CN206393884U - Small-caliber tissue engineered blood vessels stand tube embryo preparation facilities - Google Patents
Small-caliber tissue engineered blood vessels stand tube embryo preparation facilities Download PDFInfo
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- CN206393884U CN206393884U CN201621266954.8U CN201621266954U CN206393884U CN 206393884 U CN206393884 U CN 206393884U CN 201621266954 U CN201621266954 U CN 201621266954U CN 206393884 U CN206393884 U CN 206393884U
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- discharging
- discharge controller
- adaptive
- mandrel
- standardization
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Abstract
The utility model discloses a kind of small-caliber tissue engineered blood vessels stand tube embryo preparation facilities, includes discharging control assembly, forced feed component, electric machine assembly and multifunctional groups holder assembly；The discharging control assembly includes adaptive discharge controller and discharging adjusting rod, and the discharging opening of discharging adjusting rod and adaptive discharge controller coordinates, by adjusting discharging adjusting rod position control pipe embryo length；Described electric machine assembly includes motor, standardization mandrel and electric machine control system, and standardization mandrel is fast changeable part, the internal diameter of its diameter control pipe embryo sample；The multifunctional groups holder assembly includes pedestal, material recycle disk and automatic adjusument support；Described adaptive discharge controller is fixed on the sliding bar of automatic adjusument support, by adjusting the distance between the position adjustments discharging opening of adaptive discharge controller and standardization mandrel with the wall thickness of control pipe embryo；By adjusting the distance relation of each inter-module, the pipe embryo sample of parameter preset is shaped.
Description
Technical field
The utility model is related to a kind of blood vessel embryo technology of preparing of scaffold for vascular tissue engineering, it is more particularly to automanual can
The intravascular stent pipe embryo preparation facilities of standardization mandrel, adjustable wall thickness and discharging opening length is replaced, belongs to medical device technology neck
Domain, it can also be used to the preparation of other field small-caliber tubular product.
Background technology
Scaffold for vascular tissue engineering implantation technique is just progressively being applied to the treatment of angiocardiopathy, will turn into treatment cardiovascular
One of essential therapeutic arsenals of disease, because intravascular stent needs to be implanted into human body so that proposed to scaffold for vascular tissue engineering
High requirement, wherein intravascular stent need to meet high cell density, small cells size, the connection of high abscess in terms of morphosis
Property etc. property, to ensure that the nutrition transport that histocyte grows in support is discharged with metabolin.Batch (-type) fretting map technology
It is widely used in the theoretical research of foam structure morphology.In the shadow using the technical research intravascular stent inner cell morphosis
Firstly the need of sample is prepared during the factor of sound, for the preparation of hollow pipe embryo, it usually needs expensive extruder or note
Molding machine, and extrusion neck ring mold or injection mold are needed, according to the scheme of parameter one mould of correspondence, then need to prepare largely
The pipe in different inside and outside footpaths, rod mould are, it is necessary to expend substantial amounts of manpower, resource, time.The utility model provides a kind of semi-automatic
Replaceable standardization mandrel, the adjustment height changed（Regulation pipe germ wall is thick）Prepare and fill with the intravascular stent pipe embryo of discharging opening length
Put, in the preparation process of scaffold for vascular tissue engineering pipe embryo, be greatly saved manpower, time, while greatly reducing manufacture
Cost.
The content of the invention
In order to accelerate the preparation of intravascular stent pipe embryo sample, manufacturing cost is reduced, the utility model discloses a kind of osculum
Footpath scaffold for vascular tissue engineering pipe embryo preparation facilities, the small-caliber tissue engineered blood vessels stand tube embryo preparation facilities, includes discharging
Control assembly, forced feed component, electric machine assembly and multifunctional groups holder assembly；The discharging control assembly includes adaptive discharging
Controller and discharging adjusting rod, the discharging opening of discharging adjusting rod and adaptive discharge controller coordinate, by adjusting discharging regulation
The position adjustments of bar discharge length with control pipe embryo length；Described electric machine assembly includes motor, standardization mandrel and motor
Control system, standardization mandrel is fast changeable part, the internal diameter of its diameter control pipe embryo sample；Described multi-functional base
Component includes pedestal, material recycle disk and automatic adjusument support；Described adaptive discharge controller is fixed on adaptive tune
On the sliding bar for saving support, adaptively gone out by adjusting position adjustments of the adaptive discharge controller on automatic adjusument support
Expect the distance between controller outlet and standardization mandrel with the wall thickness of control pipe embryo；By adjusting the distance relation of each inter-module,
Pipe embryo length, internal diameter, the quick control of wall thickness are realized, material is coated on the standardization mandrel of rotation, parameter preset is shaped
Pipe embryo sample.The pipe embryo preparation facilities can be applied to medicine equipment and other field, for preparing small-caliber tubular product, should
Material includes all kinds of polymer and other big viscosity, solidifies slower material.The preparation facilities use technical scheme be：
When preparing the intravascular stent pipe embryo sample of different inner diameters, length, wall thickness, the cubical contraction of material is calculated, it is determined that preparing
After the dimensional parameters that setting is needed during pipe embryo, pass through and change standardization mandrel, mobile discharging adjusting rod, regulation sliding bar and determine
Parameter correspondence, so as to obtain pre-set dimension parameter intravascular stent pipe embryo internal diameter, length, the intravascular stent pipe embryo of wall thickness.Technical side
Case detailed process is as follows：
The small-caliber vascular stent pipe embryo preparation facilities contains discharging control assembly（Fig. 6）, electric machine assembly（Fig. 2）, it is many
Function base assembly（Fig. 3, Fig. 4）With forced feed component（Fig. 5）.Wherein, the control assembly that discharges is comprising discharging adjusting rod and certainly
Discharge controller is adapted to, for adaptive discharge controller, its cross section is sector, and the cross sectional shape is more conducive to material stream
To adaptive discharge controller discharging opening, there are two circular opens its top, and centre opening is material charging aperture, passes through rubber
Pipe is connected with forced feed component, and the opening of close one end is exhaust outlet, is below rectangle discharging opening, makes material from adaptive
Outflow in discharge controller is answered to be coated on standardization mandrel, wherein, adaptive discharge controller is fixed on automatic adjusument branch
On the sliding bar of frame, discharging adjusting rod is engaged with the discharging opening of adaptive discharge controller, by adjusting discharging adjusting rod
Position can change adaptive discharge controller discharging opening length, so that control pipe embryo length；Electric machine assembly contains motor, mark
Standardization mandrel and electric machine control system, wherein standardization mandrel is fast changeable part, in control pipe embryo sample
Footpath, multifunctional groups holder assembly includes pedestal, material recycle disk, automatic adjusument support, and material recycle disk is to reclaim standardization
The unnecessary material flowed down on mandrel, automatic adjusument support includes sliding bar, chute with a scale, cast support fixing groove, wherein,
Sliding bar is cooperated with chute with a scale, and adaptive discharging is adjusted by adjusting position of the sliding bar in chute with a scale
Vertical range between controller discharging opening and motor standard mandrel, realizes the regulation of pipe embryo sample wall thickness；Forced feed group
Part comprising pressurization funnel, cast support, rubber tube, piston push rod, rubber tube to connect pressure-applying unit with discharging control assembly,
Piston push rod makes material rapidly enter in adaptive discharge controller, realizes that discharge velocity is adjusted, it is ensured that adaptive discharging control
Material flows out from discharging opening in device.The equipment of whole intravascular stent pipe embryo preparation facilities is simple with process, reduces and sets
Standby investment with it is time-consuming, meanwhile, material recycle disk is placed with pedestal, the waste of material is reduced, reduces manufacturing cost,
Form a kind of energy-conserving and environment-protective, efficient intravascular stent pipe embryo preparation system.
The characteristics of technical solutions of the utility model is：
1. low cost development
The intravascular stent pipe embryo preparation facilities is low for equipment requirements, discharging control assembly, multifunctional groups holder assembly, pressurize into
Expect component, each component processing of electric machine assembly is simple, and each component of the preparation facilities is reusable, greatly reduces and sets
Standby manufacturing cost, while being provided with material recycle disk in the multifunctional groups holder assembly, can make material obtain nearly 100% utilization；
2. technology is easily realized
The pipe embryo preparation facilities mainly make use of the bonding force active force that the center of circle is pointed between material and standardization mandrel, make
Material is obtained to move in a circle with standardization mandrel.Fluid foods with larger viscosity turn with standardization mandrel in identical speed
When dynamic, it is coated uniformly on standardization mandrel, control rotating speed makes material not splashed with standardization mandrel rotation, when material is solid
Motor is closed after change, after mandrel to be normalized stops operating, you can obtain pre-set dimension parameter and pipe embryo shape in uniform thickness is tried
Sample；
3. diversification is controlled
When preparing the pipe embryo sample of preliminary dimension, drawn according to the cubical contraction of material in preparation process in pipe embryo
Footpath, length, three parameters of wall thickness, the internal diameter of intravascular stent pipe embryo is adjusted by changing standardization mandrel；Sliding bar is adjusted, is used
To determine the vertical range between adaptive discharge controller discharging opening and standardization mandrel；Discharging adjusting rod is moved to control out
The discharging length of material mouth.Regulate after size, using pressue device, in the presence of piston push rod, it is ensured that material can be from adaptive
Answer in the discharging opening in discharge controller and flow out, big viscosity fluid is flowed out coating from the discharging opening of adaptive discharge controller
Onto standardization mandrel, so as to obtain the pipe embryo sample of pre-set dimension；
4. it is semi-automatic
Process, only need to regulate the dimensional parameters of intravascular stent pipe embryo preparation facilities according to pipe embryo size, in pressurization
In the presence of device, material is set to be turned to standardization mandrel after material solidification, target tube embryo sample can be obtained by closing motor.
There is presently no one standardization intravascular stent pipe embryo technology of preparing, and with existing simple pipe embryo technology of preparing
Compare, it is of the present utility model to be beneficial in that when preparing small-bore pipe embryo sample using big viscosity fluid, it is not necessary to big
Equipment investment, the equipment required for the preparation facilities is simple, reusable, and the assembly relation of inter-module is easy, and each group
The manufacturing cost of part is low, and the process of the pipe embryo preparation facilities is simple, and manufacture efficiency is high, can be quick by appropriate regulation
The intravascular stent pipe embryo sample of target size parameter is obtained, meanwhile, the preparation facilities is additionally provided with material recycle disk, can greatly carry
The utilization rate of high material, is conducive to energy-conserving and environment-protective；Various sizes of blood vessel can be obtained by the correlation between adjusting part
Stand tube embryo sample.
Brief description of the drawings
Below in conjunction with accompanying drawing, the utility model is described in detail：
Fig. 1 is the general assembly drawing of pipe embryo preparation facilities；
Fig. 2 is electric machine assembly figure；
Fig. 3 is multifunctional groups holder assembly stereogram；
Fig. 4 is multi-functional base component side view；
Fig. 5 is forced feed component drawings；
Fig. 6 is discharging control assembly figure：
Reference：1- pedestals；2- motors and electric machine control system；3- standardizes mandrel；The adaptive discharge controllers of 4-；
5- automatic adjusument supports；6- material recycle disks；7- cast supports；8- rubber tubes；9- nuts；10- sliding bars；11- scales are slided
Groove；12- cast support fixing grooves；13- motors fix guide pillar；14- pressurization funnels；15- vent caps；16- adaptively discharges control
Device charging aperture processed；The adaptive discharge controller exhaust outlets of 17-；18- discharging adjusting rods；The adaptive discharge controller fixing grooves of 19-；
The adaptive discharge controller discharging openings of 20-；21- piston push rods.
Embodiment
As it was previously stated, the utility model prepares various sizes of small-caliber tissue engineered blood vessels support for big viscosity fluid
A kind of pipe embryo, it is proposed that small-caliber tissue engineered blood vessels stand tube embryo preparation facilities, is described below in detail described in the utility model
Pipe embryo preparation facilities specific implementation process.
Before using the intravascular stent pipe embryo preparation facilities, it is necessary first to which the cubical contraction cooled down according to material is determined
Three major parameters of internal diameter, length, wall thickness of scaffold for vascular tissue engineering pipe embryo, then choose the standardization of correspondence internal diameter size
Mandrel 3 is assembled on motor, adjusts sliding bar 10, makes hanging down between the discharging opening of adaptive discharge controller and standardization mandrel
Straight distance is consistent with the wall thickness parameter of pipe embryo sample, meanwhile, mobile discharging adjusting rod 18 is closed in adaptive discharge controller
Discharging opening, and open the exhaust cap 15 in adaptive discharge controller.
By the big viscosity fluid prepared（Such as PCL）It is passed into adaptive discharge controller, goes out until adaptively through funnel
Expect that material in controller is full to after exhaust outlet, close exhaust outlet, continue injecting material into pressurization funnel, in funnel to be pressurised
Material when will be full, stop injecting material, piston push rod be satisfied with pressurization funnel.
Demoulding processing is carried out on standardization mandrel, motor is opened, rotating speed, steering according to needed for the property and sample of sample
Deng requirement, regulation motor control system makes motor be run under Parameter Conditions needed for sample, then moves discharging adjusting rod, makes
The discharging length of discharging opening 20 under adaptive discharge controller is consistent with the length parameter of pipe embryo sample, determines that discharging opening is beaten
After opening, the piston push rod on pressurization funnel is promoted, material flow direction under piston push rod effect is standardized mandrel and is coated in mark
On standardization mandrel, and rotated with standardization mandrel, while the material dropped from standardization mandrel is by material recycle disk institute
Store.
The tangential velocity of material is kept and tangent one section of discharging opening in adaptive discharge controller on mandrel 3 to be normalized
Time so that the shape of pipe embryo sample shaped on standardization mandrel keep stablizing it is indeformable after, mobile discharging adjusting rod is closed
Discharging opening in adaptive discharge controller, and keep motor to continue to run with.
Close discharging opening after, treat material with standardization mandrel operation certain time, observation rotating shaft on pipe embryo sample whether
Solidification, if uncured, regulation motor control system keeps motor to continue to run with, if solidification is completed, now closes motor, takes
Standardization mandrel on lower motor, and skid off pipe embryo, you can obtain target tube embryo sample.
It the foregoing is only of the present utility model and specifically apply example, it is all new in this practicality not to limit the utility model
Within the spirit and principle of type, any modification, equivalent substitution and improvements made etc. should be included in protection of the present utility model
Within the scope of.
Claims (4)
1. small-caliber tissue engineered blood vessels stand tube embryo preparation facilities, includes discharging control assembly, forced feed component, group of motors
Part and multifunctional groups holder assembly；The discharging control assembly includes adaptive discharge controller and discharging adjusting rod, discharging regulation
Bar and the discharging opening of adaptive discharge controller coordinate, and length is discharged with control pipe by adjusting the position adjustments of discharging adjusting rod
Embryo length；Described electric machine assembly includes motor, standardization mandrel and electric machine control system, and standardization mandrel is can quickly more
Part is changed, the internal diameter of its diameter control pipe embryo sample；Described multifunctional groups holder assembly include pedestal, material recycle disk with it is adaptive
Answer adjusting bracket；Described adaptive discharge controller is fixed on the sliding bar of automatic adjusument support, adaptive by adjusting
Answer between the adaptive discharge controller outlet of position adjustments of the discharge controller on automatic adjusument support and standardization mandrel
Distance is with the wall thickness of control pipe embryo；By adjusting the distance relation of each inter-module, realize pipe embryo length, internal diameter, wall thickness it is quick
Control, makes material be coated on the standardization mandrel of rotation, shapes the pipe embryo sample of parameter preset.
2. small-caliber tissue engineered blood vessels stand tube embryo preparation facilities according to claim 1, it is characterised in that：It is described from
Adapt to there are two circular opens above discharge controller, the wherein opening of centre is charging aperture, and guide sleeve is passed through with rubber tube
It is connected, the opening close to one end is for rectangle discharging opening, adaptive discharging control below exhaust outlet, adaptive discharge controller
The cross section of device is designed as sector, and fan-shaped angle face is more conducive to flow direction of material discharging opening；The discharging adjusting rod with it is adaptive
Rectangle discharging opening below discharge controller is engaged, and the discharging of rectangle discharging opening is controlled by mobile discharging adjusting rod
Length, predetermined length material is coated on standardization mandrel.
3. small-caliber tissue engineered blood vessels stand tube embryo preparation facilities according to claim 1, it is characterised in that：It is described from
Adapt to adjusting bracket and include sliding bar, chute with a scale, adaptively gone out by position adjustments of the mobile sliding bar in chute
The vertical range between the discharging opening and motor standard mandrel of controller is expected, with the wall thickness of regulation pipe embryo sample.
4. small-caliber tissue engineered blood vessels stand tube embryo preparation facilities according to claim 1, it is characterised in that：Described
Forced feed component includes pressurization funnel, cast support, rubber tube, piston push rod, and material is rapidly entered by piston push rod
Adaptive discharge controller and discharge adjustable speed, it is ensured that material flows out from discharging opening in adaptive discharge controller.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621266954.8U CN206393884U (en) | 2016-11-24 | 2016-11-24 | Small-caliber tissue engineered blood vessels stand tube embryo preparation facilities |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621266954.8U CN206393884U (en) | 2016-11-24 | 2016-11-24 | Small-caliber tissue engineered blood vessels stand tube embryo preparation facilities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206393884U true CN206393884U (en) | 2017-08-11 |
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ID=59509278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621266954.8U Expired - Fee Related CN206393884U (en) | 2016-11-24 | 2016-11-24 | Small-caliber tissue engineered blood vessels stand tube embryo preparation facilities |
Country Status (1)
| Country | Link |
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| CN (1) | CN206393884U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106393533A (en) * | 2016-11-24 | 2017-02-15 | 郑州大学 | Device for preparing minor-caliber tube blank of tissue engineering vascular stent |
-
2016
- 2016-11-24 CN CN201621266954.8U patent/CN206393884U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106393533A (en) * | 2016-11-24 | 2017-02-15 | 郑州大学 | Device for preparing minor-caliber tube blank of tissue engineering vascular stent |
| CN106393533B (en) * | 2016-11-24 | 2018-07-17 | 郑州大学 | Small-caliber tissue engineered blood vessels stand tube embryo preparation facilities |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170811 Termination date: 20181124 |
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| CF01 | Termination of patent right due to non-payment of annual fee |