CN203616170U - Sampling head capable of realizing rapid sampling - Google Patents
Sampling head capable of realizing rapid sampling Download PDFInfo
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- CN203616170U CN203616170U CN201320674331.4U CN201320674331U CN203616170U CN 203616170 U CN203616170 U CN 203616170U CN 201320674331 U CN201320674331 U CN 201320674331U CN 203616170 U CN203616170 U CN 203616170U
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- internal diameter
- sampling
- kapillary
- reducing body
- ratio
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- 238000005070 sampling Methods 0.000 title claims abstract description 53
- 239000007788 liquid Substances 0.000 claims abstract description 70
- 239000000126 substance Substances 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 15
- 239000012530 fluid Substances 0.000 description 11
- 230000000694 effects Effects 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 239000011521 glass Substances 0.000 description 3
- 210000005239 tubule Anatomy 0.000 description 3
- 230000001133 acceleration Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000004134 energy conservation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The utility model relates to a sampling head, particularly to a sampling head capable of realizing rapid sampling. The sampling head comprises a capillary tube consisting of an equal-inner-diameter tube body and a reducing-inner-diameter tube body which are communicated with each other; a liquid inlet is formed in one end of the equal-inner-diameter tube body, and a liquid outlet is formed in one end of the reducing-inner-diameter tube body; and the ratio of the inner diameter of the liquid outlet to the inner diameter of the liquid inlet is (0.3-0.8):1. The sampling head is applicable to quantitative sampling in biological, chemical and medical fields and has the advantages of convenience in use and capability of increasing the sampling rate significantly.
Description
Technical field
The utility model relates to a kind of sampling head, particularly relates to a kind of sampling head of fast sampling, and it is applicable to the quantitative sampling of biology, chemistry, medical domain.
Background technology
Kapillary has a wide range of applications in the sampling process of turbidimetric test, and it is generally used for trace or the sampling of sample in a small amount.Existing kapillary is generally glass capillary, and its cost is higher, and the waste causing after use abandons is larger.Developed the kapillary of Integral injection molding, it can reduce costs greatly compared with glass capillary, but identical with glass capillary, and it is the tubular structure of the small and homogeneous of internal diameter.The internal diameter of the two is generally 0.2 ~ 2mm, has guaranteed automatically to suck liquid by syphonic effect capillaceous.
From Bernoulli (Bernoulli) law, i.e. formula (1).
The pressure that in formula, p is fluid;
ρ is the density of fluid;
V is fluid velocity;
H is plumb height;
G is acceleration of gravity;
C is constant.
Pressure energy p, gravitional force ρ gh and kinetic energy (1/2) the * ρ v of the every representation unit volume respectively of above formula fluid
2, along in stream line motion process, summation remains unchanged, i.e. gross energy conservation.The medium velocity that flows increases, and pressure just reduces; Speed reduces, and pressure just increases.So along with the increase of liquid lifting height in kapillary, gravitional force increases, speed can reduce thereupon, and pressure further increases.Liquid can speed slow down slowly in the time rising to 80% left and right of kapillary overall height, and the large appointment of height rise time of remaining 20% left and right is the more than 10 times of early stage.
Therefore, existing kapillary is grown and even cannot be sucked liquid to top sample time, thereby does not reach quantitative object.But in some tests, especially needing the sample gathering is blood sample, if sample time is longer, needs again to puncture to get blood after wound blood coagulation, can cause certain body burden to experimenter.Therefore, need to develop a kind of kapillary that can improve sample rate.
Utility model content
It is a kind of easy to use that the purpose of this utility model is to provide, and can realize the sampling head of fast sampling.
In order to achieve the above object, the utility model is by the following technical solutions:
Sampling head of the present utility model comprises kapillary, described kapillary is made up of internal diameter reducing body, one end of described internal diameter reducing body is provided with liquid inlet, the other end of described internal diameter reducing body is provided with liquid outlet, and the ratio of described liquid outlet internal diameter capillaceous and liquid inlet internal diameter is 0.3 ~ 0.8:1;
Or described kapillary is made up of the isometrical body of the internal diameter being connected and internal diameter reducing body, and one end of the isometrical body of described internal diameter is provided with liquid inlet, and one end of described internal diameter reducing body is provided with liquid outlet,
The ratio of described liquid outlet internal diameter capillaceous and liquid inlet internal diameter is 0.3 ~ 0.8:1.
Further, the length ratio of the isometrical body of internal diameter described in the utility model and internal diameter reducing body is 0~90:1.
Further, when kapillary described in the utility model is made up of the isometrical body of the internal diameter being connected and internal diameter reducing body, the length ratio of the isometrical body of described internal diameter and internal diameter reducing body is 5 ~ 20:1.
Further, when kapillary described in the utility model is made up of the isometrical body of the internal diameter being connected and internal diameter reducing body, the ratio of the length of described liquid inlet internal diameter and described internal diameter reducing body is 0.5 ~ 2.0:1.
Further, when kapillary described in the utility model is made up of the isometrical body of the internal diameter being connected and internal diameter reducing body, the ratio of the length of described liquid inlet internal diameter and described internal diameter reducing body is 0.7 ~ 1.0:1.
Further, length capillaceous described in the utility model is 5~15mm.
Further, the utility model also comprises the support for fixed capillary; On described support, be fixed with 1 ~ 2 kapillary.
Further, the utility model also comprises the fixed leg that is fixed on back-end support.
Kapillary of the present utility model refers to that internal diameter is little, can make liquid therein side overcome terrestrial attraction and the tubule that rises or decline, be generally the tubule of internal diameter 0.2 ~ 2mm.Kapillary of the present utility model can be that quantitative capillary tube can be also common kapillary.
The isometrical body of internal diameter described in the utility model and internal diameter reducing body ratio are 0~90:1, in the time that the ratio of the isometrical body of internal diameter and internal diameter reducing body is 0:1, and for there is no the isometrical body of internal diameter, the evenly kapillary of reducing.But the isometrical body of internal diameter is set can in the time reaching same sampling rate, shortens the length of sampling head.
On support described in the utility model, be fixed with 1 ~ 2 kapillary, fixed form can be those skilled in the art adopt conventional fixed form, as peg graft etc., can be also the mode of integrated injection forming.
The fixed leg that is fixed on back-end support described in the utility model, the fixed form of fixed leg and support can be those skilled in the art adopt conventional fixed form, as peg graft etc., can be also the mode of integrated injection forming.
The good effect that the utility model adopts technique scheme to obtain is:
The internal diameter of quantitative capillary tube of the present utility model adopts and becomes size design, and outlet internal diameter is less than entrance internal diameter, and accelerate liquid sample and entered speed capillaceous, according to Bernoulli equation, formula (2); In pipeline, have the fluid of a steady flow, the height difference of the fluid column in the vertical opening tubule at pipeline different cross section place, shows in the liquid of steady flow, the local pressure that flow velocity is large is little, and the local pressure that flow velocity is little is large.
P+(pv
2/ 2)=constant formula (2)
The pressure that in formula, p is fluid
ρ is the density of fluid;
V is fluid velocity;
Relevant with the height (H) of internal diameter capillaceous (d) and suction liquid according to the flow velocity of the known capillary liquid in pipe of absorption motive power formula (3), in height one timing capillaceous, dwindle the flow velocity that internal diameter capillaceous can improve fluid, further reduce the pressure of fluid.
V=√ [(2gH)/(1+ ζ+λ L/d)] formula (3)
In formula, √ is radical sign;
V is U trap mean velocity in section;
G is acceleration of gravity;
H is acting head capillaceous, i.e. the discrepancy in elevation of the kapillary entrance point water surface and the endpiece water surface;
ζ is coefficient of shock resistance capillaceous;
λ is on-way resistance coefficient capillaceous;
D is internal diameter capillaceous.
The ratio of liquid outlet internal diameter of the present utility model and liquid inlet internal diameter is 0.3 ~ 0.8:1, dwindles liquid outlet internal diameter, can improve the mobile speed of inner air, reduces internal pressure, thereby effectively improves in the end 20% ascending velocity of liquid in sampling head; Because dwindled sampling head internal diameter, effectively improved again siphon flow velocity simultaneously.
Internal diameter of the present utility model is made up of the isometrical body of internal diameter and the linking of internal diameter reducing body of intercommunication; The length ratio of the isometrical body of described internal diameter and internal diameter reducing body is 0~90:1; When sample rate one timing, the isometrical body of internal diameter is set and can dwindles length capillaceous.
Structure of the present utility model is specially adapted to the kapillary that length is 5 ~ 15mm.
Support of the present utility model grips kapillary can be easy to use time.
Fixed leg of the present utility model is for using on the quantitative filling device of when needed the utility model being pegged graft.
Accompanying drawing explanation
Fig. 1 is the structural representation of the utility model embodiment 1;
Fig. 2 is the structural representation of the utility model embodiment 2;
Fig. 3 is the cross-sectional schematic of the utility model embodiment 2;
Fig. 4 is the structural representation of the utility model embodiment 3;
In the accompanying drawings, 1 kapillary, 1-1 liquid outlet, 1-2 liquid inlet, the isometrical body of 1-3 internal diameter, 1-4 internal diameter reducing body, 2 supports, 3 fixed legs.
Embodiment
What the xsect of quantitative capillary tube 1 internal diameter of the present utility model was general is circular, and as known to those skilled in the art, the shape of quantitative capillary tube internal diameter xsect can not affect the effect of its use.
Can select, the utility model can use separately, also can be used in conjunction with quantitative filling device, quantitative filling device wherein includes but not limited to commercially available quantitative filling device or the disclosed charging point part of patent CN202204706U (not containing part capillaceous).
Support of the present utility model grips kapillary can be easy to use time.Fixed leg of the present utility model is for using on the quantitative filling device of when needed the utility model being pegged graft.
The utility model can be further pegged graft on quantitative filling device and is used by fixed leg 3, for the selection of fixed leg quantity, 1 or multiple function that all can not affect its grafting itself, and according to the needs of concrete grafting technique, selecting shape and the quantity of fixed leg is that those skilled in the art can judge and select according to common practise.
To the above-mentioned explanation of the disclosed embodiments, make professional and technical personnel in the field can realize or use the utility model.To be apparent for those skilled in the art to the multiple modification of these embodiment, General Principle as defined herein can, in the situation that not departing from spirit or scope of the present utility model, realize in other embodiments.Therefore, the utility model will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
As shown in Figure 1, the kapillary 1 described in the present embodiment is connected and is formed by the isometrical body 1-3 of the internal diameter being connected and internal diameter reducing body 1-4; One end of the isometrical body 1-3 of described internal diameter is provided with liquid inlet 1-2, and one end of described internal diameter reducing body 1-4 is provided with liquid outlet 1-1; Described liquid outlet 1-1 internal diameter (D1) is 0.5:1 with the ratio of liquid inlet 1-2 internal diameter (D2); The length (L2) of the isometrical body 1-3 of described internal diameter is 20:1 with the ratio of the length (L1) of internal diameter reducing body 1-4; Described liquid inlet (1-2) internal diameter (D2) is 1:1 with the ratio of the length (L1) of described internal diameter reducing body; Capillary pipe length is 10mm.
This technique effect capillaceous is: can increase substantially sample rate, and relevant to the mobility of institute collected specimens, can improve 5 ~ 20 times of sampling rates.
As shown in Figures 2 and 3, the present embodiment comprises support 2, is fixed on the kapillary 1 of support front end and is fixed on the fixed leg 3 of support 2 rear ends.
Described kapillary 1 is connected and is formed by the isometrical body 1-3 of the internal diameter being connected and internal diameter reducing body 1-4; One end of the isometrical body 1-3 of described internal diameter is provided with liquid inlet 1-2, and the other end of described internal diameter reducing body 1-4 is provided with liquid outlet 1-1; Described liquid outlet 1-1 internal diameter (D1) is 0.3:1 with the ratio of liquid inlet 1-2 internal diameter (D2); The length (L2) of the isometrical body 1-3 of described internal diameter is 30:1 with the ratio of the length (L1) of internal diameter reducing body 1-4; Described liquid inlet (1-2) internal diameter (D2) is 1.2:1 with the ratio of the length (L1) of described internal diameter reducing body; Capillary pipe length is 15mm.
This technique effect capillaceous is: can increase substantially sample rate, and relevant to the mobility of institute collected specimens, can improve 5 ~ 20 times of sampling rates.
As shown in Figure 4, kapillary 1 described in the present embodiment is made up of internal diameter reducing body 1-4, one end of described internal diameter reducing body 1-4 is provided with liquid inlet 1-2, the other end of described internal diameter reducing body 1-4 is provided with liquid outlet 1-1, and the ratio of the liquid outlet 1-1 internal diameter of described kapillary 1 and liquid inlet 1-2 internal diameter is 0.7:1; Described liquid inlet 1-2 internal diameter (D2) is 0.5:1 with the ratio of the length (L1) of described internal diameter reducing body; Capillary pipe length is 5mm.
This technique effect capillaceous is: can increase substantially sample rate, and relevant to the mobility of institute collected specimens, can improve 5 ~ 20 times of sampling rates.
Embodiment 4 ~ 9
Embodiment 4 ~ 9 is only internal diameter capillaceous and shape with the difference of embodiment 1 and 2, and its parameter is as shown in table 1.
Comparative example 1 ~ 4
Comparative example 1 ~ 4 is only internal diameter capillaceous and shape with the difference of embodiment 1 and 2, and if comparative example 1 is the kapillary of internal diameter homogeneous, the outlet internal diameter capillaceous of comparative example 2 is only 0.2 kapillary of entrance internal diameter, and the parameter of each comparative example is as shown in table 1.
Each embodiment and comparative example more as shown in table 1.And the time length ratio that gathers water by the sampling head of each embodiment and comparative example is compared with its sampling rate.
The experimental data of table 1 embodiment 1 ~ 9 and comparative example
From the test figure of table 1, under identical sampling medium (water), by changing inner caliber structure capillaceous, can change the time of sampling.As described in Example 2, in the time that liquid outlet internal diameter (D1) is 0.3:1 with the ratio of liquid inlet internal diameter (D2), although its capillary pipe length is 1.5 times of comparative example 1 capillary pipe length, still obviously shorten sample time, illustrate that sample rate enlarges markedly.As described in Example 4, in the time that liquid outlet internal diameter (D1) is 0.8:1 with the ratio of liquid inlet internal diameter (D2), although capillary pipe length is slightly shorter than the capillary pipe length of comparative example 1, be only 1/4 of comparative example 1 sample time, and sampling rate enlarges markedly.As shown in other embodiment, in the time that liquid outlet internal diameter (D1) is 0.3 ~ 0.8:1 with the ratio of liquid inlet internal diameter (D2), all there is the effect of the sampling rate of enlarging markedly.Especially embodiment 6 and embodiment 7, in the time that the ratio of liquid outlet internal diameter (D1) and liquid inlet internal diameter (D2) is 0.5 ~ 0.6:1, although capillary pipe length is approximately 1.5 times of comparative example 1 capillary pipe length, sample time highly significant minimizing.
And, the ratio of the length (L2) of the isometrical body of internal diameter and the length (L1) of internal diameter reducing body, and the ratio of the length (L1) of liquid inlet 1-2 internal diameter (D2) and internal diameter reducing body, there is synergy with aforesaid liquid outlet internal diameter (D1) and the ratio of liquid inlet internal diameter (D2), show using of embodiment 6 and embodiment 9, the liquid outlet internal diameter (D1) of the two is 0.6:1 with the ratio of liquid inlet internal diameter (D2), and the synergy of embodiment 6 is more obvious than embodiment 9; Data as shown in table 1, in the time that the ratio of the length (L2) of the isometrical body of internal diameter and the length (L1) of internal diameter reducing body is 5 ~ 20:1, when liquid inlet 1-2 internal diameter (D2) is 0.7 ~ 1.0:1 with the ratio of the length (L1) of internal diameter reducing body, its synergy is more obvious.This conclusion can further be confirmed by comparative example 2 and comparative example 4.
Moreover liquid outlet internal diameter (D1) is the principal element that affects kapillary sample rate with the ratio of liquid inlet internal diameter (D2), as shown in comparative example 3, although its dependent variable, the value that is L2/L1 and D2/L1 meets the requirements, but the value of D1/D2 is 0.9, now less on the impact of kapillary sample rate, can not reach the remarkable result that the utility model is expected.
Claims (10)
1. a sampling head for fast sampling, is characterized in that it comprises kapillary (1),
Described kapillary (1) is made up of internal diameter reducing body (1-4), one end of described internal diameter reducing body (1-4) is provided with liquid inlet (1-2), the other end of described internal diameter reducing body (1-4) is provided with liquid outlet (1-1), and the ratio of liquid outlet (1-1) internal diameter of described kapillary (1) and liquid inlet (1-2) internal diameter is 0.3 ~ 0.8:1;
Or described kapillary (1) is made up of the isometrical body of the internal diameter being connected (1-3) and internal diameter reducing body (1-4), one end of the isometrical body of described internal diameter (1-3) is provided with liquid inlet (1-2), one end of described internal diameter reducing body (1-4) is provided with liquid outlet (1-1), and the ratio of liquid outlet (1-1) internal diameter of described kapillary (1) and liquid inlet (1-2) internal diameter is 0.3 ~ 0.8:1.
2. the sampling head of fast sampling according to claim 1, is characterized in that the isometrical body of described internal diameter (1-3) and the length ratio of internal diameter reducing body (1-4) are 0~90:1.
3. the sampling head of fast sampling according to claim 2, it is characterized in that in the time that described kapillary (1) is made up of the isometrical body of the internal diameter being connected (1-3) and internal diameter reducing body (1-4), the isometrical body of described internal diameter (1-3) is 5 ~ 20:1 with the length ratio of internal diameter reducing body (1-4).
4. according to the sampling head of the fast sampling described in any one in claim 1 ~ 3, it is characterized in that the ratio of the length of described liquid inlet (1-2) internal diameter and described internal diameter reducing body (1-4) is 0.5 ~ 2.0:1 in the time that described kapillary (1) is made up of the isometrical body of the internal diameter being connected (1-3) and internal diameter reducing body (1-4).
5. according to the sampling head of the described fast sampling of claim 4, it is characterized in that the ratio of the length of described liquid inlet (1-2) internal diameter and described internal diameter reducing body (1-4) is 0.7 ~ 1.0:1 in the time that described kapillary (1) is made up of the isometrical body of the internal diameter being connected (1-3) and internal diameter reducing body (1-4).
6. according to the sampling head of the fast sampling described in any one of claim 1 ~ 3, the length that it is characterized in that described kapillary (1) is 5~15mm.
7. the sampling head of fast sampling according to claim 4, the length that it is characterized in that described kapillary (1) is 5~15mm.
8. the sampling head of fast sampling according to claim 5, the length that it is characterized in that described kapillary (1) is 5~15mm.
9. according to the sampling head of the fast sampling described in any one of claim 1 ~ 3, it is characterized in that it also comprises the support (2) for fixed capillary (1); On described support (2), be fixed with 1 ~ 2 kapillary (1).
10. the sampling head of fast sampling according to claim 9, is characterized in that it also comprises the fixed leg (3) that is fixed on support (2) rear end.
Priority Applications (1)
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CN201320674331.4U CN203616170U (en) | 2013-10-30 | 2013-10-30 | Sampling head capable of realizing rapid sampling |
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CN201320674331.4U CN203616170U (en) | 2013-10-30 | 2013-10-30 | Sampling head capable of realizing rapid sampling |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103558061A (en) * | 2013-10-30 | 2014-02-05 | 石家庄禾柏生物技术股份有限公司 | Sampling head capable of sampling rapidly |
US20150260745A1 (en) * | 2014-03-12 | 2015-09-17 | Dna Medicine Institute, Inc. | Sample consumable and loader |
-
2013
- 2013-10-30 CN CN201320674331.4U patent/CN203616170U/en not_active Expired - Lifetime
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103558061A (en) * | 2013-10-30 | 2014-02-05 | 石家庄禾柏生物技术股份有限公司 | Sampling head capable of sampling rapidly |
CN103558061B (en) * | 2013-10-30 | 2016-09-28 | 石家庄禾柏生物技术股份有限公司 | A kind of sampling head of fast sampling |
US20150260745A1 (en) * | 2014-03-12 | 2015-09-17 | Dna Medicine Institute, Inc. | Sample consumable and loader |
US10180442B2 (en) * | 2014-03-12 | 2019-01-15 | Dna Medicine Institute, Inc. | Sample consumable and loader |
US11268972B2 (en) | 2014-03-12 | 2022-03-08 | Dna Medicine Institute, Inc. | Sample consumable and loader |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
AV01 | Patent right actively abandoned |
Granted publication date: 20140528 Effective date of abandoning: 20160928 |
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C25 | Abandonment of patent right or utility model to avoid double patenting |