CN205459326U - A equipment for inducing anti cervical human papilloma virus of immune infects - Google Patents

A equipment for inducing anti cervical human papilloma virus of immune infects Download PDF

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Publication number
CN205459326U
CN205459326U CN201620080552.2U CN201620080552U CN205459326U CN 205459326 U CN205459326 U CN 205459326U CN 201620080552 U CN201620080552 U CN 201620080552U CN 205459326 U CN205459326 U CN 205459326U
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heater block
equipment
input port
cervical
temperature controller
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CN201620080552.2U
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高兴华
齐瑞群
杨阳
陈洪铎
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First Hospital of China Medical University
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First Hospital of China Medical University
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Abstract

The utility model provides an equipment for inducing anti cervical human papilloma virus of immune infects belongs to medical equipment technical field, especially relates to an equipment for inducing anti cervical human papilloma virus of immune infects. The utility model provides a an equipment for inducing anti cervical human papilloma virus of immune infects who is showing to cervical carcinoma patient treatment. The utility model discloses a casing is provided with temperature controller in its structural feature casing, temperature controller's output port links to each other with control line one end, and the control line other end passes the spy income pole that can get into the cervical and the heater block that can get into the cervical links to each other, and the pole end fixing is gone into with the spy to the heater block, the heater block is discoid heater block, and the center and the spy of discoid heater block are gone into rod end portion and is linked to each other, are provided with temperature sensor in the discoid heater block, and temperature sensor's signal output part links to each other with feedback line one end, and the feedback line other end passes it is continuous with temperature controller's input port to visit the pole.

Description

A kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism
Technical field
This utility model belongs to technical field of medical equipment, particularly relates to a kind of equipment for inducing the anti-cervical human papillomavirus-affected of immunity of organism.
Background technology
Human papillomavirus (human papillomavirus, HPV) is a kind of double-strand closed hoop DNA viruses, closely related with the cancer of the mankind 5%.The pathology sample of nearly all cervical cancer patient all can find HPV virus.Cervical cancer and precancerous lesion Cervical intraepitheliaI neoplasia (CIN) thereof, infect relevant to lasting high-risk HPV mostly.After HPV infection cell, by mechanism such as the function effects to antioncogene, cause cell carcinogenesis.In the world, in women cervix uteri, the recall rate of HPV is about 11.7%, so every year will newly-increased substantial amounts of cervix uteri high-risk HPV carrier.Although the HPV infection of about 70% can spontaneous be removed in 1 year, but the annual new cervical cancer patient sent out remains above 400,000 people, and wherein 1/3rd occur in China.HPV vaccine succeed in developing and apply the incidence rate greatly reducing cervical cancer, but China carries out the most comprehensively;Even if carrying out comprehensive vaccination, it is contemplated that also will receive effect after 30-50.During this period, China will increase 400 to 800 ten thousand cervical cancer patients newly.Therefore, find the effective method removing cervix uteri high-risk HPV prevention cervical cancer is of great practical significance.
In order to remove HPV infection and prevent the precancerous lesions of uterine cervix conversion to invasive carcinoma, the most the more commonly used remedy measures has: radiotherapy, laser cone cut art, the physiotherapys such as surgery conization, leep knife, freezing, microwave, the method such as Drug therapy and therapeutic alliance such as a-interferon.
In Drug therapy, the application with interferon is the most universal, can interfere prime system system suppression after cervical infection HPV, and in peripheral blood cell, cumulative interference element reduces, and reduces with t lymphocyte subset group, and causes the change of cervix uteri local immunity environment.Interferon is applied topically to diseased region, the duplication of suppression virus.But the application cycle is long, uses loaded down with trivial details, and effect is limited, and has bigger side effect, such as fever, paralysis neuralis etc..
Leep knife is High frequency leep, after contact bodily tissue, impedance is produced by tissue itself, make hydrone moment concussion activation under high-frequency electric wave effect in destination organization, cell specimen is caused to rupture evaporation, and implement cut under low temperature state, stop blooding, fulgerize, melt the functions such as coagulation and cause albuminous degeneration and pathological tissues downright bad, simultaneously work as stopping blooding, promote tissue reconstruction, improve microcirculatory purpose.The method operation is fine, and few intercurrent disease is simple to operate, painful little, but range of operation more limits to, and pathological changes diameter is often less than 2.5cm, and the degree of depth is about 7mm;Although operation wound is little compared with than traditional approach, but also cervix uteri is caused and damage in various degree, postoperative need to recover 2~6 months, and have and necessarily recur probability.Therefore, Follow-up After, regular row cytolgical examination is extremely important.
Cold therapy: be chilled on treatment CIN I, II and can obtain relatively good therapeutic effect, but therapeutic effect is poor in CIN is III grade.Cold therapy is simple to operate, and the treatment degree of depth is up to 3~4mm, but a few patients needs repetitive therapy repeatedly, be especially expert at deep therapy time increase misery, and have and necessarily recur probability.
Laser cone cuts art: laser therapy is easy and simple to handle, treatment is accurate, organization healing is fast and few intercurrent disease.But still tissue can be caused damage in various degree, and the conscious pain of patient, hemorrhage more, post-operative recovery time is long.
Because of many, surgery conization: conization of cervix is the most conventional traditional therapy, reports that cones cut postoperative remaining focus and relapse rate is high, relatively big to disorganization, and complication is many, and many opinions are strict grasps the indication that cone is cut.
Summary of the invention
This utility model is aiming at the problems referred to above, it is provided that a kind of equipment being significantly used for for cervical cancer patient therapeutic effect inducing the anti-cervical human papillomavirus-affected of immunity of organism.
For achieving the above object, this utility model adopts the following technical scheme that, this utility model includes housing, it is provided with temperature controller in its structural feature housing, the output port of temperature controller is connected with control line one end, the control line other end is connected through the bar that probes into that can enter cervix uteri with the heater block that can enter cervix uteri, and heater block is fixed with probeing into boom end;Described heater block is discoid heater block, the center of discoid heater block is connected with probeing into boom end, it is provided with temperature sensor in discoid heater block, the signal output part of temperature sensor is connected with feedback line one end, the feedback line other end pass described in probe into bar and be connected with the input port of temperature controller.
As a kind of preferred version, discoid heater block described in the utility model is internal is ceramic heating flake.
As another kind of preferred version, temperature sensor described in the utility model is three, is distributed on along ceramic heating flake bottom surface along ceramic heating flake circumference.
As another kind of preferred version, the bar that probes into described in the utility model is the cylindric bar that probes into, the cylindric external diameter diameter less than described discoid heater block probeing into bar.
As another kind of preferred version, control line described in the utility model is connected by detachable plug with the connection end of temperature controller with feedback line.
As another kind of preferred version, temperature controller described in the utility model controls during the single heating of described heater block a length of 20~30 minutes.
As another kind of preferred version, it is 40~45 degrees Celsius that temperature controller described in the utility model controls the heating-up temperature of described heater block.
As another kind of preferred version, outside the control line probeed between bar and detachable plug described in the utility model and feedback line, it is cased with rubber hose.
nullSecondly,Temperature controller described in the utility model includes constant-current source module、D/A modular converter、A/D modular converter、Single-chip microcomputer、Current detection module、Turn off and control part and voltage detection module,The output port of power source of constant-current source module is the output port of described temperature controller,The control signal input port of constant-current source module is connected with the output port of D/A modular converter,The input port of D/A modular converter is connected with the control signal output port of single-chip microcomputer,The control signal output port of single-chip microcomputer is connected with turning off the input port controlling part,The output port turning off control part is connected with the shutoff control signal input port of constant-current source module,The current detecting port of constant-current source module is connected with the input port of A/D modular converter by current detection module,The voltage detecting port of constant-current source module is connected with the input port of A/D modular converter by voltage detection module,The signal output part of described temperature sensor is connected with the input port of A/D modular converter,The output port of A/D modular converter is connected with the detection signal input port of single-chip microcomputer.
It addition, single-chip microcomputer described in the utility model provides reference voltage base according to described current detection signal, voltage detection signal, the output for constant-current source module.
Constant-current source module comparison reference voltage benchmark and current detection signal are to produce regulation voltage control signal;Voltage conversion is carried out further according to regulation voltage control signal;Carry out Current amplifier after voltage conversion and produce the first current signal;First current signal carries out Current amplifier again and produces the second current signal, and the second current signal produces the 3rd current signal after current limliting, produces the 4th current signal output to described heater block after the 3rd filtered process of current signal.
This utility model beneficial effect.
The effect that this utility model is brought and other existing equipments have essential distinction.By this utility model heater block, cervix uteri inside is heated, it is possible to induction body sets up the active immunity for HPV virus so that human body can recognize body defending system originally and can not recognize, the harmful ingress factor even developed as one pleases.And make this defence capability not reacting from naturalness, faint reaction brings up to the strongest immunoreation.This utility model is different from leep knife, and health does not cause the tissue injury that instantaneous height is thermally-induced;Cut art and cold therapy also different from laser cone and bodily tissue is caused the injuries such as downright bad damage;Cutting art also different from surgical drill, big to disorganization, complication is many, leaves over permanent cicatrix.
On market, some claim that various infrared or other firing equipments with health role, typically by bondage, simply play promotion vasodilation, sanguimotor effect by hot effect.Cervix uteri inside, by entering probeing into bar and can entering the heater block of cervix uteri of cervix uteri, is heated by this utility model, and the clinical effectiveness for cervical cancer patient treatment is notable.
Accompanying drawing explanation
With detailed description of the invention, this utility model is described further below in conjunction with the accompanying drawings.This utility model protection domain is not only limited to the statement of herein below.
Fig. 1 is this utility model structural representation.
Fig. 2 is that this utility model probes into bar and heater block structural representation.
Fig. 3 is this utility model heater block internal structure schematic diagram.
Fig. 4 is this utility model temperature controller schematic block circuit diagram.
In figure, 1 for detachable plug, 2 for housing, 3 for rubber hose, 4 for probe into bar, 5 for heater block, 6 for control line, 7 for ceramic heating flake, 8 for temperature sensor, 9 be feedback line.
Detailed description of the invention
As shown in the figure, this utility model includes housing 2, it is provided with temperature controller in housing 2, the output port of temperature controller is connected with control line 6 one end, control line 6 other end is through entering probeing into bar 4 and being connected with the heater block 5 that can enter cervix uteri of cervix uteri, and heater block 5 is fixed with probeing into bar 4 end;Described heater block 5 is discoid heater block 5, the center of discoid heater block 5 is connected with probeing into bar 4 end, it is provided with temperature sensor 8 in discoid heater block 5, the signal output part of temperature sensor 8 is connected with feedback line 9 one end, feedback line 9 other end pass described in probe into bar 4 and be connected with the input port of temperature controller.
Described discoid heater block 5 is internal is ceramic heating flake 7.
Described temperature sensor 8 is three, is distributed on along ceramic heating flake 7 bottom surface along ceramic heating flake 7 circumference;Thermometric is more accurate.
The described bar 4 that probes into is for the cylindric bar 4 that probes into, and the cylindric external diameter probeing into bar 4 is less than the diameter of described discoid heater block 5;Possesses suitable heating surface (area) (HS.
Described control line 6 is connected by detachable plug 1 with the connection end of temperature controller with feedback line 9;It is easy to probe into the dismounting of bar 4.
Described temperature controller control described heater block 5 single heating time a length of 20~30 minutes.According to clinical verification, optimum therapeuticing effect is reached.
It is 40~45 degrees Celsius that described temperature controller controls the heating-up temperature of described heater block.According to clinical verification, optimum therapeuticing effect is reached.
It is cased with rubber hose 3 outside the described control line 6 probeed between bar 4 and detachable plug 1 and feedback line 9;Control line 6 and feedback line 9 are effectively protected.
nullDescribed temperature controller includes constant-current source module、D/A modular converter、A/D modular converter、Single-chip microcomputer、Current detection module、Turn off and control part and voltage detection module,The output port of power source of constant-current source module is the output port of described temperature controller,The control signal input port of constant-current source module is connected with the output port of D/A modular converter,The input port of D/A modular converter is connected with the control signal output port of single-chip microcomputer,The control signal output port of single-chip microcomputer is connected with turning off the input port controlling part,The output port turning off control part is connected with the shutoff control signal input port of constant-current source module,The current detecting port of constant-current source module is connected with the input port of A/D modular converter by current detection module,The voltage detecting port of constant-current source module is connected with the input port of A/D modular converter by voltage detection module,The signal output part of described temperature sensor 8 is connected with the input port of A/D modular converter,The output port of A/D modular converter is connected with the detection signal input port of single-chip microcomputer.Single-chip microcomputer controls the output of constant-current source module according to detection electric current, detection voltage, heater block 5 can be in constant-current source pattern, it is ensured that the accurate control of temperature.It addition, electric current and voltage are detected in real time, it is possible to achieve the breakage detection function of heater block 5.Additionally, turn off control part can turn off constant-current source module in time.
Described single-chip microcomputer provides reference voltage base according to described current detection signal, voltage detection signal, the output for constant-current source module.
Constant-current source module comparison reference voltage benchmark and current detection signal are to produce regulation voltage control signal;Voltage conversion is carried out further according to regulation voltage control signal;Carry out Current amplifier after voltage conversion and produce the first current signal;First current signal carries out Current amplifier again and produces the second current signal, and the second current signal produces the 3rd current signal after current limliting, produces the 4th current signal output to described heater block 5 after the 3rd filtered process of current signal.
Embodiment: application this utility model treatment patient clinically, detection cervix uteri high-risk HPV infects the medical history in more than ten years, once used several Therapeutic Method, and be obviously improved as the treatment such as interferon, infrared, freezing, leep knife all loses, infect sustainable existence, and cervical scraping smear display cervix cells arrangement disorder, rear employing this utility model is treated 5 times, every day 1 time for three days on end, after one week, treatment 2 days the most continuously, every time treatment duration 20-30 minute.After 3 months, the detection of row cervical scraping smear finds that virus is eliminated, and cellular morphology recovers normal, achieves positive effect.Again checking after half a year, HPV detects feminine gender.
6 example patients are treated by application this utility model, and this 6 example patient is the case using existing additive method repeatedly to treat the most unsuccessful removing HPV infection state, and wherein 1 example is lost to follow-up, and remaining 5 example is the most successfully removed.
It is understandable that, above with respect to specific descriptions of the present utility model, it is merely to illustrate this utility model and is not limited to the technical scheme described by this utility model embodiment, it will be understood by those within the art that, still this utility model can be modified or equivalent, to reach identical technique effect;Needs are used, all within protection domain of the present utility model as long as meeting.

Claims (7)

1. the equipment being used for inducing the anti-cervical human papillomavirus-affected of immunity of organism, including housing, it is provided with temperature controller in its structural feature housing, the output port of temperature controller is connected with control line one end, the control line other end is connected through the bar that probes into that can enter cervix uteri with the heater block that can enter cervix uteri, and heater block is fixed with probeing into boom end;Described heater block is discoid heater block, the center of discoid heater block is connected with probeing into boom end, it is provided with temperature sensor in discoid heater block, the signal output part of temperature sensor is connected with feedback line one end, the feedback line other end pass described in probe into bar and be connected with the input port of temperature controller.
A kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism, it is characterised in that described discoid heater block is internal is ceramic heating flake.
A kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism, it is characterised in that described temperature sensor is three, is distributed on along ceramic heating flake bottom surface along ceramic heating flake circumference.
A kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism, it is characterised in that described in probe into bar be the cylindric bar that probes into, the cylindric external diameter diameter less than described discoid heater block probeing into bar.
A kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism, it is characterised in that described control line is connected by detachable plug with the connection end of temperature controller with feedback line.
A kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism, it is characterised in that described in probe into and be cased with rubber hose outside the control line between bar and detachable plug and feedback line.
nullA kind of for inducing the equipment of the anti-cervical human papillomavirus-affected of immunity of organism,It is characterized in that described temperature controller includes constant-current source module、D/A modular converter、A/D modular converter、Single-chip microcomputer、Current detection module、Turn off and control part and voltage detection module,The output port of power source of constant-current source module is the output port of described temperature controller,The control signal input port of constant-current source module is connected with the output port of D/A modular converter,The input port of D/A modular converter is connected with the control signal output port of single-chip microcomputer,The control signal output port of single-chip microcomputer is connected with turning off the input port controlling part,The output port turning off control part is connected with the shutoff control signal input port of constant-current source module,The current detecting port of constant-current source module is connected with the input port of A/D modular converter by current detection module,The voltage detecting port of constant-current source module is connected with the input port of A/D modular converter by voltage detection module,The signal output part of described temperature sensor is connected with the input port of A/D modular converter,The output port of A/D modular converter is connected with the detection signal input port of single-chip microcomputer.
CN201620080552.2U 2016-01-28 2016-01-28 A equipment for inducing anti cervical human papilloma virus of immune infects Active CN205459326U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105496637A (en) * 2016-01-28 2016-04-20 中国医科大学附属第一医院 Equipment for inducing body immunity to resist cervical human papilloma viral infection

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105496637A (en) * 2016-01-28 2016-04-20 中国医科大学附属第一医院 Equipment for inducing body immunity to resist cervical human papilloma viral infection
CN105496637B (en) * 2016-01-28 2018-07-13 中国医科大学附属第一医院 A kind of equipment for inducing the anti-cervical human papillomavirus-affected of immunity of organism

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