CN205388592U - Liquid accuse temperature high performance liquid chromatography column incubator - Google Patents

Liquid accuse temperature high performance liquid chromatography column incubator Download PDF

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Publication number
CN205388592U
CN205388592U CN201620070250.7U CN201620070250U CN205388592U CN 205388592 U CN205388592 U CN 205388592U CN 201620070250 U CN201620070250 U CN 201620070250U CN 205388592 U CN205388592 U CN 205388592U
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China
Prior art keywords
liquid
chromatographic column
temperature
circulator
temperature control
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Application number
CN201620070250.7U
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Chinese (zh)
Inventor
郭光明
李志刚
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BEIJING BOENTE PHARMACEUTICAL Co Ltd
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BEIJING BOENTE PHARMACEUTICAL Co Ltd
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Priority to CN201620070250.7U priority Critical patent/CN205388592U/en
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Abstract

The utility model discloses a liquid accuse temperature high performance liquid chromatography column incubator of having higher hot conduction efficiency. With adding required liquid in the cold and hot circulator, link circulator and chromatographic column accuse temperature groove, liquid pipe entry and the export of liquid pipe, put into the liquid chromatogram post, build the upper cover after liquid chromatogram post both ends buckle is good, open cold and hot circulator, set up the temperature, after fluid passage liquid pipe entry gets into chromatographic column accuse temperature groove, transfer the liquid chromatogram post with the temperature, then circulate in the circulator from liquid pipe export outflow, can use after treating the constancy of temperature.

Description

Liquid temperature control performance liquid chromatographic column incubator
Technical field
This utility model belongs to instrument and equipment field, relates to a kind of liquid temperature control performance liquid chromatographic column incubator.
Background technology
High performance liquid chromatography (HighPerformanceLiquidChromatography HPLC) is also known as " high pressure liquid chromatography ", " high-speed liquid chromatography ", " high separation liquid chromatograph ", " column chromatography in modern age " etc..High performance liquid chromatography is a chromatographic important branch, with liquid for mobile phase, adopt high pressure transfusion system, the mobile phases such as the mixed solvent of single solvent or different proportion with opposed polarity, buffer are pumped into the chromatographic column equipped with fixing phase, in post each composition separated after, enter detector to detect, thus realizing the analysis to sample.
The system of performance liquid chromatographic column is made up of several parts such as reservoir, pump, injector, chromatographic column, detector, monitors.Mobile phase in reservoir is squeezed into system by high-pressure pump, sample solution enters mobile phase through injector, it is loaded in chromatographic column (fixing phase) by mobile phase, owing to each component in sample solution has different partition coefficients in biphase, when making relative motion in biphase, assigning process through repeated multiple times absorption-desorption, each component produces bigger difference in translational speed, it is separated into single component to flow out in post successively, during by detector, sample concentration is converted into the signal of telecommunication and is sent to monitor, and data print with collection of illustrative plates form.
The temperature of performance liquid chromatographic column is relatively big to the process influence of different material absorption and desorbing, and when chromatographic column is heated by tradition chromatograph column oven, gap is relatively big, and conduction efficiency is relatively low.
Summary of the invention
This utility model is in that to provide a kind of liquid temperature control performance liquid chromatographic column incubator with higher thermal conduction efficiency.This incubator has liquid-phase chromatographic column 1, column temperature tank wall 2, chromatographic column temperature control tank 3, liquid line entrance 4 and liquid line outlet 5;Liquid-phase chromatographic column 1 two ends movable buckle is in chromatographic column temperature control tank 3;Liquid line entrance 4 and liquid line export 5 and lay respectively at the parallel relative position of chromatographic column temperature control tank 3.
Liquid temperature control performance liquid chromatographic column incubator includes cold-hot circulating machine and liquid-phase chromatographic column temperature control tank.In cold-hot circulating machine, liquid includes ethanol, water, silicone oil, different temperature requirements can be provided for chromatographic column, minimum can drop to-80 DEG C, the highest high temperature that can rise to 200 DEG C, provide bigger spatial choice for chromatographic column, select the cold-hot circulating machine of large volume to control more stable to temperature.Chromatographic column temperature control tank 3 is to be placed in groove by liquid-phase chromatographic column 1 and blocked at liquid-phase chromatographic column 1 two ends to be fixed in groove, liquid line entrance 4 enter liquid, and liquid line exports 5 output liquids, and liquid by chromatographic column submergence, can have upper cover to prevent liquid leakage.
Accompanying drawing explanation
Fig. 1 is liquid temperature control performance liquid chromatographic column incubator sectional view, and 1 is liquid-phase chromatographic column, and 2 is column temperature tank wall, and 3 is chromatographic column temperature control tank, and 4 is liquid line entrance, and 5 export for liquid line.
Detailed description of the invention
Required liquid will be added in cold-hot circulating machine, link circulator and chromatographic column temperature control tank 3, liquid line entrance 4 and liquid line outlet 5, put into liquid-phase chromatographic column 1, the good upper cover of bonnet buckled well by liquid-phase chromatographic column 1 two ends card, opens cold-hot circulating machine, sets temperature, after liquid enters chromatographic column temperature control tank 3 by liquid line entrance 4, temperature is passed to liquid-phase chromatographic column 1, then exports 5 outflows from liquid line and circulate to circulator, can use after temperature constant.

Claims (1)

1. a liquid temperature control performance liquid chromatographic column incubator, it is characterized in that this incubator has liquid-phase chromatographic column (1), column temperature tank wall (2), chromatographic column temperature control tank (3), liquid line entrance (4) and liquid line outlet (5);Liquid-phase chromatographic column (1) two ends movable buckle is in chromatographic column temperature control tank (3);Liquid line entrance (4) and liquid line export (5) and lay respectively at the parallel relative position of chromatographic column temperature control tank (3).
CN201620070250.7U 2016-01-25 2016-01-25 Liquid accuse temperature high performance liquid chromatography column incubator Active CN205388592U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620070250.7U CN205388592U (en) 2016-01-25 2016-01-25 Liquid accuse temperature high performance liquid chromatography column incubator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620070250.7U CN205388592U (en) 2016-01-25 2016-01-25 Liquid accuse temperature high performance liquid chromatography column incubator

Publications (1)

Publication Number Publication Date
CN205388592U true CN205388592U (en) 2016-07-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201620070250.7U Active CN205388592U (en) 2016-01-25 2016-01-25 Liquid accuse temperature high performance liquid chromatography column incubator

Country Status (1)

Country Link
CN (1) CN205388592U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108226364A (en) * 2016-12-09 2018-06-29 中国科学院大连化学物理研究所 The constant temperature system and operating method of a kind of liquid chromatogram

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108226364A (en) * 2016-12-09 2018-06-29 中国科学院大连化学物理研究所 The constant temperature system and operating method of a kind of liquid chromatogram
CN108226364B (en) * 2016-12-09 2020-08-11 中国科学院大连化学物理研究所 Constant temperature system of liquid chromatogram

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