CN204881129U - Freeze -drying sheet layer interval adjustable freeze dryer - Google Patents

Freeze -drying sheet layer interval adjustable freeze dryer Download PDF

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Publication number
CN204881129U
CN204881129U CN201520491827.7U CN201520491827U CN204881129U CN 204881129 U CN204881129 U CN 204881129U CN 201520491827 U CN201520491827 U CN 201520491827U CN 204881129 U CN204881129 U CN 204881129U
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China
Prior art keywords
freeze
suspension rod
plate layer
drying plate
drying
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CN201520491827.7U
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Chinese (zh)
Inventor
许海兵
翁宽
阮凯
殷杰
袁志伟
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Truking Technology Ltd
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Truking Technology Ltd
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Abstract

The utility model discloses a freeze -drying sheet layer interval adjustable freeze dryer, including the freeze -drying chamber, the freeze -drying intracavity is equipped with the last extension board of liftable, the below of going up the extension board is equipped with N piece freeze -drying sheet layer, N piece freeze -drying sheet layer from last to lower sequentially numbered be 1, 2,. N, N >= 2, the correspondence of every freeze -drying sheet layer is equipped with the jib, each jib is all worn to locate go up on the extension board and can by go up the extension board and drive each freeze -drying sheet layer respectively and go up and down, number and be 2 jibs that correspond to N's freeze -drying sheet layer, be equipped with the restriction on the jib of the part or whole the locating part of distance between jib top and the last extension board. The utility model has the advantages of the structure is ingenious, economy is practiced thrift, freeze -drying sheet layer interval is adjustable.

Description

The freeze dryer that freeze-drying plate layer spacing is adjustable
Technical field
The utility model relates to freeze dryer, particularly relates to the freeze dryer that a kind of freeze-drying plate layer spacing is adjustable.
Background technology
The medicine bottle that freeze dryer is mainly used in having filled with medicine carries out freeze-drying operation, by the moisture evaporation in mixture in bottle, and completes the sealing of jumping a queue of bottle.Be provided with polylith in the freeze drying box of freeze dryer and be used for the freeze-drying plate layer of placing bottle body, polylith freeze-drying plate layer arranges from top to bottom, and every block freeze-drying plate layer can be elevated in freeze drying box.Spacing between adjacent two flaggies is identical, and therefore, a kind of freeze dryer of model, the flaggy spacing in its freeze drying box is fixing, and if flaggy spacing is 100mm, then this freeze dryer can only be of a size of the bottle of below 100mm by freeze-drying bottle.But in process of production, may produce differing heights medicine bottle, when needing freeze-drying, single plate gallery height cannot realize the freeze-drying of the medicine bottle with the relatively large discrepancy in elevation.And freeze dryer flaggy spacing is all fixing a certain height at present, the medicine bottle freeze-drying of differing heights is realized, then need separately to put a freeze dryer, consider all inadvisable from economy, benefit angle.
Utility model content
The technical problems to be solved in the utility model overcomes the deficiencies in the prior art, provides the freeze dryer that a kind of structure is simple, the freeze-drying plate layer spacing of economy, applicable different size bottle is adjustable.
For solving the problems of the technologies described above, the utility model by the following technical solutions:
The freeze dryer that a kind of freeze-drying plate layer spacing is adjustable, comprise freeze-drying chamber, liftable upper supporting plate is provided with in described freeze-drying chamber, the below of described upper supporting plate is provided with N block freeze-drying plate layer, described N block freeze-drying plate layer from top to bottom number consecutively is 1, 2, N, N >=2, every block freeze-drying plate layer correspondence is provided with suspension rod, each suspension rod to be all arranged on described upper supporting plate and each freeze-drying plate layer can be driven respectively to be elevated by described upper supporting plate, be numbered in suspension rod corresponding to the freeze-drying plate layer of 2 to N, part or all of suspension rod is provided with the locating part of the spacing of the described suspension rod top of restriction and upper supporting plate.
Further improvement as technique scheme:
Except being numbered 1,1+1M, 1+2M, 1+3M ..., 1+nM freeze-drying plate layer outside, the suspension rod corresponding to all the other freeze-drying plate layers is provided with the locating part of spacing of the described suspension rod top of restriction and upper supporting plate, and wherein, n is natural number, and M is the natural number of more than 2.
Described locating part is clip and alignment pin, described clip is provided with draw-in groove, the inwall of described draw-in groove is provided with installing hole, described alignment pin to be placed in described installing hole and to be connected with the inner thread of installing hole, described installing hole is stretched out in one end of the close draw-in groove of described alignment pin, and described suspension rod surface is provided with the locating hole with described detent fit.
Described draw-in groove is set to square, and described suspension rod is provided with the flat horizontal surface corresponding with described draw-in groove, and described locating hole is located on described flat horizontal surface.
Each suspension rod top is provided with block, and described locating part is between block and upper supporting plate and against described upper supporting plate, the locating part on each suspension rod is identical with the distance between block.
Every block freeze-drying plate layer edge is provided with hanger, and each suspension rod lower end is passed described hanger and is connected with an acorn nut.
The edge of described upper supporting plate is installed with boatswain chair, and described suspension rod is arranged in described boatswain chair, and described locating part is against described boatswain chair upper surface.
Described boatswain chair is set to four, is distributed in the both sides of upper supporting plate, and every side is provided with two, and each boatswain chair upper hanger quantity is identical with freeze-drying plate layer quantity.
N is 16, and the suspension rod quantity on each boatswain chair is 16, and 16 described suspension rods are evenly divided into two rows, and two suspension rod intervals that two adjacent freeze-drying plate layers are corresponding are arranged.
Compared with prior art, the utility model has the advantage of:
1, the freeze dryer that freeze-drying plate layer spacing of the present utility model is adjustable, each freeze-drying plate layer is to having suspension rod, except the suspension rod that first freeze-drying plate layer is corresponding, from the suspension rod that second freeze-drying plate layer is corresponding, the suspension rod that the freeze-drying plate layer of specific (part) is corresponding arranges the locating part limiting this length of boom, two pieces of freeze-drying plate layers of fitting and two pieces of freeze-drying plate layer gap-forming flaggy spacing of fitting are made by locating part, or the freeze-drying plate layer of three pieces of laminatings and three pieces of freeze-drying plate layer gap-forming flaggy spacing of fitting, change the spacing of freeze-drying plate layer thus, with by each block freeze-drying plate layer in prior art compared with one piece of freeze-drying plate layer gap-forming flaggy spacing, freeze-drying plate layer spacing increases, adjustable go out equally spaced freeze-drying plate layer spacing, compared with forming single constant flaggy spacing with freeze-drying plate layer in prior art 3, the utility model is by arranging locating part, be skillfully constructed, achieve freeze-drying plate layer spacing adjustable, be applicable to the bottle freeze-drying of larger number, expand the working range of freeze dryer, save cost,
2, the freeze dryer that freeze-drying plate layer spacing of the present utility model is adjustable, except the suspension rod that first freeze-drying plate layer is corresponding, the suspension rod corresponding at each freeze-drying plate layer is equipped with locating part, regulate the position of locating part on each suspension rod, the position between each freeze-drying plate layer can be regulated arbitrarily, form the flaggy spacing of different size, each flaggy spacing can be realized equal, also each flaggy spacing can be realized unequal mutually, same freeze dryer has the flaggy gap varied in size, multi-size, can place the bottle of different model simultaneously.
Accompanying drawing explanation
Fig. 1 is the structural representation of the first embodiment of the utility model.
Fig. 2 is the A place enlarged drawing of Fig. 1.
Fig. 3 is the top view of Fig. 1.
Fig. 4 is the B place enlarged drawing of Fig. 3.
Fig. 5 is the schematic diagram that each freeze-drying plate layer after adopting clip in the first embodiment of the utility model launches.
Fig. 6 is the structural representation of the clip of the first embodiment of the utility model.
Fig. 7 is the C-C view of Fig. 6.
Fig. 8 is the structural representation of the suspension rod of the first embodiment of the utility model.
Fig. 9 is the schematic diagram that after adopting clip in the utility model the second embodiment, each freeze-drying plate layer launches.
Figure 10 is the schematic diagram that in prior art, each freeze-drying plate layer launches.
In figure, each label represents:
1, freeze-drying chamber; 2, upper supporting plate; 3, freeze-drying plate layer; 4, suspension rod; 41, locating hole; 42, flat horizontal surface; 5, locating part; 51, clip; 511, draw-in groove; 512, installing hole; 52, alignment pin; 6, block a shot; 7, hanger; 8, acorn nut; 9, boatswain chair.
Detailed description of the invention
Below in conjunction with Figure of description and specific embodiment, the utility model is described in further detail.
Embodiment 1
As shown in Figures 1 to 8, the freeze dryer that freeze-drying plate layer spacing of the present utility model is adjustable comprises freeze-drying chamber 1, liftable upper supporting plate 2 is provided with in freeze-drying chamber 1, the below of upper supporting plate 2 is provided with N block freeze-drying plate layer 3, N block freeze-drying plate layer 3 from top to bottom number consecutively is 1, 2, N, N >=2, every block freeze-drying plate layer 3 correspondence is provided with suspension rod 4, each suspension rod 4 to be all arranged on upper supporting plate 2 and each freeze-drying plate layer 3 can be driven respectively to be elevated by upper supporting plate 2, be numbered in the suspension rod 4 of freeze-drying plate layer 3 correspondence of 2 to N, part or all of suspension rod 4 is provided with the locating part 5 of the spacing of described suspension rod 4 top of restriction and upper supporting plate 2.In the present embodiment, be numbered in the suspension rod 4 of freeze-drying plate layer 3 correspondence of 2 to N, the suspension rod 4 of part is provided with the locating part 5 of the spacing of described suspension rod 4 top of restriction and upper supporting plate 2, by arranging the locating part 5 limiting this suspension rod 4 length on the suspension rod 4 of specific freeze-drying plate layer 3 correspondence, namely except being numbered 1,1+1M, 1+2M, 1+3M ..., 1+nM freeze-drying plate layer 3 outside, all the other suspension rods 4 corresponding to freeze-drying plate layer 3 are provided with locating part 5, wherein, n is natural number, and M is the natural number of more than 2.The position of each freeze-drying plate layer 3 can be regulated arbitrarily, thus change the spacing of freeze-drying plate layer 3, compared with forming single constant flaggy spacing with freeze-drying plate layer in prior art 3, structure is ingenious, change the flaggy spacing size of freeze dryer, be applicable to more greatly, the bottle freeze-drying of more polytypic, expand the working range of freeze dryer, saved cost.
In the present embodiment, block 6 is arranged at each suspension rod 4 top, and locating part 5 is between block 6 and upper supporting plate 2 and against upper supporting plate 2, the locating part 5 on each suspension rod 4 is identical with the distance between block 6.Locating part 5 is clip 51 and alignment pin 52, clip 51 is provided with draw-in groove 511, the inwall of draw-in groove 511 is provided with installing hole 512, alignment pin 52 to be placed in installing hole 512 and to be connected with the inner thread of installing hole 512, installing hole 512 is stretched out in one end of the close draw-in groove 511 of alignment pin 52, and suspension rod 4 surface is provided with the locating hole 41 coordinated with alignment pin 52, the adjustable position of alignment pin 52 in installing hole 512, to adjust the clamping force of alignment pin 52 in locating hole 41, to prevent getting loose of clip 51.Draw-in groove 511 is set to square, and suspension rod 4 is provided with the flat horizontal surface 42 corresponding with draw-in groove 511, and locating hole 41 is located on flat horizontal surface 42, effectively can prevent clip 51 from rotating relative to suspension rod 4 because of vibration, thus get loose phenomenon.When there is no clip 51, after freeze-drying plate layer 3 stretches, the top of suspension rod 4 and upper supporting plate 2 against, after loading clip 51, suspension rod 4 upper part because clamping with clip 51, and can not pass upper supporting plate 2, thus shortens the length of suspension rod 4.
In the present embodiment, every block freeze-drying plate layer 3 edge is provided with hanger 7, and each suspension rod 4 lower end is passed hanger 7 and is connected with an acorn nut 8.The edge of upper supporting plate 2 is installed with boatswain chair 9, and suspension rod 4 is arranged in boatswain chair 9, and locating part 5 is against boatswain chair 9 upper surface.
In the present embodiment, boatswain chair 9 is set to four, is distributed in the both sides of upper supporting plate 2, every side is provided with two, each boatswain chair 9 upper hanger 4 quantity is identical with freeze-drying plate layer 3 quantity, and each freeze-drying plate layer 3 to be sling support by four suspension rods 4, adds the stability that freeze-drying plate layer 3 is sling.
Shown in Fig. 1, in the present embodiment, N is 16, suspension rod 4 quantity on each boatswain chair 9 is 16,16 suspension rods 4 are evenly divided into two rows, two suspension rod 4 intervals of two adjacent freeze-drying plate layer 3 correspondences are arranged (shown in Fig. 4), and wherein, two adjacent freeze-drying plate layer 3 intervals arrange it is that when preventing freeze-drying plate layer 3 superimposed, suspension rod 4 lower end interferes with each other.In the present embodiment, n is 1, M is 2, except being numbered 1,3,5,7 ..., 15 freeze-drying plate layer 3 outside, all the other suspension rods 4 corresponding to freeze-drying plate layer 3 are provided with the locating part 5 of the spacing of restriction suspension rod 4 top and upper supporting plate 2, and the suspension rod 4 corresponding to freeze-drying plate layer 3 being namely numbered even number is provided with locating part 5.
Fig. 5 is the deployed condition of front 8 freeze-drying plate layers 3 in 16 freeze-drying plate layers 3, being numbered of front 8 freeze-drying plate layers 3: 1# flaggy, 2# flaggy, 3# flaggy, 4# flaggy, 5# flaggy, 6# flaggy, 7# flaggy, 8# flaggy, corresponding suspension rod 4 is: 1# suspension rod, 2# suspension rod, 3# suspension rod, 4# suspension rod, 5# suspension rod, 6# suspension rod, 7# suspension rod, 8# suspension rod, all the other the like; Wherein, 2# suspension rod, 4# suspension rod, 6# suspension rod, 8# suspension rod are provided with clip 51, and namely odd numbers suspension rod 4 is offseted by block 6 and boatswain chair 9, and 4, even numbers suspension rod is offseted by clip 51 and boatswain chair 9.Each freeze-drying plate layer 3 original state is for mutually shrinking and being superimposed together, when upper supporting plate 2 rises under the driving being elevated actuator, 1# flaggy is sling by 1# suspension rod, then and then upper supporting plate 2 ascending motion, because 2# suspension rod is provided with clip 51, clip 51 is resisted against on boatswain chair 9, the length of slinging of 2# suspension rod shortens, make 2# flaggy cannot be separated 1# flaggy, 2# suspension rod rises with boatswain chair 9, 2# flaggy rises together with 1# flaggy, 2# flaggy is separated with 3# flaggy, boatswain chair 9 continues to rise, until the block 6 of 3# suspension rod offsets with boatswain chair 9, 3# flaggy is sling by 3# suspension rod, along with boatswain chair 9 continues to rise, until all freeze-drying plate layers 3 are lifted, as shown in Figure 5.Now, the gap of 1# flaggy and 2# flaggy is that L2(is very little, also can ignore), 2# flaggy and 3# flaggy gap are L1, and other flaggy gaps are L1, wherein, L1=2L-L2.L is the gap of (when not adopting the locating part 5 of the present embodiment) 1# flaggy and 2# flaggy in prior art, as shown in Figure 10, if the spacing of flaggy spacing L(and single freeze-drying plate layer 3 and single freeze-drying plate layer 3 in prior art) be 150mm, according to above-mentioned formula, the freeze-drying plate layer spacing so in the present embodiment is L1=2 × 150-L2.Need to leave ebb interval between the desirable 15mm(flaggy of general L2), calculating flaggy spacing L1 in the present embodiment is thus 285mm, can the bottle of freeze-drying be of a size of between 0-285mm, and in prior art, can the bottle of freeze-drying be of a size of between 0-150mm.By the effect of the locating part 5 of the present embodiment, the equally spaced flaggy spacing of freeze-drying plate layer 3 gap-forming that the freeze-drying plate layer 3 and the lower floor two pieces that are fitted in two pieces, upper strata fit, with by one piece of freeze-drying plate layer 3 in prior art compared with one piece of freeze-drying plate layer 3 gap-forming flaggy spacing, freeze-drying plate layer spacing increases, be applicable to the bottle freeze-drying of larger number, expand the working range of freeze dryer, save cost.
Except the present embodiment, M can also be 3, three freeze-drying plate layers 3 are superimposed together, namely when N is 16, except being numbered 1, 4, 7, 10, 13, outside the freeze-drying plate layer 3 of 16, be numbered 2, 3, 5, 6, 8, 9, 11, 12, 14, the corresponding suspension rod 4 sent out of freeze-drying plate layer 3 of 15 is provided with locating part 5, thus three freeze-drying plate layers 3 are superimposed together, be numbered between the freeze-drying plate layer 3 of 3 and the freeze-drying plate layer 3 being numbered 4 and form larger flaggy spacing, the i.e. freeze-drying plate layer 3 of three pieces, upper strata laminating and the three pieces of freeze-drying plate layer of fitting 3 gap-forming flaggy spacing of lower floor, now L1 '=3 × 150-2 × L2=420mm > 285mm.
Embodiment 2
As shown in Figure 9, the freeze dryer that the freeze-drying plate layer spacing of the present embodiment is adjustable is substantially identical with the structure of embodiment 1, difference is, in the present embodiment, be numbered in the suspension rod 4 of freeze-drying plate layer 3 correspondence of 2 to N, whole suspension rods 4 is provided with the locating part 5 of the spacing of described suspension rod 4 top of restriction and upper supporting plate 2, namely except the suspension rod 4 of first freeze-drying plate layer 3 correspondence, the suspension rod 4 of all the other freeze-drying plate layer 3 correspondences is equipped with locating part 5.By the effect of locating part 5, in the process that freeze-drying plate layer 3 launches, 1# flaggy and 2# flaggy keep superimposed constant, 3# suspension rod arranges locating part 5, locating part 5 is less than 2# suspension rod upper limit part 5 apart from place suspension rod 4 distance from top apart from the distance at place suspension rod 4 top, now 3# flaggy is separated with 2# flaggy, and spacing is L3, 4# suspension rod arranges locating part 5 simultaneously, with make 4# flaggy and 3# flaggy superimposed, the like, regulate the position of each suspension rod 4 upper limit part 5, form the flaggy spacing in the gap such as not as shown in Figure 10, the spacing of 4# flaggy and 5# flaggy is L4, the spacing of 6# flaggy and 7# flaggy is L4, L3 < L1, L4 < L1, L5 < L1, L3, L4, unequal mutually between L5, to adjust unequal freeze-drying plate layer spacing, same freeze dryer has the flaggy gap varied in size, multi-size, the bottle of different model can be placed simultaneously.
Except the present embodiment, by regulating the distance of the locating part 5 on each suspension rod 4, equal freeze-drying plate layer spacing can also be adjusted, i.e. L3=L4=L5 < L1.In addition, by regulating the position of the locating part 5 on 4# suspension rod, to make 4# flaggy be separated with 3# flaggy, less flaggy spacing can also between 4# flaggy, be formed.
Although the utility model discloses as above with preferred embodiment, but and be not used to limit the utility model.Any those of ordinary skill in the art, when not departing from technical solutions of the utility model scope, the technology contents of above-mentioned announcement all can be utilized to make many possible variations and modification to technical solutions of the utility model, or be revised as the Equivalent embodiments of equivalent variations.Therefore, every content not departing from technical solutions of the utility model, according to the utility model technical spirit to any simple modification made for any of the above embodiments, equivalent variations and modification, all should drop in the scope of technical solutions of the utility model protection.

Claims (9)

1. the freeze dryer that a freeze-drying plate layer spacing is adjustable, comprise freeze-drying chamber (1), liftable upper supporting plate (2) is provided with in described freeze-drying chamber (1), the below of described upper supporting plate (2) is provided with N block freeze-drying plate layer (3), described N block freeze-drying plate layer (3) from top to bottom number consecutively is 1, 2, N, N >=2, every block freeze-drying plate layer (3) correspondence is provided with suspension rod (4), each suspension rod (4) is all arranged in described upper supporting plate (2) and goes up and each freeze-drying plate layer (3) can be driven respectively to be elevated by described upper supporting plate (2), it is characterized in that: be numbered in the suspension rod (4) of freeze-drying plate layer (3) correspondence of 2 to N, part or all of suspension rod (4) is provided with the locating part (5) of the spacing of restriction described suspension rod (4) top and upper supporting plate (2).
2. the freeze dryer that freeze-drying plate layer spacing according to claim 1 is adjustable, it is characterized in that: except being numbered 1,1+1M, 1+2M, 1+3M ..., 1+nM freeze-drying plate layer (3) outside, suspension rod (4) corresponding to all the other freeze-drying plate layers (3) is provided with the locating part (5) of the spacing of restriction described suspension rod (4) top and upper supporting plate (2), wherein, n is natural number, and M is the natural number of more than 2.
3. the freeze dryer that freeze-drying plate layer spacing according to claim 1 is adjustable, it is characterized in that: described locating part (5) is clip (51) and alignment pin (52), described clip (51) is provided with draw-in groove (511), the inwall of described draw-in groove (511) is provided with installing hole (512), described alignment pin (52) to be placed in described installing hole (512) and to be connected with the inner thread of installing hole (512), described installing hole (512) is stretched out in one end of the close draw-in groove (511) of described alignment pin (52), described suspension rod (4) surface is provided with the locating hole (41) coordinated with described alignment pin (52).
4. the freeze dryer that freeze-drying plate layer spacing according to claim 3 is adjustable, it is characterized in that: described draw-in groove (511) is set to square, described suspension rod (4) is provided with the flat horizontal surface (42) corresponding with described draw-in groove (511), and described locating hole (41) is located on described flat horizontal surface (42).
5. the freeze dryer that freeze-drying plate layer spacing according to any one of claim 1 to 4 is adjustable, each suspension rod (4) top is provided with block (6), described locating part (5) is positioned between block (6) and upper supporting plate (2) and against described upper supporting plate (2), the locating part (5) on each suspension rod (4) is identical with the distance between block (6).
6. the freeze dryer that freeze-drying plate layer spacing according to claim 5 is adjustable, is characterized in that: every block freeze-drying plate layer (3) edge is provided with hanger (7), and each suspension rod (4) lower end is passed described hanger (7) and is connected with an acorn nut (8).
7. the freeze dryer that freeze-drying plate layer spacing according to claim 5 is adjustable, it is characterized in that: the edge of described upper supporting plate (2) is installed with boatswain chair (9), described suspension rod (4) is arranged in described boatswain chair (9), and described locating part (5) is against described boatswain chair (9) upper surface.
8. the freeze dryer that freeze-drying plate layer spacing according to claim 7 is adjustable, it is characterized in that: described boatswain chair (9) is set to four, be distributed in the both sides of upper supporting plate (2), every side is provided with two, and each boatswain chair (9) upper hanger (4) quantity is identical with freeze-drying plate layer (3) quantity.
9. the freeze dryer that freeze-drying plate layer spacing according to claim 8 is adjustable, it is characterized in that: N is 16, suspension rod (4) quantity on each boatswain chair (9) is 16,16 described suspension rods (4) are evenly divided into two rows, and two suspension rod (4) intervals that two adjacent freeze-drying plate layers (3) are corresponding are arranged.
CN201520491827.7U 2015-07-09 2015-07-09 Freeze -drying sheet layer interval adjustable freeze dryer Active CN204881129U (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106643118A (en) * 2016-12-14 2017-05-10 邵阳学院 Double spaced material layer plate
CN110494708A (en) * 2017-03-22 2019-11-22 罗伯特·博世有限公司 Freeze-drier

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106643118A (en) * 2016-12-14 2017-05-10 邵阳学院 Double spaced material layer plate
CN110494708A (en) * 2017-03-22 2019-11-22 罗伯特·博世有限公司 Freeze-drier
CN110494708B (en) * 2017-03-22 2021-08-03 Sbm舍勒-布勒克曼医疗技术有限公司 Freeze-drying equipment

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Changsha Pharmaceutical Equipment Industrial Technology Research Institute Co.,Ltd.

Assignor: TRUKING TECHNOLOGY Ltd.

Contract record no.: X2023980051833

Denomination of utility model: Freeze drying machine with adjustable interlayer spacing for freeze-dried boards

Granted publication date: 20151216

License type: Common License

Record date: 20231213

EE01 Entry into force of recordation of patent licensing contract