CN203833930U - Filter system of p-hydroxy phenylglycine - Google Patents
Filter system of p-hydroxy phenylglycine Download PDFInfo
- Publication number
- CN203833930U CN203833930U CN201420105168.4U CN201420105168U CN203833930U CN 203833930 U CN203833930 U CN 203833930U CN 201420105168 U CN201420105168 U CN 201420105168U CN 203833930 U CN203833930 U CN 203833930U
- Authority
- CN
- China
- Prior art keywords
- output terminal
- pump
- ultra
- filtration unit
- output end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LJCWONGJFPCTTL-UHFFFAOYSA-N 4-hydroxyphenylglycine Chemical compound OC(=O)C(N)C1=CC=C(O)C=C1 LJCWONGJFPCTTL-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 42
- 238000006243 chemical reaction Methods 0.000 claims description 28
- 239000012528 membrane Substances 0.000 claims description 23
- 239000007788 liquid Substances 0.000 claims description 17
- 238000001914 filtration Methods 0.000 claims description 16
- 238000011001 backwashing Methods 0.000 claims description 2
- 238000011010 flushing procedure Methods 0.000 claims description 2
- 239000011148 porous material Substances 0.000 claims description 2
- 241000894006 Bacteria Species 0.000 abstract description 15
- 238000000034 method Methods 0.000 abstract description 8
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 5
- 238000005265 energy consumption Methods 0.000 abstract description 4
- 239000001963 growth medium Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 3
- 238000007599 discharging Methods 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 description 10
- 239000012535 impurity Substances 0.000 description 4
- 239000000919 ceramic Substances 0.000 description 3
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 239000003456 ion exchange resin Substances 0.000 description 2
- 229920003303 ion-exchange polymer Polymers 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 230000003245 working effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000012847 fine chemical Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The utility model relates to the medical processing field and specifically relates to a filter system of p-hydroxy phenylglycine. The filter system comprises a material tank, a first pump, a cartridge filter and a converter tank, wherein the input end of the first pump is connected with the output end of the material tank; the output end of the first pump is connected with the input end of the cartridge filter; the output end of the cartridge filter is connected with an ultra-filtration unit group; the ultra-filtration unit group comprises two permeated liquor output ends and two concentrated liquor output ends; the first output end of the permeated liquor is communicated with an inferior processing pipeline; the second output end of the permeated liquor is communicated with a first external discharging pipeline; the first output end of the concentrated liquor is connected with the input end of the converter tank; the second output end of the concentrated liquor is communicated with a second external discharging pipeline; the output end of the converter tank is connected with the material tank. By adopting the process, bacteria are firstly concentrated to remove bacterial culture medium, and transfer liquor is secondly clarified to remove bacteria and suspended solids, so that energy consumption is also effectively lowered and cost is reduced while production efficiency is improved.
Description
Technical field
The utility model relates to medical manufacture field, is specifically related to a kind of filtering system of D-pHPG.
Background technology
D-pHPG is a kind of for medical fine chemicals, its traditional complete processing mainly: fermentation using bacteria → conversion → Plate Filtration → ion exchange resin → activated carbon decolorizing → evaporation concentration → crystallization → dry → finished product packing.While adopting above-mentioned traditional technology, because the mixed degree of the conversion fluid after Plate Filtration is high, cause the rate of utilization of ion exchange resin low, finally cause the productive rate of D-pHPG low.For improving the production efficiency of D-pHPG, the method that enterprise adopts is at present to change Investigation on Plate Filtration into ceramic membrane filter, although adopt ceramic membrane filter can concentrate bacterium, conversion fluid is clarified, improve the production efficiency of D-pHPG, but there are following two defects: the one, power consumption is high, and cost of investment is large; The 2nd, film easily stops up, and work-ing life is low.
Utility model content
The purpose of this utility model is to be to provide the filtering system that a kind of production efficiency is high, can effectively reduce the D-pHPG of energy consumption, minimizing cost.
For achieving the above object, the technical solution adopted in the utility model is: a kind of filtering system of D-pHPG, comprise batch can, the first pump, cartridge filter and conversion tank, the input terminus of the first described pump connects the output terminal of batch can, the first delivery side of pump connects the input terminus of cartridge filter, the output terminal of described cartridge filter connects ultra filtration unit, described ultra filtration unit group comprises that two see through liquid output terminal and two concentrated solution output terminals, the first output terminal and the next stage that see through liquid are processed pipeline connection, the second output terminal that sees through liquid is communicated with the first outer row pipeline, the first output terminal of concentrated solution is connected with the input terminus of conversion tank, the second output terminal of concentrated solution is communicated with the second outer row pipeline, the output terminal of conversion tank is connected with batch can.
The beneficial effects of the utility model are: first inoculum is through ultra filtration unit group, remove bacteria culture medium, increase the storage capacity of bacterium, improve the transformation efficiency of bacterium in conversion process, reduce the foreign matter content in conversion fluid, then the bacterium after purifying enters and in conversion tank, carries out conversion reaction, in the time that conversion completes, the conversion fluid obtaining enters in ultra filtration unit group again, remove bacterium and suspended impurity in conversion fluid, conversion fluid is clarified, be convenient to the carrying out of next step operation, adopt this technique, in improving D-pHPG production efficiency, effectively reduce again energy consumption, reduce cost.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
Embodiment
A kind of filtering system of D-pHPG, comprise batch can 10, the first pump 20, cartridge filter 30 and conversion tank 50, the input terminus of the first described pump 20 connects the output terminal of batch can 10, the output terminal of the first pump 20 connects the input terminus of cartridge filter 30, the output terminal of described cartridge filter 30 connects ultra filtration unit group, described ultra filtration unit group comprises that two see through liquid output terminal and two concentrated solution output terminals, the first output terminal that sees through liquid is communicated with next stage processing pipeline 44, the second output terminal that sees through liquid is communicated with the first outer row pipeline 47, the first output terminal of concentrated solution is connected with the input terminus of conversion tank 50, the second output terminal of concentrated solution is communicated with the second outer row pipeline 46, the output terminal of conversion tank 50 is connected with batch can 10, in actual device, can connection that valve realizes each path be set and close seeing through the output terminal of liquid and the output terminal of concentrated solution.
Principle of work of the present utility model is: in batch can 10, put into inoculum to be processed, be delivered to after cartridge filter 30 carries out primary filter and directly enter ultra filtration unit group through the first pump 20, the bacterium concentrated solution of ultra filtration unit group enters conversion tank 50, see through liquid and enter the first outer row pipeline 47, after bacterium concentrated solution has transformed in conversion tank 50, conversion fluid moves in batch can 10, and then enter ultra filtration unit group, ultra filtration unit group concentrated solution enters the second outer row pipeline 46, sees through liquid and enters next stage processing pipeline 44.Adopt this technique, ultra filtration unit group possesses two functions, and one is that the bacterium in batch can 10 is concentrated, deviates from substratum, and this process increases the viability of bacterium, reduces substratum and has increased the transformation efficiency of bacterium in conversion process; Another is in the time having transformed, conversion fluid is transferred in batch can 10, remove bacterium and the suspended impurity in conversion fluid by ultra filtration unit group, this process can be clarified conversion fluid, be convenient to next step purifying, the utility model, in improving D-pHPG production efficiency, has effectively reduced again energy consumption, has reduced cost.
Further, as shown in Figure 1, described ultra filtration unit group comprises ultra filtration unit 40, ultra filtration unit 40 comprises the second pump 41 and ultra-filtration membrane device 42, the input terminus of the second pump 41 is connected with the output terminal of cartridge filter 30, the output terminal of the second pump 41 is connected with the input terminus of ultra-filtration membrane device 42, liquid output terminal and the next stage processing pipeline 44 that sees through of ultra-filtration membrane device 42 is communicated with or enters outer row pipeline 47, and the concentrated solution output terminal of ultra-filtration membrane device 42 is connected with the input terminus of conversion tank 50 or enters outer row pipeline 46.
Further, the membrane element in described ultra filtration unit group is the tubular ultra-filtration membrane device that can bear the following back flushing of 0.9Bar.
Further, the filtering accuracy of described cartridge filter 30 is 50～100 μ m.Suspended particle, impurity etc. in feed liquid can be trapped in the cartridge surface and hole of cartridge filter 30 like this, for the steady running of postorder ultra filtration unit group is given security, avoid the membrane element in ultra filtration unit group to stop up simultaneously, be conducive to extend the work-ing life of membrane element.
Further, the pore size of the membrane element in described ultra filtration unit group is 20-300nm.
Further, described ultra filtration unit 40 also comprises the 3rd pump 43, the 3rd described pump 43 is backwashing pumps, and the output terminal of the 3rd pump 43 is connected with the liquid output terminal that sees through of ultra-filtration membrane device 42 by backflushing pipe 45, when actual use, backwash water enters membrane element by the 3rd pump 43 by backflushing pipe 45, impurity, by the outer row of outer row pipeline 46, recoils out by the tamper of membrane element by backwash, than more anti-pollution of ceramic membrane, longer service life is more stable.
Claims (6)
1. the filtering system of a D-pHPG, it is characterized in that: comprise batch can (10), the first pump (20), cartridge filter (30) and conversion tank (50), the input terminus of described the first pump (20) connects the output terminal of batch can (10), the output terminal of the first pump (20) connects the input terminus of cartridge filter (30), the output terminal of described cartridge filter (30) connects ultra filtration unit group, described ultra filtration unit group comprises that two see through liquid output terminal and two concentrated solution output terminals, the first output terminal that sees through liquid is communicated with next stage processing pipeline (44), the second output terminal that sees through liquid is communicated with the first outer row pipeline (47), the first output terminal of concentrated solution is connected with the input terminus of conversion tank (50), the second output terminal of concentrated solution is communicated with the second outer row pipeline (46), the output terminal of conversion tank (50) is connected with batch can (10).
2. the filtering system of D-pHPG according to claim 1, it is characterized in that: described ultra filtration unit group comprises ultra filtration unit (40), ultra filtration unit (40) comprises the second pump (41) and ultra-filtration membrane device (42), the input terminus of the second pump (41) is connected with the output terminal of cartridge filter (30), the output terminal of the second pump (41) is connected with the input terminus of ultra-filtration membrane device (42), liquid output terminal and the next stage processing pipeline (44) that sees through of ultra-filtration membrane device (42) is communicated with or enters outer row pipeline (47), the concentrated solution output terminal of ultra-filtration membrane device (42) is connected with the input terminus of conversion tank (50) or enters outer row pipeline (46).
3. the filtering system of D-pHPG according to claim 1 and 2, is characterized in that: the membrane element in described ultra filtration unit group is the tubular ultra-filtration membrane device that can bear the following back flushing of 0.9Bar.
4. the filtering system of D-pHPG according to claim 1 and 2, is characterized in that: the filtering accuracy of described cartridge filter (30) is 50～100 μ m.
5. the filtering system of D-pHPG according to claim 1 and 2, is characterized in that: the pore size of the membrane element in described ultra filtration unit group is 20-300nm.
6. the filtering system of D-pHPG according to claim 2, it is characterized in that: described ultra filtration unit (40) also comprises the 3rd pump (43), the 3rd described pump (43) is backwashing pump, and the output terminal of the 3rd pump (43) is connected with the liquid output terminal that sees through of ultra-filtration membrane device (42) by backflushing pipe (45).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420105168.4U CN203833930U (en) | 2014-03-07 | 2014-03-07 | Filter system of p-hydroxy phenylglycine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420105168.4U CN203833930U (en) | 2014-03-07 | 2014-03-07 | Filter system of p-hydroxy phenylglycine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203833930U true CN203833930U (en) | 2014-09-17 |
Family
ID=51511798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420105168.4U Expired - Lifetime CN203833930U (en) | 2014-03-07 | 2014-03-07 | Filter system of p-hydroxy phenylglycine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203833930U (en) |
-
2014
- 2014-03-07 CN CN201420105168.4U patent/CN203833930U/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140917 |