CN205821323U - A kind of thrombin flat panel filter device - Google Patents

A kind of thrombin flat panel filter device Download PDF

Info

Publication number
CN205821323U
CN205821323U CN201620729911.2U CN201620729911U CN205821323U CN 205821323 U CN205821323 U CN 205821323U CN 201620729911 U CN201620729911 U CN 201620729911U CN 205821323 U CN205821323 U CN 205821323U
Authority
CN
China
Prior art keywords
filter
thrombin
flat panel
plate
filter device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201620729911.2U
Other languages
Chinese (zh)
Inventor
方伟国
徐新胜
付存雷
李倩
吴倩倩
柯益娜
卢文义
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Hangzhou Pharmaceutical Co Ltd
Original Assignee
Zhejiang Hangzhou Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Hangzhou Pharmaceutical Co Ltd filed Critical Zhejiang Hangzhou Pharmaceutical Co Ltd
Priority to CN201620729911.2U priority Critical patent/CN205821323U/en
Application granted granted Critical
Publication of CN205821323U publication Critical patent/CN205821323U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

The utility model discloses a kind of thrombin flat panel filter device, including supporting seat, being fixed on the filtering table and closing cap lid on filtering table supported on seat, it is characterized in that, described filtering table is built-in with plate filter plate, being the agent structure with filter opening bottom this filter plate, end face is the supporting layer of hollow out.The thrombin flat panel filter device that this utility model carries, use double-deck filter-plate structure, uniform support force is provided to filter paper or filter membrane, avoid at filter opening due to powerful pressure reduction, filter paper or filter membrane is caused to wear and tear at filter opening, ensure that filters is smoothed out, it is ensured that filter quality, improve filter efficiency.

Description

A kind of thrombin flat panel filter device
Technical field
This utility model relates to a kind of defecator, is specifically related to a kind of thrombin flat panel filter device.
Background technology
Thrombin is a kind of serine protease, is also the main effects protease in blood coagulation cascade reaction, manifests Go out the characteristic of coagulant and anticoagulant.Thrombin is at Xa factor (FXa) by the nonactive thrombinogen in prothrombin complex Produce by the way of protein cleavage under the effect of the factor.When circulation thrombin is at the extravascular tissue exposed and tissue factor When contacting, thrombin can be assembled organizationally.Thrombin is by activating platelet, and catalysis fibre proteinogen is converted into fiber egg In vain, promote that clot is stable.
Thrombinogen can extract from animal or human blood, generally comprises: animal blood is centrifuged by (1), obtains Obtain blood plasma;(2) utilize gel adsorption, adsorb thrombinogen therein;(3) thrombinogen of eluting absorption, obtains thrombinogen; (4) activate thrombinogen and obtain thrombin solution;(5) the thrombin lyophilized powder of the i.e. available white of multiple times of filtration purification, lyophilizing.
Such as during the patent documentation of Application No. CN 201410454654.1 the discloses a kind of Sanguis Leporis seu oryctolagi purification system of thrombin Preparation Method, mainly comprises the technical steps that: (1) Sanguis Leporis seu oryctolagi pre-treatment;(2) filter liquor desalination;(3) activation of rabbit thrombin;(4) Heparin affinity chromatograph;(5) purification of rabbit thrombin.
The patent documentation of Application No. CN201310112769.8 discloses the preparation method of a kind of pig thrombiase, including: One, porcine blood plasma is separated;Two, chemical method inactivation of virus;Three, absorption thrombinogen;Four, thrombinogen is collected;Five, nanofiltration; Six, the activation of thrombinogen;Seven, the lyophilizing of thrombin preserves.
In multiple times of filtration purge process, use various defecator, but existing defecator, due to sucking filtration power relatively Greatly, easily cause filter membrane to damage.
Utility model content
This utility model provides a kind of thrombin flat panel filter device, will not damage filter paper or filter membrane, reduce solidifying The filtration cost of hemase, improves filter efficiency.
A kind of thrombin flat panel filter device, including supporting seat, being fixed on the filtering table and closing cap supported on seat Lid on filtering table, described filtering table is built-in with plate filter plate, is the agent structure with filter opening bottom this filter plate, top Face is the supporting layer of hollow out.
The setting of supporting layer, provides uniform support force to filter paper or filter membrane, it is to avoid due to powerful pressure reduction at filter opening, Cause filter paper or filter membrane to wear and tear at filter opening, it is ensured that being smoothed out of filtration, it is ensured that filter quality, improve filtration effect Rate.
As preferably, described supporting layer is made up of the concentric ring bar being attached to agent structure end face.Concentric ring bar structure, enters One step enhances support effect, will not hinder the carrying out of filtration simultaneously.
As preferably, described plate filter plate is circular, and each concentric ring bar is along the radially uniform setting of plate filter plate.
As preferably, the width of described concentric ring bar less than 1/3rd of filter opening diameter, adjacent two concentric ring bars it Between be smaller than filter opening diameter.Use the program, it is ensured that have the supporting role of concentric ring bar in each filter opening, ensure simultaneously Integral filter efficiency, it is to avoid concentric ring bar hides filter opening.As further preferably, the width of described concentric ring bar be 0.5~ 2mm;A diameter of the 3 of described filter opening~6mm.
As preferably, described agent structure and supporting layer are integrated metal structure.Use this structure, it is possible to ensure The bulk strength of filter plate.
As preferably, described lid center is provided with charging aperture, and described lid inwall center is provided with for the position of charging aperture Distributor.The setting of distributor makes material more uniformly enter filter plate surface to filter.
As preferably, described filtering table center is provided with the sunk structure of back taper bench-type, and this sunk structure side wall surface is provided with Top-down guiding gutter, sunk structure center is discharge opening.Sunk structure is used for collecting filtrate, and guiding gutter ensures that filtrate is quick The smooth and easy sunk structure content that enters into, finally from discharge opening discharging.
The thrombin flat panel filter device that this utility model carries, uses double-deck filter-plate structure, provides filter paper or filter membrane Uniform support force, it is to avoid due to powerful pressure reduction at filter opening, cause filter paper or filter membrane to wear and tear at filter opening, it is ensured that filtration It is smoothed out, it is ensured that filter quality, improves filter efficiency.
Accompanying drawing explanation
Fig. 1 is the structural representation of the thrombin flat panel filter device that this utility model carries.
Fig. 2 is the plan structure schematic diagram of filtering table.
Fig. 3 is filter plate partial enlarged drawing at A in Fig. 2.
Detailed description of the invention
As shown in Figures 1 to 3, a kind of thrombin flat panel filter device, including supporting seat 601, being fixed on support seat 601 Filtering table 602 and the closing cap lid 603 on filtering table, filtering table is built-in with plate filter plate 604, bottom this filter plate For the agent structure 605 with filter opening 608, end face is the supporting layer 606 of hollow out.
Supporting layer 606 is made up of the concentric ring 607 being attached to agent structure end face.Plate filter plate 604 is circular, respectively Individual concentric ring 607 is along the radially uniform setting of plate filter plate.The width that concentric ring is 607 is less than three points of filter opening 608 diameter One of, it is smaller than filter opening diameter between adjacent two concentric ring bars.The support of concentric ring bar is had in ensureing each filter opening Effect, ensure that integral filter efficiency simultaneously, it is to avoid concentric ring bar hides filter opening.As a kind of specific embodiment, with one heart The width that ring is 607 is 0.5~2mm;A diameter of the 3 of filter opening 608~6mm.The setting of supporting layer 606, to filter paper or filter membrane There is provided uniform support force, it is to avoid due to powerful pressure reduction at filter opening, cause filter paper or filter membrane to wear and tear at filter opening, it is ensured that mistake Being smoothed out of filter, it is ensured that filter quality, improves filter efficiency.Agent structure 605 and supporting layer 606 are integrated Metal structure.Use this structure, it is possible to ensure the bulk strength of filter plate.Add man-hour, directly use lathe process to form.
Lid 603 center is provided with charging aperture 609, and lid inwall center is provided with distributor 610 for the position of charging aperture.Point Cloth device 610 surrounding is uniformly provided with multiple discharge opening, and the setting of distributor makes material more uniformly enter filter plate surface to enter Row filters.The position that lid 603 docks with filter disc 602 is provided with sealing gasket 611, close with ensure between lid 603 and filter disc 602 Feng Xing.
Filter disc 602 center is provided with the sunk structure 612 of back taper bench-type, and this sunk structure side wall surface is provided with top-down Guiding gutter, sunk structure center is discharge opening 613.Sunk structure is used for collecting filtrate, guiding gutter ensure filtrate the most smooth and easy enter Enter to sunk structure content, finally from discharge opening discharging.
It is simultaneously provided with the conventional structures such as gas vent on filter disc 602.When actual motion, realize lid 603 by stud 614 And fixing between filter disc 602, opens material inlet valve, and high pressure feed liquid enters into plate filter plate 604 through charging aperture 609 and carries out Filtering, filter paper or filter membrane, under supporting layer 606 supporting role, will not be damaged, and filtrate collects Sheng through discharge opening 613 Put in container.

Claims (8)

1. a thrombin flat panel filter device, exists including supporting seat, the filtering table being fixed on support seat and closing cap Lid on filtering table, it is characterised in that described filtering table is built-in with plate filter plate, is the master with filter opening bottom this filter plate Body structure, end face is the supporting layer of hollow out.
Thrombin flat panel filter device the most according to claim 1, it is characterised in that described supporting layer is by being attached to main body The concentric ring bar composition of structure end face.
Thrombin flat panel filter device the most according to claim 2, it is characterised in that described plate filter plate is circular, Each concentric ring bar is along the radially uniform setting of plate filter plate.
Thrombin flat panel filter device the most according to claim 2, it is characterised in that the width of described concentric ring bar is less than / 3rd of filter opening diameter, are smaller than filter opening diameter between adjacent two concentric ring bars.
Thrombin flat panel filter device the most according to claim 2, it is characterised in that described agent structure and supporting layer are Integrated metal structure.
Thrombin flat panel filter device the most according to claim 1, it is characterised in that described lid center is provided with charging Mouthful, described lid inwall center is provided with distributor for the position of charging aperture.
Thrombin flat panel filter device the most according to claim 1, it is characterised in that described filtering table center is provided with back taper The sunk structure of bench-type, this sunk structure side wall surface is provided with top-down guiding gutter, and sunk structure center is discharge opening.
8. according to the thrombin flat panel filter device described in claim 2 or 4, it is characterised in that the width of described concentric ring bar It is 0.5~2mm;A diameter of the 3 of described filter opening~6mm.
CN201620729911.2U 2016-07-07 2016-07-07 A kind of thrombin flat panel filter device Active CN205821323U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620729911.2U CN205821323U (en) 2016-07-07 2016-07-07 A kind of thrombin flat panel filter device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620729911.2U CN205821323U (en) 2016-07-07 2016-07-07 A kind of thrombin flat panel filter device

Publications (1)

Publication Number Publication Date
CN205821323U true CN205821323U (en) 2016-12-21

Family

ID=57565390

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201620729911.2U Active CN205821323U (en) 2016-07-07 2016-07-07 A kind of thrombin flat panel filter device

Country Status (1)

Country Link
CN (1) CN205821323U (en)

Similar Documents

Publication Publication Date Title
US20100288691A1 (en) Porous filter cartridge
CN100404101C (en) Active carbon fabric composite filter element and production method thereof
JP2013155187A (en) Method for purifying biomolecule from mixture containing impurity
CN110420569A (en) A kind of bionic catalysis film and its preparation method and application
CN101277746B (en) Single pass method and apparatus for separating a target molecule from a liquid mixture
CN108126522A (en) The method of target particles in separating chips, separator and separation liquid sample
CN205821323U (en) A kind of thrombin flat panel filter device
JPH11237378A (en) Method for separating serum from whole blood
JP6143746B2 (en) Nucleated cell capture filter or nucleated cell preparation method using the same
CN101469321A (en) Method for rapidly filtering and screening medulla ossium substrate stem cell
CN102361658A (en) Sorbent for removing protein-bound substances
CN106622193A (en) Resin collecting and washing system
US11874209B2 (en) Isolation device and isolation method for isolating target particles from liquid samples
KR20160138403A (en) Enhancement of recombinant protein expression using a membrane-based cell retention system
CN202683355U (en) Centrifugal tube for multistage purification
CN206045805U (en) A kind of hollow fiber film assembly casting box
CN214300076U (en) Membrane carrier purification device for biological particles
JPH0341965A (en) Fibrin gel containing oxygen active sub- stance
JP2007240304A (en) Fractionation apparatus
CN212998748U (en) Closed autologous bone marrow mononuclear cell and platelet centrifugal filtering enricher
CN205821324U (en) A kind of fixing device of fixing thrombin filter membrane bag
CN209048767U (en) A kind of stem cell in vitro enrichment isolation system
CN205821352U (en) A kind of thrombin sterilization filter device
CN106745459B (en) The adsorpting regenerating process of dyestuff in a kind of disperse dyestuff waste water
CN112251320A (en) Biological particle purification device and purification method

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant