, related experiment can be can be carried out in the state of it need not anaesthetize, so as to reduce because of fiber crops The higher death rate caused by liquor-saturated factor, can improve the success rate and reliability of experiment, in addition, the fixator is vdiverse in function, Kinds of experiments application can be convenient for, its low manufacture cost, highly versatile, be convenient for promote.The fixator collection is fixed, abdominal cavity The functions such as injection, tail vein injection, acupuncture are in one.The device is applied widely, is applicable to big mouse fixation and uses.
For the ease of the rat after fixation is injected intraperitoneally, the position that the fixed middle part of bottom plate 1 keeps left is provided with Through the intraperitoneal injection hole 8 of its thickness direction, intraperitoneal injection hole 8 is located at the right side of steady stern post 6.
In order that the fixator can be adapted to various sizes of rat, to increase the versatility of the fixator, in addition to it is vertical Ground is fixedly installed on the regulation stud 9 on fixed bottom plate 1, and the regulation stud 9 is located at the fixed middle part of bottom plate 1 and close to fixed net Nut is equipped with the position of 2 rear ends edge, regulation stud 9, nut is preferably wing nut, it is so convenient that fixed net 2 is carried out Push.
In order to improve injection precision, the intraperitoneal injection hole 8 is obliquely set from left to right from top to bottom, its angle of inclination For 45 degree.
In order to increase the stationarity of fixed bottom plate 1, meanwhile, also for can more easily take the fixator, the fixation The lower surface outer rim of bottom plate 1 is provided with multiple bearings 10.
As a preferred embodiment, the cross section of the fixed bottom plate 1 is rectangular.
As a preferred embodiment, the vertical section of the barrier plate 5 is the low circular arc in the high two ends in middle part.
In order to improve the effect of fixed rat heel portion, two elastic webbings 7 are located at two steady fore-and-aft directions of stern post 6 respectively Outside.
In order to can guarantee that experiment effect, and the gross weight of fixator can be reduced, the fixed bottom plate 1 and barrier plate 5 are equal It is made up of hard plastic board.
In use, barrier plate 5 is kept right placement, opening is removed into the front end of fixed net 2 along from hook 4.The right hand is caught Rat, belly is pressed close to fixed bottom plate 1 and is positioned on fixed bottom plate 1, and its afterbody is clipped between two steady stern posts 6, now rat to Before crawl into.Left hand is rapid to cover rat back by fixed net 2, and itself and hook 4 are engaged while pressing fixed net 2.If rat Volume is too small, and the nut of the fixed net 2 of pressing can be equipped with the upper end of regulation stud 9, makes the volume for fixing net 2 reduce to push down mouse Back.Rat-tail is gently drawn with hand, heel portion is pulled out successively in the fixed rear portion of net 2, two foot is respectively placed in two steady stern posts 6 Outside, and filled in elastic webbing 7, and fasten elastic webbing 7, note the tightness of elastic webbing 7, both only pine caused foot Portion is shaken off, and is unlikely to tightly to influence very much pedal blood circulation again.After experiment terminates, untie elastic webbing 7 and unclamp foot.The right hand is carried greatly Rat-tail portion, left hand presses lightly on fixed net 2, and it is lifted from hook 4, now can remove rat completely.

Claims (9)

1. a kind of rat fixator, including fixed bottom plate (1), it is characterised in that also including fixed net (2), the fixed net (2) Middle part curvedly bent to away from fixed bottom plate (1) direction, the rear end of fixed net (2) is along with being fixedly installed on fixed bottom plate (1) hinge ring (3) of upper surface posterior edges is hinged, the quantity at least two of the hinge ring (3), on the fixed bottom plate (1) Surface forward edge, which is fixed with least two, is used for the hook (4) that twisting fixes net (2) front end edge, fixed bottom plate (1) upper table The barrier plate (5) of fore-and-aft direction stretching, extension is fixedly installed in the middle part of right side of face, fixed bottom plate (1) upper surface left side central portion is abreast solid Surely two steady stern posts (6) are provided with, two steady stern post (6) left parts are provided with two elastic webbings (7).
2. a kind of rat fixator according to claim 1, it is characterised in that kept left in the middle part of the fixed bottom plate (1) Position is provided through the intraperitoneal injection hole (8) of its thickness direction, and intraperitoneal injection hole (8) is located at the right side of steady stern post (6).
3. a kind of rat fixator according to claim 2, it is characterised in that also including being vertically fixedly installed on fixation Regulation stud (9) on bottom plate (1), the regulation stud (9) is located in the middle part of fixed bottom plate (1) and close to fixed net (2) rear end The position on edge, regulation stud is equipped with nut on (9).
4. a kind of rat fixator according to claim 3, it is characterised in that the intraperitoneal injection hole (8) is from top to bottom Obliquely set from left to right, its angle of inclination is 45 degree.
5. a kind of rat fixator according to any one of Claims 1-4, it is characterised in that the fixed bottom plate (1) Lower surface outer rim is provided with multiple bearings (10).
6. a kind of rat fixator according to claim 5, it is characterised in that the cross section of the fixed bottom plate (1) is in Rectangle.
7. a kind of rat fixator according to claim 6, it is characterised in that during the vertical section of the barrier plate (5) is The low circular arc in the high two ends in portion.
8. a kind of rat fixator according to claim 7, it is characterised in that two elastic webbings (7) are located at two respectively The outside of steady stern post (6) fore-and-aft direction.
9. a kind of rat fixator according to claim 8, it is characterised in that the fixed bottom plate (1) and barrier plate (5) It is made by hard plastic board.
CN201621271107.0U 2016-11-24 2016-11-24 Rat fixator Expired - Fee Related CN206508065U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621271107.0U CN206508065U (en) 2016-11-24 2016-11-24 Rat fixator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621271107.0U CN206508065U (en) 2016-11-24 2016-11-24 Rat fixator

Publications (1)

Publication Number Publication Date
CN206508065U true CN206508065U (en) 2017-09-22

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CN201621271107.0U Expired - Fee Related CN206508065U (en) 2016-11-24 2016-11-24 Rat fixator

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106539629A (en) * 2016-11-24 2017-03-29 徐州医科大学 A kind of rat fixator
CN109771083A (en) * 2019-03-28 2019-05-21 福建农林大学金山学院 The method for realizing subplantar injection using knee jerk reflex
CN110522531A (en) * 2019-09-03 2019-12-03 河南中医药大学 A kind of retaining frame device of Brain Radiation Injury model mice experiment

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106539629A (en) * 2016-11-24 2017-03-29 徐州医科大学 A kind of rat fixator
CN109771083A (en) * 2019-03-28 2019-05-21 福建农林大学金山学院 The method for realizing subplantar injection using knee jerk reflex
CN110522531A (en) * 2019-09-03 2019-12-03 河南中医药大学 A kind of retaining frame device of Brain Radiation Injury model mice experiment
CN110522531B (en) * 2019-09-03 2022-03-25 河南中医药大学 Protective frame device for radioactive brain injury model mouse experiment

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20170922

Termination date: 20191124