CN204480329U - A kind of skin disease quantitatively evaluating device - Google Patents

A kind of skin disease quantitatively evaluating device Download PDF

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Publication number
CN204480329U
CN204480329U CN201420820167.8U CN201420820167U CN204480329U CN 204480329 U CN204480329 U CN 204480329U CN 201420820167 U CN201420820167 U CN 201420820167U CN 204480329 U CN204480329 U CN 204480329U
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China
Prior art keywords
light source
light
multispectral
skin disease
quantitatively evaluating
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Expired - Fee Related
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CN201420820167.8U
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Chinese (zh)
Inventor
胡晓明
冯云
张凤娟
李勤
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Beijing Institute of Technology BIT
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Beijing Institute of Technology BIT
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  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The utility model relates to a kind of skin disease quantitatively evaluating device, especially the quantitative evaluation of spectral absorption realization to disease of skin such as nevus flammeuss is utilized, device regulates multispectral light source to form structure light image patient surface by spatial light modulator, and synchronous demodulation coded image, obtain the three-dimensional structure light image under patient's multispectral light source, while the three-dimensional model obtaining affected area, and according to light in the incident angle of three-dimensional model and light distribution difference, obtain the multispectral absorption difference of patient part and the normal portions revised, the fine graded of sufferer is completed under the process of computing machine.

Description

A kind of skin disease quantitatively evaluating device
Technical field
The present invention relates to a kind of skin disease quantitatively evaluating device, especially utilize the quantitative evaluation of spectral absorption realization to disease of skin such as nevus flammeuss, assist physician completes meticulous therapeutic scheme.
Background technology
The skin diseases such as nevus flammeus have the features such as lovely luster, sharpness of border, paramophia, lesion degree and the color of dissimilar nevus flammeus patient are closely related, and the evaluation of measuring the Color pair result for the treatment of of patient's patient part is objectively extremely important.Method conventional at present comprises ocular estimate, polarization diffuse reflection imaging, erythema index evaluation etc., also can obtain the deep physiological structures information of sufferer tissue by equipment such as optical coherence tomography, acousto-optic imagings.Ocular estimate, based on subjective discrimination, be diffused into the impact that the methods such as picture and erythema index are subject to ambient light, and the equipment such as optical coherence tomography is difficult to the demand meeting the measurement of affected area large area.
Summary of the invention
The object of the invention is to provide a kind of skin disease quantitatively evaluating device, multispectral light source is regulated to form structure light image patient surface by spatial light modulator, and synchronous demodulation coded image, obtain the three-dimensional structure light image under patient's multispectral light source, while the three-dimensional model obtaining affected area, and according to light in the incident angle of three-dimensional model and light distribution difference, obtain the multispectral absorption difference of patient part and the normal portions revised, under the process of computing machine, complete the fine graded of sufferer.
Implementation process of the present invention mainly comprises device calibration, multispectral three-dimensional reconstruction and spectral absorption correct and form.Device calibration comprises calibration multispectral light source and the optical parametric of projection lens thereof, multispectral light source homogeneity is demarcated, observation camera lens optical parametric is demarcated, and the coordinate transformation parameter etc. between each group optical lens; Multispectral three-dimensional reconstruction process projects the structured light of special spectrum light source by spatial light modulator control light source successively timesharing, and pass through structure light image sequence corresponding to imageing sensor synchronous acquisition, the Three-dimension Reconstruction Model under given spectroscopic light source is obtained according to the parameter (lens optical parameter and coordinate transformation parameter) of demarcating in advance; Finally obtain according to the angled relationships of incident ray and patient surface the correction absorption coefficient that normal structure and sufferer are organized in each spectrum, realize the fine graded of sufferer.
According to a kind of skin disease quantitatively evaluating device of the present invention, comprise optical lens and the computing machine of multispectral light source, spatial light modulator, imageing sensor and correspondence thereof, device is after to the calibration of optical parametric, make the light of described Doppler's light source outgoing via after spatial light modulator coding, project in illing tissue and normal structure, imageing sensor is taken the light be reflected back by illing tissue and normal structure and is carried out imaging, can obtain the three-dimensional structure information of affected area and three-dimensional spectrum absorption difference value after the coded image of computer decoding shooting.
Accompanying drawing explanation
For above-mentioned purpose of the present invention, feature and advantage more can be become apparent, special embodiment below, and coordinate accompanying drawing, be described in detail as follows:
Fig. 1 is system construction drawing.
Fig. 2 is that the one of this device recommends implementation algorithm process flow diagram.
In accompanying drawing, each label represents multispectral light source 1 respectively, spatial light modulator 2, imageing sensor 3, optical lens 4 and computing machine 5, sufferer tissue 6, normal structure 7
Embodiment
Below in conjunction with accompanying drawing and example, the present invention is done and further describes in detail.At this, schematic description and description of the present invention is for explaining the present invention, but not as a limitation of the invention.
Device calibration phase, first system completes the demarcation of internal optics parameter.Namely imageing sensor 3, by a series of sign image of shooting, obtains the optical correction parameter of optical lens 4, as parameters such as the rotation and translation relations between focal length, radial distortion, tangential distortion, two arrangement of mirrors heads under control of the computer.Wherein, multispectral light source 1 and can be able to select three look laser light sources to form by light combination mirror, as the three look laser light sources be made up of the laser light source of red (660nm), green (532nm), blue (445nm), the multi wave length illuminating source such as red (619-630nm), green (516-535) that Tricolor LED also can be selected to form, blue (450-468), also can select other three looks or polychromatic spectra light source as required; The effect of light combination mirror exports a branch of for each wavelength light source synthesis through same optical lens; These parts also can select the mode of single wavelength light source and spatial light modulator and optical lens thereof, then obtain each lens parameters through correcting respectively.
In the three-dimensional reconstruction stage, spatial light modulator 2 by the light of multispectral light source 1 being projected a series of coded image to sufferer tissue 6 and normal structure 7, and can obtain the three-dimensional structure information of affected area after the coded image of synchronous decoding shooting.
The calculation process of spectral absorption calibration phase as shown in Figure 2, according to the reflectivity factor of multispectral Three-dimension Reconstruction Model correction affected area, and the absorption coefficient of the sufferer tissue 6 revised under solving given spectrum according to the image that imageing sensor 3 is taken and normal structure 7, the quantitative evaluation of sufferer tissue 6 is obtained according to this multispectral absorption coefficient.
The above is only embodiments of the invention, not does any pro forma restriction to structure of the present invention.Every above embodiment is done according to technical spirit of the present invention any simple modification, equivalent variations and modification, all still belong in the scope of technical scheme of the present invention.

Claims (3)

1. a skin disease quantitatively evaluating device, it is characterized in that, comprise multispectral light source (1), spatial light modulator (2), the optical lens (4) of imageing sensor (3) and correspondence thereof and computing machine (5), this device is after to the calibration of optical parametric, make the light of Doppler's light source (1) outgoing via after spatial light modulator (2) coding, project in illing tissue (6) and normal structure (7), imageing sensor (3) is taken the light be reflected back by illing tissue (6) and normal structure (7) and is carried out imaging, the three-dimensional structure information of affected area and three-dimensional spectrum absorption difference value can be obtained after the coded image of computing machine (5) decoding shooting.
2. skin disease quantitatively evaluating device according to claim 1, it is characterized in that, by structured light, illumination sufferer tissue (6) and the normal structure (7) of spatial light modulator (2) control multispectral light source (1) successively timesharing projection special spectrum light source.
3. skin disease quantitatively evaluating device according to claim 1, described multispectral light source (1) is made up of light combination mirror and three looks laser light source/Tricolor LED; Described light combination mirror is in order to export a branch of for each wavelength light source synthesis through same optical lens.
CN201420820167.8U 2014-12-19 2014-12-19 A kind of skin disease quantitatively evaluating device Expired - Fee Related CN204480329U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420820167.8U CN204480329U (en) 2014-12-19 2014-12-19 A kind of skin disease quantitatively evaluating device

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Application Number Priority Date Filing Date Title
CN201420820167.8U CN204480329U (en) 2014-12-19 2014-12-19 A kind of skin disease quantitatively evaluating device

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CN204480329U true CN204480329U (en) 2015-07-15

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112295109A (en) * 2020-10-20 2021-02-02 北京理工大学 Therapeutic light control method and photodynamic therapy device using same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112295109A (en) * 2020-10-20 2021-02-02 北京理工大学 Therapeutic light control method and photodynamic therapy device using same

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Granted publication date: 20150715

Termination date: 20171219