CN204137485U - For the preparation of the kit of DC-CTL - Google Patents
For the preparation of the kit of DC-CTL Download PDFInfo
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- CN204137485U CN204137485U CN201420558755.9U CN201420558755U CN204137485U CN 204137485 U CN204137485 U CN 204137485U CN 201420558755 U CN201420558755 U CN 201420558755U CN 204137485 U CN204137485 U CN 204137485U
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- box body
- ctl
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- conductive pad
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Abstract
The utility model discloses a kind of kit for the preparation of DC-CTL, comprise kit, lid, be placed in the heat conductive pad in box body, described heat conductive pad is provided with the groove placing Reagent Tube, and described box body upper center position is provided with at least one groove.Described in the utility model employing with the joint of box body for the preparation of the kit lid of DC-CTL is connected without nickel buckle, fixedly secures, content difficult drop-off, safer; Box body groove design can make kit pick and place steadily, and conveniently easily takes; Heat conductive pad has heat conduction, insulation, shockproof properties, and surface has good viscosity, can reach the effect of damping, fixating reagent in the transportation of kit preferably.
Description
Technical field
The utility model belongs to the accommodating box body field that convenience is tested or medical agent transports, deposits, and especially relates to a kind of kit for the preparation of DC-CTL.
Background technology
Immunocyte is adopted and is treated the immune effector cell of the antitumor activity referred to by feeding back cultured and amplified in vitro, the tumor therapeuticing method of direct killing tumour or excitating organism anti tumor immune response.At present, adoptive immunity cell therapy one of major way becoming immunotherapy of tumors.Cytotoxic T lymphocyte (Cytotoxic T Lymphocyte, CTL) and dendritic cell (Dendritic Cell, DC) are 2 important component parts of immune cell therapy.CTL is the antitumor topmost responsiveness lymphocyte of body, and activated by tumour antigen and give antineoplastic specificity, DC is the most powerful professional antigen presenting cells, by offering tumour antigen, effectively resists the Immune escaping mechanism of tumour cell.DC-CTL refers to the T lymphocyte with DC Dual culture, and by the antigen presentation of DC, activated T lymphocytes, induction produces both CTL, DC and CTL associating can produce efficient immune response.
The reagent that current preparation DC-CTL uses mainly comprises Ficoll lymphocyte separation medium, IL-4, GM-CSF, TNF-α, CD3McAb, IFN-γ, IL-1 α, IL-2, various reagent all needs to be configured to working concentration before using, operating process is loaded down with trivial details, extend process prepared by cell, add the pollution probability of operating process.Therefore, develop a kind of kit preparing DC-CTL, optimize cell preparation procedure, for current immunocyte preparation process be very important.
Usually there is following problem in existing kit:
1. pick and place shakiness.Prepare cell reagent used must to refrigerate or freezing, therefore kit must be deposited in refrigerator, and when kit takes out in refrigerator, refrigerator inside and outside temperature difference makes kit surface become moist, and ganoid kit easily comes off from hand.
2. reagent refrigerating effect.Vibration-absorptive material must be used during kit long-distance transport to protect reagent; adopt sponge at present, but sponge heat conductivility is poor, affects thermal conduction effect more; refrigerant outside kit such as dry ice etc. can not carry out heat-conduction effect preferably, and the storage temperature of reagent can not reach optimum regime.
3. reagent identification.Reagent is fixed in kit groove, and mark is blocked, identification difficulty when taking reagent.
Utility model content
The purpose of this utility model is the kit that the transport providing a kind of DC-CTL of being more applicable for prepare reagent is deposited.
For achieving the above object, the technical solution adopted in the utility model is:
For the preparation of a kit of DC-CTL, comprise kit, lid, be placed in the heat conductive pad in box body, described heat conductive pad is provided with the groove placing Reagent Tube, and described box body upper center position is provided with at least one groove.
Further: described box body and lid are integral type, to adopt with the joint of lid at box body and be connected without nickel buckle.
Further: described heat conductive pad surface is provided with slot.
Further: described box body upper center position groove is frosted exasperate groove.
Further: described kit is cuboid, or be the square bodily form, or be cylindrical, or be the cylindroid bodily form.
Further: described in be arranged in box body heat conductive pad below be provided with stay bearing plate.
Described in the utility model employing with the joint of box body for the preparation of the kit lid of DC-CTL is connected without nickel buckle, fixedly secures, content difficult drop-off, safer; Box body groove design can make kit pick and place steadily, and conveniently easily takes; Heat conductive pad has heat conduction, insulation, shockproof properties, surface has good viscosity, can reach the effect of damping, fixating reagent preferably in the transportation of kit, and the refrigerant outside kit can realize preferably heat-conduction effect, the storage temperature of reagent can maintain optimum regime.Label clip can fixed labels, and for the identification of reagent is provided convenience, the replacement operation of label is simple and convenient simultaneously, can carry out the replacing of label as required.
Accompanying drawing explanation
Fig. 1 is kit structural representation described in the utility model;
Fig. 2 is heat conductive pad structural representation described in the utility model.
Detailed description of the invention
Below in conjunction with drawings and Examples, the utility model is described in further detail.
As shown in Figures 1 and 2, the kit of the preparation DC-CTL described in the present embodiment is cuboid, certainly, also as required the kit of preparation DC-CTL described in the utility model can be made the square bodily form, cylindrical, or the cylindroid bodily form.In the utility model, if not otherwise specified, all refer to that lid one side is for upper, under box bottom is.
This kit comprises box body 4, lid 5, is placed in the heat conductive pad 2 in box body, heat conductive pad 2 designs groove, to deposit and to fix various Reagent Tube, is provided with slot on heat conductive pad surface, longitudinally can insert paper clip, be convenient for changing for fixed labels, longitudinal design slot can conserve space simultaneously.Lid 5 adopts with the joint 3 of box body 4 and is connected without nickel buckle, fixedly secures, content difficult drop-off, safer.The upper center design frosted exasperate groove on the left of box body and right side, accordingly, the middle part on the left of lid and right side adopts frosted design, conveniently picks and places, steadily, not easily slippage.
If box body 4 space allows, also stay bearing plate can be set below heat conductive pad 2.
Above content is in conjunction with concrete preferred implementation further detailed description of the utility model, can not assert that concrete enforcement of the present utility model is confined to these explanations.For the utility model person of an ordinary skill in the technical field, without departing from the concept of the premise utility, some simple deduction or replace can also be made, all should be considered as belonging to protection domain of the present utility model.
Claims (6)
1. for the preparation of a kit of DC-CTL, it is characterized in that: comprise kit, lid, be placed in the heat conductive pad in box body, described heat conductive pad is provided with the groove placing Reagent Tube, and described box body upper center position is provided with at least one groove.
2. as claimed in claim 1 for the preparation of the kit of DC-CTL, it is characterized in that: described box body and lid are integral type, to adopt with the joint of lid at box body and be connected without nickel buckle.
3., as claimed in claim 2 for the preparation of the kit of DC-CTL, it is characterized in that: described heat conductive pad surface is provided with slot.
4., as claimed in claim 2 for the preparation of the kit of DC-CTL, it is characterized in that: described box body upper center position groove is frosted exasperate groove.
5. the kit for the preparation of DC-CTL as described in any one of claim 1-4, is characterized in that: described kit is cuboid, or is the square bodily form, or is cylindrical, or is the cylindroid bodily form.
6., as claimed in claim 5 for the preparation of the kit of DC-CTL, it is characterized in that: described in be arranged in box body heat conductive pad below be provided with stay bearing plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420558755.9U CN204137485U (en) | 2014-09-26 | 2014-09-26 | For the preparation of the kit of DC-CTL |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420558755.9U CN204137485U (en) | 2014-09-26 | 2014-09-26 | For the preparation of the kit of DC-CTL |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204137485U true CN204137485U (en) | 2015-02-04 |
Family
ID=52414191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420558755.9U Active CN204137485U (en) | 2014-09-26 | 2014-09-26 | For the preparation of the kit of DC-CTL |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204137485U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109825475A (en) * | 2019-01-31 | 2019-05-31 | 苏州明基医院有限公司 | A kind of the induced activation kit and its application method of DC-CTL cell |
-
2014
- 2014-09-26 CN CN201420558755.9U patent/CN204137485U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109825475A (en) * | 2019-01-31 | 2019-05-31 | 苏州明基医院有限公司 | A kind of the induced activation kit and its application method of DC-CTL cell |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |