CN203677088U - Compatible fixing device of small animal formation of image - Google Patents
Compatible fixing device of small animal formation of image Download PDFInfo
- Publication number
- CN203677088U CN203677088U CN201420048465.XU CN201420048465U CN203677088U CN 203677088 U CN203677088 U CN 203677088U CN 201420048465 U CN201420048465 U CN 201420048465U CN 203677088 U CN203677088 U CN 203677088U
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- toy
- head
- small animal
- fixing
- groove
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- 241001465754 Metazoa Species 0.000 title claims abstract description 41
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003384 imaging method Methods 0.000 claims abstract description 35
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 9
- 239000001301 oxygen Substances 0.000 claims abstract description 9
- 230000035479 physiological effects, processes and functions Effects 0.000 claims abstract description 9
- 230000029058 respiratory gaseous exchange Effects 0.000 claims abstract description 9
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229920005479 Lucite® Polymers 0.000 claims description 16
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 16
- 238000010276 construction Methods 0.000 claims description 3
- 238000001514 detection method Methods 0.000 abstract description 3
- 239000011521 glass Substances 0.000 abstract 5
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 238000010171 animal model Methods 0.000 description 4
- 206010016807 Fluid retention Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000011503 in vivo imaging Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The compatible fixing device for small animal imaging comprises an organic glass outer bed body and an organic glass small animal fixing plate, wherein the organic glass outer bed body consists of a bottom plate, a side wall and a top cover; a cavity for storing constant-temperature water is arranged in the bottom plate, a water inlet and a water outlet which are communicated with the cavity are respectively arranged at two ends of the bottom plate, a groove which penetrates through the bottom plate is arranged on the upper surface of the bottom plate, the width of the groove is the same as the width nominal size of the small animal fixing plate and is in movable fit with the small animal fixing plate, and an oxygen tube and a heart rate and respiration physiology detection pipeline through hole are arranged on one side wall of the outer bed body opposite to the end part of the groove; the small animal fixing plate is provided with an organic glass head fixer for fixing the head of a small animal, an organic glass fixing column for fixing the limbs of the small animal and a fixing belt for fixing the waist of the small animal; the toy fixed plate is installed in the recess that the bottom plate upper surface set up, and its one end that is provided with the head fixer is provided with the lateral wall of oxygen hose and rhythm of the heart, breathing physiology detection line via hole towards outside bed body.
Description
Technical field
This utility model belongs to medical auxiliary apparatus field, is specifically related to a kind of small animal imaging fixture.
Background technology
Toy in-vivo imaging was widely used in detection of biological function in the last few years, was especially applied to the precise positioning of pathological changes in experimental animals.The extensive use of the imaging devices such as MRI, CT and toy optical imaging experiments has advanced the research of toy disease model greatly.
At present, the fixture kind that small animal imaging is used is few, function singleness, and be difficult to compatible multiple imaging device.Most of small animal imaging fixtures by one dull and stereotyped the and dull and stereotyped upper fixing band arranging or/and fixed leg form.When use, toy is bound to flat board upper, by tooth or ear clip, head is fixed.Current device can not ensure toy in different time rechecking or accept to keep same position when distinct device detects, and can not provide environment clean, constant temperature for toy.And cleannes and the temperature of laboratory animal environment of living in are extremely important when imaging, not only having influence on experiment carries out smoothly, also can affect experimental result, even jeopardizes the life of laboratory animal.
Utility model content
The purpose of this utility model is to overcome the deficiencies in the prior art, provides a kind of small animal imaging compatible fixture, to can use with multiple imaging device is compatible, and can provide environment clean, constant temperature for imaging experiment animal.
The compatible fixture of small animal imaging described in the utility model comprises the lucite outer bed body and the lucite toy fixing head that are made up of base plate, sidewall and top cover; In described base plate, be provided with the cavity of savings thermostatted water, base plate two ends are respectively equipped with the water inlet and the outlet that communicate with described cavity, plate upper surface is provided with the groove that connects base plate, the width nominal dimension of the width of described groove and described toy fixing head is identical and coordinate for moving, is provided with oxygen hose and heart rate, physiology of respiration detects pipeline via hole on outer bed body one sidewall relative with described groove ends; On described toy fixing head, be provided with for the lucite head holder of fixing toy head, for the lucite fixed leg of fixing toy extremity with for fixing the fixing band of toy waist; Toy fixing head is arranged in the groove that plate upper surface arranges, and its one end that is provided with head holder outward bed body is provided with oxygen hose and heart rate, physiology of respiration and detects the sidewall of pipeline via hole.
The compatible fixture of small animal imaging described in the utility model, its head holder has following two types:
1, head holder is the reeded cuboid of tool or arc column, or screw bonding with toy fixing head is connected, and the groove on described cuboid or arc column and toy fixing head surround the toy head lock chamber that experiment is required and size can not be adjusted.
The head holder of this type is divided into again split-type structural and monolithic construction.The head holder of described split-type structural is divided into the first half and Lower Half vertically, and the first half and Lower Half are by lucite gemel connection.The head holder of described monolithic construction is integrated.
The head holder of this type can be prepared into plurality of specifications by the head size of toy according to experiment, in order to selecting.
2, head holder is made up of two reeded arc columns of tool, two reeded arc columns of tool are connected with toy fixing head by screw respectively and clamping mutually, the groove of described arc column and toy fixing head surround toy head lock chamber, the size of this toy head lock chamber is adjusted by the installing space between described two arc columns, can determine the installing space of two arc columns on toy fixing head by the head size of toy according to experiment.
The compatible fixture of small animal imaging described in the utility model, described plate upper surface is provided with the first scale near the edge of groove along the length direction of groove, described toy fixing head upper surface edge is along its length provided with the second scale, the second scale of the first scale of plate upper surface setting and the setting of toy fixing head upper surface matches, to can accurately judge the shift position of toy fixing head.
The compatible fixture of small animal imaging described in the utility model has following beneficial effect:
1, because toy fixing head has the accurate positioner of scale, and toy fixing head can carry out the head of toy, foot, abdominal part comprehensive fixing.Thereby work as toy and accept different equipment inspection, or in the time that the same equipment of different time points detects repeatedly, can ensure that same toy is in identical scanning position and correct position.Meanwhile, comprehensive fixture can greatly reduce it and move or breathe the artifact causing, and improves test accuracy.This device can coordinate different imaging devices to use, and without repeated disassembled and assembled toy, thereby save time, raise the efficiency.Be conducive to the fusion of multi-modal data of later stage.
2, due to the cavity being provided with in base plate for saving thermostatted water, can continue by additional water circulating pump the thermostatted water that passes into physiological temp of circulation, ensure toy thermostasis, improve the accuracy of experimental result.On the other hand, after base plate water-retention, be equivalent to water mould, thereby can increase MRI signal, reach the object that strengthens toy development effect.
3, because outer bed body is body structure, top cover can open and close, and after sterilization, provides independently environment of cleaning for experiment detects toy.Therefore can greatly reduce toy that immunity is low and infect because of pollution, and then cause dead generation, also can avoid laboratory animal manure contamination scanning bed.
Brief description of the drawings
Fig. 1 is a kind of structural representation that the compatible fixture of small animal imaging described in the utility model is opened top cover.
Fig. 2 is a kind of structural representation that the compatible fixture of small animal imaging described in the utility model is closed top cover.
Fig. 3 is the structural representation of base plate in the compatible fixture of small animal imaging described in the utility model.
Fig. 4 is the top view of Fig. 3.
Fig. 5 is the A-A cutaway view of Fig. 4.
Fig. 6 is the structural representation of toy fixing head in the compatible fixture of small animal imaging described in utility model.
Fig. 7 is the fixed form figure of toy on toy fixing head.
Fig. 8 is the structural representation of the first head holder in the compatible fixture of small animal imaging described in the utility model.
Fig. 9 is the left view of Fig. 8.
Figure 10 is the right view of Fig. 8.
Figure 11 is the structural representation of the second head holder in the compatible fixture of small animal imaging described in the utility model.
The left view of Figure 12 Figure 11.
The right view of Figure 13 Figure 11.
Figure 14 is the structural representation of the third head holder in the compatible fixture of small animal imaging described in the utility model.
Figure 15 is the structural representation of the 4th kind of head holder in the compatible fixture of small animal imaging described in the utility model.
In figure, 1-outer bed body, 1-1-base plate, 1-2-sidewall, 1-3-top cover, 1-4-water inlet, 1-5-outlet, 1-6-groove, 1-7-cavity, 1-8-the first scale, 1-9-oxygen hose and heart rate, physiology of respiration detect pipeline via hole; 2-toy fixing head, 2-1-head holder, 2-2-fixed leg, 2-3-fixing band, 2-4-the second scale, 2-1-1-first half, 2-1-2-Lower Half, 2-1-3-hasp, 2-1-4-screw, 2-1-5-the first arc column, 2-1-6-the second arc column, 2-1-7-draw-in groove, 2-1-8-latch.
Detailed description of the invention
Below by embodiment, the compatible fixture of small animal imaging described in the utility model is described further.
Embodiment 1
Described in the present embodiment, the structure of the compatible fixture of small animal imaging as shown in Figures 1 to 7, comprises lucite outer bed body 1 and lucite toy fixing head 2, described toy fixing head 2 is the tabular body of rectangle, toy fixing head is provided with the lucite head holder 2-1 for fixing toy head, for the lucite fixed leg 2-2 of fixing toy extremity with for fixing the fixing band 2-3 of toy waist, toy fixing head 2 upper surfaces edge is along its length provided with the second scale 2-4, for convenience of binding simplified structure, described fixed leg 2-2 is four screws, described fixing band 2-3 is two elastic cords with velcro, impacts to greatly reduce the eupnea to toy, the outer bed of described lucite body 1 is the body structure being made up of base plate 1-1, sidewall 1-2 and top cover 1-3, and base plate 1-1 is the tabular body of rectangle, and sidewall 1-2 is four, and each sidewall is connected with four sides of base plate respectively, and top cover 1-3 and a sidewall are hinged, in described base plate 1-1, be provided with the cavity 1-7 for holding thermostatted water, base plate two ends are respectively equipped with the water inlet 1-4 and the outlet 1-5 that communicate with described cavity 1-7, plate upper surface is provided with the groove 1-6 that connects base plate along floor length direction, edge near groove is provided with the first scale 1-8 along the length direction of groove, the second scale 2-4 of described the first scale 1-8 and the 2 upper surface settings of toy fixing head matches, the width nominal dimension of the width of described groove 1-6 and described toy fixing head 2 is identical and coordinate for moving, on the outer bed body one sidewall 1-2 relative with described groove 1-6 end, be provided with oxygen hose and heart rate, physiology of respiration detects pipeline via hole 1-9, toy fixing head 2 is arranged in the groove 1-6 that base plate 1-1 upper surface arranges, and its one end that is provided with head holder outward bed body is provided with oxygen hose and heart rate, physiology of respiration and detects the sidewall 1-2 of pipeline via hole.
Described head holder 2-1 is as Fig. 8, Fig. 9, Figure 10, for thering is the cuboid of cavity, be divided into vertically first half 2-1-1 and Lower Half 2-1-2, its Lower Half 2-1-2 and toy fixing head 2 are bonding, one side of the first half and Lower Half is by lucite gemel connection, the first half and Lower Half correspondence position are respectively equipped with hasp 2-1-3, and the groove of described cuboid and toy fixing head 2 surround the toy head lock chamber that experiment is required and size can not be adjusted.In the time that needs are put into toy head, the first half is started, after toy head is put into, the first half is closed and pinned, prevent from moving and becoming flexible because of toy.
The compatible fixture of small animal imaging in the present embodiment and the difference of embodiment 1 are the fixed form of head holder 2-1 on toy fixing head 2.As shown in Figure 11～13, the Lower Half 2-1-2 of head holder is fixed on toy fixing head 2 by screw 2-1-4.
The compatible fixture of small animal imaging in the present embodiment and the difference of embodiment 1 are shape, structure and the fixed form on toy fixing head 2 of head holder 2-1.As shown in figure 14, head holder 2-1 is the monoblock type arc column with cavity, is fixed on toy fixing head 2 by screw 2-1-4.
Embodiment 4
The compatible fixture of small animal imaging in the present embodiment and the difference of embodiment 1 are shape, structure and the fixed form on toy fixing head 2 of head holder 2-1.As shown in figure 15, head holder is made up of reeded the first arc column 2-1-5 of tool and the second arc column 2-1-6, the end of the first arc column 2-1-5 is provided with engaging tooth 2-1-8, the extrados of the second arc column 2-1-6 is provided with the slot 2-1-7 matching with engaging tooth, two reeded arc columns of tool are connected with toy fixing head 2 by screw 2-1-4 respectively and clamping mutually, and the groove of described arc column and toy fixing head 2 surround the toy head lock chamber that experiment is required and size is adjustable.The adjustment of toy head lock chamber size realizes by the adjustment of installing space between two arc columns.
Claims (6)
1. the compatible fixture of small animal imaging, is characterized in that comprising the outer bed of the lucite body (1) and the lucite toy fixing head (2) that are made up of base plate (1-1), sidewall (1-2) and top cover (1-3); In described base plate (1-1), be provided with the cavity (1-7) of savings thermostatted water, base plate two ends are respectively equipped with the water inlet (1-4) and the outlet (1-5) that communicate with described cavity (1-7), plate upper surface is provided with the groove (1-6) that connects base plate, the width nominal dimension of the width of described groove (1-6) and described toy fixing head (2) is identical and coordinate for moving, is provided with oxygen hose and heart rate, physiology of respiration detects pipeline via hole (1-9) on outer bed body one sidewall (1-2) relative with described groove ends; On described toy fixing head (2), be provided with for the lucite head holder (2-1) of fixing toy head, for the lucite fixed leg (2-2) of fixing toy extremity with for fixing the fixing band (2-3) of toy waist; Toy fixing head (2) is arranged in the groove (1-6) that base plate (1-1) upper surface arranges, and its one end that has a head holder outward bed body is provided with oxygen hose and heart rate, physiology of respiration and detects the sidewall (1-2) of pipeline via hole.
2. the compatible fixture of small animal imaging according to claim 1, it is characterized in that described head holder (2-1) is the reeded cuboid of tool or arc column, or screw bonding with toy fixing head (2) is connected, and the groove on described cuboid or arc column and toy fixing head (2) surround the toy head lock chamber that experiment is required and size can not be adjusted.
3. the compatible fixture of small animal imaging according to claim 2, is characterized in that described head holder is divided into the first half and Lower Half vertically, and the first half and Lower Half are by lucite gemel connection.
4. the compatible fixture of small animal imaging according to claim 2, is characterized in that described head holder is monolithic construction.
5. the compatible fixture of small animal imaging according to claim 1, it is characterized in that described head holder (2-1) is made up of two reeded arc columns of tool, two reeded arc columns of tool are connected with toy fixing head (2) by screw respectively and clamping mutually, the groove of described arc column and toy fixing head (2) surround toy head lock chamber, and the size of this toy head lock chamber is adjusted by the installing space between described two arc columns.
6. according to the compatible fixture of small animal imaging described in arbitrary claim in claim 1 to 5, it is characterized in that described plate upper surface is provided with the first scale (1-8) near the edge of groove along the length direction of groove, described toy fixing head (2) upper surface edge is along its length provided with the second scale (2-4), and the first scale (1-8) that plate upper surface arranges matches with the second scale (2-4) that toy fixing head (2) upper surface arranges.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420048465.XU CN203677088U (en) | 2014-01-26 | 2014-01-26 | Compatible fixing device of small animal formation of image |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420048465.XU CN203677088U (en) | 2014-01-26 | 2014-01-26 | Compatible fixing device of small animal formation of image |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203677088U true CN203677088U (en) | 2014-07-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420048465.XU Expired - Fee Related CN203677088U (en) | 2014-01-26 | 2014-01-26 | Compatible fixing device of small animal formation of image |
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| CN (1) | CN203677088U (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257439A (en) * | 2014-10-28 | 2015-01-07 | 沈阳医学院 | Enclosed animal experiment operation box |
| CN105213061A (en) * | 2015-08-19 | 2016-01-06 | 中国科学院深圳先进技术研究院 | A kind of medical experiment animal fixing device |
| CN106308839A (en) * | 2016-08-11 | 2017-01-11 | 四川大学华西医院 | CT (computed tomography) compatible breathing training and autonomous adjusting device and using method thereof |
| CN107907845A (en) * | 2017-12-15 | 2018-04-13 | 国家纳米科学中心 | A kind of measuring device for toy NMR imaging |
| CN108362724A (en) * | 2018-04-19 | 2018-08-03 | 国家纳米科学中心 | A kind of sample fixing device, sample scanning means and specimen storage device |
| CN108498951A (en) * | 2018-02-06 | 2018-09-07 | 王文春 | Magnetic field shielding case |
| CN111820873A (en) * | 2020-03-31 | 2020-10-27 | 同济大学 | Living mouse muscle confocal imaging chamber |
| CN112043533A (en) * | 2020-09-10 | 2020-12-08 | 姬世伟 | A animal vital sign short-term test platform for livestock-raising |
-
2014
- 2014-01-26 CN CN201420048465.XU patent/CN203677088U/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257439A (en) * | 2014-10-28 | 2015-01-07 | 沈阳医学院 | Enclosed animal experiment operation box |
| CN105213061A (en) * | 2015-08-19 | 2016-01-06 | 中国科学院深圳先进技术研究院 | A kind of medical experiment animal fixing device |
| CN106308839A (en) * | 2016-08-11 | 2017-01-11 | 四川大学华西医院 | CT (computed tomography) compatible breathing training and autonomous adjusting device and using method thereof |
| CN107907845A (en) * | 2017-12-15 | 2018-04-13 | 国家纳米科学中心 | A kind of measuring device for toy NMR imaging |
| CN108498951A (en) * | 2018-02-06 | 2018-09-07 | 王文春 | Magnetic field shielding case |
| CN108362724A (en) * | 2018-04-19 | 2018-08-03 | 国家纳米科学中心 | A kind of sample fixing device, sample scanning means and specimen storage device |
| CN108362724B (en) * | 2018-04-19 | 2024-04-09 | 国家纳米科学中心 | Sample fixing device, sample scanning device and sample storage device |
| CN111820873A (en) * | 2020-03-31 | 2020-10-27 | 同济大学 | Living mouse muscle confocal imaging chamber |
| CN112043533A (en) * | 2020-09-10 | 2020-12-08 | 姬世伟 | A animal vital sign short-term test platform for livestock-raising |
| CN112043533B (en) * | 2020-09-10 | 2022-04-19 | 重庆市天友乳业股份有限公司 | A animal vital sign short-term test platform for livestock-raising |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140702 Termination date: 20210126 |