CN203874298U - Multi-frequency ultrasonic tumor treatment head - Google Patents
Multi-frequency ultrasonic tumor treatment head Download PDFInfo
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- CN203874298U CN203874298U CN201420317570.9U CN201420317570U CN203874298U CN 203874298 U CN203874298 U CN 203874298U CN 201420317570 U CN201420317570 U CN 201420317570U CN 203874298 U CN203874298 U CN 203874298U
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Abstract
The utility model discloses a multi-frequency ultrasonic tumor treatment head. The multi-frequency ultrasonic tumor treatment head comprises an ultrasonic transducer; the ultrasonic transducer comprises a double-head stud, a rear cover plate, a front cover plate and an insulating sleeve located on a middle section of the double-head stud; and the rear cover plate and the front cover plate are respectively located on front and rear threaded sections of the double-head stud and tightly press an insulating ceramic chip I, a rear piezoelectric ceramic pile, an insulating ceramic chip II, a mass block, an insulating ceramic chip III, a front piezoelectric ceramic pile and an insulating ceramic chip IV which successively sleeve the insulating sleeve. A signal generator is used to emit two signal frequencies, so the two groups of the electric ceramic piles at two ends of the mass block in the transducer generate different-frequency vibrations, the transducer works at a double-frequency mode, a low frequency generated by a difference frequency in the double frequencies is used to enhance a cavitation function, tumor neovasularization is induced to form thrombi, a channel supplying nutrition to tumor is blocked, and a tumor treatment effect is achieved. The multi-frequency ultrasonic tumor treatment head is simple in structure, low in manufacturing cost and easy and convenient to operate.
Description
Technical field
This utility model relates to the technical field of acoustic contrast agent microvesicle cavitation effect treatment tumor, particularly relates to a kind of multiple-frequency supersonic ripple oncotherapy head.
Background technology
Tumor is serious threat human life's major disease, the key element that has become mankind's death because of, at present, the annual cancer patient's number of the infected of China is about 2,500,000, because of cancer mortality number approximately 1,800,000, and presents rejuvenation and ascendant trend year by year.The method of oncotherapy has at present: operative treatment, radiotherapy, chemotherapy, Biotherapeutics, other treatment etc.These Therapeutic Method are difficult to avoid infringement not answer impaired tissue in treatment tumor.Ultrasonic therapeutic tumor, sometimes also referred to as ultrasonic bloodless operation, is a kind for the treatment of technology of non-invasi.Principle is that the cavitation effect of using ultrasound ripple carries out oncotherapy, and this operation does not need to operate on, and skin is injury-free, avoid simultaneously infringement should be not impaired tissue and function.
Early stage ultrasonic therapeutic tumor principle is thermal effect of ultrasound treatment.But the method is mainly the treatment for superficial tumor, for example, the disclosed ultrasound wave therapeutic apparatus for treating tumor of patent " a kind of focused transducer device (CN102580261A) that is applicable to superficial tumor treatment ", comprising: coupling probe shell, treatment piezoelectric ceramic wafer, intracavity Ultrasonic-B probe, can plug medium aluminum, the composition such as sound-absorbing material dorsad.Utilize the thermal effect of ultrasound treatment superficial tumor of ball-type piezoelectric ceramic wafer.
Conventional Therapeutic Method is Low power ultrasound micro-bubble agent treatment tumor now, principle is that position to required treatment is through intravenous injection micro-bubble agent, in the time that tissue blood vessel is poured into by high concentration microvesicle, cavitation nucleus density rolls up, cavitation threshold values reduces, low frequency/small Power ultrasonic causes strong cavitation effect mechanical injuries vascular endothelial cell, basement membrane is exposed, thereby startup intrinsic coagulation system, cause tumor microcirculation thromboembolism blocking-up tumor to supply with the passage of nutrition, reach the effect for the treatment of tumor.Different from normal blood capillary, tumor-microvessel growth causes rapidly structure disturbance, shows as tube wall and lacks flesh layer, and wall is thin and crisp, and permeability is high, so be more easily subject to cavitation damage.The disclosed ultrasonic therapeutic head of patent " ultrasonic therapeutic head and there is the sonicator (CN1754586A) of this treatment head ", comprise: support, the actuating device of piezoelectric chip, support piezoelectric chip, drive piezoelectric chip by actuating device, carry out ultrasonic therapeutic.But this device adopts the working method of single-frequency, and a little less than ultrasonic cavitation effect, oncotherapy efficiency is low.
Studies have shown that the sonochemistry effect of multiple-frequency supersonic is much larger than the ultrasonic sonochemistry effect of single-frequency.Research is found, when multifrequency pattern lower time, to utilize the low frequency that in multifrequency, difference frequency produces can strengthen cavitation.Patent " focused ultrasonic noninvasive sound powered tumor therapy system (CN102233159A) ", comprises ultrasonic diagnosis probe 26 and hemispherical rigidity spherical crown 27.Adopt the concentration ultrasonic of multi-frequency focused transducer transmitting multi-frequency to target tissue, as shown in accompanying drawing 2,3, on hemispherical rigidity spherical crown 27, piezoquartz 28 is organized in equidistant embedding more, the ultrasound wave that described piezoquartz 28 produces pools ultrasound wave and converges focal spot 29, utilizes the principle focusing on to produce multifrequency.The ultrasound wave of only launching at multiple piezoquartzes 28 converges at a bit, and this some place could form multifrequency and be used for the treatment of.When treatment, must carry out three dimensions scanning, scan period length, inefficiency.This device is by organizing equidistant embedding half spherical crown of piezoquartz 28 more, and complex structure requires to manufacture, installation accuracy is high, causes installation cost high.Multi-frequency focusing ultrasonic transducer is arranged on three-dimensional locating support, and the focus focusing on by three-dimensional locating support adjustment multi-frequency ultrasonic transducer when treatment acts on tumor locus and treats, complicated operation.
Utility model content
, complex structure and other problems low according to above-mentioned focused ultrasonic noninvasive sound powered tumor therapy system therapeutic efficiency.The multiple-frequency supersonic ripple oncotherapy head that the efficiency that the utility model discloses a kind of oncotherapy is high, simple in structure, facilitate medical personnel to operate.
The technological means that this utility model adopts is as follows:
A kind of multiple-frequency supersonic ripple oncotherapy head, comprise ultrasonic transducer, described ultrasonic transducer comprises studs, back shroud, front shroud and is positioned at the insulation sleeve on the stage casing of described studs, described back shroud and described front shroud lay respectively on the front and back thread segment of studs, and will be socketed in turn the insulating ceramic film one on described insulation sleeve, rear piezoelectric ceramic stack, insulating ceramic film two, mass, insulating ceramic film three, front piezoelectric ceramic stack, insulating ceramic film four compressions;
Between described rear piezoelectric ceramic stack and described back shroud, be provided with insulating ceramic film one, between described rear piezoelectric ceramic stack and described mass, be provided with insulating ceramic film two;
Between described front piezoelectric ceramic stack and described mass, be provided with insulating ceramic film three, between described front piezoelectric ceramic stack and described front shroud, be provided with insulating ceramic film four;
On described rear piezoelectric ceramic stack, be fixedly connected with electrode slice one, described electrode slice one connects the front/rear end of described rear piezoelectric ceramic stack, and described electrode slice one is provided with the wire one that connects signal generator negative pole;
On described front piezoelectric ceramic stack, be fixedly connected with electrode slice two, described electrode slice two connects the front/rear end of described front piezoelectric ceramic stack, and described electrode slice two is provided with the wire two that connects signal generator negative pole;
Described rear piezoelectric ceramic stack comprise two rear piezoelectric ceramic rings placed side by side and after described two the electrode slice four between piezoelectric ceramic ring, described electrode slice four is provided with the wire four that connects signal generator positive pole;
Described front piezoelectric ceramic stack comprises two front piezoelectric ceramic rings placed side by side and the electrode slice three between described two front piezoelectric ceramic rings, is connected with the wire three that connects signal generator positive pole on described electrode slice three.
Further, also comprise the shell and the gland that hold described ultrasonic transducer, the front end of described shell is provided with the opening one that described ultrasonic transducer passes through, described gland is fixedly connected on described ultrasonic transducer on described opening one through described front shroud, described front shroud is also provided with cap outward, described cap is fixedly connected with described shell at described opening one place, and the rear end of described shell is provided with the opening two that described wire one, described wire two, described wire three and described wire four-way are crossed.
Further, one section of inwall that described shell is positioned at described opening one place is provided with female thread one, the outer wall of described gland is provided with the external screw thread one matching with described female thread one, one section of outer wall that described shell is positioned at described opening one place is provided with external screw thread two, and the inwall of described cap is provided with the female thread two matching with described external screw thread two.
Further, in the internal cavities between described front shroud and described cap, be filled with ultrasound medical couplant.
Further, the material of described back shroud is rustless steel, and the material of described front shroud is aluminium alloy.
Compared with prior art, the utlity model has following beneficial effect:
1, therapeutic efficiency is high
Focused ultrasonic noninvasive sound powered tumor therapy system is that the concentration ultrasonic of multi-frequency focused transducer transmitting multi-frequency is to target tissue, multi-frequency ultrasound wave forms focal spot in same focus, utilize the principle focusing on to produce multifrequency, only could form multifrequency at focal spot place and be used for the treatment of.While adopting focused ultrasonic noninvasive sound powered tumor therapy system treatment, must carry out three dimensions scanning, could realize tumor vascular cavitation effect mechanical injuries, blocking-up tumor is supplied with the passage of nutrition, reaches the effect for the treatment of tumor.Therefore, the scan period of this Therapeutic Method length, inefficiency.
The multiple-frequency supersonic ripple oncotherapy head that this utility model is announced, adopts multiple ultrasound wave of launching in same direction, all produces multifrequency effect on the straight line of transmit direction.When the multiple-frequency supersonic ripple oncotherapy head that adopts this utility model to announce carries out oncotherapy, need not consider the distance for the treatment of head in ultrasound emission direction, only need in a plane perpendicular to ultrasound emission direction, carry out two-dimensional scan, just can realize the treatment of tumor.Therefore it is short that it treats scan period, and therapeutic efficiency improves greatly.
2, simple in structure, cost is low
The multi-frequency focused transducer that focused ultrasonic noninvasive sound powered tumor therapy system adopts is organized the hyperacoustic piezoquartz of transmitting different frequency in the same half equidistant embedding in spherical crown same plane position more, the piezoquartz of every group of same frequency is equidistantly arranged at same spherical crown same plane, will produce multi-frequency ultrasound wave and form focal spot in same focus, utilize the principle focusing on to produce multifrequency.Described piezoquartz is in fact ultrasonic transducer, is made up of cover plate, piezoelectric ceramic stack etc., and this structure needs multiple piezoquartzes at the same half equidistant installation in spherical crown same plane position, complex structure.Hemispherical rigidity spherical crown processing difficulties, manufacturing cost is high.Because focused ultrasonic noninvasive sound powered tumor therapy system focuses on the operation principle that realizes multifrequency, require installation accuracy high, greatly raise the cost.
Multiple-frequency supersonic ripple oncotherapy head is made up of two groups of piezoelectric ceramic stacks, produces respectively the vibration of different frequency.In the time that frequency generator is connected simultaneously, two groups of piezoelectric ceramic stacks are worked simultaneously, produce two groups of ultrasound wave that mutually superpose, and form multifrequency effect.This structure is equivalent to the rod shaped structure that two ultrasonic transducers are composed in series, simple in structure.
Because multiple-frequency supersonic ripple oncotherapy head is simple in structure than multi-frequency focused transducer, manufacturing cost reduces.
3, simple, convenient
In focused ultrasonic noninvasive sound powered tumor therapy system, the three-dimensional locating support of multi-frequency focusing ultrasonic transducer adjustment is treated focal spot alignment targets tissue.Multi-frequency focusing ultrasonic transducer is arranged on three-dimensional locating support, arc support is made up of arc frame and bracing frame, arc frame is by bracing frame support, focused transducer relies on the slide block collar to be connected with slide block, slide block is fixed on arc frame, and can on arc frame, move freely, when work, need to carry out three dimensions scanning, the focus focusing on by three-dimensional locating support adjustment multi-frequency ultrasonic transducer acts on tumor locus and treats.Therefore, when treatment, need to adjust three-dimensional locating support, complicated operation.
In the ultrasonic propagation direction that this utility model multiple-frequency supersonic ripple oncotherapy head produces, a line optional position is all multiple-frequency supersonic ripples.When treatment, need not consider the distance for the treatment of head in ultrasound emission direction, only need in a plane perpendicular to ultrasound emission direction, carry out two-dimensional scan, the multiple-frequency supersonic ripple of a line of multiple-frequency supersonic ripple oncotherapy head generation reaches tumor site and effectively treats.Medical personnel are hand-held can be treated, simple, convenient.
This utility model can extensively be promoted in fields such as acoustic contrast agent microvesicle cavitation effect treatment tumors for the foregoing reasons.
Brief description of the drawings
Below in conjunction with the drawings and specific embodiments, this utility model is described in further detail.
Fig. 1 is the generalized section of a kind of multiple-frequency supersonic ripple oncotherapy head of the present utility model.
Fig. 2 is the tangent plane schematic diagram of multi-frequency focusing transducer.
Fig. 3 is the plane structure chart of multi-frequency focusing transducer.
In Fig. 1,1, shell, 2, wire one, 3, wire two, 4, back shroud, 5, insulating ceramic film one, 6, electrode slice one, 7, rear piezoelectric ceramic stack, 8, insulating ceramic film two, 9, mass, 10, insulating ceramic film three, 11, electrode slice two, 12, front shroud, 13, cap, 14, gland, 15, insulating ceramic film four, 16, electrode slice three, 17, front piezoelectric ceramic stack, 18, electrode slice four, 19, insulation sleeve, 20, bolt, 21, wire three, 22, wire four, 23, opening one, 24, opening two, 25, spacing round platform.
In Fig. 2,3,26, ultrasonic diagnosis probe, 27, hemispherical rigidity spherical crown, 28, piezoquartz, 29, ultrasound wave converges focal spot.
Detailed description of the invention
As shown in Figure 1, a kind of multiple-frequency supersonic ripple oncotherapy head, comprise ultrasonic transducer, described ultrasonic transducer entirety becomes cylindrical structural, described ultrasonic transducer comprises studs 20, back shroud 4, front shroud 12 and be positioned at the insulation sleeve 19 on the stage casing of described studs 20, described back shroud 4 and described front shroud 12 lay respectively on the front and back thread segment of studs 20, and the insulating ceramic film 1 on described insulation sleeve 19 will be coaxially socketed in turn, rear piezoelectric ceramic stack 7, insulating ceramic film 28, mass 9, insulating ceramic film 3 10, front piezoelectric ceramic stack 17, insulating ceramic film 4 15 compresses,
Between described rear piezoelectric ceramic stack 7 and described back shroud 4, be provided with insulating ceramic film 1, between described rear piezoelectric ceramic stack 7 and described mass 9, be provided with insulating ceramic film 28; Between described front piezoelectric ceramic stack 17 and described mass 9, be provided with insulating ceramic film 3 10, between described front piezoelectric ceramic stack 17 and described front shroud 12, be provided with insulating ceramic film 4 15;
One end that described front shroud 12 contacts with described insulating ceramic film 4 15 is provided with spacing round platform 25;
Described ultrasonic transducer also comprises the shell 1 and the gland 14 that hold described ultrasonic transducer, the front end of described shell 1 is provided with the opening 1 that described ultrasonic transducer passes through, described gland 12 passes described front shroud 12 and matches with the described spacing round platform 25 on described front shroud 12, described ultrasonic transducer is threaded connection on described opening 1, described front shroud 12 is outer is also provided with cap 13, and described cap 13 is threaded with described shell 1 at described opening one 23 places;
On described rear piezoelectric ceramic stack 7, be fixedly connected with electrode slice 1, described electrode slice 1 connects the front/rear end of described rear piezoelectric ceramic stack 7, and described electrode slice 1 is provided with the wire 1 that connects signal generator negative pole;
On described front piezoelectric ceramic stack 17, be fixedly connected with electrode slice 2 11, described electrode slice 2 11 connects the front/rear end of described front piezoelectric ceramic stack 17, and described electrode slice 2 11 is provided with the wire 22 that connects signal generator negative pole;
Described rear piezoelectric ceramic stack 7 comprise two rear piezoelectric ceramic rings placed side by side and after described two the electrode slice 4 18 between piezoelectric ceramic ring, described electrode slice 4 18 is provided with the wire 4 21 that connects signal generator positive pole;
Described front piezoelectric ceramic stack 17 comprises two front piezoelectric ceramic rings placed side by side and the electrode slice 3 16 between described two front piezoelectric ceramic rings, is connected with the wire 3 22 that connects signal generator positive pole on described electrode slice 3 16.
The rear end of described shell 1 is provided with the opening 2 24 that described wire 1, described wire 22, described wire 3 22 and described wire 4 21 pass through.
In internal cavities between described front shroud 12 and described cap 8, be filled with ultrasound medical couplant.
Described back shroud 4 is chosen the rustless steel that density is larger, makes ultrasound wave be difficult for radiation, strengthens hyperacoustic reflection.Described front shroud 12 is chosen the aluminium alloy that density is less, makes the easy radiation of ultrasound wave.The density of described back shroud 4 is greater than the density of described front shroud 12, and the ultrasound wave that two groups of piezoelectric ceramic stacks produce is propagated to described front shroud 12 1 sides, reduces the ultrasound wave that part is propagated to back shroud direction.
While using the treatment of multiple-frequency supersonic ripple oncotherapy head, wire 21 is connected a kind of frequency of signal generator positive wire 3 and is connected negative pole, wire 22 is connected another frequency of signal generator positive wire 2 and is connected negative pole, while connection simultaneously, front piezoelectric ceramic stack 17 carries out work with rear piezoelectric ceramic stack 7 simultaneously, i.e. described multifrequency work.In the time being operated under multifrequency pattern, utilize the low frequency that in multifrequency, difference frequency produces can strengthen cavitation.The hand-held multiple-frequency supersonic ripple of medical personnel oncotherapy head is aimed at tumor site and is treated.
The above; it is only preferably detailed description of the invention of this utility model; but protection domain of the present utility model is not limited to this; any be familiar with those skilled in the art this utility model disclose technical scope in; be equal to replacement or changed according to the technical solution of the utility model and utility model design thereof, within all should being encompassed in protection domain of the present utility model.
Claims (5)
1. a multiple-frequency supersonic ripple oncotherapy head, it is characterized in that, comprise ultrasonic transducer, described ultrasonic transducer comprises studs (20), back shroud (4), front shroud (12) and be positioned at the insulation sleeve (19) on the stage casing of described studs (20), described back shroud (4) and described front shroud (12) lay respectively on the front and back thread segment of studs (20), and will be socketed in turn the insulating ceramic film one (5) on described insulation sleeve (19), rear piezoelectric ceramic stack (7), insulating ceramic film two (8), mass (9), insulating ceramic film three (10), front piezoelectric ceramic stack (17), insulating ceramic film four (15) compresses,
Between described rear piezoelectric ceramic stack (7) and described back shroud (4), be provided with insulating ceramic film one (5), between described rear piezoelectric ceramic stack (7) and described mass (9), be provided with insulating ceramic film two (8);
Between described front piezoelectric ceramic stack (17) and described mass (9), be provided with insulating ceramic film three (10), between described front piezoelectric ceramic stack (17) and described front shroud (12), be provided with insulating ceramic film four (15);
On described rear piezoelectric ceramic stack (7), be fixedly connected with electrode slice one (6), described electrode slice one (6) connects the front/rear end of described rear piezoelectric ceramic stack (7), and described electrode slice one (6) is provided with the wire one (3) that connects signal generator negative pole;
On described front piezoelectric ceramic stack (17), be fixedly connected with electrode slice two (11), described electrode slice two (11) connects the front/rear end of described front piezoelectric ceramic stack (17), and described electrode slice two (11) is provided with the wire two (2) that connects signal generator negative pole;
Described rear piezoelectric ceramic stack (7) comprise two rear piezoelectric ceramic rings placed side by side and after described two the electrode slice four (18) between piezoelectric ceramic ring, described electrode slice four (18) is provided with the wire four (21) that connects signal generator positive pole;
Described front piezoelectric ceramic stack (17) comprises two front piezoelectric ceramic rings placed side by side and the electrode slice three (16) between described two front piezoelectric ceramic rings, is connected with the wire three (22) that connects signal generator positive pole on described electrode slice three (16).
2. a kind of multiple-frequency supersonic ripple oncotherapy head according to claim 1, it is characterized in that: also comprise the shell (1) and the gland (14) that hold described ultrasonic transducer, the front end of described shell (1) is provided with the opening one (23) that described ultrasonic transducer passes through, described gland (12) is fixedly connected on described ultrasonic transducer on described opening one (23) through described front shroud (12), the outer cap (13) that is also provided with of described front shroud (12), described cap (13) is located to be fixedly connected with described shell (1) at described opening one (23), the rear end of described shell (1) is provided with described wire one (3), described wire two (2), the opening two (24) that described wire three (22) and described wire four (21) pass through.
3. a kind of multiple-frequency supersonic ripple oncotherapy head according to claim 2, it is characterized in that: described shell (1) is positioned at one section of inwall that described opening one (23) locates and is provided with female thread one, the outer wall of described gland (9) is provided with the external screw thread one matching with described female thread one, described shell (1) is positioned at one section of outer wall that described opening one (23) locates and is provided with external screw thread two, and the inwall of described cap (8) is provided with the female thread two matching with described external screw thread two.
4. a kind of multiple-frequency supersonic ripple oncotherapy head according to claim 2, is characterized in that: in the internal cavities between described front shroud (12) and described cap (8), be filled with ultrasound medical couplant.
5. according to a kind of multiple-frequency supersonic ripple oncotherapy head described in the arbitrary claim of claim 1 to 4, it is characterized in that: the material of described back shroud (4) is rustless steel, the material of described front shroud (12) is aluminium alloy.
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| CN201420317570.9U CN203874298U (en) | 2014-06-13 | 2014-06-13 | Multi-frequency ultrasonic tumor treatment head |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104001277A (en) * | 2014-06-13 | 2014-08-27 | 大连交通大学 | Complex frequency ultrasonic tumor treatment head |
| CN108875143A (en) * | 2018-05-25 | 2018-11-23 | 大连交通大学 | A kind of design method of Ni-P bath system |
| CN111844491A (en) * | 2020-07-25 | 2020-10-30 | 黎明职业大学 | Improved complex frequency numerical control ultrasonic machining method and numerical control machining machine tool |
-
2014
- 2014-06-13 CN CN201420317570.9U patent/CN203874298U/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104001277A (en) * | 2014-06-13 | 2014-08-27 | 大连交通大学 | Complex frequency ultrasonic tumor treatment head |
| CN104001277B (en) * | 2014-06-13 | 2017-02-01 | 大连交通大学 | Complex frequency ultrasonic tumor treatment head |
| CN108875143A (en) * | 2018-05-25 | 2018-11-23 | 大连交通大学 | A kind of design method of Ni-P bath system |
| CN108875143B (en) * | 2018-05-25 | 2022-02-22 | 大连交通大学 | Design method of chemical composite plating tank system |
| CN111844491A (en) * | 2020-07-25 | 2020-10-30 | 黎明职业大学 | Improved complex frequency numerical control ultrasonic machining method and numerical control machining machine tool |
| CN111844491B (en) * | 2020-07-25 | 2021-10-08 | 黎明职业大学 | Improved complex frequency numerical control ultrasonic machining method and numerical control machining machine tool |
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