CN204351840U - A kind of blood oxygen acquisition system - Google Patents

A kind of blood oxygen acquisition system Download PDF

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CN204351840U
CN204351840U CN201420787110.2U CN201420787110U CN204351840U CN 204351840 U CN204351840 U CN 204351840U CN 201420787110 U CN201420787110 U CN 201420787110U CN 204351840 U CN204351840 U CN 204351840U
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control circuit
blood oxygen
circuit
emitting diode
light emitting
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段发阶
蒋佳佳
张历
王仁大
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Tianjin University
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Tianjin University
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Abstract

A kind of blood oxygen acquisition system, include the control circuit with Bluetooth function, for providing the light emitting diode of light source to finger, for the light-to-frequency converter by finger collection human body blood oxygen optical signal, the output drive end of the control circuit described in the power input of described light emitting diode is connected by light source driving circuit, the signal input part of the outfan connection control circuit of described light-to-frequency converter, described control circuit is communicated with external equipment by Bluetooth protocol, and described control circuit also connects power subsystem and display respectively.Described light emitting diode adopts dual wavelength light emitting diode.This utility model utilizes the single-chip microcomputer being integrated with bluetooth protocol repertory as processor, control dual wavelength light emitting diode luminous according to the sequential of design, and use light-to-frequency converter part directly directly to carry out digitized to photoplethysmographic signal as sensor, decrease the noise that complicated analog circuit brings, simplify the structure of system, achieve the miniaturization of acquisition module.

Description

A kind of blood oxygen acquisition system
Technical field
This utility model relates to a kind of blood oxygen acquisition system.Particularly relate to a kind of blood oxygen acquisition system for wireless pulse BOLD contrast.
Background technology
Oxygen in arterial blood has very important meaning to maintaining the life of people, and in tremulous pulse, the content of oxygen is one of the important indicator judging tissue whether anoxia.The support capacity deficiency of tissue can cause metabolism, the function and morphology structure generation ANOMALOUS VARIATIONS of tissue, and this is a kind of pathological process, is medically referred to as anoxia.One of a kind of disease that anoxia usually occurs clinically, life-critical organ such as the anoxia such as brain, heart is one of major reason causing body death, the situation of oxygen metabolism in blood oxygen saturation direct reaction human metabolism.BOLD contrast can detect human body whether anoxia timely, thus avoids the various disease that causes due to anoxia or death, therefore human body blood oxygen saturation wireless measurement and long-range share system is with a wide range of applications and important practical value.
The metering system of blood oxygen saturation has wound to measure and non-invasive measurement two kinds of methods according to whether having wound to divide to human body to be divided into.The measurement method of blood oxygen saturation of wound is had to be divided into again electrochemical methods and optical densitometric method two kinds, the measurement of wound is had first to take a blood sample by damage of facilities tissue, then with instrumentation, electro chemical analysis is carried out to gathered blood, calculate blood oxygen saturation finally by the result analyzed.This mode needs to use blood sampling apparatus to take a blood sample to human body, and be have wound to measure, electro chemical analysis process time is long, process is complicated.Costly and cannot to carry out continuously monitoring to human body blood oxygen saturation be the disadvantage of this oxygen saturation measurement mode.The advantage that this method is measured is that the result measuring blood oxygen saturation is very accurate, can be applied in many occasions needing Measurement accuracy blood oxygen saturation numerical value such as general anesthesia operation, ewborn infant monitoring.Another kind has wound measuring method to be also need to use hemostix to take a blood sample to human body, then utilizes Medical Instruments to measure the optical density of the blood extracted from human body artery, calculates blood oxygen saturation finally by the result measuring optical density.This method is one of method of Measurement accuracy blood oxygen saturation clinically.The theoretical foundation of this method is Lambert-Beer's law, and the characteristic that make use of HbO2 Oxyhemoglobin different to the absorptance of light under the condition of different optical wavelength with deoxyhemoglobin calculates, the principle of this metering system has developed into the basis of non-invasive measurement blood oxygen saturation.Measure owing to there being wound to have and have wound, time-consuming, effort and cannot the shortcoming of continuous measurement, so these shortcomings in order to solve oxygen saturation measurement, people have invented the method for non-invasive measurement blood oxygen saturation, the method based on Lambert-Beer's law, utilize HbO2 Oxyhemoglobin and the deoxyhemoglobin feature in spectral absorption achieve detecting sphygmus and blood oxygen saturation hurtless measure, low cost, accurately, in real time measure.
Along with science and technology in fast development in recent years, flush bonding processor is in the speed of service and functionally obtain large increase, and the performance of portable set is strengthened gradually, and market share is progressively increased [1]particularly recent years smart mobile phone, the embedded OS such as panel computer and iOS and Andriod developing rapidly and universal, portable communication apparatus is no longer simple communication tool, and can using portable communication apparatus as a human health status record terminal, and personal health information is uploaded to cloud server, realize the wireless measurement of human health information, long-rangely to share and visualized management.According to interrelated data display, by the end of China cellphone subscriber in 2010 more than 7.4 hundred million, wherein smart mobile phone account for again very large proportion [2], smart mobile phone will have very large application potential as human health status record terminal.
BOLD contrast is the important Medical Instruments measuring blood oxygen saturation, and traditional Medical Instruments is all independent wired Medical Instruments, needs the medical personnel of specialty to operate BOLD contrast and measures user, and measurement result under final entry.When not having the medical personnel of specialty, user is difficult to the correct reading realizing correct measurement and measurement result.
As shown in Figure 1, traditional BOLD contrast mainly comprises: MCU, control circuit for light source, light source, photoelectricity testing part, pulse wave treatment circuit form.
MCU controls whole system co-ordination, is controlled and regulates light source to send time-multiplexed light pulse, make light meet measuring condition by control circuit for light source; Photoelectric receiving device receives transillumination and carries out signal condition, time-multiplexed light pulse signal is carried out dual-beam separation, continuous print volume pulsation wave is reduced to again through low-pass filtering, then alternating current-direct current separation is carried out, and control signal gain respectively, finally analog digital conversion feeding MCU is carried out to signal and carry out pulse wave identification and calculate blood oxygen saturation.This BOLD contrast analog circuit is complicated, and circuit parameter requires higher, so performance indications also receive considerable restraint.This system is independent Medical Instruments, uses inconvenience, cannot realize the wireless measurement of blood oxygen saturation, the visualized management of measurement result is shared with long-range.Along with people improve constantly the requirement of BOLD contrast, this BOLD contrast can not meet the demand of people to medical health care products.
Particularly along with the development of mobile interchange, the requirement of people to medical health system improves constantly, as required, medical health equipment is easy to carry, easy to use, simple to operate etc., so health care is inevitable to miniaturization, wireless penetration, the future development such as simple to operate.
Summary of the invention
Technical problem to be solved in the utility model is, provides a kind of blood oxygen acquisition system that can be used for wireless pulse BOLD contrast that can realize acquisition module miniaturization.
The technical scheme that this utility model adopts is: a kind of blood oxygen acquisition system, include the control circuit with Bluetooth function, for providing the light emitting diode of light source to finger, for the light-to-frequency converter by finger collection human body blood oxygen optical signal, wherein, the output drive end of the control circuit described in the power input of described light emitting diode is connected by light source driving circuit, the signal input part of the outfan connection control circuit of described light-to-frequency converter, described control circuit is communicated with external equipment by Bluetooth protocol, described control circuit also connects power subsystem and display respectively.
Described light emitting diode adopts dual wavelength light emitting diode.
Described control circuit also connects for controlling bluetooth work in control circuit and for the button that makes control circuit reset and reset circuit.
Described light-to-frequency converter includes the photodiode of receiving optical signals and exports with the signal of described photodiode the current frequency converter be connected, the control circuit signal input part described in the pulse signal that described current frequency converter exports connects.
Described power subsystem includes the battery for providing power supply, is connected with battery by interface, and for the charging circuit charged the battery, described battery is by a power supply controlling circuit of voltage regulation connection control circuit.
Described charging circuit includes charging chip U1, and described charging chip U1 connects battery interface JI and power interface J2 respectively, described charging chip U1 also connection control circuit.
Described power supply controlling circuit of voltage regulation includes voltage stabilizing chip U3, the power input of described voltage stabilizing chip U3 connects the positive pole of battery, the power output end of voltage stabilizing chip U3 is divided into three tunnels, one road forms VDD power output end, second tunnel is by electric capacity C9 ground connection, 3rd tunnel is by the base stage of resistance R5 connecting triode Q2, and the emitter stage of direct connecting triode Q2, the colelctor electrode of audion Q2 forms VCC power end, the base stage of described audion Q2 is also by the colelctor electrode of resistance R4 connecting triode Q1, the grounded emitter of audion Q 1, base stage is by the level output end PCTL in resistance R3 connection control circuit.
Described button and reset circuit include button S1 and reset chip U6, wherein, two-way is divided in one end of described button S1, bluetooth outfan KEY in one tunnel connection control circuit, resistance R10 of separately leading up to connects power vd D, the other end ground connection of described button S1, the reset terminal RST in described reset chip U6 difference connection control circuit and bluetooth outfan KEY, and connect power vd D.
A kind of blood oxygen acquisition system of the present utility model, utilize the single-chip microcomputer being integrated with bluetooth protocol repertory as processor, control dual wavelength light emitting diode luminous according to the sequential of design, and use light-to-frequency converter part directly directly to carry out digitized to photoplethysmographic signal as sensor, decrease the noise that complicated analog circuit brings, simplify the structure of system, achieve the miniaturization of acquisition module.
Accompanying drawing explanation
Fig. 1 is the formation block diagram of the pulse blood oxygen instrument of prior art;
Fig. 2 is the formation block diagram of the wireless pulse BOLD contrast that this utility model adopts;
Fig. 3 is the formation block diagram of blood oxygen acquisition system of the present utility model;
Fig. 4 is the formation block diagram of light-to-frequency converter in this utility model;
Fig. 5 is the circuit theory diagrams of control circuit in this utility model;
Fig. 6 is the circuit theory diagrams of light source driving circuit in this utility model;
Fig. 7 is the formation block diagram of power subsystem in this utility model;
Fig. 8 is the circuit theory diagrams of charging circuit in this utility model;
Fig. 9 is the circuit theory diagrams of power supply controlling circuit of voltage regulation in this utility model;
Figure 10 is the circuit theory diagrams of button and reset circuit in this utility model.
In figure
1: blood oxygen acquisition system 2: Bluetooth protocol
3: user side smart mobile phone 4:HTTP agreement
5: cloud server 6: other user
11: single-chip microcomputer 12: light source driving circuit
13: light emitting diode 14: light-to-frequency converter
15: display 16: power subsystem
17: finger 18: button and reset circuit
101: light source 102: finger
103: photoelectric receiving device 104: signal condition unit
105: dual-beam separative element 106: alternating current-direct current separative element
107: gain control circuit 108: filter circuit
109:A/D converting unit 110:MCU
111: display and control unit 112:D/A converting unit
113: light intensity regulating unit 114: light source driving circuit
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, a kind of blood oxygen acquisition system of the present utility model is described in detail.
As shown in Figure 2; wireless pulse BOLD contrast includes this utility model claimed blood oxygen acquisition system 1; user side smart mobile phone 3 and the cloud server 5 that gathered human body blood oxygen is processed and stored; described blood oxygen acquisition system 1 is communicated with described user side smart mobile phone 3 by Bluetooth protocol 2, and described user side smart mobile phone 3 is communicated with described cloud server 5 by http protocol.Described user side smart mobile phone 3 is also communicated with other user 6 by network mail 7.
The function that blood oxygen acquisition system of the present utility model realizes has: 1) control light source driving circuit, and driven for emitting lights diode is luminous according to the sequential of setting; 2) utilize the reception of light-to-frequency converter part transmitted through the light of finger tip, then utilize the output pulse of processor to light-to-frequency converter part to count, realize the collection to volume pulsation wave; 3) utilize wireless communication technique and data acquisition module to carry out communication, the volume pulsation wave datum collected is transferred to data processing platform (DPP); 4) display and controlling functions.
As shown in Figure 3, a kind of blood oxygen acquisition system of the present utility model, include the control circuit 11 with Bluetooth function, for providing the light emitting diode 13 of light source to finger 17, for being gathered the light-to-frequency converter 14 of human body blood oxygen optical signal by finger 17, wherein, the power input of described light emitting diode 13 connects the output drive end of described control circuit 11 by light source driving circuit 12, the signal input part of the outfan connection control circuit 11 of described light-to-frequency converter 14, described control circuit 11 is undertaken communicating (as communicated with user side smart mobile phone by Bluetooth protocol 2 and external equipment, ), described control circuit 11 also connects power subsystem 16 and display 15 respectively.Described control circuit 11 also connects for controlling bluetooth work in control circuit 11 and for the button that makes control circuit 11 reset and reset circuit 18.
Light source driving circuit needs two universaling I/O ports to control the drive singal that drive circuit produces HONGGUANG and infrared light; Display and button three universaling I/O ports realize a button and two display lamps; Power module needs four each and every one I/O to realize the management of power supply; Altogether needs two Timer/Counter, one for timing, for controlling sample frequency; Another is for counting, for counting the output pulse of light-to-frequency converter part, thus realizes the digitized to photoplethysmographic; Bluetooth 4.0 is needed to realize the transmission of data.
As shown in Figure 5, described control circuit 11 selects model to be the chip of CC2540, and it is integrated with the chip of enhancement mode 8051 kernel and bluetooth 4.0 protocol stack, there are 21 universaling I/O ports, eight 12 A/D, three Timer/Counter, can complete the function that acquisition module has needed.
CC2450 needs use two crystal oscillators, and they are the real-time clock crystal oscillator of 32.768kHz and the work crystal oscillator of 32MHz respectively, 32MHz crystal oscillator be connected on CC2540 the 22nd, 23 feet, the crystal oscillator of 32.768kHz be connected on CC2540 the 32nd, 33 pins; Power supply this utility model of CC2540 selects 3.3V; Reseting pin is connected on the reset circuit of design, and length can produce reset signal by button; P0.0 foot is the pin multiplexing with A/D, and this utility model uses this foot to measure the electricity of battery; P0.1 foot connects key circuit, has judged whether that button is pressed; P0.4 mouth is used for control survey battery electric quantity, and the benefit of design like this only has measurement battery electric quantity to be just power to circuit, arrives the effect of economize on electricity; P0.6, P0.7 foot, for controlling drive circuit, makes light emitting diode luminous according to the sampling time sequence of design under the driving of drive circuit; P1.0 foot is the complexing pin of intervalometer 1, uses P1.0 foot to connect the output of electrooptical device herein, gathers photoplethysmographic signal; P1.1 foot is used for the instruction of bluetooth connection status, and when P1.1 foot sets low, display lamp is lighted; P2.0 foot, for controlling power supply, when P2.0 foot is set to high level time, being powered to sensor and light source driving circuit, when P2.0 sets low, is stopped power supply, reaching the effect of economize on electricity when not measuring; P2.1, P2.2 are debugging interfaces, and for programming program and debugging, wherein P2.1 is data wire, and P2.2 is clock line; 25,26 pins of CC2540 are used by bluetooth protocol repertory, for carrying out communication with other equipment.
Control circuit 11 in this utility model can also select model to be the chip of CC24300 or the chip of CSR7810 chip or BC31A223A-IVN-E4.
Described light emitting diode 13 adopts dual wavelength light emitting diode.Model can be selected in this utility model to be the dual wavelength light emitting diode of ELM-4001, or to select model to be the dual wavelength light emitting diode of MQ-LAU-001.
The dual wavelength light emitting diode being ELM-4001 as model comprises two light emitting diodes, and one can send the HONGGUANG that peak wavelength is 660nm, and one can send the infrared light that peak wavelength is 880nm.When one end pin is high level, when other end pin is low level, red light-emitting diode conducting, infrared light emitting diodes ends, so glow, otherwise sends out infrared light.When two ends pin be simultaneously high level or low level time, two light emitting diodes all end and not luminous.
Light source driving circuit 12 can adopt model to be the chip of SGM3005, or adopts model to be the chip of MBI1802.As shown in Figure 6, the simulation of model to be the chip of SGM3005 be two single-pole double throws is opened the light, when RD_DRV mouth be low level, IR_DRV mouth for high point at ordinary times, COM1 pin and NC1 pin conducting ground connection, COM2 pin and the conducting of NO2 pin meet power supply VCC, now, 1 pin of ELM-4001 is high level, 2 pins are low level, so can send the LEDs ON of HONGGUANG, can send the light emitting diode cut-off of infrared light, now dual wavelength light emitting diode sends the HONGGUANG of 660nm wavelength.In like manner, when RD_DRV mouth be high level, IR_DRV mouth be low spot at ordinary times, dual wavelength Light-Emitting Diode sends infrared light.If RD_DRV, IR_DRV mouth is high level or low level, so two analog switches all connect to power supply or ground, the pin of dual wavelength light emitting diode do not have pressure drop, so dual wavelength light emitting diode is not luminous.
As shown in Figure 4, described light-to-frequency converter 14 includes the photodiode 141 of receiving optical signals and exports with the signal of described photodiode 141 current frequency converter 142 be connected, control circuit 11 signal input part described in the pulse signal that described current frequency converter 142 exports connects.Model can be adopted to be the chip of TSL237 or to adopt model to be the chip of TSL230.
Model is the chip of TSL237 is a kind of special integrated device, have power supply, export three pins, device inside is integrated with photodiode, operational amplification circuit etc., light intensity signal is directly converted to frequency signal and exports by it, and the enumerator that the pulse frequency of output directly can receive single-chip microcomputer counts.Compared with traditional BOLD contrast, use the BOLD contrast of light-to-frequency converter part to eliminate the analog circuits such as filtering, separation, amplification, simplify the design of instrument, be conducive to the miniaturization of instrument.Then it utilized inner current-frequency transducer to convert specific square wave frequency to light intensity signal exported by inner photodiode induction intensity signal.Its optical frequency response range is from 300nm to 1100nm.
As shown in Figure 7, described power subsystem 16 includes the battery 161 for providing power supply, be connected with battery 161 by interface, for the charging circuit 162 charging to battery 161, described battery 161 is by a power supply controlling circuit of voltage regulation 163 connection control circuit 11.
As shown in Figure 8, described charging circuit 162 includes charging chip U1, and described charging chip U1 connects battery interface JI and power interface J2 respectively, described charging chip U1 also connection control circuit 11.The present embodiment have selected model be SGM4050 as charging chip, lithium battery is charged, charging inlet select be miniUSB.J1 interface connects battery, and the 5th foot of miniUSB connects the input pin of SGM4056, and SGM4056 connects anode by the 8th foot and charges to battery.
Lithium battery voltage is unstable, thus can not use lithium battery directly chip power, this utility model employs voltage stabilizing chip SGM2020-3 and carries out voltage stabilizing, powers to the chip on collecting device.As shown in Figure 9, described power supply controlling circuit of voltage regulation 163 includes the voltage stabilizing chip U3 that model is SGM2020-3, the power input of described voltage stabilizing chip U3 connects the positive pole of battery 161, the power output end of voltage stabilizing chip U3 is divided into three tunnels, one road forms VDD power output end, second tunnel is by electric capacity C9 ground connection, 3rd tunnel is by the base stage of resistance R5 connecting triode Q2, and the emitter stage of direct connecting triode Q2, the colelctor electrode of audion Q2 forms VCC power end, the base stage of described audion Q2 is also by the colelctor electrode of resistance R4 connecting triode Q1, the grounded emitter of audion Q 1, base stage is by the level output end PCTL in resistance R3 connection control circuit 11.
In order to saves energy, when blood oxygen acquisition system is idle, some original paper or circuit can not be powered, as light-to-frequency converter part, light source driving circuit etc.So this utility model devises power supply controlling circuit of voltage regulation, whether this circuit according to the need of collection, thus can control power supply to its power supply.In Fig. 9, when PTCL is in high point at ordinary times, audion Q1 conducting, causes R4 left side pin ground connection, R5 just creates pressure drop, causes audion Q2 conducting, and VCC and VDD is connected, now to light source and sensor power.Otherwise if when PCTL is in low level, Q1 ends, and R5 does not have pressure drop, and Q2 also ends, so VCC and VDD is not connected, not to light source and sensor power.
Because during Bluetooth broadcast be very power consumption, so this utility model also includes a button, for controlling the broadcast of bluetooth, the button of the events such as link and reset circuit 18.This circuit is also the reset of the CC2540 in the chip control circuit of FT7521 by model.As shown in Figure 10, described button and reset circuit 18 include button S1 and reset chip U6, wherein, two-way is divided in one end of described button S1, bluetooth outfan KEY in one tunnel connection control circuit 11, resistance R10 of separately leading up to connect power vd D, the other end ground connection of described button S1, reset terminal RST in described reset chip U6 difference connection control circuit 11 and bluetooth outfan KEY, and connect power vd D.By being keyed on P0.1 mouth, by the level detecting P0.1, CC2540 has judged whether that button is pressed, and when by bond distance on time, FT7521 meeting timing a period of time, produces a reset signal, resets to CC2540.

Claims (8)

1. a blood oxygen acquisition system, it is characterized in that, include the control circuit (11) with Bluetooth function, for providing the light emitting diode (13) of light source to finger (17), for being gathered the light-to-frequency converter (14) of human body blood oxygen optical signal by finger (17), wherein, the power input of described light emitting diode (13) passes through the output drive end of the control circuit (11) described in light source driving circuit (12) connection, the signal input part of the outfan connection control circuit (11) of described light-to-frequency converter (14), described control circuit (11) is communicated with external equipment by Bluetooth protocol (2), described control circuit (11) also connects power subsystem (16) and display (15) respectively.
2. a kind of blood oxygen acquisition system according to claim 1, is characterized in that, described light emitting diode (13) adopts dual wavelength light emitting diode.
3. a kind of blood oxygen acquisition system according to claim 1, it is characterized in that, described control circuit (11) also connects for controlling bluetooth work in control circuit (11) and for the button that makes control circuit (11) reset and reset circuit (18).
4. a kind of blood oxygen acquisition system according to claim 1, it is characterized in that, described light-to-frequency converter (14) includes the photodiode (141) of receiving optical signals and exports with the signal of described photodiode (141) current frequency converter (142) be connected, control circuit (11) signal input part described in the pulse signal that described current frequency converter (142) exports connects.
5. a kind of blood oxygen acquisition system according to claim 1, it is characterized in that, described power subsystem (16) includes the battery (161) for providing power supply, be connected with battery (161) by interface, for the charging circuit (162) charging to battery (161), described battery (161) is by a power supply controlling circuit of voltage regulation (163) connection control circuit (11).
6. a kind of blood oxygen acquisition system according to claim 5, it is characterized in that, described charging circuit (162) includes charging chip U1, described charging chip U1 connects battery interface JI and power interface J2 respectively, and described charging chip U1 is connection control circuit (11) also.
7. a kind of blood oxygen acquisition system according to claim 5, it is characterized in that, described power supply controlling circuit of voltage regulation (163) includes voltage stabilizing chip U3, the power input of described voltage stabilizing chip U3 connects the positive pole of battery (161), the power output end of voltage stabilizing chip U3 is divided into three tunnels, one road forms VDD power output end, second tunnel is by electric capacity C9 ground connection, 3rd tunnel is by the base stage of resistance R5 connecting triode Q2, and the emitter stage of direct connecting triode Q2, the colelctor electrode of audion Q2 forms VCC power end, the base stage of described audion Q2 is also by the colelctor electrode of resistance R4 connecting triode Q1, the grounded emitter of audion Q1, base stage is by the level output end PCTL in resistance R3 connection control circuit (11).
8. a kind of blood oxygen acquisition system according to claim 3, it is characterized in that, described button and reset circuit (18) include button S1 and reset chip U6, wherein, two-way is divided in one end of described button S1, bluetooth outfan KEY in one tunnel connection control circuit (11), resistance R10 of separately leading up to connects power vd D, the other end ground connection of described button S1, reset terminal RST in described reset chip U6 difference connection control circuit (11) and bluetooth outfan KEY, and connect power vd D.
CN201420787110.2U 2014-12-12 2014-12-12 A kind of blood oxygen acquisition system Active CN204351840U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510479A (en) * 2014-12-12 2015-04-15 天津大学 Blood oxygen acquisition system
CN107485375A (en) * 2017-09-19 2017-12-19 姚尚龙 One kind is used for neonatal physiologic index monitoring system

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510479A (en) * 2014-12-12 2015-04-15 天津大学 Blood oxygen acquisition system
CN107485375A (en) * 2017-09-19 2017-12-19 姚尚龙 One kind is used for neonatal physiologic index monitoring system

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