CN206157137U - Deaf genetic test sample box - Google Patents

Abstract

The utility model discloses a deaf genetic test sample box, including the inside inside lining that sets up of box body, lid and box body, be equipped with on the inside lining and be used for depositing the short recess of DNA collecting pipe and the long recess that is used for depositing the heparin tube, short recess all is equipped with chucking mechanism with long recess for with the body embedded Groove that deposits and spacing, but utilize the elastic deformation take -off pipe body of chucking mechanism in the recess. The sample box sample posts the bar code, leaves the space between inside lining and the lid, has placed the information management envelope in the space. The utility model discloses the sample volume that can deposit is big, and the management is orderly, and the multiple sample of a system of family generally can be deposited to a box, be convenient for transportation and storage, and avoiding clinically, extensive sampling causes the sample to obscure.

Description

A kind of deaf gene detects sampling box

Technical field

The utility model is related to medical sample container, and especially a kind of deaf gene detects sampling box.

Background technology

With the development of accurate medical science, various genetic test services are developed rapidly, used as a kind of emerging detection technique hand Section, genetic test is of great significance to the aspect tool such as clinical disease diagnosis and treatment, health control of people.Current base Because of detection technique because the requirement of the aspects such as the qualification requirement to testing agency, instrument and equipment is higher, many important detections Detection, high-flux sequence oncogene detection popularization clinically before project such as Embryonic limb bud cell needs to receive mostly than relatively low Collection sample, is addressed to qualified visiting mechanism or medical test is detected.

In recent years, have testing agency to provide the news report of false positive or Analysis of False Negative Reports frequently, to patient and family members with Come physiology and psychological injury, the prestige of testing agency is made a very bad impression, wherein a big chunk reason is due to sample What this management and misoperation was caused, such as during collection clinical sample is detected, due to Sample preservation, transport not When the situation for causing sample generation leakage, sample to obscure, it is impossible to ensure the quality of testing result, occasion a delay treatment then.

The defect of prior art specimen sample box is to cause the main cause of above consequence, such as 1) in sampling box without relatively more firm Gu and orderly sample deposit position, sample puts in a jumble.2) sampling box lacks fixed shockproof cushioning measure, usual during transport Using some simple padded coamings are added in box, such as newspaper, foam are easily contacted with sampling pipe, cause label thereon Come off or be stained, cause sample to be obscured.3) due to jolting during transport, probably due to collision, causes sample between sample and sample Damage so as to cause the cross pollution between sample, make testing result inaccurate.4) reliable sample identification tracking system is lacked, It is unfavorable for that patient understands the effective management of detection progress and reviewer to sample information, causes sample to be obscured, error report is prolonged Mistaken diagnosis is controlled.

Also, existing clinical sample sampling box is usually metallic article or bubble chamber, great amount of samples can be deposited, it is relatively more suitable Close Clinical Institutions collection great amount of samples and hospital internal short distance transport is used, but it has the disadvantage that internal specimen is mixed and puts, and lacks solid Fixed shockproof cushioning measure, is easily damaged sample, so as to cause and the cross pollution between other samples, is not suitable for patient or trouble Person's family sample collection is sent to inspection body, carries out the detection projects such as genetic test.Some mechanisms can use papery sampling box, It is cheap, have the disadvantage that the sample size that can be deposited is few, type is single, is easily damaged deformation, is not suitable for long distance transportation.

Utility model content

Utility model purpose：For the defect that above-mentioned prior art is present, the utility model aims to provide a kind of deaf base Because detecting specimen sample box.

Technical scheme：A kind of deaf gene detects sampling box, including the liner that box body, lid and tray interior are arranged, The interior lining is provided with the short groove for depositing DNA collecting pipes and the long recess for depositing heparin tube, the short groove and Long recess is equipped with clamping body, and the embedded groove of the body for will deposit in groove is simultaneously spacing, using the elasticity of clamping body Deformation can be taken off body.

Further, the short groove is 2, and long recess is 6.

Further, short groove and long recess are extended with and are available for finger to stretch into the extension slot for taking body.

Further, the clamping body includes being located at two position-limited edges that the lateral inside grooves of body two extend.

Further, the liner is made using plastic uptake material.

Further, the lid includes upper lid and by the upper front side cap for covering and extending, before the front side cap and box body Side is equipped with magnet, and when covering lid, the leading flank of front side cap and box body is by together with magnet adsorption.

Further, the blood sampling pipe outer wall and DNA collect pipe outer wall and post bar code, for information inquiry and management, Space is left between the liner and lid, information management envelope is placed with space.

Further, blood sampling bag clamping is placed with described information management envelope, blood sampling bag clamping internal memory is placed with blood taking needle and adopts Blood filter paper, posts bar code, for information inquiry and management in blood sampling bag clamping.

Further, personal inquirying card is placed with described information management envelope, bar code and inspection is printed on personal inquirying card Announcement querying method is observed and predicted, for information inquiry.

Further, case information registration form is placed with described information management envelope, for managing patient case information, The case information registration form is provided with the stickup area for pasting heparin tube bar code or DNA bar codes.

Beneficial effect：

(1) clamping body that the utility model is arranged can firmly clamping heparin tube and DNA collecting pipes, storage blood sampling in box The liner of pipe and DNA collecting pipes is formed and unconventional sponge material using the compacting of plastic uptake material, more firmly, even if box falls It is not easy to make the heparin tube and centrifuge tube of the inside knocking-on to ground, so as to protecting sample well and preventing sample contamination；

(2) be provided with the utility model box body multiple short grooves for depositing DNA collecting pipes and it is multiple for storage adopt The long recess of blood vessel, the sample size that can be deposited is big, and management is orderly.One box can typically deposit a family at least 3 people The sample of (father, mother, children etc.), it is to avoid clinically extensive sampling causes sample to obscure；

(3) sampling box is used cooperatively with bar code, conveniently carries out sample verification and management；Heparin tube, DNA in box is collected Pipe, blood sampling bag clamping all post bar code, and typing sample information is quick and precisely；There is personal inquirying card in box, patient voluntarily retains, and Quick Response Code input barcode number can be scanned and obtain the information such as detection progress and examining report in real time；

(4) the utility model can flexibly select sample mode, doctor to be selected not according to patient class and family situation Same sample mode, gathers polytype multiple clinical samples.Typically use heparin tube collecting sample, it is also possible to which hospital is existing The family DNA sample for having extracted, infant can be with blood sampling bag clamping.

Description of the drawings

Fig. 1 is sampling box structural representation；

Fig. 2 (a), Fig. 2 (b) are inner lining structure schematic diagrams.

Specific embodiment

Below by a most preferred embodiment and combine accompanying drawing the technical program is described in detail.

As shown in figure 1, a kind of deaf gene detects sampling box, (such as blood, amniotic fluid, wipe for depositing transport clinical sample Son etc.), it is particularly suited for the collection of genetic test family sample, each sampling box can deposit a family at least 3 types Sample.Including the liner 3 that box body 1, lid 2 and the inside of box body 1 are arranged, liner 3 is made using plastic uptake material.

Liner 3 is provided with 2 short grooves 31 and 6 long recess for being used to deposit heparin tube for depositing DNA collecting pipes 32；DNA collecting pipes (1.5 or 2ml) are used for collecting trace sample (such as buccal swab, the DNA that extracted), and heparin tube is for receiving Sample (such as blood, amniotic fluid, tissue) within collection 10ml, short groove 31 and the concrete size of long recess 32 and the pipe of storage in groove Body size matches, and can accommodate body and slightly stay redundancy to be defined, redundancy is about 1-2mm, the short groove 31 and long recess 32 are equipped with clamping body, and the embedded groove of the body for will deposit in groove is simultaneously spacing, using the elastic deformation of clamping body Can be taken off body.Clamping body in the present embodiment includes being located at two position-limited edges that the lateral inside grooves of body two extend, and puts Gently firmly sample tube can be firmly pressed in the groove of liner 3 when entering body, play and protect sample to prevent it from groove The effect for coming off or shifting.Those skilled in the art can select other clamping bodies according to general knowledge, and for example, clamping body includes one Bar is across from left to right the position-limited edge above body, and body is put between position-limited edge and groove during storage body；Can also Clamping body is set to into two fixing bands or the static line that groove both sides are stretched out, is put into after body and fixing band or static line is existed Body top knotting setting fastening.

The short groove 31 and long recess 32 are extended with and are available for finger to stretch into the extension slot 33 for taking body, the present embodiment The middle mode for adopting for：As shown in Fig. 2 (a), leave in the front end of short groove 31 and long recess 32 and be available for finger to stretch into taking The space of body, the length 0.5-1.5cm longer than the length of DNA collecting pipe of short groove 31, the length of long recess 32 compares heparin tube The long 0.5-2cm of length；Can also adopt and circular arc extension slot 33, the size of extension slot 33, shape are set in the both sides of body Can sets itself as needed, using the semi-circular recesses of diameter 1-2cm in the present embodiment, shown in such as Fig. 2 (b).

Blood sampling bag clamping is placed with box body 1, the blood sampling bag clamping internal memory is placed with blood sampling filter paper, blood collecting card in the present embodiment Bag internal memory is placed with 4 blood sampling filter papers for collecting infant foot bottom blood equal samples.

Front side cap 22 this two parts that lid 2 includes upper lid 21 and extended by upper lid 21, when lid 2 is covered, front side cap 22 contact with the leading flank of box body 1, and lid 2 is inlaid with magnet 4 with box body 1 at the position for contacting, when covering lid 2, Both are attached together by the attraction between inner magnet 4, facilitate box opening and closing, those skilled in the art also dependent on General knowledge selects other modes to buckle lid 2 and box body 1.The utility model box body 1 adopt portable sampling box, compact practicality, With a book almost, sampling box good looking appearance can be made size using multiple material, convenient to produce and sell and accumulating, and be fitted Mechanization, automatic packaging are closed, is easy to modern management, is saved manpower, improves efficiency.Box body 1 adopts papery in the present embodiment Packaging material make, lightweight, low cost, convenient transport, environmental protection, while the wasting of resources can be reduced with Reusability.

Deaf gene detection sampling box is used cooperatively with bar code mark, can easily carry out sample tracing management and detection report Accuse inquiry.

The space of high 0.5-2cm is left between liner 3 and lid 2 inside box body 1, information management letter is placed with space Storage case information registration form, blood sampling bag clamping (can not put), personal inquirying card and sampling box explanation in envelope, information management envelope Book.

Case information registration form is used to register patient cases' information, including person under inspection and family members' essential information, person under inspection's disease History and past medical history, family's medical history, iconography detection, sample collection information, the feelings letter of consent of deaf gene detection and coherent detection Report.The stickup for pasting heparin tube bar code, DNA bar codes or filter paper Blood piece sample bar code is provided with sample collection information Area.

Sampling box specification, for the sampling box operating instruction that hospital and testing agency use；Specification is furnished with very shape The flow chart of elephant, facilitates patient and family members, medical institutions and testing agency to fill in relevant information according to specification, specification sampling and Receive, manage sample, even from far-off regions, the medical institutions of reduced levels can also complete sampling work.

Blood sampling bag clamping internal memory is placed with blood collecting card, 2 blood taking needles, 4 blood sampling filter papers and is available for being pasted onto medical record information and steps on Bar code on note table, for gathering neonate vola blood sample, is printed on acquisition technique specification on blood collecting card, advise according to acquisition technique Model collection drop has the filter paper Blood piece of vola blood；

Bar code and examining report querying method are printed on personal inquirying card, for information inquiry, bar code include Quick Response Code and Bar code, by scanning Quick Response Code, input barcode number can inquire about detection progress and examining report content.

Blood sampling pipe outer wall, DNA to be collected and post bar code in pipe outer wall and blood sampling bag clamping, for information inquiry and management, is led to The Quick Response Code of overscanning sample bar code and sampling box, can easily carry out sample reception and process, manage tracking and report queries. The present embodiment is pasted with a fixed bar code and two bar codes with not viscous side in blood sampling pipe outer wall, and user never glues side can Bar code is taken easily to tear, and is pasted onto the correspondence of case information registration form and paste area, sample is corresponded with information, prevented Mix up sample, the usually medical institutions of collecting sample facilitate follow-up patient's scanning and query-related information pasting；The fixation Bar code is not torn, and fixation is pasted onto blood sampling pipe outer wall, for cross-check information.Also it is placed with and bar code one on blood collecting card in blood sampling bag clamping The bar-code label paper of cause.Take bar code off from label paper to be pasted onto《Case information registration form》Sample collection information at, make sample This is corresponded with information, prevents sample from obscuring.

Specifically used method is as follows：

Medical institutions are sampled to specifications after sampling box is received, and sealing after the completion of sampling is placed on equipped with ice bag In transport case, transport to specified testing agency.This sampling box is designed and developed mainly for the family for having 3 members, each family In each individuality at least gather a type of sample.

First, hospital's sampling flow process：

1. hospital is received after sampling box, log-on message management system, is clicked on and is received button, is checked in box according to table 1 List of articles.

List of articles in the sampling box of table 1

Title	Quantity
		Sampling box specification	1 part
Case information registration form	1 part
		Personal inquirying card	1 part
EDTA anticoagulant blood-collecting pipe *	6
		Bar code	1 part
DNA collecting pipe *	2
		Blood sampling bag clamping *	1 part

Wherein, mark * to select sample mode, doctor to select different sample modes according to patient class, typically push away Recommend and use heparin tube collecting sample, if infant can be with blood sampling bag clamping, if there is extracted good family DNA sample in hospital This, can use DNA collecting pipes (1.5 or 2ml).

2. hospital will one by one tell about Informed Consent Form content before sample is collected with person under inspection, and ask person under inspection knowing the inside story Sign on letter of consent.Person under inspection is transferred to preserve the personal inquirying card containing Quick Response Code in addition.

3. different types of sample collection requires as follows：

(1) blood collection

Before blood collection or after having gathered, the bar code as the serial number on the heparin tube used is labelled to into case letter The correspondence position of breath registration form, and choose sample type.

Sampling request：Adult is not less than 5ml；Infant or children are not less than 2ml blood sampling volumes, and the sample after collection is in -20 Degree Celsius preserve.

(2) DNA sample collection

Before DNA sample collection or after having gathered, by the bar code of serial number is labelled to disease as on collecting pipe in sampling box The correspondence position of example information registration form, and choose sample type.

Sampling request：DNA concentration is no less than 30ng/ul, and DNA total amounts are no less than 3 μ g (needing backup).Short time can keep in In 4 DEG C of refrigerators, -20 DEG C should be stored in for a long time.

(3) filter paper of taking a blood sample is gathered

Before blood sampling filter paper collection or after gather, by sampling box as on filter paper of taking a blood sample serial number bar code The correspondence position of case information registration form is labelled to, and chooses sample type.

Sampling request：More than 3 spots of taking a blood sample of collection, and the diameter of each blood cake cannot be less than 8mm.Normal temperature lucifuge is dried More than 4 hours and it is put into blood sampling bag clamping.

4. fill in by information such as inspection people's information, familial inheritance medical history, sample collections.By other inspections related to detection project Survey the relevant position of the stickup of report copy and case information registration form.Doctor audits one by one the sound in case information registration form It is bright and sign.

5. information verification, conscientiously more than verification whether operation is fully completed, and case information registration form is loaded into sampling box letter Breath management envelope, confirmation form 2 returns article in inventory whether in sampling box.

Table 2 returns inventory

Title	Quantity	Verification
			Case information registration form	1 part
EDTA anticoagulant blood-collecting pipes (selection)	6
			DNA collecting pipes (selection)	2
Sampling box specification	1 part
			Blood sampling bag clamping (selection)	1 part
Sampling box	1

Note：Beat " √ " on verification hurdle after verification is correct.

6. sample is returned and posted, and arranges ice bag or dry ice to transport censorship to specified testing agency in sample.

2nd, testing agency's testing process

1. testing agency is received after sampling box, log-on message management system, is clicked on and is received button, and the scanning sample box back side Bar code carry out sample reception, and check the article in box, such as following table.

Title	Quantity
		Case information registration form	1 part
EDTA anticoagulant blood-collecting pipes	6
		DNA collecting pipes	2
Sampling box specification	1 part
		Blood sampling bag clamping	1

2. in scanning sample box equipped with sample heparin tube either DNA collecting pipes or blood sampling filter paper on bar code, will Sample message typing information management system in case information registration form, and whether confirmatory sample is qualified.Case information is registered All Data Enter information management systems in table.

3. signed case information registration form is achieved.

4. the operation such as dispensed, checked, being stored in strict accordance with code.And state is carried out in information management system more Newly.

5. testing result, sequencing master data are uploaded to information management system by testing agency after the completion of detecting.

3rd, progress and report queries are detected

Patient or relatives carry out the inquiry of detection progress and result report by the personal inquirying card retained.

Mode 1. scans the Quick Response Code on card with mobile phone, after page open, the numeral being input under the bar code of Quick Response Code lower section, Click on " inquiry " button, you can check progress and examining report.

Mode 2. opens computer browser input information management system referral web site, after page open, under input Quick Response Code Numeral under square bar code, clicks on " inquiry " button, you can check progress and examining report.

Additionally, this sampling box can facilitate family or the trouble regional or that hospital's sampling is gone without the time that medical condition falls behind Person voluntarily samples.Method is：After receiving sampling box, case information registration form is filled in, voluntarily according to the blood sampling rule in blood sampling bag clamping Model collection infant foot bottom blood sample, or the sample of the convenient collection such as Stomatocyte or finger tip blood of collection adult is put into DNA receipts Collector.After sample collection is finished, sampling box is addressed to into testing agency and is detected.

Also, this kit is applicable to focus on the family of individual privacy or the genetic test demand of patient.Method is：Receive To after sampling box, case information registration form is filled in, be directed to the content of the information such as personal name and can omit do not fill out.Voluntarily according to Blood sampling specification in blood sampling bag clamping gathers infant foot bottom blood sample, or the Stomatocyte or finger tip blood equal samples of collection adult are put Enter DNA collecting pipes；Also can be to medical institutions' commission collection blood equal samples, certainly be about to sampling box is addressed to testing agency to patient Detected.Detection and patient query's report only by the Quick Response Code and bar code in sampling box, are not related in testing staff and report And patient is reluctant the content revealed.The embodiment respects fully patients' privacy.

The above is only preferred embodiment of the present utility model, it should be pointed out that：For the ordinary skill people of the art For member, on the premise of without departing from the utility model principle, some improvements and modifications can also be made, these improvements and modifications Also should be regarded as protection domain of the present utility model.

Claims (8)

1. a kind of deaf gene detects the liner arranged inside sample sampling box, including box body (1), lid (2) and box body (1) (3), it is characterised in that the liner (3) is provided with the short groove (31) for depositing DNA collecting pipes and for depositing heparin tube Long recess (32), the short groove (31) and long recess (32) are equipped with clamping body, for the body that will be deposited in groove Embedded groove is simultaneously spacing, and using the elastic deformation of clamping body body is can be taken off.

2. deaf gene according to claim 1 detects sampling box, it is characterised in that the short groove (31) is 2, long Groove (32) is 6.

3. deaf gene according to claim 1 detects sampling box, it is characterised in that the short groove (31) and long recess (32) it is extended with and is available for finger to stretch into the extension slot (33) for taking body.

4. deaf gene according to claim 1 detects sampling box, it is characterised in that the clamping body includes being located at pipe Two position-limited edges that the lateral inside grooves of body two extend.

5. deaf gene according to claim 1 detects sampling box, it is characterised in that the liner (3) is using plastic uptake material Material is made.

6. deaf gene according to claim 1 detects sampling box, it is characterised in that the lid (2) is including upper lid (21) front side cap (22) for and by upper lid (21) extending, the front side cap (22) is equipped with magnet with the leading flank of box body (1) (4) when, covering lid (2), front side cap (22) is attached together with the leading flank of box body (1) by magnet (4).

7. deaf gene according to claim 1 detects sampling box, it is characterised in that the blood sampling pipe outer wall and DNA are received Collection pipe outer wall posts bar code, for information inquiry and management, space is left between the liner (3) and lid (2), in space It is placed with information management envelope.

8. deaf gene according to claim 7 detects sampling box, it is characterised in that place in described information management envelope There is blood sampling bag clamping, blood sampling bag clamping internal memory is placed with blood taking needle and blood sampling filter paper, bar code is posted in blood sampling bag clamping, for information inquiry And management.