CN205826515U - Acoustical signal detector based on surface wave and reflecting light sonomicroscope - Google Patents
Acoustical signal detector based on surface wave and reflecting light sonomicroscope Download PDFInfo
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- CN205826515U CN205826515U CN201620547452.6U CN201620547452U CN205826515U CN 205826515 U CN205826515 U CN 205826515U CN 201620547452 U CN201620547452 U CN 201620547452U CN 205826515 U CN205826515 U CN 205826515U
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Abstract
This utility model is applicable to photoacoustic imaging acoustic pressure detection technique field, provide a kind of acoustical signal detector based on surface wave and reflecting light sonomicroscope, this acoustical signal detector includes the prism with two planes being parallel to each other, a plane in described two planes being parallel to each other is coated with thin film, and described thin film is for detecting the photoacoustic signal through medium transmission.This acoustical signal detector is due to the method that have employed optical sensing refractive index so that object under test has label-free, contactless sensing detection feature, and is capable of detective bandwidth, detects sensitive advantage.This acoustical signal detector based on surface wave is applied in reflecting light sonomicroscope, it is possible to achieve the image checking of biological living.
Description
Technical field
This utility model belongs to photoacoustic imaging acoustic pressure detection technique field, particularly relates to a kind of acoustical signal based on surface wave
Detector and reflecting light sonomicroscope.
Background technology
The extraction using piezoelectric method (instrument is referred to as ultrasonic transducer) to carry out sound pressure signal is current main flow, many classes
Topic group utilizes Piezoelectric detector to carry out the research of photoacoustic imaging, achieves plentiful and substantial achievement in research.Although the development of this technology is relatively
Maturation, application surface are the most extensive, but it there is also some shortcomings being difficult to overcome.Such as, this technology cannot realize Gao Ling simultaneously
Sensitivity, high-frequency detection.Using piezoquartz to receive ultrasonic signal, sensitivity is conflicting with reception frequency, piezoelectricity
The area the least reception frequency of crystal is the highest, and correspondence is that sensitivity is the lowest.Piezoelectric detector cannot realize a detection,
The signal that it is detected is the average effect of piezoquartz area.Piezoquartz is used to carry out the pickup of photoacoustic signal, it is necessary to
Sample and probe between, restricted by the attribute of piezoelectric own, ultrasonic transducer generally exist surveying tape width (about 40～
60MHz) and the shortcoming of sensitivity low (noise equivalent sound pressure: hundreds of～upper kPa).
Utility model content
Technical problem to be solved in the utility model is to provide a kind of acoustical signal detector based on surface wave with anti-
Penetrate formula photoacoustic microscope, it is intended to the problem solving existing detector surveying tape width.
This utility model is achieved in that a kind of acoustical signal detector based on surface wave, is parallel to each other including having
The prism of two planes, described in a plane in two planes being parallel to each other be coated with thin film, described thin film is used for detecting
Photoacoustic signal through medium transmission.
Further, described thin film is metallic film or graphene film.
This utility model also provides for a kind of acoustical signal detector based on surface wave, including multimode fibre, described multimode light
Fibre include covering and the fibre core being placed in covering, the fibre core of described multimode fibre have one with described multimode fibre length extension side
To parallel cross section, described covering has a breach making described cross section be exposed to outside described covering, and described cross section is positioned at described
Indentation, there, described cross section is coated with thin film, and described thin film is for detecting the photoacoustic signal through medium transmission.
Further, described thin film is metallic film or graphene film.
This utility model also provides for the reflecting light sonomicroscope of a kind of acoustic pressure detector based on surface wave, including reflection
Formula microcobjective harmony signal sensor；
Described catoptric micro objective is placed in the top of described acoustical signal detector, for being gathered by the laser that lasing light emitter is launched
Jiao is irradiated on object under test so that described object under test absorbs described laser and produces photoacoustic signal, and described photoacoustic signal is anti-
Described acoustical signal detector is entered after the medium being transferred through above object under test reflects；
Described acoustical signal detector is placed in the top of described object under test and is positioned at the lower section of described catoptric micro objective,
For detection through the photoacoustic signal of medium transmission, and according to described photoacoustic signal generate object under test be used for make object under test become
The detection spectrum of picture.
Further, described acoustical signal detector is that lower planes is parallel and lower plane is coated with the prism of thin film or is coated with
The multimode fibre of thin film, described thin film is for detecting the photoacoustic signal through medium transmission；
Described multimode fibre includes covering and the fibre core being placed in covering, and the fibre core of described multimode fibre has one with described
The cross section that multimode fibre length bearing of trend is parallel, described covering has one makes what described cross section was exposed to outside described covering to lack
Mouthful, described cross section is positioned at described indentation, there, and described thin film is plated on described cross section.
Further, described reflecting light sonomicroscope also includes excitation light path assembly and detection optical path component；
Described excitation light path assembly focuses on described object under test, to excite object under test to produce for emission pulse laser
Third contact of a total solar or lunar eclipse acoustical signal；
Described detection optical path component is used for sending continuous laser and incides on described acoustical signal detector complete interior anti-to carry out
Penetrate, and detect the variations in refractive index of the reflected light signal after total internal reflection.
Further, described excitation light path assembly includes tunable laser, diaphragm, expands device, focusing coupled lens
With the first single-mode fiber；
Described tunable laser is used for producing pulse laser；
Described diaphragm is placed in the front of described tunable laser, for adjusting the beam size of pulse laser；
The described device that expands is for being enlarged from the light beam of described diaphragm pulse laser out；
Described focusing coupled lens expands the front of device described in being placed in, for being entered by the pulse laser expanded through light beam
Line focusing couples；
Described first single-mode fiber is placed in the front of described focusing coupled lens, for focusing on the pulse laser after coupling
It is transferred on described catoptric micro objective.
Further, described excitation light path assembly also includes planar light device and plane mirror；
Described planar light device is placed in the front of described single-mode fiber, for the laser by described first single-mode fiber output
Source expands into directrix plane light；
Described plane mirror is placed in the front of described planar light device, makes pulse laser energy for changing the direction of pulse laser
Enter on described catoptric micro objective.
Further, described detection optical path component includes laser instrument, wave plate, the first focusing coupled lens, the second single-mode optics
Fine, the first collimation bonder, the second collimation bonder, the 3rd single-mode fiber, the second focusing coupled lens, polarization beam apparatus peace
Weighing apparatus detector；A tank is placed in the lower section of described acoustical signal detector, and described object under test is placed in the lower section of described tank；
Described laser instrument is used for producing continuous laser；
Described wave plate is placed in the front of described laser instrument, for by described continuous laser furnishing rotatory polarization；
Described first focuses on coupled lens is placed in the front of described wave plate, for rotatory polarization is focused coupling；
Described second single-mode fiber be placed in described first focus on coupled lens front, for by focus on coupling after continuous
Laser is transmitted；
Described first, second collimation bonder is placed in the both sides of described acoustical signal detector, described first collimation bonder
For carrying out collimation coupling from described second single-mode fiber light out, described second collimation bonder is for will be from described sound
After in signal sensor, light out carries out collimation coupling, output is to described 3rd single-mode fiber；
Described 3rd single-mode fiber collimates bonder reflection light out for transmission from described second；
Described second focuses on coupled lens for described reflection light is focused coupling；
Described polarization beam apparatus reflection light after being focused coupling is split, and is divided into P polarization light and S-polarization
Light；
After described balanced detector is placed in described polarization beam apparatus, for detecting described P polarization light and described S-polarization light
Refractive index variable quantity.
Further, described detection optical path component includes that plane mirror, described plane mirror are placed in the side of polarization beam apparatus, uses
In adjusting the direction from described polarization beam apparatus S-polarization light out.
Further, described acoustic pressure detector also includes imaging device, and described imaging device is according to described balanced detector
The refractive index variable quantity detected generates the photoacoustic imaging axonometric chart of object under test.
Further, described reflecting light sonomicroscope also includes three-D electric platform, described catoptric micro objective and
Described acoustical signal detector is fixedly arranged on three-D electric platform.
This utility model compared with prior art, has the beneficial effects that: described acoustical signal detector based on surface wave
Thin film is plated on a face in two planes being parallel to each other on prism so that thin film can detect the light through medium transmission
Acoustical signal, the change of this photoacoustic signal reflects the change of refractive index, such that it is able to realize some detection.This acoustical signal detector by
In the method that have employed optical sensing refractive index so that object under test has label-free, contactless sensing detection feature, and
And be capable of detective bandwidth, detect sensitive advantage.This acoustical signal detector based on surface wave is applied to reflecting light
In sonomicroscope, it is possible to achieve the image checking of biological living.
Accompanying drawing explanation
Fig. 1 is a kind of structural representation of the acoustical signal detector based on surface wave that this utility model embodiment provides；
Fig. 2 is the reflecting light sonomicroscope of the acoustical signal detector based on surface wave that this utility model embodiment provides
Structural representation；
Fig. 3 is the another kind of structural representation of acoustical signal detector based on surface wave；
Fig. 4 is the photoacoustic signal schematic diagram using acoustical signal detector based on surface wave of the present utility model to record；
Fig. 5 is the frequency spectrum of laser acoustics scope using acoustical signal detector based on surface wave of the present utility model to detect
Schematic diagram；
Fig. 6 is that the reflecting light sonomicroscope using acoustical signal detector based on surface wave of the present utility model detects
The photoacoustic imaging schematic diagram of human hair sample.
Detailed description of the invention
In order to make the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with accompanying drawing and enforcement
Example, is further elaborated to this utility model.Should be appreciated that specific embodiment described herein is only in order to explain
This utility model, is not used to limit this utility model.
A kind of acoustical signal detector based on surface wave is including having the prism of two planes being parallel to each other, the most flat
A plane in two planes of row is coated with thin film, and thin film is for detecting the photoacoustic signal through medium transmission.
Should acoustical signal detector based on surface wave based on total internal reflection principle, utilize surface wave high sensitivity sensing former
Reason, uses the thin film being plated on one of them plane in two planes being parallel to each other just can detect the light through medium transmission
Acoustical signal.
In the present embodiment, thin film is metallic film or graphene film.Prism is bench-type prism, this bench-type prism transversal
Face is circular or rectangle, and longitudinal section is trapezoidal.The base material that metallic film or graphene film produce as surface wave, surface
The thickness of metallic film and the thickness of graphene film can be replaced, and different thin film layer thickness can have shadow to highest detection sensitivity
Ring.Metallic film can be gold film, silverskin etc., it is preferred that the thickness of the metal film plated about 45nm.Graphene film can divide
Being deposited with for multilamellar, it is preferred that graphene film has 5 layer graphenes, thickness is 1.7nm.
As it is shown on figure 3, a kind of acoustical signal detector based on surface wave, including multimode fibre 301, multimode fibre 301 wraps
Include covering 302 and the fibre core 303 being placed in covering 302, the fibre core 303 of multimode fibre 301 have one with multimode fibre 301 length
The cross section 304 that bearing of trend is parallel, covering 302 has a breach 305, and cross section 304 is positioned at breach 305, and breach 305 makes cross section
304 are exposed to outside, and cross section 304 is coated with thin film, and thin film is for detecting the photoacoustic signal through medium transmission.
In the present embodiment, thin film is metallic film or graphene film.Metallic film or graphene film are as surface wave
The base material produced, the thickness of surface metal thin film and the thickness of graphene film can be set to difference according to reality application
Value, highest detection sensitivity can be had an impact by different thin film layer thickness.Metallic film can be gold film, silverskin etc., it is preferred that
The thickness of the metal film plated about 45nm.Graphene film can be divided into multilamellar to be deposited with, it is preferred that graphene film has
5 layer graphenes, thickness is 1.7nm.
Refer to the acoustic pressure detector based on surface wave that Fig. 1, Fig. 1 provide for this utility model one of which embodiment
The structural representation of reflecting light sonomicroscope, is somebody's turn to do acoustic pressure detector based on surface wave, including catoptric micro objective 101 He
Acoustical signal detector 102.Catoptric micro objective 101 is placed in the top of acoustical signal detector 102, for launched by lasing light emitter
Laser focusing is irradiated on object under test 103.Object under test 103 absorbs laser and produces photoacoustic signal, and photoacoustic signal reversely passes
Defeated medium above object under test occurs to reflect laggard entering tone signal sensor 102.Object under test 103 in Fig. 1 is with little
Mouse is as a signal, but is not limited to mouselet, and this object under test can be biological thick sample, biopsy samples, such as: each
Plant cell, various animals etc..Acoustical signal detector 102 is placed in the top of object under test 103, for detecting the light through medium transmission
Acoustical signal, and the detection spectrum of object under test 103 is generated according to photoacoustic signal, this detection spectrum may be used to object under test imaging.
Should the reflecting light sonomicroscope of acoustic pressure detector based on surface wave be integrally-built excites and receive photoacoustic signal and do not do
Disturb.
Acoustical signal detector 102 can be that lower planes is parallel and one of them plane is coated with the prism of thin film, or, can
To be the multimode fibre being coated with thin film.This prism can be bench-type prism, and thin film can be plated on the lower plane of bench-type prism, or
Person, thin film is plated in the core cross sections of multimode fibre.Thin film is metallic film or graphene film.
The base material that metallic film or graphene film produce as surface wave, the thickness of surface metal thin film and graphite
The thickness of alkene thin film can be replaced, and highest detection sensitivity can be had an impact by different thin film layer thickness.Metallic film can be gold
Film, silverskin etc., it is preferred that the thickness of the metal film plated about 45nm.Graphene film can be divided into multilamellar to be deposited with, preferably
, graphene film has 5 layer graphenes, and thickness is 1.7nm.
Use metallic film as the base material of generation surface wave, bench-type prism or single-mode optics will be plated on by metallic film
On fine surface, so that SPR difference photo-acoustic detection theory detection sensitivity can reach 10-8RIU, corresponds in water
The sound pressure variations of 0.07Pa, far above the detection sensitivity of existing ultrasonic transducer.Meanwhile, the response time exciting SPR is to receive
Second-time, corresponding ideal bandwidth can reach 1000MHz, also far above the frequency response width of existing ultrasonic transducer.
Graphene film is compared metallic film and is had more preferable pyroconductivity, bigger hot injury's threshold value, is more suitable for Gao Gong
Rate pulse laser is as the excitaton source of photoacoustic signal.Further, graphene film is compared metallic film and is had higher free electron
Density, therefore Graphene responds faster for the soak time of light, can reach psec, even femtosecond magnitude, the ideal of its correspondence
Bandwidth is wider.
As it is shown on figure 3, multimode fibre 301 includes covering 302 and the fibre core 303 being placed in covering, the fibre of multimode fibre 301
Core 303 has a cross section 304 parallel with multimode fibre 301 length bearing of trend, and covering 302 has a breach 305, cross section
304 are positioned at breach 305, and breach 305 makes cross section 304 be exposed to outside covering 302, and thin film is plated on cross section 304.Specifically
, the covering 302 of multimode fibre 301 is sectioned one section along the direction vertical with length, makes the outer surface of fibre core 302 expose
Coming, the outer surface of exposed fibre core 302 out can be outside 1/2nd of the fibre core 303 of one section of covering 302 correspondence sectioned
Surface, 1/3rd outer surfaces etc..The most exposed fibre core 302 out is sectioned along the length direction of multimode fibre 301,
Paralleling with the length bearing of trend of multimode fibre 301 in the cross section 304 obtained, then plates metallic film or stone on cross section 304
Ink alkene thin film.
Should use catoptric micro objective that laser gathering is irradiated to object under test by acoustical signal detector based on surface wave
On 103 so that object under test 103 absorbs laser and produces photoacoustic signal, acoustical signal detector is used to detect through medium the most again
There is the photoacoustic signal of refraction in transmission, and generate the detection spectrum of object under test according to the photoacoustic signal after described refraction.This sound is believed
Number detector is due to the method that have employed optical sensing refractive index so that object under test has label-free, contactless sensing
Detection feature, and be capable of detective bandwidth, detect sensitive advantage.
Refer to the reflecting light sonomicroscope structure that Fig. 2, Fig. 2 are this utility model acoustic pressure based on surface wave detector
Schematic diagram, this reflecting light sonomicroscope include catoptric micro objective 101, acoustical signal detector 102, excitation light path assembly and
Detection optical path component.
Catoptric micro objective 101 is placed in the top of acoustical signal detector 102, for laser focusing is irradiated to determinand
On body 103.Object under test 103 absorbs laser and produces photoacoustic signal, and photoacoustic signal reverse transfer is after medium reflects
Enter acoustical signal detector 102.
Acoustical signal detector 102 is placed in the top of object under test 103, for detecting the photoacoustic signal through medium transmission, and
The detection spectrum of object under test 103 is generated according to photoacoustic signal.Detection light path devices 102 is to be coated with bench-type prism or the plating of thin film
Having the single-mode fiber 301 of thin film, thin film is plated on the lower surface of bench-type prism, or thin film is plated on the fibre core 303 of single-mode fiber 301
On cross section.Thin film is metallic film or graphene film.Point about metallic film or graphene film refer to upper one in fact
Execute example, do not repeat them here.
Excitation light path assembly focuses on object under test 103, to excite object under test 103 to produce for emission pulse laser
Photoacoustic signal.
Excitation light path assembly includes tunable laser 104, diaphragm 105, expands device 106, focusing coupled lens 107 and
First single-mode fiber 108.
Tunable laser 104 is used for producing pulse laser, and pulse laser is used for photoacoustic imaging.As one of them example
Son, the wavelength of this pulse laser is 532nm, pulse width is 1.8ns, and the pulse laser of other wavelength and pulse width can also
Realize photoacoustic imaging, during photoacoustic imaging, need to be adjusted other according to wavelength and the pulse width of pulse laser
The parameter of optics.
Diaphragm 105 is placed in the front of tunable laser 104, for adjusting the beam size of pulse laser.
Expand device 106 for being enlarged from the light beam of diaphragm 105 pulse laser out.Expand device 106 to wrap
Include lens 1061, pinhole lens 1062 and lens 1063.
Focus on coupled lens 107 and be placed in the front expanding device 106, for the pulse laser expanded through light beam is carried out
Focus on coupling.
First single-mode fiber 108 is placed in the front focusing on coupled lens 107, and the pulse laser after focusing on coupling passes
It is passed on catoptric micro objective 101.The laser of the first single-mode fiber 108 exports from fiber port 111.Utilize optical fiber
Pulse laser is carried out coupled transfer, it is simply that utilize the stability of fiber-optic transfer, it is ensured that during platform scanner imaging, light
Signal includes catoptric micro objective 101 in the core of system, is not changed in bench-type prism such that it is able to ensure all
Photoacoustic imaging is realized under the conditions of one.
Excitation light path assembly also includes planar light device 109 and plane mirror 110.Planar light device 109 is placed in single-mode fiber
The front of 108, for expanding into directrix plane light by the lasing light emitter that the first single-mode fiber 108 exports.Plane mirror 110 is placed in planar light
The front of device 109, can enter into catoptric micro objective 101 for changing the direction of pulse laser.
Pulse laser through diaphragm 105, expand device 106 and focus on after coupled lens 107, enter the anti-of high-NA
Catoptric micro objective 101, as excitaton source, produces sound pressure signal.The generation of sound pressure signal is owing to pulse laser is through high numerical aperture
The catoptric micro objective 101 in footpath focuses on object under test 103, and sample is by absorbing, because of the generation of transient heat buoyancy effect
Broadband setting-up ripple (i.e. photoacoustic signal).The photoacoustic signal produced is delivered to the surface of acoustical signal detector 102 by medium, causes
The change of refractive index.This medium can be air, liquid, such as, water, oil, solution etc..Variations in refractive index is owing to acoustical signal is drawn
Playing the minor variations of Media density, such as, water or air, the change of material density, one of performance is exactly the change of refractive index.
Detection optical path component is used for sending continuous laser and incides to carry out total internal reflection on acoustical signal detector 102, and
The variations in refractive index of detection reflected light signal after total internal reflection.
Detection optical path component includes that laser instrument 201, wave plate 202, first focus on coupled lens the 203, second single-mode fiber
204, the first collimation bonder 205, second collimate bonder the 206, the 3rd single-mode fiber 207, second focus on coupled lens 208,
Polarization beam apparatus 210 and balanced detector 211.A tank 213 is placed in the lower section of acoustical signal detector 102, and object under test 103 is put
Lower section in tank 213.
Laser instrument 201 is used for producing continuous laser.
Wave plate 202 is placed in the front of laser instrument 201, and for by continuous laser furnishing rotatory polarization, this wave plate 202 can be four
/ mono-wave plate.
First focuses on coupled lens 203 is placed in the front of wave plate 202, for rotatory polarization is focused coupling.
Second single-mode fiber 204 is placed in the front of the first focusing coupled lens 203, swashing continuously after focusing on coupling
Light is transmitted.The laser of the second single-mode fiber 204 exports from fiber port 217.Light will be coupled into by continuous laser
Fine, it is achieved fiber-optic transfer, focus on the surface of acoustical signal detector 102.
First, second collimation bonder 205,206 is placed in the both sides of acoustical signal detector 102.First collimation bonder 205
For collimation coupling will be carried out from the second single-mode fiber 204 light out.Second collimation bonder 206 will be for visiting from acoustical signal
Survey in device 102 after light out carries out collimation coupling and export the 3rd single-mode fiber 207.
3rd single-mode fiber 207 collimates bonder 206 reflection light out for transmission from second.3rd single-mode fiber
The laser of 207 exports from fiber port 216.In detection light path, utilize the second single-mode fiber the 204, the 3rd single-mode optics
Fine 207 and first, second collimate bonder 205,206 carries out coupled transfer, and fiber-optic transfer makes continuous laser have stability,
Thus ensure that in platform scanner imaging process, optical signal includes catoptric micro objective 101 harmony in the core of system
Signal sensor 102 is not changed in, thus ensures to realize photoacoustic imaging under the conditions of homogeneous.
Second focuses on coupled lens 208 for reflection light is focused coupling.
The polarization beam apparatus 210 reflection light after being focused coupling is split, and is divided into P polarization light and S-polarization
Light.
After balanced detector 211 is placed in polarization beam apparatus 210, for detecting P polarization light and the variations in refractive index of S-polarization light
Amount.
Detection optical path component can also include that plane mirror 209, plane mirror 209 are placed in the side of polarization beam apparatus, is used for adjusting
The whole direction from polarization beam apparatus 210 S-polarization light out.
Continuous laser is modulated into rotatory polarization through quarter-wave plate 202, focuses on coupled lens 203 through first and focuses on coupling
Close, utilize the second single-mode fiber 204 to be transmitted, incide the surface of bench-type prism, utilize total internal reflection, detect the anti-of HONGGUANG
Penetrating optical signal, reflection light transmits through the 3rd single-mode fiber 207 again, and second focuses on coupled lens 208 focuses on coupling, polarization beam splitting
Device 210 is divided into P polarization and S-polarization two parts light, utilizes balanced detector 211 to detect P-polarization component and S-polarization in circularly polarized light
The intensity difference of component, it is achieved the measurement of the variations in refractive index of bench-type prism surface, by the P in detection altogether light path and S-polarization light
The intensity of component realizes Differential Detection, can effectively reduce environmental disturbances, including the instability of laser instrument, environmental vibration, temperature
The impact of the factors such as degree change, improves the detection sensitivity of system.
Acoustic pressure detector also includes imaging device 212, controls data card 215 and three-dimensional platform, and imaging device 212 is according to flat
The refractive index variable quantity that weighing apparatus detector 211 detects generates the photoacoustic imaging axonometric chart of object under test, and this imaging device can be
Desktop computer, notebook computer etc..This three-dimensional platform can be three-D electric platform, can also be three-dimensional manual platform.Reflection
The devices such as formula microcobjective 101, acoustical signal detector 102 are fixedly arranged on three-D electric platform.The light of dotted line frame 214 part in figure
Learn device catoptric micro objective 101, acoustical signal detector 102, planar light device 109, plane mirror the 110, first collimation coupling
Device 205, second collimates bonder 206 and tank 213 all can be fixedly arranged on three-D electric platform.Control data card 215 and become
As device 212 connects, for controlling the high precision movement of three-dimensional platform, and control tunable laser 104 and balance detection
Device 211, to guarantee the synchronization between three-dimensional platform, tunable laser 104 and balanced detector 211.Imaging device 212 is also used
In paired domination number according to storing and analyzing.Photoacoustic imaging is realized, this three-D electric by the 3-D scanning of three-D electric platform
Platform has the advantage that sweep limits is big, it is adaptable to biological thick sample, the photoacoustic imaging of biopsy samples.
During photoacoustic imaging, object under test 103 is placed on below scanning platform, and object under test 103 can be live body
Tissue sample.Utilize three-D electric platform scanner, it is achieved light focusing illumination is at the different parts of object under test 103, when pulse swashs
Light is reflected formula microcobjective 101 focusing and excites object under test 103, produces photoacoustic signal, optoacoustic owing to object under test 103 absorbs
Signals reverse is transferred into tank 213 and is transmitted to the surface of acoustical signal detector 102 through water, causes the faint change of surface refractive index
Change, because pulsed optical signals will not cause the change of surface refractive index, therefore can be obtained by the change of detection surface refractive index
To definite photoacoustic signal.Due to acoustical signal detector 102 different parts light absorbed and differ, varying strength can be produced
The photoacoustic signal of sound spectrum.The photoacoustic signal of varying strength causes the change of surface refractive index size, the photoacoustic signal of different sound spectrums
Also the time response that can cause variations in refractive index is different.Utilize acoustical signal detector 102 detect refractive index size variation amount and time
Between response characteristic, such that it is able to analyze the material composition of object under test 103.Utilizing three-dimensional platform, longitudinal scanning can realize
The detection of different depth object under test 103, transversal scanning realizes the detection of object under test 103 in same depth plane, and imaging divides
Resolution is determined with photoacoustic signal detection spectrum width by three-dimensional platform precision, is combined by the scanning information of object under test 103 different parts
Just can realize a secondary complete photoacoustic imaging axonometric chart.As shown in Figure 4, record for acoustical signal detector based on surface wave
Photoacoustic signal schematic diagram, as it is shown in figure 5, the light detected for employing acoustical signal detector based on surface wave of the present utility model
Acoustical signal spectrum scope schematic diagram.
The reflecting light sonomicroscope of acoustic pressure detector based on surface wave can be divided into excitation light path assembly and detection light
Road assembly, excitation light path part mainly by tunable laser 104, diaphragm 105, expand device 106, focus on coupled lens 107
With the first composition such as single-mode fiber 108 optics such as grade, detection light path part is mainly focused on by laser instrument 201, wave plate 202, first
Coupled lens the 203, second single-mode fiber 204, first collimates bonder 205, second and collimates bonder the 206, the 3rd single-mode fiber
207, second the optics compositions such as coupled lens 208, polarization beam apparatus 210 and balanced detector 211 are focused on.
Pulse laser in excitation light path from tunable laser 104 out, through diaphragm, expands, and optical fiber couples, single mode
Fiber-optic transfer, plane mirror is reflected into catoptric micro objective 101.Pulse laser is through the reflective micro-thing of high-NA
Mirror 101 focuses on and excites object under test 103, utilizes the broadband ultrasonic wave (i.e. photoacoustic signal) that transient heat buoyancy effect produces, and uses
Pulsed light excites, and is owing to acoustical signal is a wide range signal, can be by detecting the time response of photoacoustic signal, when utilizing
Territory-frequency domain mutation analysis, obtains the whole wide range information of photoacoustic signal.Incident laser will have significant portion absorbed or pass through
Object under test 103, if object under test 103 belongs to thin layer or transparent body laser can pass through, its reflection ratio is less, and produces
Photoacoustic signal substantially belong to each to symport, by the photoacoustic signal of detection light path detection reverse transfers, maximum advantage
It it is the interference that can avoid the laser in excitation light path, it is possible to achieve the detection of live body thickness sample.In detection light path, continuous laser
Being modulated into rotatory polarization through quarter wave plate 202, line focus couples, and utilizes single-mode fiber to transmit, incides desk-top prism surface, profit
With total internal reflection, the reflected light signal of detection HONGGUANG, reflection light line focus coupling, the 3rd single-mode fiber 207 transmits, polarization beam splitting
Device 210 is divided into P polarization and S-polarization two parts light, utilizes balanced detector 211 to detect P-polarization component and S-polarization in circularly polarized light
The intensity difference of component, it is achieved the measurement of the variations in refractive index of bench-type prism surface, by the P in detection altogether light path and S-polarization light
The intensity of component realizes Differential Detection, can effectively reduce environmental disturbances, improves the detection sensitivity of system.Due to bench-type rib
The surface of mirror or the fibre core 303 cross section metal-coated films of single-mode fiber 301 or graphene film, can increase by surface further
The reflex strength of two kinds of polarized light components that faint variations in refractive index causes is poor, plays the effect amplifying signal, improves detection spirit
Sensitivity.As shown in Figure 6, for using the reflecting light sonomicroscope of acoustical signal detector based on surface wave to detect the human body obtained
The photoacoustic imaging schematic diagram of hair sample.
The reflecting light sonomicroscope of acoustical signal detector based on surface wave of the present utility model uses reflective micro-
Laser gathering is irradiated on object under test 103 by object lens so that object under test 103 absorbs laser and produces photoacoustic signal, then
Acoustical signal detector 102 is used to detect the photoacoustic signal that refraction occurs through medium transmission again, and according to the photoacoustic signal after refraction
Generate the detection spectrum of object under test.In this utility model, optical surface ripple sensing technology uses the method for optical sensing refractive index in fact
Existing, there is label-free, contactless sensing detection feature, can be widely applied to cell and molecular level detection.Due to any
Small change and effect the most easily cause the change of refractive index, and the solution refractive index that therefore acoustic vibration causes slightly changes also
Can be detected by optical surface ripple.Surface wave all has superiority at aspects such as acoustic detection bandwidth, sensitivity: surface wave propagation away from
From short, time response is fast, within generally 1ns, it is possible to achieve higher detective bandwidth；And the small change of surface wave refractive index
Change and have superpower sensitivity, it is possible to achieve the detectivity of 10Pa level；Simultaneously as surface wave is special to the response of different polarization
Property, utilize polarization differential method that signal contrast can be greatly improved.
The foregoing is only preferred embodiment of the present utility model, not in order to limit this utility model, all at this
Any amendment, equivalent and the improvement etc. made within the spirit of utility model and principle, should be included in this utility model
Protection domain within.
Claims (13)
1. an acoustical signal detector based on surface wave, it is characterised in that include the rib with two planes being parallel to each other
Mirror, described in a plane in two planes being parallel to each other be coated with thin film, described thin film for detection through the light of medium transmission
Acoustical signal.
Acoustical signal detector the most according to claim 1, it is characterised in that described thin film be metallic film or Graphene thin
Film.
3. an acoustical signal detector based on surface wave, including multimode fibre, it is characterised in that described multimode fibre includes bag
Layer and the fibre core being placed in covering, it is parallel with described multimode fibre length bearing of trend that the fibre core of described multimode fibre has one
Cross section, described covering has a breach making described cross section be exposed to outside described covering, and described cross section is positioned at described indentation, there, institute
Stating and be coated with thin film on cross section, described thin film is for detecting the photoacoustic signal through medium transmission.
Acoustical signal detector the most according to claim 3, it is characterised in that described thin film be metallic film or Graphene thin
Film.
5. the reflecting light sonomicroscope of an acoustic pressure detector based on surface wave, it is characterised in that include reflective micro-
Object lens harmony signal sensor；
Described catoptric micro objective is placed in the top of described acoustical signal detector, shines for the laser focusing launched by lasing light emitter
It is mapped on object under test so that described object under test absorbs described laser and produces photoacoustic signal, and described photoacoustic signal reversely passes
Defeated after the medium above object under test reflects, enter described acoustical signal detector；
Described acoustical signal detector is placed in the top of described object under test and is positioned at the lower section of described catoptric micro objective, is used for
Detect through the photoacoustic signal of medium transmission, and according to described photoacoustic signal generate object under test for making object under test imaging
Detection spectrum.
Reflecting light sonomicroscope the most according to claim 5, it is characterised in that described acoustical signal detector is for put down up and down
Face is parallel and lower plane is coated with the prism of thin film or is coated with the multimode fibre of thin film, and described thin film is for detecting through medium transmission
Photoacoustic signal；
Described multimode fibre include covering and the fibre core being placed in covering, the fibre core of described multimode fibre have one with described multimode
The cross section that fiber lengths bearing of trend is parallel, described covering has a breach making described cross section be exposed to outside described covering, institute
Stating cross section and be positioned at described indentation, there, described thin film is plated on described cross section.
Reflecting light sonomicroscope the most according to claim 5, it is characterised in that described reflecting light sonomicroscope also wraps
Include excitation light path assembly and detection optical path component；
Described excitation light path assembly focuses on described object under test for emission pulse laser, to excite object under test to produce light
Acoustical signal；
Described detection optical path component is used for sending continuous laser and incides to carry out total internal reflection on described acoustical signal detector, and
The variations in refractive index of detection reflected light signal after total internal reflection.
Reflecting light sonomicroscope the most according to claim 7, it is characterised in that described excitation light path assembly includes adjustable
Humorous laser instrument, diaphragm, expand device, focus on coupled lens and the first single-mode fiber；
Described tunable laser is used for producing pulse laser；
Described diaphragm is placed in the front of described tunable laser, for adjusting the beam size of pulse laser；
The described device that expands is for being enlarged from the light beam of described diaphragm pulse laser out；
Described focusing coupled lens expands the front of device described in being placed in, for being gathered by the pulse laser expanded through light beam
Burnt coupling；
Described first single-mode fiber is placed in the front of described focusing coupled lens, and the pulse laser after focusing on coupling transmits
On described catoptric micro objective.
Reflecting light sonomicroscope the most according to claim 8, it is characterised in that described excitation light path assembly also includes putting down
Face electro-optical device and plane mirror；
Described planar light device is placed in the front of described single-mode fiber, for being expanded by the lasing light emitter of described first single-mode fiber output
Restraint into directrix plane light；
Described plane mirror is placed in the front of described planar light device, makes pulse laser to enter for changing the direction of pulse laser
On described catoptric micro objective.
Reflecting light sonomicroscope the most according to claim 7, it is characterised in that described detection optical path component includes swashing
Light device, wave plate, the first focusing coupled lens, the second single-mode fiber, the first collimation bonder, the second collimation bonder, the 3rd list
Mode fiber, the second focusing coupled lens, polarization beam apparatus and balanced detector；A water is placed in the lower section of described acoustical signal detector
Groove, described object under test is placed in the lower section of described tank；
Described laser instrument is used for producing continuous laser；
Described wave plate is placed in the front of described laser instrument, for by described continuous laser furnishing rotatory polarization；
Described first focuses on coupled lens is placed in the front of described wave plate, for rotatory polarization is focused coupling；
Described second single-mode fiber is placed in the described first front focusing on coupled lens, for focusing on the continuous laser after coupling
It is transmitted；
Described first, second collimation bonder is placed in the both sides of described acoustical signal detector, and described first collimation bonder is used for
To carry out collimation coupling from described second single-mode fiber light out, described second collimation bonder is for will be from described acoustical signal
After in detector, light out carries out collimation coupling, output is to described 3rd single-mode fiber；
Described 3rd single-mode fiber collimates bonder reflection light out for transmission from described second；
Described second focuses on coupled lens for described reflection light is focused coupling；
Described polarization beam apparatus reflection light after being focused coupling is split, and is divided into P polarization light and S-polarization light；
After described balanced detector is placed in described polarization beam apparatus, for detecting described P polarization light and the refraction of described S-polarization light
Rate variable quantity.
11. reflecting light sonomicroscopes according to claim 10, it is characterised in that described detection optical path component includes putting down
Face mirror, described plane mirror is placed in the side of polarization beam apparatus, for adjusting the side from described polarization beam apparatus S-polarization light out
To.
12. reflecting light sonomicroscope according to claim 10, it is characterised in that described acoustic pressure detector also includes into
As device, the optoacoustic that described imaging device generates object under test according to the refractive index variable quantity that described balanced detector detects becomes
As axonometric chart.
13. reflecting light sonomicroscopes according to claim 5, it is characterised in that described reflecting light sonomicroscope is also
It is fixedly arranged on three-D electric platform including three-D electric platform, described catoptric micro objective and described acoustical signal detector.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106092901A (en) * | 2016-06-07 | 2016-11-09 | 深圳大学 | A kind of acoustical signal detector based on surface wave and reflecting light sonomicroscope |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106092901A (en) * | 2016-06-07 | 2016-11-09 | 深圳大学 | A kind of acoustical signal detector based on surface wave and reflecting light sonomicroscope |
| CN106092901B (en) * | 2016-06-07 | 2019-04-30 | 深圳大学 | A kind of acoustical signal detector and reflecting light sonomicroscope based on surface wave |
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