CN204556808U - A kind of preamplifier for nuclear magnetic resonance spectrometer or imager - Google Patents

A kind of preamplifier for nuclear magnetic resonance spectrometer or imager Download PDF

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Publication number
CN204556808U
CN204556808U CN201520282487.7U CN201520282487U CN204556808U CN 204556808 U CN204556808 U CN 204556808U CN 201520282487 U CN201520282487 U CN 201520282487U CN 204556808 U CN204556808 U CN 204556808U
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Prior art keywords
prime amplifier
signal
imager
system bus
nuclear magnetic
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CN201520282487.7U
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李晶晶
李正刚
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WUHAN ZHONGKE NIUJIN WAVE SPECTRUM TECHNOLOGY Co.,Ltd.
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WUHAN ZHONGKE MAGNETIC RESONANCE TECHNOLOGY Co Ltd
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Abstract

The utility model discloses a kind of preamplifier for nuclear magnetic resonance spectrometer or imager, the system bus comprising multiple prime amplifier and be jointly connected with multiple prime amplifier, wherein, each prime amplifier includes the first wave filter, high-power quick transceiver toggle switch, quatrter-wavelength line, the second wave filter, bidirectional oriented coupling mechanism, detection module, low noise amplifier and the frequency mixer that coupling is mutually arranged; System bus is all identical with the connecting interface of each prime amplifier, and system bus is for adjusting the high-power quick transceiver toggle switch state in each prime amplifier, thus plays the effect of adjustment preamplification signal output.The utility model is equipped with bidirectional coupler and power detector due to each prime amplifier, can transship to probe signal, load mismatch warning function and load tuning, guarantee that prime amplifier works in safe condition.

Description

A kind of preamplifier for nuclear magnetic resonance spectrometer or imager
Technical field
The utility model belongs to nuclear magnetic resonance apparatus field, more specifically, relates to a kind of preamplifier for nuclear magnetic resonance spectrometer or imager.
Background technology
Nuclear magnetic resonance apparatus is the development and production of using NMR principle, it is by launching high power pulse signal excitation testee nuclear resonance effect to testee, and measures the feeble signal that nuclear macroscopic magnetization vector produces in nuclear magnetic resonance apparatus receiving coil and obtain testee information thus.Because the information in receiving coil is faint, therefore prime amplifier must be used.In nuclear magnetic resonance spectrometer or imager, high power pulse signal and faint NMR signal need timesharing to pass through prime amplifier, prime amplifier will complete the switching over of the faint NMR signal of launching highpowerpulse signal and reception, accomplish that both do not interfere with each other by signal, and feeble signal is needed to provide enough gains and very low noise figure.In addition, prime amplifier also needs NMR signal to carry out down-converted, to carry out digitized processing.
In order to obtain good measurement effect, nuclear magnetic resonance spectrometer and imager all need to use several to dozens of prime amplifiers, and detect or the parallel object received to realize multiple atomic nucleus, all prime amplifiers all need unified co-ordination.The nuclear magnetic resonance spectrometer prime amplifier that open source literature both domestic and external and patent are mentioned all only relates to each passage low noise amplification part, and launch, duty detecting portion, lack the research of the aspects such as the topology layout of prime amplifier and amplified signal process.Specifically, prior art all uses a controller to control multiple prime amplifier, as shown in Figure 1,3.Communication controller 101, logic controller 102 form the controller of prime amplifier jointly, and its external interface comprises power interface, communication interface, gate-control signal interface; Controller export many groups control cable 1004,1005 ... 100n, is connected to each prime amplifier respectively, the signal transmitted in cable comprise power supply, logic control signal etc.Such as, prior art document (such as patent documentation US7123090B2, US5545999, CN200920181229.4, CN201020127030.6 etc.) (namely the method that uses be above-mentioned use controller, communication controller 101, the controller of the common composition prime amplifier of logic controller 102) method that multiple prime amplifier is controlled, its shortcoming of prime amplifier of adopting in this way is: the output pin quantity 1) being limited to controller, cause can the prime amplifier limited amount of supporting setting, make this prime amplifier can only be applied to the occasion only needing a small amount of prime amplifier, on the other hand, in the actual use of nuclear magnetic resonance spectrometer and imager, the quantity of prime amplifier is not often certain, but need the quantity of adding arbitrarily prime amplifier according to user demand, increase any prime amplifier on the original basis all to need to unify amendment to the working method of prime amplifier, this technology cannot adapt to the demand increasing arbitrarily or cancel prime amplifier quantity as required,
2) because each prime amplifier exists difference, of all kinds for the control cable connecting each prime amplifier, be difficult to unified, for mass production adds difficulty.
Utility model content
For above defect or the Improvement requirement of prior art, the purpose of this utility model is to provide a kind of preamplifier for nuclear magnetic resonance spectrometer or imager, wherein by improving in internal structure and set-up mode etc. the prime amplifier of its key and supporting system bus etc. thereof, compared with prior art effectively can solve the problem that system line cable is complicated, increase and decrease prime amplifier difficulty, and prime amplifier can provide enough gains and very low noise figure, enlarge leadingly effective.
For achieving the above object, according to the utility model, provide a kind of preamplifier for nuclear magnetic resonance spectrometer or imager, it is characterized in that, the system bus that this preamplifier comprises multiple prime amplifier and is jointly connected with described multiple prime amplifier, wherein:
Prime amplifier described in each includes the first wave filter, high-power quick transceiver toggle switch, quatrter-wavelength line, the second wave filter, bidirectional oriented coupling mechanism, low noise amplifier and the frequency mixer that coupling is mutually arranged; Wherein, this first wave filter is connected with described high-power quick transceiver toggle switch, for the PA signal of input nucleus resonance spectrometer or imager; This high-power quick transceiver toggle switch is connected with described bidirectional oriented coupling mechanism by described second wave filter, for launching above-mentioned PA signal to the probe of nuclear magnetic resonance spectrometer or imager; In addition, this bidirectional oriented coupling mechanism is connected with described frequency mixer with described low noise amplifier by described second wave filter, described high-power quick transceiver toggle switch, described quatrter-wavelength line successively, for receiving the signal from described probe, and the signal from described probe is amplified and Frequency mixing processing to obtain preamplification signal, and export this preamplification signal to nuclear magnetic resonance spectrometer or imager;
Described system bus is all identical with the connecting interface described in each between prime amplifier, and this system bus is then for performing blocked operation to the described high-power quick transceiver toggle switch in prime amplifier described in each, thus plays the effect of the described preamplification signal output of adjustment.
As of the present utility model preferred further, described in each, prime amplifier all also comprises controller, and this controller is connected with described system bus, for adjusting the output of prime amplifier preamplification signal described in each.
As of the present utility model preferred further, prime amplifier described in each all also comprises detection module, this detection module is connected with described bidirectional oriented coupling mechanism, and for monitoring the signal from described probe, and it is tuning to carry out load according to the signal from described probe.
As of the present utility model preferred further, this preamplifier also comprises display, and described display is connected with described system bus, for showing the duty of prime amplifier described in each.
As of the present utility model preferred further, described system bus communicates with using SPI described in each between prime amplifier.
By the above technical scheme that the utility model is conceived, compared with prior art, there is following beneficial effect:
1. each prime amplifier is provided with bidirectional coupler and power detector, bidirectional coupler is connected with power detector, realize the amplitude detection process of forward signal between prime amplifier and load and reflected signal, can settling signal overload, load mismatch warning function and load tuning, guarantee that prime amplifier works in safe condition.
In addition, by system bus is connected with display, the duty of each prime amplifier, tuning state and alarm condition etc. can be shown in real time, realize the omnibearing monitoring of preamplifier.
2. when many prime amplifiers are combined, the interface that each prime amplifier is connected with system bus is completely the same, each prime amplifier controls separately by unified interface, the quantity of prime amplifier can unrestrictedly be expanded, and according to actual needs, the prime amplifier of any amount is installed, and without the need to making any amendment to original system.
Compared with the cable used with prior art, the system bus in the utility model is very simple, and the expansion of prime amplifier quantity, no longer by the restriction of number of cables, can realize adding arbitrarily as required or deleting, and not have an impact to existing system.
Accompanying drawing explanation
Fig. 1 is logic controller in background technology, the connection diagram controlling cable and each prime amplifier;
Fig. 2 is the connection diagram of the utility model central controller, system bus and each prime amplifier;
Fig. 3 is preamplifier structural representation in background technology;
Fig. 4 is the structural representation of the utility model preamplifier;
Fig. 5 is the inner structure schematic diagram of the utility model prime amplifier.
In Fig. 1-5, the implication of Reference numeral is as follows: 101 is communication controller; 102 is logic controller; 1004,1005 ... 100n is control cable; 104,105 ... 10n is prime amplifier;
201 is TFT display; 202 is central controller; 203 is system bus; 204,205 ... 20n is prime amplifier;
11 is wave filter; 12 is high-power quick transceiver toggle switch; 13 is quatrter-wavelength line; 14 is wave filter; 15 is bidirectional oriented coupling mechanism; 16 is detection module; 17 is low noise amplifier; 18 is frequency mixer; 19 is prime amplifier controller.
Embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the utility model is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the utility model, and be not used in restriction the utility model.In addition, if below in described each embodiment of the utility model involved technical characteristic do not form conflict each other and just can mutually combine.
Embodiment 1
The preamplifier architectures that the utility model proposes as shown in Figure 4.Pre-amplifier system is made up of central controller, display and multiple prime amplifier.
Fig. 1,2 is background technology and control linkage cable signal figure of the present utility model.Form different from background technology controller by communication controller 101 and logic controller 102, controller of the present utility model only has central controller 202, it completes the communication interaction with external system (other parts of such as nuclear magnetic resonance spectrometer or imager), and Content of Communication is distributed to control by central controller 202 prime amplifier 204,205 ... the controller 19 of 20n.
Central controller 202 is only provided with a prime amplifier control interface, is connected with system bus 203, and system bus 203 is provided with multiple connector, prime amplifier 204,205 ... 20n is parallel on system bus 203.
A prime amplifier needs one to launch gate-control signal and a reception gate-control signal, for controlling the sequential logic of all parts work.In prior art, for control each prime amplifier 104,105 ... gate-control signal is launched on (n-3) road of 10n and (n-3) road receives gate-control signal by outside input logic controller 102, (n-3) road is launched gate-control signal and (n-3) road and is received gate-control signal and be converted to corresponding control signal by logic controller 102, and through control cable 1004,1005 ... the cable set be connected with corresponding prime amplifier in 100n exports.
Prime amplifier 104 of the prior art, 105 ... the demand for control of 10n is not from identical, logic controller 102 need according to prime amplifier 104,105 ... 10n demand for control separately customizes its control signal, control signal be directly used in prime amplifier 104,105 ... the control of each functional part of 10n.Except power lead 7.5V, 15V and ground wire GND, prime amplifier 104,105 ... the control signal of 10n is different, correspond to control cable 1004,1005 ... 100n, the quantity controlling control signal wire in cable is not from several to tens etc.
As shown in Figure 2, the utility model adopts distributed control method, central controller 202 and prime amplifier 204, 205, a system bus 203 is used to connect between 20n, system bus 203 is except transmission power supply 7.5V, outside 15V and ground GND, only have a limited number of several communications control signal line: SCLK, CS, DI, DO, prime amplifier 204, 205, the interface of 20n is identical, each prime amplifier 204, 205, 20n is connected in parallel on system bus 203, the controller 19 of each prime amplifier inside receives corresponding communication control commands by mailing address mark, complete the control of each prime amplifier duty.
Compared with the control cable used with background technology, the utility model system bus is very simple, and the expansion of prime amplifier quantity, no longer by the restriction of number of cables, can realize adding arbitrarily as required or deleting, and not have an impact to existing system.
Background technology generally uses the serial communication technologies such as RS232, RS485 to control prime amplifier, central controller 202 of the present utility model uses CAN to communicate with outside, compared with the serial communication technologies such as RS232, RS485, CAN has its significant advantage: transfer rate is high, communication automatic Verification, multi-node communication, security are high, make the pre-amplifier system that the utility model proposes directly can access nuclear magnetic resonance spectrometer or the imager of existing use CAN, and control mode is simpler.
Central controller 202, except each prime amplifier work of control, is also responsible for duty and the alarm condition of each prime amplifier, and is used TFT display 201 to show.
Prime amplifier needs to carry out tuning work to respective load, background technology uses the values for tuning of mode to load such as charactron, LED composition lines to show, cannot aware load be in the tuning situation of each Frequency point intuitively, when tuning offset is very large, displayed value does not have reference significance substantially.The utility model then uses TFT display to replace, and directly show the tuning curve of each prime amplifier load, user more intuitive and convenient can judge the tuning situation of load.
Figure 5 shows that preamplifier architectures figure of the present utility model.Prime amplifier forms by launching, receiving, control 3 funtion parts:
1) wave filter 11, high-power quick transceiver toggle switch 12, quatrter-wavelength line 13, wave filter 14, bidirectional oriented coupling mechanism 15 form the emission function part of prime amplifier.
2) bidirectional oriented coupling mechanism 15, wave filter 14, quatrter-wavelength line 13, high-power quick transceiver toggle switch 12, low noise amplifier 17, frequency mixer 18 form the receiving function part of prime amplifier.
3) prime amplifier controller 19 outside is connected with system bus 203, receives the control command of central controller 202, and uploads the duty of prime amplifier to central controller 202.Prime amplifier controller 19 completes power supply, the logic control of all functions parts in prime amplifier, makes prime amplifier complete the work of specifying by instruction.
Bidirectional oriented coupling mechanism 15, wave filter 14, quatrter-wavelength line 13 and high-power quick transceiver toggle switch 12 time-sharing multiplex act on the faint nuclear magnetic signal of high-power RF signal transmitting and receiving;
Wave filter 11 and wave filter 14 are hindered the various models such as wave filter formed by bandpass filter, low-pass filter, with, can according to the flexible option and installment of the demand of each prime amplifier.
High-power quick transceiver toggle switch 12 is made up of with quatrter-wavelength line 13 PIN diode, under control of the controller 19, is switched to by prime amplifier transmission channel to open or receiving cable opening.
Low noise amplifier 17 is made up of first order low noise amplification chip and the integrated amplification chip of second level fixed gain, realizes the low noise amplification of prime amplifier.
Bidirectional coupler 15 and detection module 16 combine the amplitude detection process of forward signal and the reflected signal realized between prime amplifier and load, can settling signal overload, load mismatch warning function and load tuning, guarantee that prime amplifier works in safe condition.
The signal received is carried out down coversion by frequency mixer 18, and its input end is provided with switch selectable and selects multiple input, except completing the process of prime amplifier own module, can also input the signal of other modules, to reduce system cost.
Controller 19 provides power supply for each functional module of prime amplifier, and press the input command of central controller 202, with the transmitting gate of external system input, the work of reception gate control prime amplifier, the duty of all parts is uploaded to central controller 202 simultaneously, makes the duty of prime amplifier be in controlled, visibility status.
Each prime amplifier adopts Modular Structure Design, and each prime amplifier is an independent module, and in module, topological design is identical.The module that each prime amplifier self composition one is independent, interface, the structure of each prime amplifier are identical, only there is minute differences in internal circuit parameter, modular design decreases mutual interference between each module and coupling, also achieve the decline of prime amplifier processing cost, the consistance of physical construction make original prime amplifier 204,205 ... the basis of 20n directly can increase pre-amplifier module.Prime amplifier meets the user demand of nuclear magnetic resonance spectrometer and imager by the combination of any amount, in use also can increase at any time or delete prime amplifier quantity, not needing to carry out any amendment to existing system.
Those skilled in the art will readily understand; the foregoing is only preferred embodiment of the present utility model; not in order to limit the utility model; all do within spirit of the present utility model and principle any amendment, equivalent to replace and improvement etc., all should be included within protection domain of the present utility model.

Claims (5)

1., for a preamplifier for nuclear magnetic resonance spectrometer or imager, it is characterized in that, the system bus (203) that this preamplifier comprises multiple prime amplifier and is jointly connected with described multiple prime amplifier, wherein:
Prime amplifier described in each includes the first wave filter (11), high-power quick transceiver toggle switch (12), quatrter-wavelength line (13), the second wave filter (14), bidirectional oriented coupling mechanism (15), low noise amplifier (17) and the frequency mixer (18) that coupling is mutually arranged; Wherein, this first wave filter (11) is connected with described high-power quick transceiver toggle switch (12), for the PA signal of input nucleus resonance spectrometer or imager; This high-power quick transceiver toggle switch (12) is connected with described bidirectional oriented coupling mechanism (15), for launching above-mentioned PA signal to the probe of nuclear magnetic resonance spectrometer or imager by described second wave filter (14); In addition, this bidirectional oriented coupling mechanism (15) is connected with described frequency mixer (18) with described low noise amplifier (17) by described second wave filter (14), described high-power quick transceiver toggle switch (12), described quatrter-wavelength line (13) successively, for receiving the signal from described probe, and the signal from described probe is amplified and Frequency mixing processing to obtain preamplification signal, and export this preamplification signal to nuclear magnetic resonance spectrometer or imager;
Described system bus (203) is all identical with the connecting interface described in each between prime amplifier, and this system bus (203) is then for performing blocked operation to the described high-power quick transceiver toggle switch (12) in prime amplifier described in each, thus plays the effect of the described preamplification signal output of adjustment.
2. as claimed in claim 1 for the preamplifier of nuclear magnetic resonance spectrometer or imager, it is characterized in that, prime amplifier described in each all also comprises controller (19), this controller (19) is connected with described system bus (203), for adjusting the output of prime amplifier preamplification signal described in each.
3. as claimed in claim 1 for the preamplifier of nuclear magnetic resonance spectrometer or imager, it is characterized in that, prime amplifier described in each all also comprises detection module (16), this detection module (16) is connected with described bidirectional oriented coupling mechanism (15), for monitoring the signal from described probe, and it is tuning to carry out load according to the signal from described probe.
4. as claimed in claim 1 for the preamplifier of nuclear magnetic resonance spectrometer or imager, it is characterized in that, this preamplifier also comprises display (201), described display (201) is connected with described system bus (203), for showing the duty of prime amplifier described in each.
5., as claimed in claim 1 for the preamplifier of nuclear magnetic resonance spectrometer or imager, it is characterized in that, described system bus (203) communicates with using SPI described in each between prime amplifier.
CN201520282487.7U 2015-05-01 2015-05-01 A kind of preamplifier for nuclear magnetic resonance spectrometer or imager Active CN204556808U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022121417A1 (en) * 2020-12-07 2022-06-16 武汉联影生命科学仪器有限公司 Tuning and matching apparatus and method, magnetic resonance imaging device, and display interaction apparatus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022121417A1 (en) * 2020-12-07 2022-06-16 武汉联影生命科学仪器有限公司 Tuning and matching apparatus and method, magnetic resonance imaging device, and display interaction apparatus

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Address after: No.128, Guanggu 7th Road, Donghu hi tech Development Zone, Wuhan City, Hubei Province, 430075

Patentee after: WUHAN ZHONGKE NIUJIN WAVE SPECTRUM TECHNOLOGY Co.,Ltd.

Address before: 430075 No.128, Guanggu 7th Road, Donghu New Technology Development Zone, Wuhan City, Hubei Province

Patentee before: WUHAN ZHONGKE MR TECHNOLOGY Co.,Ltd.