CN205263097U - Immunochromatographic test strip - Google Patents

Immunochromatographic test strip Download PDF

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Publication number
CN205263097U
CN205263097U CN201521015481.XU CN201521015481U CN205263097U CN 205263097 U CN205263097 U CN 205263097U CN 201521015481 U CN201521015481 U CN 201521015481U CN 205263097 U CN205263097 U CN 205263097U
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China
Prior art keywords
sample
plastic casing
test strip
drainage groove
immunity
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CN201521015481.XU
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Chinese (zh)
Inventor
聂海龙
吉翔
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Sinocare Inc
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Sinocare Inc
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Priority to CN201521015481.XU priority Critical patent/CN205263097U/en
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Abstract

The utility model discloses an immunochromatographic test strip, including the plastic casing that is provided with the application of sample hole with observe the hole, still including setting up in inside sample pads, gold mark pad, nitrocellulose membranes and pads that absorb water of plastic casing, sample pads shelters from and compresses tightly the cooperation in the bottom in application of sample hole and with the plastic casing, and the plastic casing is including the drainage recess that is located the sample side of stacking up, and subsides that the drainage recess is plastic casing and sample pad are partial fretwork part tightly. Through processing drainage recess between plastic casing and sample pad, increase sample pad and the external especially area of contact of sample, make the sample can evenly distributed in sample pad, the redissolution effect that the sample stacked up has been optimized at the sample, the degree of accuracy of test result has improved, set up the degree that compresses tightly that the drainage recess has still reduced plastic casing and sample pad indirectly simultaneously, make when adding the sample residual gas in the application of sample hole to discharge more easily, the sample is absorbed by the sample pad more easily, the mobile speed of sample in immunochromatographic test strip has been improved.

Description

A kind of immunity-chromatography test strip
Technical field
The utility model relates to technical field of medical detection, more particularly, relates to a kind of immunity-chromatography testBar.
Background technology
Immunochromatographic method, because it is simple and quick, does not need to coordinate special installation can complete in batchesTesting, thereby be widely used in part inspection or quarantine mechanism, immunity-chromatography test strip isA kind of conventional device that has utilized comparatively intuitively the method.
Immunity-chromatography test strip relatively simple for structure, the functional laminated structure by each level is to sampleCarry out stepwise disposal, obtain the final chromatography state of sample and analyze for coherent detection or quarantine functionary, obtainWhether sample thief is in effective informations such as normal conditions. Wherein, sample adds in examination bar by well,Sample contacts with sample pad by after well, and sample pad absorbs sample, then carries out follow-upRelated procedure, as can be seen here, well is very important with coordinating of sample pad.
There is at present a kind of comparatively conventional immunity-chromatography test strip, in order to prevent that sample from leaking on examination barLiquid phenomenon, prevents that sample from flowing into examination bar outside the scope at sample pad place, by outside the plastics of examination barShell and sample pad compression fit, namely the bottom surface of well and sample pad be close to ensure plastic casing andThe fiting effect of sample pad. Adopt above-mentioned immunity-chromatography test strip, the model of well in adding sampleEnclose the residual too much gas of interior meeting and be difficult to and discharge, the speed that causes sample to flow into examination bar is even sent out slowly very muchRaw trapping phenomena, and sample is difficult to fully contact with sample pad, causes the sample distribution in sample padInequality, the material therefore applying in sample pad can not be fully and sample complete redissolution, thereby impact examination barThe accuracy of whole test result. Meanwhile, if the viscosity of sample is larger, such as whole blood sample etc., adoptAbove-mentioned immunity-chromatography test strip very likely causes well to be stopped up by sample, thereby cannot complete sampleImmunochromatography detects.
In sum, how effectively to solve sample flow rate slowly and be difficult to be uniformly distributed and draw in sample padThe problems such as the low and testing result of detection efficiency that rises is inaccurate are that current those skilled in the art are badly in need of solvingProblem.
Utility model content
In view of this, the purpose of this utility model is to provide a kind of immunity-chromatography test strip, this immunochromatographyThe structural design of examination bar can effectively solve sample flow rate slowly and be difficult to be uniformly distributed and draw in sample padThe problems such as the low and testing result of detection efficiency that rises is inaccurate.
In order to achieve the above object, the utility model provides following technical scheme:
A kind of immunity-chromatography test strip, comprises the plastic casing that is provided with well and peep hole, also comprises and establishingThe sample pad, gold mark pad, nitrocellulose filter and the adsorptive pads that are placed in plastic casing inside, sample pad hidesBe blocked in the bottom of well and with plastic casing compression fit, plastic casing comprises and is positioned at sample pad topDrainage groove, drainage groove is the openwork part that is adjacent to part of plastic casing and sample pad.
Preferably, in above-mentioned immunity-chromatography test strip, drainage groove is symmetricly set in the periphery of well, drawsStream groove is communicated with well.
Preferably, in above-mentioned immunity-chromatography test strip, drainage groove comprises the prism groove that covers well bottom surfaceOr the cylinder groove coaxial with well.
Preferably, in above-mentioned immunity-chromatography test strip, the outer side edges of drainage groove and the outer side edges pair of sample padTogether, the outer side edges of drainage groove and the outer side edges of sample pad are tightly connected.
Preferably, in above-mentioned immunity-chromatography test strip, the outer incline of drainage groove is specially chamfering rib or filletRib.
Preferably, in above-mentioned immunity-chromatography test strip, the thickness of drainage groove is suitable mutually with the thickness of plastic casingShould, concrete scope is 0.05 to 0.2 millimeter (comprising endpoint value).
Preferably, in above-mentioned immunity-chromatography test strip, the profile of well the first half is specially inverted circlePlatform, the profile of well the latter half is specially the round platform with the profile symmetry of the first half.
A kind of immunity-chromatography test strip, comprises the plastic casing that is provided with well and peep hole, also comprises and establishingThe sample pad, gold mark pad, nitrocellulose filter and the adsorptive pads that are placed in plastic casing inside, sample pad hidesBe blocked in the bottom of well and with plastic casing compression fit, plastic casing comprises and is positioned at sample pad topDrainage groove, drainage groove is the openwork part that is adjacent to part of plastic casing and sample pad. Apply this realityWith the novel immunity-chromatography test strip providing, by process drainage groove between plastic casing and sample pad,Increase the area that sample pad can contact with the external world especially sample, made sample in absorbed processIn can be evenly distributed in sample pad, optimized the answering in sample pad of the special component in sampleMolten effect, the degree of accuracy that has improved immunity-chromatography test strip test result arranges drainage groove also indirect simultaneouslyReduce the compression degree of plastic casing and sample pad, made adding in sample residual in wellResidual air body is more easily discharged, thereby sample also just more easily absorbs by sample pad, makes this immunity-chromatography testBar is more applicable for the situation that detects the sample that viscosity is larger, has effectively improved sample at immunity-chromatography test stripIn flowing velocity, also reduced sample and stopped up the probability of well, in addition, on plastic casing, processGo out corresponding drainage groove and can also play the effect that reduces the required material of processing plastic shell, savedThe production cost of immunity-chromatography test strip.
Brief description of the drawings
In order to be illustrated more clearly in the utility model embodiment or technical scheme of the prior art, below willAccompanying drawing to required use in embodiment or description of the Prior Art is briefly described, apparently,Accompanying drawing in the following describes is only embodiment more of the present utility model, for ordinary skill peopleMember, is not paying under the prerequisite of creative work, can also obtain the attached of other according to these accompanying drawingsFigure.
The main TV structure schematic diagram of the immunity-chromatography test strip that Fig. 1 provides for the utility model embodiment;
The plan structure schematic diagram of the immunity-chromatography test strip that Fig. 2 provides for the utility model embodiment.
In accompanying drawing, mark is as follows:
Plastic casing 1, well 2, drainage groove 3, sample pad 4, gold mark pad 5, nitrocellulose filter 6,Peep hole 7, adsorptive pads 8, examination bar detection line 9, examination bar are accused line 10.
Detailed description of the invention
The utility model embodiment discloses a kind of immunity-chromatography test strip, to avoid plastic casing and sample padExtruding tension, improves speed and the uniformity that sample is absorbed by sample pad.
Below in conjunction with the accompanying drawing in the utility model embodiment, to the technology in the utility model embodimentScheme is clearly and completely described, and obviously, described embodiment is only one of the utility modelDivide embodiment, instead of whole embodiment. Based on the embodiment in the utility model, this area is commonTechnical staff is not making the every other embodiment obtaining under creative work prerequisite, all belongs to thisThe scope of utility model protection.
Refer to Fig. 1 and Fig. 2, Fig. 1 looks knot for the master of the immunity-chromatography test strip that the utility model embodiment providesStructure schematic diagram, the plan structure schematic diagram of the immunity-chromatography test strip that Fig. 2 provides for the utility model embodiment.
Embodiment of the present utility model provides a kind of immunity-chromatography test strip, comprises being provided with well 2 and seeingExamine the plastic casing 1 in hole 7, can observe sample when the inner chromatography of immunity-chromatography test strip by peep hole 7Accuse with examination bar detection line 9 and examination bar that the corresponding state of line 10, immunity-chromatography test strip also comprise and be arranged at plasticsSample pad 4, gold mark pad 5, nitrocellulose filter 6 and the adsorptive pads 8 of shell 1 inside, sample pad 4 is blockedIn the bottom of well 2 and with plastic casing 1 compression fit, in order to prevent that sample from occurring beyond sample pad 4The bleed situation of immunity-chromatography test strip of scope, the coverage of sample pad 4 must be more than or equal to application of sampleThe scope at the place, foundation ring in hole 2, plastic casing 1 comprises the drainage groove 3 that is positioned at sample pad 4 tops, drainageThe scope of groove 3 will exceed the spatial dimension at well 2 places, and drainage groove 3 is plastic casing 1 and sampleThe openwork part that is adjacent to part of pad 4, the non-openwork part that is adjacent to part is still adjacent to and coordinates with sample pad 4.
The immunity-chromatography test strip that application above-described embodiment provides, by between plastic casing 1 and sample pad 4Process drainage groove 3, increased sample pad 4 can with the contact area in the external world especially sample, makeSample can be evenly distributed in sample pad 4 in absorbed process, optimized specific in sampleThe redissolution effect of composition in sample pad 4, the degree of accuracy that has improved immunity-chromatography test strip test result, simultaneouslyThe compression degree that drainage groove 3 has also reduced plastic casing 1 and sample pad 4 is indirectly set, makes adding sampleResidual gas when product in well 2 is more easily discharged, thereby sample is also just more easily by sample pad 4Absorb, make this immunity-chromatography test strip be more applicable for the situation that detects the sample that viscosity is larger, effectively carryThe high flowing velocity of sample in immunity-chromatography test strip, has also reduced sample and has stopped up the probability of well 2,In addition, on plastic casing 1, process corresponding drainage groove 3 and can also play minimizing processing plastic shell 1The effect of required material, has saved the production cost of immunity-chromatography test strip.
In order to optimize the result of use of drainage groove 3 in above-described embodiment, drainage groove 3 is symmetricly set in and addsThe periphery in sample hole 2, drainage groove 3 can preferably have cuboid profile, and parallel immunity is preferably setChromatography tries the length direction of bar and is parallel to symmetrically arranged totally four the drainage grooves 3 of width, drainageGroove 3 is communicated with well 2. By symmetrically arranged drainage groove 3, sample is drained to the each of sample pad 4Individual direction, can be evenly distributed in sample pad 4 sample, and preferably four drainage grooves 3 form tenCabinet frame profile, has expanded the contact area of sample and sample pad 4 to a certain extent, can also not affect sampleUnder the prerequisite of the sealing of pad 4 and plastic casing 1, make sample obtain sprawling more uniformly and absorbing, improvedThe infiltration rate of sample and uniformity coefficient.
In order further to optimize the result of use of the drainage groove 3 in above-described embodiment, drainage groove 3 comprisesCover the prism groove of well 2 bottom surfaces or the cylinder groove coaxial with well 2. To moulding of well 2 bottom perimetersMaterial shell 1 carries out the hollow out processing of global shape, further expands the contact area of sample and sample pad 4,Can make sample be absorbed faster, prism groove or cylinder groove have increased the sky of well 2 bottoms simultaneouslyBetween volume, while adding sample, can not produce too much residual gas, and a small amount of residual gas is passableDischarge more easily. Certainly, the profile of drainage groove 3 can freely be selected according to the needs of practical application,As long as without prejudice to expand sample and sample pad 4 contact area object and can there is not sample and avoid sampleThe bleed phenomenon of immunity-chromatography test strip of product pad.
In order to optimize the result of use of the drainage groove 3 in above-described embodiment, the outer side edges of drainage groove 3 withThe outer side edges alignment of sample pad 4, the bottom surface edge of opening of drainage groove 3 just with the outmost turns of sample pad 4Alignment, the outer side edges of the outer side edges of drainage groove 3 and sample pad 4 is tightly connected. The present embodiment is in concrete realityExecute in process, the bottom opening area of drainage groove 3 has reached maximum, and the outmost turns of sample pad 4 justThe edge of opening of laminating drainage groove 3, the four corner that said structure feature makes sample pad 4 all can be withSample fully contacts, thus sample also just quite large degree with sample pad 4 even contact, thereby can be bySample pad 4 absorbs comparatively uniformly. Certainly, in order to prevent that sample from occurring to leak from sample pad 4 scope in additionEnter the situation of immunity-chromatography test strip, the outmost turns that sample pad 4 coordinates with drainage groove 3 need to be tightly connected,Can effectively avoid sample to absorb the situation that just enters this immunity-chromatography test strip without sample pad 4.
In order further to optimize the result of use of the drainage groove 3 in above-described embodiment, outside drainage groove 3Incline is specially chamfering rib or rounded edges. The present embodiment is in specific implementation process, by drainage groove 3Outer incline chamfering or fillet structure are set, making also can be very abundant at edge's sample of drainage groove 3Contact with sample pad 4, in the case of can not continuing to increase the area coverage of drainage groove 3, Ke YiyouEffect improves sample pad 4 and absorbs the speed of sample, further optimized sample pad 4 and absorb the effect of sample.
In order to optimize the result of use of the drainage groove 3 in above-described embodiment, the thickness of drainage groove 3 with mouldThe thickness of material shell 1 adapts, and the thickness of drainage groove 3 should be no more than the thickness of plastic casing 1, concrete modelEnclose is 0.05 to 0.2 millimeter (comprising endpoint value). In the time need to increasing the bottom space volume of well 2,Yes is the bigger the better for the one-tenth-value thickness 1/10 of drainage groove 3, but consider plastic casing 1 self thickness andThe complexity of processing drainage groove 3, the concrete infiltration rate while also having sample pad 4 to absorb different sample,The one-tenth-value thickness 1/10 of drainage groove 3 should be an optional scope, and we are preferably 0.05 millimeter to 0.2 milli hereRice, comprises endpoint value. The present embodiment, in specific implementation process, needs drainage according to actual needs recessedThe free Choice and process of groove 3 thickness, to reach the object of taking into account processing cost and actual drainage effect.
In order to optimize the result of use of well 2 in above-described embodiment, the profile tool of well 2 the first halfBody is inverted round platform, and the profile of well 2 the latter halfs is specially the circle with the profile symmetry of the first halfPlatform. The top of well 2 is for adding sample to immunity-chromatography test strip, and therefore profile is set to inverted circlePlatform can, so that sample flows in well 2, increase the speed of sample inflow well 2, well 2The latter half is the contact area with sample for increasing sample pad 4, and being therefore set to round platform can effectively reachAbove-mentioned purpose, upper the latter half is symmetrical arranged the processing of being convenient to well 2, also makes this immunity-chromatography testBar is more attractive in appearance.
In this description, each embodiment adopts the mode of going forward one by one to describe, and each embodiment stressesBe and the difference of other embodiment, between each embodiment identical similar part mutually referring to.
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field can be realized or useThe utility model. To be aobvious for those skilled in the art to the multiple amendment of these embodimentAnd easily see, General Principle as defined herein can not depart from spirit or scope of the present utility modelSituation under, in other embodiments realize. Therefore, the utility model will can not be restricted to institute hereinThese embodiment that show, but to meet consistent with principle disclosed herein and features of novelty the widestScope.

Claims (7)

1. an immunity-chromatography test strip, comprises outside the plastics that are provided with well (2) and peep hole (7)Shell (1), also comprise be arranged at the inner sample pad (4) of described plastic casing (1), gold mark pad (5),Nitrocellulose filter (6) and adsorptive pads (8), described sample pad (4) is blocked in described well (2)Bottom and with described plastic casing (1) compression fit, it is characterized in that described plastic casing (1)Comprise the drainage groove (3) that is positioned at described sample pad (4) top, described in described drainage groove (3) isThe openwork part that is adjacent to part of plastic casing (1) and described sample pad (4).
2. immunity-chromatography test strip according to claim 1, is characterized in that, described drainage groove (3)Be symmetricly set in the periphery of described well (2), described drainage groove (3) and described well (2)Be communicated with.
3. immunity-chromatography test strip according to claim 2, is characterized in that, described drainage groove (3)Comprise and cover the prism groove of described well (2) bottom surface or the cylinder groove coaxial with described well (2).
4. immunity-chromatography test strip according to claim 3, is characterized in that, described drainage groove (3)Outer side edges align with the outer side edges of described sample pad (4), the outer side edges of described drainage groove (3) withThe outer side edges of described sample pad (4) is tightly connected.
5. according to the immunity-chromatography test strip described in claim 2 to 4 any one, it is characterized in that, described inThe outer incline of drainage groove (3) is specially chamfering rib or rounded edges.
6. immunity-chromatography test strip according to claim 5, is characterized in that, described drainage groove (3)Thickness and the thickness of described plastic casing (1) adapt, concrete scope is 0.05 to 0.2 millimeter, bagDraw together endpoint value.
7. immunity-chromatography test strip according to claim 1, is characterized in that, described well (2)The profile of the first half is specially inverted round platform, and the profile of described well (2) the latter half is speciallyRound platform with the profile symmetry of described the first half.
CN201521015481.XU 2015-12-09 2015-12-09 Immunochromatographic test strip Active CN205263097U (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106771159A (en) * 2016-12-01 2017-05-31 无锡艾科瑞思产品设计与研究有限公司 A kind of Florfenicol Rapid detection test strip
CN108469521A (en) * 2018-06-29 2018-08-31 深圳加美生物有限公司 A kind of whole blood quantitatively detects device for immunochromatography entirely
CN115103722A (en) * 2020-02-14 2022-09-23 科宝智慧医疗科技(上海)有限公司 Container for liquid analysis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106771159A (en) * 2016-12-01 2017-05-31 无锡艾科瑞思产品设计与研究有限公司 A kind of Florfenicol Rapid detection test strip
CN106771159B (en) * 2016-12-01 2019-05-28 无锡艾科瑞思产品设计与研究有限公司 A kind of Florfenicol Rapid detection test strip
CN108469521A (en) * 2018-06-29 2018-08-31 深圳加美生物有限公司 A kind of whole blood quantitatively detects device for immunochromatography entirely
CN115103722A (en) * 2020-02-14 2022-09-23 科宝智慧医疗科技(上海)有限公司 Container for liquid analysis
CN115103722B (en) * 2020-02-14 2024-05-03 科宝智慧医疗科技(上海)有限公司 Container for liquid analysis

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