CN204342799U - A kind of magnetic separation device - Google Patents
A kind of magnetic separation device Download PDFInfo
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- CN204342799U CN204342799U CN201420849058.9U CN201420849058U CN204342799U CN 204342799 U CN204342799 U CN 204342799U CN 201420849058 U CN201420849058 U CN 201420849058U CN 204342799 U CN204342799 U CN 204342799U
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- centrifuge tube
- locating slot
- separation device
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- magnetic portion
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Abstract
The utility model relates to tripping device, provides a kind of magnetic separation device.Described magnetic separation device, comprising: base, centrifuge tube retaining plate and magnetic portion; Described base is provided with locating slot; Described centrifuge tube retaining plate is fixed on base, and described centrifuge tube retaining plate is provided with the pore for placing centrifuge tube; Described magnetic portion is fixed on base by locating slot, and can relatively shift one's position by centrifuge tube retaining plate; When described centrifuge tube is placed in pore, fit with magnetic portion bottom it.Relative to prior art, the utility model is under guarantee magnetic separation device can be applicable to the prerequisite of the centrifuge tube of different size, substantially reduce the distance with magnetic portion bottom centrifuge tube, improve the magneticstrength bottom centrifuge tube, shorten in experimentation the time waiting for Magneto separate, magneticsubstance congregational rate is better, improves working efficiency.
Description
Technical field
The utility model relates to tripping device, more particularly, relates to a kind of magnetic separation device.
Background technology
Magnetic separation technique is that development in recent years is got up and is widely used in the isolation technique in the fields such as such as molecular biology, cytobiology, immunology, pharmacy, diagnostics, therapeutics.Can be used for separating bio macromole as nucleic acid, protein, even pharmaceutical carrier, cell etc.With the separation method that other are common, such as the precipitator method, chromatography, centrifuging etc. are compared, and magnetic separation technique has simple and fast, required equipment is simple, extraction cost is low and can effectively keep the features such as the biological activity of separated object.
The process of Magneto separate is roughly as follows: can join in centrifuge tube containing in the solution of sample to be separated in conjunction with the magneticsubstance of sample to be separated, abundant mixing, and be placed on magnetic separation device, now, magneticsubstance is adsorbed on the tube wall by the magnet side of magnetic separation device, then siphon away the solution do not adsorbed with pipettor, and then realize being separated of sample to be separated and other samples.
But, existing magnetic separation device is generally made up of main frame and magnetic sheet, wherein main frame has centrifugal pore, magnet is embedded with in magnetic sheet, in order to the centrifuge tube of all size can be applicable to, magnet in magnetic sheet is parallel with the centrifuge tube that main frame is placed, and the bottom of centrifuge tube is generally taper or U-shaped, fully can not contact with the magnet in magnetic sheet, distant, magneticstrength is lower, thus make in experimentation, to wait for that the time of Magneto separate is longer, and the magneticsubstance in centrifuge tube can not well be assembled, bring constant to follow-up operation, inefficiency.
Therefore need a kind of new magnetic separation device, the centrifuge tube of different size can be applicable to, and magnetic field utilization ratio can be improved.
Utility model content
The purpose of this utility model is to provide a kind of new magnetic separation device, is intended to solve the low problem of prior art magnetic separation device magnetic field utilization ratio.
In order to realize utility model object, the utility model provides a kind of magnetic separation device, comprising: base, centrifuge tube retaining plate and magnetic portion; Described base is provided with locating slot; Described centrifuge tube retaining plate is fixed on base, and described centrifuge tube retaining plate is provided with the pore for placing centrifuge tube; Described magnetic portion is fixed on base by locating slot, and can relatively shift one's position by centrifuge tube retaining plate; When described centrifuge tube is placed in pore, fit with magnetic portion bottom it.
Wherein, described magnetic separation device also can comprise magnetic portion screw; Described magnetic portion is provided with threaded hole on the position corresponding with locating slot; Magnetic portion is fixed on base through locating slot by described magnetic portion screw.
Wherein, described locating slot is waist shaped hole.
Further, described locating slot has 3, is all positioned at the back side of base, parallel each other.
Further, described locating slot has 2, lays respectively at two sides of base, because the plane of symmetry of two sides is symmetrical.
Wherein, described locating slot has multiple, and is arranged in pairs in two sides of base; Described magnetic areas in arbitrary to locating slot between and can insert or extract out.
Further, described locating slot is square opening, tri-angle-holed, semicircle, right-angled trapezium hole or isosceles trapezoid hole.
Wherein, described locating slot has 2, lays respectively at two sides of base, because the plane of symmetry of two sides is symmetrical; Each locating slot has branch's groove that a major trough is communicated with major trough with several; Described magnetic portion is fixed on the end of arbitrary branch's groove to symmetry by sliding.
Wherein, described magnetic portion is provided with several round pie magnet; When described centrifuge tube is placed in pore, the tapered slope bottom it or cambered surface and described round pie magnet are fitted.
Wherein, described centrifuge tube retaining plate is fixed on base with detachable form.
As from the foregoing, the utility model is by locating slot fixed magnetic portion, and magnetic portion can be shifted one's position by centrifuge tube retaining plate relatively, when centrifuge tube is placed in pore, tapered slope bottom centrifuge tube or sphere and magnetic portion are fitted, this is under guarantee magnetic separation device can be applicable to the prerequisite of the centrifuge tube of different size, substantially reduce the distance with magnetic portion bottom centrifuge tube, improve the magneticstrength bottom centrifuge tube, shorten in experimentation the time waiting for Magneto separate, magneticsubstance congregational rate is better, improves working efficiency.
Accompanying drawing explanation
Fig. 1 is the position relationship schematic diagram of magnetic portion 3 and centrifuge tube 4 in the utility model first embodiment; Being the point end bottom centrifuge tube in figure a, is round bottom bottom the centrifuge tube in figure b, is flat bottom the centrifuge tube in figure c.
Fig. 2 is the structure schematic diagram of the magnetic separation device in the utility model first specific embodiment, and 1 is base, and 11 is locating slot, and 12 is positioning mark, and 5 is magnetic portion screw.
Fig. 3 is the side structure schematic diagram of the magnetic separation device in the utility model second specific embodiment, and 1 is base, and 11 is locating slot, and 12 is positioning mark, and 5 is magnetic portion screw.
Fig. 4 is the principle schematic of the adaptive different size centrifuge tube of same magnetic portion in the utility model embodiment, and 41,42,43 is the centrifuge tube of different size, and 3 is magnetic portion.
Fig. 5 is the side structure schematic diagram of several magnetic separation devices in the utility model the 3rd embodiment, and 1 is base, and 11 is locating slot, and 2 is centrifuge tube retaining plate.
Fig. 6 is the side structure schematic diagram of a kind of magnetic separation device in the utility model the 4th embodiment, and 1 is base, and 111 is major trough, and 112 is branch's groove, and 2 is centrifuge tube retaining plate, and 5 is magnetic portion screw.
Fig. 7 is the structural representation of the magnetic separation device in the utility model the 3rd specific embodiment.
Fig. 8 is the structural representation of the magnetic separation device in the utility model the 3rd specific embodiment.
Fig. 9 is the structural representation of the centrifuge tube retaining plate of 3 kinds of specifications that the magnetic separation device in the utility model the 3rd specific embodiment is equipped with.
Embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the utility model is further elaborated.
The utility model proposes the first embodiment, a kind of magnetic separation device, comprising: base, centrifuge tube retaining plate and magnetic portion; Described base is provided with locating slot; Described centrifuge tube retaining plate is fixed on base, and described centrifuge tube retaining plate is provided with the pore for placing centrifuge tube; Described magnetic portion is fixed on base by locating slot, and can relatively shift one's position by centrifuge tube retaining plate; When described centrifuge tube is placed in pore, fit with magnetic portion bottom it.
In the present embodiment, magnetic portion is fixed on base by locating slot, and it can be shifted one's position by centrifuge tube retaining plate relatively; Namely, the position of magnetic portion can convert relative to the centrifuge tube specification of pore placement in centrifuge tube retaining plate, make to fit with magnetic portion bottom centrifuge tube, this is under guarantee magnetic separation device can be applicable to the prerequisite of the centrifuge tube of different size, substantially reduce the distance with magnetic portion bottom centrifuge tube, improve the magneticstrength bottom centrifuge tube, shorten in experimentation the time waiting for Magneto separate, magneticsubstance congregational rate is better, improves working efficiency.
Generally, in a magnetic resolution experiment, the centrifuge tube specification used is consistent.Wherein, centrifuge tube can be divided into the point end, round bottom and flat three types by bottom.When centrifuge tube is the point end, magnetic portion is fitted with the tapered slope at the point end, as shown in Figure 1a; When centrifuge tube is round bottom, the sphere of magnetic portion and round bottom is fitted, as shown in Figure 1 b; When centrifuge tube is flat, magnetic portion and flat part or all of laminating, as illustrated in figure 1 c.
Wherein, the position between magnetic portion and centrifuge tube retaining plate is adjustable, can have multiple implementation, will be further elaborated below the utility model by multiple embodiment.
In the second embodiment of the present utility model, described magnetic separation device also comprises magnetic portion screw; Described magnetic portion is provided with threaded hole on the position corresponding with locating slot; Magnetic portion is fixed on base through locating slot by described magnetic portion screw.
That is, in the present embodiment, magnetic portion is fixed on base by dismountable form.Corresponding adaptive magnetic portion can be prepared for the centrifuge tube of different size.Such as: for 0.2 magnetic portion of 0.2mL centrifuge tube, for 0.5 magnetic portion of 0.5mL centrifuge tube, for 1.5 magnetic portion of 1.5mL centrifuge tube.
Preferably, described locating slot is waist shaped hole.
Described locating slot can be one or more.
In the first specific embodiment, as shown in Figure 2, described locating slot has 3, is all positioned at the back side of base, parallel each other.
In the second specific embodiment, as shown in Figure 3, described locating slot has 2, lays respectively at two sides of base, because the plane of symmetry of two sides is symmetrical.
It should be noted that, in first, second specific embodiment, by the compensating roller of the magnetic portion screw through locating slot, magnetic portion is fixed in locating slot, and change the position of magnetic portion according to the centrifuge tube of the different size specifications that centrifuge tube retaining plate is placed, thus magnetic centrifugal device is made to be applicable to the centrifuge tube of different size.
As shown in Figure 4, bottom centrifuge tube, be the point end, round bottom or flat, and when being different in centrifuge tube size, magnetic portion can not being changed, and just realize magnetic resolution by the centrifuge tube retaining plate changing adaptive dimension centrifuge tube; Namely, by the position control of the pore on centrifuge tube retaining plate, the projection in the horizontal plane of the bottom of the centrifuge tube of the different size be fixed in pore all can be overlapped with same magnetic portion, only need the laminating regulating magnetic portion position in vertical direction can realize bottom magnetic portion and centrifuge tube.On this basis, described base back surface also can comprise positioning mark, and as shown in Figure 2,3, each positioning mark is positioned at locating slot side, and the position of magnetic portion screw when being placed on centrifuge tube retaining plate with the centrifuge tube of each specification is respectively corresponding.Be convenient to the specification according to centrifuge tube, the position of quick position magnetic portion, improve conventional efficient.
In the 3rd embodiment of the present utility model, described locating slot has multiple, and is arranged in pairs in two sides of base; Described magnetic areas in arbitrary to locating slot between and can insert or extract out.
It should be noted that, in the present embodiment, shape and the magnetic portion of locating slot adapt, and the position of magnetic portion screw when each pair of locating slot is placed on centrifuge tube retaining plate with the centrifuge tube of different size is respectively corresponding.This programme can the position of quick position magnetic portion, improves conventional efficient.
Preferably, described locating slot is square opening (as shown in Figure 5), tri-angle-holed, right-angled trapezium hole or isosceles trapezoid hole (as shown in Figure 5).
As shown in Figure 5 a, this magnetic separation device only has a centrifuge tube retaining plate 2, is fixed on base 1, location notch hole is square, and magnetic portion is rectangular strip, adapts with each locating slot 11, can insert from locating slot or extract out, and be fixed between arbitrary right locating slot.Magnetic portion according to the specification of fixing centrifuge tube, and can be inserted in different right locating slot 11 by this magnetic separation device, ensures the laminating bottom magnetic portion and centrifuge tube.
As shown in Figure 5 b, this magnetic separation device has two centrifuge tube retaining plates 2, is separately fixed at the both sides, front and back at base 1 top; For each centrifuge tube retaining plate 2, respectively have 3 pairs of locating slots 11, locating slot 11 is square, and magnetic portion is rectangular strip, adapts with each locating slot 11, can insert from locating slot or extract out, and is fixed between arbitrary right locating slot.Magnetic portion insertion can according to the specification of fixing centrifuge tube, and be fixed in the locating slot 11 of tackling mutually by this magnetic separation device, ensures the laminating bottom magnetic portion and centrifuge tube; In addition, this magnetic separation device can carry out magnetic resolution to the sample in the centrifuge tube of two groups of identical or different specifications simultaneously, both the treatable sample size of each magnetic resolution experiment had been increased, magnetic resolution can be carried out to the sample in the centrifuge tube of two kinds of different sizes again simultaneously, operate more convenient, accelerate conventional efficient.
As shown in Figure 5 c, this magnetic separation device has two centrifuge tube retaining plates 2, is separately fixed at the both sides, front and back at base 1 top; Locating slot 11 is isosceles trapezoid, and magnetic portion is strip, adapts with each locating slot 11, can insert from locating slot or extract out, and is fixed between arbitrary right locating slot.This magnetic separation device can carry out magnetic resolution to the sample in the centrifuge tube of two groups of same sizes simultaneously, increases the treatable sample size of each magnetic resolution experiment, improves conventional efficient.
In the 4th embodiment of the present utility model, described locating slot has 2, lays respectively at two sides of base, and because of the plane of symmetry of two sides symmetrical; Each locating slot has branch's groove that a major trough is communicated with major trough with several; Described magnetic portion is fixed on the end of arbitrary branch's groove to symmetry by sliding.
Magnetic portion in the present embodiment when shifting one's position, avoids extraction and the insertion of magnetic portion relative to the 3rd embodiment, but the formal argument position by sliding, efficiency is higher also more convenient.
As shown in Figure 6, this magnetic separation device has a centrifuge tube retaining plate 2, be fixed on base 1 top, two sides of base 1 have a locating slot respectively, and these two locating slots are because of the plane of symmetry symmetry of two sides, this locating slot has a major trough 111 and three branch's grooves 112, and branch's groove 112 is communicated with major trough 111, magnetic portion is fixed on base 1 by magnetic portion screw 5, and can slide into another to branch groove to branch's groove 112 through major trough 111 from arbitrary.The position of each pair of branch's groove can make magnetic portion fit with the bottom of centrifuge tube of the dimension being placed on centrifuge tube retaining plate 2 just.
In the 5th embodiment of the present utility model, described magnetic portion is provided with several round pie magnet; When described centrifuge tube is placed in pore, the tapered slope bottom it or cambered surface and described round pie magnet are fitted.
In the 6th embodiment of the present utility model, described centrifuge tube retaining plate is fixed on base with detachable form.
In the 3rd specific embodiment of the present utility model, as shown in Fig. 7,8,9, a magnetic separation device comprises base 1, centrifuge tube retaining plate 2, magnetic portion 3, magnetic portion screw 5 and centrifuge tube retaining plate screw 6.The back side of base 1 is provided with 3 locating slots 11, and the hole of locating slot 11 is waist shaped hole, is parallel to each other between these 3 locating slots 11.Centrifuge tube retaining plate 2 is provided with the pore 21 that several place centrifuge tube, also respectively there is a through hole 22 at the two ends of centrifuge tube retaining plate 2, be equipped with two threaded holes in the corresponding positions of base 1, centrifuge tube retaining plate 2 is fixed on the threaded hole of base 1 through through hole 22 by centrifuge tube retaining plate screw 6.Magnetic portion 3 is provided with several round pie magnet 31, and is provided with 3 magnetic portion threaded holes in the position corresponding with locating slot 11, and magnetic portion screw 5 screws in magnetic portion threaded hole through locating slot 11, thus magnetic portion 3 is fixed on base 1.By regulating the elasticity between magnetic portion screw 5 and magnetic portion threaded hole, adjustable magnetic portion 3 is relative to the position of centrifuge tube retaining plate 2.When centrifuge tube 4 is placed in pore 21, fit with the round pie magnet 31 in magnetic portion 3 bottom it.
As shown in Figure 9, for the centrifuge tube of 0.2mL, 0.5mL, 1.5mL, this magnetic separation device is equipped with 0.2 centrifuge tube retaining plate 2a respectively, 0.5 centrifuge tube retaining plate 3b, 1.5 centrifuge tube retaining plate 3c.Each centrifuge tube retaining plate be provided with several respectively with the pore 21 of 0.2mL, 0.5mL, 1.5mL centrifuge tube adaptation.
The foregoing is only preferred embodiment of the present utility model; not in order to limit the utility model; all do within spirit of the present utility model and principle any amendment, equivalent to replace and improvement etc., all should be included within protection domain of the present utility model.
Claims (10)
1. a magnetic separation device, is characterized in that, comprising: base, centrifuge tube retaining plate and magnetic portion;
Described base is provided with locating slot;
Described centrifuge tube retaining plate is fixed on base, and described centrifuge tube retaining plate is provided with the pore for placing centrifuge tube;
Described magnetic portion is fixed on base by locating slot, and can relatively shift one's position by centrifuge tube retaining plate;
When described centrifuge tube is placed in pore, fit with magnetic portion bottom it.
2. magnetic separation device according to claim 1, is characterized in that, described magnetic separation device also comprises magnetic portion screw; Described magnetic portion is provided with threaded hole on the position corresponding with locating slot; Magnetic portion is fixed on base through locating slot by described magnetic portion screw.
3. magnetic separation device according to claim 2, is characterized in that, described locating slot is waist shaped hole.
4. magnetic separation device according to claim 3, is characterized in that, described locating slot has 3, is all positioned at the back side of base, parallel each other.
5. magnetic separation device according to claim 3, is characterized in that, described locating slot has 2, lays respectively at two sides of base, because the plane of symmetry of two sides is symmetrical.
6. magnetic separation device according to claim 1, is characterized in that, described locating slot has multiple, and is arranged in pairs in two sides of base; Described magnetic areas in arbitrary to locating slot between and can insert or extract out.
7. magnetic separation device according to claim 6, is characterized in that, described locating slot is square opening, tri-angle-holed, semicircle, right-angled trapezium hole or isosceles trapezoid hole.
8. magnetic separation device according to claim 1, is characterized in that, described locating slot has 2, lays respectively at two sides of base, because the plane of symmetry of two sides is symmetrical; Each locating slot has branch's groove that a major trough is communicated with major trough with several; Described magnetic portion is fixed on the end of arbitrary branch's groove to symmetry by sliding.
9. magnetic separation device according to claim 1, is characterized in that, described magnetic portion is provided with several round pie magnet; When described centrifuge tube is placed in pore, the tapered slope bottom it or cambered surface and described round pie magnet are fitted.
10. magnetic separation device according to claim 1, is characterized in that, described centrifuge tube retaining plate is fixed on base with detachable form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420849058.9U CN204342799U (en) | 2014-12-29 | 2014-12-29 | A kind of magnetic separation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420849058.9U CN204342799U (en) | 2014-12-29 | 2014-12-29 | A kind of magnetic separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204342799U true CN204342799U (en) | 2015-05-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420849058.9U Active CN204342799U (en) | 2014-12-29 | 2014-12-29 | A kind of magnetic separation device |
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| Country | Link |
|---|---|
| CN (1) | CN204342799U (en) |
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2014
- 2014-12-29 CN CN201420849058.9U patent/CN204342799U/en active Active
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