CN205280649U - Excision thing real -time detection system - Google Patents
Excision thing real -time detection system Download PDFInfo
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- CN205280649U CN205280649U CN201520942827.4U CN201520942827U CN205280649U CN 205280649 U CN205280649 U CN 205280649U CN 201520942827 U CN201520942827 U CN 201520942827U CN 205280649 U CN205280649 U CN 205280649U
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- scalpel
- pipe
- detecting system
- excision thing
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Abstract
The utility model discloses an excision thing real -time detection system, including scalpel, sampling device, ion mobility spectrometer with be used for showing the display screen of ion mobility spectrometer testing result, the sampling device includes the second pipeline that is equipped with the first pipeline of a plurality of exhaust fan in the lumen and connects first pipeline inlet end and scalpel, the air inlet face to the exhaust fan is rectified in admitting air of first pipeline, and the introduction port of the give vent to anger end and the ion mobility spectrometer of first pipeline feeds through, the inlet end of second pipeline is started from to the work distal process of scalpel, and the inner wall at second pipeline inlet end is fixed to the bottom of scalpel, the ionization chamber of ion mobility spectrometer in be equipped with the filter screen of taking the ionization source. This detecting system, simple structure, the easy manufacturing, convenient to use can carry out real -time measuring to the excision thing at the in -process that the operation is gone on, the sample integrity is good, the testing result is accurate, quick, greatly reduced the error operation the during excision.
Description
Technical field
The utility model relates to medical instruments field, is specifically related to a kind of excision thing real-time detecting system.
Background technology
Operation generally refers to the treatments such as excision that patient body carries out by doctor with medicine equipment, stitching. With cutter, cut, operation that the apparatus such as pin carries out at body local, maintain the health of patient, be the primary treatments of surgery, be commonly called as " operating on "; Object cures or diagnosis disease, as removed pathological tissues, repair damage, transplant organ, the function and morphology etc. that improves body.
At present, the detection of excision thing is general adopts conventional histopathology method to make pathological section, checks pathology further with electron microscope. Along with the development of detection technique, some new inspection methods and detection device are engendered, such as: immunohistochemical detection, its principle is the unknown antigen or antibody that utilize the specific binding reaction of antigen and antibody to detect in tissue, has occurred the detection kit for various material accordingly. The existing detection device for detecting excision thing is all excision thing carries out detection after operation terminates analyze, such as it is mainly used in clearly diagnosing and verifying the pathologic finding of preoperative diagnosis, detected result often has the hysteresis quality of long period, can not the carrying out of guided operation in time.
The main process of operation is by scalpel incision, chorista and excision pathology. Conventional scalpel is stainless steel scalpel, growing along with science and technology, in order to reach cutting fast, accurately, cut time there is hemostasis, without objects such as infection, people investigated the multiple novel scalpels such as electric knife, micro-wave scalpel, ultrasonic surgical blade, laser scalpel. Wherein the surgical device such as electric knife, ultrasonic surgical blade, laser scalpel can produce operation smoke in use, operation smoke refers to the smoke-like material produced in surgical procedure, it is also referred to as aerosol, burn cigarette, diathermanous plumes etc., by electric knife, laser scalpel, ultrasonic surgical blade, high speed bit, saw blade, apparatus burr destruction, vaporization excision thing tissue protein and lipogenesis in surgical procedures. Operation smoke is generally made up of water or water vapor and the cell debris that exists with particle form, mostly is hazardous and noxious substances, generally it can be filtered or discharge after purifying treatment again. If the excision thing in surgical procedure can carry out detection timely analyze the carrying out being expected to guided operation in time, improve the accuracy rate performed the operation. The detection system also not detected in time for the excision thing in surgical procedure in prior art.
As shown in Figure 1, existing ion mobility spectrometry (IMS) instrument 10 comprises the injection port 1, the vaporizer 2 for the sample that gasifies of band high temperature heat source, the ionization chamber 3 of band ionizer, migration tube 4, detector 5, amplifier 6, A/D sampling thief 7, data processing unit 8 and the database 9 that connect successively. The main application fields of current IMS instrument 10 concentrates on the detection of explosive substance and drugs, yet there are no application in excision analyte detection system.
Practical novel content
The purpose of this utility model is to overcome the deficiencies in the prior art, provide a kind of excision thing real-time detecting system, in time excision thing can be detected in the process that operation carries out, sample integrity is good, detected result is accurate, quick, error operation when greatly reducing excision.
A kind of excision thing real-time detecting system, comprises scalpel, sampling apparatus, ionic migration spectrometer and the display screen for showing ionic migration spectrometer detected result;
Described sampling apparatus is used for collected specimens and sample is sent to the injection port of ionic migration spectrometer, and sampling apparatus comprises the first pipeline being provided with some exhaust fans in pipe chamber and connects the second pipe of the first pipeline air-inlet end and scalpel; The air intake surface to exhaust fan is rectified in the air inlet of described first pipeline, and the outlet side of the first pipeline is connected with the injection port of ionic migration spectrometer;
The working end of described scalpel protrudes from the air inlet end of second pipe, and the bottom of scalpel is fixed on the inwall of second pipe air inlet end;
The ionization chamber of described ionic migration spectrometer is provided with the filtering net of band ionizer.
Described sample comprise formed by excision thing operation smoke, one or both in scalpel surrounding environment material.
After sample enters from the injection port of ionic migration spectrometer; can successively through the ionization of vaporizer gasification and ionization chamber; ionization chamber arranges the filtering net of band ionizer; can effectively be arrested on the filtering net of band ionizer by a small amount of liquid that may not gasify completely in sample and solid to ionize further; can either better ensure the integrity of sample; ionic migration spectrometer can be protected again, extend its work-ing life. As preferably, the described ionizer on filtering net selects existing ionizer, can adopt the one in electron impact ionization source (EI), chemical ionization source (CI), fast atom bombardment source (FAB), field desorption(FD) source (FD), electric spray ion source (ESI), atmosphere pressure chemical ion source (APCI) or two or more combination.
As preferably, described first inner-walls of duct, second pipe inwall and exhaust fan outside surface are equipped with non-sticky metallic coating, non-sticky metallic coating preferably super-hydrophobic further, it is possible to effectively avoid sample carryover inner at sampling apparatus, it is to increase the accuracy of detected result. Described non-sticky metallic coating can adopt existing non-sticky metallic coating, such as polytetrafluorethylecoatings coatings, ceramic coating etc.
In order to more effective help sampling apparatus collected specimens, it is preferable that: described exhaust fan is positioned at the position of the first pipeline total length 1/1st to five/3rd and the outlet side of close described second pipe. The length of described second pipe is preferably 1 times to 1.5 times of scalpel length.
The duct section being provided with exhaust fan in described first pipeline is mechanically resistant material pipeline, is convenient to the installation and use of exhaust fan, and remaining pipes section can adopt soft material pipeline, easy to use. Described second pipe is mechanically resistant material pipeline, and the use handle that can serve as scalpel is convenient to the use of scalpel.
As preferably, the connection of the connection of described first pipeline air-inlet end and second pipe outlet side, the first pipeline outlet side and ionic migration spectrometer injection port all adopts detachable connection, the internal thread cooperatively interacted as adopted and outside screw connection etc., clean after for convenience detach.
As preferably, the air inlet end of described second pipe is horn-like, it is possible to expand the region of sampling.
As preferably, the bottom of described scalpel and the fixing mode of second pipe inwall are detachable, such as card groove, it is convenient to dismounting scalpel, convenient cleaning scalpel and second pipe.
As preferably, the bottom of described scalpel is fixed on the support being located at second pipe inwall, and the cutter hub of scalpel is along the central shaft axial distribution of second pipe, the inlet mouth of annular or class annular is formed between scalpel working end and second pipe air inlet end sidewall, scalpel working end pressed close to by inlet mouth, play the function of multi-angle, multi-faceted air-breathing, facilitate the use of medical personnel and sample can be sucked rapidly. The rack outer surface of described second pipe inwall scribbles non-sticky metallic coating.
Described scalpel comprises the surgical knife that electric knife, ultrasonic surgical blade, laser scalpel etc. can produce operation smoke.
Described display screen can select lightly portable liquid crystal display.
Described scalpel, exhaust fan, ionic migration spectrometer, display screen is all connected with control panel by circuit, control panel is provided with for controlling scalpel work or stop the scalpel switch of work, for control exhaust fan work or stop work fan switches, for the rotating speed switch of adjustment exhaust fan rotating speed, for controlling ionic migration spectrometer work or stop the ionic migration spectrometer switch of work and the display screen switch for controlling display screen, each switch can arrange separately and integrated can also be set to one-touch switch, mechanical button can be set to, the various ways such as touch-button, different colours can be adopted when each switch is arranged separately, it is convenient to distinguish, prevent mishandle. described exhaust fan is driven by its motor.
Described ionic migration spectrometer adopts existing ionic migration spectrometer. The Cleaning Principle of ion migration spectral technology be test substance molecule after vaporizer heating and gasifying, bring ionization chamber ionization into by carrier gas, then enter migration tube after there is the semi-permeable membranes of selected area update strategy function. These different types of molecules are ionized after source ionizes and form molion group, they occur migration also finally to form impulse of current on the detector with speed different separately to detector under the effect of migration tube electric field, impulse of current inputs A/D sampling thief after amplifier amplifies, transfer to data processing unit again to process, thus to produce be transverse axis taking transition time, the ion migration spectrogram that take strength of current as the longitudinal axis, spectrogram is stored in database and shows on a display screen. Owing to speed and the quality of migration, volume size and institute band electric charge are relevant, collection of illustrative plates just can distinguish different materials by the sharp peak of different positions. Owing to the relative mobility of different ions is different, so the different ions entering migration tube successively can arrive detector through migration tube simultaneously, the time that detector arrives according to different ions differentiates ionic species, the quantity of this ion is analyzed by the size of detector pulse signal, thus distinguish the kind of the raw operation smoke of excision produce, and then the carrying out of guided operation. Difference is formed significantly owing to pathological tissues cell and normal tissue cell have, the utility model can chemically molecule composition on the two is distinguished, and monitor in real time when performing the operation can be realized, distinguish pathological tissues cell and normal tissue cell in time, avoid error operation during excision. In described IMS instrument by analysis after gas directly enter its circulation device or retrieving arrangement.
Before operation, first normal tissue and pathological tissues can sample, analyze its ion migration spectrogram, take healthy tissues as standard substance. In surgical procedure, the spectrogram of the detection spectrogram of sample and healthy tissues is compared, as variant in spectrogram then judge that excision thing is as pathological tissues, need excision further, as without difference, spectrogram then judges that excision thing is as healthy tissues, it is not necessary to excise further, the carrying out of guided operation.
Compared with prior art, the utility model has following useful effect:
1, the utility model excision thing real-time detecting system, structure is simple, easily manufacture, easy to use, in the process that operation carries out, excision thing can be carried out real-time detection, the physiological status of reflection operative site directly perceived and the information of operative site surrounding environment, detected result is accurate, quick, error operation when greatly reducing excision.
2, the utility model excision thing real-time detecting system, has detectivity height, analysis time is fast, volume is little, weight is light and the feature such as low in energy consumption.
3, the utility model excision thing real-time detecting system, tissue in sample and fragment in use can be sucked together with gas and send into ionic migration spectrometer by the sampling apparatus of the integral type passage formed by the first pipeline and second pipe in the lump, ensure that the integrity of sample to greatest extent.
Accompanying drawing explanation
Fig. 1 is the structural representation of existing ionic migration spectrometer;
Fig. 2 is the structural representation of the utility model excision thing real-time detecting system.
Embodiment
Below in conjunction with accompanying drawing and embodiment, the utility model is described in further detail.
As shown in Figure 2, a kind of excision thing real-time detecting system, comprises scalpel 11, sampling apparatus 12, ionic migration spectrometer 10 and the display screen 16 for showing ionic migration spectrometer 10 detected result; Sampling apparatus 12 is for collected specimens and sample is sent to the injection port 1 of ionic migration spectrometer 10, and sampling apparatus 12 comprises the first pipeline 14 being provided with some exhaust fans 13 in pipe chamber and connects the second pipe 15 of the first pipeline 14 air inlet end and scalpel 11; The air intake surface to exhaust fan 13 is rectified in the air inlet of the first pipeline 14, and the outlet side of the first pipeline 14 is connected with the injection port 1 of ionic migration spectrometer 10; Scalpel 11 working end protrudes from the air inlet end of second pipe 15, and the bottom of scalpel 11 is fixed on the inwall of second pipe 15 air inlet end. The ionization chamber 3 of ionic migration spectrometer 10 is provided with the filtering net 17 of band ionizer.
The utility model sample comprise formed by excision thing operation smoke, one or both in scalpel surrounding environment material.
After sample enters from the injection port 1 of ionic migration spectrometer 10; can gasify through vaporizer 2 successively and ionize with ionization chamber 3; ionization chamber 3 arranges the filtering net 17 of band ionizer; can effectively be arrested on the filtering net 17 of band ionizer by a small amount of liquid that may not gasify completely in sample and solid to ionize further; can either better ensure the integrity of sample; ionic migration spectrometer 10 can be protected again, extend its work-ing life. Ionizer on filtering net 17 selects existing ionizer, can adopt the one in electron impact ionization source, chemical ionization source, fast atom bombardment source, field desorption(FD) source, electric spray ion source, atmosphere pressure chemical ion source or two or more combination.
First pipeline 14 inwall, second pipe 15 inwall and exhaust fan 13 outside surface are equipped with non-sticky metallic coating, preferably select super-hydrophobic non-sticky metallic coating, it is possible to effectively avoid sample carryover inner at sampling apparatus 12, it is to increase the accuracy of detected result. Non-sticky metallic coating can adopt existing non-sticky metallic coating, such as polytetrafluorethylecoatings coatings, ceramic coating etc.
The quantity of exhaust fan 13 can be one or two to three etc., is driven by its motor. Exhaust fan 13 is positioned at the position of the first pipeline 14 total length 1/1st to five/3rd and the outlet side of close second pipe 15, and the length of second pipe 15 is 1 times of scalpel 11 length to 1.5 times, it is possible to more effective help sampling apparatus 12 collected specimens. The duct section being provided with exhaust fan 13 in first pipeline 14 is mechanically resistant material pipeline, is convenient to the installation and use of exhaust fan 13, and remaining pipes section can adopt soft material pipeline, easy to use. Second pipe 15 is mechanically resistant material pipeline, and the use handle that can serve as scalpel 11 is convenient to the use of scalpel 11.
The connection of the injection port 1 of the connection of the first pipeline 14 air inlet end and second pipe 15 outlet side, the first pipeline 14 outlet side and ionic migration spectrometer 10 all adopts detachable connection, the internal thread cooperatively interacted as adopted and outside screw connection etc., clean after for convenience detach.
The air inlet end of second pipe 15 is horn-like, it is possible to expand the region of sampling.
The bottom of scalpel 11 and the fixing mode of second pipe 15 inwall are detachable, such as card groove, are convenient to dismounting scalpel 11, convenient cleaning scalpel 11 and second pipe 15.
The bottom of scalpel 11 is fixed on the support being located at second pipe 15 inwall, and the cutter hub of scalpel 11 is along the central shaft axial distribution of second pipe 15, the inlet mouth of annular or class annular is formed between scalpel 11 working end and second pipe 15 air inlet end sidewall, scalpel 11 working end pressed close to by inlet mouth, play the function of multi-angle, multi-faceted air-breathing, facilitate the use of medical personnel and sample can be sucked rapidly. The rack outer surface of second pipe 15 inwall scribbles non-sticky metallic coating.
Scalpel 11 comprises the surgical knife that electric knife, ultrasonic surgical blade, laser scalpel etc. can produce operation smoke. Scalpel 11 length is adjustable at 10cm-20cm, and tool bit diameter is adjustable at 0.5cm-1cm. Inlet mouth 1cm-5cm, adjustable is given prominence in scalpel 11 working end. Both it is convenient to collect various gas, does not affect again the operation of operation. Regulate in certain limit, it is possible to because of different operative sites, make different adjustment.
Display screen 16 can select lightly portable liquid crystal display.
Scalpel 11, exhaust fan 13, ionic migration spectrometer 10, display screen 16 is all connected with control panel by circuit, control panel is provided with the scalpel switch working for controlling scalpel 11 or stopping work, for control exhaust fan 13 work or stop the fan switches of work, for the rotating speed switch of adjustment exhaust fan 13 rotating speed, work for controlling ionic migration spectrometer 10 or stop the ionic migration spectrometer switch of work and the display screen switch for controlling display screen 16, each switch can arrange separately and integrated can also be set to one-touch switch, mechanical button can be set to, the various ways such as touch-button, different colours can be adopted when each switch is arranged separately, it is convenient to distinguish, prevent mishandle.
As shown in Figure 1, ionic migration spectrometer 10 adopts existing ionic migration spectrometer 10. Existing ionic migration spectrometer 10 comprises the injection port 1, the vaporizer 2 for the sample that gasifies of band high temperature heat source, the ionization chamber 3 of band ionizer, migration tube 4, detector 5, amplifier 6, A/D sampling thief 7, data processing unit 8 and the database 9 that connect successively.
When the utility model excision thing real-time detecting system uses, switch on power, open each switch on control panel, the operation smoke produced when scalpel 11 is performed the operation is inhaled into sampling apparatus 12 under the effect of exhaust fan 13, successively through second pipe 15, ionic migration spectrometer 10 is entered from the injection port of ionic migration spectrometer 10 after first pipeline 14, different types of gaseous molecular is formed after vaporizer 2 heating and gasifying in ionic migration spectrometer 10, bring ionization chamber 3 into by carrier gas and form molion group after ionizer ionizes, molion group enters migration tube 4 after having the semi-permeable membranes of selected area update strategy function, these molions group occurs migration also finally to form impulse of current on detector 5 with speed different separately to detector 5 under the effect of migration tube 4 electric field, impulse of current inputs A/D sampling thief 7 after amplifier 6 amplifies, transfer to data processing unit 8 again to process, thus produce taking transition time to be transverse axis, take strength of current as the ion migration spectrogram of the longitudinal axis, spectrogram is stored in database 9 and shows on display screen 16. owing to speed and the quality of migration, volume size and institute band electric charge are relevant, collection of illustrative plates just can distinguish different materials by the sharp peak of different positions. owing to the relative mobility of different ions is different, so the different ions entering migration tube 4 can successively arrive detector 5 through migration tube 4 simultaneously, the time that detector 5 arrives according to different ions differentiates ionic species, the quantity of this ion is analyzed by the size of detector 5 pulse signal, thus distinguish the kind of the raw operation smoke of excision produce, and then the carrying out of guided operation. difference is formed significantly owing to pathological tissues cell and normal tissue cell have, the utility model can chemically molecule composition on the two is distinguished, and monitor in real time when performing the operation can be realized, distinguish pathological tissues cell and normal tissue cell in time, avoid error operation during excision. in IMS instrument 10 by analysis after gas directly enter its circulation device or retrieving arrangement.
Before operation, first normal tissue and pathological tissues can sample, analyze its ion migration spectrogram, take healthy tissues as standard substance. In surgical procedure, the spectrogram of the detection spectrogram of sample and healthy tissues is compared, as variant in spectrogram then judge that excision thing is as pathological tissues, need excision further, as without difference, spectrogram then judges that excision thing is as healthy tissues, it is not necessary to excise further, the carrying out of guided operation.
Claims (10)
1. an excision thing real-time detecting system, it is characterised in that, comprise scalpel, sampling apparatus, ionic migration spectrometer and the display screen for showing ionic migration spectrometer detected result; Described sampling apparatus is used for collected specimens and sample is sent to the injection port of ionic migration spectrometer, and sampling apparatus comprises the first pipeline being provided with some exhaust fans in pipe chamber and connects the second pipe of the first pipeline air-inlet end and scalpel; The air intake surface to exhaust fan is rectified in the air inlet of described first pipeline, and the outlet side of the first pipeline is connected with the injection port of ionic migration spectrometer; The working end of described scalpel protrudes from the air inlet end of second pipe, and the bottom of scalpel is fixed on the inwall of second pipe air inlet end; The ionization chamber of described ionic migration spectrometer is provided with the filtering net of band ionizer.
2. excision thing real-time detecting system according to claim 1, it is characterised in that, described first inner-walls of duct, second pipe inwall and exhaust fan outside surface are equipped with non-sticky metallic coating.
3. excision thing real-time detecting system according to claim 2, it is characterised in that, described non-sticky metallic coating is super-hydrophobic non-sticky metallic coating.
4. excision thing real-time detecting system according to claim 1, it is characterised in that, described exhaust fan is positioned at the position of the first pipeline total length 1/1st to five/3rd and the outlet side of close described second pipe.
5. excision thing real-time detecting system according to claim 1, it is characterised in that, the length of described second pipe is 1 times of scalpel length to 1.5 times.
6. excision thing real-time detecting system according to claim 1, it is characterised in that, the duct section being provided with exhaust fan in described first pipeline is mechanically resistant material pipeline, and remaining pipes section is soft material pipeline; Described second pipe is mechanically resistant material pipeline.
7. excision thing real-time detecting system according to claim 1, it is characterised in that, the connection of the connection of described first pipeline air-inlet end and second pipe outlet side, the first pipeline outlet side and ionic migration spectrometer injection port all adopts detachable connection.
8. excision thing real-time detecting system according to claim 1, it is characterised in that, the air inlet end of described second pipe is horn-like.
9. excision thing real-time detecting system according to claim 1, it is characterised in that, the bottom of described scalpel and the fixing mode of second pipe inwall are detachable.
10. excision thing real-time detecting system according to claim 1, it is characterized in that, the described ionizer on filtering net is the one in electron impact ionization source, chemical ionization source, fast atom bombardment source, field desorption(FD) source, electric spray ion source, atmosphere pressure chemical ion source or two or more combination.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520942827.4U CN205280649U (en) | 2015-11-24 | 2015-11-24 | Excision thing real -time detection system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201520942827.4U CN205280649U (en) | 2015-11-24 | 2015-11-24 | Excision thing real -time detection system |
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| Publication Number | Publication Date |
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| CN205280649U true CN205280649U (en) | 2016-06-01 |
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| CN201520942827.4U Active CN205280649U (en) | 2015-11-24 | 2015-11-24 | Excision thing real -time detection system |
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