CN204814875U - Take humidity regulation's fluidized bed capsule machine - Google Patents
Take humidity regulation's fluidized bed capsule machine Download PDFInfo
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- CN204814875U CN204814875U CN201520555715.3U CN201520555715U CN204814875U CN 204814875 U CN204814875 U CN 204814875U CN 201520555715 U CN201520555715 U CN 201520555715U CN 204814875 U CN204814875 U CN 204814875U
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Abstract
The utility model provides a take humidity regulation's fluidized bed capsule machine, including first air -conditioning box and second air -conditioning box, be equipped with in proper order in the first air -conditioning box and just imitate filtration unit and well effect filtration unit, be equipped with freeze drying unit, heating unit and high -efficient filtration unit in the second air -conditioning box in proper order, first air -conditioning box and second air -conditioning box are linked together through the tee bend pipeline, install first blast gate on the spinal branch pipe in the tee bend pipeline, install second blast gate and runner dehumidification unit on another spinal branch pipe, be connected with the humidification unit between heating unit and the high -efficient filtration unit. The utility model provides a take humidity regulation's fluidized bed capsule machine, structural design is reasonable, and degree of automation is high, convenient to use, maneuverability and repeatability are strong, can improve production efficiency by a wide margin to ensureing that the quality is controllable, being fit for the industrial production of scale, the using value is huge.
Description
Technical field
This utility model relates to the technical field of pharmaceutical equipment, is specifically related to a kind of fluidized-bed coating machine with humidity regulation.
Background technology
Near domestic pharmaceutical machine industry is meet the requirement that pharmacy industry reaches GMP during the last ten years, introducing, digesting, absorbing on the basis of advanced foreign technology, continually develops out advanced pharmaceutical equipment.In the process equipment of the slow controlled release granule of solid preparation, piller, micropill, tablets and other formulations, update from traditional comet shepherd's purse pot, successively have developed the coating equipment in sugar production line such as centrifugal seed-coating machine, efficient atresia seed-coating machine, its common architectural feature is: have air filtering system, air inlet system, heating system, spraying system and induced draught system, its weak point is: coating efficiency is not high, coating material waste is comparatively large, and coating quality is not satisfactory.
Subsequently, the drying device industrial at preparation improves, has developed fluidized-bed coating machine, fluid bed has the kind such as back-mixing stream, piston flow, eddy flow, vibration, contact, multicompartment fluidized bed, as application number a kind of spiral-flow type fluidized bed coater disclosed in the Chinese utility model patent of 201020183818.9; Fluid bed main device is point open-type and a closed circuit.The advantage of this equipment is: integrated atomization operating system and coated systems, in one, make the granulation of medicine, micropill processed, coating and drying process once complete in fluid bed, reduce and generate energy consumption, improve coating efficiency.
Current pharmaceutical factory, fluidized-bed coating machine is mainly used in granulation and the drying of medicine, the structural allocation of its wind inlet section as shown in Figure 1, generally include as lower part: 1. just imitate air filter (containing first effect air filter unit a), middle effect air filter (containing middle effect air filter unit b), these two parts are installed in a cuboid air-conditioning box be communicated with air inlet; 2. dehumidifier (containing freeze drying unit c), heater (containing heating unit d), high efficiency particle air filter (containing high-efficiency air filtering unit e), these three parts are installed in the cuboid air-conditioning box of another entirety; 3. the cuboid air-conditioning box of another entirety, uses the intake stack of Flange joint to lead to fluidized-bed coating machine, at intake stack distal aperture, device for monitoring temperature (containing control temperature unit f) is housed.During work, air, through passing into from air inlet, successively through the member unit of aforementioned several fluid bed wind inlet section, enters into fluid bed cavity, and through spraying system and coated systems, completes production.
Current fluidized-bed coating machine, before air enters fluid bed cavity, controls air intake humidity by the freeze drying unit of dehumidifier, thus reaches the technological requirement of pharmaceutical production; Generally, also can meet the process conditions of most pharmaceutical preparation, but also there is many technical limitations:
1, most pharmaceutical factory, winter seldom supplies chilled water, therefore cannot use freeze drying function, and when the rainy day in winter, air intake humidity can be higher, causes increase drying time, affect drying efficiency, is unfavorable for the quality control of product.
2, some high-end sustained-release preparation (such as slow-release micro-pill etc.), because the characteristic of coating material is different, adopt during fluidized bed coating and must have strict process conditions, existing equipment, owing to being difficult to regulation and control air intake humidity, causes being difficult to meet high-end sustained-release preparation art for coating requirement.Such as, if if coating process air intake humidity is too low, spraying dry phenomenon can be caused, waste coating material; If air intake humidity is too high, the drying of clothing film can be caused not in time, produce the situation of micropill adhesion.Although above-mentioned shortcoming can be improved by regulating other parameter such as intake, hydrojet speed, but adjustable extent is very little, because once regulate these parameters, the fluidized state of coating material, the atomizing effect etc. of spray gun will be affected, so cause existing equipment to be difficult to regulation and control air intake humidity, affect coating effect, finally cause the release of product to control to there is relatively large deviation, be unfavorable for the quality control of product.
In sum, how to improve existing fluidized-bed coating machine structure, there is provided a kind of and can effectively monitor, controlled humidity fluidized-bed coating machine, make it before entering fluid bed cavity, just can meet the process conditions of coating, solving the technological deficiency of existing equipment, is the technical barrier that those skilled in the art are badly in need of solving.
Utility model content
This utility model provides a kind of fluidized-bed coating machine with humidity regulation, variously possesses the wet functional unit of dehumidifying, control by setting up, and what solve that prior art exists can not poor, the technological deficiency that affects Drug's control of regulating and controlling humidity, coating effect.
The technical scheme that this utility model adopts is specific as follows:
A kind of fluidized-bed coating machine with humidity regulation, comprise the first air-conditioning box and the second air-conditioning box, just effect air filter unit and middle effect air filter unit is provided with successively in first air-conditioning box, freeze drying unit, heating unit and high-efficiency air filtering unit is provided with successively in second air-conditioning box, first air-conditioning box is connected by triplate line with the second air-conditioning box, an arm in triplate line is provided with the first air-valve, another root arm is provided with the second air-valve and rotary wheel dehumidifying unit; Humidifying unit is connected with between heating unit and high-efficiency air filtering unit.
Preferably, humidifying unit is connected with the second air-conditioning box by air inlet pipe.In this utility model, humidifying unit is mainly used in improving air intake humidity.
Preferred, rotary wheel dehumidifying unit is connected with assembly control system separately with humidifying unit.In this utility model, rotary wheel dehumidifying unit is mainly used in reducing air intake humidity.
Preferably, triplate line is Y-shaped three-way pipe.
Preferred, one end of triplate line is connected with middle effect air filter unit, and one end is connected with freeze drying unit, and one end is connected with rotary wheel dehumidifying unit.In this utility model, triplate line according to outside humidity and production technology to the deviation situation of air intake humidity requirement, can be selected rotary wheel dehumidifying and freeze drying to open simultaneously, or only opens freeze drying.
Preferably, the first air-conditioning box is connected with air inlet by the first pipeline, and the second air-conditioning box is connected with fluid bed cavity by second pipe.
Preferred, second pipe is provided with perforate, and tapping is connected with temperature monitor and moisture monotor.In this utility model, temperature monitor is mainly used in display and controls heating unit heats amount, and moisture monotor is mainly used in display and controls humidifying unit adding moisture.
Preferably, the junction of the second air-conditioning box and second pipe, is provided with venting of dust explosion device.In this utility model, the Main Function of venting of dust explosion device is: when producing explosion time in fluidized-bed coating machine cavity, the pressure of generation discharges from here, to ensure personnel and Factory Building safety.
A kind of fluidized-bed coating machine with humidity regulation that this utility model provides, the operation principle of each parts is as follows: rotary wheel dehumidifying unit adopts steam-heated mode, carries out on-off control by the switch board be arranged in clean area; Humidifying unit adopts the mode of electrode humidifler, by purified water as water source, is undertaken adding moisture control by the switch board be arranged in clean area.Aforesaid two switch boards, are all connected with the assembly control system in clean area, belong to the unit controls module of functional independence.Control module is by the feedback signal of humidity detection device, and what control humidifier according to setting value adds moisture.
In this utility model, the first air-valve on triplate line and the second air-valve can according to practical situation selectively unlockings, to meet the requirement of various processes to air intake humidity.Such as, when outside humidity is higher than the requirement of production technology to air intake humidity, then the first air-valve cuts out, the second air-valve opens, and now humidity reduces by air intake after rotary wheel dehumidifying, freeze drying, and then by humidifying unit, the humidity of air intake is adjusted to desirable value; Otherwise when outside humidity is lower than the requirement of production technology to air intake humidity, then the first air-valve card is opened, the second air-valve cuts out, and now can not open rotary wheel dehumidifying, directly after freeze drying, through humidifying unit, air intake humidity can be adjusted to desirable value.
A kind of fluidized-bed coating machine with humidity regulation that this utility model provides, reasonable in design, automaticity is high, easy to use, operability and repeatability strong; By setting up humidity regulation module (as rotary wheel dehumidifying unit, humidifying unit, moisture monotor etc.), significantly can regulate and control air intake humidity, to meet the requirement of various processes to humidity, improving the coating stability of material; In addition, under the working condition being unable to supply chilled water can also being waited in the winter time, guarantee air intake humidity controllable, the drying of material, coating effect can not be affected.In a word, the fluidized-bed coating machine using this utility model to provide, significantly can enhance productivity, and guarantee quality controllable, and be applicable to the commercial production of scale, using value is huge.
Accompanying drawing explanation
Fig. 1 is the structural representation of existing fluidized-bed coating machine.
The structural representation of the fluidized-bed coating machine that Fig. 2 provides for this utility model.
Detailed description of the invention
As shown in Figure 2, a kind of fluidized-bed coating machine with humidity regulation, comprise the first air-conditioning box 1 and the second air-conditioning box 2, be provided with successively in first air-conditioning box 1 just to imitate in air filter unit 101 and middle effect air filter unit 102, second air-conditioning box 2 and be provided with freeze drying unit 201, heating unit 202 and high-efficiency air filtering unit 203 successively.The Y-type three way type pipeline 3 of Flange joint is added after the first air-conditioning box 1, connect the second air-conditioning box 2 and rotary wheel dehumidifying unit 4 respectively, that is, one end of triplate line 3 with in the first air-conditioning box 1 in imitate air filter unit 102 and be connected, one end is connected with freeze drying unit 201, and one end is connected with rotary wheel dehumidifying unit 4; In addition, this road arm be connected with freeze drying unit 201, is provided with the first air-valve 301, and this road arm be connected with rotary wheel dehumidifying unit 4, is provided with the second air-valve 302.
Further, in the second air-conditioning box 2, between heating unit 202 and high-efficiency air filtering unit 203, add air inlet pipe 501, after the casing of through second air-conditioning box 2 of air inlet pipe 501, be connected with humidifying unit 5.Rotary wheel dehumidifying unit 4 and humidifying unit 5, be connected with the assembly control system 8 in clean area separately, belongs to the unit controls module of functional independence.
In this utility model, the first air-conditioning box 1 upper flange is connected with the first pipeline 103, and the first effect air filter unit 101 in the first air-conditioning box 1 is connected with air inlet by the first pipeline 103; Second air-conditioning box 2 upper flange is connected with second pipe 204, and the high-efficiency air filtering unit 203 in the second air-conditioning box 2 is connected with fluid bed cavity by second pipe 204.Second pipe 204 is provided with 2 perforates, and one of them tapping is connected with temperature monitor (containing control temperature unit 6), and another tapping is connected with moisture monotor (containing the wet unit 7 of control).
In addition, between the second air-conditioning box 2 and second pipe 204, can also select to increase venting of dust explosion device (containing antibomb unit) according to practical situation, so that solve the hidden peril of explosion because the reasons such as pressure is excessive produce.
In this utility model, for ease of daily maintenance, replacing and detection, just effect air filter unit 101, middle effect air filter unit 102 and high-efficiency air filtering unit 203, the mode all adopting buckle to connect is installed in casing; Freeze drying unit 201, heating unit 202, rotary wheel dehumidifying unit 4 and humidifying unit 5, all adopt the mode be threaded to install; The pipelines such as triplate line 3, air inlet pipe 501, first pipeline 103, second pipe 204, all adopt Flange joint.Certainly, aforesaid connected mode is only applicating example, includes but not limited to be fixedly connected with or be flexibly connected.
In this utility model, triplate line 3 can be aforesaid Y-piece, also can be the pipeline of T-shaped pipe or other shapes, as long as threeway demand can be met.
Be below three applicating examples of this utility model device, its object is to the using value that this device is better described.
Application examples one:
Medicine slow-release micro-pill art for coating is a kind of novel drug preparation technique, by wrapping up one deck extended release coatings film containing outside pill core, can control the rate of release of medicine.
Extended release coatings film coating material is divided into ethanol-soluble type and water-soluble two kinds usually, because ethanol-soluble type coating material solvent alcohol evaporation rate is very fast, if coating process air intake humidity is too low, can cause spraying dry phenomenon, waste coating material.If water-soluble coating material, because aqueous solvent evaporation rate is comparatively slow, if coating process air intake humidity is too high, the situation of the dry micropill adhesion not in time of clothing film can be caused.Although above situation can be improved by regulating other parameter such as intake and hydrojet speed, adjustable extent is very little, because these parameters can affect the fluidized state of coating material, and the atomizing effect etc. of spray gun.
So this utility model device effectively can control the humidity range of air intake, fundamentally solves problem, the versatility of equipment is strengthened greatly, various coating material can be applicable to.
Application examples two:
This utility model device solves pharmaceutical factory when not having chilled water to supply winter, and air intake humidity is too high, the problem that cannot reduce.
Such as, in certain product coating process in winter, first while empty machine preheating, operator observes the control panel that is arranged in clean area (containing assembly control system 8, lower same), find that air intake humidity is higher than technological requirement scope, owing to not having chilled water supply, the original freeze drying unit 201 of device cannot start, so operator open rotary wheel dehumidifying unit 4 and humidifying unit 5 on the control panel, now the first air-valve 301 cuts out, and the second air-valve 302 is opened.Air intake humidity can be reduced to enough low after working by rotary wheel dehumidifying unit 4, and humidifying unit 5 adds moisture according to the Signal Regulation of moisture monotor (containing the wet unit 7 of control), air intake humidity is adjusted in the scope of technological requirement.
Application examples three:
Generally, the chilled water temperature pharmaceutical factory in summer controls at 7 ~ 9 DEG C usually, but when the plum rain season in summer, outdoor environment is high humidity extremely, now chilled water temperature generally needs to be reduced to 4 DEG C even lower, could adjust in the scope of technological requirement by the humidity of air intake, its result causes the energy consumption of meeting equipment greatly to improve.And this device adds the stronger rotary wheel dehumidifying of dehumidifying effect, carry out auxiliary freeze drying, reach energy-saving and cost-reducing object.
Such as, in certain product south plum rain season coating process, first while empty machine preheating, operator observes the control panel that is arranged in clean area (containing assembly control system 8, lower same), now the first air-valve 301 is opened under normal circumstances, first air-valve 302 cuts out, and freeze drying unit 201 is opened, and finds that humidity cannot be reduced in the scope of technological requirement.So operator open rotary wheel dehumidifying unit 4 and humidifying unit 5 on the control panel, now the first air-valve 301 is opened, and the first air-valve 302 is opened.Rotary wheel dehumidifying unit 4 and freeze drying unit 201 work simultaneously, air intake humidity can be reduced to enough low, subsequently, humidifying unit 5 adds moisture according to the Signal Regulation of moisture monotor (containing the wet unit 7 of control), air intake humidity is adjusted in the scope of technological requirement.
Claims (8)
1. the fluidized-bed coating machine with humidity regulation, comprise the first air-conditioning box (1) and the second air-conditioning box (2), be provided with successively in first air-conditioning box (1) and just imitate air filter unit (101) and middle effect air filter unit (102), freeze drying unit (201) is provided with successively in second air-conditioning box (2), heating unit (202) and high-efficiency air filtering unit (203), it is characterized in that, described the first air-conditioning box (1) is connected by triplate line (3) with the second air-conditioning box (2), an arm in triplate line (3) is provided with the first air-valve (301), another root arm is provided with the second air-valve (302) and rotary wheel dehumidifying unit (4), humidifying unit (5) is connected with between described heating unit (202) and high-efficiency air filtering unit (203).
2. the fluidized-bed coating machine of band humidity regulation according to claim 1, is characterized in that, described humidifying unit (5) is connected with the second air-conditioning box (2) by air inlet pipe (501).
3. the fluidized-bed coating machine of band humidity regulation according to claim 1 and 2, is characterized in that, described rotary wheel dehumidifying unit (4) is connected with assembly control system (8) separately with humidifying unit (5).
4. the fluidized-bed coating machine of band humidity regulation according to claim 1, is characterized in that, described triplate line (3) is Y-shaped three-way pipe.
5. the fluidized-bed coating machine of the band humidity regulation according to claim 1 or 4, it is characterized in that, one end of described triplate line (3) is connected with middle effect air filter unit (102), one end is connected with freeze drying unit (201), and one end is connected with rotary wheel dehumidifying unit (4).
6. the fluidized-bed coating machine of band humidity regulation according to claim 1, it is characterized in that, described the first air-conditioning box (1) is connected with air inlet by the first pipeline (103), and the second air-conditioning box (2) is connected with fluid bed cavity by second pipe (204).
7. the fluidized-bed coating machine of band humidity regulation according to claim 6, is characterized in that, described second pipe (204) is provided with perforate, and tapping is connected with temperature monitor (6) and moisture monotor (7).
8. the fluidized-bed coating machine of the band humidity regulation according to claim 6 or 7, is characterized in that, described the second air-conditioning box (2) and the junction of second pipe (204), be provided with venting of dust explosion device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520555715.3U CN204814875U (en) | 2015-07-28 | 2015-07-28 | Take humidity regulation's fluidized bed capsule machine |
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| CN201520555715.3U CN204814875U (en) | 2015-07-28 | 2015-07-28 | Take humidity regulation's fluidized bed capsule machine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111080921A (en) * | 2019-12-20 | 2020-04-28 | 温州匠振科技有限公司 | Clothing borrowing and returning cabinet |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111080921A (en) * | 2019-12-20 | 2020-04-28 | 温州匠振科技有限公司 | Clothing borrowing and returning cabinet |
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