CN204142736U - A kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit - Google Patents
A kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit Download PDFInfo
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- CN204142736U CN204142736U CN201420574141.XU CN201420574141U CN204142736U CN 204142736 U CN204142736 U CN 204142736U CN 201420574141 U CN201420574141 U CN 201420574141U CN 204142736 U CN204142736 U CN 204142736U
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- interstitialcellstimulating hormone
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Abstract
The utility model relates to a kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit, the utility model utilizes 2 of different sensitivity and more than 2 ovulation tests test paper to be combined in a device, measure women's interstitialcellstimulating hormone (ICSH) (LH) simultaneously, thus determine LH concentration higher than a certain particular value lower than another particular value, the device of this combination and simultaneously detection method, the disposable concentration ranges more accurately determining LH of energy, continuous coverage can judge the time interval of LH peak value more accurately, overcome the limitation of wall scroll single sensitivity ovulation tests test paper, can Quasi-quantitative measurement LH concentration ranges, applicable crowd is more extensive, this detection method is simple to operate, cost is low, applicable family tests oneself and the LH concentration auxiliary detection of hospital.
Description
Technical field
The utility model belongs to biomedicine technical field, relates to a kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit, and particularly relating to one can the test paper combination unit of Quasi-quantitative measurement interstitialcellstimulating hormone (ICSH) (LH) concentration.
Background technology
A kind of glycoprotein hormones that LH is secreted by anterior pituitary basocyte, its protein part is by 204 Amino acid profile α and β, two subunits, and α subunit is identical with HCG with FSH, TSH, only has β subunit to have special structure, both are connected by non-covalent bond, and molecular weight is about 30KD.LH and FSH is pulsatile secretion, therefore has and significantly in a few days and in the daytime make a variation.Ovulation is facilitated on the LH peak in feminine menstrual mid-term.LH is determined at predicting ovulation, diagnosis infertility, research and judge hypothalamus-hypophysis-gonad axis function and about the aspect such as Treatment monitoring of endocrine system disease significant.Also very large value is had to the clinical pharmacology research of the contraceptive for female acting on hypothalamic pituitary gonadal axis, therefore, accurate detection LH concentration value, to the prediction female ovulation time, to the best ovulation period of guidance, or avoid ovulation period and reach contraception, and diagnosis infertility, all to have very important significance about the research of endocrine system disease.
Existing interstitialcellstimulating hormone (ICSH) (LH) detection method mainly contains blood testing and uroscopy.Blood testing, compares and takes time and effort, and needs professional to use, and uroscopy can check by ovulation tests test paper, and method is simple, can family's self-inspection.
Ovulation tests test paper is divided into two kinds, one is semiquantitative, as patent describes with in duty 201110072240.9, when detecting with semiquantitative ovulation tests test paper, the sample of different LH concentration values, the color that detection line (T line) shows is different, by colour developing situation and colorimetric card contrast, corresponding LH concentration value just can be found interval.Produce this semiquantitative test paper higher to technology level requirement, difference between batch will be controlled very closely, otherwise, T line colour developing colour system or color relation and colorimetric inconsistent, because technology is also immature, not also the main product in market at present, only have minority manufacturer production.
Another is observational measurement, this product technology comparative maturity, on market, a lot of producer is all in production, it adopts double-antibody sandwich immune detection principle, association colloid gold immunochromatography technique simultaneously, thus obtain higher sensitivity and specificity, detect the interstitialcellstimulating hormone (ICSH) (LH) in human urine sample for fast qualitative.Test paper adopts anti-human interstitialcellstimulating hormone (ICSH) monoclonal antibody to be coated on detection line (T), and the anti-LH drying of gold mark is placed on gold mark pad, and wherein the anti-LH of detection line is solidification, and it is flowable that the gold of gold mark pad marks anti-LH.During test, sample is upwards flowed by chromatography effect, LH in sample can mark anti-LH specific binding with gold on gold mark pad, and the anti-human interstitialcellstimulating hormone (ICSH) monoclonal antibody on tested survey line is caught, [anti-LH]-[LH] formed-[the anti-LH of gold mark] compound, thus show a red stripes at detection line (T).There are two lines the viewing area of this ovulation tests test strips, article one, be nature controlling line (C line), another is response line (T line), detection line can develop the color to certain density LH antigen through adjustment, and shade is identical with nature controlling line (C line) degree of depth that develops the color, this LH antigen concentration is exactly the sensitivity of this test paper.During test, when sample LH concentration equals sensitivity concentration, detection line equals control line color, be the positive, see concentration now as peak concentration simultaneously, thus judge that women will be ovulated in 24-48 hour, when sample LH concentration is higher than sensitivity concentration, detection line is deeper than control line color, is be the positive, sees concentration now as peak concentration simultaneously, thus judge that women will be ovulated in 14-28 hour, when LH concentration in sample is lower than sensitivity concentration, detection line is shallower than and controls line processed, represents and does not arrive or cross LH peak value.For the peak value of LH, this detection method judges that this is in extensive, also may be that peak value does not arrive, can not accurately judge LH peak value when display is positive, just may produce erroneous judgement to the time of ovulation.
Utility model content
The technical problems to be solved in the utility model overcomes existing defect, provide and a kind ofly simple to operate, result can be easy to the interstitialcellstimulating hormone (ICSH) Test paper combination unit observed, ovulation period accurately can be found by this device, for standby pregnant women, can find best by the time; For not wishing conceived women, can find the time of contraception, stagger ovulation period, and can realize does not need between companion to take contraceptives, and the property enjoyed good fortune is lived; Also by detecting the peak value of LH, a reference factor of sterile reason can be diagnosed; For the women of LH concentration abnormality, by selecting many detection paper of sensitivity concentration between exceptions area, LH hormone abnormality level and Changing Pattern can be detected eaily, avoiding the bitter technique effect of frequent blood drawing.
A kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit, comprise test strips and test paper holder, described test strips is the interstitialcellstimulating hormone (ICSH) test strip of more than two, all described test strips are the test strips that the concentration of mark interstitialcellstimulating hormone (ICSH) is all not identical, and all described test strips are sequentially arranged in described test paper holder by the interstitialcellstimulating hormone (ICSH) concentration of mark is ascending.
On the basis of such scheme, described test paper is 4, and it is the test strips of 25mIU/ml, 50mIU/ml, 75mIU/ml, 100mIU/ml that described test strips is followed successively by mark interstitialcellstimulating hormone (ICSH) concentration.
On the basis of such scheme, described test paper holder is strip plate, described strip plate arranges isolation protruding, and the distance between adjacent two isolation projections is identical with the width of described test strips, and described quantity of isolating projection is that the quantity of described test strips adds 1.
On the basis of such scheme, the length of described strip plate equals the length of described test strips.
On the basis of such scheme, the length of described strip plate is less than the length of described test strips.
On the basis of such scheme, the length of all described isolation projections is equal to the length of described strip plate.
On the basis of such scheme, the length of all described isolation projections is all less than the length of described strip plate.
On the basis of such scheme, described test paper holder comprises upper shell and lower house, described upper shell and described lower house in chimeric mode in four airtight formation inner spaces, limit, described lower house is provided with locating piece, described locating piece is sequentially arranged in the middle part of described lower house, the quantity of described locating piece is that the quantity of described test strips adds 1, distance between adjacent two described locating pieces is identical with the width of described test strips, in space between each adjacent two locating piece, a described test strips is all set, described upper shell is provided with well and view window, the sample pad of the corresponding all described test strips of described well, the detection line of the corresponding all described test strips of described view window and nature controlling line.
The utility model is simple to operate, result is easy to observe, many single sensitivity interstitialcellstimulating hormone (ICSH) Test paper half-quantitative detection women LH concentration levels can being combinationally used simultaneously, by detecting, ovulation can be determined whether, by continuous detecting, the time of ovulating can be judged.
Accompanying drawing explanation
Accompanying drawing is used to provide further understanding of the present utility model, and forms a part for instructions, is used from explanation the utility model, does not form restriction of the present utility model with embodiment one of the present utility model.In the accompanying drawings:
The first structural representation that Fig. 1 is the test paper holder of a kind of interstitialcellstimulating hormone (ICSH) Test paper of the utility model combination unit when being strip plate;
The second structural representation that Fig. 2 is the test paper holder of a kind of interstitialcellstimulating hormone (ICSH) Test paper of the utility model combination unit when being strip plate;
Structural representation when Fig. 3 to be the test paper holder of a kind of interstitialcellstimulating hormone (ICSH) Test paper of the utility model combination unit be upper shell and lower house tabling;
Fig. 4 is the structural representation that the test strips of the utility model interstitialcellstimulating hormone (ICSH) Test paper combination unit is arranged on lower house phase time.
Embodiment
Below in conjunction with accompanying drawing, preferred embodiment of the present utility model is described, should be appreciated that preferred embodiment described herein is only for instruction and explanation of the utility model, and be not used in restriction the utility model.
As Figure 1-4, a kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit, comprise test strips 1 and test paper holder, described test strips 1 is the interstitialcellstimulating hormone (ICSH) test strip of more than two, all described test strips 1 are the test strips that the concentration of mark interstitialcellstimulating hormone (ICSH) is all not identical, and all described test strips 1 are sequentially arranged in described test paper holder by the interstitialcellstimulating hormone (ICSH) concentration of mark is ascending.
On the basis of such scheme, described test strips 1 is 4, and it is the test strips of 25mIU/ml, 50mIU/ml, 75mIU/ml, 100mIU/ml that described test strips 1 is followed successively by mark interstitialcellstimulating hormone (ICSH) concentration.
On the basis of such scheme, described test strips holder is strip plate 20, described strip plate 20 is arranged and isolates protruding 3, the distances between adjacent two isolation protruding 3 are identical with the width of described test strips 1, and described quantity of isolating projection 3 is that the quantity of described test strips adds 1.
On the basis of such scheme, the length of described strip plate 20 equals the length of described test strips 1.
On the basis of such scheme, the length of described strip plate 20 is less than the length of described test strips 1.
On the basis of such scheme, the length of all described isolation protruding 3 is equal to the length (as shown in Figure 1) of described strip plate 20.
On the basis of such scheme, the length of all described isolation protruding 3 is all less than the length (as shown in Figure 2) of described strip plate 20.
On the basis of such scheme, described test paper holder comprises upper shell 21 and lower house 22, described upper shell 21 and described lower house 22 in chimeric mode the four airtight formation inner spaces (as shown in Figure 3) in limit, described lower house 22 is provided with locating piece 23 (as shown in Figure 4), described locating piece 23 is sequentially arranged in the middle part of described lower house 22, the quantity of described locating piece 23 is that the quantity of described test strips adds 1, distance between adjacent two described locating pieces 23 is identical with the width of described test strips, in space between each adjacent two locating piece 23, a described test strips 1 is all set, described upper shell 21 is provided with well 24 and view window 25, the sample pad of the corresponding all described test strips 1 of described well 24, the detection line (T) of the corresponding all described test strips 1 of described view window 25 and nature controlling line (C).
When using the utility model, the container reception sample that user is clean, with sensitivity different ovulation tests test paper combination unit to pattern detection, if all bars are feminine gender, then the LH concentration in expression sample is lower than maximum sensitivity in device.If the test strips had in device is positive, some test strips are negative, then concentration value is on the bar sensitivity concentration being shown as the positive, sensitivity minimization, and are shown as under negative maximum sensitivity concentration.If be all positive, then represent that concentration of specimens is higher than that sensitivity concentration value (concentration value is larger, and sensitivity is lower) of sensitivity minimization, thus sxemiquantitative draws the concentration range in sample.The highest peak value is found from the change of concentration, thus the ovulation period of accuracy of judgement.Namely be the ovulation in 4-8 hour after judging time to peak.
By finding ovulation period comparatively accurately, can, for standby pregnant women, can find best by the time; For not wishing conceived women, can find the time of contraception, stagger ovulation period, and can realize does not need between companion to take contraceptives, and the property enjoyed good fortune is lived; Also by detecting the peak value of LH, a reference factor of sterile reason can be diagnosed; For the women of LH concentration abnormality, by selecting many detection paper of sensitivity concentration between exceptions area, LH hormone abnormality level and Changing Pattern can be detected eaily, avoiding the hardship of frequent blood drawing.
The sensitivity of the test strips of this practicality and quantity can be selected arbitrarily, not by the restriction of accompanying drawing.
Last it is noted that the foregoing is only preferred embodiment of the present utility model, be not limited to the utility model, although be described in detail the utility model with reference to previous embodiment, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.All within spirit of the present utility model and principle, any amendment done, equivalent replacement, improvement etc., all should be included within protection domain of the present utility model.
Claims (8)
1. an interstitialcellstimulating hormone (ICSH) Test paper combination unit, it is characterized in that: comprise test strips (1) and test paper holder, described test strips (1) is the interstitialcellstimulating hormone (ICSH) test strip of more than two, all described test strips (1) are the test strips that the concentration of mark interstitialcellstimulating hormone (ICSH) is all not identical, and all described test strips (1) are sequentially arranged in described test paper holder by the interstitialcellstimulating hormone (ICSH) concentration of mark is ascending.
2. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 1, it is characterized in that: described test strips (1) is 4, it is 25mIU/ml that described test strips (1) is followed successively by mark interstitialcellstimulating hormone (ICSH) concentration, 50mIU/ml, the test strips of 75mIU/ml, 100mIU/ml.
3. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 1 and 2, it is characterized in that: described test strips holder is strip plate (20), described strip plate (20) arranges isolation protruding (3), distance between adjacent two isolation protruding (3) is identical with the width of described test strips (1), and described quantity of isolating protruding (3) is that the quantity of described test strips adds 1.
4. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 3, is characterized in that: the length of described strip plate (20) equals the length of described test strips (1).
5. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 3, is characterized in that: the length of described strip plate (20) is less than the length of described test strips (1).
6. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 4, is characterized in that: the length of all described isolation protruding (3) is equal to the length of described strip plate (20).
7. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 4, is characterized in that: the length of all described isolation protruding (3) is all less than the length of described strip plate (20).
8. interstitialcellstimulating hormone (ICSH) Test paper combination unit according to claim 1 and 2, it is characterized in that: described test paper holder comprises upper shell (21) and lower house (22), described upper shell (21) and described lower house (22) in chimeric mode in four airtight formation inner spaces, limit, described lower house (22) is provided with locating piece (23), described locating piece (23) is sequentially arranged in the middle part of described lower house (22), the quantity of described locating piece (23) is that the quantity of described test strips adds 1, distance between adjacent two described locating pieces (23) is identical with the width of described test strips, in space between each adjacent two locating piece (23), a described test strips (1) is all set, described upper shell (21) is provided with well (24) and view window (25), the sample pad of the corresponding all described test strips (1) of described well (24), the detection line of the corresponding all described test strips (1) of described view window (25) and nature controlling line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420574141.XU CN204142736U (en) | 2014-09-30 | 2014-09-30 | A kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420574141.XU CN204142736U (en) | 2014-09-30 | 2014-09-30 | A kind of interstitialcellstimulating hormone (ICSH) Test paper combination unit |
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| CN204142736U true CN204142736U (en) | 2015-02-04 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105628939A (en) * | 2015-08-21 | 2016-06-01 | 蓝十字生物药业（北京）有限公司 | Grade rapid semi-quantitative ovulation colloidal gold test paper, kit and detection method |
| KR101647469B1 (en) * | 2015-05-29 | 2016-08-10 | 서강대학교산학협력단 | Ovulation test kit |
| CN107389953A (en) * | 2017-07-14 | 2017-11-24 | 天津天合众生医疗科技有限公司 | A kind of method of testing and system |
-
2014
- 2014-09-30 CN CN201420574141.XU patent/CN204142736U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101647469B1 (en) * | 2015-05-29 | 2016-08-10 | 서강대학교산학협력단 | Ovulation test kit |
| CN105628939A (en) * | 2015-08-21 | 2016-06-01 | 蓝十字生物药业（北京）有限公司 | Grade rapid semi-quantitative ovulation colloidal gold test paper, kit and detection method |
| CN107389953A (en) * | 2017-07-14 | 2017-11-24 | 天津天合众生医疗科技有限公司 | A kind of method of testing and system |
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