CN204709072U - The biological 3D printing head of the many materials of Pneumatic-propelling that open valve is integrated - Google Patents
The biological 3D printing head of the many materials of Pneumatic-propelling that open valve is integrated Download PDFInfo
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- CN204709072U CN204709072U CN201520335842.2U CN201520335842U CN204709072U CN 204709072 U CN204709072 U CN 204709072U CN 201520335842 U CN201520335842 U CN 201520335842U CN 204709072 U CN204709072 U CN 204709072U
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Abstract
The utility model discloses the biological 3D printing head of the many materials of the integrated Pneumatic-propelling of a kind of open valve, comprise at least two group extrusion molding ejection head units, the structure often organizing extrusion molding ejection head unit is identical, comprises lower house, upper shell, spiral cover, piston, Compress Spring, barrel, open valve, quick connector and syringe needle.Multiple shower nozzle of the present utility model can control height of deposition with a motor and corresponding actuating device in vertical direction.And multiple ejection head unit utilizes the Pneumatic pressure itself extruded to drive the h that moves downward of ejection head unit intraware, the shower nozzle of work is selected from other shower nozzles.Like this, both avoided other shower nozzles to the interference of work forming face, also simplied system structure greatly, reduced costs.
Description
Technical field
This utility model relates to the biological 3D printing head of the many materials of the integrated Pneumatic-propelling of a kind of open valve, for Cell and organism file printing, belongs to tissue engineering technique and biological 3D printing field.
Background technology
For the treatment of impaired bulk soft tissue and internal organs, it is the very effective Therapeutic Method of one that human tissue organ transplants.But because the problems such as organ donor source shortage, immunologic rejection exist, there is the difficulty being difficult to overcome in organ transplantation treatment in practice.And the proposition of organizational project opens new approach for solving the problem.Organizational project be by living cells by conforming to someway on the support of biomaterial matrix or preparation, come constructing function tissue substituent.Then, after the tissue substituent of structure being carried out cultivating in patients with implantation body, replace original pathological tissues organ and realize disease treatment to recover physical function.The research of current organization engineering skin and use effective illustration with regard to the good development prospect of organizational project.
Tradition Tissue Engineering Study is limited to cell implanted prosthetics always, namely " is implanted on support by cell " in this organizational project inherent technology link, different types of Cell and organism material accurately cannot be navigated to internal stent different spatial.In fact, along with the propelling of Tissue Engineering Study, research work progressively prolongs life to bulk soft tissue and internal organs aspect, because these tissues and organ are often containing various kinds of cell and biomaterial, and different cell or material have specific spatial arrangement, therefore above-mentioned technical limitation highlights more.
In recent years, the fast development of 3D printing technique, for industry manufacture opens new manufacture production model.In biological field, the technology such as biometric print, cell three-dimensional controlled tissue are also applied and give birth to.These technology have the ability of operation individual cells or single composition microsize drop, can the accurately locus of control operation object and distribution, there is huge meaning for the locus deposition realizing Cell and organism material not of the same race in bulk tissue and organ building process.Therefore, the inexorable trend that biometric print technology is future organization engineering research is developed.And in a typical biometric print machine, one of critical component is exactly the shower nozzle that is shaped.
In order to the structure requirement of the various kinds of cell and material that meet bulk soft tissue and internal organs, need to develop a kind of many material formings shower nozzle.Many material formings shower nozzle generally adopts multiple shower nozzle to walk abreast and is arranged on sustained height, and each shower nozzle can process a kind of material or cell.Generally only having a shower nozzle in print procedure in work, just may there is the interference to structure texture forming face in other shower nozzles that sustained height is in shape of awaiting orders.For addressing this is that, Pu Xiang university of Korea S Dong-Woo Cho teaches many shower nozzles tissue/organ manufacture system (MtoBS) of team's exploitation, and the partly integrated 6 groups of shower nozzles of its shower nozzle, wherein 4 groups is pneumatic extrusion molding shower nozzle, 4 groups of position piston extrusion molding shower nozzles.In order to distinguish shower nozzle work and two states of awaiting orders, often organize shower nozzle and be equipped with a drive motors, by drive mechanism, the whole nozzle component namely participating in work is transferred to applicable height, utilize difference in height to separate with other armed state showerhead, can effectively avoid awaiting orders shower nozzle in print procedure to the situation of forming face interference.But too much owing to applying driving device, its system relative complex, cost is higher, and does not have extensibility (following process not only may be confined to cell and material in 6).
In order to distinguish two kinds of shower nozzle states of awaiting orders and work in guarantee, the situation that avoids interference occurs, simplifies its system structure simultaneously, and improve extensibility, this utility model provides a kind of propulsion type showerhead group structure based on extrusion pressure.
Summary of the invention
The technical solution of the utility model is as follows:
The biological 3D printing head of the many materials of the integrated Pneumatic-propelling of a kind of open valve comprises at least two group extrusion molding ejection head units, the structure often organizing extrusion molding ejection head unit is identical, comprise lower house, upper shell, spiral cover, piston, Compress Spring, barrel, open valve, quick connector and syringe needle, described upper shell and lower house are by screw compact siro spinning technology, and contact surface embedding sealing material seals; Described spiral cover is connected with upper shell by screw thread, for convenience detach, described piston is installed with lower house inner, described Compress Spring upper end contacts with piston lower surface, the bottom of described barrel is arranged on internal piston, the top of described barrel is arranged on upper shell inside, and described open valve and quick connector are arranged on upper shell, and syringe needle is arranged on the bottom of barrel.
Preferably, described piston can carry out sliding motion in lower house inside, installs sealing ring and realize sealing between piston and lower house; Described Compress Spring upper end contacts with piston lower surface, and Compress Spring bottom contacts with lower house, and spring is in compressive state; The lower surface of described upper shell can be ejected by Compress Spring by limit slip piston.
Preferably, described barrel bottom is arranged on internal piston, coaxially installs, is fixed together with sliding piston, can with piston sliding motion; Described barrel top is arranged on upper shell inside, and contact surface utilizes sealing ring to seal, between the two can relative sliding.
Preferably, described open valve comprises valve body, valve pocket, spool, Mini compressed spring and sealing ring; Described valve pocket has axial valve port A and radial valve port B; Described valve body and valve pocket are installed together, interference fit; Spool is arranged in valve pocket, good seal between spool and valve pocket, and spool can slippage in valve pocket inside; Described Mini compressed spring fitting is between valve body and spool, and Mini compressed spring is in compressive state all the time, and under Mini compressed spring action, spool and valve pocket compress, and valve port A's and B is separated.
Preferably, between the valve pocket of described open valve and upper shell, sealing ring is housed, ensures contact surface good seal; Can adopt between valve body with upper shell and be threaded, good seal.
Preferably, valve port A is directly communicated with quick connector by runner X and Y.
Preferably, described piston adopts ledge structure, there is a cavity a between described upper shell, lower house, piston, barrel all the time; Described cavity a directly communicates with quick connector by flowing to X.
Preferably, form a cavity b between described upper shell, valve body, valve pocket, described upper shell, between barrel and spiral cover, form cavity c; Described cavity c and cavity b is by runner UNICOM.
Preferably, described syringe needle can be syringe needle, also can be dispensing needle head.
Multiple shower nozzle of the present utility model can control height of deposition with a motor and corresponding actuating device in vertical direction.And multiple ejection head unit utilizes the Pneumatic pressure itself extruded to drive the h that moves downward of ejection head unit intraware, the shower nozzle of work is selected from other shower nozzles.Like this, both avoided other shower nozzles to the interference of work forming face, also simplied system structure greatly, reduced costs;
Power gas source and pressure switch (open valve) are integrated on housing, connect in use just need not do to connect and adjust once loop again; And only need take off spiral cover in loading printing solution processes, move into and print liquid; Make more convenient to operate like this, fast, to the ability also too large requirement useless of user.
By changing the open valve of different size, different work extrusion pressure P3 can be obtained, be applicable to the printing of different occasion and different materials; Open valve is changed convenient, need not change the overall structure of shower nozzle, substantially increase its expanded application ability.
Accompanying drawing explanation
Fig. 1 is the structural representation of the biological 3D printing head of the many materials of 3 × 2 form Pneumatic-propelling;
Fig. 2 is the many materials of 3 × 2 form Pneumatic-propelling biological 3D printing head front view;
Fig. 3 is the many materials of 3 × 2 form Pneumatic-propelling biological 3D printing head top view;
Fig. 4 is that the ejection head unit structure A-A of the biological 3D printing head of the many materials of Pneumatic-propelling is to full sectional view;
Fig. 5 is the many materials of Pneumatic-propelling biological 3D printing head unit piston place partial enlarged drawing;
Fig. 6 is that the many materials of Pneumatic-propelling biological 3D printing head cellular construction B-B is to phantom;
Fig. 7 is open valve complete section schematic diagram;
Fig. 8 is the two states of ejection head unit: left hand view is armed state (the first ejection head unit 1 and 3), and right side is duty (the 5th ejection head unit 5).
Detailed description of the invention
Concrete structure of the present utility model, operation principle and work process content is further illustrated below in conjunction with drawings and Examples.
This utility model designs the biological 3D printing head of the many materials of the integrated Pneumatic-propelling of a kind of open valve, at least comprises two extrusion molding ejection head units.This utility model explains with the jet head sets of 3 × 2 forms of Fig. 1, comprises the first extrusion molding ejection head unit 1, second extrusion molding ejection head unit 2, the 3rd extrusion molding ejection head unit 3, the 4th extrusion molding ejection head unit 4, the 5th extrusion molding ejection head unit 5 and the 6th extrusion molding ejection head unit 6.
Each extrusion molding ejection head unit housing parts comprises upper shell 8 and lower house 7, and both can be connected by screw, and contact surface is lined with encapsulant, good seal; Spiral cover 9 is threaded connection mode and is arranged on spiral cover 8, can freely take off or change.
Lower house 7 inside is provided with piston 10, and piston 10 can slide up and down along lower house inner cylinder wall, and the contact surface sealing ring 16 between piston 10 and lower house 7 seals; Compress Spring 11 is arranged between lower house 7 and piston 10, and spring 11 is in compressive state all the time, acts on lower piston 10 be in maximum displacement place at spring 11, i.e. the upper surface of piston 10 and upper shell 8; Piston 10 adopts ledge structure, when piston 10 is in maximum displacement place, only have the crowning 101 of piston to contact with the bottom surface of upper shell 8, piston 10, upper shell 8, between barrel 12 and lower house 7, form cavity a, no matter where piston is in, and cavity a exists all the time; Barrel 12 and piston 10 are fixed together, and can move up and down, be provided with syringe needle 15 below with piston 10, and syringe needle 15 can be injection needle also can be self-control syringe needle.
Upper shell 8 is provided with quick connector 14, is threaded connection, for inputting hose connection with source of the gas, quick connector 14 can adopt different size according to actual hose outside diameter; Upper shell 14 processes a runner X, quick connector 14 is coupled together with cavity a.
Upper shell 8 is provided with open valve 13, open valve 13 is connected with female thread on upper shell 8 by screw thread 181, junction good seal; Upper shell 8 is processed with runner Y, by runner X with Y, quick connector 14 is connected with the valve port B of open valve 13.
Open valve 13 structure comprises valve body 18, sealing ring 22, spool 20 and Mini compressed spring 21; It is inner that valve pocket 22 is arranged on valve body 18, and both are without relative motion, contact surface good seal; It is inner that spool 20 is arranged on valve pocket 22, can slide up and down, good seal between spool 20 and valve pocket 22 along valve pocket 22 inwall; Mini compressed spring 21 is arranged between valve body 18 and spool 20, is in compressive state all the time; Valve pocket 22 there is valve port A and B, when original state bottom spool is positioned at bottom, make valve port A and B disconnect; Valve pocket 19 on open valve 13 seals with the contact surface sealing ring 22 of upper shell 8.
Utility model works principle:
Before printing, cell and biomaterial solution are installed in barrel 12.Under original state, under Compress Spring 11 acts on, sliding piston 10 is in top, and all extrusion molding ejection head units are in same state, and therefore syringe needle 15 top is positioned at sustained height; Under Mini compressed spring 21 acts on, in open valve 13, valve port A and B is in off-state.
Load and print solution:
Taken off by spiral cover 9, utilization moves liquid instrument and deployed biological solution is loaded into barrel 12 inside, is advisable be no more than barrel 12 height 2/3; Move liquid complete good, load onto spiral cover 9, confirm to tighten.
Pneumatic line connects:
The gas produced by air pump, through air supply processing equipment, is connected with quick connector 14 through the flexible pipe of external diameter 6mm after the process such as control valve, confirms that loop seals is good, without leaking phenomenon.
Power classification inputs:
Regulate proportional valve control input pressure to enter a certain extrusion molding ejection head unit inside (as extrusion molding ejection head unit 5) needing work, gas enters cavity a by quick connector 12 through runner X; Maintain and regulate input pressure to be P1, also air pressure P1 is stablized in acquisition at cavity a; The active force that air pressure P1 produces at piston 10 upper surface overcomes spring 11 elastic force, promotes piston 10 slippage downwards to maximum position; Barrel 12(is containing house print solution) and syringe needle 15 and piston 10 link together, with piston 10 decline phase co-altitude; Maximum height difference is h.
The difference in height utilizing work extrusion molding ejection head unit 5 to decline is by itself and other armed state extrusion molding ejection head unit (1,2,3,4 and 6) distinguish, avoid armed state extrusion molding ejection head unit (1,2,3,4 and 6) interference and destruction forming face in motor process.
At this moment, input gas also produces air pressure P1 by runner X and Y at valve port A place, and the active force produced bottom open valve 13 spool 20 due to P1 is less than Mini compressed spring 21 active force, and valve port A closes, and cavity b and coupled cavity c still maintains normal pressure.
Passing ratio valve improves input pressure further, when pressure increase is to P2(P2>P1) time, the active force that P2 produces bottom the spool 20 of open valve 13 can overcome the effect of Mini compressed spring 21, promotes spool and moves upward; This is that valve port A and B UNICOM, gas enters cavity b, and is entered by runner in the cavity c be connected with cavity b.
Maintain or continue to improve input pressure, air pressure P3(P3 >=P2 is produced in barrel 12), the upper surface of the printing solution of pressure P 3 in barrel 12 produces active force, promotes to print solution and extrudes in syringe needle, deposit to profiled surface, for building histoorgan structure.
By the effective pressure active area of the rigidity of spring 11, sliding assembly, quality and coefficient of friction, can balance elastic force, gravity, relation between frictional force and pressure, the pressure P 1 that can obtain different size is worth
By changing the open valve 13 of different size, different work extrusion pressure P3 can be obtained, be applicable to the printing of different occasion and different materials;
When printing complete, passing ratio valve reduces or opening pressure input, cavity a, air pressure in b and c recovers normal pressure, act on bottom spool 21 at Mini compressed spring 21 to move downward valve port A and B is disconnected, simultaneously under Compress Spring 11 acts on, piston 10 moves upward to maximum displacement place, drive syringe needle 15 to bounce back, whole nozzle component 5 returns to original state.
Whole jet head sets is arranged in three-dimensional movement platform, and drive jet head sets to move by three-dimensional motion, locus and the motion path of shower nozzle are controlled by three-dimensional movement platform.
Advantage of the present utility model:
Multiple shower nozzle of the present utility model can control height of deposition with a motor and corresponding actuating device in vertical direction.And multiple ejection head unit utilizes the Pneumatic pressure itself extruded to drive the h that moves downward of ejection head unit intraware, the shower nozzle of work is selected from other shower nozzles.Like this, both avoided other shower nozzles to the interference of work forming face, also simplied system structure greatly, reduced costs;
Power gas source and pressure switch (open valve) are integrated on housing, connect in use just need not do to connect and adjust once loop again; And only need take off spiral cover in loading printing solution processes, move into and print liquid; Make more convenient to operate like this, fast, to the ability also too large requirement useless of user.
By changing the open valve of different size, different work extrusion pressure P3 can be obtained, be applicable to the printing of different occasion and different materials; Open valve is changed convenient, need not change the overall structure of shower nozzle, substantially increase its expanded application ability.
Claims (9)
1. the biological 3D printing head of the many materials of Pneumatic-propelling that an open valve is integrated, it is characterized in that comprising at least two group extrusion molding ejection head units, the structure often organizing extrusion molding ejection head unit is identical, comprise lower house, upper shell, spiral cover, piston, Compress Spring, barrel, open valve, quick connector and syringe needle, described upper shell and lower house are by screw compact siro spinning technology, and contact surface embedding sealing material seals; Described spiral cover is connected with upper shell by screw thread, for convenience detach, described piston is installed with lower house inner, described Compress Spring upper end contacts with piston lower surface, the bottom of described barrel is arranged on internal piston, the top of described barrel is arranged on upper shell inside, and described open valve and quick connector are arranged on upper shell, and syringe needle is arranged on the bottom of barrel.
2. the biological 3D printing head of the many materials of the Pneumatic-propelling that a kind of open valve as claimed in claim 1 is integrated, is characterized in that: described piston can carry out sliding motion in lower house inside, installs sealing ring and realize sealing between piston and lower house; Described Compress Spring upper end contacts with piston lower surface, and Compress Spring bottom contacts with lower house, and spring is in compressive state; The lower surface of described upper shell can be ejected by Compress Spring by limit slip piston.
3. the biological 3D printing head of the many materials of the Pneumatic-propelling that a kind of open valve as claimed in claim 1 or 2 is integrated, it is characterized in that: described barrel bottom is arranged on internal piston, coaxial installation, is fixed together with sliding piston, can with piston sliding motion; Described barrel top is arranged on upper shell inside, and contact surface utilizes sealing ring to seal, between the two can relative sliding.
4. the biological 3D printing head of the many materials of the Pneumatic-propelling that a kind of open valve as claimed in claim 1 is integrated, is characterized in that: described open valve comprises valve body, valve pocket, spool, Mini compressed spring and sealing ring; Described valve pocket has axial valve port A and radial valve port B; Described valve body and valve pocket are installed together, interference fit; Spool is arranged in valve pocket, good seal between spool and valve pocket, and spool can slippage in valve pocket inside; Described Mini compressed spring fitting is between valve body and spool, and Mini compressed spring is in compressive state all the time, and under Mini compressed spring action, spool and valve pocket compress, and valve port A's and B is separated.
5. the biological 3D printing head of the many materials of Pneumatic-propelling that a kind of open valve as described in claim 1 or 4 is integrated, is characterized in that: between the valve pocket of described open valve and upper shell, sealing ring is housed, ensures contact surface good seal; Adopt between valve body with upper shell and be threaded, good seal.
6. the biological 3D printing head of the many materials of the Pneumatic-propelling that a kind of open valve as claimed in claim 5 is integrated, is characterized in that: valve port A is directly communicated with quick connector by runner X and Y.
7. the biological 3D printing head of the many materials of the Pneumatic-propelling that a kind of open valve as claimed in claim 1 is integrated, is characterized in that: described piston adopts ledge structure, there is a cavity a between described upper shell, lower house, piston, barrel all the time; Described cavity a directly communicates with quick connector by flowing to X.
8. the biological 3D printing head of the many material of the Pneumatic-propelling that a kind of open valve as claimed in claim 1 is integrated, is characterized in that: form a cavity b between described upper shell, valve body, valve pocket, described upper shell, forms cavity c between barrel and spiral cover; Described cavity c and cavity b is by runner UNICOM.
9. the biological 3D printing head of the many materials of the Pneumatic-propelling that a kind of open valve as claimed in claim 1 is integrated, is characterized in that: described syringe needle is syringe needle or dispensing needle head.
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| CN201520335842.2U CN204709072U (en) | 2015-05-22 | 2015-05-22 | The biological 3D printing head of the many materials of Pneumatic-propelling that open valve is integrated |
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| CN201520335842.2U CN204709072U (en) | 2015-05-22 | 2015-05-22 | The biological 3D printing head of the many materials of Pneumatic-propelling that open valve is integrated |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104827672A (en) * | 2015-05-22 | 2015-08-12 | 杭州汉卓机电科技有限公司 | Opening valve integrated pneumatic push type multi-material biological 3D printing nozzle |
| CN106388970A (en) * | 2016-11-02 | 2017-02-15 | 周惠兴 | Shower nozzle device with parcel function |
| CN113524659A (en) * | 2021-07-14 | 2021-10-22 | 北京航空航天大学 | Method for manufacturing micro-structure conical needle |
| CN113786955A (en) * | 2021-07-19 | 2021-12-14 | 浙江欣世纪建筑系统科技有限公司 | Automatic gluing equipment and process for glass curtain wall frame |
-
2015
- 2015-05-22 CN CN201520335842.2U patent/CN204709072U/en active Active
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104827672A (en) * | 2015-05-22 | 2015-08-12 | 杭州汉卓机电科技有限公司 | Opening valve integrated pneumatic push type multi-material biological 3D printing nozzle |
| CN106388970A (en) * | 2016-11-02 | 2017-02-15 | 周惠兴 | Shower nozzle device with parcel function |
| CN106388970B (en) * | 2016-11-02 | 2018-04-13 | 四川蓝光英诺生物科技股份有限公司 | A kind of ejecting device with parcel |
| CN113524659A (en) * | 2021-07-14 | 2021-10-22 | 北京航空航天大学 | Method for manufacturing micro-structure conical needle |
| CN113786955A (en) * | 2021-07-19 | 2021-12-14 | 浙江欣世纪建筑系统科技有限公司 | Automatic gluing equipment and process for glass curtain wall frame |
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