CN205795728U

CN205795728U - Saliva sample harvester

Info

Publication number: CN205795728U
Application number: CN201620459171.5U
Authority: CN
Inventors: 张春秀; 滕晓坤
Original assignee: SHANGHAI BIOTECHNOLOGY Corp
Current assignee: SHANGHAI BIOTECHNOLOGY Corp
Priority date: 2016-05-19
Filing date: 2016-05-19
Publication date: 2016-12-14
Anticipated expiration: 2026-05-19

Abstract

The utility model discloses a kind of saliva sample harvester, including: gather pipe cap, gather funnel, guarantor's liquid storing tube and collection tube；Described collection funnel lower end is provided with sharp projection；Described guarantor's liquid storing tube top uses and can puncture material seal, protects the external diameter internal diameter less than collection tube of liquid storing tube, and height is less than collection tube；Described collection pipe cap, collection funnel are flexibly connected with collection tube respectively.This utility model, by improving the structure of saliva sample harvester, makes the more convenient health of saliva sample harvester and is readily transported.

Description

Saliva sample harvester

Technical field

This utility model relates to biology field, particularly relates to a kind of saliva sample harvester.

Background technology

Departing from cell containing oral mucosa in human saliva, gather saliva carrying out molecular biological analysis is that fanout free region takes Sample, simple and easy to do, therefore it is generally used.Existing acquisition method has cotton swab acquisition method, scraping blade acquisition method etc., these sides Method, in addition to complex operation, usually also needs to cotton swab or scraping blade are put into oral cavity, with oral contact, so easily produces Raw pollution or injury.

After general saliva has gathered, need to put into preservation liquid, and preserve liquid mixing, in order to preserve its amplifying nucleic acid, albumen The original form of the material such as matter, cell, carries out subsequent detection analysis.Therefore saliva should mix with preservation liquid after acquisition as early as possible, Accordingly, the multiple device gathered for saliva and instrument are had been developed for.

Patent No. ZL200620123835.7, the Chinese utility model patent of entitled " double head saliva collector ", public Having opened a kind of double head saliva collector, it is made up of threaded sampling rod, cylinder-form main tube and outlet lid three part.Sampling Rod is made up of cotton three structures of upper cover, plunger and imbibition.During sampling, sampling rod imbibition cotton end is put in mouth so that it is be stained with saliva Liquid sample, then sampling rod is reentered into cylinder-form main tube, tighten bottle cap, turn on out sample lid, squeeze out sample.Gather with imbibition cotton Sample, easily pollutes, and complex operation.

Patent No. ZL201020215405.4, the Chinese utility model patent of entitled " saliva collecting device ", its saliva Liquid harvester includes collection tube and the collection tube gag matched with collection tube, also includes and the collection of collection tube pivot bush unit Funnel.Saliva fixative is directly installed in collection tube, seals with collection tube gag.When gathering saliva, funnel lower end will be gathered Inserting collection tube, the saliva of saliva supplier flows into collection tube through funnel, is removed by collection funnel, covers tightly collection tube gag, will Collection tube turns upside down for several times, saliva is mixed homogeneously with fixative, and collection tube loads the valve bag that this harvester is subsidiary. When this way is saliva collection, nucleic acid stability agent is in open state, it is easy to polluted by foreign substances, simultaneously also can be to human body Produce and pollute.If the nucleic acid stability agent used is prone to volatilization, then the abnormal smells from the patient produced can affect human body.It addition, reagent volatilization If, amount of reagent can be caused to reduce, saliva mixes uneven with reagent, the inconvenience such as leakage during use.

Also have and individually do filler cap, nucleic acid stability agent is deposited in filler cap, such as the product of Oragene DNA, but In use, easily before not gathering saliva at the beginning, the lid preserving nucleic acid stability agent is crushed, there is no safeguard procedures.Patent Number be ZL201120449083.4, the Chinese utility model patent of entitled " saliva DNA harvester ", have employed with The method that the OG-500 that Oragene DNA produces is similar, is placed on stabilizer inside lid, after sample collection, by screwing lid Thin film on lid is crushed by the process of son, makes stabilizer carry out, in pipe, mixing with sample.So there is also and Oragene mono- The problem of sample, i.e. lid do not have safeguard procedures, crush the most before use.But this harvester in use still needs to leak collection Bucket installation and removal, pollute probability relatively big, use inconvenience, have much room for improvement.

Application No. CN201510451771.7, entitled " a kind of saliva gather and saliva liquid volume measurement apparatus and method " Chinese utility model patent application, the problem one existed is that when using, needs are centrifuged, because saliva typically compares thickness, is difficult to logical Small holes；Two is that lid seals poor with body, is not easy to the transport of sample, can only be to use after acquisition at once.

Application No. CN201510265125.1, the Chinese utility model patent of entitled " saliva DNA gathers and preserves bottle " Application, have employed multiple valve structure, it is therefore an objective to protection sample is not contaminated, but, sample flowing between multiple valve needs By aperture, typically comparing thickness due to saliva, despite guiding gutter, saliva is also easily detected by, and is namely difficult to stable Reagent mixes.

Application No. CN201510801563.5, the Chinese utility model patent Shen of entitled " a kind of saliva collecting device " Please, have employed multistage attachable result, one-level one-level is directly threaded connection.Preserve liquid and be placed in the pipe of bottommost in advance In, protect with isolating membrane；Top is saliva collection tube, and the two employing is threaded, is easily generated seepage.

Title is respectively " a kind of spittle collector " (application number CN201610032214.6), " a kind of saliva gathers and saliva Liquid volume measurement apparatus and method " (application number CN201510451771.7), and " saliva DNA gathers and preserves bottle " (application number CN201510265125.1) Chinese utility model patent application, adds steam vent on saliva collector surface, but for The such dope of saliva, the effect of this small de-air hole is the faintest.

Utility model content

The technical problems to be solved in the utility model is to provide a kind of saliva sample harvester, its simple in construction, conveniently defends Raw.

For solve above-mentioned technical problem, saliva sample harvester of the present utility model, including: gather pipe cap, gather funnel, Protect liquid storing tube and collection tube；Described collection funnel lower end is provided with sharp projection；Described guarantor's liquid storing tube top uses can puncture material Material seals, and protects the external diameter internal diameter less than collection tube of liquid storing tube, and height is less than collection tube；Described collection pipe cap, collection funnel divide It is not flexibly connected with collection tube.

It is also preferred that the left described collection tube hatband has rubber seal, with guarantee saliva gather after salable transhipment or storage.

It is also preferred that the left described collection funnel is with limit buckle, puncture preservation with the projection below funnel before preventing collection saliva The sealing of liquid pipe.

Described collection pipe cap, the connection gathered between funnel and collection tube can use and threaded.

Compared with existing saliva sample DNA harvester, saliva sample collection equipment of the present utility model have the advantage that and Beneficial effect:

1, simple in construction, good looking appearance, compact, it is simple to transport；

2, painless collection, does not have invasive, and gathered person is without any discomfort sense, convenient and healthy；

3, preservation liquid is deposited in collection tube, and by plastic sheeting/foil sealing, it is simple to process operation, and in transport During be difficult to puncture, it is simple to transport；

4, gather funnel envisaged underneath limited location button, be possible to prevent to puncture following gathering before saliva the projection below funnel The sealed membrane protecting liquid storing tube, so that it is guaranteed that only when saliva gathers, tearing after limit buckle could the sealer of guarantor's liquid storing tube Puncture.

Accompanying drawing explanation

Fig. 1 is the structural representation gathering pipe cap of the saliva sample harvester of the present embodiment；

Fig. 2 is the structural representation gathering funnel of the saliva sample harvester of the present embodiment；

Fig. 3 is the structural representation protecting liquid storing tube of the saliva sample harvester of the present embodiment；

Fig. 4 is the structural representation of the collection tube of the saliva sample harvester of the present embodiment.

Fig. 5 is the overall structure schematic diagram of the saliva sample harvester of the present embodiment.

In figure, description of reference numerals is as follows:

1: gather pipe cap

2: gather funnel

3: protect liquid storing tube

4: collection tube

B1: limit buckle

B2: base projections

Detailed description of the invention

More specifically understand for technology contents of the present utility model, feature are had with effect, in conjunction with accompanying drawing and specifically real Execute example, this utility model is described in further detail.Embodiment is served only for illustrating this utility model, but is not limited to this The scope of utility model.

The saliva sample harvester of the present embodiment, including gathering pipe cap, gathering funnel, guarantor liquid storing tube, four portions of collection tube Being grouped into, overall structure is as shown in Figure 5.Gather pipe cap, collection funnel can be threadeded with collection tube respectively.Gather under funnel End has sharp projection, gathers funnel suitable altitudinal belt limited location button.There is preservation liquid in protecting liquid storing tube, preserve liquid pipe plastic thin The material seal that film/aluminium foil etc. can puncture, and protect the external diameter internal diameter less than collection tube of liquid storing tube, height is less than collection tube.Adopt Collector hatband has rubber seal, with guarantee saliva gather after salable transhipment or storage.

Before using, instrument is utilized to be positioned over bottom collection tube by guarantor's liquid storing tube of sealing.Gather funnel to pass through with collection tube Threaded, gather funnel envisaged underneath limited location button, the screw thread gathering funnel and collection tube is tightened onto to a certain degree.Collection tube Cap is independently placed.Now can carry out the transport of spittle collector and transfer.

Take out saliva sample harvester during use, tear the limit buckle gathered below funnel, the face alignment of gathered person Gathering funnel, saliva flows in collection tube by gathering funnel.After saliva has gathered, the spiral shell between funnel and collection tube will be gathered Stricture of vagina is tightened, and during tightening, the projection gathering funnel bottom will puncture the following encapsulant preserving the liquid mouth of pipe, gather Saliva flow into and protect in liquid storing tube, unclamp the screw thread gathering funnel with collection tube after completing, take off collection funnel, with gathering pipe cap Covering collection tube, tighten, prevent liquid from leaking, turn upside down guarantor's liquid storing tube, makes saliva uniformly mix with preserving liquid.

Change the preservation liquid protected in liquid storing tube, different types of biological specimen preservation can be carried out, as albumen preserve liquid, DNA preserves liquid, RNA preserves liquid, can carry out the preservation of sialoprotein, the preservation of saliva DNA, the preservation of saliva RNA respectively, full The demand of the different bioanalysis of foot.

Claims

1. saliva sample harvester, it is characterised in that including: gather pipe cap, gather funnel, guarantor's liquid storing tube and collection tube；Described Gather funnel lower end and be provided with sharp projection；Described guarantor's liquid storing tube top uses and can puncture material seal, protects the external diameter of liquid storing tube Less than the internal diameter of collection tube, height is less than collection tube；Described collection pipe cap, collection funnel are flexibly connected with collection tube respectively.

Saliva sample harvester the most according to claim 1, it is characterised in that described collection tube hatband has rubber seal Circle.

Saliva sample harvester the most according to claim 1, it is characterised in that described collection funnel is with limit buckle.

Saliva sample harvester the most according to claim 1, it is characterised in that described collection pipe cap, collection funnel are respectively Use with collection tube and threaded.