CN205073370U - Blood processing filter - Google Patents

Abstract

The utility model provides a blood processing filter. Adopt this blood processing filter, can avoid easily deviating the risk that specific locations leads to not good composition to get rid of insufficiently because of filter element when making blood processing filter. This blood processing filter includes: a filter elemen. And entrance side container component and outlet side container component, separating filter element between them, filter element has: a pair of filtering surface that crosses, and the terminal surface, it is equipped with the handle part along a pair of periphery of crossing filtering surface at entrance side container member and outlet side container member, and this handle part gets up a pair of outer marginal part centre gripping of crossing filtering surface and compress, is equipped with wall portion at outlet side container member, and this wall inferior officer filter element's terminal surface surrounds, and wall portion has: the opposite face, it is relative with the terminal surface, and the jut, it is outstanding from the opposite face for guide filter element is to the installation of container inside.

Description

Blood processing filter

Technical field

This utility model relates to a kind of blood processing filter, and this blood processing filter is used for removing the bad composition such as condensation product, leukocyte from comprising the liquid of blood constituent or blood.Particularly relate to a kind of disposable blood processing filters, this disposable blood processing filters is used for removal from the whole blood preparation, erythrocyte preparation, platelet transfusion, blood plasma preparation etc. of blood transfusion can cause small condensation product, the leukocyte of side effect.

Background technology

Be generally become the blood component preparations such as erythrocyte preparation, platelet transfusion, blood plasma preparation by extracting the separation of whole blood come from blood donors at present, and they be in store, afterwards for blood transfusion.Small condensation product contained by these Blood Preparationses, leukocyte can cause various transfusion adverse effects, therefore, and method such below many employings: before blood transfusion, these bad compositions are removed, transfuse blood again afterwards; Or, after blood drawing, remove these bad compositions, again preparation is temporarily saved afterwards, transfuse blood with the preparation that this saves.

As the method for removing these bad compositions from Blood Preparations, modal is process Blood Preparations with blood processing filter.The following two kinds of blood processing filters of usual use: a kind of by comprising non-woven fabrics, the filter cell of porous plastid is built in the such as flexible container shown in patent documentation 1 ~ patent documentation 5 and makes, this filter cell is built in the rigid container of Merlon etc. and makes by another kind.

When processing Blood Preparations with blood processing filter, usually, the Blood Preparations bag of the Blood Preparations be equipped with as handling object is connected in the porch of blood processing filter, and Blood Preparations bag is placed in the position than blood processing filter height about 20cm ~ 100cm, thus, Blood Preparations is made to import from Blood Preparations bag to blood processing filter under gravity.On the other hand, the reclaiming bag for the Blood Preparations after receiving filtration is connected in the exit of blood processing filter, and reclaiming bag is placed in the position of about 50cm ~ 100cm lower than blood processing filter, thus, make the Blood Preparations after filtration be accommodated in reclaiming bag under gravity.Now, in the container of blood processing filter, produced the pressure loss by the space of entrance side because of the resistance of filter cell than filter cell, thus in barotropic state.On the other hand, in the container of blood processing filter, flow out from exit because of Blood Preparations, therefore conversely in negative pressure state than the space of filter cell by outlet side.

With regard to the blood processing filter of the employing flexible container shown in patent documentation 1 ~ patent documentation 5, because container has flexibility, therefore, because the space by entrance side is that therefore malleation can make container be that balloon-like is heaved, further, filter cell is pressed towards the outlet side of container.On the other hand, because the space by outlet side is that therefore negative pressure can make container be attached on filter cell, thus the peristome of outlet is made to be by the state sealed.That is, although blood will flow out in filter, because peristome is sealed, therefore blood is difficult to flow out.

In contrast, to adopting the blood processing filter made of rigid container, also can not occur to be out of shape largely in the process of filtering, and, also there will not be filter cell be pressed towards outlet side, outlet peristome by the state sealed.Such rigid container forms by entrance side container member and outlet side container member being fitted together to, by the protuberance pressing each other of the ribbed by being located at entrance side container member and outlet side container member respectively, the outer edge of filter cell is sandwiched.By compressing to high-density protuberance, can prevent blood cross filter cell outer edge and by such side leakage (effluent) phenomenon under the state be not filtered.

Manufacture method as above-mentioned blood processing filter has a kind of such method: prepare a pair container member, this a pair container member is made by injection moulding in advance, one of them container member has blood entry port, another container member has blood outlet, filter material is clipped between said vesse component, afterwards container member is docked each other, and ul-trasonic irradiation is welded in the interface of container member.But in above-mentioned such filter making methods, except the injection moulding operation of container member, also need the operation of container member being carried out to ultrasonic bonding in addition, like this, not only make manufacturing process become loaded down with trivial details, cost also can increase.And, for ultrasonic welding method, there is the tendency that the intensity of bonding part is more weak.And, because blood processing filter is closely bound up with the Blood Preparations of human body to be transfused to, therefore, require that in order to ensure higher strainability this welding portion has the air-tightness and fluid tight of height, but, for ultrasonic welding method, container member can be caused to produce distortion, cause producing bubble etc. because of ultrasound wave vibration, thus, be short of to some extent in above-mentioned air-tightness and fluid-tight precision, need in operation afterwards, arrange the such detection operation of leak test, and the filter that there is leakage problem is excluded.

On the other hand, the manufacture method of the blood processing filter expected as the problem in view of above-mentioned conventional art has the insert molding method for making shown in patent documentation 6.In insert molding method for making, use one group of mould, to be shaped a pair container member in male-female relationship by injection moulding, wherein, this group of mould is made into a die forming female container member that can utilize in this group mould, can utilize another die forming male form container member.Afterwards, filter material is seated in one of them container member, afterwards, move moulds and make the container member in male-female relationship dock and be fitted together to, then via the resin stream of mould towards container member fitting portion and periphery injecting molten resin, thus with molten resin in zonally the whole periphery of the fitting portion of the container member in male-female relationship being bonded together.

By adopting means above, with molten resin in zonally the telescoping part of container member in male-female relationship and the complete cycle of periphery being bonded together, the air-tightness, fluid tight of height can be guaranteed, its result, can provide a kind of blood processing filter higher for the safety aspect reliability of human body.And, a kind of such manufacture method can also be provided below: by means of only use one group of mould and 1 injection (mo(u)lding) machine, just can be carried out continuously from injection molding container component by single operation, embed filter material, this series of process to a pair container member is joined together, not only bonding process can not be needed, but also the risk occurring defect ware can be reduced, and with low cost.In above-mentioned such insert molding method for making, under normal conditions, mould is swing cover type mould, and filter material to be embedded embeds male form container member or female container member from side, afterwards, the container member in male-female relationship is fitted together to and is joined together.

Prior art document

Patent documentation

Patent documentation 1: Japanese Unexamined Patent Publication 11-216179 publication

Patent documentation 2: Japanese Unexamined Patent Publication 7-267871 publication

Patent documentation 3: International Publication No. 2004/050147 handbook

Patent documentation 4: International Publication No. 95/17236 handbook

Patent documentation 5: European Patent application discloses No. 0526678 description

Patent documentation 6: Japanese Unexamined Patent Publication 2001-226271 publication

Utility model content

The problem that utility model will solve

But, in method for making in the past, after the operation between entrance side container member and outlet side container member such as the container member that will be clipped in as the filter cell of filter material in male-female relationship, filter cell can misplace sometimes, thus manufacture filter in go wrong.Particularly, when there is dislocation in filter cell, ought to can be become and easily departed from because filter cell dislocation by the outer edge of the filter cell of entrance side container member and the clamping of outlet side container member, thus may occur blood cross filter cell outer edge and by such side leakage (effluent) under the state be not filtered.And, manufacturing in the manufacture method of filter above by insert molding, sometimes when filter cell is inserted between container member, male form container member and female container member are vertically erect, in this case, when filter cell being embedded male form container member or female container member, because action of gravity is on the in-plane of filter cell, therefore filter cell easily misplaces.

Namely this utility model is made to solve the problem, its object is to, a kind of blood processing filter is provided, adopting this blood processing filter, can easily avoiding because filter cell departs from assigned position and causes the risk that bad composition is removed insufficient when manufacturing blood processing filter.

For the scheme of dealing with problems

Invention people have carried out deep research to solve the problem, found that, be used for making filter cell aim at the component of the appropriate location of internal tank when loading filter cell by arranging, such as jut is set, can reliably prevent filter cell from misplacing, and complete this utility model.

That is, this utility model is a kind of blood processing filter, and it is for removing bad composition from comprising in the liquid of blood constituent or blood, and wherein, this blood processing filter comprises: the filter cell of lamellar; And container, it has entrance side container member and outlet side container member, across filter cell between entrance side container member and outlet side container member, the inner space of this container is become entrance space and outlet space by filter element separate, filter cell has: a pair filtering surface, and they are configured in entrance space side and outlet space side respectively; And end face, it is along the periphery of a pair filtering surface, handle part is provided with at entrance side container member and outlet side container member, this handle part is used for the clamping of the outer edge of a pair filtering surface get up and compress, at least one in entrance side container member and outlet side container member is provided with wall portion, the end face of filter cell is surrounded by this wall portion, and wall portion has: opposite face, and it is relative with end face; And jut, it is given prominence to from opposite face, for being led through the installation of filter element to internal tank.In addition, the blood in this utility model comprises the Blood Preparations such as whole blood preparation, erythrocyte preparation, platelet transfusion, blood plasma preparation of blood transfusion.

And, according to above-mentioned blood processing filter, also can be, jut has tapered portion, and this tapered portion is used for being led through filter element from the tip side of wall portion to base end side, and tapered portion has inclined-plane, the overhang of the tip side by wall portion on this inclined-plane is less, and the overhang by base end side is larger.Adopt this blood processing filter, the inclined-plane of tapered portion can be utilized to be led through filter element swimmingly.

Particularly, when the angle of inclination on this inclined-plane is greater than 60 ° with the opposite face of wall portion for benchmark, when loading yielding, more soft filter cell, easy and jut occurs disturb and be crushed, therefore, being preferably less than 60 °, is more preferably less than 45 °, be further preferably less than 40 °, be more preferably less than 35 ° further.

And according to above-mentioned blood processing filter, also can be, tapered portion has multiple inclined-plane, and the angle of inclination by the inclined-plane of the tip side of wall portion is greater than the angle of inclination on the inclined-plane by base end side.By making tapered portion have multiple inclined-plane, such as, when yielding filter cell is seated in container, also filter cell can be guided to the direction that will locate at leisure, and excessive load can not be applied to filter cell.

And according to above-mentioned blood processing filter, also can be, jut has fixed part, the end face close contact of this fixed part and filter cell thus supporting filter device element, fixed part is formed in than the position of tapered portion by the base end side of wall portion.Suppose not arrange fixed part, then need to be born by tapered portion to be led through filter element and these two functions of Fixed-Filter element, and be difficult to the optimization realizing angle of inclination.But, if tapered portion and fixed part can be arranged at jut, then can realize as under type, that is, to tapered portion, make it have the angle of inclination easily allowing filter cell be configured in assigned position, conversely, to fixed part, do not consider angle of inclination, but preferentially make filter cell after filling, be in the state not easily misplaced, thus easily can realize the optimization of blood processing filter.

And according to above-mentioned blood processing filter, also can be, fixed part has the angle of inclination at the angle of inclination being less than tapered portion, the angle of inclination of fixed part is less than 10 °.When the angle of inclination of fixed part is greater than 10 °, the filter cell be before loaded into easily reverse coming off and become easy disengaging, therefore, the angle of inclination of fixed part is preferably less than 10 °, be more preferably less than 9 °, be further preferably less than 8 °, be more preferably less than 5 ° further.In addition, spend the problem such as time, generation unfavorable condition if can eliminate when the demoulding manufactures, the angle of inclination of fixed part also can be 0 °.

And, according to above-mentioned blood processing filter, also can be that the gross area that fixed part contacts with the end face of filter cell is less than 5% of the gross area of the end face of filter cell.When being greater than 5%, when being seated in rigid container by filter cell, institute's applied pressure may cause filter cell bulk deformation.Namely, be less than 5% of the gross area of the end face of filter cell by the gross area making fixed part contact with the end face of filter cell, can suitably reserve with the end face close contact of filter cell thus the part of supporting filter device element, and only supporting by a part, and the distortion occurred when filter cell can be reduced to be seated in container.And, the amount of jut material used such as resin can be cut down, thus can also reduce costs.And, be not limited thereto, as long as can filter cell be held, and the distortion occurred when filter cell can be reduced to be seated in container, the gross area that fixed part contacts with the end face of filter cell also can be less than 3% or less than 2% of the gross area of the end face of filter cell.

And, according to above-mentioned blood processing filter, also can be that the summation of the width that fixed part contacts with the end face of filter cell is less than 15% of the periphery length of filter cell.When being greater than 15%, when being loaded in a reservoir by filter cell, institute's applied pressure may cause filter cell bulk deformation, thus can hinder filter cell aligned position rightly.Namely, the summation of the width contacted with the end face of filter cell by making fixed part is less than 15% of the periphery length of filter cell, suitably can reserve the width of the jut for filter cell being configured in assigned position, and can reduce because filter cell is out of shape the degree causing being difficult to aligned position.And, the amount of jut material used such as resin can be cut down, thus can also reduce costs.And, as long as can by filter cell aligned position rightly, and the distortion occurred when filter cell can be reduced to be seated in container, the summation of the width that fixed part contacts with the end face of filter cell also can be less than 10% or less than 5% of the periphery length of filter cell.

Moreover, it can be, above-mentioned jut along wall portion circumference with the empty standard width of a room in an old-style house every mode be configured with multiple.When with place's jut aligned position, filter cell, easily misplace with the contrary side of the part that jut contacts.And, if to arrange premised on multiple jut, then the jut of the quantity of the shape being suitable for blood processing filter can be configured.Consider from this angle, configure two juts and also can play a role, but preferably configure more than 3, more preferably configure more than 4.Such as when for circular blood processing filter, during jut more than configuration 3 place, easily by filter cell aligned position, be therefore preferred.And, when the blood processing filter for square or rhombus, preferably configure the jut at more than 4 places, particularly, if respectively configure in diagonal angle part the words that 2 place's juts amount to configuration 4 place jut, then filter cell can be aligned in appropriate location, thus the situation of dislocation occurs after more effectively can suppressing that filter cell is imported container.And add up to configuration 8 place jut by configuring two place's juts on each limit, filter cell is easily subject to the guiding from each bar limit of container equably, thus can, more easily by filter cell aligned position, therefore be preferred.

Moreover, it can be, above-mentioned multiple jut along the circumference of wall portion to configure at equal intervals.Its result, can be led through filter element evenly, thus effectively can prevent dislocation.

Moreover, it can be, at least one group of jut in multiple jut is oppositely disposed across filter cell.Its result, can utilize multiple jut clamping filter cells of relative configuration, thus can effectively prevent filter cell from misplacing.

Also can be that entrance side container member and outlet side container member also have fitting portion, and this fitting portion is fitted together in the mode be surrounded by the end face of filter cell, and fitting portion has wall portion.By arranging fitting portion, can easily entrance side container member be aimed at outlet side container member and they are joined together.

And, also can be, fitting portion has the entrance side fitting portion being located at entrance side container member and the outlet side fitting portion being located at outlet side container member, and the resin that is melted at least partially of the sliding contacting part between entrance side fitting portion and outlet side fitting portion is zonally be bonded together on the complete cycle of fitting portion.By being melted resin in being zonally bonded together on the complete cycle of fitting portion, thus air-tightness and fluid tight can be improved.

Moreover, it can be, be provided with resin stream at sliding contacting part, by molten resin is filled in resin stream, sliding contacting part is bonded together.By forming resin stream, molten resin not easily overflows from sliding contacting part, thus can reduce molten resin and enter probability in container.

Moreover, it can be, container is that the resin being more than 0.1GPa by the Young's modulus under room temperature is made, its result, deforms with container when filtering when can suppress to import filter cell.

The effect of utility model

Adopting this utility model, can easily avoiding because filter cell departs from assigned position and causes the risk that bad composition is removed insufficient when manufacturing blood processing filter.

Accompanying drawing explanation

Fig. 1 is the observable top view in entrance side container member side of the blood processing filter from embodiment of the present utility model.

Fig. 2 is the side view of the blood processing filter of embodiment of the present utility model.

Fig. 3 is the sectional view along III in Fig. 1-III line.

The wall portion being located at outlet side container member is amplified the sectional view represented by Fig. 4.

Fig. 5 is the axonometric chart representing the protuberance being located at wall portion.

Fig. 6 (a) ~ Fig. 6 (d) is the figure of the relation represented between filling filter cell and protuberance, wherein, Fig. 6 (a) represents that filter cell is guided by protuberance and is aligned the figure of the state of position, Fig. 6 (b) is the figure that the tilt angle theta of tapered portion and the angle of inclination δ of fixed part are described, Fig. 6 (c) is the tilt angle theta that represents tapered portion when being 60 ° and 45 ° time figure, Fig. 6 (d) is the angle of inclination δ that represents fixed part when being 10 ° and 5 ° time figure.

Fig. 7 (a) ~ Fig. 7 (d) is the top view biopsy cavity marker devices of the blood processing filter of other embodiments represented afterwards, wherein, Fig. 7 (a) is the top view of the blood processing filter representing the 2nd embodiment, Fig. 7 (b) is the top view of the blood processing filter representing the 3rd embodiment, Fig. 7 (c) is the top view of the blood processing filter representing the 4th embodiment, and Fig. 7 (d) is the top view of the blood processing filter representing the 5th embodiment.

Fig. 8 (a) ~ Fig. 8 (b) is the sectional view of the wall portion of the blood processing filter representing other embodiments, wherein, Fig. 8 (a) be represent for compare with other embodiments, the sectional view of the blood processing filter of the 1st embodiment, Fig. 8 (b) is the sectional view of the blood processing filter representing the 6th embodiment, Fig. 8 (c) is the sectional view of the blood processing filter representing the 7th embodiment, and Fig. 8 (d) is the sectional view of the blood processing filter representing the 8th embodiment.

Fig. 9 is the curve chart representing the measurement result that the thickness measuring the filter cell before and after being shaped obtains.

Figure 10 is the key diagram for illustration of the container member forming process manufactured in the blood processing filter process of embodiment.

Figure 11 is the key diagram for illustration of the filling operation manufactured in the blood processing filter process of embodiment.

Figure 12 is the key diagram for illustration of the bonding process manufactured in the blood processing filter process of embodiment of the present utility model and affixed operation.

Description of reference numerals

1,1A ~ 1G, blood processing filter; 2, filter cell; 2a, 2b, filtering surface; 2c, end face; 2d, 2e, outer edge; 3, rigid container (container); 3s, inner space; 4, entrance side container member; 4d, entrance side fitting portion; 4s, entrance space; 5, outlet side container member; 5d, outlet side fitting portion; 5s, outlet space; 6, molten resin; 7, fitting portion; 7a, sliding contacting part; 9, handle part; 12, But moving die (mould); 13, slide mobile mould (another mould); 52,52E ~ 52G, wall portion; 52d, 53d, 54d, 55d, 56d, 57d, 58d, 59d, jut; 52c, opposite face; 52e, 57e, 58e, 52p, tapered portion; S, S1 ~ S5, inclined-plane; The angle of inclination on θ, inclined-plane; The angle of inclination of δ, fixed part.

Detailed description of the invention

Below, with reference to accompanying drawing, being preferred embodiment described in detail to the manufacture method of blood processing filter of the present utility model and blood processing filter.

First, with reference to Fig. 1 ~ Fig. 3, the blood processing filter 1 of embodiment is described.Blood processing filter 1 is for from comprising the liquid of blood constituent or blood (hereinafter referred to as liquid to be treated.) in remove bad composition.

Blood processing filter 1 is overall rectangular, and it comprises filter cell 2 and the rigid container 3 of lamellar.Rigid container 3 has entrance side container member 4 and outlet side container member 5, across filter cell 2 between entrance side container member 4 and outlet side container member 5, and mutually fix up, inner space 3s is separated into entrance space 4s and outlet space 5s by filter element 2.Being provided with for liquid to be treated is imported inner ingress port 4a at entrance side container member 4, being provided with the outlet port 5a of the treatment fluid discharge for processing through filter element 2 at outlet side container member 5.In addition, blood processing filter 1 also can the arbitrary shape such as rectangular, discoid, oval tabular, but in order to reduce spillage of material during manufacture, preferably rectangle.And, can by square, that rhombus is also considered as rectangle one.And in the present embodiment, although the example of rigid container 3 as container be illustrated, container also can be have flexible flexible container.

With regard to the entrance side container member 4 of the major part as rigid container 3 and the material of outlet side container member 5, in order to deform with rigid container 3 when filtering when suppressing to import filter cell 2, the Young's modulus preferably under room temperature is the resin of more than 0.1GPa.Such as can use Merlon, polyester fiber, polyamide, polystyrene, HIPS, ABS, polyethylene, polypropylene, polrvinyl chloride etc.The Merlon etc. that more preferably thermostability is higher.In addition, for the measurement of Young's modulus, can use and carry out according to ISO527-1 the result measured.

Filter cell

Filter cell 2 can use the fibrous porous property such as non-woven fabrics, woven medium, or spongy texture thing etc. has the well-known filter mediums such as the porous plastid of the continuous pore of three dimensional network eye.These materials such as can list polypropylene, polyethylene, styreneisobutylene-styrene polymer, polyurethane, polyester fiber etc.When filter cell 2 is non-woven fabrics, consider it is particularly preferred from the angle of production efficiency.

Filter cell 2 both can be single filter cell, also can comprise multiple filter cell, and wherein, the plurality of filter cell comprises stacked multiple sheet-like filter components respectively.When comprising multiple filter cell, preferably, comprise the first filter cell and the second filter cell, wherein, first filter cell is configured in upstream, it is mainly used in removing small condensation product, and the second filter cell is configured in the downstream of the first filter cell, and it is for removing the bad composition beyond small condensation product.

Such as, the filter element that fibre diameter is the non-woven fabrics of several μm ~ tens of μm can be comprised in entrance side configuration, as being mainly used in the first filter cell removing condensation product, following configuration comprises the filter element that fibre diameter is the non-woven fabrics of 0.3 μm ~ 3.0 μm, as the second filter cell for removing the bad composition beyond condensation product.Also can be that the first filter cell, the second filter cell include the mutually different multiple filter element of fibre diameter, also can be, only the first filter cell or the second filter cell comprise multiple filter element.

Also can be such as, be that the first filter cell of the non-woven fabrics of 10 μm ~ 20 μm is configured in upstream side by comprise fibre diameter be the non-woven fabrics of 30 μm ~ 40 μm and/or fibre diameter, and in the configuration of the downstream of the first filter cell, to comprise fibre diameter be the non-woven fabrics of 1.5 μm ~ 2.5 μm and/or fibre diameter is the second filter cell of the non-woven fabrics of 0.5 μm ~ 1.8 μm, thus form filter cell 2.In addition, also can be non-woven fabrics thicker for fibre diameter and the thinner non-woven fabrics of fibre diameter are alternately configured, but preferably, the non-woven fabrics that fibre diameter is thicker is configured in upstream side.

The fitting portion of rigid container, and utilize handle part to the compression of filter cell

As mentioned above, rigid container 3 is for having the rectangular vessel of specific thickness, and it has entrance side container member 4 and outlet side container member 5, and entrance side container member 4 and outlet side container member 5 are configured to each other across filter cell 2.And the inner space 3s of rigid container 3 is separated into entrance space 4s side and outlet space 5s side by filter element 2.And filter cell 2 has the filtering surface 2a relative with entrance space 4s, the filtering surface 2b relative with outlet space 5s, and the end face 2c of periphery along a pair filtering surface 2a, 2b.

Entrance side container member 4 is the rectangular elements (with reference to Fig. 2) obtained after being cut rigid container 3 roughly half position in a thickness direction, and outlet side container member 5 is the rectangular elements of the remainder of rigid container 3.Be provided with entrance side fitting portion 4d (with reference to Fig. 3) at the periphery of entrance side container member 4, the periphery of outlet side container member 5 be provided with can with the outlet side fitting portion 5d of entrance side fitting portion 4d tabling.Entrance side fitting portion 4d and outlet side fitting portion 5d is male-female relationship, and they are fitted together in the mode be surrounded by the end face 2c of filter cell 2, thus forms fitting portion 7.In addition, in the following description, entrance side fitting portion 4d is considered as positive side, outlet side fitting portion 5d is considered as cloudy side, and in more detail fitting portion 7 is described with such example that is configured to, but this male-female relationship also can be exchanged.

In more detail fitting portion 7 is described.The entrance side fitting portion 4d of convex is provided with at the periphery of entrance side container member 4.On the other hand, be provided with wall portion 52 and seat portion 51 at the periphery of outlet side container member 5, wall portion 52 can abut and be sticked in the inner peripheral surface 42 of entrance side fitting portion 4d, and seat portion 51 can be connected to the top end face 41 of entrance side fitting portion 4d.Outlet side fitting portion 5d comprises wall portion 52 and seat portion 51.And the position contacted between entrance side fitting portion 4d with outlet side fitting portion 5d is the sliding contacting part 7a of fitting portion 7, is provided with resin stream 8 at sliding contacting part 7a.Be bonded together by the molten resin 6 be filled in resin stream 8 thus be fixed between entrance side container member 4 and outlet side container member 5.In addition, also can be, resin stream 8 is not set, and utilize ultrasonic bonding etc. to be fixed up between entrance side container member 4 and outlet side container member 5.

Resin stream 8 is that to comprise cross section be the groove 4b of letter U shape and the cavity of groove 5b, and wherein, groove 4b is located at entrance side fitting portion 4d, and groove 5b is located at outlet side fitting portion 5d.By being filled in resin stream 8 by molten resin 6, sliding contacting part 7a's is zonally be bonded together on the complete cycle of fitting portion 7 at least partially.By in this wise in being zonally bonded together on the complete cycle of fitting portion 7, rigid container 3 is sealed, thus air-tightness, fluid tight can be improved.In addition, resin stream 8 has through hole (not shown) that is inner with rigid container 3 or rigid container 3 ft connection.The quantity of through hole both can be one also can be multiple.In addition, although the resin stream 8 of present embodiment is for comprising the cavity that the groove 4b that the cross section being located at entrance side fitting portion 4d is letter U shape and the cross section being located at outlet side fitting portion 5d are both groove 5b of letter U shape, but also can be, resin stream 8 only comprise above-mentioned any one in both.

As shown in Figure 3, be provided with handle part 9 in the inner side of fitting portion 7, this handle part 9 is for getting up the table of filter cell 2 back of the body two sides i.e. outer edge 2d, 2e clamping of a pair filtering surface 2a, 2b and compress.Handle part 9 comprises the entrance side compression unit 4f being formed in entrance side the container member 4 and outlet side compression unit 5f being formed in outlet side container member 5.

Entrance side compression unit 4f is formed by stage portion, and this stage portion is bent towards inner surface side (outlet side container member 5 side) by the periphery of entrance side container member 4, then bends laterally.Similarly, outlet side compression unit 5f is also formed by stage portion, and this stage portion is bent towards inner surface side (entrance side container member 4 side) by the periphery of outlet side container member 5, then bends laterally.The table of filter cell 2 back of the body two sides i.e. outer edge 2d, 2e clamping of a pair filtering surface 2a, 2b is got up and compresses by entrance side compression unit 4f and outlet side compression unit 5f.

Handle part 9 utilize entrance side compression unit 4f and outlet side compression unit 5f to filter cell 2, from outer most edge calculate 1mm ~ 5mm width L within the scope of part compress.By making the width L by handle part 9 compresses be greater than 1mm in this wise, can prevent the filter cell 2 when being flattened by filter cell 2 from departing from handle part 9, and then the situation that bad composition removes insufficient can be prevented.And, by make utilization in actual filtration with less than the width L compressed by handle part 9 that formed of region be less than 5mm, thus to design in the scope easily allowed in the efficiency of blood treatment or in cost.

Entrance side container member 4 inner surface side, the rib 4h that is provided with multiple convex by the inside region that entrance side compression unit 4f is surrounded.And, outlet side container member 5 inner surface side, the rib 5h that is provided with multiple convex by the inside region that outlet side compression unit 5f is surrounded.The rib 4h of entrance side container member 4 presses the filtering surface 2a of filter cell 2, thus can guarantee the entrance space 4s between the inner surface of entrance side container member 4 and filtering surface 2a.Similarly, the rib 5h of outlet side container member 5 presses the filtering surface 2b of filter cell 2, thus can guarantee the outlet space 5s between the inner surface of outlet side container member 5 and filtering surface 2b.

As mentioned above, in the blood processing filter 1 of present embodiment, a pair filtering surface 2a, 2b of filter cell 2 are got up by rib 4h, 5h clamping and local is compressed, thus can guarantee entrance space 4s and outlet space 5s with effective and stable state.In addition, in the present embodiment, the thickness of the rib 4h of entrance side container member 4 is greater than rib 5h, its result, can guarantee the entrance space 4s broader than outlet space 5s.In addition, also can be, rib 4h be identical with the thickness of rib 5h, can certainly conversely, make the thickness of rib 5h be greater than rib 4h.

Need 0.05 times ~ 0.5 times that the thickness D of the filter cell 2 at handle part 9 place is compressed to original thickness D0, that is, D/D0=0.05 ~ 0.5.At this, owing to filter cell 2 cannot be compressed to below initial resin density, the situation that therefore D/D0 is less than 0.05 is difficult to realize in practical situations both.On the other hand, when D/D0 is greater than 0.5, cannot be referred to as filter cell 2 is by high density compressed state, thus produce bad composition and cross outer edge 2d, 2e of filter cell 2 and the risk of side leakage (effluent) occurs, therefore, the removal capacity for the bad composition such as leukocyte reduces.Above-mentioned side leakage is shunk caused by container because of higher temperature when carrying out steam sterilization under high temperature and high pressure environment, comparatively obviously.That is, to filter cell 2, realize the thickness D that is compressed into close to the degree of initial resin density particularly important, its result, the removal capacity for the bad composition such as leukocyte can be improved.Therefore, such as, when the original thickness D0 of filter cell 2 is 10mm, need the thickness D at handle part 9 place to be compressed to about 0.5mm ~ 5mm.And, in order to the thickness D at handle part 9 place being compressed to 0.05 times ~ 0.5 times of original thickness D0, need to adjust molding die, with 0.05 times ~ 0.5 times that makes that the distance between the distance of handle part 9 and the entrance side compression unit 4f face relative with outlet side compression unit 5f is original thickness D0.In addition, consider from the easiness and the angle improved for the removal capacity of the bad composition such as leukocyte is such taking into account manufacture view, preferably D/D0=0.07 ~ 0.45, more preferably D/D0=0.1 ~ 0.4.

Then, for the original thickness D0 of filter cell 2, situation about verifying from the blood processing filter 1 after shaping is illustrated.Blood processing filter 1 after being shaped is decomposed, to not measured by the thickness of the part held, in this case, there is the range of error of several percentage points relative to the original thickness D0 before being clamped by handle part 9 in the maximum D1 of this thickness, maximum D1 can be regarded as original thickness D0 in fact.More particularly, maximum D1 refers to: except the part except causing filter cell 2 to there occurs distortion because of the protuberance in the rigid containers such as handle part 9 or rib 4h, 5h 3 and be filter cell 2 central authorities near, not cave in etc., the maximum thickness of 5 positions choosing out in part that shape does not change, the original thickness D0 before this maximum D1 can be regarded as being clamped by handle part 9.

With reference to Fig. 9, to confirming that the experimental result of this checking is described.Fig. 9 is the section thickness for filter cell 2 (polyester non-woven fabric), the curve chart that rear with shaping before blood processing filter 1 is shaped (being decomposed by the blood processing filter 1 after being shaped) compares and obtain.As shown in Figure 9, when this blood processing filter 1, the difference of original thickness D0 and maximum D1 is about 3% of original thickness D0.That is, can confirm, the original thickness D0 of filter cell 2 with the blood processing filter 1 after being shaped is decomposed after the difference of the maximum D1 of filter cell 2 that obtains be about several percentage points of original thickness D0.In addition, for the measurement opportunity of thickness after decomposing, at once carry out the result measured after decomposition and after decomposing, to place compared with the result measured again for one week almost indifference.Thus confirm, from decomposition after to measurement time institute's elapsed time on the measurement result of thickness almost without affect.

According to result above, with grasp compared with the original thickness D0 before being shaped, in the comparatively easy situation of maximum D1 that detects the filter cell 2 obtained after being decomposed by the blood processing filter 1 after being shaped, can replace grasping thickness D0 by detecting maximum D1, and maximum D1 can be considered as original thickness D0 thus grasp the value of D/D0.Specifically, because D1 and D0 is equal, maybe should less than D0 several percentage points (namely, D0 >=D1), therefore, as long as thickness D be less than 0.5 times of maximum D1 (namely, D/D1≤0.5), then thickness D is decided to be less than 0.5 times (that is, D/D0≤0.5) of original thickness D0 with regard to one.On the other hand, owing to filter cell 2 cannot be compressed to below the density of initial resin, therefore, can think the situation being difficult to occur that lower limit is less than 0.05, thus, can think and be difficult to occur that thickness D is more than 0.05 times of maximum D1, but thickness D is less than the situation of 0.05 times of original thickness D0.That is, as long as D/D1=0.05 ~ 0.5, so just D/D0=0.05 ~ 0.5 can be considered as.

And, the difference of maximum D1 and original thickness D0 is about several percentage points of original thickness D0, therefore the degree almost can ignored is thought, but, irrefragablely be, due to this error of several percentage points, even if there is hypothesis when D/D1 > 0.5, the probability of D/D0≤0.5 during D0 can be detected actually.

Then, to the situation of D/D0=0.07 ~ 0.45, and the situation of D/D0=0.1 ~ 0.4 is described.Physically, the value of D/D0 may lower than these lower limits 0.07 and 0.1.Therefore, to can make the lower limit of D/D0 be reliably more than 0.07 and 0.1, the lower limit of D/D1 discusses.At this, suppose that maximum D1 is very large compared with the value in above-mentioned experiment (with reference to Fig. 9) with the difference of original thickness D0, be such as 10%, like this, when D/D0=0.07, D/D1=0.078 (=0.07/0.9), when D/D0=0.1, D/D1=0.11 (=0.1/0.9).That is, at least when D/D1=0.078 ~ 0.45, being considered as D/D0=0.07 ~ 0.45 is reasonable, and when D/D1=0.11 ~ 0.4, being considered as D/D0=0.1 ~ 0.4 is reasonable.

The wall portion of fitting portion

As shown in Fig. 3, Fig. 4 and Fig. 5, be provided with wall portion 52 at fitting portion 7.Wall portion 52 is can configure the mode that the end face 2c of filter cell 2 is surrounded, and it has: opposite face 52c, and it is relative with the end face 2c of filter cell 2; And jut 52d, it is outstanding towards filter cell 2 side from opposite face 52c.When being seated in outlet side container member 5 by filter cell 2, jut 52d plays the effect of appropriate location filter cell 2 being guided to outlet side container member 5 inside.In addition, when wall portion 52 is located at entrance side container member 4, when being seated in entrance side container member 4 by filter cell 2, the jut 52d being located at wall portion 52 plays the effect of appropriate location filter cell 2 being guided to entrance side container member 4 inside.

The jut 52d of present embodiment (with reference to Fig. 1) along wall portion 52 circumference with the empty standard width of a room in an old-style house every mode be provided with multiple, be particularly located in equally spaced position everywhere.More particularly, when observing from depression angle, be provided with each jut 52d, result in the centre of the part suitable with each bar limit of the blood processing filter 1 of rectangle, be formed with two groups of jut 52d groups be oppositely disposed across filter cell 2.In addition, also can be that the jut 52d group be oppositely disposed across filter cell 2 is formed with one group, in this case, remaining jut 52d is unnecessary forms as described above group, also can be configured in optional position.

As shown in Fig. 6 (a), jut 52d has tapered portion 52e, this tapered portion 52e is used for being led through filter element 2 from top (open end) 52a side direction cardinal extremity (the inside) the 52b side of wall portion 52, tapered portion 52e has inclined-plane S (with reference to Fig. 4), this inclined-plane S is less by the overhang of the 52a side, top of wall portion 52, and the overhang by cardinal extremity 52b side is larger.In addition, the local of the part by opposite face 52c side of the top 52a of wall portion 52 is cut off and defines rake 52g, this rake 52g and tapered portion 52e at grade (continuously) couple together.

As shown in Fig. 6 (b), the tilt angle theta of the inclined-plane S of tapered portion 52e be with opposite face 52c for angle of inclination during benchmark, it is desirable to be less than 60 ° (with reference to Fig. 6 (c)).When the tilt angle theta of inclined-plane S is greater than 60 °, when loading yielding, more soft filter cell 2, filter cell 2 easily and jut 52d occur disturb and be crushed.Thus, tilt angle theta is preferably less than 60 °, is more preferably less than 45 °, is further preferably less than 40 °, is more preferably less than 35 ° further.

And, as shown in Fig. 6 (a), Fig. 6 (b), jut 52d has fixed part 52f, and this fixed part 52f is formed in than the position of cardinal extremity 52b side of tapered portion 52e by wall portion 52, and can with the end face 2c close contact of filter cell 2 thus supporting filter device element 2.Fixed part 52f has the angle of inclination δ of the tilt angle theta being less than tapered portion 52e, this angle of inclination δ be with opposite face 52c for angle of inclination during benchmark, it is desirable to be less than 10 ° (with reference to Fig. 6 (d)).When the angle of inclination δ of fixed part 52f is greater than 10 °, the filter cell 2 be before loaded into is easily reverse to come off (easily departing from), therefore, the angle of inclination δ of fixed part 52f is preferably less than 10 °, be more preferably less than 9 °, be further preferably less than 8 °, be more preferably less than 5 ° further.In addition, spend the problem such as time, generation unfavorable condition if can eliminate when the demoulding manufactures, the angle of inclination δ of fixed part 52f also can be 0 °.That is, the angle of inclination δ of fixed part 52f is that less than 10 ° such scopes also comprise 0 °, that is, fixed part 52f also can be parallel with the opposite face 52c of wall portion 52 in fact.

The gross area that fixed part 52f contacts with the end face 2c of filter cell 2 is the less than 5% then better of the gross area of the end face 2c of filter cell 2.When being greater than 5%, filter cell 2 being seated in rigid container 3 time institute's applied pressure and may causing filter cell 2 bulk deformation.Namely, be less than 5% of the gross area of the end face 2c of filter cell 2 by the gross area making fixed part 52f contact with the end face 2c of filter cell 2, can suitably reserve with the end face 2c close contact of filter cell 2 and the area of the part of supporting filter device element 2, and only supporting by a part, and the distortion occurred when filter cell 2 can be reduced to be seated in rigid container 3.And, the amount of jut 52d material used such as resin can be cut down, thus can also reduce costs.In addition, as long as can suitably supporting filter device element 2, and the distortion occurred when filter cell 2 can be reduced to be seated in container, the gross area that fixed part 52f contacts with the end face 2c of filter cell 2 also can be less than 3% or less than 2% of the gross area of the end face 2c of filter cell 2.

On the other hand, the gross area that fixed part 52f contacts with the end face 2c of filter cell 2 is larger, more can prevent filling after-filter element 2 from misplacing, therefore, preferably, the gross area that fixed part 52f contacts with the end face 2c of filter cell 2 is more than 0.5% of the gross area of the end face 2c of filter cell 2, is more preferably more than 1%.

And the summation of the width that fixed part 52f contacts with the end face 2c of filter cell 2 is the less than 15% then better of the periphery length of filter cell 2.When being greater than 15%, filter cell 2 being seated in rigid container 3 time institute's applied pressure and may causing filter cell 2 bulk deformation, thus can hinder filter cell 2 aligned position rightly.Namely, the summation of the width contacted with the end face 2c of filter cell 2 by making fixed part 52f is less than 15% of the periphery length of filter cell 2, suitably can reserve the width of the jut 52d for filter cell 2 being configured in assigned position, and can reduce because filter cell 2 is out of shape the degree causing being difficult to aligned position.And, the amount of jut 52d material used such as resin can be cut down, thus can also reduce costs.And, as long as can by filter cell 2 aligned position rightly, and the distortion occurred when filter cell 2 can be reduced to be seated in container, the summation of the width that fixed part 52f contacts with the end face 2c of filter cell 2 also can be less than 10% or less than 5% of the periphery length of filter cell 2.

On the other hand, fixed part 52f is larger with the summation of the width that the end face 2c of filter cell 2 contacts, more can prevent filling after-filter element 2 from misplacing, therefore, preferably, the summation of the width that fixed part 52f contacts with the end face 2c of filter cell 2 is more than 0.5% of the periphery length of filter cell 2, is more preferably more than 1%, is further preferably more than 3%.

Then, the effect of the blood processing filter 1 of present embodiment, effect are described.With regard to this blood processing filter 1, be seated in by filter cell 2 in the operation be provided with in the outlet side container member 5 of wall portion 52, filter cell 2 is guided to inner assigned position by jut 52d, and therefore, filter cell 2 not easily misplaces.Its result, easily can realize filter cell 2 and be built in the blood processing filter 1 of rigid container 3 inside validly, therefore, it is possible to the risk that when easily avoiding using, bad composition is removed insufficient.

And, the jut 52d of various form can be dreamed up, the jut 52d of present embodiment has tapered portion 52e, this tapered portion 52e is used for being led through filter element 2 from the 52a side direction cardinal extremity 52b side, top of wall portion 52, tapered portion 52e has inclined-plane S, this inclined-plane S is less by the overhang of the 52a side, top of wall portion 52, and the overhang by cardinal extremity 52b side is larger.This inclined-plane S can be utilized to be led through filter element 2 swimmingly.

And, the jut 52d of present embodiment along wall portion 52 circumference with the empty standard width of a room in an old-style house every mode be configured with multiple.When only there being a place jut 52d, also filter element 2 can be led through.But, when with place's jut 52d aligned position, filter cell 2, easily misplace with the contrary side of the part that jut 52d contacts.And, if to arrange premised on multiple jut 52d, then the jut 52d of the quantity of the shape being suitable for blood processing filter 1 can be configured.

And the jut 52d of present embodiment is along the circumference of wall portion 52 to configure at equal intervals, and its result, can be led through filter element 2 evenly, thus effectively can prevent dislocation.And, there are two groups of jut 52d be oppositely disposed across filter cell 2, therefore, it is possible to utilize each jut 52d group to clamp filter cell 2, thus can effectively prevent filter cell 2 from misplacing.In addition, with regard to preventing filter cell 2 from misplacing with regard to this effect, just can play this effect by being oppositely disposed at least one group of jut 52d, certainly, group number is more, more not easily misplaces.

And, the entrance side container member 4 of the blood processing filter 1 of present embodiment and outlet side container member 5 have the fitting portion 7 be fitted together in the mode be surrounded by the end face 2c of filter cell 2, therefore, it is possible to easily entrance side container member 4 is aimed at outlet side container member 5 and they is joined together.

And, the resin 6 that is melted at least partially that the fitting portion 7 of present embodiment has the entrance side fitting portion 4d being located at entrance side container member 4 and the outlet side fitting portion 5d being located at outlet side container member 5, the sliding contacting part 7a between entrance side fitting portion 4d and outlet side fitting portion 5d is zonally be bonded together on the complete cycle of fitting portion 7.Its result, by being melted resin 6 in being zonally bonded together on the complete cycle of fitting portion 7, thus can improve air-tightness and fluid tight.

And, resin stream 8 is provided with at the sliding contacting part 7a of present embodiment, by molten resin 6 being filled in resin stream 8, sliding contacting part 7a is bonded together, therefore, molten resin 6 not easily overflows from sliding contacting part 7a, thus can reduce molten resin 6 and enter probability in container.

And jut 52d also has fixed part 52f, this fixed part 52f can with the end face 2c close contact of filter cell 2 thus supporting filter device element 2.Suppose not arrange fixed part 52f, then need to be born by tapered portion 52e to be led through filter element 2 and these two functions of Fixed-Filter element 2, and be difficult to the optimization realizing angle of inclination δ.But, if tapered portion 52e and fixed part 52f can be arranged at jut 52d, then can realize as under type, that is, to tapered portion 52e, the tilt angle theta easily allowing filter cell 2 be configured in assigned position is made it have, conversely, to fixed part 52f, preferentially make filter cell 2 after filling, be in the state not easily misplaced, thus easily can realize the optimization of blood processing filter 1.

Above-mentioned effect, effect are not limited to the blood processing filter 1 of present embodiment, and blood processing filter 1A, 1B, 1C, 1D, 1E, 1F, the 1G of such as, each embodiment shown in Fig. 7 (a) ~ Fig. 7 (d) or Fig. 8 (a) ~ Fig. 8 (d) also can play above-mentioned effect, effect.

First, Fig. 7 (a) is the top view of the overview of the blood processing filter 1A representing the 2nd embodiment, Fig. 7 (b) is the top view of the overview of the blood processing filter 1B representing the 3rd embodiment, Fig. 7 (c) is the top view of the overview of the blood processing filter 1C representing the 4th embodiment, and Fig. 7 (d) is the top view of the overview of the blood processing filter 1D representing the 5th embodiment.

Such as also as the blood processing filter 1A of the 2nd embodiment (with reference to Fig. 7 (a)), compared to the blood processing filter 1 of the 1st embodiment, the width of each jut 53d can be widened.And, if as the blood processing filter 1B (with reference to Fig. 7 (b)) of the 3rd embodiment, the words that two place jut 54d amount to configuration 4 place jut 54d are respectively configured in diagonal angle part, then filter cell can be aligned in appropriate location, thus the situation of dislocation occurs after more effectively can suppressing that filter cell is imported container.In addition, the jut 54d of present embodiment observes in alphabetical L shape from depression angle, and its bight along filter cell 2 bends, therefore, it is possible to aligned position more rightly.But, also can not bend, such as, also can be, jut same for the jut 53d of the blood processing filter 1A of the jut 52d of the blood processing filter 1 with the 1st embodiment or the 2nd embodiment is arranged near each bight.And, in the present embodiment, although be illustrated for tetragonal blood processing filter 1B, also can be applied in the polygonal blood processing filter of rhombus or pentagon and more polygon number.

And, also can as the blood processing filter 1C of the 4th embodiment (with reference to Fig. 7 (c)), being seated in by the filter cell 2 of circle observes rounded blood processing filter 1C from depression angle, in this embodiment, many places (such as 3 places) in the circumference of filter cell 2 are provided with jut 55d, are particularly disposed at equal intervals jut 55d.When the circumference in this wise along circular filter cell 2 configures jut 55d in the position being more than equally spaced 3 places, easily by filter cell 2 aligned position, be therefore preferred.

And, when as the blood processing filter 1D (with reference to Fig. 7 (d)) of the 5th embodiment, two place jut 56d are configured when amounting to configuration 8 place jut 56d on each limit of the blood processing filter 1D of rectangle, filter cell 2 is easily subject to the guiding from each bar limit of rigid container 3 equably, thus can, more easily by filter cell 2 aligned position, therefore be preferred.

And, Fig. 8 (a) for comparing with other embodiments, the sectional view of the wall portion 52 of the blood processing filter 1 of the 1st embodiment, Fig. 8 (b) is the sectional view of the wall portion 52E of the blood processing filter 1E of the 6th embodiment, Fig. 8 (c) is the sectional view of the wall portion 52F of the blood processing filter 1F of the 7th embodiment, and Fig. 8 (d) is the sectional view of the wall portion 52G of the blood processing filter 1G of the 8th embodiment.

Part by the opposite face 52c side local of the top 52a of the wall portion 52 (with reference to Fig. 8 (a)) of the 1st embodiment is cut off and defines rake 52g, the tapered portion 52e of this rake 52g and jut 52d at grade (continuously) couple together.And, wall portion 52, be provided with fixed part 52f than tapered portion 52e by the part of cardinal extremity 52b side.The quantity of the inclined-plane S of tapered portion 52e is one, and thus tilt angle theta is one.

On the other hand, as shown in Fig. 8 (b), in the blood processing filter 1E of the 6th embodiment, the tapered portion 57e bending of jut 57d, thus there are two inclined-planes S1, S2.And the tilt angle theta by the inclined-plane S1 of the 52a side, top of wall portion 52E is greater than the tilt angle theta of the inclined-plane S2 by cardinal extremity 52b side.And, as shown in Fig. 8 (c), in the blood processing filter 1F of the 7th embodiment, the tapered portion 58e bending of jut 58d, thus there are three inclined-planes S3, S4, S5, tilt angle theta near the 1st inclined-plane S3 of the top 52a of wall portion 52F is maximum, and secondly the tilt angle theta of the 2nd inclined-plane S4 of the top 52a of close wall portion 52F is less than the tilt angle theta of the 1st inclined-plane S3, but is greater than the tilt angle theta of the 3rd inclined-plane S5 near cardinal extremity 52b.In addition, same with the blood processing filter 1 of the 1st embodiment, part by the opposite face 52c side local of the top 52a of the wall portion 52E of the 6th embodiment and the wall portion 52F of the 7th embodiment is cut off and defines rake 52g, this rake 52g and tapered portion 57e, 58e at grade (continuously) couple together.

And, as shown in Fig. 8 (d), in the blood processing filter 1G of the 8th embodiment, it is continuous sleekly that tapered portion 52p is curved (convex-shaped), the angle of inclination of tapered portion 52p refers to that this tangent line is relative to the angle of opposite face 52c when supposing the tangent line of curved surface.And in the tapered portion 52p of the blood processing filter 1G of the 8th embodiment, the angle of inclination by the 52a side, top of wall portion 52G is greater than the angle of inclination by cardinal extremity 52b side.In addition, the wall portion 52G of the 8th embodiment is formed with curved rake 52n at top 52a, and this rake 52n and curved tapered portion 52p (continuously) on same curved surface couples together.

By as the blood processing filter 1E of the 6th embodiment and the blood processing filter 1F of the 7th embodiment, make tapered portion 57e, 58e has multiple inclined-plane S1 ~ S5, such as when yielding filter cell 2 is seated in rigid container 3, also filter cell 2 can be guided to the direction that will locate at leisure, and excessive load can not be applied to filter cell 2.In addition, multiple inclined-plane S1 ~ S5 both can get up bendingly continuously, also can as the blood processing filter 1G of the 8th embodiment, and get up continuously sleekly in curved, which also can play same effect.In addition, due to sometimes also may along with technical difficulty during Mold Making curved surface, therefore, consider from manufacture view, continuous print mode be favourable bendingly sometimes.

Then, an example of the manufacture method of blood processing filter 1,1A ~ 1G is described.In addition, only there is for tapered portion 52e the blood processing filter 1 of an inclined-plane S below, its manufacture method is described, but for the blood processing filter 1A ~ 1G of other embodiments, consist essentially of same operation.First, the injection (mo(u)lding) machine 10 that this manufacture method uses is described.

As shown in Figure 10, injection (mo(u)lding) machine 10 comprises fixed die 11, But moving die (mould) 12 and the mobile mould (mould) 13 that slides.Fixed die 11 is fixed on the fixed disk (not shown) of injection (mo(u)lding) machine 10.Be provided with pallet 15 at the upper surface of this fixed die 11, pallet 15 has the cylinder 14 of slip.And the cylinder 14 utilizing hydraulic pressure or air pressure etc. to carry out work is attached at the upper surface of the mobile mould 13 that slides.And the mobile mould 13 that slides can keep sliding up and down with the state of the side surface close contact of fixed die 11 movement.

On movable plate (not shown) that But moving die 12 is arranged on injection (mo(u)lding) machine 10, that can freely move horizontally.This movable plate can utilize the die sinking mold closing mechanism (not shown) of injection (mo(u)lding) machine 10 to move to close or away from fixed die 11 direction.Thus, But moving die 12 can move between die-closed position and die sinking position, die-closed position refer to slide mobile mould 13 close contact time position, die sinking position refers to and leaves the position after mobile mould 13 of sliding.

Be provided with running channel 11a in the center of fixed die 11, this running channel 11a is used for guiding the molten resin 16 of coming in from injector (not shown) injection, and wherein injector is installed on fixed die 11.And, central secondary running channel 13a and the secondary running channel 13b in below is provided with at the mobile mould 13 of slip, the secondary running channel 13a of central authorities is connected with running channel 11a when the mobile mould 13 that slides is positioned at lower position, and the secondary running channel 13b in below is connected with running channel 11a when the mobile mould 13 that slides moves to top position.

And, slide mobile mould 13 land area, with central authorities secondary running channel 13a for the symmetric position that symmetrical centre is upper and lower is provided with formpiston 13c and former 13d.This formpiston 13c is for the inner surface of the entrance side container member 4 that is shaped, and former 13d is used for the outer surface of contoured exit side container member 5.On the other hand, be provided with former 12c and formpiston 12d at the land area of But moving die 12, when the mobile mould 13 that slides is positioned at lower position, former 12c is relative with formpiston 13c, and formpiston 12d is relative with former 13d.This former 12c is for the outer surface of the entrance side container member 4 that is shaped, and formpiston 12d is used for the inner surface of contoured exit side container member 5.And as is illustrated by figs. 11 and 12, when the mobile mould 13 that slides is positioned at top position, the former 12c of this But moving die 12 side is relative with the former 13d of mobile mould 13 side of sliding.

And, as shown in Figure 10, when the mobile mould 13 that slides be positioned at lower position and But moving die 12 with slide mobile mould 13 matched moulds time, between the mobile mould 13 of this slip and But moving die 12, be formed with a pair space 17,18 be surrounded by formpiston 13c and former 12c, formpiston 12d and former 13d respectively.Now, these spaces are connected with the secondary running channel 13a of the central authorities of the mobile mould 13 that slides via the runner 12e be formed on But moving die 12 and a pair cast gate 12f from the end edge portion of each former 13d, 12c.And, as shown in figure 12, when the mobile mould 13 that slides be positioned at top position and But moving die 12 with slide mobile mould 13 matched moulds time, the former 13d of the mobile mould 13 of this slip docks mutually with the former 12c of But moving die 12, and the end edge portion of these formers 13d, 12c is connected with runner 12e with the secondary running channel 13b in below via cast gate 12f.

Utilize injection (mo(u)lding) machine 10 be shaped blood processing filter 1 time, first, as shown in Figure 10, cylinder 14 is extended and then makes the mobile mould 13 of slip be positioned at lower position.Then, the movable plate of injection (mo(u)lding) machine 10 is moved to fixed disk side, by mobile for slip mould 13 and But moving die 12 matched moulds.In this condition, the secondary running channel 13a of central authorities of the mobile mould 13 that slides is connected with the running channel 11a of fixed die 11, between the mobile mould 13 of slip and But moving die 12, be formed with a pair space 17,18.

Then, from the injector injecting molten resin 16 being installed on fixed disk, and molten resin 16 is directed in two spaces 17,18 via the secondary running channel 13a of central authorities, the runner 12e and cast gate 12f of the running channel 11a of fixed die 11, the mobile mould 13 that slides, and then molten resin 16 is filled in these spaces 17,18.Like this, a pair entrance side container member 4 in male-female relationship and outlet side container member 5 (container member forming process) can be formed in each space 17,18.

To in a pair entrance side container member 4 of male-female relationship and outlet side container member 5 carry out cooling curing, afterwards, as shown in figure 11, utilize die sinking mold closing mechanism to make them be separated with slip mobile mould 13 die sinking But moving die 12.So each formpiston 13c, 12d leave this entrance side container member 4 and outlet side container member 5, entrance side container member 4 and outlet side container member 5 stay former 12c, 13d side respectively.When die sinking, the resin portion that have cured in the running channel 11a of mould, secondary running channel 13a, runner 12e and cast gate 12f etc. is outstanding and drop from mould.The entrance side container member 4 of such acquisition and outlet side container member 5 are provided with entrance side fitting portion 4d and outlet side fitting portion 5d, entrance side fitting portion 4d and outlet side fitting portion 5d and mutually dock along the inner edge of its rectangular profile and form fitting portion 7.

Then, implement filling operation, the filter cell 2 comprising polyester non-woven fabric is seated in outlet side container member 5 inner.At this, being provided with the wall portion 52 that the end face 2c of filter cell 2 can be surrounded at outlet side container member 5, being provided with for being led through the jut 52d of filter element 2 to the installation of internal tank in wall portion 52.Thus, when implementing filling operation, filter cell 2 is guided to the assigned position of outlet side container member 5 inside by jut 52d, and thus, filter cell 2 also not easily misplaces in aftermentioned operation.Its result, easily can realize filter cell 2 and be built in the blood processing filter 1 of rigid container 3 inside validly, therefore, it is possible to the risk that when easily avoiding using, bad composition is removed insufficient.

Then, cylinder 14 is shunk, make the mobile mould 13 of slip move to top position.So the former 13d of the mobile mould 13 that slides is relative with the former 12c of But moving die 12, stay entrance side container member 4 in these formers 13d, 12c and outlet side container member 5 in state respect to one another.Now, the secondary running channel 13b in below of mobile mould 13 of sliding is positioned at the position be connected with the running channel 11a of fixed die 11.Make in this condition But moving die 12 to slip mobile mould 13 side move, as shown in figure 12, by their docking get up so that by their matched moulds (bonding process).That is, perform below such bonding process: under the state being filled with filter cell 2, entrance side container member 4 is docked with outlet side container member 5, simultaneously outer edge 2d, 2e of compression filter element 2.Now, the groove 4b of sliding contacting part 7a and groove 5b defines the resin stream 8 of empty shape.

In addition, in the above-mentioned bonding process of present embodiment, by mobile for slip mould 13 and But moving die 12 matched moulds, and then under the state across filter cell 2, make entrance side container member 4 and outlet side container member 5 tabling, therefore, easily entrance side container member 4 can be aimed at outlet side container member 5, thus can more reliably they be joined together.

The resin stream 8 formed in bonding process has through hole, and resin stream 8 is connected with cast gate 12f by through hole, and cast gate 12f is connected with secondary running channel 13b by runner 12e again.In this condition, from injector injecting molten resin 16, as the molten resin 6 (with reference to Fig. 3) for being filled in resin stream 8.So this molten resin 16, via the running channel 11a of fixed die 11, secondary running channel 13b, runner 12e, cast gate 12f and through hole, is filled in resin stream 8 by as molten resin 6.Thus, the periphery of the fitting portion 7 of entrance side container member 4 and outlet side container member 5 is melted resin 6 each other and is bonded together (affixed operation).Utilize the maneuver of filling molten resin 6 in this wise after forming resin stream 8, easily control amount of resin.

After cooling curing is carried out to this molten resin 6, again utilize die sinking mold closing mechanism by mobile for slip mould 13 and But moving die 12 die sinking, now, entrance side container member 4 is with outlet side container member 5 tabling and be joined together, thus can obtain the blood processing filter 1 made as complete seal molding product.And the resin portion that have cured in running channel 11a, secondary running channel 13b, runner 12e and cast gate 12f etc. is outstanding and drop from mould.

After being unloaded down by the blood processing filter made through above-mentioned operation 1, again make cylinder 14 extend, make the mobile mould 13 of slip be positioned at lower position.Then, by But moving die 12 and mobile mould 13 matched moulds that slides, the forming process of next product is transferred to.Then, repeat above-mentioned such a series of operation, thus the blood processing filter 1 that can be shaped continuously.And this forming process comprises makes that the mobile mould of slip 13 slides up and down, injecting molten resin 16, to be moved forward and backward carry out matched moulds and the such simple procedures of die sinking by But moving die 12, therefore, the automatization of above-mentioned all process steps also easily can be realized.Thus, blood processing filter 1 can be produced in batches.

By means of only utilizing one group of mould and But moving die 12 and slide mobile mould 13 and injection (mo(u)lding) machine 10 as described above, just can be carried out continuously being seated in from injection moulding entrance side container member 4 and outlet side container member 5, by filter cell 2 in container member by single operation, this series of process to the container member in male-female relationship and entrance side container member 4 and outlet side container member 5 are joined together, for complete hermetic product, also can form.

Above, with regard to the blood processing filter 1 of each embodiment, 1A ~ 1G, filter cell 2 is being seated in the operation in the outlet side container member 5 being provided with wall portion 52,52E ~ 52G, filter cell 2 is guided to the assigned position of container member inside by jut 52d, 53d, 54d, 55d, 56d, 57d, 58d, 59d, and therefore filter cell 2 not easily misplaces.Its result, easily can realize filter cell 2 and be built in the blood processing filter 1 of rigid container 3 inside validly, therefore, it is possible to the risk that when easily avoiding using, bad composition is removed insufficient.

In addition, in the respective embodiments described above, to wall portion 52,52E ~ 52G being located at outlet side container member 5 and mode filter cell 2 being seated in outlet side container member 5 inside is illustrated in detail, but for the wall portion being provided with jut being located at entrance side container member 4 and filter cell 2 being seated in the mode of entrance side container member 4 inside, in fact also same functions and effects can be played.

And, adopt the manufacture method of above-mentioned embodiment, can easily and efficiently manufacture blood processing filter 1,1A ~ 1G, therefore highly beneficial at manufacture view.And, for manufacture method in the past, when the problem etc. misplaced because of filter cell or fall and cause equipment to stop, production efficiency can be caused to reduce, but, according to the manufacture method of above-mentioned blood processing filter 1,1A ~ 1G, then can avoid the problems referred to above.

Above, with reference to embodiment, this utility model is illustrated, but this utility model is not limited to above-mentioned embodiment.Also can be such as utilize high-frequency welding to weld in the lump between rigid container 3 and filter cell 2 thus to obtain blood processing filter 1 after entrance side container member 4 is chimeric with outlet side container member 5.Moreover, it can be, after formation rigid container 3, by other means molten resin 6 to be filled in resin stream 8 thus to obtain blood processing filter 1.These other modes such as can list following manner: filling filter cell 2, and in advance molten resin 6 is filled in the groove 4b or groove 5b forming resin stream 8 at least in any one, then carry out matched moulds.

And, in the blood processing filter 1 of present embodiment, the mode being provided with fitting portion 7 is illustrated, but also can be, not arranging fitting portion 7, such as, also can be the structure with the in one plane such entrance side junction surface (not shown) of sliding contacting part 7a and outlet side junction surface (not shown).That is, entrance side container member 4 and outlet side container member 5 also can not form male-female relationship.

Claims (15)

1. a blood processing filter, it, for removing bad composition from comprising in the liquid of blood constituent or blood, is characterized in that,

This blood processing filter comprises:

The filter cell of lamellar; And

Container, it has entrance side container member and outlet side container member, and across above-mentioned filter cell between entrance side container member and outlet side container member, interior of the container is separated into entrance space and outlet space by above-mentioned filter cell,

Above-mentioned filter cell has: a pair filtering surface, and they are configured in above-mentioned entrance space side and above-mentioned outlet space side respectively; And end face, it is along the periphery of above-mentioned a pair filtering surface,

Be provided with handle part at above-mentioned entrance side container member and above-mentioned outlet side container member, this handle part is used for the clamping of the outer edge of above-mentioned a pair filtering surface get up and compress,

At least one in above-mentioned entrance side container member and above-mentioned outlet side container member is provided with wall portion, and the above-mentioned end face of above-mentioned filter cell is surrounded by this wall portion,

Above-mentioned wall portion has: opposite face, and it is relative with above-mentioned end face; And jut, it is given prominence to from above-mentioned opposite face, for guiding above-mentioned filter cell to the installation of internal tank.

2. blood processing filter according to claim 1, is characterized in that,

Above-mentioned jut has tapered portion, and this tapered portion is used for guiding above-mentioned filter cell from the tip side of above-mentioned wall portion to base end side,

Above-mentioned tapered portion has inclined-plane, and the overhang of the above-mentioned tip side by above-mentioned wall portion on this inclined-plane is less, and the overhang by above-mentioned base end side is larger.

3. blood processing filter according to claim 2, is characterized in that,

The angle of inclination on above-mentioned inclined-plane is less than 60 ° with the above-mentioned opposite face of above-mentioned wall portion for benchmark.

4. blood processing filter according to claim 3, is characterized in that,

Above-mentioned tapered portion has multiple inclined-plane, and the angle of inclination by the above-mentioned inclined-plane of the above-mentioned tip side of above-mentioned wall portion is greater than the angle of inclination on the above-mentioned inclined-plane by above-mentioned base end side.

5. the blood processing filter according to any one of claim 2 ~ 4, is characterized in that,

Above-mentioned jut has fixed part, the above-mentioned end face close contact of this fixed part and above-mentioned filter cell thus support above-mentioned filter cell, and fixation portions is formed in than the position of above-mentioned tapered portion by the above-mentioned base end side of above-mentioned wall portion.

6. blood processing filter according to claim 5, is characterized in that,

Fixation portions has the angle of inclination at the angle of inclination being less than above-mentioned tapered portion, and the angle of inclination of fixation portions is less than 10 °.

7. blood processing filter according to claim 6, is characterized in that,

The gross area that fixation portions contacts with the end face of above-mentioned filter cell is less than 5% of the gross area of the above-mentioned end face of above-mentioned filter cell.

8. blood processing filter according to claim 7, is characterized in that,

The summation of the width that fixation portions contacts with the end face of above-mentioned filter cell is less than 15% of the periphery length of above-mentioned filter cell.

9. the blood processing filter according to any one of Claims 1 to 4, is characterized in that,

Above-mentioned jut along above-mentioned wall portion circumference with the empty standard width of a room in an old-style house every mode be configured with multiple.

10. blood processing filter according to claim 9, is characterized in that,

Above-mentioned multiple jut along the circumference of above-mentioned wall portion to configure at equal intervals.

11. blood processing filters according to claim 10, is characterized in that,

At least one group of jut in above-mentioned multiple jut is oppositely disposed across above-mentioned filter cell.

12. blood processing filters according to any one of Claims 1 to 4, is characterized in that,

Above-mentioned entrance side container member and above-mentioned outlet side container member also have fitting portion, and this fitting portion is fitted together in the mode be surrounded by the above-mentioned end face of above-mentioned filter cell,

Above-mentioned fitting portion has above-mentioned wall portion.

13. blood processing filters according to claim 12, is characterized in that,

Above-mentioned fitting portion has the entrance side fitting portion being located at above-mentioned entrance side container member and the outlet side fitting portion being located at above-mentioned outlet side container member, and the resin that is melted at least partially of the sliding contacting part between above-mentioned entrance side fitting portion and above-mentioned outlet side fitting portion is zonally be bonded together on the complete cycle of above-mentioned fitting portion.

14. blood processing filters according to claim 13, is characterized in that,

Be provided with resin stream at above-mentioned sliding contacting part, by above-mentioned molten resin is filled in above-mentioned resin stream, above-mentioned sliding contacting part be bonded together.

15. blood processing filters according to any one of Claims 1 to 4, is characterized in that,

Said vesse is that the resin being more than 0.1GPa by the Young's modulus under room temperature is made.