CN205458704U - Blood sugar concentration detection device of affine type - Google Patents

Blood sugar concentration detection device of affine type Download PDF

Info

Publication number
CN205458704U
CN205458704U CN201620064599.XU CN201620064599U CN205458704U CN 205458704 U CN205458704 U CN 205458704U CN 201620064599 U CN201620064599 U CN 201620064599U CN 205458704 U CN205458704 U CN 205458704U
Authority
CN
China
Prior art keywords
semipermeable membrane
blood sugar
field effect
mos structure
sugar concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201620064599.XU
Other languages
Chinese (zh)
Inventor
马铁英
李达波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
China Jiliang University
Original Assignee
China Jiliang University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by China Jiliang University filed Critical China Jiliang University
Priority to CN201620064599.XU priority Critical patent/CN205458704U/en
Application granted granted Critical
Publication of CN205458704U publication Critical patent/CN205458704U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The utility model provides a blood sugar concentration detection device of affine type, includes difference formula MOS structure, and outside encapsulating material and external data gather and processing system, and for making the close sugared polymer field effect capacitor layer of can not flowing, the use of surface aperture be 5nm's graphite alkene and still regards as the field effect capacitor layer some as pellicle, pellicle, is vibrated by the pulse to force its vibration, to detecting stability, accuracy problem, adopt the compensation of difference formula MOS structure, to the data acquisition problem, the metal level is " returning " font form makes outside antenna carry out data acquisition to the device, its external data gathers and processing system can and gather because the blood sugar concentration changes the drain -source current data who arouses the change of pellicle amplitude and produce for difference formula MOS structure wireless power supply, and handle according to the drain -source current data who gathers and finally obtain the blood sugar concentration data, this detection device need not to implant in vivo power supply unit, realize that internal blood sugar concentration detects in succession, stability, the fault simulation test device is high in accuracy, the comprehensive compensation device is rapid in response speed.

Description

A kind of blood sugar concentration detection device of affinity type
Technical field
This utility model relates to a kind of blood sugar concentration detection device, particularly relates to the blood sugar concentration of a kind of affinity type Detection device.
Background technology
Diabetes affect the patient of China nearly 100,000,000, and diabetes are by internal insulin definitely or the most scarce The weary the concentration of glucose in blood that causes raises caused, and then substantial amounts of sugar is discharged from urine, human body then in Reveal polydipsia, polyuria, polyphagia, become thin, the symptom such as dizzy, weak, its complication be cause blind, last The main cause of phase nephropathy etc., the way that diabetes are not the most effected a radical cure.Diabetes have become the world today Threaten one of serious disease of human health, but blood sugar detection apparatus remains a need for being significantly improved.Closely Monitoring and regulation blood sugar concentration can significantly (more than 50%) reduce diabetic complication incidence rate.To glucose Concentration carries out the continuous glucose monitoring (CGM) that altofrequency is uninterruptedly measured, be monitoring blood sugar concentration Effective way.
The patent of invention " a kind of transmission-type noninvasive dynamics monitoring device " of Application No. CN201410205838.4, Proposing the detection device and method of a kind of transmission-type Woundless blood sugar, this invention uses light transmission finger, utilizes light Photodetector detection optical signalling is simultaneously converted into the signal of telecommunication, so the signal of telecommunication is amplified, demodulate, analyze and Being calculated blood sugar concentration, advantage is its noinvasive, disadvantage thereof however is that: can not from external collection data Real contact blood itself, error is relatively big, measures the cycle longer.
The patent of invention " a kind of blood sugar detection apparatus and preparation method thereof " of Application No. CN201310751879.9, Propose a kind of blood sugar detection apparatus based on colour developing reagent paper, judge blood by the colour developing situation of detection colour developing reagent paper The concentration of sugar, advantage is: employing face takes the way of blood, takes blood wound less, and accuracy of measurement is higher, Shortcoming is: detection human blood glucose concentration will be taken a blood sample every time, cumbersome, and the cycle of measurement is longer.
Summary of the invention
In order to overcome the shortcoming of above-mentioned blood sugar test, solve the problems such as detection cycle length, the purpose of this utility model It is to provide the blood sugar concentration detection device of a kind of affinity type, can embed in human body, it is not necessary to blood sampling, and this dress Permission blood glucose molecule turnover is not only in the effect putting semipermeable membrane, also as a part for field effect capacitor layer, by Pulsatile motion forces it to vibrate, it is not necessary to the external world is additionally provided power.This device can realize continuous glucose prison Survey, and stability, accuracy are high, fast response time.
The technical scheme that this utility model solution problem is used is: the blood sugar concentration detection dress of a kind of affinity type Putting, its device includes: differential type MOS structure, outer enclosure material and external data collection and processing system, It is characterized in that differential type MOS structure includes left side MOS structure, the right MOS structure, be mounted with parent The left side field effect capacitor layer of glycopolymers, the right field effect capacitor layer, left side semipermeable membrane, the right semipermeable membrane, One block of hydrogel, its left side MOS structure and the right MOS structure include a block length cube silicon from bottom to top Substrate, is positioned at the left side back grid at silicon substrate diagonal angle 1/4th and at 3/4ths and the right back grid, The oxide layer of the covering whole substrate in addition to left side field effect capacitor layer and the right field effect capacitor layer and covering The metal level in " returning " word shape of whole oxide layer, it is mounted with the left side field effect electricity of parent's glycopolymers Hold layer and the right field effect capacitor layer by the silicon substrate of lower section, middle oxide layer and the left side semipermeable membrane of top, The right semipermeable membrane composition, its left side semipermeable membrane and the right semipermeable membrane lay respectively at left side field effect capacitor layer and the right side The surface of limit field effect capacitor layer and be positioned at below metal level, its hydrogel is positioned at directly over the semipermeable membrane of the right, The lower section of metal level, size is equal with the right semipermeable membrane, its outer enclosure material cover except left side back grid and The whole apparatus surface in the vertical up space of the right back grid, its external data collection and processing system are right against Differential type MOS structure, including exterior antenna and wireless power supply.
In described blood sugar detection apparatus, left side semipermeable membrane and the right semipermeable membrane are Graphene, and pore size is 5nm。
In described blood sugar detection apparatus, parent's glycopolymers is poly-3-acrylamide phenylboric acid-acrylamide.
Described blood sugar monitor peripheral encapsulating material is affinity type material SU-8.
Owing to using such scheme, the invention have the advantages that
(1) Graphene had not both allowed parent's glycopolymers to enter as allowing blood glucose molecule to enter field effect capacitor layer Enter the semipermeable membrane in blood, again as the part composition of field effect capacitor layer, utilize beat pulse to force it Vibration, without power is provided separately, optimizes self structure.
(2) utilize differential type MOS structure to eliminate the non-coefficient of viscosity and change the impact brought, suppression detection signal Drift.
(3) realize the continuous detecting of blood glucose, and stability, accuracy are high, fast response time.
Accompanying drawing explanation
The present invention is described further with specific embodiment below in conjunction with the accompanying drawings.
Fig. 1 is the structural profile schematic diagram of this blood sugar detection apparatus.
Fig. 2 is the differential type MOS structure generalized section of this blood sugar detection apparatus.
Fig. 3 is substrate and the back grid side view of this blood sugar detection apparatus.
Fig. 4 is oxide layer and the semipermeable membrane side view of this blood sugar detection apparatus.
Fig. 5 is differential type MOS structure and the outer enclosure material side view of this blood sugar detection apparatus.
Detailed description of the invention
In Fig. 1 to Fig. 5, the blood sugar concentration detection device of a kind of affinity type, its device includes: differential type MOS Structure 10, outer enclosure material 20 and external data collection and processing system 30, it is characterised in that differential type MOS structure includes left side MOS structure 101, the right MOS structure 102, is mounted with parent's glycopolymers Left side field effect capacitor layer 103, the right field effect capacitor layer 104, left side semipermeable membrane 105, the right semipermeable membrane 106, one block of hydrogel 107, its left side MOS structure 101 and the right MOS structure 102 include from bottom to top A block length cube silicon substrate 1011, be positioned at silicon substrate diagonal angle 1/4th and at 3/4ths the left side back of the body Grid 1012 and the right back grid 1021, cover except left side field effect capacitor layer 103 and the right field effect capacitor The oxide layer 1013 of the whole silicon substrate 1011 beyond layer 104 and cover whole oxide layer 1013 in " returning " The metal level 1014 of word shape, its left side field effect capacitor layer 103 being mounted with parent's glycopolymers and field, the right Effect capacitor layers 104 is by the silicon substrate 1011 of lower section, middle oxide layer 1013 and the left side semipermeable membrane of top 105, the right semipermeable membrane 106 forms, and its left side semipermeable membrane 105 and the right semipermeable membrane 106 lay respectively at the left side Field effect capacitor layer 103 and the surface of the right field effect capacitor layer 104 and be positioned at below metal level 1014, Its hydrogel 107 is positioned at directly over the semipermeable membrane 106 of the right, the lower section of metal level 1014, size and the right half Permeable membrane 106 is equal, and its outer enclosure material 20 covers except left side back grid 1012 and the right back grid 1021 The whole apparatus surface in vertical up space, its external data collection and processing system 30 are right against differential type MOS structure 10, including exterior antenna and wireless power supply.

Claims (4)

1. a blood sugar concentration detection device for affinity type, its device includes: differential type MOS structure, outward Portion's encapsulating material and external data collection and processing system, it is characterised in that differential type MOS structure includes the left side MOS structure, the right MOS structure, be mounted with the parent left side field effect capacitor layer of glycopolymers, field, the right Effect capacitor layers, left side semipermeable membrane, the right semipermeable membrane, one block of hydrogel, its left side MOS structure and the right MOS structure includes a block length cube silicon substrate from bottom to top, is positioned at silicon substrate diagonal angle 1/4th and four Left side back grid at/tri-and the right back grid, cover except left side field effect capacitor layer and the right field effect The oxide layer of the whole substrate beyond capacitor layers and the metal level in " returning " word shape of the whole oxide layer of covering, Its left side field effect capacitor layer being mounted with parent's glycopolymers and the right field effect capacitor layer are served as a contrast by the silicon of lower section The end, middle oxide layer and the left side semipermeable membrane of top, the right semipermeable membrane forms, its left side semipermeable membrane and right side Limit semipermeable membrane lays respectively at left side field effect capacitor layer and the surface of the right field effect capacitor layer and is positioned at metal Below Ceng, its hydrogel is positioned at directly over the semipermeable membrane of the right, the lower section of metal level, size and the right semipermeable membrane Equal, its outer enclosure material covers the whole dress except left side back grid up space vertical with the right back grid Putting surface, its external data collection and processing system are right against differential type MOS structure, including exterior antenna and Wireless power supply.
The blood sugar concentration detection device of a kind of affinity type the most according to claim 1, it is characterised in that left Limit semipermeable membrane and the right semipermeable membrane material are Graphene, and surface aperture size is 5nm.
The blood sugar concentration detection device of a kind of affinity type the most according to claim 1, it is characterised in that parent Glycopolymers is poly-3-acrylamide phenylboric acid-acrylamide.
The blood sugar concentration detection device of a kind of affinity type the most according to claim 1, it is characterised in that outer Portion's encapsulating material is affinity type material SU-8.
CN201620064599.XU 2016-01-19 2016-01-19 Blood sugar concentration detection device of affine type Expired - Fee Related CN205458704U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620064599.XU CN205458704U (en) 2016-01-19 2016-01-19 Blood sugar concentration detection device of affine type

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620064599.XU CN205458704U (en) 2016-01-19 2016-01-19 Blood sugar concentration detection device of affine type

Publications (1)

Publication Number Publication Date
CN205458704U true CN205458704U (en) 2016-08-17

Family

ID=56638284

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201620064599.XU Expired - Fee Related CN205458704U (en) 2016-01-19 2016-01-19 Blood sugar concentration detection device of affine type

Country Status (1)

Country Link
CN (1) CN205458704U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106974661A (en) * 2016-01-19 2017-07-25 中国计量学院 A kind of blood sugar concentration detection means of affinity type

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106974661A (en) * 2016-01-19 2017-07-25 中国计量学院 A kind of blood sugar concentration detection means of affinity type

Similar Documents

Publication Publication Date Title
Chung et al. Wearable flexible sweat sensors for healthcare monitoring: a review
Lin et al. Wearable biosensors for body computing
Moyer et al. Correlation between sweat glucose and blood glucose in subjects with diabetes
Ji et al. Wearable sweat biosensors refresh personalized health/medical diagnostics
Heng et al. Emerging wearable flexible sensors for sweat analysis
Das et al. Electrochemical nanosensors for sensitization of sweat metabolites: from concept mapping to personalized health monitoring
CN202020429U (en) Intraoperative hemorrhage amount detector
CN205433706U (en) Noninvasive glucose monitoring based on finger detects
Su et al. A wearable sensing system based on smartphone and diaper to detect urine in-situ for patients with urinary incontinence
CN204121004U (en) A kind of pulse diagnostic information acquisition device in conjunction with multiple pressure-type sensor
CN106535763A (en) Device and mechanism for facilitating non-invasive, non-piercing monitoring of blood glucose
CN104667368B (en) Control with calculating the insulin pump dynamic control implementation method separated
Faham et al. Electrochemical-based remote biomarker monitoring: Toward Internet of Wearable Things in telemedicine
CN205458704U (en) Blood sugar concentration detection device of affine type
CN202330343U (en) Acetone gas sensor detection device
Valenti et al. Wearable multisensor ring-shaped probe for assessing stress and blood oxygenation: Design and preliminary measurements
Wu et al. Stable and Dynamic Multiparameter Monitoring on Chests Using Flexible Skin Patches with Self‐Adhesive Electrodes and a Synchronous Correlation Peak Extraction Algorithm
CN208511033U (en) A kind of double blood oxygen Congenital Heart Disease of Newborns detectors
Xing et al. Recent Advances in Wearable Sensors for the Monitoring of Sweat: A Comprehensive Tendency Summary
Dkhar et al. Engineering design, implementation, and sensing mechanisms of wearable bioelectronic sensors in clinical settings
CN203299204U (en) Portable glucometer
CN205234512U (en) Wearable high accuracy blood sugar check out test set
CN103402427A (en) Torso dimension-measuring device and body fat-measuring device
CN107951492A (en) A kind of noninvasive dynamics monitoring device
CN101968450A (en) Embedded porphyrin sensor array-based saliva sugar and urine sugar detector

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160817

Termination date: 20170119