CN204134045U - For the stimulating system of musical electric gastrointestinal pacemaker - Google Patents

Abstract

This utility model relates to a kind of stimulating system for musical electric gastrointestinal pacemaker, comprise external electrode, signal extraction module, audio frequency amplifier, single-chip computer control system, Liquid Crystal Module, audio frequency amplifier is used for passing to single-chip computer control system by after the amplification of the music signal of reception, signal extraction module passes to single-chip computer control system after processing for the gastric slow wave signal extracted by external electrode, single-chip computer control system is used for the gastric slow wave signal of acceptance and music signal to carry out superposing rear output digital composite signal through D/A converter, the electrode slice for acting on human body is outputted to after power amplifier.This system is by body surface electrode-feedback electro-gastric signals, music signal is superposed with electro-gastric signals, produce a kind of effectively, do not produce adaptability, with gastrointestinal first-harmonic synchronously change and have-fixed optionally autonomous type digital music electricity pacemaker current acts on human body, is intended to realize individuation, specific effective treatment clinically.

Description

For the stimulating system of musical electric gastrointestinal pacemaker

Technical field

This utility model relates to medical instruments field, particularly a kind of stimulating system for musical electric gastrointestinal pacemaker.

Background technology

Functional gastrointestinal disorder (Functional Gastrointestinal Disorder, FGID) refers to have chronic and symptom of digestive tract that is recurrent, but lack dissect, the clinical syndrome of biochemical and Pathologic changes evidence.The class disease that it is main cause that gastrointestinal motility disorders (Disorders of Gastrointestinal Motility, DGIM) refers to gastrointestinal motility dysfunction.FGID/DGIM is common clinical, frequently-occurring disease, and its prevalence is 10% ~ 30%, and outpatients accounts for 40% ~ 60% of Gastroenterology dept.'s special outpatient clinic.But up to now, FGID/DGIM there is no specific treatment method, its Therapeutic Method mainly relies on short digestive tract power, acid suppression medicine, the medicine regulating visceral sense, anxiety depression and psychological cognition treatment etc., but some drug side effectes are large, what have can not obtain satisfied curative effect, and easily recur after drug withdrawal, curative effect is subject to the impact of other factors.

Different music can produce different reactions to the physiology of people, as biochemical substances (epinephrine, norepinephrine, endorphins, immunoglobulin) and brain wave etc. in the speed of heart rate and pulse, blood pressure, skin potential response, muscle current potential and motor reaction, endocrine and body.The rhythm of music can affect behavior rhythm and the circadian rhythm of people significantly, such as respiration rate, gastrointestinal motility speed rhythm, heart rate.In addition, different music can cause various very different emotional response.Music is also a kind of form of communication of uniqueness simultaneously, and for music, most important interchange meaning is non-language.This interchange feature of music is crucial key factor for clinical treatment, and particularly when the effort fall through of language, music can help to set up good doctor-patient relationship, and this relation treats successful basic motive just.In addition, because music is a kind of exist actually that one to be present in the time and to be formed by physical arrangement (vibrations of air molecule), therefore music can become an effective medium and helps those patients of shrinking back out from reality and society and, from newly coming back to earth the world, set up and the contacting of outside real world.In a word, the utilization one of music many-sidedly can stimulate cerebral cortex, makes patient's decreased sensation to external world; Two be the happiness arousing patient thought contact and emotion, temporarily forget the environment stayed; Three is that music has direct inhibitory action to nervus centralis.In addition, magic of music and fragrance also can attract those social people shunk back to participate in the social activity of music to go, thus change its self-isolation state.

At present, some countries in North America, South America, Europe, Australia and Asia in recent years have all carried out various forms of musical therapy.In recent years, along with the development of electronic technology and Computer Control Technology, novel music electric therapeutic apparatus is constantly released.The prostatitis in the world is walked Ai Fuer international corporation present musical electro-therapy instrument development aspect by France, its company's main product music quality breast care instrument merges the multiple frontier branch of science latest scientific research such as contemporary musical therapy, psychological intervention technology, Chinese and western medical science, electronic engineering, Automated condtrol, in the world, first by Therapeutic Method such as the unique physical therapeutical effect of the psychological application of music and sound field physiological action, musical electric, integrated application is in the health care of female breast, nursing.In China, musical therapy is be created as mark with musical electrotherapy as the subject in modern times, have developed sea God 99-A music electrical therapentic instrument, YP-I music electrical therapentic instrument, sound electricity synchronous physiotherapy machine etc.Music therapy, electrical stimulating therapy and China tradition meridian theory also combine by China medical personnel, create " musical electrotherapy ", and the traditional medicine of motherland has been advanced again a step.Though musical electro-therapy has the history of decades, musical electro-therapy and Musical Electro-acupuncture Therapy be widely used in muscle turn round damage, sciatica, facial paralysis, neurasthenia, initial stage hypertension, cerebral apoplexy sequela, renal calculus rubble etc., but be simple physiotherapy or music modulation.First the research in gastrointestinal pacemaker field originate from abroad, insert electrode brief burst based on percutaneous endoscopic mucosal absorption electrode or peritoneoscope serous coat at first and stimulate acute experiment, there are reverse pace-making and forward pace-making in pace-making direction, and explores its impact on digestive tract power.These experimentatioies demonstrate the existence of gastrointestinal pacemaker system.The clinical application research carried out subsequently also proves that gastrointestinal pacemaker stimulation all has obvious curative effects to diabetic gastroparesis, gastroesophageal reflux disease, functional dyspepsia, gastroptosis and surgical postoperative restoration of gastrointestinal function.The focus of external gastrointestinal pacemaker concentrates on the research of " optimal parameter of pace-making " and " mode of cardiac pacing " at present.But foreign study is based on implanted gastrointestinal pacing protocol, emphasize to directly act on stomach leiomyoma district.Although it has the advantage of accurate positioning, wound is large, and electrode easily comes off, and is not easy to very much clinical and family's use.

The domestic research about gastrointestinal pacemaker is more late, and the Function and its mechanisms of external gastrointestinal pacemaker and electroacupuncture treatment gastrointestinal motility disorders disease is mainly inquired in the research of current domestic association area, has achieved certain progress.Compared with abroad, domestic gastro-intestinal pace maker scheme, mainly based on surface electrical stimulation pace-making and acupoint, avoids operating intervention, greatly reduces application risk, is more likely applicable to long-time use that is clinical and family.But its shortcoming is gastrointestinal pacemaker waveform and frequency is single, pacing parameter is relatively fixing, and selective stimulating effect is more weak, easily produces adaptability, the curative effect of pace-making is single and lasting, can not meet the needs of the meticulous treatment of clinical individualization.Therefore explore safe and effective, have no side effect, selective stimulating effect and do not produce adaptability, new method easy to use is of great significance.

Summary of the invention

The purpose of this utility model is the deficiency existed for prior art, a kind of stimulating system for musical electric gastrointestinal pacemaker is provided, this system is by body surface electrode-feedback electro-gastric signals, music signal is superposed with electro-gastric signals, produce a kind of effectively, do not produce adaptability, with gastrointestinal first-harmonic synchronously change and have-fixed optionally autonomous type digital music electricity pacemaker current acts on human body, is intended to realize individuation, specific effective treatment clinically.

The purpose of this utility model is achieved in that a kind of stimulating system for musical electric gastrointestinal pacemaker, comprise external electrode, signal extraction module, audio frequency amplifier, single-chip computer control system, Liquid Crystal Module, D/A converter, described audio frequency amplifier is used for passing to single-chip computer control system by after the amplification of the music signal of reception, described external electrode is used for extracting gastric slow wave signal transmission to signal extraction module, described signal extraction module passes to single-chip computer control system after processing for the gastric slow wave signal extracted by external electrode, described single-chip computer control system is electrically connected with Liquid Crystal Module, described single-chip computer control system is used for the order of receiving liquid crystal module, the gastric slow wave signal of acceptance and music signal are carried out superpose rear output digital composite signal to D/A converter, single-chip computer control system shows for live signal is exported to Liquid Crystal Module simultaneously, described D/A converter exports to power amplifier after being used for that the digital composite signal of reception is converted to analog mixed-signal, described power amplifier outputs to the electrode slice for acting on human body after being used for that the analog mixed-signal of reception is carried out power amplification.

Described signal extraction module comprises pre-amplifier module, wave filter, follower module, post-amplifier module, the input of described pre-amplifier module is electrically connected with external electrode, the outfan of pre-amplifier module is electrically connected with the input of wave filter, the outfan of wave filter is electrically connected with the input of follower module, the outfan of follower module is electrically connected with the input of post-amplifier module, the outfan of post-amplifier module and an A/D input of single-chip computer control system.

Described pre-amplifier module comprises the integrated single supply instrument amplifier U1 and the first resistance R1 that model is AD623, the 1st of integrated single supply instrument amplifier U1, 8 pins are connected with the two ends of the first resistance R1 respectively, the 2nd of integrated single supply instrument amplifier U1, 3 pins are connected with external electrode respectively, 4th pin of integrated single supply instrument amplifier U1 connects-5V voltage, 7th pin of integrated single supply instrument amplifier U1 connects+5V voltage, the 5th pin ground connection of integrated single supply instrument amplifier U1, 6th pin of integrated single supply instrument amplifier U1 is connected with the input of wave filter.

Described wave filter comprises the amplifier U2 and some resistance that model is LM258, electric capacity, one end of first electric capacity C1 is connected with the outfan of pre-amplifier module, the other end of the first electric capacity C1 respectively with one end of the second resistance R2, one end of 3rd resistance R3 connects, the other end ground connection of the second resistance R2, the other end of the 3rd resistance R3 respectively with one end of the 3rd electric capacity C3, one end of 4th resistance R4 connects, the other end of the 3rd electric capacity C3 and the 1st pin of amplifier U2, the other end of the 4th resistance R4 respectively with one end of the second electric capacity C2, 3rd pin of amplifier U2 connects, the other end ground connection of the second electric capacity C2, 2nd pin of amplifier U2 respectively with one end of the 5th resistance R5, one end of 6th resistance R6 connects, the other end ground connection of the 5th resistance R5, the other end of the 6th resistance R6 and the 1st pin of amplifier U2, 1st pin of amplifier U2 is connected with the 5th pin of amplifier U2, 6th pin of amplifier U2 is respectively at one end of the 7th resistance R7, one end of 8th resistance R8 connects, the other end ground connection of the 7th resistance R7, the other end of the 8th resistance R8 is connected with the 7th pin of amplifier U2, 7th pin of amplifier U2 is connected with the input of follower module, the 8th of amplifier U2, 4 pins respectively with+16V,-16V voltage connects.

Described follower module adopts model to be the amplifier U3 of OPA690.

Described post-amplifier module comprises potentiometer R13, amplifier U4 and some resistance, the in-phase input end of amplifier U4 is connected with one end of the 12 resistance R12, the other end of the 12 resistance R12 is connected with the outfan of follower module, the inverting input of amplifier U4 respectively with the stiff end of potentiometer R13, one end of 14 resistance R14, one end of 15 resistance R15 connects, the movable end of potentiometer R13, another stiff end all connects 16V voltage, the other end ground connection of the 14 resistance R14, the other end of the 15 resistance R15 is connected with the outfan of amplifier U4.

Described single-chip computer control system adopts model to be the embedded chip of STM32F103VBT6.

Have employed such scheme, this utility model is had the following advantages: because native system feeds back electro-gastric signals by external electrode, music signal is superposed with electro-gastric signals, produce a kind of effectively, do not produce adaptability, with gastrointestinal first-harmonic synchronously change and have-fixed optionally autonomous type digital music electricity pacemaker current acts on human stomach pacemaker position, electricity irritation is carried out to stomach, reach the effect for the treatment of, be intended to realize individuation, specific effective treatment clinically.

And use the load signal of real-time electro-gastric signals as music digit signal of the human body fed back by external electrode, the gastrointestinal fundamental frequency that everyone is different can be adapted to, the autonomous type that can carry out pacing parameter adapts to adjustment, selective stimulating effect is strong, not easily produce adaptability, curative effect is lasting, and therapeutic effect is good.And can not only the generation of gastrointestinal pacemaker point be driven to follow-resonance effect by autonomous type by the stimulating current that this method produces, and this stimulating current does not produce adaptability, synchronously change with gastrointestinal first-harmonic, and have-fixed optionally autonomous type digital music electricity pacemaker current, be intended to realize individuation, specific effective treatment clinically.

The stimulating current energy autonomous type produced by native system is driven gastrointestinal pacemaker point to produce and follows-resonance effect, the function of regulation and control digestive tract power and visceral sense and relevant acupuncture point thereof, gastrointestinal nerve, and by vision and audition, act on limbic system to unify backbone network shape structure, and the relation coordinated between reticular formation of brain stem and cerebral cortex functions, good regulating action is played to internal organs and somatic function, nerve, body fluid and endocrine function can be improved, regulation and control emotional state, make each cell of gastrointestinal all in the vibration doing small harmony, excitation energy; And force gastrointestinal pacemaker point to follow rule of wriggling normally, trigger stomach electricity slow wave, recover normal Total Fundoplication and wave amplitude, reach and recover or coordinate gastroenteritic power function activity.

Below in conjunction with drawings and Examples, the utility model is described in further detail.

Accompanying drawing explanation

Fig. 1 is theory diagram of the present utility model;

Fig. 2 is the circuit diagram of pre-amplifier module of the present utility model;

Fig. 3 is the circuit diagram of wave filter of the present utility model;

Fig. 4 is the circuit diagram of follower module of the present utility model;

Fig. 5 is the circuit diagram of post-amplifier module of the present utility model;

Fig. 6 is the circuit diagram of audio frequency amplifier of the present utility model;

Fig. 7 is the circuit diagram of D/A converter of the present utility model;

Fig. 8 is the circuit diagram of power amplifier of the present utility model.

Detailed description of the invention

See Fig. 1, a kind of stimulating system for musical electric gastrointestinal pacemaker, comprise external electrode, signal extraction module, audio frequency amplifier, single-chip computer control system, Liquid Crystal Module, D/A converter, described audio frequency amplifier is used for passing to single-chip computer control system by after the amplification of the music signal of reception, described external electrode is used for extracting gastric slow wave signal transmission to signal extraction module, described signal extraction module passes to single-chip computer control system after processing for the gastric slow wave signal extracted by external electrode, described single-chip computer control system is electrically connected with Liquid Crystal Module, described single-chip computer control system is used for the order of receiving liquid crystal module, the gastric slow wave signal of acceptance and music signal are carried out superpose rear output digital composite signal to D/A converter, single-chip computer control system shows for live signal is exported to Liquid Crystal Module simultaneously, described D/A converter exports to power amplifier after being used for that the digital composite signal of reception is converted to analog mixed-signal, described power amplifier outputs to the electrode slice for acting on human body after being used for that the analog mixed-signal of reception is carried out power amplification.

External electrode selects non polarity A g/AgCl electrode, external electrode plays sensor, the bioelectrical signals of stomach is converted into the signal of telecommunication, external electrode is two electrodes, its electrode 1 and electrode 2, adopt differential mode to extract the bioelectrical signals of stomach, send into bio-signals amplifier, differential mode extracts signal can suppress interference effectively.During treatment, electrode is placed near gastric antrum.

Described signal extraction module comprises pre-amplifier module, wave filter, follower module, post-amplifier module, the input of described pre-amplifier module is electrically connected with external electrode, the outfan of pre-amplifier module is electrically connected with the input of wave filter, the outfan of wave filter is electrically connected with the input of follower module, the outfan of follower module is electrically connected with the input of post-amplifier module, the outfan of post-amplifier module and an A/D input of single-chip computer control system.

Pre-amplifier module employs the AD623 of AD company.AD623 is an integrated single supply instrument amplifier.The alternating CMRR that AD623 increases by providing fabulous increase with gain and error minimally, circuit noise and harmonic wave will because common mode rejection ratio be being suppressed up to still keeping constant during 200Hz.The pre-amplifier module be made up of AD623 as shown in Figure 2.

In the drawings, stomach electricity slow wave signal enters into two inputs of AD623 in a differential manner, can ensure that whole amplifier module has higher common mode rejection ratio like this.The gain of pre-amplifier module can represent with formula below:

$G_1=1+\frac{100\mathrm{k\Ω}}{R_1}$

As shown in the figure, in this circuit, the design gets R ₁=2k Ω, the therefore gain G of this pre-amplifier module ₁=51.

Pre-amplifier module physical circuit connects: described pre-amplifier module comprises the integrated single supply instrument amplifier U1 and the first resistance R1 that model is AD623, the 1st of integrated single supply instrument amplifier U1, 8 pins are connected with the two ends of the first resistance R1 respectively, the 2nd of integrated single supply instrument amplifier U1, 3 pins are connected with external electrode respectively, 4th pin of integrated single supply instrument amplifier U1 connects-5V voltage, 7th pin of integrated single supply instrument amplifier U1 connects+5V voltage, the 5th pin ground connection of integrated single supply instrument amplifier U1, 6th pin of integrated single supply instrument amplifier U1 is connected with the input of wave filter.

Owing to being doped with the noises such as many electrocardios, breathing in electro-gastric signals, therefore the design needs to carry out filtering with wave filter to it.In filter segment, the design uses the band filter of a passive high pass filter and an active low pass filter composition.

Because electro-gastric signals is having higher level component after pre-amplifier module, therefore, in filter module, first allow electro-gastric signals through a passive high pass filter, very effectively can remove the DC component in signal.And in the low pass filter of part below, consider that Butterworth filter has the most smooth amplitude-frequency characteristic in passband, therefore adopt second order Butterworth filter in low pass filter part.Fig. 3 is the filter module in the signal extraction of stomach electricity slow wave.

From Fig. 3, the parameters such as the cut-off frequency of high pass and low pass filter, voltage gain can be calculated.Wherein passive high three-way filter is the firstorder filter be made up of a capacitance and a resistance, its cut-off frequency f _lcan be expressed from the next:

$f_L=\frac{1}{2\mathrm{\π}{R}_2{C}_1}$

And the design have employed amplifier LM258 and feedback capacity C in the low pass filter ₃form.As shown in Fig. 3 .4, LM258 and resistance R ₃, R ₄and electric capacity C ₂, C ₃constitute the Butterworth filter of second order, its cut-off frequency f _hcan represent with following formula:

$f_H=\frac{1}{2\mathrm{\π}\sqrt{R_3{C}_3{R}_4{C}_2}}$

According to the frequency range of stomach electricity slow wave signal, and in order to convenience of calculation, the design will get R ₃=R ₄, C ₂=C ₃, by R in figure ₂, R ₃, R ₄, C ₁, C ₂, C ₃value, obtain f _l=0.003Hz, f _h=0.159Hz, in this pass band, can eliminate other effect of noise such as electrocardio and breathing effectively.The voltage of the output OUT3 of LM258 can represent with following formula:

$\mathrm{OUT}3=(1+\frac{R_8}{R_7})\mathrm{OUT}2=(1+\frac{R_8}{R_7})(1+\frac{R_6}{R_5})\mathrm{OUT}1$

Therefore the gain G of filter module ₂can represent with following formula:

$G_2=\frac{\mathrm{OUT}3}{\mathrm{OUT}1}=(1+\frac{R_8}{R_7})(1+\frac{R_6}{R_5})$

Shown in figure, the design gets R ₅=R ₆=R ₇=R ₈=3k Ω, therefore its gain G ₂=4.

Whole stomach electricity slow wave extracts gain and the pre-amplifier module of circuit, and filter module is relevant with the gain of post-amplifier module, its relation as shown in the formula:

$A_u=G_1\·G_2\·G_3=(1+\frac{100\mathrm{k\Ω}}{R_1})(1+\frac{R_6}{R_5})(1+\frac{R_8}{R_7})(1+\frac{R_{15}}{R_{14}})$

According to the data of modules, A can be obtained _u=4284.

Wave filter physical circuit connects: described wave filter comprises the amplifier U2 and some resistance that model is LM258, electric capacity, one end of first electric capacity C1 is connected with the outfan of pre-amplifier module, the other end of the first electric capacity C1 respectively with one end of the second resistance R2, one end of 3rd resistance R3 connects, the other end ground connection of the second resistance R2, the other end of the 3rd resistance R3 respectively with one end of the 3rd electric capacity C3, one end of 4th resistance R4 connects, the other end of the 3rd electric capacity C3 and the 1st pin of amplifier U2, the other end of the 4th resistance R4 respectively with one end of the second electric capacity C2, 3rd pin of amplifier U2 connects, the other end ground connection of the second electric capacity C2, 2nd pin of amplifier U2 respectively with one end of the 5th resistance R5, one end of 6th resistance R6 connects, the other end ground connection of the 5th resistance R5, the other end of the 6th resistance R6 and the 1st pin of amplifier U2, 1st pin of amplifier U2 is connected with the 5th pin of amplifier U2, 6th pin of amplifier U2 is respectively at one end of the 7th resistance R7, one end of 8th resistance R8 connects, the other end ground connection of the 7th resistance R7, the other end of the 8th resistance R8 is connected with the 7th pin of amplifier U2, 7th pin of amplifier U2 is connected with the input of follower module, the 8th of amplifier U2, 4 pins respectively with+16V,-16V voltage connects.

Signal is had to export because post-amplifier module does not in testing have signal to export in filter module output, therefore the design is in a wave filter and post-amplifier module medium design voltage follower module, can have larger ability to drive other loads of rear class amplification module.Design follower circuit figure as shown in Figure 4:

Described follower module adopts model to be the amplifier U3 of OPA690, and OPA690 has great role to unity gain stable, Voltage Feedback amplifier.Voltage follower plays buffering, isolation, improves load capacity.The input high impedance of collector, exports low-impedance characteristic, makes it can play the effect of impedance matching in circuit, the amplifying circuit of rear stage can be made better to work altogether.

Post-amplifier module is input as low pass filter filtered stomach electricity slow wave signal, the noise signal at this time in signal obviously filtered fall.And the employing of rear class amplifier module is that the OP07 of low elegant high-gain is to form amplifying circuit.The aspects such as the small-signal of sensor.Post-amplifier module is as shown in Figure 5:

In the drawings, R ₁₂build-out resistor, in order to ensure the impedance matching between front stage, R ₁₂must following formula be met:

R ₁₂＝R ₁₄//R ₁₅

Resistance R ₁₃be a potentiometer, can pass through R ₁₃the output voltage of adjustment to amplifying circuit regulate.And the gain of rear class amplifier module is by R ₁₄and R ₁₅common decision, and represent by formula below:

$G_3=1+\frac{R_{15}}{R_{14}}$

As shown in the figure, R ₁₅=2k Ω, R ₁₄=100 Ω, therefore the gain of post-amplifier module is 21.

Post-amplifier module physical circuit connects: described post-amplifier module comprises potentiometer R13, amplifier U4 and some resistance, the in-phase input end of amplifier U4 is connected with one end of the 12 resistance R12, the other end of the 12 resistance R12 is connected with the outfan of follower module, the inverting input of amplifier U4 respectively with the stiff end of potentiometer R13, one end of 14 resistance R14, one end of 15 resistance R15 connects, the movable end of potentiometer R13, another stiff end all connects 16V voltage, the other end ground connection of the 14 resistance R14, the other end of the 15 resistance R15 is connected with the outfan of amplifier U4.

See Fig. 6, MP3 signal processing: acoustic musical signals processing is fairly simple, directly complete homophase by operational amplifier from input interface to amplify, select general integrated operational amplifier LM358 chip, 2 pins are reverse input end, 3 pins are input in the same way, 1 pin is outfan, AP_M3L_GD is for amplifying output signal, music signal is that MP3L_O_GD is connected with resistance R4, the feedback resistance connecting output pin 1 and reverse input pin 2 has selected digital regulation resistance ISL23711 to realize, it is bidirectional power supply, + 5V and-5V voltage are provided simultaneously, pin one and pin one 0 to communicate pin for I2C, be connected with single-chip microcomputer respectively, single-chip microcomputer realizes the control to digital potentiometer resistance by I2C pin.

Single-chip computer control system with ST Microelectronics embedded chip STM32F103VBT6 for core, this circuit is controlled, specifically complete function as follows: realize communicating with liquid crystal display, accept the instruction that user sends, real time data is sent to liquid crystal display simultaneously; Accept gastric slow wave signal and music signal respectively, utilize single-chip microcomputer inside to carry A/D converter and convert analogue signal to digital signal, then realize the superposition of gastric slow wave and music signal according to the instruction that user sends, generate composite signal and export in the mode of numeral.

See Fig. 7, D/A converter realizes digitized composite signal to be converted to analogue signal, and D/A converter selects the MX7224 of MAXIM company, and this is a 8 D/A converter: DB0-DB7 is 8 bit digital inputs, is connected to the composite signal outfan of single-chip microcomputer; Pin two is analog signal output; Employing dual power supply designs, and 18 pins are connected to+5V, and 1 pin is connected to-5V; 3 pins are reference voltage, are connected to 2.5V voltage; 15 pins are connected to single-chip microcomputer as Read-write Catrol port.

See Fig. 8, power amplifier realizes the power amplification for the composite signal exported, the range of signal exported due to D/A converter arrives between+5V at-5V, output is less, act on the sensory current threshold value that human body can not reach human body, need to carry out power ascension, power amplifier is by after composite signal power amplification, by external electrode feedback effect in stomach leiomyoma point region, trigger stomach electricity slow wave, improve stomach electrical quantity, correct abnormal Total Fundoplication, improve digestive tract power and functional activity thereof, thus reach the effect for the treatment of.Power stage: composite signal afterbody need carry out power amplification, adopt power amplifier to realize, select power amplifier chip OPA445, this is a high pressure integrated operational amplifier, adopts dual power supply, 7 pin connection+36V, 4 pin connection-36V; 2 pins are inverting input, and 3 pins are in-phase input end, and 6 pins are amplifier outfan; 3 pins accept the analogue signal that D/A exports, and realize homophase and amplify, and 6 pins export the composite signal after amplifying; This signal is connected on electrode slice, the electricity irritation function to human body can be realized.

This utility model utilizes external electrode to complete extraction for original electro-gastric signals by signal extraction module, the electro-gastric signals of extraction is processed, according to the parameter regulated in advance, music signal and electro-gastric signals are realized superposing, by signal feedback module, stimulus signal is acted on human body again, reach therapeutic effect.This system, by body surface electrode-feedback signal, is carried out self-adaptative adjustment parameter, is made music signal and electro-gastric signals reach optimization and superpose.

Claims (7)

1. the stimulating system for musical electric gastrointestinal pacemaker, it is characterized in that: comprise external electrode, signal extraction module, audio frequency amplifier, single-chip computer control system, Liquid Crystal Module, D/A converter and power amplifier, described audio frequency amplifier is used for passing to single-chip computer control system by after the amplification of the music signal of reception, described external electrode is used for extracting gastric slow wave signal transmission to signal extraction module, described signal extraction module passes to single-chip computer control system after processing for the gastric slow wave signal extracted by external electrode, described single-chip computer control system is electrically connected with Liquid Crystal Module, described single-chip computer control system is used for the order of receiving liquid crystal module, the gastric slow wave signal of acceptance and music signal are carried out superpose rear output digital composite signal to D/A converter, single-chip computer control system shows for live signal is exported to Liquid Crystal Module simultaneously, described D/A converter exports to power amplifier after being used for that the digital composite signal of reception is converted to analog mixed-signal, described power amplifier outputs to the electrode slice for acting on human body after being used for that the analog mixed-signal of reception is carried out power amplification.

2. the stimulating system for musical electric gastrointestinal pacemaker according to claim 1, it is characterized in that: described signal extraction module comprises pre-amplifier module, wave filter, follower module, post-amplifier module, the input of described pre-amplifier module is electrically connected with external electrode, the outfan of pre-amplifier module is electrically connected with the input of wave filter, the outfan of wave filter is electrically connected with the input of follower module, the outfan of follower module is electrically connected with the input of post-amplifier module, the outfan of post-amplifier module and an A/D input of single-chip computer control system.

3. the stimulating system for musical electric gastrointestinal pacemaker according to claim 2, it is characterized in that: described pre-amplifier module comprises the integrated single supply instrument amplifier (U1) and the first resistance (R1) that model is AD623, the 1st of integrated single supply instrument amplifier (U1), 8 pins are connected with the two ends of the first resistance (R1) respectively, the 2nd of integrated single supply instrument amplifier (U1), 3 pins are connected with external electrode respectively, 4th pin of integrated single supply instrument amplifier (U1) connects-5V voltage, 7th pin of integrated single supply instrument amplifier (U1) connects+5V voltage, 5th pin ground connection of integrated single supply instrument amplifier (U1), 6th pin of integrated single supply instrument amplifier (U1) is connected with the input of wave filter.

4. the stimulating system for musical electric gastrointestinal pacemaker according to claim 2, it is characterized in that: described wave filter comprises the amplifier (U2) and some resistance that model is LM258, electric capacity, one end of first electric capacity (C1) is connected with the outfan of pre-amplifier module, the other end of the first electric capacity (C1) respectively with one end of the second resistance (R2), one end of 3rd resistance R3 connects, the other end ground connection of the second resistance (R2), the other end of the 3rd resistance (R3) respectively with one end of the 3rd electric capacity (C3), one end of 4th resistance (R4) connects, the other end of the 3rd electric capacity (C3) and the 1st pin of amplifier (U2), the other end of the 4th resistance (R4) respectively with one end of the second electric capacity (C2), 3rd pin of amplifier (U2) connects, the other end ground connection of the second electric capacity (C2), 2nd pin of amplifier (U2) respectively with one end of the 5th resistance (R5), one end of 6th resistance (R6) connects, the other end ground connection of the 5th resistance (R5), the other end of the 6th resistance (R6) and the 1st pin of amplifier (U2), 1st pin of amplifier (U2) is connected with the 5th pin of amplifier (U2), 6th pin of amplifier (U2) is respectively at one end of the 7th resistance (R7), one end of 8th resistance (R8) connects, the other end ground connection of the 7th resistance (R7), the other end of the 8th resistance (R8) is connected with the 7th pin of amplifier (U2), 7th pin of amplifier (U2) is connected with the input of follower module, the 8th of amplifier (U2), 4 pins respectively with+16V,-16V voltage connects.

5. the stimulating system for musical electric gastrointestinal pacemaker according to claim 2, is characterized in that: described follower module employing model is the amplifier (U3) of OPA690.

6. the stimulating system for musical electric gastrointestinal pacemaker according to claim 2, it is characterized in that: described post-amplifier module comprises potentiometer (R13), amplifier (U4) and some resistance, the in-phase input end of amplifier (U4) is connected with one end of the 12 resistance (R12), the other end of the 12 resistance (R12) is connected with the outfan of follower module, the inverting input of amplifier (U4) respectively with a stiff end of potentiometer (R13), one end of 14 resistance (R14), one end of 15 resistance (R15) connects, the movable end of potentiometer (R13), another stiff end all connects 16V voltage, the other end ground connection of the 14 resistance (R14), the other end of the 15 resistance (R15) is connected with the outfan of amplifier U4.

7. the stimulating system for musical electric gastrointestinal pacemaker according to claim 1, is characterized in that: described single-chip computer control system adopts model to be the embedded chip of STM32F103VBT6.