CN203989291U - A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe - Google Patents
A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe Download PDFInfo
- Publication number
- CN203989291U CN203989291U CN201420319160.8U CN201420319160U CN203989291U CN 203989291 U CN203989291 U CN 203989291U CN 201420319160 U CN201420319160 U CN 201420319160U CN 203989291 U CN203989291 U CN 203989291U
- Authority
- CN
- China
- Prior art keywords
- syringe
- trp
- vibrating device
- tyr
- glu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
This utility model provides a kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe, comprise syringe, be arranged on piston and the piston rod being connected with piston in syringe, also comprise the vibrating device for vibration injection device, described vibrating device comprises for blocking the little pallet of injector syringe, be arranged on the spring of the below of pallet, be fixedly connected on the metab of the relative other end of spring.Described vibrating device is dismountable to be arranged on syringe.The beneficial effects of the utility model: having increased vibrating device on syringe described in the utility model can, before use by medicine mix homogeneously, prevent from flocking together; Described vibrating device is dismountable is simultaneously arranged on syringe, can facilitate reusing of vibrating device, avoids causing the unnecessary wasting of resources.
Description
Technical field
This utility model relates to technical field of medical instruments, relates in particular to a kind of syringe.
Background technology
Goserelin is the analog of a kind of synthetic LHRH, can promote the release of sex gland hormones, effect is strong 50～100 times compared with the LHRH of human secretory, LH-RH analog is the most of receptor in conjunction with hypophysis LH-RH by competition, feedback suppresses the secretion of LH and FSH, thereby suppress the generation of ovarioestrogen, reach the OO therapeutical effect of Drug.
Goserelin is used for the treatment of carcinoma of prostate and menopause is front and the breast carcinoma of climacteric, and the principle of endometriosis is medicine castration.Because the generation of gonadal hormone releasing hormone is subject to the regulation and control of the LHRH that hypothalamus pulsed discharges, p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 and hypophysis LHRH receptors bind, cause receptor down-regulated, thereby inhibition lutein is down to level in menopause by estradiol.This medicine castration in breast cancer treatment field from once occurring having caused concern, all shortcomings of therapeutic modality itself that it can avoid operation, radiotherapy to bring completely, and the function inhibitory action of its ovary is reversible in certain degree.
By suppressing hypophysis release action, in the lutropin of interstitial cell, suppress testosterone and produce, make testosterone concentration in blood drop to castration level.This medicine castration is a primary treatment method of carcinoma of prostate, because there being good toleration to replace in the clinical practice bilateral orchidectomy of more than 50 year and oral estrogen treatment.
In prior art, p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres can be treated patient by the mode of injection conventionally, but p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres easily flocks together in syringe.The purpose of this utility model is to provide a kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe, can, before use by medicine mix homogeneously, prevent from flocking together.Also the stability that has improved medicine, has certain inhibitory action to the degraded of medicine simultaneously.
Utility model content
For p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres in prior art, in syringe, easily flock together, the purpose of this utility model is to provide a kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe.
For achieving the above object, the technical solution adopted in the utility model is as follows:
A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe, comprise syringe, be arranged on piston and the piston rod being connected with piston in syringe, also comprise the vibrating device for vibration injection device, described vibrating device comprises for blocking the little pallet of injector syringe, be arranged on the spring of the below of pallet, be fixedly connected on the metab of the relative other end of spring.
Described vibrating device is dismountable to be arranged on syringe.
The beneficial effects of the utility model: having increased vibrating device on syringe described in the utility model can, before use by medicine mix homogeneously, prevent from flocking together; Described vibrating device is dismountable is simultaneously arranged on syringe, can facilitate reusing of vibrating device, avoids causing the unnecessary wasting of resources.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, by the specific embodiment of the present utility model is described in detail, will make the technical solution of the utility model and other beneficial effect apparent.
In accompanying drawing,
Fig. 1 is the overall structure schematic diagram of an embodiment of a kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe described in the utility model.
Drawing reference numeral:
1, syringe; 2, piston; 3, piston rod; 4, vibrating device;
41, pallet; 42, spring; 43, metab.
The specific embodiment
Technological means and the effect thereof for further setting forth this utility model, taked, be described in detail below in conjunction with preferred embodiment of the present utility model and accompanying drawing thereof.
Consult Fig. 1, this utility model provides a kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe, comprise syringe 1, be arranged on piston 2 and the piston rod 3 being connected with piston 2 in syringe 1, also comprise the vibrating device 4 for vibration injection device, described vibrating device comprises for blocking the little pallet 41 of injector syringe 1, be arranged on the spring 42 of the below of pallet 41, be fixedly connected on the metab 43 of the relative other end of spring 42.
Dismountable being arranged on syringe of described vibrating device 4.
Described in the present embodiment, on syringe, having increased vibrating device can, before use by medicine mix homogeneously, prevent from flocking together; Described vibrating device is dismountable is simultaneously arranged on syringe, can facilitate reusing of vibrating device, avoids causing the unnecessary wasting of resources.
The above; for the person of ordinary skill of the art; can make other various corresponding changes and distortion according to the technical solution of the utility model and technical conceive, and all these changes and distortion all should belong to the protection domain of this utility model claim.
Claims (2)
1. a vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe, comprises syringe, is arranged on piston and the piston rod being connected with piston in syringe, it is characterized in that, also comprises the vibrating device for vibration injection device; Described vibrating device comprises for blocking the little pallet of injector syringe, is arranged on the spring of the below of pallet, is fixedly connected on the metab of the relative other end of spring.
2. a kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe according to claim 1, is characterized in that, described vibrating device is dismountable to be arranged on syringe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420319160.8U CN203989291U (en) | 2014-06-16 | 2014-06-16 | A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420319160.8U CN203989291U (en) | 2014-06-16 | 2014-06-16 | A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203989291U true CN203989291U (en) | 2014-12-10 |
Family
ID=52029375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420319160.8U Active CN203989291U (en) | 2014-06-16 | 2014-06-16 | A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203989291U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11241330B1 (en) | 2021-04-02 | 2022-02-08 | Brixton Biosciences, Inc. | Apparatus for creation of injectable slurry |
-
2014
- 2014-06-16 CN CN201420319160.8U patent/CN203989291U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11241330B1 (en) | 2021-04-02 | 2022-02-08 | Brixton Biosciences, Inc. | Apparatus for creation of injectable slurry |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Pearson et al. | Prolactin-dependent rat mammary cancer: a model for man? | |
| MX2013000125A (en) | Preservative-free follicle stimulating hormone solution delivery device. | |
| CU24043B1 (en) | RECOMBINANT HUMAN FOLICULATING HORMONE, PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS | |
| CN204147139U (en) | A kind of rat fixing device | |
| JP2013056949A5 (en) | ||
| CN203989291U (en) | A kind of vibratile p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe | |
| CN103340700B (en) | Induction cattle produces the method for double calf | |
| MX2017008000A (en) | Single use injection system. | |
| ZA202204282B (en) | A stable parenteral dosage form of cetrorelix acetate | |
| Knobil | The wisdom of the body revisited | |
| CN203989290U (en) | A kind of p-GLU-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2 sustained-release micro-spheres syringe of Timing | |
| CN205434587U (en) | Medicine administered by injection syringe | |
| CN107079878A (en) | A kind of young and middle-aged woods musk deer the secondary musk secretion method | |
| McCue | Management of seasonal anestrus: Hormone therapy | |
| CN205460260U (en) | Put into warm pressurization atomizing device of dosing | |
| Hilmes | Central Progesterone Involvement in Estrogen-Induced Prolactin and Luteinizing Hormone Secretion Surges in Female Rats | |
| Tramacere et al. | Multivariate analysis of prognostic factors and survival in patients with" glioblastoma multiforme" | |
| Proietto et al. | Progesterone and estradiol modulate gonadotropin-releasing hormone effect over LH surge in the South American Plains Vizcacha, Lagostomus maximus | |
| RU2016124629A (en) | Method for inducing superovulation in embryo donor cows with prolonging the action of pituitary gonadotropins | |
| Narenji Sani et al. | Reproductive performance of Zel ewes with different dosage of eCG outside the natural breeding season | |
| Stein | IgE mediated allergy: case report | |
| Górski et al. | Involvement of salsolinol in the suckling-induced oxytocin surge in sheep | |
| Gonkowski | Somatostatin-like immunoreactive primary sensory neurons supplying the porcine adrenal glands in physiological conditions and after adrenalectomy | |
| Morfoisse et al. | Beneficial effect of estrogen on lymphatic system is inhibited by hormone therapy to promote lymphedema | |
| McCue | 86 Induction of Lactation to Create |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |