CN204723023U - A kind of Wearable pupillary light reflex measurement device - Google Patents

A kind of Wearable pupillary light reflex measurement device Download PDF

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CN204723023U
CN204723023U CN201420784481.5U CN201420784481U CN204723023U CN 204723023 U CN204723023 U CN 204723023U CN 201420784481 U CN201420784481 U CN 201420784481U CN 204723023 U CN204723023 U CN 204723023U
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pupil
wearable
measurement device
handling equipment
pupillary
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张克忠
黄明
戴亚康
许昌红
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Abstract

The utility model proposes a kind of Wearable pupillary light reflex measurement device, comprise thermal camera, infrared light compensating lamp, stimulating light source, the Wearable helmet, pupil correcting imaging system, pupil monitoring camera, data handling equipment and pupillometry software system.Pupillometry software system comprises physical size measuring system, physiologic information computing system, clinical report generation system, is configured in data handling equipment.Other hardware configuration, in the Wearable helmet, realize the analyses such as the dimensional measurement of person under inspection's pupil aperture, iris area measurement, the drafting of pupil aperture change curve, obtain the screening results of nervous system disease, form clinical report.This equipment can greatly alleviate clinical staff's working strength, and improves the precision of pupillary reflex diagnosis, is well suited for the medical applications of the association areas such as Clinical Ophthalmology, neurosurgery, psychiatric section.

Description

A kind of Wearable pupillary light reflex measurement device
Technical field
This utility model relates to a kind of Wearable pupillary light reflex measuring system, be specifically related to a kind of Wearable pupillary light reflex measurement device comprising thermal camera, infrared light compensating lamp, stimulating light source, the Wearable helmet, device of widening the view, data handling equipment and pupillometry software system, be suitable for the medical applications of Clinical Ophthalmology, neurosurgery, psychiatric section and association area thereof.
Background technology
Eyes are one of very important organs of human body.PLR is that light stimulation causes miotic one reaction, completes this reaction by luminous reflectance path.Pupillary light reflex path, from retina, through optic nerve, optic chiasma and tractus opticus, then through arrival pretectal area, upper arm mound.The aixs cylinder of accessory nucleus of oculomotor nerve changes neuron through oculomotorius to ciliary ganglion, and postganglionic fibers domination sphincter pupillae, causes bilateral contracted pupil.In above-mentioned luminous reflectance path, any one damage all can cause luminous reflectance weaken or disappear, if utilization ratio of optical energy is low in addition, time less than 10%, light energy losses is had in light path, need to add stimulating light source, and this is not that a good compensating light stimulates to the system of human eye, tested patient's same feeling can feel dazzling and uncomfortable.
The size of normal pupil is relevant with factors such as age, physiological status, dioptric, external environments.When people is born, pupil is maximum, and pupil can diminish gradually with age.Normal pupil is diameter average out to 2.5 to 4 millimeters under available light, and both sides etc. are large, and neat in edge, can reduce under light, and the environment that light is dark can slightly increase.When eyes look straight ahead, with pupil light irradiation pupil, pupil can diminish immediately, and remove light source or closed eyes, pupil can restore.According to this characteristic of pupil, often use said method by detecting the functional activity of pupil thus the disease such as neuropathy, diabetic complication of examination patient clinically, simultaneously research is also had to point out, can as the basis for estimation of whether taking drugs by the functional check of pupillary light reflex.Except above-mentioned to except the Function detection of luminous reflectance, by the analysis to human eye physical state, the diseases such as injury of iris can be diagnosed out.
Thermal camera can catch the sightless ultrared reflected image of human eye, the thermal camera of active infrared camera technique is utilized to have infrared light compensating lamp, radiation surroundings, thus utilize infrared low-luminance color CCD to carry out catching of infrared radiation images.Infrared light compensating lamp has several wavelength of 715nm, 830nm and 950nm, although wherein the infrared light compensating lamp illumination distances of 715nm is far away, but can produce red sudden and violent phenomenon, namely produce the visible HONGGUANG of human eye when luminescence, the light compensating lamp of 830nm and 950nm does not then have red sudden and violent phenomenon substantially simultaneously.Because human eye is bound to produce reflection image under visible light, therefore the equipment being generally used for eye detection all adopts thermal camera to carry out the acquisition of eye image, to realize reducing the impact of eyeball surface reflected light for late detection when promoting clearness as far as possible simultaneously.
By doctor, a pupil lamp of tradition pupil detection equipment normally hand-held, by pupil light irradiation human eye, judges that the state of pupillary reflex is with the examination state of an illness.Also have and be integrated in the device of a similar pocket lamp by pupil lamp, thermal camera or visible light camera, take pictures while turning on pupil lamp, later stage manpower comparing is to the diagnosis carrying out the state of an illness.The shortcoming of existing equipment and method is:
1. there is large subjective error in the state of artificial judgment pupil change and aperture size;
2. the uncontrollable ambient lighting of hand-held pupil detector is for the impact of testing result, and therefore under different light environmental condition, same patient may produce different pupillary function reflexes;
3. be equipped with the pupil detection equipment of visible light camera, due to the luminous reflectance of eyeball surface, usually cannot carry out the accurate identification of pupil position;
4. the vertical pupil detection equipment volume of existing outfit eyeshield and dark room conditions is comparatively large, cannot meet the needs of to carry with or without the environment for use of laying plane, as complex sites such as natural disaster scene, battlefield, first aid scenes;
5. existing pupil detection equipment does not have lighting simulation function, cannot analyze the change of PLR function under varying environment optical condition.
6. existing stimulating light source does not compensate and correcting unit, and nictation, phenomenon was serious, and personal experience's effect is bad, and image quality is not high.
The equipment such as inventor wishes to utilize the wearable helmet, device of widening the view, thermal camera, infrared light compensating lamp, stimulating light source, supplementary lighting sources, pupil monitoring camera, design a kind of equipment that can realize continuous, the Accurate Measurement of PLR change under emulation photoenvironment, this equipment can be used for Clinical Ophthalmology, neurosurgery, the Illnesses Diagnoses of psychiatric Ke Deng section office and disease early screening etc.
Summary of the invention
The purpose of this utility model is to design a kind of portable pupillary light reflex measurement device with controlled photoenvironment, can measure under the illumination condition of specifying pupil to physiological features such as luminous reflectance functions, thus to improve based on the accuracy of the disorder in screening of pupillary reflex.The utility model proposes a kind of Wearable pupillary light reflex measurement device, comprise nine key components:
Thermal camera, has data communication with data handling equipment, for obtaining the video data of human eye;
Infrared light compensating lamp, for providing illumination for thermal camera;
Supplementary lighting sources is visible light source, for simulating the illumination under different scene;
Stimulating light source is visible light source, produces varying aperture for irradiating pupil to make pupil;
The Wearable helmet, for installing the said equipment, for user eye provides dark room conditions;
Pupil correcting imaging system, comprises the optical path of liquid crystal corrector or distorting lens composition;
Whether pupil monitoring camera, aim at well with described pupil correcting imaging systematic optical axis, simultaneously for single calibration imaging and short exposure correcting imaging for observer's eye pupil hole;
Pupillometry software system, comprises physical size measuring system, physiologic information computing system and report preparing system, for detecting the pupil in video data in real time, obtaining the physiologic information that pupil is relevant, and generating case report, being configured in data handling equipment;
Data handling equipment, based on the personal computer of X86 or X64 framework, or has the embedded platform of equal disposal ability, removable handheld device.
The data communication of thermal camera and data handling equipment is wire communication or wireless forms of communication; The quantity of thermal camera and stimulating light source is determined by the quantity of the pupil that will measure; The wavelength of its infrared light need mate the wavelength that adopted thermal camera can receive.
Supplementary lighting sources is made up of the luminescent device that can send visible ray, produces the light of different illumination, different frequency according to demand; The luminous function of luminescent device is controlled by the pupillometry software system be configured in data handling equipment, or is controlled by independent by-pass cock.
Stimulating light source luminance is controlled by the pupillometry software system be configured in data handling equipment, or is controlled by independent switch.
Select liquid crystal corrector to correct mutually as the wavefront position of optical path, pupil correcting imaging system comprises low order compensating glass, optical filter, half-wave plate, optical lens, polarization beam apparatus, location screen, annular diaphragm and wave front detector.
Wave front detector is high speed Hartmann sensor, pupil, liquid crystal corrector and Hartman wavefront detector Nonimage Conjugate Relations each other.
Pupillometry software system, the visible physical arrangement of outward appearance such as image data identification pupil wherein, iris, the white of the eye that physical size measuring system is wherein caught by infrared camera, and the size measuring often kind of structure.The structural parameters that physiologic information computing system can be obtained by physical size measuring system, calculate the dependency between each parameter, or the comparative between the different case of same parameters, obtain that pupil directly reflects, the quantitative analysis results of indirect reference function, and other are by the available related physiological parameters information of above-mentioned physical size.
Report preparing system wherein, can read the result of physiologic information computing system and physical size measuring system, and generates report with the higher text file format of versatility or picture file format.
Report preparing system wherein, has the data transmission interface with printer, facsimile machine, and has network data transmission interface.
Beneficial effect compared with traditional pupil detection equipment is:
1. complete equipment portability is stronger, is applicable to carrying with the emergent examination demand that also can adapt to the complicated occasions such as battlefield, natural disaster is on-the-spot, first aid is on-the-spot;
2. complete equipment flexibility ratio is higher, can adopt wired or wireless data transfer mode as required, and the removable handheld devices such as personal computer, embedded platform or smart mobile phone can be adopted as data handling equipment, to adapt to different use occasion requirements;
3. measurement result is more stable, by the Wearable helmet, effectively can reduce the burden of doctor and patient, because the distance of eye distance thermal camera, stimulating light source only changes in less scope after wearing the helmet, considerably reduce the impact of human error on measurement result.
4. the photoenvironment measured is controlled, can be realized the mensuration of pupillary light reflex function under the illumination of different illumination, different frequency by adjustment supplementary lighting sources;
5. measurement result more horn of plenty, not only can be obtained the measurement result of pupil diameter change, can also obtain the testing result of the every visible physical arrangement of eye, for clinical diagnosis provides more foundations by pupillometry software system;
6. adopt the method for confocal imaging to carry out imaging pupil; Tackling with the confocal aperture of pupil the veiling glare that other aspects of retina reflect by placing one in optical system, improve the contrast of imaging; There is compensation and correcting device simultaneously, human eye little to people's Eye irritation by single calibration is stable, image quality is high.
Accompanying drawing explanation
Fig. 1 is the system structure schematic diagram that this utility model proposes;
Fig. 2 is a kind of preferred embodiment surface structure top view proposed by the invention;
Fig. 3 is a kind of preferred embodiment surface structure front view proposed by the invention;
Fig. 4 is a kind of preferred embodiment pupil correcting imaging system schematic that this utility model proposes;
Fig. 5 is a kind of single calibration flow chart that this utility model proposes.
Element numbers illustrates: infrared light compensating lamp 1,5,9,13; Thermal camera 2,12; Stimulating light source 3,11; Supplementary lighting sources 6,8,14,16; USB connecting line 4,10; Rubber buffer 7,15; Bandage 17; Low order compensating glass 18; Location screen 19; Annular diaphragm 20; Pupil monitoring camera 21; Pin-hole filter-ing 22; Half-wave plate 23; Polarization beam apparatus 24; Thermal camera 25; High speed Hartmann sensor 26; Light source 27; Liquid crystal corrector 28; Human eye 29.
Detailed description of the invention
By particular specific embodiment, embodiment of the present utility model is described below, person skilled in the art scholar the content disclosed by this description can understand other advantages of the present utility model and effect easily.
Refer to Fig. 1 to Fig. 5.Notice, structure, ratio, size etc. that this description institute accompanying drawings illustrates, content all only in order to coordinate description to disclose, understand for person skilled in the art scholar and read, and be not used to limit the enforceable qualifications of this utility model, therefore the not technical essential meaning of tool, the adjustment of the modification of any structure, the change of proportionate relationship or size, do not affecting under effect that this utility model can produce and the object that can reach, still all should drop on technology contents that this utility model discloses and obtain in the scope that can contain.Simultaneously, quote in this description as " on ", D score, "left", "right", " centre " and " one " etc. term, also only for ease of understanding of describing, and be not used to limit the enforceable scope of this utility model, the change of its relativeness or adjustment, under changing technology contents without essence, when being also considered as the enforceable category of this utility model.
The system structure schematic diagram that accompanying drawing 1 proposes for this utility model, system is made up of the wearable helmet and pupillometry software system, and pupillometry software system is configured in data handling equipment.The data communication of the wearable helmet and data handling equipment by wired connection as modes such as USB, 1394 live wires, Ethernet interfaces, or by wireless connections as WIFI, bluetooth, NFC etc., the communication modes that this utility model adopts includes but not limited to aforesaid way;
In the wearable helmet, infrared light compensating lamp, stimulating light source, supplementary lighting sources and thermal camera are at least installed, stimulating light source direct projection pupil, the fixed position of thermal camera is ensureing to select according to the reality condition of installing under iris is positioned at the prerequisite of camera field of view, and supplementary lighting sources and infrared light compensating lamp should avoid direct projection human eye;
The shape of the wearable helmet includes but not limited to the helmet, eyeshield, glasses, observation box, everyly can be fixed on person under inspection's head by the fixed form such as bandage, support and the equipment being suitable for eye observation all belongs to wearable helmet category;
Infrared light compensating lamp in the wearable helmet, stimulating light source, supplementary lighting sources input two kinds of modes by the signal of manpower intervention and pupillometry software system and control;
Thermal camera in the wearable helmet and the pupillometry software system in data handling equipment have interactive communication, pupillometry software system can receive the video data that thermal camera imports into, and can control the shooting such as exposure, contrast, the white balance relevant parameter of thermal camera;
The each structure of physical size measuring system identifiable design eye in pupillometry software system is also measured its size, and at the appointed time can carry out continuous measurement to specified structure in scope;
Information interaction is had between physiologic information computing system in pupillometry software system and physical size measuring system, physiologic information computing system carries out the calculating of physiological parameter by the eye structure dimension information that physical size measuring system is imported into, and carries out further structure recognition and dimensional measurement according to result of calculation control physical size measuring system;
The result of physiologic information computing system and physical size measuring system all can input to report preparing system, clinical required parameters exported with the form of electronic health record or papery case history with the form of specifying, the form of the report generated includes but not limited to PDF document, WORD document, XML document, picture, papery printout etc.
Accompanying drawing 2,3 is the surface structure schematic diagram of this preferred embodiment, be respectively top view and front view, this preferred embodiment is the pupillary light reflex measurement device of eyeshield formula, infrared light compensating lamp 1,5,9,13 is comprised in eyeshield, wherein infrared light compensating lamp 1,5 and 9,13 is independent separately, can be regulated respectively by pupillometry software system or manpower intervention; Be provided with thermal camera 2,12 in eyeshield, thermal camera 2 and 12 can be controlled respectively by pupillometry software system and receive output data; Be provided with stimulating light source 3,11 in eyeshield, two stimulating light sources correspond respectively to left eye and right eye, and when eyes look straight ahead, the angle of cut of stimulating light source incident angle and eye sight line angle is less than 30 degree; Opaque dividing plate is had eyeshield to be separated into left and right Liang Ge observation ward in eyeshield between right and left eyes.
In this preferred embodiment, stimulating light source 3,11 adopts yellow LED lamp pearl, and luminous intensity is 25 millis candela (mcd), also can adopt other luminescent devices of the different luminous intensity of different spectral frequency according to clinical demand; Supplementary lighting sources 6,8,14,16 is installed in eyeshield, in this preferred embodiment, supplementary lighting sources adopts White LED as luminescent device, it is identical that direction of illumination and human eye look at direction straight, point to the orientation substrate being provided with thermal camera 2,12, have opaque dividing plate to block between luminescent device and human eye, supplementary lighting sources 6,8 and 14,16 independently can be controlled by manpower intervention or pupillometry software system;
In this preferred embodiment, the connected mode of eyeshield and data handling equipment is USB connecting line 4,10, transmits the video data of thermal camera 2,12 respectively, and imports the control signal of pupillometry software system into;
In this preferred embodiment, a kind of typical use scenes is: this eyeshield formula pupillary light reflex measurement device is fixed on head by bandage 17 by person under inspection, eyes eye socket is individually fixed in rubber buffer 7, on 15, eyes look straight ahead, infrared light compensating lamp 1, 5, 9, 13 send the sightless Infrared irradiation eyeshield inside of naked eyes, in this example, infrared light-emitting device is fixed in column structure, Infrared irradiation direction is parallel to substrate, the infrared light filling in eyeshield is realized by diffusing, supplementary lighting sources 6, 8, 14, 16 white lights sending 500 micro-candelas, expose to substrate, eyeshield inside is illuminated in diffusing of producing, the brightness of similar natural lighting is provided, person under inspection's pupil is made to be in normal size, then stimulating light source 3 and 11 is successively lighted, extinguish, thermal camera 2, 12 catch the eye video data of overall process and transfer to pupillometry software system, by the varying aperture of the physical size measuring system test constantly pupil of both eyes of pupillometry software system, and calculate the direct light reflex function of person under inspection's pupil of both eyes and the assessment result of indirect light reflex function by physiologic information computing system, pupil of both eyes varying aperture curve assessment result and physical size measuring system recorded is enumerated in same document, the report of PDF is exported by report preparing system,
Fig. 4 is a kind of preferred embodiment pupil correcting imaging system schematic that this utility model proposes, and as shown in the figure, light, after the process of dissipation speckle, enters open loop adaptive inertia weight system from light source to light path principle figure.Pupil, LCOS wave-front corrector and Hartman wavefront detector Nonimage Conjugate Relations each other; Only need by human eye place set-point light source during measurement response matrix, it is made to irradiate LCOS through light path, insert half-wave plate in the optical path, the light through LCOS reflection arrives Hartmann wave front sensor through a series of optical element simultaneously, takes out half-wave plate and carry out open loop correction after completing measurement.
In above-mentioned light path system, have employed annular diaphragm system, annular diaphragm and pupil face conjugation, thus realize the incident human eye of ring light in pupil face, simply and cleverly solve the problem of corneal reflex veiling glare, be conducive to the utilization of luminous energy power.
Whether the pupil monitoring camera in above-mentioned light path is used for observer's eye pupil hole good with Adaptable System optical axis alignment, also prepares for single calibration imaging and short exposure correcting imaging simultaneously.So-called single calibration, refers to and only carries out 1 to 2 detections to human eye aberration corrugated at short notice, and send a secondary correction corrugated afterwards, carry out single width imaging at CCD after Wavefront Rectification to pupil, flow chart is as Fig. 5.
Above-described embodiment is illustrative principle of the present utility model and effect thereof only, but not for limiting this utility model.Any person skilled in the art scholar all without prejudice under spirit of the present utility model and category, can modify above-described embodiment or changes.Therefore, such as have in art and usually know that the knowledgeable modifies or changes not departing from all equivalences completed under the spirit and technological thought that this utility model discloses, must be contained by claim of the present utility model.

Claims (7)

1. a Wearable pupillary light reflex measurement device, comprises nine key components:
Thermal camera, has data communication with data handling equipment, for obtaining the video data of human eye;
Infrared light compensating lamp, for providing illumination for thermal camera;
Supplementary lighting sources is visible light source, for simulating the illumination under different scene;
Stimulating light source is visible light source, produces varying aperture for irradiating pupil to make pupil;
The Wearable helmet, for installing the said equipment, for user eye provides dark room conditions;
Pupil correcting imaging system, comprises the optical path of liquid crystal corrector or distorting lens composition;
Whether pupil monitoring camera, aim at well with described pupil correcting imaging systematic optical axis, simultaneously for single calibration imaging and short exposure correcting imaging for observer's eye pupil hole;
Pupillometry software system, comprises physical size measuring system, physiologic information computing system and report preparing system, for detecting the pupil in video data in real time, obtaining the physiologic information that pupil is relevant, and generating case report, being configured in data handling equipment;
Data handling equipment, based on the personal computer of X86 or X64 framework, or has the embedded platform of equal disposal ability, removable handheld device.
2. Wearable pupillary light reflex measurement device as claimed in claim 1, is characterized in that: the data communication of thermal camera and data handling equipment is wire communication or wireless forms of communication; The quantity of thermal camera and stimulating light source is determined by the quantity of the pupil that will measure; The wavelength of its infrared light need mate the wavelength that adopted thermal camera can receive.
3. Wearable pupillary light reflex measurement device as claimed in claim 1, is characterized in that: described supplementary lighting sources is made up of the luminescent device that can send visible ray, produces the light of different illumination, different frequency according to demand; The luminous function of luminescent device is controlled by the pupillometry software system be configured in data handling equipment, or is controlled by independent by-pass cock.
4. Wearable pupillary light reflex measurement device as claimed in claim 1, is characterized in that: the luminance of described stimulating light source is controlled by the pupillometry software system be configured in data handling equipment, or is controlled by independent switch.
5. Wearable pupillary light reflex measurement device as claimed in claim 1, it is characterized in that: pupil correcting imaging Systematic selection liquid crystal corrector corrects mutually as the wavefront position of optical path, described pupil correcting imaging system comprises low order compensating glass, optical filter, half-wave plate, optical lens, polarization beam apparatus, location screen, annular diaphragm and wave front detector.
6. Wearable pupillary light reflex measurement device as claimed in claim 5, it is characterized in that: the described wave front detector of pupil correcting imaging system is high speed Hartmann sensor, pupil, liquid crystal corrector and Hartman wavefront detector Nonimage Conjugate Relations each other.
7. Wearable pupillary light reflex measurement device as claimed in claim 1, it is characterized in that: the visible physical arrangement of image data identification outward appearance wherein that the physical size measuring system in pupillometry software system is caught by infrared camera, and measure the size of often kind of structure.
CN201420784481.5U 2014-12-12 2014-12-12 A kind of Wearable pupillary light reflex measurement device Expired - Fee Related CN204723023U (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106333643A (en) * 2015-07-10 2017-01-18 中兴通讯股份有限公司 Monitor method, monitor device and monitor terminal for user health
CN108784643A (en) * 2018-05-28 2018-11-13 徐明娜 Pupillary light reflex measuring instrument after optic nerve injury
CN110251072A (en) * 2019-07-03 2019-09-20 深圳市龙华区中心医院 Pupil electronic observation device and pupil monitor system
CN113456013A (en) * 2021-07-13 2021-10-01 常州市第一人民医院 Automatic pupil monitor
CN113509138A (en) * 2021-05-11 2021-10-19 岭南师范学院 Laser self-mixing interference type autism child pupil light reflectometer

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106333643A (en) * 2015-07-10 2017-01-18 中兴通讯股份有限公司 Monitor method, monitor device and monitor terminal for user health
CN108784643A (en) * 2018-05-28 2018-11-13 徐明娜 Pupillary light reflex measuring instrument after optic nerve injury
CN110251072A (en) * 2019-07-03 2019-09-20 深圳市龙华区中心医院 Pupil electronic observation device and pupil monitor system
CN113509138A (en) * 2021-05-11 2021-10-19 岭南师范学院 Laser self-mixing interference type autism child pupil light reflectometer
CN113456013A (en) * 2021-07-13 2021-10-01 常州市第一人民医院 Automatic pupil monitor

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