CN204958920U - Stem cell transfer device - Google Patents

Stem cell transfer device Download PDF

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Publication number
CN204958920U
CN204958920U CN201520739736.0U CN201520739736U CN204958920U CN 204958920 U CN204958920 U CN 204958920U CN 201520739736 U CN201520739736 U CN 201520739736U CN 204958920 U CN204958920 U CN 204958920U
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China
Prior art keywords
bottle
stem cell
cell transfer
transfer device
liquid outlet
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CN201520739736.0U
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Chinese (zh)
Inventor
张晓南
吴芳春
刘显云
邵来
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Beijing Yulong Shengshi Biotechnology Co Ltd
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Beijing Yulong Shengshi Biotechnology Co Ltd
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Abstract

The utility model provides a stem cell transfer device, including shifting the bottle, shift the bottle at least including the bottle, the flexible inner membrance of inner wall laminating of bottle, the bottleneck punishment of bottle do not is equipped with annotates liquid mouth and liquid outlet, be equipped with sealed lid on the notes liquid mouth, the liquid outlet is connected with the transfusion system, it is equipped with the protection enclosing cover still to cover on the bottleneck of bottle. The utility model discloses a stem cell transfer device, simple structure, convenient to use are equipped with the duroplasts protective housing, the difficult condition that damage and weeping appear, elasticity is intimal to set up effective phenomenon that reduces the stem cell wall built -up, avoids the waste in the stem cell transfer process, it separately sets up to annotate liquid mouth and liquid outlet to and the setting of sealed lid and seal cover, fundamentally has solved the pollution problem in the stem cell transfer process.

Description

A kind of stem cell transfer device
Technical field
The utility model relates to biological technique with the apparatus field, particularly relates to a kind of stem cell transfer device.
Background technology
Stem cell (stemcells, SC) is the multipotential cell that a class has the of self-replication capacity (self-renewing), and under certain condition, it can be divided into several functions cell.Stem cell is the initiating cell with self-replacation and multi-lineage potential, is the cells of origin of body, is the initiating cell forming the various histoorgan of human body.Under certain condition, it can be divided into several functions cell or tissue organ, and medical circle is called " general-purpose cell ".Stem-cell therapy is the stem cell transplantation of health in patient or oneself body, to reach the object of repairing sick cell or the normal biological cells and tissues of Reconstruction of The Function.Stem cell therapy injects new vitality just as to body, is the effective ways of fundamentally treating numerous disease.
In theory, application of stem cells technology can treat the various diseases of the multiple systems such as neural system, the recycle system, and more a lot of traditional therapy has unrivaled advantage: safety, hypotoxicity (or nontoxicity); Also can apply some symptom before the exact mechanism understanding disease incidence not yet completely, stem cell transplantation successful, disposable implantation, persistent; Graft materials source is sufficient; Best immunotherapy and gene therapy vector; Therapeutic domain is wide, can treat most of disease in theory; To take new therapy and new hope to the disease being considered to " incurable disease " under those traditional remedies.
Authorization Notice No. is in the license file of CN202136635U, discloses a kind of transfusion bag for stem cell injection, comprises bag, bag interface, infusion tube, infusion tube interface, syringe needle.Wherein infusion tube is connected with the bag interface on bag by infusion tube interface, and bag interface and infusion tube interface are movable connection.Bag is made up of medical transparent material, bag mark scale.Bag one end has a hanging hole, and the other end is bag interface, and bag interface position comparatively bag itself is hard, and bag interface and infusion tube interface adopt buckle to be connected or knob connects.It is a sealing membrane that bag interface is positioned at bag interior surface.
Above-mentioned stem cell transfer device is the transfering bag of flexible plastic material, and this kind of device, in the process of transfer stem cell, exists the phenomenons such as cracky, easily wall built-up, leakage, cell settlement, causes pollution and the waste of stem cell.
Therefore, the stem cell transfer device how inventing a kind of not cracky, not easy-to-leak liquid, not easily wall built-up is that those skilled in the art have technical barrier to be solved.
Utility model content
The utility model technical problem provided as solving provides a kind of stem cell transfer device, structure is simple, easy to use, not easily there is situation that is damaged and leakage, effectively reduce the phenomenon of stem cell wall built-up, and then the problem of the pollution fundamentally avoided in stem cell transfer process and waste.
For solving the problems of the technologies described above, the utility model comprises following technical scheme:
A kind of stem cell transfer device; comprise transfer bottle; described transfer bottle at least comprises bottle; the inwall of described bottle is fitted with elastic inner membrane; the bottle mouth position of described bottle is respectively equipped with spout and liquid outlet; described spout is provided with sealing cover, and described liquid outlet is connected with transfusion device, and the bottleneck of described bottle is also covered with protection enclosing cover.
Stem cell transfer device of the present utility model, the multilayer protection of elastic inner membrane, bottle and protection enclosing cover effectively reduces the situation of breakage, leakage and wall built-up; Spout and liquid outlet are provided separately, and the setting of sealing cover and seal cartridge, solve the pollution problem in stem cell transfer process; When shifting bottle built with cell solution, elastic inner membrane expands and produces inside pressure, cell solution is forced to export, after cell solution has exported, elastic inner membrane shortens original size into, because the relative surface area of elastic inner membrane is far smaller than bag of saline or the transfering bag of same volume, so the quantity that elastic inner membrane upper wall remains stem cell is also the quantity being far smaller than residual stem cell on the bag of saline of same volume or transfering bag.
As preferably, described spout comprises from bottom to top: the diversion section of expanding entrance and isometrical extension; Described entrance is positioned at the outside of described bottle, and described diversion section stretches into the inside of described bottle, and described entrance and diversion section are structure as a whole.Expanding entrance, can not trickle down easily, facilitate fluid injection, and diversion section stretches to the position close to bottle body bottom always, prevents the splashing of cell solution in injection process.
As preferably, the bottle mouth position of described bottle extends shirt rim along sidewall, and described spout and liquid outlet are all positioned at the inboard of described shirt rim.Protection spout and liquid outlet effect can be played in shirt rim, all right preventing pollution further, and bottle passes through the outside of shirt rim and protection enclosing cover thread fit in addition.
For convenience of being fixed stem cell transfer device, as preferably, be provided with link at the bottom of the bottle of described transfer bottle, described link is connected with retaining clip.
As preferably, described transfusion device at least comprises tubing, and one end of described tubing is connected with described liquid outlet, and the other end of tubing is connected with infusion port, and described tubing is also provided with flow regulator and liquid-stopping device.In stem cell transfer process, the flow velocity of cell solution can be regulated arbitrarily by flow regulator, control the carrying out of cell solution transfer at any time by liquid-stopping device and stop.
For protection infusion port is not contaminated, as preferably, prevent cell solution contaminated for protection infusion port, as preferably, on described infusion port, thread fit has seal cartridge.
As preferably, described protection enclosing cover, by shirt rim and described bottle thread fit, covers the through hole be also provided with for by described tubing outside described protection.
Further preferably, the skin of described bottle and protection enclosing cover is also provided with duroplasts protective shell.Rigid plastics is not easy impaired, effectively can prevent leakage.
The beneficial effects of the utility model are as follows:
Stem cell transfer device of the present utility model, structure is simple, easy to use, adopts bottle and the protection enclosing cover of mechanically resistant material, not easily occurs situation that is damaged and leakage; The setting of elastic inner membrane effectively reduces the phenomenon of stem cell wall built-up, avoids the waste in stem cell transfer process; Spout and liquid outlet are provided separately, and the setting of sealing cover and seal cartridge, fundamentally solve the pollution problem in stem cell transfer process.
Accompanying drawing explanation
Fig. 1 is the structural representation of the utility model stem cell transfer device.
Embodiment
For enabling above-mentioned purpose of the present utility model, feature and advantage become apparent more, are described in detail embodiment of the present utility model below in conjunction with accompanying drawing.
Fig. 1 is the structural representation of stem cell transfer device in the utility model embodiment.
As shown in Figure 1; the stem cell transfer device of the present embodiment comprises transfer bottle 1, wherein shifts bottle 1 and comprises bottle 10, fit in the elastic inner membrane 20 of bottle 10 inwall; cover at the protection enclosing cover 30 on the bottleneck of bottle 10, and be located at the link 40 at the bottom of bottle of bottle 10.The skin of bottle 10 and protection enclosing cover 30 is also provided with duroplasts protective shell, and rigid plastics is not easy impaired, effectively can prevent leakage.
The bottle mouth position of bottle 10 extends shirt rim 13 along sidewall, and the bottle mouth position of bottle 10 is respectively equipped with spout 11 and liquid outlet 12, and wherein spout 11 and liquid outlet 12 are all positioned at the inboard of shirt rim 13.Protection spout 11 can be played in shirt rim 13 and liquid outlet 12 acts on, and can also prevent bottle mouth position from being polluted, spout 11 and liquid outlet 12 are provided separately, and solve the pollution problem in stem cell transfer process further.
Spout 11 comprises from bottom to top: expanding entrance 111 and the diversion section 112 of isometrical extension.Entrance 111 is positioned at the outside of bottle 10, and diversion section 112 stretches into the inside of bottle 10, and entrance 111 and diversion section 112 are structure as a whole, and spout 11 is also provided with sealing cover 113, covers spout 11 in case leak-stopping liquid after fluid injection completes with sealing cover 113.Expanding entrance 111, when can prevent fluid injection, cell solution is unrestrained, and facilitate fluid injection, diversion section 112 stretches to the position bottom close to bottle 10 always, prevents the splashing of cell solution in injection process.
Liquid outlet 12 is connected with transfusion device 2.Transfusion device 2 comprises tubing 21, and one end of tubing 21 is connected with liquid outlet 12, and the other end of tubing 21 is connected with infusion port 211, and on infusion port 211, thread fit has seal cartridge 214, tubing 21 is also provided with flow regulator 212 and liquid-stopping device 213.In stem cell transfer process, the flow velocity of cell solution can be regulated arbitrarily by flow regulator 212, control the carrying out of cell solution transfer at any time by liquid-stopping device 213 and stop.
Elastic inner membrane 20 fits in bottle 10 inwall, when shifting bottle 1 built with cell solution, elastic inner membrane 20 expands and produces inside pressure, cell solution is forced to export, after cell solution has exported, elastic inner membrane 20 shortens original size into, because the relative surface area of elastic inner membrane 20 is far smaller than bag of saline or the transfering bag of same volume, so the quantity that elastic inner membrane 20 upper wall remains stem cell is also the quantity being far smaller than residual stem cell on the bag of saline of same volume or transfering bag, so the present embodiment efficiently solves the problem of easy wall built-up in prior art.
Protect enclosing cover 30 and pass through shirt rim 13 bottle 10 thread fit, protection enclosing cover 30 is also provided with for the through hole 31 by tubing 21.
Link 40 is connected with retaining clip 41, arranging of retaining clip 41 is conveniently fixed stem cell transfer device.
In sum, stem cell transfer device of the present utility model, structure is simple, easy to use, adopts bottle and the protection enclosing cover of mechanically resistant material, not easily occurs situation that is damaged and leakage; The setting of elastic inner membrane effectively reduces the phenomenon of stem cell wall built-up, avoids the waste in stem cell transfer process; Spout and liquid outlet are provided separately, and the setting of sealing cover and seal cartridge, fundamentally solve the pollution problem in stem cell transfer process.
The above embodiment is only that preferred implementation of the present utility model is described; not scope of the present utility model is limited; under the prerequisite not departing from the utility model design spirit; the various distortion that those of ordinary skill in the art make the technical solution of the utility model and improvement, all should fall in protection domain that claims of the present utility model determine.

Claims (8)

1. a stem cell transfer device; comprise transfer bottle (1); it is characterized in that; described transfer bottle (1) at least comprises bottle (10); the inwall of described bottle (10) is fitted with elastic inner membrane (20); the bottle mouth position of described bottle (10) is respectively equipped with spout (11) and liquid outlet (12); described spout (11) is provided with sealing cover (113); described liquid outlet (12) is connected with transfusion device (2), the bottleneck of described bottle (10) is also covered with protection enclosing cover (30).
2. stem cell transfer device as claimed in claim 1, it is characterized in that, described spout (11) comprises from bottom to top: expanding entrance (111) and the diversion section (112) of isometrical extension; Described entrance (111) is positioned at the outside of described bottle (10), described diversion section (112) stretches into the inside of described bottle (10), and described entrance (111) and diversion section (112) are structure as a whole.
3. stem cell transfer device as claimed in claim 1, it is characterized in that, the bottle mouth position of described bottle (10) extends shirt rim (13) along sidewall, and described spout (11) and liquid outlet (12) are all positioned at the inboard of described shirt rim (13).
4. stem cell transfer device as claimed in claim 1, it is characterized in that, be provided with link (40) at the bottom of the bottle of described transfer bottle (1), described link (40) is connected with retaining clip (41).
5. stem cell transfer device as claimed in claim 1, it is characterized in that, described transfusion device (2) at least comprises tubing (21), one end of described tubing (21) is connected with described liquid outlet (12), the other end of tubing (21) is connected with infusion port (211), described tubing (21) is also provided with flow regulator (212) and liquid-stopping device (213).
6. stem cell transfer device as claimed in claim 5, is characterized in that, the upper thread fit of described infusion port (211) has seal cartridge (214).
7. stem cell transfer device as claimed in claim 5; it is characterized in that; described protection enclosing cover (30), by shirt rim (13) and described bottle (10) thread fit, described protection enclosing cover (30) is also provided with the through hole (31) passed through for described tubing (21).
8. stem cell transfer device as claimed in claim 1, is characterized in that, the skin of described bottle (10) and protection enclosing cover (30) is also provided with duroplasts protective shell.
CN201520739736.0U 2015-09-22 2015-09-22 Stem cell transfer device Active CN204958920U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018023826A1 (en) * 2016-08-01 2018-02-08 北京臻惠康生物科技有限公司 Infusion pump and infusion method dedicated for stem cell
CN111433344A (en) * 2017-11-30 2020-07-17 康宁股份有限公司 Method and apparatus for aseptic dry transfer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018023826A1 (en) * 2016-08-01 2018-02-08 北京臻惠康生物科技有限公司 Infusion pump and infusion method dedicated for stem cell
CN107670145A (en) * 2016-08-01 2018-02-09 北京臻惠康生物科技有限公司 Infusion pump and infusion method special for stem cells
US11511036B2 (en) * 2016-08-01 2022-11-29 BENING ZHEN HUIKANG BIOLOGICAL TECH. Co., Ltd. Infusion pump and infusion method dedicated for stem cell
CN111433344A (en) * 2017-11-30 2020-07-17 康宁股份有限公司 Method and apparatus for aseptic dry transfer
US11655440B2 (en) 2017-11-30 2023-05-23 Corning Incorporated Methods and devices for aseptic dry transfer
CN111433344B (en) * 2017-11-30 2024-04-26 康宁股份有限公司 Method and apparatus for aseptic dry transfer

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