CN203609541U - Small animal whole-body tissue corrosion-prevention pouring system - Google Patents
Small animal whole-body tissue corrosion-prevention pouring system Download PDFInfo
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- CN203609541U CN203609541U CN201320749832.4U CN201320749832U CN203609541U CN 203609541 U CN203609541 U CN 203609541U CN 201320749832 U CN201320749832 U CN 201320749832U CN 203609541 U CN203609541 U CN 203609541U
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Abstract
The utility model discloses a small animal whole-body tissue corrosion-prevention pouring system which comprises a pouring platform, a pouring support and a pouring fixing end. An operation platform is arranged on the pouring platform and a corrosion-prevention solution storing device is arranged on the pouring support. A pouring needle, a negative pressure sucking end and a rubber hose attracting end are arranged outside the pouring fixing end. The pouring needle and the corrosion-prevention solution storing device are connected through a medicine pouring pipe provided with a flow valve. A hydraulic system is further installed on the pouring needle. A negative pressure system A is installed on the negative pressure sucking end. A negative pressure system B is installed on the rubber hose attraction end. By means of the small animal whole-body tissue corrosion-prevention pouring system, under single-person operation, pouring the whole body of an experiment animal through the heart can be rapidly achieved, and the pouring pressure can be accurately mastered. The phenomenon that as pressure of manual pouring is hard to control, the pressure is excessively low or large or pouring is insufficient and consequentially, angiorrhexis occurs and a tissue structure is damaged is avoided.
Description
Technical field
This utility model belongs to the biological aseptic technic field of dissecting, and is specifically related to the anticorrosion filling system of a kind of toy body tissue.
Background technology:
At present, in zoopery scientific research process, after laboratory animal need to being put to death, quick filling impregnating fluid, so that fixing organization fast, especially be difficult for dissecting the position of exposure, small, the easy self-dissolving metamorphosis of tissue local, as each internal organs position of experimental animal, eye, internal ear, brain, spinal cord, hypophysis etc.Laboratory animal perfusion in the past, use has the formalin that corrosivity is stronger, paraformaldehyde, ethanol, methanol etc., all human body is had to certain toxicity, and need to put to death after animal, cut fast breast chamber open, fully appear heart, manually fix by sharp tweezer clamping apex, and under assistant helps, the syringe needle of the syringe that contains fixative or infusion bottle pipeline is inserted to animal left ventricle, manual pressure or gravity exert pressure promote perfusion impregnating fluid carry out Perfused vessel, exist apex clamping unstable, easily clip broken heart wall, needle pierces heart is crossed dark and even is penetrated, infusion liquid is spilt and cause perfusion failure, and reduce injection pressure and perfusion effect because of leakage.Simultaneously operated by two people, working place is narrow and small, be difficult to carry out accurate operation in narrow and small animal thoracic cavity, and syringe needle easily thrusts deeply, and injection pressure is difficult to control, and then reduces work efficiency and quality.In operation, for convenient manual operation, can too much cut tissue open, destroy vascular system seal, total body perfusion coverage rate is reduced, consuming time when waste infusion liquid, consumption power, pouring quality seriously reduce, especially puncture heart rear wall and cause perfusion failure, waste experimental model animal, incurs loss through delay follow-up organized processing opportunity, affects scientific research system error and research
Summary of the invention
The purpose of this utility model is to provide the one can one man operation, and simple to operate and be easy to control the anticorrosion filling system of toy body tissue, and this system can improve perfusion precision, perfusion success rate and charging efficiency.
The anticorrosion filling system of toy body tissue that this utility model provides, comprise perfusion platform, perfusion syringe needle, perfusion support, perfusion fixing head, operating board, guidance panel, listerine bin, negative pressure system A and negative pressure system B, described perfusion support is positioned at one end of perfusion platform, which is provided with listerine bin, described perfusion platform is provided with operating board, its right side is provided with guidance panel, described perfusion fixing head is connected with perfusion support by Universal pipe, perfusion fixing head is provided with catheter needle head outward, negative pressure holding head and rubber hose sucking head, between perfusion syringe needle and listerine bin, be connected by the dabbling drug pipe with flow valve, and hydraulic system is also installed on perfusion syringe needle, the piston button of this hydraulic system is positioned on guidance panel, on described negative pressure holding head, negative pressure system A is installed, negative pressure regulating valve and the switch A of this negative pressure system A are all positioned on guidance panel, on described rubber hose sucking head, negative pressure system B is installed, the switch B of this negative pressure system B is positioned on guidance panel.
Above-mentioned hydraulic system comprises hydraulic pressure active piston, the passive piston of hydraulic pressure, hydraulic line and piston button, described hydraulic pressure active piston is connected by hydraulic line with the passive piston of hydraulic pressure, the external perfusion syringe needle of the passive piston of hydraulic pressure, piston button is connected with hydraulic pressure active piston.
Above-mentioned negative pressure system A comprises vacuum suction pump A, negative pressure sticking pipeline, negative pressure regulating valve and switch A, and switch A is all connected with vacuum suction pump A with negative pressure regulating valve, and vacuum suction pump A is connected with negative pressure holding head by negative pressure sticking pipeline.
Above-mentioned negative pressure system B comprises vacuum suction pump B, negative pressure drainage pipeline, drainage bottle and switch B, and switch B is connected with vacuum suction pump B,, negative pressure drainage vessel is connected with rubber hose sucking head by negative pressure drainage pipeline.
Distance between above-mentioned perfusion syringe needle and negative pressure holding head is 0.1-0.5 centimetre (adjustable), on described perfusion syringe needle, be covered with one deck scale layer, described negative pressure holding head is that end is bell-mouthed suction disk-like structure, and is made up of entire glass or macromolecular material.
One side of above-mentioned perfusion support is provided with the lifting platform that can control height, and listerine bin is placed on lifting platform.
The drainage trough that is provided with " returning " font between aforesaid operations platform and perfusion platform, the exit of this drainage trough is provided with liquid waste collector.
Aforesaid operations panel is provided with on and off switch, power supply indicator, negative pressure pump relay indicating light A, switch A, negative pressure regulating valve, negative pressure pump relay indicating light B, switch B and piston button.
The utlity model has following advantage:
(1) in the situation that of one man operation, can realize fast laboratory animal through heart body tissue perfusion, can accurately grasp injection pressure and needle point thrusts the degree of depth;
(2) adopt the fixing heart of absorption, portion of tissue that the blood vessel injury that can avoid manual operation over-exposure tissue to cause causes is lost perfusion situation, and the hypotony of avoiding manual injection pressure to be difficult to control causing, pours into organizational structure insufficient or that the excessive angiorrhexis causing of pressure causes and destroy;
(3) not only can precise fine-adjustment puncture heart, avoid the failure of needle pierces heart perfusion, the waste liquid that can synchronously aspirate after perfusion again enters returnable, reduce the pollution of volatility, toxic antiseptic and other harmful dabbling drugs and the injury to human body, and keep paying close attention to the clean and tidy of specimen and table top;
(4) can, in the situation that regulating holding head with perfusion syringe needle spacing and changing different model perfusion syringe needle, under anatomic microscope, in vitro single organ be implemented to perfusion, and can accurately control perfusion precision and process.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
Fig. 2 is this utility model I place partial schematic diagram;
Fig. 3 is the top view of this utility model perfusion platform;
Fig. 4 is this utility model operating board structure schematic diagram.
In figure: the passive piston 20-hydraulic line of 1-perfusion platform 2-perfusion support, 3-perfusion fixing head, 4-Universal pipe, 5-operating board, 6-guidance panel, 7-listerine bin 8-perfusion syringe needle 9-negative pressure holding head 10-rubber hose sucking head 11-dabbling drug pipe 12-flow valve, 13-on and off switch, 14-lifting platform, 15-drainage trough, 16-liquid waste collector, 17-power supply indicator, 18-hydraulic pressure active piston 19-hydraulic pressure 21-piston button 22-vacuum suction pump A; 23-negative pressure sticking pipeline, 24-negative pressure regulating valve, 25-switch A, 26-vacuum suction pump B, 27-negative pressure drainage pipeline, 28-switch B, 29-negative pressure drainage vessel, 30-negative pressure pump relay indicating light A31-negative pressure relay indicating light B
The specific embodiment
Below in conjunction with drawings and Examples, this utility model is described in further detail.
Embodiment
As shown in Figure 1, Figure 2, Figure 3 and Figure 4, this utility model comprises perfusion platform 1, perfusion support 2 and perfusion fixing head 3, described perfusion support 2 is positioned at one end of perfusion platform 1, described perfusion fixing head 3 is connected with perfusion support 2 by Universal pipe 4, described perfusion platform 1 is provided with operating board 5, and the drainage trough 15 that is provided with " returning " font between perfusion platform 1 and operating board 5, the exit of this drainage trough 15 is provided with liquid waste collector 16, and a side of perfusion platform 1 is also provided with guidance panel 6.One side of described perfusion support 2 is provided with the lifting platform 14 that can control height, and on lifting platform 14, be placed with listerine bin 7, the outer catheter needle head 8 that is provided with of described perfusion fixing head 3, negative pressure holding head 9 and rubber hose sucking head 10, distance between perfusion syringe needle 8 and negative pressure holding head 9 is 0.1-0.5 centimetre (adjustable), on perfusion syringe needle 8, be covered with one deck scale layer, between perfusion syringe needle 8 and listerine bin 7, be connected by the dabbling drug pipe 11 with flow valve 12, and on perfusion syringe needle 8, hydraulic system is also installed, described hydraulic system comprises hydraulic pressure active piston 18, the passive piston 19 of hydraulic pressure, hydraulic line 20 and piston button 21, hydraulic pressure active piston 18 is connected by hydraulic line 20 with the passive piston 19 of hydraulic pressure, the external perfusion syringe needle 8 of the passive piston 19 of hydraulic pressure, hydraulic pressure active piston 18 is connected with piston button 21, and piston button 21 is positioned on guidance panel 6.Described negative pressure holding head 9 is bell-mouthed suction disk-like structure for end, and make (big or small interchangeable) by entire glass or macromolecular material, negative pressure system A is installed on negative pressure holding head 9, this negative pressure system A comprises vacuum suction pump A22, negative pressure sticking pipeline 23, negative pressure regulating valve 24 and switch A25, vacuum suction pump A22 is connected with negative pressure holding head 9 by negative pressure sticking pipeline 23, on vacuum suction pump A22, be also provided with negative pressure regulating valve 24 and switch A25, described negative pressure regulating valve 24 and switch A25 are all positioned on guidance panel 6.On described rubber hose sucking head 10, negative pressure system B is installed, described negative pressure system B comprises vacuum suction pump B26, negative pressure drainage pipeline 27, negative pressure drainage vessel 29 and switch B28, vacuum suction pump B26 is connecting negative pressure drainage vessel 29, negative pressure drainage vessel 29 is connected with rubber hose sucking head 10 by negative pressure drainage pipeline 27, described vacuum suction pump B26 is provided with switch B28, this switch B28 is positioned on guidance panel 6, on described guidance panel 6, be also provided with on and off switch 13, power supply indicator 17, negative pressure pump relay indicating light A30 and negative pressure pump relay indicating light B31 also connect extraneous power supply.
The negative pressure system A that negative pressure holding head 9 is installed, be vacuum suction pump A22 to be set be connected with negative pressure holding head 9 by negative pressure sticking pipeline 23, by the opening and closing of vacuum suction pump A22, and by the control of negative pressure regulating valve 24, realize the size of negative pressure, produce different confinement capabilities, to adapt to the sticking operation of different-thickness, big or small animal hearts.Described negative pressure holding head 9 is bell-mouthed suction disk-like structure for end, and is made up of entire glass or macromolecular material, and the spare parts of being furnished with different-diameter selects, heart adsorption operations or the micrurgy of replaceable adaptation different animals.
The hydraulic system that perfusion syringe needle 8 is installed, be to control hydraulic pressure active piston 18 by the piston button 21 on guidance panel 6, through hydraulic line 20, power is reached to the passive piston 19 of hydraulic pressure, the passive piston 19 of hydraulic pressure is pushed, and then promotion perfusion syringe needle 8 thrusts left ventricle.The puncture of perfusion syringe needle 8 realizes by hydraulic pressure transfer pipeline, can avoid operating position narrow and small, the manually spatial limitation of straightforward manipulation, and the adjusting piercing process that can become more meticulous.Pour into again syringe needle 8 and be provided with scale layer, can determine paracentesis depth.
Realize automatic holding by negative pressure holding head 9 and negative pressure system A with irrigation syringe needle 8 and hydraulic system and fixed and inserting needle puncture apex, guaranteed that puncture needle enters left ventricle, and maintain the work of certain depth.Distance between perfusion syringe needle 8 and negative pressure holding head 9 is 0.1-0.5 centimetre, and adjustable is to adapt to the animal hearts of different sizes.
The negative pressure system B that rubber hose sucking head 10 is installed, be to connect negative pressure drainage vessel 29 by vacuum suction pump B26, negative pressure drainage vessel 29 is connected with rubber hose sucking head 10 by negative pressure drainage pipeline 27 again, realize the infusion liquid that flow out suction blood and right auricle in filling process, and reclaim and enter negative pressure drainage vessel 29.
Between perfusion platform 1 and operating board 5, be provided with " returning " font drainage trough 15, undertaken arranging in liquid waste collector 16 after drain by leak blood and the perfusion waste liquid inhaled in perfusion, to guarantee the clean environmental protection of operating environment.
Use procedure of the present utility model is: turn on the power switch 13, the switch A25 of vacuum suction pump A22, according to the size of laboratory animal, regulate the negative pressure regulating valve 24 of vacuum suction pump A22 stand-by to suitable negative-pressure sucking, and pre-prepd infusion liquid is added to listerine bin 7, adjust flux valve 12 is to minimum, after laboratory animal is put to death, cut off fast breast bone, appear heart, break right auricle, and fixing animal is on operating board 5, the singlehanded perfusion fixing head 3 of taking, negative pressure holding head 9 is approached to laboratory animal apex, can be adsorbed fixing, in addition on the other hand, the piston button 21 of pressing operation panel 6, perfusion syringe needle 8 will thrust animal left ventricle, adjust Universal pipe 4 to appropriate location.Open flow valve 12, start perfusion, visible infusion liquid flows into from left ventricle, after circulation, flows out from animal right auricle, now can be by the vacuum suction of vacuum suction pump b26, make rubber hose sucking head 10 aspirate blood and the infusion liquid of overflowing and enter in negative pressure drainage vessel 29.Observe animal body surface color and infusion liquid color, determine perfusion degree, treat pour into, then close the switch A25 of vacuum suction pump A22, can realize separating of heart and negative pressure holding head 9, enter next animal and pour into or subsequent treatment.Pour into during this time waste liquid as spill and leakage will flow into perfusion operating board drainage trough 15, guiding liquid waste collector 16, recycled.
Claims (7)
1. the anticorrosion filling system of toy body tissue, comprise perfusion platform (1) and perfusion syringe needle (8), it is characterized in that: also comprise perfusion support (2), perfusion fixing head (3), operating board (5), guidance panel (6), listerine bin (7), negative pressure system A and negative pressure system B, described perfusion support (2) is positioned at one end of perfusion platform (1), which is provided with listerine bin (7), described perfusion platform (1) is provided with operating board (5), its right side is provided with guidance panel (6), described perfusion fixing head (3) is connected with perfusion support (2) by Universal pipe (4), the outer catheter needle head (8) that is provided with of perfusion fixing head (3), negative pressure holding head (9) and rubber hose sucking head (10), between perfusion syringe needle (8) and listerine bin (7), be connected by the dabbling drug pipe (11) with flow valve (12), and on perfusion syringe needle (8), hydraulic system is also installed, the piston button (21) of this hydraulic system is positioned on guidance panel (6), on described negative pressure holding head (9), negative pressure system A is installed, negative pressure regulating valve (24) and the switch A(25 of this negative pressure system A) be all positioned on guidance panel (6), on described rubber hose sucking head (10), negative pressure system B is installed, the switch B(28 of this negative pressure system B) be positioned on guidance panel (6).
2. the anticorrosion filling system of toy body tissue according to claim 1, it is characterized in that: described hydraulic system comprises hydraulic pressure active piston (18), the passive piston of hydraulic pressure (19), hydraulic line (20) and piston button (21), described hydraulic pressure active piston (18) is connected by hydraulic line (20) with the passive piston of hydraulic pressure (19), the external perfusion syringe needle of the passive piston of hydraulic pressure (19) (8), piston button (21) is connected with hydraulic pressure active piston (18).
3. the anticorrosion filling system of toy body tissue according to claim 1, it is characterized in that: described negative pressure system A comprises vacuum suction pump A(22), negative pressure sticking pipeline (23), negative pressure regulating valve (24) and switch A(25), switch A(25) with negative pressure regulating valve (24) all with vacuum suction pump A(22) be connected vacuum suction pump A(22) be connected with negative pressure holding head (9) by negative pressure sticking pipeline (23).
4. the anticorrosion filling system of toy body tissue according to claim 1, it is characterized in that: described negative pressure system B comprises vacuum suction pump B(26), negative pressure drainage pipeline (27), drainage bottle (29) and switch B(28), switch B(28) with vacuum suction pump B(26) be connected, negative pressure drainage vessel (29) is connected with rubber hose sucking head (10) by negative pressure drainage pipeline (27).
5. the anticorrosion filling system of toy body tissue according to claim 1, it is characterized in that: the distance between described perfusion syringe needle (8) and negative pressure holding head (9) is 0.1-0.5 centimetre, on described perfusion syringe needle (8), be covered with one deck scale layer, described negative pressure holding head (9) is bell-mouthed suction disk-like structure for end.
6. the anticorrosion filling system of toy body tissue according to claim 1, is characterized in that: a side of described perfusion support (2) is provided with the lifting platform (14) that can control height, and listerine bin (7) is placed on lifting platform (14).
7. the anticorrosion filling system of toy body tissue according to claim 1, it is characterized in that: between described operating board (5) and perfusion platform (1), be provided with the drainage trough (15) of " returning " font, the exit of this drainage trough (15) is provided with liquid waste collector (16).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320749832.4U CN203609541U (en) | 2013-11-25 | 2013-11-25 | Small animal whole-body tissue corrosion-prevention pouring system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320749832.4U CN203609541U (en) | 2013-11-25 | 2013-11-25 | Small animal whole-body tissue corrosion-prevention pouring system |
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| CN203609541U true CN203609541U (en) | 2014-05-28 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104568542A (en) * | 2014-12-30 | 2015-04-29 | 燕山大学 | Method for fixing fish brain tissue specimen through systemic heart perfusion |
| CN104644284A (en) * | 2015-02-26 | 2015-05-27 | 中国人民解放军第二军医大学 | Small animal perfusion sampling fixing device and small animal perfusion sampling fixing method |
| CN112716647A (en) * | 2020-12-31 | 2021-04-30 | 岳阳职业技术学院 | Little animal dissection workstation for biological function experiments |
-
2013
- 2013-11-25 CN CN201320749832.4U patent/CN203609541U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104568542A (en) * | 2014-12-30 | 2015-04-29 | 燕山大学 | Method for fixing fish brain tissue specimen through systemic heart perfusion |
| CN104644284A (en) * | 2015-02-26 | 2015-05-27 | 中国人民解放军第二军医大学 | Small animal perfusion sampling fixing device and small animal perfusion sampling fixing method |
| CN112716647A (en) * | 2020-12-31 | 2021-04-30 | 岳阳职业技术学院 | Little animal dissection workstation for biological function experiments |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140528 Termination date: 20141125 |
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| EXPY | Termination of patent right or utility model |