CN203576698U - Porous tantalum rod - Google Patents
Porous tantalum rod Download PDFInfo
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- CN203576698U CN203576698U CN201320598825.9U CN201320598825U CN203576698U CN 203576698 U CN203576698 U CN 203576698U CN 201320598825 U CN201320598825 U CN 201320598825U CN 203576698 U CN203576698 U CN 203576698U
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Abstract
The utility model relates to a medical permanent implantation object, in particular to a medical implantation porous tantalum rod used for treating early-mid femoral head necrosis. The porous tantalum rod comprises a body, wherein a groove is formed in one end of the body, the other end of the body is of a threaded structure, and a notch is formed in the end surface of the tail end of the threaded structure. According to the porous tantalum rod disclosed by the utility model, the groove is formed in one end of the body of the porous tantalum rod, bone marrow stromal stem cells or bone marrow stromal stem cells united biological membrane complexes and the like can be loaded, the porous tantalum rod is beneficial to generating a new bone, has a better clinical effect particularly in the early femoral head necrosis treatment, and overcomes the defects of poor clinical treatment effect and the like of the existing entity type porous tantalum rod.
Description
Technical field
This utility model relates to a kind of medical permanent implant, be particularly a kind ofly used for the treatment of early, mid-term femur head necrosis medical embedded porous tantalum rod.
Background technology
Femoral head articular step-off or femur head necrosis are clinical common diseases.At present the normal mode that adopts boring decompression is treated, and needs to refill to support after sequestrum is removed to subside or downright bad femoral head implant in operation process; In the treatment of middle and advanced stage femur head necrosis, current more employing is shifted treatment with or without the bone lobe of blood vessel, by a large amount of experiments and clinical confirmation, simple bone is transplanted and is had biomechanics underbraced, the shortcomings such as bone resorption, thereby the bone implant that can provide biomechanics to support need to be provided.
Porous medical metal implanted material has the important and special purposes such as treatment osseous tissue wound and bone formation necrosis, and existing this common class material has porous stainless steel, POROUS TITANIUM etc.As the porous embedded material of osseous tissue wound and the use of bone formation necrosis therapeutic, its porosity should reach 30-85%, and hole preferably all connected sums be uniformly distributed, or hole part connected sum is uniformly distributed as required, make it both consistent with the bone growth of human body, alleviate again the weight of material itself, to be applicable to human body, implanted use.
Metal tantalum, to side effect such as human body nonhazardouss, has good biocompatibility and mechanical property, and its porous material is expected to substitute aforementioned conventional medical metal biomaterial, becomes the main biomaterial in bone necrosis's treatment field.Along with the develop rapidly of domestic and international medical science, the further cognition to tantalum as body implanting material, to human body, implantation becomes more and more urgent by the demand of porous metals tantalum material to people, also more and more higher to its requirement., as the medical embedded metal tantalum of porous, if can there is the very high physical and mechanical properties that is uniformly distributed interconnected pore and adapts with human body, be wherein the heavy connection constituent material that guarantees freshman bone tissue's normal growth.
About this class material of porous tantalum, US5282861 discloses a kind of perforate tantalum material and preparation thereof that is applied to spongy bone implant, cell and organizes sensor.This porous tantalum is made by pure business tantalum, it carries out carbon skeleton that thermal degradation obtains as support take polyurethane precursor, this carbon skeleton is multiple dodecahedron, it in it, is mesh-like structure, entirety spreads all over micropore, porosity can be up to 98%, then commercially pure tantalum is attached on carbon skeleton to form porous metals micro structure by the method for chemical vapour deposition, infiltration, is called for short chemical deposition.Its surperficial tantalum layer thickness of the porous tantalum material that this method obtains is between 40-60 μ m; In whole porous material, tantalum proportion accounts for 99%, and carbon skeleton weight accounts for 1% left and right.Document is further recorded, the comprcssive strength 50-70MPa of this porous material, elastic modelling quantity 2.5-3.5GPa, tensile strength 63MPa, amount of plastic deformation 15%.But the porous tantalum using it as medical embedded material, the mechanical property of its material is obvious weak point as ductility has, and can have influence on the follow-up processing to porous tantalum material itself, the cutting of such as profiled member, boring etc.
At present, the medical implant for the filling of femur head necrosis position that adopts existing porous tantalum material to make, it is the screwed bar-shaped physical objects in a kind of one end, insider's custom is called " porous tantalum rod ", embedded implantation in clinical treatment, by the relief passage when the early stage row core decompression of femur head necrosis, implant, by surrounding bone tissue growth parcel and the mode such as grow into, be fixed, " the porous tantalum rod " of this result lacks the function of carrying the inducible factors such as bone marrow stroma stem cell and promoting the material of osteogenesis, thereby in treatment, often can not obtain good clinical effectiveness in early days, currently used " porous tantalum rod " is offshore company and produces and manufacture, expensive.In a word, the medical implant of this structure is not only expensive but also clinical success rate is lower, brings tremendous economic and psychological burden undoubtedly to extensive patients.
Utility model content
The purpose of this utility model be to provide a kind of cheap, there is the high tissue compatibility and biomechanical property, can induce osseous tissue to generate, be convenient to that osseous tissue grows into for medical embedded porous tantalum rod.
The technical solution of the utility model is as follows:
A kind of porous tantalum rod, comprises body, and one end of described body is provided with groove, and the other end is helicitic texture, in described helicitic texture distal end faces, is provided with notch.
In the technical solution of the utility model, the length of described groove is preferably 1～3:10, more preferably 1.5:10 with the ratio of body length.
In the technical solution of the utility model, in the width of described groove and body, the ratio of the diameter of non-threaded structure division is 4～7:10, more preferably 6:10.
In the technical solution of the utility model, reeded one end end face that arranges of described body is preferably hemisphere head.
In the technical solution of the utility model, described notch is preferably yi word pattern, cross or hexagon.
The shape of body described in the utility model is preferably cylindrical, but does not get rid of other shapes, according to the feature of implant site etc., can adopt any shape.
Porous tantalum rod of the present utility model, is provided with groove in one end of body, can load bone marrow stroma stem cell or bone marrow stroma stem cell associating biomembrane complex etc., serve as the carrier of cell, and induce the effects such as new osteogenesis.Described groove is positioned at front 1/3 part of body, be provided with the base side of hemisphere head end face, the length of described groove and width have certain ratio with length and the diameter of body respectively, to bring into play to greatest extent the effect of groove, be more conducive to load cells and keep the mechanical strength of barred body.On the other hand, the body part except groove is entity structure, and with respect to some have the porous tantalum rod of through hole at body center at present, the structure of this utility model porous tantalum rod has better mechanical strength.Described entity structure is to have the dodecahedron network structure that hole three-dimensional communication distributes, and is conducive to growing into of cell and tissue.
In further technical scheme of the present utility model, the porosity of the material that described porous tantalum rod body adopts is 70～90%, and aperture is 200～600 μ m.This material is the network structure that at least 50～95% polyhedron is interweaved, and has the dodecahedron network structure that hole three-dimensional communication distributes, and is conducive to growing into of cell and tissue.
Further, the material that described body adopts is coated on its surperficial tantalum metal by graphitic carbon skeleton and uniform deposition and forms, the porosity >70% of described graphitic carbon skeleton, and aperture is 200～600 μ m; The thickness of described tantalum coating is 40～60 μ m.
Further, the material that described body adopts prepares with the following method:
(1) by dilute hydrochloric acid etch 10min for graphitic carbon skeleton, after water and ethanol cleaning, with nitrogen, dry up successively, insert in reative cell;
(2) in reative cell, pass into simultaneously and process gas and hydrogen, at 900～1050 ℃, under vacuum 10Pa condition, react 4～6 hours; Wherein said processing gas comprises tantalum metallic compound and carrier gas, and tantalum metallic compound is put into carrying shield, is heated to 120～250 ℃, take high temperature inert gas as carrier gas, passes into reative cell, and the temperature of described high temperature inert gas is more than 300 ℃ or 300 ℃.
In above-mentioned preparation method, described tantalum metallic compound is tantalic chloride, fluoridize the one in tantalum; Described noble gas is preferably one or both the mixing in argon, helium; The flow of described processing gas is preferably 80～100ml/min; The flow of described hydrogen is 100～150ml/min.
Porous tantalum rod of the present utility model can be applied in early days, mid-term femoral head necrosis therapeutic medical implant.
The beneficial effects of the utility model: porous tantalum rod of the present utility model, one end at body is provided with groove, can load bone marrow stroma stem cell or bone marrow stroma stem cell associating biomembrane complex etc., be conducive to the generation of area of new bone, especially in early days in femoral head necrosis therapeutic, there is good clinical effectiveness, overcome the bad deficiency that waits of existing solid type " porous tantalum rod " effect on clinical treatment.On the other hand, the material of porous tantalum rod of the present utility model has dodecahedron space network, and its structure and Grafting Cancellous Bone Bolt girder are similar, have the high tissue compatibility, can induce osseous tissue to generate, and is convenient to growing into of osseous tissue; And there is stronger biomechanical property, and can provide certain mechanics to support, reach the object of preventing or delaying collapse of the femoral head.Porous tantalum rod of the present utility model, preparation method is simple, cost is low, is conducive to implement and clinical practice, is suitable for the needs of extensive patients.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the utility model is described in further detail:
Fig. 1 is the front view of porous tantalum rod of the present utility model
Fig. 2 is the left view of porous tantalum rod of the present utility model
Fig. 3 is the top view of porous tantalum rod of the present utility model
Fig. 4 is that porous tantalum rod is implanted schematic diagram in femur head necrosis intermediate period treatment
Drawing reference numeral: 1, body, 2, groove, 3, helicitic texture, 4, notch, 5, femoral head subsides
The specific embodiment
Following non-limiting example can make those of ordinary skill in the art's comprehend this utility model, but limits never in any form this utility model.
Embodiment 1
As shown in Figure 1 to Figure 3, a kind of porous tantalum rod, it comprises body 1, one end of described body 1 is provided with groove 2, the other end is helicitic texture 3, in described helicitic texture 3 distal end faces, be provided with notch 4, one end end face that is provided with groove 2 of described body 1 is hemisphere head, and described body 1 is cylindric.The length of described groove 2 is 1.5:10 with the ratio of body 1 length; In the width of described groove 2 and body 1, the ratio of the diameter of non-threaded structure 3 parts is 6:10.
On the other hand, in concrete use, according to features such as the size of implant site, tissues, can suitably regulate the concrete size of described body (being porous tantalum rod), to reach best therapeutic effect.
Described porous tantalum rod is provided with groove 2 in one end of body, can load bone marrow stroma stem cell or bone marrow stroma stem cell associating biomembrane complex etc., serve as the carrier of cell, and induce the effects such as new osteogenesis.
In described helicitic texture 3 distal end faces, be provided with notch 4, be convenient to installing and using of operation tool.Described notch 4 can be cross, can be also yi word pattern or hexagon.While implanting this porous tantalum rod in osseous tissue, spiral shell cutter screws in implantation piece by means of notch 4.
As shown in Figure 1 to Figure 3, a kind of porous tantalum rod, it comprises body 1, one end of described body 1 is provided with groove 2, the other end is helicitic texture 3, in described helicitic texture 3 distal end faces, be provided with notch 4, one end end face that is provided with groove 2 of described body 1 is hemisphere head, and described body 1 is cylindric.The length of described groove 2 is 1.5:10 with the ratio of body 1 length; In the width of described groove 2 and body 1, the ratio of the diameter of non-threaded structure 3 parts is 6:10.
On the other hand, in concrete use, according to features such as the size of implant site, tissues, can suitably regulate the concrete size of described body (being porous tantalum rod), to reach best therapeutic effect.
Described porous tantalum rod is provided with groove 2 in one end of body, can load bone marrow stroma stem cell or bone marrow stroma stem cell associating biomembrane complex etc., serve as the carrier of cell, and induce the effects such as new osteogenesis.
In described helicitic texture 3 distal end faces, be provided with notch 4, be convenient to installing and using of operation tool.Described notch 4 can be cross, can be also yi word pattern or hexagon.While implanting this porous tantalum rod in osseous tissue, spiral shell cutter screws in implantation piece by means of notch 4.
The porous tantalum material that the body 1 of described porous tantalum rod adopts is to utilize chemical gaseous phase depositing process, tantalum metallic compound is reduced to tantalum metal powder, uniform deposition forms tantalum coating in graphitic carbon skeleton surface and prepares, and wherein said tantalum metallic compound is tantalic chloride; The porosity 85% of described graphitic carbon skeleton, aperture is 500 μ m; The thickness of described tantalum coating is 40～60 μ m.
The concrete preparation method of the porous tantalum material of described porous tantalum rod is as follows:
(1) by dilute hydrochloric acid etch 10min for described graphitic carbon skeleton, after water and ethanol cleaning, with nitrogen, dry up successively, insert in reative cell;
(2) by particle diameter, be that 400 object pentachloro-carbon dusts are put into carrying shield, be heated to 150 ℃, take high temperature argon (300 ℃) as carrier gas, pass into reative cell, carrier gas flux is 100ml/min, and reaction chamber temperature is 1050 ℃, and reative cell vacuum is 10Pa; In reative cell, pass into when passing into tantalic chloride powder take argon as carrier gas, with 120ml/min flow, pass into hydrogen, reduction reaction 4 hours, makes the tantalum metal uniform deposition that is reduced into metal dust in graphitic carbon skeleton surface and its surface, space, obtains medical porous tantalum finished material of the present invention.
The porosity of porous tantalum finished material is 85%, elastic modelling quantity is 10GPa, maximum compressive strength is 35MPa., and wherein porosity is according to standard GB/T/T21650.1-2008, and elastic modelling quantity is to detect according to the method described in standard GB/T/T22315-2008.
Described porous tantalum material, has the dodecahedron network structure that hole three-dimensional communication distributes, and its structure and Grafting Cancellous Bone Bolt girder are similar, have the high tissue compatibility, can induce osseous tissue to generate, and is convenient to growing into of osseous tissue; And there is stronger biomechanical property, and can provide certain mechanics to support, reach the object of preventing or delaying collapse of the femoral head.
In above-mentioned preparation method, if no special instructions, the experimental technique using is conventional method, and agents useful for same Deng Junkecong chemical reagents corporation buys.Described graphitic carbon skeleton is commercial product, can buy on the market.The general Colophonium that adopts carries out high-temperature process as substrate, adds foam, thereby obtain even porous dodecahedron celion skeleton in process.
In above-mentioned preparation method, first graphitic carbon skeleton is processed into the shape described in Fig. 1～Fig. 3, then through step (1)～(2), prepared porous tantalum rod.
Embodiment 3 application of porous tantalum rod in femur head necrosis intermediate period treatment
Get otch outside hip, rise from 2cm place, anterior superior iliac spine outer lower side, to greater trochanter of femur direction, extend, one-tenth a pair of serpentine otch, is about as 8-12cm.In its dark facial muscle matter, finding is ascending branch of lateral circumflex femoral vessels, drives in the wrong direction and is separated to tensor fasciae latae musculus lateralis interni door, and blunt separation is to anterior superior iliac spine, separation process will be with about 1cm left and right flesh sleeve, osteotome cuts iliac bone lobe about 2.0cm × 2.5cm × 2.0cm size, and the spongy bone that takes a morsel, standby.In femoral head neck intersection, with osteotome, window, the about 2.0cm × 2.0cm of area, removes necrotic bone tissue in femoral head, and in the illiac bone flap cutting to femoral head is windowed, suitable power compacting, rises the femoral head subsiding 5.Insert guide pin, with 10 degree-15 degree top rakes, from the entry point designing, pierce femoral head, the about 5mm of distance articular surface place on through x-ray lateral projection, at this moment must carry out positive side position perspective with c arm x line machine, determines the tram of guide pin.Kuo Ding road, depth measurement, extract guide pin, with depth finder Ce Ding road length.After tapping, screw in porous tantalum rod of the present invention, the bone lobe of transfer is risen, increase the mechanical stress support of shifting bone lobe, place the generation of again subsiding.In aforesaid operations, according to the testing result of sounder Dui Ding road length, determine the porous tantalum metal bar implant that adopts different length.The concrete porous tantalum rod using is of a size of as follows: body 1 total length is 10cm, and diameter is 1cm; The total length of helicitic texture 3 is 2cm, and diameter is 1.2cm; The total length of groove 2 is 1.5cm, and width is 0.6cm, and the distance of the hemisphere head end face of groove 2 front ends and body 1 is 0.5cm.
Claims (5)
1. a porous tantalum rod, comprises body (1), and one end of described body (1) is provided with groove (2), and the other end is helicitic texture (3), in described helicitic texture (3) distal end faces, is provided with notch (4); The porosity of the material that described body (1) adopts is 70～90%, and aperture is 200～600 μ m; The material that described body (1) adopts is coated on its surperficial tantalum metal by graphitic carbon skeleton and uniform deposition and forms, the porosity >70% of described graphitic carbon skeleton, and aperture is 200～600 μ m; The thickness that described uniform deposition is coated on the tantalum metal on graphitic carbon skeleton surface is 40～60 μ m.
2. porous tantalum rod according to claim 1, is characterized in that, the ratio of the length of described groove (2) and body (1) length is 1～3:10.
3. porous tantalum rod according to claim 1, is characterized in that, in the width of described groove (2) and body, the ratio of the diameter of non-threaded structure (3) part is 4～7:10.
4. porous tantalum rod according to claim 1, is characterized in that, one end end face that is provided with groove (2) of described body (1) is hemisphere head.
5. porous tantalum rod according to claim 1, is characterized in that, described notch (4) is yi word pattern, cross or hexagon.
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| CN201320598825.9U CN203576698U (en) | 2013-09-26 | 2013-09-26 | Porous tantalum rod |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105769390A (en) * | 2016-05-29 | 2016-07-20 | 王跃文 | Honeycomb core decompression surgery implantation nail |
| WO2017063425A1 (en) * | 2015-10-15 | 2017-04-20 | 赵德伟 | Porous tantalum metal bone connector and application thereof |
| CN108210120A (en) * | 2016-12-21 | 2018-06-29 | 重庆润泽医药有限公司 | A kind of tantalum bar device |
| CN108210118A (en) * | 2016-12-21 | 2018-06-29 | 重庆润泽医药有限公司 | Tantalum bar system |
| CN108236517A (en) * | 2016-12-23 | 2018-07-03 | 重庆润泽医药有限公司 | A kind of operation tantalum bar device |
| CN108236514A (en) * | 2016-12-23 | 2018-07-03 | 重庆润泽医药有限公司 | Operation tantalum bar system |
| CN108245283A (en) * | 2016-12-28 | 2018-07-06 | 重庆润泽医药有限公司 | Orthopedic operating tantalum bar device |
| CN108245282A (en) * | 2016-12-28 | 2018-07-06 | 重庆润泽医药有限公司 | Orthopedic operating tantalum stick equipment |
| CN108245284A (en) * | 2016-12-28 | 2018-07-06 | 重庆润泽医药有限公司 | Orthopedic operating tantalum bar system |
| CN108261262A (en) * | 2016-12-30 | 2018-07-10 | 重庆润泽医药有限公司 | A kind of small-sized orthopedic operating tantalum stick equipment |
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2013
- 2013-09-26 CN CN201320598825.9U patent/CN203576698U/en not_active Expired - Lifetime
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017063425A1 (en) * | 2015-10-15 | 2017-04-20 | 赵德伟 | Porous tantalum metal bone connector and application thereof |
| CN105769390A (en) * | 2016-05-29 | 2016-07-20 | 王跃文 | Honeycomb core decompression surgery implantation nail |
| CN108210120A (en) * | 2016-12-21 | 2018-06-29 | 重庆润泽医药有限公司 | A kind of tantalum bar device |
| CN108210118A (en) * | 2016-12-21 | 2018-06-29 | 重庆润泽医药有限公司 | Tantalum bar system |
| CN108236517A (en) * | 2016-12-23 | 2018-07-03 | 重庆润泽医药有限公司 | A kind of operation tantalum bar device |
| CN108236514A (en) * | 2016-12-23 | 2018-07-03 | 重庆润泽医药有限公司 | Operation tantalum bar system |
| CN108245283A (en) * | 2016-12-28 | 2018-07-06 | 重庆润泽医药有限公司 | Orthopedic operating tantalum bar device |
| CN108245282A (en) * | 2016-12-28 | 2018-07-06 | 重庆润泽医药有限公司 | Orthopedic operating tantalum stick equipment |
| CN108245284A (en) * | 2016-12-28 | 2018-07-06 | 重庆润泽医药有限公司 | Orthopedic operating tantalum bar system |
| CN108261262A (en) * | 2016-12-30 | 2018-07-10 | 重庆润泽医药有限公司 | A kind of small-sized orthopedic operating tantalum stick equipment |
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Effective date of registration: 20220302 Address after: Department of orthopedics, Zhongshan Hospital Affiliated to Dalian University, No.6 Jiefang street, Zhongshan District, Dalian, Liaoning, 116001 Patentee after: Zhao Dewei Address before: 116001 Department of orthopedics, Zhongshan Hospital Affiliated to Dalian University, No. 6 Jiefang street, Zhongshan District, Dalian City, Liaoning Province Patentee before: Zhao Dewei Patentee before: Wang Benjie Patentee before: Wei Xiao Wei Patentee before: Xie Hui Patentee before: Huang Shibo Patentee before: Wang Wei |
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Effective date of registration: 20230725 Address after: Room 201, 2nd Floor, Huatang Building, No. 203 Jinma Road, Economic and Technological Development Zone, Dalian City, Liaoning Province, 116600 Patentee after: Weitan (Dalian) Biomaterials Co.,Ltd. Address before: Department of orthopedics, Zhongshan Hospital Affiliated to Dalian University, No.6 Jiefang street, Zhongshan District, Dalian, Liaoning, 116001 Patentee before: Zhao Dewei |
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