CN204550562U - The strainer of tumour cell and single unit system in a kind of separating blood fluid - Google Patents
The strainer of tumour cell and single unit system in a kind of separating blood fluid Download PDFInfo
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- CN204550562U CN204550562U CN201520192754.1U CN201520192754U CN204550562U CN 204550562 U CN204550562 U CN 204550562U CN 201520192754 U CN201520192754 U CN 201520192754U CN 204550562 U CN204550562 U CN 204550562U
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- 239000012530 fluid Substances 0.000 title claims abstract description 31
- 210000004369 blood Anatomy 0.000 title claims abstract description 18
- 239000008280 blood Substances 0.000 title claims abstract description 18
- 210000004881 tumor cell Anatomy 0.000 title claims abstract description 17
- 238000001914 filtration Methods 0.000 claims abstract description 25
- 238000005530 etching Methods 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 9
- 238000007710 freezing Methods 0.000 claims description 14
- 239000007924 injection Substances 0.000 claims description 8
- 238000002347 injection Methods 0.000 claims description 8
- 239000005557 antagonist Substances 0.000 claims description 7
- 239000002504 physiological saline solution Substances 0.000 claims description 7
- 230000004087 circulation Effects 0.000 claims description 6
- 230000002572 peristaltic effect Effects 0.000 claims description 3
- 238000003466 welding Methods 0.000 claims description 2
- 239000012528 membrane Substances 0.000 abstract description 7
- 241001465754 Metazoa Species 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 230000001225 therapeutic effect Effects 0.000 abstract description 2
- 239000007788 liquid Substances 0.000 description 15
- 230000001413 cellular effect Effects 0.000 description 10
- 238000000034 method Methods 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 238000012545 processing Methods 0.000 description 6
- 238000000926 separation method Methods 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 208000032456 Hemorrhagic Shock Diseases 0.000 description 1
- 206010049771 Shock haemorrhagic Diseases 0.000 description 1
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011143 downstream manufacturing Methods 0.000 description 1
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Abstract
The utility model provides the strainer of tumour cell in a kind of separating blood fluid, plural sheet shape Filter column is provided with in described strainer, every sub-Filter column all uses fixed support and trace-etching-film jointly to form independently three-dimensional filtration channel, two large surfaces vertical with its thickness direction thread in described sub-Filter column all use track etching membrane closure, and other three little surfaces except sub-post fluid intake use track etching membrane closure or use fixed support material to close; The aperture of described trace-etching-film is 5-25um; Distance between the size of described sub-Filter column and sub-Filter column meets certain size range.The strainer of the utility model gained can be applied to the on-line filtration to tumour cell in living animal (comprising human body) blood circulation in therapeutic treatment.
Description
Technical field
The utility model relates to medical equipment technical field, is specifically related to the strainer of tumour cell in a kind of separating blood fluid and corresponding single unit system.
Background technology
The tumour cell that the strainer containing trace-etching-film can be used to come in ON-LINE SEPARATION blood flow is proposed in prior art.A kind of Fluid film filter cell separation device (as shown in the utility model accompanying drawing 5) is provided in the granted patent CN201410016566.3 as contriver's earlier application of the present utility model, comprise the first driving pump (1), the second driving pump (2), separator column (3), test column (4) and several T-valve and secondary driving pump, described secondary driving pump comprises the first auxiliary pump (11) and the second auxiliary pump (12); One end of described separator column is connected with the first driving pump (1) by the first T-valve (5), the other end is connected with the second driving pump (2) by the second T-valve (6), and described test column (4) is connected with the 3rd porthole of the first T-valve (5); At least five root Filter columns in parallel are comprised in described separator column (3), described sub-Filter column comprises fixed support and is attached to the polycarbonate of fixed support bottom and side surrounding or the trace-etching-film (7) of polyester material, and track etching membrane pore size is 5-25 μm; Described test column (4) comprises two portions up and down of flexible connection, two-part outside all arranges the fluid passage mouth (8) adapted with pipeline, interior vacancy between two portions of sealing arranges the trace-etching-film (7) of one deck polycarbonate or polyester material, and the aperture of trace-etching-film is 5-25 μm; And the 3rd T-valve (9) is set between the first driving pump (1) and the first T-valve (5), another passage of described 3rd T-valve is connected with driving first auxiliary pump (11) of anti-freezing physiological saline, and the 4th T-valve (10) is set between the second T-valve (6) and outlet (21), described 4th T-valve is connected with driving second auxiliary pump (12) of anti-freezing antagonist; Described device utilizes T-valve, separator column and test column to form two operation paths; Wherein, Article 1, path is that the cell suspension of large sample amount enters separator column (3) from cellular liquid container (18) then flow out from the other end through injection port (20), the first driving pump (1), the first T-valve (5), cellular liquid container (18) is got back to by outlet (21) again after filtering, be separated by the continuous circulation of cellular liquid container-pump-separator column, reach the object of the specific large volume cell of high efficiency separation; Article 2 path is adjustment first T-valve (5) and the second T-valve (6), close the connecting passage of injection port (20) and separator column (3), fluid flows counterflow through separator column (3) from the second driving pump (2) and then flows out from the other end, enter test column (4), this path carries out enrichment further to the specific large volume cell that separator column (3) is retained down, concentrated on the filtering membrane of test column (4), to carry out every downstream process detection to cell on film, waste liquid flows out from the other end of test column (4).
Particularly, all disclose columniform separator column (i.e. strainer) in this device in the embodiment of this patent and in accompanying drawing 1 ~ 5 and Fig. 8, sub-Filter column wherein is equally also cylindric.But contriver of the present utility model finds that in research subsequently this separator column is for still having deficiency in this single unit system, those skilled in the art still need to make efforts in this separator column of improvement.
Utility model content
In the further R&D process of the present inventor to described device, contriver finds, it is excessive that useful space utilization ratio as the separator column provided in the embodiment of patent CN201410016566.3 is not high, Filter column fills liquid volume, and difficulty of processing is large, cannot large-scale commercial production.Need to address the problem to improve these shortcomings: one be to solve trace-etching-film firmly, stable, be fixed on problem on described fixed support hermetically, another is the problem increasing " effective filtration area of strainer and filter volume ratio " when technique allows.On the one hand, in order to ensure filtration efficiency, need to increase effective filtration area as far as possible.Filtration area increase can cause again filter liquid filling volume to increase on the other hand.If filter liquid filling volume is excessive, unfavorable to the filtration of living animal, easily there is the situation of the harm living animal life such as hemorrhagic shock.Therefore, desirable strainer should be ensureing that under certain filtration area, its volume is the smaller the better.And in theory, the ratio of " effective filtration area and the filter volume ratio of strainer " of the cylindrical sub-Filter column (such as tiny as hairline Filter column) that diameter is very little can reach the highest, but the technique for fixing of existing trace-etching-film cannot reach this object at all.Namely be diameter greatly to the sub-Filter column of about 3mm, fixing being also very difficult to of the processing of the trace-etching-film on it realizes.And as the sub-Filter column that is about 10mm of the diameter in the embodiment of patent CN201410016566.3 be that to realize the processing of its trace-etching-film fixing, but the difficulty of processing of such separator column is high, be difficult to ensure that sealing is fixing, the more important thing is that " effective filtration area and the filter volume ratio of strainer " value is not high enough again.Trace-etching-film is a kind of very special film, and its material is PC or PET; Its thickness only has 10-20 micron.Because the film fusing point of this material is low, when film is on fixing seal to fixed support, the method for forming in disposable tool cannot be used to fix, and the mode of hot weld or ultra-sonic welded can only be used individually to fix.Disclosed in patent CN201410016566.3 the post of cylinder shape be welded and fixed processing difficulties, stopping property be difficult to ensure.Therefore, this area needs the strainer of a kind of brand new for separating of tumour cell in blood flow (at least comprising the shape and size of fluid channel).
Therefore, the utility model provides the strainer of tumour cell in a kind of separating blood fluid, plural sheet shape Filter column is provided with in described strainer, every sub-Filter column all uses fixed support and trace-etching-film jointly to form independently three-dimensional filtration channel, two large surfaces vertical with its thickness direction thread in described sub-Filter column all use track etching membrane closure, and other three little surfaces except sub-post fluid intake use track etching membrane closure or use fixed support material to close; The aperture of described trace-etching-film is 5-25um; The intermembranous distance of the large surperficial track etching of two panels be oppositely arranged in same sub-Filter column also namely the thickness of sub-Filter column for being no more than 20mm, the distance that in adjacent two sub-Filter columns, the large surperficial track etching of two panels of vicinity is intermembranous is for being no more than 20mm, the length that described son filters is 1 ~ 1000 times of sub-Filter column thickness, and the width that described son filters is 1 ~ 1000 times of sub-Filter column thickness.
The utility model combines " feasibility of technique " and the effective filtration area of the strainer " with filter volume than maximum " these two angles and considers, contriver of the present utility model designs the strainer of shape and size described above.Wherein, the intermembranous distance of the large surperficial track etching of two panels be oppositely arranged in same sub-Filter column also namely the thickness of sub-Filter column be preferably 1 ~ 15mm, be more preferably 3 ~ 10mm; The distance that the large surperficial track etching of two panels contiguous in adjacent two sub-Filter columns is intermembranous is preferably 1 ~ 10mm, is more preferably 2 ~ 8mm.These two sizes (thickness and distance) are too little, can affect the technique for fixing of trace-etching-film, also may affect blood flow; These two sizes then can affect too greatly " effective filtration area and the filter volume ratio of strainer ".The strainer of gained like this can be applied to the on-line filtration to tumour cell in living animal (comprising human body) blood circulation in therapeutic treatment.
In a kind of concrete embodiment, described trace-etching-film to be embedded in described fixed support (fixed support for inlaying certain trace-etching-film is made up of two assemblies cooperatively interacted, and after putting into trace-etching-film, described two assemblies is combined and is welded) and to fix through ultra-sonic welded or hot weld.In the utility model, described trace-etching-film can be attached to described support bracket fastened outside, also can be attached to described support bracket fastened inner side, but more preferably described trace-etching-film to be embedded in described fixed support and to fix through ultra-sonic welded or hot weld.So, both can avoid the use of any adhesives, also can prevent trace-etching-film from coming off from described fixed support, the stopping property of film and fixed support bearing can be guaranteed simultaneously, guarantee that liquid only flows through from film.
Preferably, the length that described son filters is 2 ~ 200 times of sub-Filter column thickness, is more preferably 5 ~ 80 times; The width that described son filters is 1.5 ~ 150 times of sub-Filter column thickness, is more preferably 3 ~ 50 times.More preferably the described son length of filtering and width are 8 ~ 40 times of sub-Filter column thickness, and this is the easy to use and specious of whole strainer and size that is that design.Concrete, the length that described son filters is such as 20 ~ 200mm, and the width that described son filters is such as 15 ~ 150mm; More preferably, the length that described son filters is 50 ~ 150mm, and the width that described son filters is 20 ~ 100mm.
In a kind of concrete embodiment, the filter permanent seat also containing band through hole in described strainer, the shape of described through hole is mated with described sub-post fluid intake, and described fixed support is also provided with the shirt rim being positioned at sub-post fluid intake periphery place.The sub-Filter column having inlayed trace-etching-film inserts in the through hole of described filter permanent seat, and shirt rim is wherein overlapped on described filter permanent seat, and uses ultrasonic welding or hot weld to be sealed.Be different from accompanying drawing 4 in prior art patent CN201410016566.3 and be connected every root Filter column with in Fig. 5 by threaded connector, sub-Filter column in the utility model is by the one-body molded design of shirt rim with the filter permanent seat of band through hole, make the sealing property of the strainer in the utility model better, and safety performance is higher in use procedure, there is no the risk of thread looseness.Preferably, the filter securing cover plate also containing band through hole in described strainer, the shape of described cover plate through hole is mated with described sub-post fluid intake.Described filter securing cover plate covers on described shirt rim, and stopping property and the weather resistance of the Filter column that the utility model is provided further are protected.
In a kind of concrete embodiment, described support bracket fastened two large surfaces are also provided with crossbeam and/or vertical beam, and the trace-etching-film on a large surface is separated into more than 2 pieces (being such as 2 ~ 10 pieces) trace-etching-films by described crossbeam and/or vertical beam.In this preferred version of the present utility model, if be separated into too many block, technique becomes too complicated; And it is stronger to use crossbeam and/or vertical beam a large surperficial trace-etching-film to be separated into 2 ~ 10 pieces of firmness that can make to weld, the more secure rigid of the combination between film and fixed support; And the intensity of trace-etching-film itself relatively uprise thus can the more powerful and lasting impact of fluid resistant.
In a kind of concrete embodiment, on the cross section of sub-Filter column thickness direction, described support bracket fastened cross-sectional shape is that rectangle, isosceles trapezoid or arc waist are trapezoidal, the cross-sectional shape entirety on two of described sub-Filter column large surfaces are rectangular, round rectangle, cydariform, trilateral, isosceles trapezoid or arc waist trapezoidal.
In the utility model, on the cross section of only described sub-Filter column thickness direction shown in the drawings, described support bracket fastened cross-sectional shape is rectangle, but it will be understood by those skilled in the art that this shape is not limited in rectangle; Correspondingly, the size on two large surfaces of described sub-Filter column can be identical, also can not be identical.
In the utility model, only the cross-sectional shape entirety on two of described sub-Filter column shown in the drawings large surfaces is rectangular, but it will be understood by those skilled in the art that this shape is not limited in rectangle; But those skilled in the art know, these shape and size are preferably mated with the shape and size of shell.
In the utility model, the concrete shape of different sub-Filter column can be identical with size, also can not be identical.But the rectangular in cross-section of preferred sub-Filter column thickness direction, and the cross-sectional shape entirety on two of described sub-Filter column large surfaces is rectangular, described strainer also comprises the shell of cubic, and every sub-Filter column is measure-alike, can make so every sheet trace-etching-film and each support bracket fastened shape and size completely the same, be convenient to processing and volume production.
Those skilled in the art know ground, and described shell is just preferably cubic, and cylindrical or Else Rule or the irregular shape of shell all belongs to protection category of the present utility model.
Preferably, the material of described strainer is ABS resin.
In a kind of concrete embodiment, the bottom surface of the enclosure of described strainer is also provided with the projection 36 for being located by sub-Filter column.
The utility model also provides the single unit system of tumour cell in a kind of separating blood fluid, comprise and being connected successively and the flow injecting mouth of energy circulation, the first driving pump, strainer and fluid outlet by major cycle pipeline, described first driving pump is peristaltic pump, and major cycle pipeline between described injection port and strainer is also provided with anti-freezing physiological saline inlet, and major cycle pipeline between described strainer and outlet is also provided with anti-freezing antagonist inlet; And described strainer is strainer as above.
Accompanying drawing explanation
Fig. 1 is the structure drawing of device of tumour cell and the schematic appearance of the utility model middle filtrator in the separating blood fluid in the utility model;
Fig. 2 is that the strainer in the utility model is unassembled to the schematic diagram in shell;
Fig. 3 is the schematic diagram that the utility model middle filtrator is partly assembled in shell;
Fig. 4 is the utility model middle filtrator inner blood flow direction schematic diagram.
In figure, the 1, first driving pump, 3, strainer, 7, trace-etching-film, 9, anti-freezing physiological saline inlet, 10, anti-freezing antagonist inlet, 18, cellular liquid container, 20, injection port, 21, outlet, 31, sub-Filter column, 311, fixed support, 3111, shirt rim, 3112, crossbeam and/or vertical beam, 312, sub-post fluid intake, 32, filter permanent seat, 33, filter securing cover plate, 34, filter inlet, 35, filter outlet, 36, protruding.
Embodiment
The filtration device structure figure in a kind of the utility model is provided in Fig. 2 ~ Fig. 3.The strainer of tumour cell in a kind of separating blood fluid is provided in figure, five sheet shape Filter columns are provided with in described strainer, every sub-Filter column all uses fixed support and trace-etching-film jointly to form independently three-dimensional filtration channel, two large surfaces vertical with its thickness direction thread in described sub-Filter column all use track etching membrane closure, and other three little surfaces except sub-post fluid intake use fixed support material to close; The aperture of described trace-etching-film is 8um; The intermembranous distance of the large surperficial track etching of two panels be oppositely arranged in same sub-Filter column also namely the thickness of sub-Filter column be 7.6mm, the distance that the large surperficial track etching of two panels contiguous in adjacent two sub-Filter columns is intermembranous is 3.4mm, the total length that described son filters is 100mm, four trace-etching-films are divided in the longitudinal direction with three crossbeams, the length of every sheet trace-etching-film is 22mm, the width that described son filters is 36mm, and the corner of every fritter trace-etching-film is all the fillet of R3.5.
1, the area of each fritter filtration zone is:
36×22-3.14×3.5
2(mm)＝792mm
2-38.465mm
2＝753.535mm
2；
2, total filtration area of each sub-Filter column is:
753.535mm
2× 4 (individual) × 2 (face)=6028.28mm
2=60.2828cm
2;
3, total filtration area of whole strainer is: 60.2828cm
2/ × 5=301.4cm
2.
Every sub-Filter column internal volume is 25.68 milliliters, and 5 are 128.4 milliliters altogether.Cubic capacity between sub-Filter column is 84.05 milliliters.Therefore, the cubic capacity in strainer is: 128.4+84.05=212.45ml.
Fig. 1 provides the device of tumour cell in a kind of separating blood fluid in the utility model, comprise and being connected successively and the flow injecting mouth of energy circulation, the first driving pump, strainer and fluid outlet by major cycle pipeline, described first driving pump is peristaltic pump, and major cycle pipeline between described injection port and strainer is also provided with anti-freezing physiological saline inlet, and major cycle pipeline between described strainer and outlet is also provided with anti-freezing antagonist inlet; And described strainer is strainer as above.Cellular liquid container 18 in Fig. 1 is such as living animal or human body, from the pipeline of outlet 21 to cellular liquid container 18 and the blood vessel that is from the pipeline of cellular liquid container 18 to injection port 20 in living animal or body.Blood enters strainer from cellular liquid container then flow out from its other end through injection port, the first driving pump, cellular liquid container is got back to again by outlet, carry out filtering separation by the continuous circulation of cellular liquid container-pump-strainer, reach the object of tumour cell in high efficiency separation blood; To major cycle pipeline, inject anti-freezing physiological saline and anti-freezing antagonist from described anti-freezing physiological saline inlet and described anti-freezing antagonist inlet respectively simultaneously.
Fig. 4 schematically illustrates blood and flow through path (in this figure for containing the situation of two root Filter columns) in described strainer, blood first enters strainer from filter inlet 34, then enter in sub-Filter column under the closing of described filter securing cover plate 33 and filter permanent seat 32, the blood comprising the compositions such as red corpuscle, white corpuscle and thrombocyte leaches to two sides from described trace-etching-film, cancer cells is trapped on described trace-etching-film, and the blood removing cancer cells leaves strainer from filter outlet 35.The circulating filtration of cancer cells is realized by the circulation device described in Fig. 1.
Those skilled in the art can understand ground, if be only provided with a slice sheet shape Filter column in the sheet of filter of each band shell, but use the strainer so multiple (as 2 ~ 5) to be connected in parallel in the single unit system of tumour cell in separating blood fluid, such mode is obviously the equivalent substitute mode in the utility model claim 1 scheme.
The foregoing is only preferred embodiment of the present utility model, be not limited to the utility model, for a person skilled in the art, the utility model can have various modifications and variations.All within spirit of the present utility model and principle, any amendment done, equivalent replacement, improvement etc., all should be included within protection domain of the present utility model.
Claims (10)
1. the strainer of tumour cell in a separating blood fluid, plural sheet shape Filter column (31) is provided with in described strainer (3), every sub-Filter column all uses fixed support (311) and trace-etching-film (7) jointly to form independently three-dimensional filtration channel, two large surfaces vertical with its thickness direction thread in described sub-Filter column all use trace-etching-film (7) to close, and other three little surfaces except sub-post fluid intake (312) use trace-etching-film (7) to close or use fixed support material to close; The aperture of described trace-etching-film is 5-25um;
The intermembranous distance of the large surperficial track etching of two panels be oppositely arranged in same sub-Filter column also namely the thickness of sub-Filter column for being no more than 20mm, the distance that in adjacent two sub-Filter columns, the large surperficial track etching of two panels of vicinity is intermembranous is for being no more than 20mm, the length that described son filters is 1 ~ 1000 times of sub-Filter column thickness, and the width that described son filters is 1 ~ 1000 times of sub-Filter column thickness.
2. strainer according to claim 1, is characterized in that, described trace-etching-film to be embedded in described fixed support and to fix through ultra-sonic welded or thermo-welding; The thickness of described sub-Filter column is 1 ~ 15mm, and the distance that the large surperficial track etching of two panels contiguous in adjacent two sub-Filter columns is intermembranous is 1 ~ 10mm.
3. strainer according to claim 1, is characterized in that, the length that described son filters is 2 ~ 200 times of sub-Filter column thickness, and the width that described son filters is 1.5 ~ 150 times of sub-Filter column thickness.
4. strainer according to claim 1, it is characterized in that, filter permanent seat (32) also containing band through hole in described strainer, the shape of described through hole is mated with described sub-post fluid intake (312), and described fixed support is also provided with the shirt rim (3111) being positioned at sub-post fluid intake (312) periphery place.
5. strainer according to claim 4, is characterized in that, the filter securing cover plate (33) also containing band through hole in described strainer, the shape of described cover plate through hole is mated with described sub-post fluid intake (312).
6. strainer according to claim 1, it is characterized in that, described support bracket fastened two large surfaces are also provided with crossbeam and/or vertical beam (3112), and the trace-etching-film on a large surface is separated into more than 2 pieces trace-etching-films by described crossbeam and/or vertical beam.
7. strainer according to claim 1, it is characterized in that, on the cross section of sub-Filter column thickness direction, described support bracket fastened cross-sectional shape is that rectangle, isosceles trapezoid or arc waist are trapezoidal, the cross-sectional shape entirety on two of described sub-Filter column large surfaces are rectangular, round rectangle, cydariform, isosceles trapezoid or arc waist trapezoidal.
8. strainer according to claim 1, is characterized in that, the rectangular in cross-section of described sub-Filter column thickness direction, and the cross-sectional shape entirety on two of described sub-Filter column large surfaces is rectangular, and described strainer also comprises the shell of cubic.
9. strainer according to claim 8, is characterized in that, the bottom surface of the enclosure of described strainer is also provided with the projection (36) for being located by sub-Filter column.
10. the single unit system of tumour cell in a separating blood fluid, comprise and being connected successively and the flow injecting mouth (20) of energy circulation by major cycle pipeline, first driving pump (1), strainer (3) and fluid outlet (21), described first driving pump (1) is peristaltic pump, and major cycle pipeline between described injection port (20) and strainer (3) is also provided with anti-freezing physiological saline inlet (9), and major cycle pipeline between described strainer (3) and outlet (21) is also provided with anti-freezing antagonist inlet (10), and described strainer (3) is for as the strainer in claim 1 ~ 9 as described in any one.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520192754.1U CN204550562U (en) | 2015-04-01 | 2015-04-01 | The strainer of tumour cell and single unit system in a kind of separating blood fluid |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520192754.1U CN204550562U (en) | 2015-04-01 | 2015-04-01 | The strainer of tumour cell and single unit system in a kind of separating blood fluid |
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|---|---|
| CN204550562U true CN204550562U (en) | 2015-08-12 |
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|---|---|---|---|
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104694381A (en) * | 2015-04-01 | 2015-06-10 | 刘韬 | Filter and integration device for separating tumor cells from blood fluid |
| CN112137684A (en) * | 2020-09-23 | 2020-12-29 | 苏州法兰克曼医疗器械有限公司 | Electrohydraulic lithotriptor for endoscopic surgery |
-
2015
- 2015-04-01 CN CN201520192754.1U patent/CN204550562U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104694381A (en) * | 2015-04-01 | 2015-06-10 | 刘韬 | Filter and integration device for separating tumor cells from blood fluid |
| CN104694381B (en) * | 2015-04-01 | 2017-06-16 | 湖南赛科菲特医疗科技有限责任公司 | The filter and single unit system of tumour cell in a kind of separation blood flow |
| CN112137684A (en) * | 2020-09-23 | 2020-12-29 | 苏州法兰克曼医疗器械有限公司 | Electrohydraulic lithotriptor for endoscopic surgery |
| CN112137684B (en) * | 2020-09-23 | 2021-07-09 | 苏州法兰克曼医疗器械有限公司 | Electrohydraulic lithotriptor for endoscopic surgery |
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Effective date of registration: 20160622 Address after: 410007 Hunan province Changsha Yuhua District, South Road No. 232 building 302 room 4 Jin Fu Yuan Patentee after: THE HUNAN CYCLE FILTER MEDICAL TECHNOLOGY Co.,Ltd. Address before: 410002 Hunan province Changsha Tianxin District Xiangfu Road No. 229 building East Building 402 room 4 Patentee before: Liu Tao |
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