CN204266297U - A kind of pharmaceutical industry purified water stores and induction system - Google Patents
A kind of pharmaceutical industry purified water stores and induction system Download PDFInfo
- Publication number
- CN204266297U CN204266297U CN201420750565.7U CN201420750565U CN204266297U CN 204266297 U CN204266297 U CN 204266297U CN 201420750565 U CN201420750565 U CN 201420750565U CN 204266297 U CN204266297 U CN 204266297U
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- purified water
- water
- water tank
- heat exchanger
- purified
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 232
- 239000008213 purified water Substances 0.000 title claims abstract description 116
- 230000006698 induction Effects 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 claims abstract description 19
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 31
- 238000000746 purification Methods 0.000 claims description 28
- 238000003860 storage Methods 0.000 claims description 19
- 229910052757 nitrogen Inorganic materials 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 4
- 229910001220 stainless steel Inorganic materials 0.000 claims description 4
- 239000010935 stainless steel Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 2
- 238000005070 sampling Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 5
- 238000007726 management method Methods 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 238000007599 discharging Methods 0.000 description 6
- 229910001873 dinitrogen Inorganic materials 0.000 description 3
- 238000011194 good manufacturing practice Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 239000007789 gas Substances 0.000 description 2
- 238000009928 pasteurization Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
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- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The utility model provides a kind of pharmaceutical industry purified water to store and induction system, comprises purifying water tank, pure water delivery pump, heat exchanger and quality detection device; The product water of described purifying water tank to pure water making system stores; The pure water stored in purifying water tank is delivered to each water spot and refluxes to purifying water tank by described pure water delivery pump; The purified water temperature of backflow to purifying water tank automatically adjusts by described heat exchanger; Purified water after described quality detection device heat exchanger regulates automatically carries out quality examination, and the purified water after qualified is flow back into purifying water tank.Pharmaceutical industry purified water that the utility model provides stores and in induction system, heat exchanger can regulate the temperature of purified water automatically, quality detection device can detect the purified water quality of backflow to purifying water tank, and the purified water after qualified is flow back into purifying water tank, do not need again to detect when being thus delivered to each water spot next time, ensure that purified water stores and conveying meets drug quality production management requirement.
Description
Technical Field
The utility model belongs to the bio-pharmaceuticals engineering field, concretely relates to pharmacy industry purified water storage and conveying system.
Background
In the pharmaceutical process, purified water is usually required to prepare liquid medicine, ordinary tap water is made into qualified purified water through a purified water treatment system and is stored in a stainless steel purified water barrel, and then the purified water is conveyed to each water using point through a rear-stage conveying treatment device and then flows back into the purified water barrel.
However, in most of the conventional purified water post-stage transportation treatment apparatuses, the purified water is directly transported to each water consumption point by using the purified water tank and the purified water circulation pump, and is returned to the purified water tank through the circulation pipe. In the process of conveying, whether the water quality at the moment completely meets the requirement or not is judged, and a device for detecting the quality of the purified water put into use is not arranged in the conventional conveying and processing device, so that whether the water quality of the purified water put into use meets the requirement or not cannot be ensured, and the purified water which does not meet the requirement can flow back to the pure water barrel. In order to avoid delivering the purified water which is not qualified to each water consumption point, the purified water which is qualified in detection needs to be reprocessed and then delivered to each water consumption point, so that time and labor are wasted, and the cost is increased.
SUMMERY OF THE UTILITY MODEL
To the purified water that the avoiding of prior art existence is not conform to the requirement of carrying to each water point, just need to handle again and detect qualified purified water and then carry each water point again, so both time-consuming and energy-consuming, the technical problem of increase cost again, the utility model provides a purified water storage of pharmaceutical industry and conveying system makes it accord with the requirement of medicine quality production management.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a purified water storage and delivery system in pharmaceutical industry comprises a purified water tank, a purified water delivery pump, a heat exchanger and a quality detection device; wherein,
the purified water tank stores the produced water of the pure water preparation system;
the pure water conveying pump conveys the pure water stored in the purification water tank to each water using point and reflows to the purification water tank;
the heat exchanger automatically adjusts the temperature of purified water which flows back to the purified water tank;
and the quality detection device is used for detecting the quality of the purified water after the heat exchanger is automatically adjusted, and returning the qualified purified water to the purification water tank.
The utility model provides an among the purified water storage of pharmacy trade and conveying system, the heat exchanger can the automatically regulated purified water's temperature, quality detection device can to the backward flow to the purified water quality of purification water tank detects, and return the purification rivers after qualified back to the purification water tank, therefore carry next time and need not detect again when each water point, reduced the detection cost again when save time, therefore guaranteed that purified water storage and transport accord with the production management requirement of medicine quality.
Further, the purification water tank is double-deck holding water tank, specifically includes double-deck stainless steel water tank, level sensor, temperature sensor, respirator, automatic spray ball, automatic water supply diaphragm valve, drain valve and sample valve.
Further, the purification water tank is provided with a nitrogen seal device for preventing air from entering the top of the purification water tank.
Further, the pure water delivery pump is a sanitary-grade pure water delivery pump.
Furthermore, the heat exchanger is a double-tube plate heat exchanger which can automatically adjust the temperature of purified water during normal operation and can carry out high-temperature disinfection on a purified water conveying pipe network.
Further, purified water inlets and outlets of the double-tube plate heat exchanger are provided with first temperature detectors.
Further, the quality detection device comprises a PH value sensor, a conductivity indicator and a second temperature detector which are sequentially connected in series.
Drawings
Fig. 1 is a schematic view of a flow of a purified water storage and delivery system in the pharmaceutical industry.
In the figure, 1, a purification water tank; 10. a pure water host; 11. a nitrogen inlet device; 12. a nitrogen discharge device; 2. a pure water delivery pump; 20. water consumption; 3. a heat exchanger; 30. a first temperature detector; 31. a steam input line; 32. a condensate outlet line; 33. a steam discharge line; 34. a cold water input line; 35. a hot water output line; 36. a cold water discharge line; 4. a quality detection device; 41. a pH value sensor; 42. a conductivity indicator; 43. a second temperature detector.
Detailed Description
In order to make the technical means, creation features, achievement purposes and functions of the present invention easy to understand and understand, the present invention is further explained by combining with the specific drawings.
Referring to fig. 1, a purified water storage and delivery system for pharmaceutical industry includes a purified water tank 1, a purified water delivery pump 2, a heat exchanger 3 and a quality detection device 4; wherein,
the purification water tank 1 stores the produced water of the pure water preparation system;
the pure water delivery pump 2 delivers the pure water stored in the purification water tank 1 to each water consumption point and returns the pure water to the purification water tank 1;
the heat exchanger 3 automatically adjusts the temperature of purified water which flows back to the purified water tank 1;
and the quality detection device 4 is used for detecting the quality of the purified water after the heat exchanger 3 is automatically adjusted, and returning the qualified purified water to the purified water tank 1.
The utility model provides an among the purified water storage of pharmacy trade and conveying system, the heat exchanger can the automatically regulated purified water's temperature, quality detection device can to the backward flow to the purified water quality of purification water tank detects, and return the purification rivers after qualified back to the purification water tank, therefore carry next time and need not detect again when each water point, reduced the detection cost again when save time, therefore guaranteed that purified water storage and transport accord with the production management requirement of medicine quality.
Specifically, referring to fig. 1, when the purified water storage and delivery system in the pharmaceutical industry provided by the present invention works, the purified water host 10 first delivers the prepared purified produced water to the purified water tank 1 through a pipe network for storage; then the pure water delivery pump 2 delivers the pure water stored in the purified water tank 1 to each water consumption point 20 through a pipe network and flows back to the purified water tank 1, each water consumption point 20 opens or closes a corresponding control valve according to needs, the purified water can be used correspondingly, and the pure water delivery pump 2 can ensure that the flow rate of circulating return water is more than or equal to 1.5 m/s; then, the heat exchanger 3 automatically adjusts the temperature of the purified water which flows back to the purified water tank 1, namely, when the heat exchanger is in normal operation, the heat exchanger 3 can automatically adjust the temperature of the purified water which flows back to the purified water tank 1 to keep the temperature of the purified water at 24-26 ℃; and finally, the quality detection device 4 performs quality detection on the purified water after the heat exchanger 3 is automatically adjusted, the qualified purified water flows back to the purification water tank 1, and the unqualified water is directly discharged.
As a specific example, the purified water tank 1 is a double-layer heat preservation water tank, specifically comprising a double-layer stainless steel water tank (adapted for pasteurization), a liquid level sensor, a temperature sensor, a respirator, an automatic spray ball, an automatic water replenishing diaphragm valve, a drain valve and a sampling valve, and the water tank should be constructed by using a method and technology which are approved by relevant GMP regulations. In this embodiment, adopt double-deck holding water box, can guarantee the purification water temperature better, and reducible calorific loss when the system carries out pasteurization, the energy saving.
As a specific example, referring to fig. 1, the purification water tank 1 is equipped with a nitrogen sealing device for preventing air from entering the top of the purification water tank, and the nitrogen sealing device is mainly used for keeping the pressure of a protective gas (generally nitrogen gas) at the top of the purification water tank constant, so as to prevent the purified water in the purification water tank from directly contacting with air, prevent the purified water from volatilizing and being oxidized, and prevent the purified water from entering the purification water tank 1 and causing the conductivity of the purified water to be increased. Specifically, the nitrogen sealing device comprises a nitrogen inlet device 11 and a nitrogen discharging device 12, when an inlet valve of the purification water tank 1 is opened and purified water is added into the tank, the liquid level rises, the volume of a gas phase part is reduced, the pressure in the purification water tank 1 is increased by the nitrogen gas entering through the nitrogen inlet device 11, when the pressure in the tank is increased to be higher than the pressure set value of the nitrogen discharging device 12, the nitrogen discharging device 12 is opened, the nitrogen gas is released to the outside, the pressure in the tank is reduced, and the nitrogen discharging device 12 is automatically closed when the pressure in the tank is reduced to the pressure set point of the nitrogen discharging device.
As a specific embodiment, the pure water delivery pump 2 is a sanitary pure water delivery pump, the delivery pump of the type has no dead angle, meets the requirements of 2010-version GMP (good manufacturing practice) certification, and is controlled by frequency conversion, so that the pressure of a pipe network can be better stabilized, and the quality of pure water can be ensured.
As a specific embodiment, please refer to fig. 1, the heat exchanger 3 is a double-tube plate heat exchanger capable of automatically adjusting the temperature of purified water during normal operation and performing high-temperature disinfection on a purified water conveying pipe network. Specifically, cold water and steam can be introduced into the double-tube-plate heat exchanger, so that the temperature of the purified water can be automatically adjusted during normal operation, for example, the temperature in summer is higher, the purified water in the conveying pipe network can be cooled by introducing the cold water, the temperature in winter is lower, and the temperature of the purified water in the conveying pipe network can be heated by introducing the steam, so that the temperature of the purified water can be automatically adjusted, and the temperature of the purified water can be kept at 24-26 ℃ during normal operation. As an embodiment, the double tube plate heat exchanger is provided with a steam input line 31, a condensed water output line 32, a steam discharge line 33, a cold water input line 34, a hot water output line 35, a cold water discharge line 36, and control valves for controlling the conduction or the closing of the respective lines; when the cold water needs to be introduced, the control valve of the cold water input pipeline 34 is opened, the cold water enters the double-tube plate heat exchanger to take away the heat, the hot water output pipeline 35 is used for discharging the water with the heat, and if the pressure of the cold water input into the double-tube plate heat exchanger is too large, the control valve of the cold water discharge pipeline 36 is opened to discharge a part of the cold water entering the double-tube plate heat exchanger. Similarly, when steam needs to be introduced, the control valve of the steam input pipeline 31 is opened, the steam enters the double-tube plate heat exchanger to take away the cold energy, the water with the cold energy is discharged through the condensed water output pipeline 32, and if the steam pressure input into the double-tube plate heat exchanger is too large, the control valve of the steam discharge pipeline 33 is opened to discharge a part of the steam entering the double-tube plate heat exchanger.
As a specific example, please refer to fig. 1, the purified water inlet and outlet of the double tube plate heat exchanger are equipped with a first temperature detector 30. Specifically, a first temperature detector 30 is arranged at a purified water inlet and a purified water outlet of the double-tube plate heat exchanger, and the temperature of the inlet and the outlet of the double-tube plate heat exchanger can be monitored so as to ensure that the temperature of purified water is kept at 24-26 ℃ during normal work; meanwhile, steam is introduced into the double-tube plate heat exchanger, and a purified water conveying pipe network can be sterilized at high temperature, so that the temperature of purified water output from the outlet of the double-tube plate heat exchanger is kept at 85 ℃.
As an embodiment, referring to fig. 1, the quality detecting device 4 includes a PH sensor 41, a conductivity indicator 42 and a second temperature detector 43 connected in series. Specifically, the PH sensor 41, the conductivity indicator 42 and the second temperature detector 43, which are connected in series in sequence, detect the PH, the conductivity and the temperature of the purified water output by the heat exchanger 3 at a constant temperature, and when each of the detected values meets a preset requirement, open the control valve of the purified water tank 1 to allow the purified water to flow back into the purified water tank 1, and otherwise, directly discharge the purified water.
The above is only the embodiment of the present invention, not the limitation of the patent scope of the present invention, all the equivalent structures made by the contents of the specification and the drawings are directly or indirectly applied to other related technical fields, all the same principle is within the patent protection scope of the present invention.
Claims (7)
1. A purified water storage and conveying system in pharmaceutical industry is characterized by comprising a purified water tank, a purified water conveying pump, a heat exchanger and a quality detection device; wherein,
the purified water tank stores the produced water of the pure water preparation system;
the pure water conveying pump conveys the pure water stored in the purification water tank to each water using point and reflows to the purification water tank;
the heat exchanger automatically adjusts the temperature of purified water which flows back to the purified water tank;
and the quality detection device is used for detecting the quality of the purified water after the heat exchanger is automatically adjusted, and returning the qualified purified water to the purification water tank.
2. The pharmaceutical industry purified water storage and delivery system according to claim 1, wherein the purified water tank is a double-layer heat preservation water tank, and specifically comprises a double-layer stainless steel water tank, a liquid level sensor, a temperature sensor, a respirator, an automatic spray ball, an automatic water replenishing diaphragm valve, a drain valve and a sampling valve.
3. The pharmaceutical industry purified water storage and delivery system of claim 1, wherein the purified water tank is fitted with a nitrogen seal to prevent air from entering the top of the purified water tank.
4. The pharmaceutical industry purified water storage and delivery system of claim 1, wherein the pure water delivery pump is a sanitary grade pure water delivery pump.
5. The pharmaceutical industry purified water storage and delivery system of claim 1, wherein the heat exchanger is a double tube plate heat exchanger capable of automatically adjusting the temperature of purified water during normal operation and performing high temperature sterilization on a purified water delivery pipe network.
6. The pharmaceutical industry purified water storage and delivery system of claim 5, wherein the purified water inlet and outlet of the double tube sheet heat exchanger are each provided with a first temperature detector.
7. The pharmaceutical industry purified water storage and delivery system of claim 1, wherein the quality detection device comprises a PH sensor, a conductivity indicator, and a second temperature detector in series.
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CN201420750565.7U CN204266297U (en) | 2014-12-03 | 2014-12-03 | A kind of pharmaceutical industry purified water stores and induction system |
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CN201420750565.7U CN204266297U (en) | 2014-12-03 | 2014-12-03 | A kind of pharmaceutical industry purified water stores and induction system |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104846919A (en) * | 2014-12-03 | 2015-08-19 | 重庆摩尔水处理设备有限公司 | Pharmaceutical industry purified water storage and transportation system |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104846919A (en) * | 2014-12-03 | 2015-08-19 | 重庆摩尔水处理设备有限公司 | Pharmaceutical industry purified water storage and transportation system |
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