CN206292212U - High performance liquid chromatograph - Google Patents
High performance liquid chromatograph Download PDFInfo
- Publication number
- CN206292212U CN206292212U CN201621400957.6U CN201621400957U CN206292212U CN 206292212 U CN206292212 U CN 206292212U CN 201621400957 U CN201621400957 U CN 201621400957U CN 206292212 U CN206292212 U CN 206292212U
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- Prior art keywords
- flow cell
- high performance
- blender
- solvent reservoir
- performance liquid
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Abstract
The utility model discloses a kind of high performance liquid chromatograph, it includes aqueous solvent reservoir, organic solvent reservoir and blender；Blender is connected with high-pressure pump, and automatic sampler is provided between high-pressure pump and chromatographic column, and chromatographic column is located in insulating box；Chromatographic column is connected by liquid pushing tube with detector；Insulating box includes casing, cylinder and temperature regulation section, and temperature regulation section includes being arranged on heating rod of the cabinet wall in roundabout shape by connector, and circulating fan is provided with the cavity formed between heating rod and casing；The side of cylinder is provided with temperature sensor, and temperature sensor is electrically connected with circulating fan and heating rod；Liquid pushing tube includes sleeve pipe and connecting tube, and air layer and spongy layer are disposed between connecting tube and sleeve pipe, and sleeve outer wall is provided with a thermal insulation layer；Detector includes temperature adjustment block, the flow cell in temperature adjustment block, the light source portion above flow cell and the optical-electrical converter below flow cell, and flow cell is connected with connecting tube.
Description
Technical field
The utility model is specifically related to a kind of high performance liquid chromatograph.
Background technology
Existing liquid chromatograph is main by reservoir, blender, high-pressure pump, injector, chromatographic column, detector and record
Instrument is constituted.Mobile phase in reservoir squeezes into system by blender by high-pressure pump, and sample solution enters system stream through injector
Road, is loaded into chromatographic column by mobile phase, because each component in sample solution has difference in translational speed, is separated into single
Component flows out from post successively, and during by detector, sample concentration is converted into electric signal and is sent to recorder, and data are with collection of illustrative plates
Form is printed, and mobile phase is discharged by the output port of detector；At present, there is essence in liquid chromatograph of the prior art
Density and the more low defect of reliability.
Utility model content
The purpose of this utility model is to provide a kind of precision and reliability high performance liquid chromatograph higher.
In order to solve the above technical problems, the utility model provides a kind of high performance liquid chromatograph, it includes aqueous solvent liquid storage
Device, organic solvent reservoir and blender, are connected with the first degassing unit, organic solvent between aqueous solvent reservoir and blender
The second degassing unit is connected between reservoir and blender；Blender is connected with high-pressure pump, is set between high-pressure pump and chromatographic column
Automatic sampler is equipped with, chromatographic column is located in insulating box；
Chromatographic column is connected by liquid pushing tube with detector, and detector is electrically connected with recorder；Insulating box includes casing, is located at
Cylinder and the temperature regulation section for being symmetrically mounted on casing surrounding in casing, temperature regulation section include being arranged on case by connector
Internal wall is provided with circulating fan in the heating rod of roundabout shape in the cavity formed between heating rod and casing；The side of cylinder
Temperature sensor is provided with, temperature sensor is electrically connected with circulating fan and heating rod；
Liquid pushing tube include sleeve pipe and the connecting tube in sleeve pipe, be disposed between connecting tube and sleeve pipe air layer and
Spongy layer, sleeve outer wall is provided with a thermal insulation layer；Detector include temperature adjustment block, the flow cell in temperature adjustment block,
Light source portion above flow cell and the optical-electrical converter below flow cell, flow cell are connected with connecting tube.
Further, the lower end in light source portion is provided with diaphragm and concentrator, and concentrator is located at the lower end of diaphragm.
Further, condenser is aspherical condenser.
Further, the first valve, organic solvent reservoir are connected between aqueous solvent reservoir and the first degassing unit
The second valve is connected between the second degassing unit.
Further, light source portion is deuterium lamp.
The beneficial effects of the utility model are：The high performance liquid chromatograph is water-soluble by the first valve and the second valve regulated
Agent and the blending ratio of organic solvent, and degassing process has been carried out to aqueous solvent and organic solvent before combination, and by following
The reasonable design of ring blower fan and heating rod and arrangement, make temperature adjustment process more uniformly with fully, improve the precision of detection
And reliability；Meanwhile, the temperature of connecting tube is not easily susceptible to the influence of surrounding environment, in low discharge analysis, can be in detector
The temperature of sample constituents is always remained into constant, to prevent temperature from being exported to detector influence during detection；In concentrator and light
Under the mating reaction of door screen, the light that light source portion is sent carries out efficiently optically focused, reaches preferably radiation response, improves and checks essence
Degree.
Brief description of the drawings
Fig. 1 is the module frame chart of high performance liquid chromatograph.
Fig. 2 is the structural representation of the insulating box of high performance liquid chromatograph.
Fig. 3 is the structural representation of the heating rod of high performance liquid chromatograph.
Fig. 4 is the structural representation of the liquid pushing tube of high performance liquid chromatograph.
Fig. 5 is the structural representation of the detector of high performance liquid chromatograph.
Wherein：1st, aqueous solvent reservoir；2nd, organic solvent reservoir；3rd, the first degassing unit；4th, the second degassing unit；5、
Blender；6th, high-pressure pump；7th, automatic sampler；8th, chromatographic column；9th, detector；10th, recorder；11st, insulating box；12nd, the first valve
Door；13rd, the second valve；14th, circulating fan；15th, heating rod；16th, connector；17th, cylinder；18th, temperature sensor；19th, cavity；
20th, liquid pushing tube；21st, sleeve pipe；22nd, thermal insulation layer；23rd, connecting tube；24th, spongy layer；25th, air layer；26th, concentrator；27th, temperature is adjusted
Locking nub；28th, light source portion；29th, optical-electrical converter；30th, flow cell；31st, diaphragm.
Specific embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out
Clearly and completely describe, it is clear that described embodiment is only a kind of embodiment of the utility model, rather than whole realities
Apply example.Based on the embodiment in the utility model, those of ordinary skill in the art institute under the premise of creative work is not made
The every other embodiment for obtaining, belongs to protection domain of the present utility model.
To make the purpose, technical scheme and advantage of the application clearer, below in conjunction with drawings and the specific embodiments, to this
Application is described in further detail.
In the following description, the reference to " one embodiment ", " embodiment ", " example ", " example " etc. shows
So the embodiment or example of description can include special characteristic, structure, characteristic, property, element or limit, but not each reality
Applying example or example all necessarily includes special characteristic, structure, characteristic, property, element or limit.In addition, reuse phrase " according to
One embodiment of the application " is not necessarily referring to identical embodiment although it is possible to refer to identical embodiment.
According to one embodiment of the application, there is provided a kind of high performance liquid chromatograph, as shown in Fig. 1 ~ Fig. 5, the efficient liquid
Chromatography includes aqueous solvent reservoir 1, organic solvent reservoir 2 and blender 5, between aqueous solvent reservoir 1 and blender 5
The first degassing unit 3 is connected with, the second degassing unit 4 is connected between organic solvent reservoir 2 and blender 5；Blender 5 with
High-pressure pump 6 is connected, and automatic sampler 7 is provided between high-pressure pump 6 and chromatographic column 8, and chromatographic column 8 is located in insulating box 11.Chromatogram
Post 8 is connected by liquid pushing tube 20 with detector 9, and detector 9 is electrically connected with recorder 10.
In specific implementation, the first valve 12, You Jirong is connected between the degassing unit 3 of aqueous solvent reservoir 1 and first
The second valve 13 is connected between the degassing unit 4 of agent reservoir 2 and second；Water is controlled by the first valve 12 and the second valve 13
The combined amount of solvent and organic solvent, to adjust the blending ratio of aqueous solvent and organic solvent, makes its ladder for changing over time
Degree method is supplied；Meanwhile, treatment is de-gassed to aqueous solvent and organic solvent before combination, improve its precision and reliability
Property.
Insulating box 11 includes casing, the cylinder 17 in casing and is symmetrically mounted on the temperature regulation section of casing surrounding,
Temperature regulation section includes being arranged on heating rod 15 of the cabinet wall in roundabout shape by connector 16, between heating rod 15 and casing
Circulating fan 14 is provided with the cavity 19 of formation；The side of cylinder 17 is provided with temperature sensor 18, temperature sensor 18 with
Circulating fan 14 and heating rod 15 are electrically connected.
In specific implementation, preferable temperature adjustment portion is symmetrically mounted on six inner surfaces of casing, and cylinder 17 is arranged on
The center of casing, it is ensured that the ambient temperature of cylinder 17 it is uniform, meanwhile, heating rod 15 is set to roundabout shape, improves heating
Efficiency；After the temperature that temperature sensor 18 is detected is below or above preset range value, by the temperature for adjusting heating rod 15
With the air quantity of circulating fan 14, the regulation to case body temperature is realized, be easy to keep constant temperature；Its by circulating fan 14 and plus
The reasonable design of hot pin 15 and arrangement, make temperature adjustment process more uniformly with fully, improve the precision and reliability of detection.
Liquid pushing tube 20 includes sleeve pipe 21 and the connecting tube 23 in sleeve pipe 21, is set successively between connecting tube 23 and sleeve pipe 21
Air layer 25 and spongy layer 24 are equipped with, the outer wall of sleeve pipe 21 is provided with a thermal insulation layer 22；In specific implementation, the temperature of connecting tube 23
The influence of surrounding environment is not easily susceptible to, therefore, it is not required to set pipe winder unit, in low discharge analysis, can be examined in detector 9
The temperature of sample constituents is always remained constant, to prevent temperature from being exported to detector 9 influence during survey.
Detector 9 is including temperature adjustment block 27, the flow cell 30 in temperature adjustment block 27, positioned at the top of flow cell 30
Light source portion 28 and the optical-electrical converter 29 positioned at the lower section of flow cell 30, flow cell 30 connects with connecting tube 23；In specific implementation
In, the sample constituents and mobile phase eluted out from cylinder 17 are delivered to detector 9 through connecting tube 23, are then sent to flow cell 30
Inside, and irradiate flow cell 30 by power supply unit, electric signal is converted to by optical-electrical converter 29 by transmitted light, and by the electric signal
Transmit to recorder 10.
Wherein, the lower end in light source portion 28 is provided with diaphragm 31 and concentrator 26, and concentrator 26 is located at the lower end of diaphragm 31；
Under the mating reaction of concentrator 26 and diaphragm 31, the light that light source portion 28 is sent carries out efficiently optically focused, reaches and preferably irradiates
Effect, is effectively improved accuracy of detection；It is preferred that condenser is aspherical condenser, light source portion 28 is deuterium lamp.
The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or new using this practicality
Type.Various modifications to these embodiments will make it will be apparent that defined herein for those skilled in the art
General Principle can in other embodiments be realized in the case of the spirit or scope for not departing from utility model.Therefore, originally
Utility model will not be limited and the embodiments shown herein, and be to fit to and principles disclosed herein and novelty
The property consistent scope most wide of feature.
Claims (5)
1. a kind of high performance liquid chromatograph, it is characterised in that：Including aqueous solvent reservoir, organic solvent reservoir and blender,
The first degassing unit is connected between the aqueous solvent reservoir and blender, between the organic solvent reservoir and blender
It is connected with the second degassing unit；The blender is connected with high-pressure pump, is provided between the high-pressure pump and chromatographic column and entered automatically
Sample device, the chromatographic column is located in insulating box；The chromatographic column is connected by liquid pushing tube with detector, the detector with record
Instrument is electrically connected；
The insulating box includes casing, the cylinder in casing and is symmetrically mounted on the temperature regulation section of casing surrounding, described
Temperature regulation section includes being arranged on heating rod of the cabinet wall in roundabout shape, shape between the heating rod and casing by connector
Into cavity in be provided with circulating fan；The side of the cylinder is provided with temperature sensor, the temperature sensor with it is described
Circulating fan and heating rod are electrically connected；
The liquid pushing tube includes sleeve pipe and the connecting tube in sleeve pipe, and air is disposed between the connecting tube and sleeve pipe
Layer and spongy layer, described sleeve pipe outer wall are provided with a thermal insulation layer；The detector is including temperature adjustment block, positioned at temperature adjustment block
Interior flow cell, the light source portion above flow cell and the optical-electrical converter below flow cell, the flow cell and institute
State connecting tube connection.
2. high performance liquid chromatograph according to claim 1, it is characterised in that：The lower end in the light source portion is provided with diaphragm
And concentrator, the concentrator is positioned at the lower end of the diaphragm.
3. high performance liquid chromatograph according to claim 2, it is characterised in that：The condenser is aspherical condenser.
4. high performance liquid chromatograph according to claim 1, it is characterised in that：The aqueous solvent reservoir and the first degassing
The first valve is connected between unit, the second valve is connected between the organic solvent reservoir and the second degassing unit.
5. the high performance liquid chromatograph according to any one of Claims 1 to 4, it is characterised in that：The light source portion is deuterium lamp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621400957.6U CN206292212U (en) | 2016-12-20 | 2016-12-20 | High performance liquid chromatograph |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621400957.6U CN206292212U (en) | 2016-12-20 | 2016-12-20 | High performance liquid chromatograph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206292212U true CN206292212U (en) | 2017-06-30 |
Family
ID=59105269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621400957.6U Expired - Fee Related CN206292212U (en) | 2016-12-20 | 2016-12-20 | High performance liquid chromatograph |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206292212U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109001343A (en) * | 2018-10-10 | 2018-12-14 | 李素媛 | The device and method of the high performance liquid chromatography detection of protein in a kind of milk powder |
| WO2019006710A1 (en) * | 2017-07-05 | 2019-01-10 | 深圳迈瑞生物医疗电子股份有限公司 | Liquid phase analysis device, and analysis method for liquid phase analysis device |
-
2016
- 2016-12-20 CN CN201621400957.6U patent/CN206292212U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019006710A1 (en) * | 2017-07-05 | 2019-01-10 | 深圳迈瑞生物医疗电子股份有限公司 | Liquid phase analysis device, and analysis method for liquid phase analysis device |
| US11204338B2 (en) | 2017-07-05 | 2021-12-21 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Liquid phase analysis device and analysis method for liquid phase analysis device |
| CN109001343A (en) * | 2018-10-10 | 2018-12-14 | 李素媛 | The device and method of the high performance liquid chromatography detection of protein in a kind of milk powder |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170630 Termination date: 20181220 |