CN203700242U - Device for collecting animal parotid saliva - Google Patents
Device for collecting animal parotid saliva Download PDFInfo
- Publication number
- CN203700242U CN203700242U CN201320875886.5U CN201320875886U CN203700242U CN 203700242 U CN203700242 U CN 203700242U CN 201320875886 U CN201320875886 U CN 201320875886U CN 203700242 U CN203700242 U CN 203700242U
- Authority
- CN
- China
- Prior art keywords
- fistula
- parotid
- animal
- tubing
- collecting bag
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241001465754 Metazoa Species 0.000 title claims abstract description 34
- 210000003296 saliva Anatomy 0.000 title abstract description 24
- 206010016717 Fistula Diseases 0.000 claims abstract description 39
- 230000003890 fistula Effects 0.000 claims abstract description 39
- 206010036790 Productive cough Diseases 0.000 claims description 24
- 210000003802 sputum Anatomy 0.000 claims description 24
- 208000024794 sputum Diseases 0.000 claims description 24
- 210000000214 mouth Anatomy 0.000 abstract description 8
- 238000005516 engineering process Methods 0.000 abstract description 4
- 238000001802 infusion Methods 0.000 abstract 4
- 210000003681 parotid gland Anatomy 0.000 description 9
- 238000000034 method Methods 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 229920000742 Cotton Polymers 0.000 description 5
- 238000011109 contamination Methods 0.000 description 5
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 description 3
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000009261 transgenic effect Effects 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 210000005075 mammary gland Anatomy 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical compound C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- QCHFTSOMWOSFHM-UHFFFAOYSA-N SJ000285536 Natural products C1OC(=O)C(CC)C1CC1=CN=CN1C QCHFTSOMWOSFHM-UHFFFAOYSA-N 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000001460 masseteric effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 229960001416 pilocarpine Drugs 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a device for collecting animal parotid saliva. The device comprises a collecting bag, a collecting pipe communicated with inside of the collecting bag and a release plug formed at the bottom of the collecting bag, wherein a fistula is connected with the top end of the collecting pipe; the fistula comprises two infusion tubes which are arranged side by side; upper parts of the two infusion tubes are branched and lower parts are connected in a manner of closely attaching. According to the device for collecting the animal parotid saliva disclosed by the utility model, by respectively inserting two infusion tubes which are arranged on the fistula which is connected to the collecting pipe side by side into an oral cavity near end and a parotid near end of an animal parotid duct, saliva enters into the collecting bag through the infusion tube at the parotid near end, and the parotid saliva in the collecting bag can be taken out in one time by opening the release plug at the bottom of the collecting bag; the collecting device can collect the parotid saliva for long time in a manner of isolating from external side to avoid pollution; the utility model is applicable to the field of the bioengineering technology.
Description
Technical field
The utility model relates to technical field of bioengineering, particularly relate to a kind of collect animal parotid sputum device.
Background technology
Along with the development of transgenic technology, utilize transgenic animal to produce pharmaceutical protein, in the mammary gland of transgenic animal, be particularly the most successful, but exist equally deficiency.For example only have jenny could in mammary gland, express pharmaceutical protein, and give milk and will just can carry out in certain season or time, these shortcomings all hamper the development of galactophore biological reactor.
At present, utilize parotid gland specificity promoter, express foreign protein technology and also succeed in the parotid gland of domestic animal, compared with galactophore biological reactor, parotid gland bio-reactor has many advantages: 1, there is no gender difference; 2, not free difference; 3, animal is collected purifying protein after not needing sexual maturity mating by the time to give milk, and has shortened the time that obtains recombinant protein; 4, in parotid sputum, protein ingredient is few, the easy separation and purification of recombinant protein.
Will be from parotid sputum purification of recombinant proteins, just must have a kind of can a large amount of methods of collecting free of contamination parotid sputum steady in a long-term.In current saliva collection method, only have fistula modus operandi could meet this demand, but up to the present all there is no a set of collection device easily and effectively.
The method of existing collection domestic animals saliva mainly contains: one is by Animal Anesthesia, injection pilocarpine, induced animal salivates, then directly draw saliva from parotid gland opening part, this method needs each collection saliva all will anaesthetize fixing animal, waste time and energy, and the saliva gathering is measured unstable and is easily polluted by other materials in oral cavity; Another kind is that cotton or cotton cord are put into animal mouth, allows it chew after for some time, by the saliva extruding on cotton or cotton cord or by centrifugation out, the saliva that this method is collected is to mix saliva, and the amount of collection is considerably less; Also having one is fistula modus operandi, from masseteric muscle forward position, lower jaw separate SD, insert conduit toward parotid gland direction, thereby by parotid sputum drainage out, this method can be collected a large amount of free of contamination parotid sputums, but nursing is more difficult during collecting, and easily causes fistula to be pulled out, and cause saliva waste while not collecting saliva.
Utility model content
For addressing the above problem, the utility model provides a kind of device of a large amount of free of contamination collection animal parotid sputums lastingly.
The utility model solves the technical scheme that its technical problem adopts:
A kind of device of collecting animal parotid sputum, the collection tube that comprises collecting bag, communicate with collecting bag inside and be arranged at the release plug mouth of collecting bag bottom, be connected and be provided with fistula with the top of collection tube, fistula comprises the tubing that twice are arranged side by side, and two tubing top bifurcateds, bottom are close to connected.
Be further used as the improvement of technical solutions of the utility model, the bottom of two tubing upper bifurcation parts is equipped with the groove around tubing.
Be further used as the improvement of technical solutions of the utility model, two tubings along its length internal diameter are consistent, and the external diameter of two tubings increases gradually from the connecting portion of inlet end to two tubing.
Be further used as the improvement of technical solutions of the utility model, on fistula, the connected position of two tubings external diameter is in the same size, on fistula, increases gradually from two tubing bifurcation to bottom internal diameters.
Be further used as the improvement of technical solutions of the utility model, be arranged with a circle and have the projection of back-off part outside the top of collection tube, projection embeds in fistula carries out airtight connection.
Be further used as the improvement of technical solutions of the utility model, be also provided with the fistula joint that can be installed on fistula bottom, the both sides of fistula joint bottom communicate.
Be further used as the improvement of technical solutions of the utility model, collecting bag is provided with handle.
The beneficial effects of the utility model: this device of collecting animal parotid sputum inserts respectively nearly buccal and the nearly parotid gland end of animal SD by two tubings arranged side by side on the fistula being connected with collection tube, saliva enters in collecting bag through the tubing of nearly parotid gland end, the release plug mouth of opening collecting bag bottom gets final product the parotid sputum in disposable taking-up collecting bag, and this collection device can the long-time and free of contamination collection of carrying out parotid sputum that is hedged off from the outer world.
Brief description of the drawings
Below in conjunction with accompanying drawing, the utility model is described in further detail:
Fig. 1 is the utility model embodiment one-piece construction schematic diagram;
Fig. 2 is fistula and fistula connector matching structure schematic diagram in the utility model embodiment;
Fig. 3 is the utility model collection tube top syndeton schematic diagram.
Embodiment
With reference to Fig. 1～Fig. 3, the utility model is a kind of device of collecting animal parotid sputum, the collection tube 2 that comprises collecting bag 1, communicate with collecting bag 1 inside and the release plug mouth 3 that is arranged at collecting bag 1 bottom, be connected and be provided with fistula 4 with the top of collection tube 2, fistula 4 comprises the tubing that twice are arranged side by side, and two tubing top bifurcateds, bottom are close to connected.
This device of collecting animal parotid sputum inserts respectively nearly buccal and the nearly parotid gland end of animal SD by two tubings arranged side by side on the fistula 4 being connected with collection tube 2, saliva enters in collecting bag 1 through the tubing of nearly parotid gland end, open the release plug mouth 3 of the collecting bag 1 bottom parotid sputum in can disposable taking-up collecting bag, this collection device can the long-time and free of contamination collection of carrying out parotid sputum that is hedged off from the outer world.
As the utility model preferred embodiment, the bottom of two tubing upper bifurcation parts is equipped with the groove 41 around tubing.
After two tubings are connected with the SD in animal body, can tighten at groove 41 positions fixingly to tubing with medical cotton thread, prevent that fistula 4 is pulled out.
As the utility model preferred embodiment, two tubings along its length internal diameter are consistent, and the external diameter of two tubings increases gradually from the connecting portion of inlet end to two tubing.
As the utility model preferred embodiment, on fistula 4, the connected position of two tubings external diameter is in the same size, on fistula 4, increases gradually from two tubing bifurcation to bottom internal diameters.
As the utility model preferred embodiment, be arranged with a circle and have the projection 22 of back-off part 21 outside the top of collection tube 2, projection 22 embeds in fistulas 4 carries out airtight connection.
As the utility model preferred embodiment, be also provided with the fistula joint 5 that can be installed on fistula 4 bottoms, the both sides of fistula joint 5 bottoms communicate.
Without undertaken by collecting bag 1 parotid sputum collect time, fistula 4 can be separated with collection tube 2, fistula joint 5 is inserted in to the tail end of fistula 4, thereby the tubing of fistula 4 both sides forms backflow, make the saliva of animal secretion can be back to again oral cavity, avoided causing waste in the time not collecting saliva.
As the utility model preferred embodiment, collecting bag 1 is provided with handle 6.
Collecting bag 1 is provided with a handle 6, collecting bag 1 can be hung on it animal, animal capable is freely walked, or in the time that restriction animal freely walks, collecting bag 1 is hung on hurdle, on collecting bag 1, have containing mark, the saliva volume that energy measurement collection arrives, there is outlet collecting bag 1 below, while collecting saliva, outlet is covered, when collection saliva is complete, open outlet, saliva can be transferred in other receiving flasks that can preserve for a long time.
Certainly, the invention is not limited to above-mentioned embodiment, those of ordinary skill in the art also can make equivalent variations or replacement under the prerequisite without prejudice to the utility model spirit, and the modification that these are equal to or replacement are all included in the application's claim limited range.
Claims (7)
1. collect the device of animal parotid sputum for one kind, it is characterized in that: the collection tube (2) that comprise collecting bag (1), communicates with described collecting bag (1) inside and be arranged at the release plug mouth (3) of described collecting bag (1) bottom, be connected and be provided with fistula (4) with the top of described collection tube (2), described fistula (4) comprises the tubing that twice are arranged side by side, and described in two, tubing top bifurcated, bottom are close to connected.
2. the device of collection animal parotid sputum according to claim 1, is characterized in that: described in two, the bottom of tubing upper bifurcation part is equipped with the groove (41) around tubing.
3. the device of collection animal parotid sputum according to claim 1 and 2, is characterized in that: described in two, internal diameter is consistent along its length for tubing, and described in two, the external diameter of tubing increases gradually from the connecting portion of inlet end to two tubing.
4. the device of collection animal parotid sputum according to claim 1 and 2, is characterized in that: the connected position of upper two tubings of described fistula (4) external diameter is in the same size, and described fistula (4) is upper to be increased gradually from two tubing bifurcation to bottom internal diameters.
5. the device of collection animal parotid sputum according to claim 1 and 2, it is characterized in that: outside the top of described collection tube (2), be arranged with the projection (22) that a circle has back-off part (21), described projection (22) embeds in fistula (4) carries out airtight connection.
6. the device of collection animal parotid sputum according to claim 5, is characterized in that: be also provided with the fistula joint (5) that can be installed on described fistula (4) bottom, the both sides of described fistula joint (5) bottom communicate.
7. the device of collection animal parotid sputum according to claim 1 and 2, is characterized in that: described collecting bag (1) is provided with handle (6).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320875886.5U CN203700242U (en) | 2013-12-26 | 2013-12-26 | Device for collecting animal parotid saliva |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320875886.5U CN203700242U (en) | 2013-12-26 | 2013-12-26 | Device for collecting animal parotid saliva |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203700242U true CN203700242U (en) | 2014-07-09 |
Family
ID=51050708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320875886.5U Expired - Lifetime CN203700242U (en) | 2013-12-26 | 2013-12-26 | Device for collecting animal parotid saliva |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203700242U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104630052A (en) * | 2015-01-22 | 2015-05-20 | 华南农业大学 | Device for collecting animal parotid gland saliva |
| CN107690278A (en) * | 2015-06-08 | 2018-02-13 | 勃林格殷格翰维特梅迪卡有限公司 | Reception device and the method for obtaining saliva sample |
| CN107735665A (en) * | 2015-06-08 | 2018-02-23 | 勃林格殷格翰维特梅迪卡有限公司 | For obtaining the method and collection device of saliva sample |
| RU2799128C1 (en) * | 2023-05-17 | 2023-07-04 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method of obtaining oral fluid in rabbits |
-
2013
- 2013-12-26 CN CN201320875886.5U patent/CN203700242U/en not_active Expired - Lifetime
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104630052A (en) * | 2015-01-22 | 2015-05-20 | 华南农业大学 | Device for collecting animal parotid gland saliva |
| CN107690278A (en) * | 2015-06-08 | 2018-02-13 | 勃林格殷格翰维特梅迪卡有限公司 | Reception device and the method for obtaining saliva sample |
| CN107735665A (en) * | 2015-06-08 | 2018-02-23 | 勃林格殷格翰维特梅迪卡有限公司 | For obtaining the method and collection device of saliva sample |
| US10888305B2 (en) | 2015-06-08 | 2021-01-12 | Boehringer Ingelheim Vetmedica Gmbh | Receiving device and method for obtaining a saliva sample |
| US10959707B2 (en) | 2015-06-08 | 2021-03-30 | Boehringer Ingelheim Vetmedica Gmbh | Method for obtaining a saliva sample and collecting device |
| CN107690278B (en) * | 2015-06-08 | 2021-10-15 | 勃林格殷格翰维特梅迪卡有限公司 | Receiving device and method for obtaining saliva sample |
| RU2799128C1 (en) * | 2023-05-17 | 2023-07-04 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Method of obtaining oral fluid in rabbits |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204798549U (en) | Well minute pipe assembly that contains multi -functional adapter | |
| CN203700242U (en) | Device for collecting animal parotid saliva | |
| CN104546017A (en) | Animal saliva collecting device | |
| CN204394576U (en) | A kind of animal saliva collecting device | |
| CN201855492U (en) | Aortic cannula | |
| CN106798577A (en) | A kind of Ruminant rumen fluid collecting device | |
| CN204319480U (en) | A kind of negative-pressure type stomach tube | |
| CN204709432U (en) | The simple and easy gravity that a kind of flow velocity is adjustable feeds perfusion instrument | |
| CN203590821U (en) | Lamb lactation device capable of feeding medicine during lactation | |
| CN201189299Y (en) | Double-enter T-piece silica gel nasal feeding tube of different size and caliber | |
| CN205379383U (en) | Animal doctor is with animal medicine feed ware | |
| CN218572583U (en) | Negative pressure gastric lavage device for pediatric nursing | |
| CN201370596Y (en) | Device for collecting saliva of submandibular gland | |
| CN201295415Y (en) | New nasus-passing stomach and intestine trachea | |
| CN203609740U (en) | Enema tube with detachable airbag | |
| CN209048187U (en) | It is a kind of for collecting the collection device of piglet testis and tail tissue exudates | |
| CN2910245Y (en) | Multifunction T-shape nasal feeding stomach tube | |
| CN201253353Y (en) | Super-light infant feeding device | |
| CN209611186U (en) | A kind of animal rumens liquid sampler | |
| CN201791220U (en) | Disposable oxygen absorption continuous humidifying device | |
| CN201558325U (en) | Premature infant assisting feeder | |
| CN209347300U (en) | A kind of animal and veterinary continuous medicine-filling device | |
| CN207492997U (en) | A kind of sputum aspirator tube with reinforced wire | |
| CN209332366U (en) | A kind of animal and veterinary drencher | |
| CN201469847U (en) | Oxygen inhalator with improved structure |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230921 Address after: Room 70E, 12th Floor, Minggao Center, 123 Yingbin Avenue, Xinhua Street, Huadu District, Guangzhou City, Guangdong Province, 510800 Patentee after: Guoke Runfeng (Guangzhou) Biopharmaceutical Co.,Ltd. Address before: 510642 No. five, 483 mountain road, Guangzhou, Guangdong, Tianhe District Patentee before: SOUTH CHINA AGRICULTURAL University |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20140709 |