CN206303938U - A kind of left ventricle reconstructing device for medical treatment - Google Patents
A kind of left ventricle reconstructing device for medical treatment Download PDFInfo
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- CN206303938U CN206303938U CN201621072178.8U CN201621072178U CN206303938U CN 206303938 U CN206303938 U CN 206303938U CN 201621072178 U CN201621072178 U CN 201621072178U CN 206303938 U CN206303938 U CN 206303938U
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- left ventricle
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Abstract
The utility model is related to a kind of left ventricle reconstructing device for medical treatment, and it includes support frame, the polymeric membrane being arranged on inside and outside support frame and is coated in the anti-leakage in inner side and the medication coat of anticoagulation of the barrier layer that polymeric membrane outer surface can strengthen polymeric membrane formation.The utility model is by being coated in the medication coat of polymeric membrane outer surface, so as to strengthen the anti-leakage in inner side and the anticoagulant effect of the barrier layer of polymeric membrane formation, the further heart function for improving remodeling ventricle and recovering patient, have important practical significance and good potential applicability in clinical practice, simultaneously, it is easy to implement, and low cost.
Description
Technical field
The utility model belongs to medical instruments field, and in particular to a kind of left ventricle reconstructing device for medical treatment.
Background technology
Heart failure, as one of morbidity and dead primary inducement, has become Chinese or global burden.Suffer from
The five year survival rate of person is similar with breast cancer.Although the large area popularization of present calcification score technology, still there is 20% ~ 50%
Myocardial infarction patient can switch to heart failure patient, and left ventricle geometry is used as one of the main prognosis of heart failure, special
It is not that myocardial ischemia can change heart geometry.Especially it is easiest to myocardial infarction occur in three coronary arteries with descending anterior branch, ties
, there is apex impaired movement even aneurysm in antetheca large area infarct caused by fruit, further aggravates remodeling ventricle and appearance
CHF symptom.Neurohormone treats the limitation with reversal of heart failure, the left ventricle volume reduction mental and physical efforts based on apparatus
Exhaustion therapy causes extensive clinical concern.Earliest left ventricle capacity-reduction device by Branislav Radovencevic and
Serjan Nikolic attempt being implanted in cow body in 1999.Left ventricle reconstructing device is unique minimal invasion implantation
Left ventricle capacity-reduction device.The operation that the device is implanted into so as to reach improvement chronic heart failure symptom is referred to as percutaneous Left Ventricular Remodeling
Art（Percutaneous ventricular restoration, PVR）.
Left ventricle shielding system is divided into approach system, 3 parts of induction system and left ventricle reconstructing device.Approach system
It is made up of 14 F or 16 F guiding catheters and expander, main purpose is to set up the path up to left ventricle apex.Delivery conduit
The left ventricle reconstructing device that offer is connected with torque axis reaches the passage of apex, and moment of torsion shaft end has a knob and left ventricle weight
Device and airbags are built, the near-end of conduit has release knob.
8 kinds of left ventricle reconstructing devices of specification are had at present, and the maximum gauge of device is respectively 50-120 after expanding completely
Mm, every kind of diameter is divided into pin long with the major axis of device again（standard）With short pin（short）Two kinds.Left ventricle reconstructing device
Be it is currently the only can be by the left ventricle capacity-reduction device of the minimally invasive implantation of conduit, multiple American-European large-scale multicenter clinical trials are equal
Confirmed security and validity.The left ventricle capacity-reduction device for needing surgical operation to be implanted into relative to other four kinds, left ventricle weight
Build device as can the device of minimally invasive implantation have its advantage, more selections can be provided for more endstage cardiac insufficiency patients.
Left ventricle reconstructing device monnolithic case generally comprises support frame, the macromolecule being overlying on outside support frame like parachute-like
Barrier film, the anchor for fixing device, the base that the apex of the heart can be protected not to be damaged is contacted with the apex of the heart positioned at support frame end.Support
Frame further includes multiple umbrella frame shape poles and multiple cambered surfaces, wherein connecting structure by cambered surface per two adjacent umbrella frame shape poles
Into the support frame for being inverted umbrella shape.Anchor is connected to the outer end of umbrella frame shape pole.The main material of macromolecule barrier film is polytetrafluoro
Vinyl film（ePTEF）, it is also possible to other macromolecular materials, its Main Function is to prevent blood from flowing into the apex of the heart, plays the work of closure
With.However, only relying on this polymeric membrane to be intercepted, anti-leakage and anticoagulant effect are undesirable.Additionally, in the prior art, branch
Support and the usual split of base are set, and are connected through a screw thread, rivet or are welded together, and whole device is being processed and used
During stability and reliability cannot be guaranteed.
The content of the invention
It is to overcome the deficiencies in the prior art that the utility model to be solved technical problem, there is provided a kind of anti-leakage and anticoagulant effect
The good left ventricle reconstructing device for medical treatment.
To solve above technical problem, the utility model is adopted the following technical scheme that：
A kind of left ventricle reconstructing device, it includes support frame, base, the polymeric membrane on support frame as described above and receipts
Rope is put, described support frame includes multiple umbrella frame shape poles, the fixed anchor for fixing device, particularly, the described left heart
Room reconstructing device also includes that being coated in the polymeric membrane surface has the coating of anti-leakage and/or anticoagulation.
Preferably, the coating is medication coat.It is further preferred that described medication coat is anti-proliferative drugs coating
Or/and antithrombotic reagent coating.Specifically, anti-proliferative drugs can be rapamycin, taxol, arsenic trioxide, ABT-
578th, Ai Luomosi or macrolide antibiotics.Antithrombotic reagent can be closed for Phosphorylcholine, heparin, carbide or silicon charcoal
Gold.
Preferably, the base includes multiple arcs bottom bar of the opening towards support frame, and the multiple arc bottom bar is common
The supporting plane that formation is contacted with the apex of the heart, the umbrella frame shape pole is wholely set with the arc bottom bar.
According to one of the present utility model specific and preferred aspect, the arc described in umbrella frame shape pole and whole described in whole
Shape bottom bar is wholely set, and is made up through laser cutting of a Nitinol pipe.Further, a Nitinol pipe from
One end is in turn divided into first segment, second section and Section three to the other end, and the length of first segment is most long, and it is through being cut by laser shape
Into the multiple umbrella frame shape pole；Section three, length is placed in the middle, and it forms multiple arcs bottom bar through laser cutting；The length of second section
Degree is most short, its connecting portion for forming the multiple umbrella frame shape pole and many arc bottom bars.Preferably, the Nitinol
The external diameter of pipe is 2 ~ 6mm, and wall thickness is 0.1 ~ 0.6mm.
According to another specific and preferred aspect of the present utility model, described base is formed by nitinol alloy wire braiding
It is solid netted.
According to an also specific aspect of the present utility model, base can be molded by macromolecular material.
Usually, the umbrella frame shape pole has 10 ~ 30, and circumference along umbrella shape is uniformly distributed, each umbrella frame shape
The width of pole is 0.1 ~ 0.6mm.
Preferably, the umbrella frame shape pole is in Y types or linear pattern.Wherein preferred Y types, take the stability of the form pole
And better reliability.According to a specific preferred aspect, the umbrella frame shape pole is in Y types, and it has first end and away from described
Two the second ends of first end, first end is connected anchor, the second end connect base.
Further, the polymeric membrane is covered（For example bonded by melt process）Inside and outside support frame, its
Main material is poly tetrafluoroethylene（ePTEF）, it is also possible to other macromolecular materials, thickness 0.01-0.20mm.Main Function is
Prevent blood from flowing into the apex of the heart, play a part of closure.Inner membrance is circle, and external mold can be circular or petal.
Further, the effect of fixed anchor is fixing device, after piercing cardiac muscle plays positioning action and prevents release
Device is shifted.
Further, the material of folding and unfolding rope can be general absorbable surgical thread, positioned at support frame hangnail lower section, ripple
Shape wave is punctured on polymeric membrane circumference, the umbrella frame shape pole of support frame can be connected together, and plays contraction and release drop
Fall the effect of umbrella.According to the utility model, whole left ventricle reconstructing device is in parachute-like, for discoid during nature, can
Realize shrinking and launch, primary diameters 50-120mm by rope.
Due to the utilization of above-mentioned technical proposal, the utility model has following advantages compared with prior art：
The utility model is by being coated in the medication coat of polymeric membrane outer surface, so as to strengthen the resistance of polymeric membrane formation
The anti-leakage in inner side of interlayer and anticoagulant effect, the further heart function for improving remodeling ventricle and recovering patient, show with important
Sincere adopted and good potential applicability in clinical practice, meanwhile, the utility model is easy to implement, and cost is relatively low.
Brief description of the drawings
Fig. 1 is the schematic front view of the left ventricle reconstructing device of embodiment 1（Broken section）；
Fig. 2 is the medication coat of embodiment 1 and the layer of structure schematic diagram of polymeric membrane；
Fig. 3 is the schematic top plan view of the left ventricle reconstructing device of embodiment 1（Broken section）；
Fig. 4 is the schematic front view of the left ventricle reconstructing device of embodiment 2；
Fig. 5 is the schematic diagram of the base of the left ventricle reconstructing device of embodiment 2；
Fig. 6 is the schematic front view of the left ventricle reconstructing device of embodiment 3；
Fig. 7 is the schematic diagram of the base of the left ventricle reconstructing device of embodiment 3；
Wherein：1st, support frame；10th, umbrella frame shape pole；11st, fixed anchor；12,12 ', 12 ' ', base；13rd, connecting portion；130、
Sleeve pipe；131st, locking bolt；2nd, polymeric membrane；20th, inner membrance；21st, adventitia；3rd, medication coat；4th, rope.
Specific embodiment
Come to be further elaborated the technical solution of the utility model with reference to the accompanying drawings and detailed description.
Embodiment 1
As shown in Fig. 1 and Fig. 2, left ventricle reconstructing device of the present utility model, it includes support frame 1 and base 12.The branch
Support 1 includes the umbrella frame shape pole 10 of multiple Y types, is arranged on each first end 101 of umbrella frame shape pole 10（Outer end）For being pierced into
The fixed anchor 11 of cardiac muscle, umbrella frame shape pole 10 also has two the second ends 102 away from first end 101（It is inner）, the second end 102
It is connected with base 12.Base 12 includes multiple arcs bottom bar 120 of the opening towards support frame 1, and the plurality of arc bottom bar 120 is common
The supporting plane that formation is contacted with the apex of the heart, umbrella frame shape pole 10 is wholely set with arc bottom bar 120.
Further, all of umbrella frame shape pole 10 and all of arc bottom bar 120 be all by an external diameter be 2 ~ 6mm,
Wall thickness is processed for the Nitinol pipe of 0.1 ~ 0.6mm, namely support frame 1 and the entirety of base 12 are wholely set.Specifically
Ground, first segment, second section and Section three, the length of first segment are in turn divided into by a Nitinol pipe from one end to the other end
Degree is most long, is carried out laser cutting and forms multiple umbrella frame shape poles 10；Section three, length is placed in the middle, by it through being cut by laser shape
Into multiple arcs bottom bar 120；The length of second section is most short, and it forms multiple umbrella frame shape poles 10 and Duo Gen arcs bottom bar 120
Connecting portion 13.
Or, can also so set：Described multiple umbrella frame shape poles 10 and multiple arcs bottom bar 120 are by many NiTis
B alloy wire and/pipe are made, and every nitinol alloy wire and/pipe are in turn divided into first paragraph, second segment to the other end from one end
With the 3rd section, the length of first paragraph is most long, and it forms a umbrella frame shape pole 10, and the 3rd section of length is placed in the middle, and it forms one
Arc bottom bar 120, the length of second segment is most short, its connecting portion 13 for forming Connectable umbrella bone-shaped pole and arc bottom bar；Support frame 1
It is made up of welding, riveting or cluster connection etc. at connecting portion 13 many nitinol alloy wires and/pipe with base.Bundle
Formula connection is tied up multiple connecting portions 13 are fixed together using sleeve pipe 130 and pin 131 for example.
Further, left ventricle reconstructing device also includes being arranged on the height that multiple umbrella frame shape poles 10 form pileated regions
Molecular film 2, polymeric membrane 2 includes being respectively arranged on the inner membrance 20 and adventitia 21 in outside in multiple umbrella frame shape poles 10, polymeric membrane 2
Main material be poly tetrafluoroethylene（ePTEF）, it is also possible to other macromolecular materials, it is bonded together by melt process,
Thickness 0.01-0.20mm.Main Function is to prevent blood from flowing into the apex of the heart, plays a part of closure.In inner membrance 20 and adventitia 21
Surface is respectively formed with the anti-leakage in inner side and the medication coat 3 of anticoagulation of the barrier layer that can strengthen polymeric membrane formation.Should
Medication coat 3 is anti-proliferative drugs or/and antithrombotic reagent.Specifically, anti-proliferative drugs are rapamycin, taxol, three oxygen
Change two arsenic, ABT-578, Ai Luomosi or macrolide antibiotics.Antithrombotic reagent can be Phosphorylcholine, heparin, charing
Thing or silicon charcoal alloy.
Further, left ventricle reconstructing device also includes connecting the end near fixed anchor 11 of each umbrella frame shape pole 10
The folding and unfolding rope 4 being connected together.Rope 4 has to be tightened up and unclamps two states, when in tightening state, multiple umbrella frame shape sections
Bar 10 inwardly draws in and sets；When in releasing orientation, multiple umbrella frame shape poles 10 are flared out setting.Specifically, rope 4 is
Absorbable surgical thread, and positioned at the lower section of fixed anchor 11, undulate is punctured and formed on circumference in polymeric membrane（Repeat from
After adventitia penetrates internal model, then passed to adventitia from internal model）, so as to support frame 1 is connected together, play what is shunk and unfurl an umbrella
Effect.Further, after rope 4 unclamps, a diameter of 50-120mm that the top of polymeric membrane 2 can be formed（Namely umbrella support is opened
Maximum gauge）.
In this example, fixed anchor 11 is turned up by the first end of umbrella frame shape pole 10 and is formed, and hangnail is formed with its point, its
It is more than 90 ° with turned out tip portion angle.At the same time it can also increase multiple developing apparatus, each hangnail can be observed and pierced
Enter the position of cardiac muscle, be practical operation provides convenient.
To sum up shown, the present embodiment has the advantage that：
1st, by being coated in the medication coat on polymeric membrane surface, so as to strengthen the inner side of the barrier layer of polymeric membrane formation
Anti- leakage and anticoagulant effect, the further cardiac function for improving remodeling ventricle and recovering patient；
2nd, the umbrella frame shape pole and base of support frame are formed by thermal finalization after laser cutting by an alloy pipe, this
Sample is conducive to the stability and reliability in product processing, and simple structure is easy to implement, and low cost；
3rd, polymeric membrane is bonded on support frame by melt process, effectively prevents blood from flowing into the apex of the heart, plays closure
Effect；
5th, by the setting of arc bottom bar so that each edge shape is mellow and full, the damage caused to human body is prevented；
6th, rope is absorbable surgical thread, is not only convenient for the expansion and gathering of support frame, and be easy to the operation of operation.
7th, support effect using the left ventricle reconstructing device of the present embodiment is good, accurate positioning, easy to operate, reduces the left heart
Room volume, reduce left ventricular tension so as to improve remodeling ventricle and recover patient heart function, have important practical significance and
Good potential applicability in clinical practice.
Embodiment 2
As shown in Figures 4 and 5, the present embodiment provides a kind of left ventricle reconstructing device, and in addition to base, remaining is with embodiment 1.This
In example, base 12 ' is set with support frame split, is fixed by sleeve pipe 130 and locking bolt 131 therebetween.Wherein base 12 ' is served as reasons
The cubic network shape of nitinol alloy wire braiding.
Embodiment 3
As shown in Figures 6 and 7, the present embodiment provides a kind of left ventricle reconstructing device, and in addition to base, remaining is with embodiment 1.This
In example, base 12 ' ' set with support frame split, fixed by sleeve pipe 130 and locking bolt 131 therebetween.Wherein base 12 ' ' be
It is molded by nylon Polymer material and is formed.
The utility model is described in detail above, the personage that this art is familiar with its object is to allow can be much of that
Solve content of the present utility model and be carried out, protection domain of the present utility model, and the utility model can not be limited with this
The above embodiments are not limited to, all equivalent change or modifications made according to Spirit Essence of the present utility model should all cover
Within protection domain of the present utility model.
Claims (10)
1. a kind of for medical left ventricle reconstructing device, it includes support frame, base, the macromolecule on support frame as described above
Film and folding and unfolding rope, described support frame include multiple umbrella frame shape poles, the fixed anchor for fixing device, and its feature exists
In：Described left ventricle reconstructing device is also including being coated in the polymeric membrane surface, with anti-leakage and/or the painting of anticoagulation
Layer.
2. according to claim 1 for medical left ventricle reconstructing device, it is characterised in that：The coating is applied for medicine
Layer.
3. according to claim 2 for medical left ventricle reconstructing device, it is characterised in that：Described medication coat is
Anti-proliferative drugs coating or/and antithrombotic reagent coating.
4. according to claim 3 for medical left ventricle reconstructing device, it is characterised in that：Described anti-proliferative drugs
It is rapamycin, taxol, arsenic trioxide, ABT-578, Ai Luomosi or macrolide antibiotics.
5. according to claim 3 for medical left ventricle reconstructing device, it is characterised in that：Described antithrombotic reagent
It is Phosphorylcholine, heparin, carbide or silicon charcoal alloy.
6. according to claim 1 for medical left ventricle reconstructing device, it is characterised in that：The base includes opening
Towards the multiple arcs bottom bar of support frame, the multiple arc bottom bar is collectively forming the supporting plane contacted with the apex of the heart, the umbrella
Bone-shaped pole is wholely set with the arc bottom bar.
7. according to claim 6 for medical left ventricle reconstructing device, it is characterised in that：Umbrella frame shape described in whole
Pole is wholely set with the arc bottom bar described in whole, and is made up through laser cutting of a Nitinol pipe.
8. according to claim 1 for medical left ventricle reconstructing device, it is characterised in that：Described base is by nickel
It is solid netted that titanium alloy wire weaves；Or, base is molded by macromolecular material.
9. according to claim 1 for medical left ventricle reconstructing device, it is characterised in that：The polymeric membrane includes
The inner membrance and adventitia for preventing blood from flowing into the apex of the heart are bonded in inside and outside each described umbrella frame shape pole and are formed, then it is described
The surface of inner membrance and adventitia is equipped with the coating.
10. according to claim 1 for medical left ventricle reconstructing device, it is characterised in that：The fixed anchor is located at
The umbrella frame shape pole outer end, it has the fixed point of the multiple that can be pierced into cardiac muscle, and the multiple fixed point is by fixed anchor remote
Side bifurcated from the umbrella frame shape pole is formed.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621072178.8U CN206303938U (en) | 2016-09-22 | 2016-09-22 | A kind of left ventricle reconstructing device for medical treatment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621072178.8U CN206303938U (en) | 2016-09-22 | 2016-09-22 | A kind of left ventricle reconstructing device for medical treatment |
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| Publication Number | Publication Date |
|---|---|
| CN206303938U true CN206303938U (en) | 2017-07-07 |
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|---|---|---|---|
| CN201621072178.8U Active CN206303938U (en) | 2016-09-22 | 2016-09-22 | A kind of left ventricle reconstructing device for medical treatment |
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| CN (1) | CN206303938U (en) |
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