CN205709900U - A kind of18f NaF Fully automated synthesis device - Google Patents
A kind of18f NaF Fully automated synthesis device Download PDFInfo
- Publication number
- CN205709900U CN205709900U CN201521126548.7U CN201521126548U CN205709900U CN 205709900 U CN205709900 U CN 205709900U CN 201521126548 U CN201521126548 U CN 201521126548U CN 205709900 U CN205709900 U CN 205709900U
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- China
- Prior art keywords
- bottle
- naf
- valve
- fully automated
- automated synthesis
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Abstract
This utility model relates to one18F NaF Fully automated synthesis device, belongs to8F NaF Fully automated synthesis technical field；There is provided a kind of simple to operate, production efficiency is high, medicine concordance is good, cannot be easily caused radiation pollution18F NaF Fully automated synthesis device；Including 18F target, QMA post, waste liquid bottle, product bottle, aseptic water bottle, normal saline bottle and nitrogen cylinder etc., after 18F target Hong target, transmission18F also makes it adsorb on QMA post, and waste liquid enters in waste liquid bottle, then extraction 5mL aseptic water washing QMA post 45 seconds, utilizes 200CC nitrogen to dry up pipeline and QMA post, then extracts 5mL normal saline drip washing QMA post 45s, and finally transmission 150CCM nitrogen will18F NaF is transported in product bottle, and above procedure sets after parameter by computer full-automatic control；This utility model is mainly used in radiopharmaceutical Fully automated synthesis aspect.
Description
Technical field
This utility model relates to18F-NaF Fully automated synthesis technical field, more specifically, relates to one18F-NaF is automatic
It is combined to device.
Background technology
At present, preparation radioactivity positron medicine18The process of F-NaF is, first cyclotron Hong target is produced18F-is transferred to waste liquid bottle, dilutes with syringe18F-to 5mL, extracts this diluent liquid 5mL and crosses QMA post and make18F-adsorbs at QMA
On post, then extracting 10mL aseptic water flushing QMA post, finally extraction 10mL normal saline drip washing QMA post obtains18F-NaF, due to
Above procedure is manually, and the operating time is long, and production efficiency is low, is also easy to cause surrounding radioactive pollution and staff
Hand radiation dose is excessive.Therefore, it is necessary to make improvements.
Utility model content
In order to overcome the deficiency in the presence of prior art, it is provided that a kind of simple to operate, production efficiency is high, reduce work people
Member radiation dose, cannot be easily caused radiation pollution18F-NaF Fully automated synthesis device.
In order to solve above-mentioned technical problem, the technical scheme that this utility model is used is:
A kind of18F-NaF Fully automated synthesis device, including 18F target, QMA post, waste liquid bottle, product bottle, aseptic water bottle, physiology
Saline bottle and nitrogen cylinder, described 18F target is coupled with waste liquid bottle and product bottle respectively by QMA post, described aseptic water bottle, physiology salt
Water bottle and nitrogen cylinder couple with QMA post respectively, and described QMA post also couples radioactivity seeker.
Described 18F target is coupled with QMA post by V321 valve.
Described QMA post is coupled with waste liquid bottle by V317 valve, is coupled with product bottle by V316A valve.
Described aseptic water bottle, normal saline bottle and nitrogen cylinder are all coupled with QMA post by V320 valve.
Nitrogen valve it is provided with between described nitrogen cylinder and V320 valve.
Being provided with sterilized water syringe between described aseptic water bottle and V320 valve, described sterilized water syringe couples to be had
V318 valve.
Being provided with physiological saline device between described normal saline bottle and V320 valve, described physiological saline device joins
It is connected to V316B valve.
Described V321 valve, V317 valve, V316A valve, V320 valve, nitrogen valve, V318 valve, V316B valve
All controlled by computer.
Compared with prior art this utility model is had the beneficial effect that
This utility model realizes the automated production of device to be prepared, it is possible to set parameter by computer control, compared to existing
Manual production, simple to operate, production efficiency is high, and medicine quality consistency is good, has good economy, can effectively reduce people
Work cost, avoids the hand radiation injury of the radioactive pollution to surrounding and staff simultaneously, improves and produced
The safety of journey.
Accompanying drawing explanation
Below by accompanying drawing, detailed description of the invention of the present utility model is described in further detail.
Fig. 1 is process chart of the present utility model.
In figure: 1 be 18F target, 2 for QMA post, 3 for waste liquid bottle, 4 for product bottle, 5 for aseptic water bottle, 6 for normal saline bottle,
7 be nitrogen cylinder, 8 be radioactivity seeker, 9 be V321 valve, 10 be V317 valve, 11 be V316A valve, 12 for V320 valve
Door, 13 be nitrogen valve, 14 for sterilized water syringe, 15 for V318 valve, 16 for physiology saline syringe, 17 be V316B valve
Door.
Detailed description of the invention
Example below combines accompanying drawing, and the utility model will be further described.
As shown in Figure 1: the transmission line of 18F target 1 is accessed V321 valve 9, QMA post 2 is accessed seat shown in figure, treats
After 18F target 1 Hong target, open V321 valve 9 and V317 valve 10, transmission18F-And making it adsorb on QMA post 2, waste liquid is arranged
Enter in waste liquid bottle 3, stop transmission when the numeral on radioactivity seeker 8 no longer increases, then open V318 valve 15, aseptic
Water syringe 14 extracts 5mL sterilized water from aseptic water bottle 5, turns off V318 valve 15, sets when rinsing a length of 45 seconds and rinses
QMA post 2, then sets nitrogen cylinder 7 and transmits nitrogen as 200CCM, open nitrogen valve 13 and V320 valve 12, utilize nitrogen
Drying up pipeline and QMA post 2, then open V316B valve 17, it is raw that physiological saline device 16 extracts 5mL from normal saline bottle 6
Reason saline, closes V316B valve 45s, drip washing QMA post 2, sets nitrogen cylinder 7 and transmits nitrogen as 150CCM, opens nitrogen valve
13, transmission product18F-NaF is in product bottle 4.
Above procedure sets after parameter can be simple to operate, production efficiency is high, medicine concordance by computer full-automatic control
Good, safety and stability.
Claims (7)
1. one kind18F-NaF Fully automated synthesis device, it is characterised in that: include 18F target (1), QMA post (2), waste liquid bottle (3), produce
Product bottle (4), aseptic water bottle (5), normal saline bottle (6) and nitrogen cylinder (7), described 18F target (1) passes through QMA post (2) respectively with useless
Liquid bottle (3) and product bottle (4) couple, described aseptic water bottle (5), normal saline bottle (6) and nitrogen cylinder (7) respectively with QMA post (2)
Coupling, described QMA post (2) also couples radioactivity seeker (8).
One the most according to claim 118F-NaF Fully automated synthesis device, it is characterised in that: described 18F target (1) is passed through
V321 valve (9) couples with QMA post (2).
One the most according to claim 118F-NaF Fully automated synthesis device, it is characterised in that: described QMA post (2) is passed through
V317 valve (10) couples with waste liquid bottle (3), is coupled with product bottle (4) by V316A valve (11).
One the most according to claim 118F-NaF Fully automated synthesis device, it is characterised in that: described aseptic water bottle (5),
Normal saline bottle (6) and nitrogen cylinder (7) are all coupled with QMA post (2) by V320 valve (12).
One the most according to claim 418F-NaF Fully automated synthesis device, it is characterised in that: described nitrogen cylinder (7) with
Nitrogen valve (13) it is provided with between V320 valve (12).
One the most according to claim 418F-NaF Fully automated synthesis device, it is characterised in that: described aseptic water bottle (5)
And being provided with sterilized water syringe (14) between V320 valve (12), described sterilized water syringe (14) couples V318 valve
(15)。
One the most according to claim 418F-NaF Fully automated synthesis device, it is characterised in that: described normal saline bottle
(6) and being provided with physiological saline device (16) between V320 valve (12), described physiological saline device (16) couples to be had
V316B valve (17).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521126548.7U CN205709900U (en) | 2015-12-23 | 2015-12-23 | A kind of18f NaF Fully automated synthesis device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521126548.7U CN205709900U (en) | 2015-12-23 | 2015-12-23 | A kind of18f NaF Fully automated synthesis device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205709900U true CN205709900U (en) | 2016-11-23 |
Family
ID=57334530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201521126548.7U Expired - Fee Related CN205709900U (en) | 2015-12-23 | 2015-12-23 | A kind of18f NaF Fully automated synthesis device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205709900U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113955771A (en) * | 2021-10-29 | 2022-01-21 | 北京善为正子医药技术有限公司 | Automatic synthesis method for rapidly preparing 18F sodium fluoride PET (polyethylene terephthalate) medicine |
-
2015
- 2015-12-23 CN CN201521126548.7U patent/CN205709900U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113955771A (en) * | 2021-10-29 | 2022-01-21 | 北京善为正子医药技术有限公司 | Automatic synthesis method for rapidly preparing 18F sodium fluoride PET (polyethylene terephthalate) medicine |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20161123 Termination date: 20181223 |