CN203539464U - Dental implant - Google Patents
Dental implant Download PDFInfo
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- CN203539464U CN203539464U CN201320651701.2U CN201320651701U CN203539464U CN 203539464 U CN203539464 U CN 203539464U CN 201320651701 U CN201320651701 U CN 201320651701U CN 203539464 U CN203539464 U CN 203539464U
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- Prior art keywords
- groove
- neck ring
- dental implant
- implant
- fibroblast
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- 239000004053 dental implant Substances 0.000 title abstract 7
- 239000011248 coating agent Substances 0.000 claims abstract description 26
- 238000000576 coating method Methods 0.000 claims abstract description 26
- NRTOMJZYCJJWKI-UHFFFAOYSA-N Titanium nitride Chemical compound [Ti]#N NRTOMJZYCJJWKI-UHFFFAOYSA-N 0.000 claims abstract description 23
- 239000007943 implant Substances 0.000 claims abstract description 21
- 238000002513 implantation Methods 0.000 claims description 29
- 238000003754 machining Methods 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 14
- 210000002950 fibroblast Anatomy 0.000 abstract description 14
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 11
- 230000006698 induction Effects 0.000 abstract description 9
- 230000005012 migration Effects 0.000 abstract description 5
- 238000013508 migration Methods 0.000 abstract description 5
- 239000008280 blood Substances 0.000 abstract description 4
- 210000004369 blood Anatomy 0.000 abstract description 4
- 230000002093 peripheral effect Effects 0.000 abstract description 4
- 210000004872 soft tissue Anatomy 0.000 abstract description 4
- 230000004913 activation Effects 0.000 abstract description 3
- 239000002103 nanocoating Substances 0.000 abstract description 3
- 230000008952 bacterial invasion Effects 0.000 abstract description 2
- 230000007774 longterm Effects 0.000 abstract description 2
- 230000035755 proliferation Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 23
- 239000010936 titanium Substances 0.000 description 15
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 14
- 229910052719 titanium Inorganic materials 0.000 description 14
- 238000000034 method Methods 0.000 description 9
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 8
- 229910052710 silicon Inorganic materials 0.000 description 8
- 239000010703 silicon Substances 0.000 description 8
- 230000012010 growth Effects 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 210000002808 connective tissue Anatomy 0.000 description 6
- 238000013461 design Methods 0.000 description 5
- 238000001259 photo etching Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 238000005530 etching Methods 0.000 description 4
- 238000001755 magnetron sputter deposition Methods 0.000 description 4
- 230000003239 periodontal effect Effects 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 241000605862 Porphyromonas gingivalis Species 0.000 description 2
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000010478 bone regeneration Effects 0.000 description 2
- 210000002919 epithelial cell Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000010118 platelet activation Effects 0.000 description 2
- 108010087230 Sincalide Proteins 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010609 cell counting kit-8 assay Methods 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 210000004292 cytoskeleton Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000005081 epithelial layer Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000007773 growth pattern Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000010166 immunofluorescence Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 239000012779 reinforcing material Substances 0.000 description 1
- IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Cosmetics (AREA)
Abstract
The utility model discloses a dental implant which is technically characterized in that a groove is formed on the surface of a neck ring of the implant. A titanium nitride (TiN) coating is arranged on the surface of the groove, and is 100-1000nm thick. A surface feature of anisotropism of the horizontal groove of the dental implant is capable of generating a contact induction effect on gingival fibroblast, which means that the fibroblast can be guided to grow along the direction of the horizontal groove. Forming of a peripheral seal of the dental implant by the gingival fibroblast is facilitated due to the contact induction effect, which means that the fibroblast can be guided to grow along the horizontal trend of the groove to accelerate well union of surrounding soft tissues of the dental implant and prevent epithelial migration with the direction and bacterial invasion, so as to realize peripheral seal of the implant and ensure the long-term stability of the implant. The micro-groove is combined with the TiN nano coating, so that the dental implant has good antibacterial property and good blood compatibility, effectively accelerates platelet adhesiveness and activation, and has good biocompatibility. Meanwhile, the dental implant effectively promotes proliferation and adhesion of the gum fibroblast.
Description
Technical field
This utility model relates to implantation body, especially belongs to tooth implant.
Background technology
The application of titanium implant has at present become the conventional method that substitutes missing tooth, the epithelial layer that the connective tissue layer that bone regeneration around implant soft tissue mainly consists of Gingival Fibroblasts and epithelial cell form forms, as shown in Figure 1, thereby smooth neck ring 11 peripheral cells of traditional implantation body 1 have trend and the connective tissue of with side's migration, growing to be combined into it the growth that parallel attachment relationship is different from natural periodontal tissue embedding tooth body, therefore weakened implantation body and the binding ability of connective tissue around, tradition thinks that coarse neck ring can cause the adhesion of antibacterial around simultaneously, and be unfavorable for that patient recovers.
Summary of the invention
The purpose of this utility model is to provide a kind of can better realize implantation body's border seal, stops antibacterial to be invaded, and guarantees the tooth implant of implantation body's long-time stability.
The technical scheme that this utility model adopts is a kind of tooth implant, and its technical essential is there is groove in implantation body's neck ring Surface Machining.
Think traditionally because coarse neck ring surface area is large, the place that antibacterial can adhere to is large, be unfavorable for that patient recovers, and ignored smooth neck ring peripheral cell, there is the trend with side's migration growth, and connective tissue is combined into it parallel attachment relationship, thereby be different from the growth that natural periodontal tissue embeds tooth body, therefore implantation body and the binding ability of connective tissue have around been weakened.The surface character of horizontal channel " anisotropy " can produce to Gingival Fibroblasts " contact induction " effect, can guide cell along the direction growth of horizontal channel, this utility model has the micro-groove of level perpendicular to implantation body's major axis in implantation body's neck ring Surface Machining, utilize " contact induction " effect to stop the epithelial cell root side migration of Gingival Fibroblasts and top, be conducive to plant the combination of cervical region and surrounding soft tissue, prevent bacterial invasion, realize implantation body's border seal, the growth pattern that embeds tooth body with natural periodontal tissue is similar, guarantee that implantation body is steady in a long-term.
Flute surfaces has titanium nitride (TiN) coating.This utility model utilize titanium nitride (TiN) coating increase implantation body's neck ring around antibacterial ability and the blood compatibility of reinforcing material.
The thickness that flute surfaces has titanium nitride (TiN) coating is 100-1000nm.Titanium nitride (TiN), as its stable chemical performance of nano coating, has stronger wear-resistant corrosion resistance and good biocompatibility and antibiotic property.Coating based on spraying can cover all flute surfaces does not affect again original groove structure simultaneously, and the sputter thickness of titanium nitride coating is defined as 100-1000nm.
Multiple tracks groove parallel interval distributes.Be conducive to inducing cell regularly arranged along the runs parallel of groove.
Multiple tracks groove is uniformly-spaced uniformly distributed.Easy to make, be conducive to cell and be subject to uniformly deformation stimulation cytoskeleton being caused same widths groove ridge top, make cell be subject to keeping relatively consistent biological aspect after pattern effect as far as possible.
Ditch grooved profile is trapezoidal or rectangle.Conventionally ditch grooved profile is that outer imperial palace is little, and base inverted trapezoidal or rectangle outwardly, to guide cell inwardly to grow and realize implantation body's border seal along groove, stops antibacterial to be invaded.
Trenched side-wall and neck ring surface angle are 45 °-90 °, and certain slope guarantees the realization of " contact induction " effect.
On implantation body's neck ring surface, be uniformly-spaced processed with the parallel groove of multiple tracks, the width 50-100 μ m of groove, spacing 50-100 μ m, degree of depth 10-15 μ m, trenched side-wall and neck ring surface angle are 45 °-90 °, groove vertical section be shaped as inverted trapezoidal or rectangle, flute surfaces has the titanium nitride that thickness is 100-1000nm (TiN) coating.
Studies have shown that in order to guarantee the existence of groove pattern to cell " contact induction " effect, groove width and groove space requirement are no more than the size of exposing cell with it, require gash depth to be not less than 10 μ m simultaneously, implantation body's neck ring around connective tissue Gingival Fibroblasts size is (110 μ m), in order to meet cell, can when growing, groove also can enter groove growth, the width of groove and the interval of groove are defined as 50-100 μ m, in order to guarantee the quality of follow-up titanium nitride spraying, gash depth is 10-15 μ m.
On implantation body's neck ring surface, be uniformly-spaced processed with the parallel groove of multiple tracks, the width 60 μ m of groove, spacing 60 μ m, the degree of depth 10 μ m, trenched side-wall and neck ring surface angle is 54.74 °, groove vertical section be shaped as inverted trapezoidal, titanium nitride (TiN) coating of flute surfaces sputter 200nm.
The surface character of horizontal channel of the present utility model " anisotropy " can produce to Gingival Fibroblasts " contact induction " effect in summary, can guide cell along the direction growth of horizontal channel, by " contact induction " effect, be conducive to Gingival Fibroblasts and form implantation body's border seal, can guide cell to move towards growth along groove level, accelerate the good healing of bone regeneration around implant soft tissue, stop epithelium with side's migration, antibacterial is invaded, realize implantation body's border seal, guarantee implantation body's long-time stability.Micro-groove contact TiN nano coating has good antibiotic property, has good blood compatibility, effectively promotes platelet adhesion and activation, has good biocompatibility, has effectively promoted propagation and the adhesion of Gingival Fibroblasts simultaneously.
Accompanying drawing explanation
Fig. 1 is the structural representation of existing implantation body
Fig. 2 is structural representation of the present utility model
Fig. 3 is the partial enlarged drawing at Fig. 2 A place
Fig. 4 be the B of Fig. 3 to expansion, cell growth state schematic diagram
Wherein: 1 implantation body's 11 neck ring 12 groove 2 cells.
The specific embodiment
Below in conjunction with view, this utility model is described in detail, makes professional and technical personnel more understand this utility model, but do not limit in any form this utility model.
A tooth implant, is to improve on the basis of existing tooth implant, in smooth tooth implant neck ring 11 Surface Machining, has groove 12, and flute surfaces has titanium nitride (TiN) coating.Conventionally on implantation body's neck ring 11 surfaces, be uniformly-spaced processed with the parallel groove of multiple tracks 12, the width 50-100 μ m of groove 12, spacing 50-100 μ m, degree of depth 10-15 μ m, trenched side-wall and neck ring surface angle are 45 °-90 °, and groove longitudinal profile is shaped as inverted trapezoidal or rectangle, and described inverted trapezoidal refers to that outer imperial palace is little, be outwardly trapezoidal of base, the thickness of flute surfaces sputter titanium nitride (TiN) coating is 100-1000nm.
Adopt photoetching technique, the mask plate that design is identical with spacing with institute etched trench width, by mask plate, control width and the spacing of groove on silicon plate, by etching period, control gash depth on silicon plate, realization is uniformly-spaced evenly distributed with the micro-groove of multiple tracks on the smooth neck ring of implantation body surface: width 60 μ m, groove pitch 60 μ m, the degree of depth 10 μ m, groove vertical section is inverted trapezoidal, trenched side-wall and neck ring surface angle are 54.74 °, titanium (Ti) coating by magnetron sputtering technique at flute surfaces spraying 200nm.
Embodiment 2
Adopt photoetching technique, the mask plate that design is identical with spacing with institute etched trench width, by mask plate, control width and the spacing of groove on silicon plate, by etching period, control gash depth on silicon plate, realization is uniformly-spaced evenly distributed with the micro-groove of multiple tracks on the smooth neck ring of implantation body surface: width 60 μ m, groove pitch 60 μ m, the degree of depth 10 μ m, groove vertical section is inverted trapezoidal, trenched side-wall and neck ring surface angle are 54.74 °, titanium nitride (TiN) coating by magnetron sputtering technique at flute surfaces sputter 200nm.
Embodiment 3
Adopt photoetching technique, the mask plate that design is identical with spacing with institute etched trench width, by mask plate, control width and the spacing of groove on silicon plate, by etching period, control gash depth on silicon plate, realization is uniformly-spaced evenly distributed with the micro-groove of multiple tracks on the smooth neck ring of implantation body surface: width 50 μ m, groove pitch 100 μ m, the degree of depth 13 μ m, groove vertical section is inverted trapezoidal, trenched side-wall and neck ring surface angle are 54.74 °, titanium nitride (TiN) coating by magnetron sputtering technique at flute surfaces sputter 300nm.
Embodiment 4
Adopt photoetching technique, the mask plate that design is identical with spacing with institute etched trench width, by mask plate, control width and the spacing of groove on silicon plate, by etching period, control gash depth on silicon plate, realization is distributed with the micro-groove of multiple tracks at the smooth neck ring surface uniform of implantation body: width 100 μ m, groove pitch 50 μ m, the degree of depth 15 μ m, groove vertical section is inverted trapezoidal, trenched side-wall and neck ring surface angle are 54.74 °, titanium nitride (TiN) coating by magnetron sputtering technique at flute surfaces sputter 420nm.
The beneficial effects of the utility model
In experiment, matched group smooth titanium neck ring is the pure titanium that business is used
1) adopt CCK-8 experiment, by solution, at the absorbance of OD450, reflect that cell is in the propagation situation of material surface
People's Gingival Fibroblasts is in the propagation result (OD450 absorbance) of different materials surface different time points
| Grouping | 6H | 1D | 3D | 5D | 7D |
| Smooth titanium neck ring | 0.068±0.003 | 0.239±0.034 | 0.402±0.027 | 0.734±0.031 | 0.529±0.076 |
| |
0.110±0.002 | 0.432±0.027 | 0.644±0.022 | 1.045±0.182 | 1.664±0.109 |
| Embodiment 2 | 0.129±0.004 | 0.531±0.078 | 0.936±0.078 | 1.454±0.103 | 2.123±0.123 |
| Embodiment 3 | 0.126±0.031 | 0.511±0.062 | 0.809±0.052 | 1.343±0.102 | 2.011±0.140 |
| Embodiment 4 | 0.131±0.038 | 0.581±0.085 | 0.999±0.064 | 1.543±0.132 | 2.451±0.153 |
Experimental result surface this utility model has the effect of obvious promotion Gingival Fibroblasts propagation at different time points compared with smooth titanium material, the effect of titanium nitride coating is more effective than titanium coating.
2) adopt immunofluorescence characterize cells form, by cell arrangement angle as shown in Figure 4 the major axis of cell 2 and the angle of groove horizontal direction (being the cross section of groove) in the shared ratio characterize cells of 0 ° of-10 ° of cell the growing state along groove horizontal direction
Different materials superficial cell is arranged angle in 0 ° of-10 ° of ratio that cell is shared (%)
| Group | 6H | 1D |
| Smooth titanium neck ring | 19.8±3.32 | 34.2±3.14 |
| |
89.3±1.53 | 95.3±1.03 |
| Embodiment 2 | 89.4±1.87 | 95.7±0.99 |
| Embodiment 3 | 86.3±1.68 | 94.2±1.02 |
| Embodiment 4 | 90.3±1.72 | 97.7±0.91 |
Result shows that this utility model superficial cell arranges angle and obviously increase the ratio of 0 °-10 °, and this utility model starts that from the adhesion initial stage cell is just had to good " contact induction " effect.
3) by flow cytometer, detect the sign (MP, P-selection) of platelet activation, the platelet that the higher explanation of percentage ratio is activated is more
The percentage ratio (%) of different materials surface indices of activated platelet activation
| Group | MP | P-selection |
| Smooth titanium neck ring | 16.89±0.175 | 5.67±0.231 |
| |
20.32±0.208 | 7.98±0.162 |
| Embodiment 2 | 24.87±0.151 | 13.48±0.086 |
| Embodiment 3 | 23.00±0.251 | 14.48±0.198 |
| Embodiment 4 | 22.07±0.191 | 13.48±0.260 |
Result shows that the more traditional smooth titanium of this utility model surface has promoted hematoblastic activation, has improved blood compatibility, and the effect of titanium nitride coating is more effective than titanium coating.
4), by the live antibacterial ability of Bacterial stain counting exosyndrome material of external porphyromonas gingivalis, the antibacterial number of surface adhesion bright its antibacterial ability of more speaking more is more weak
Different materials surface porphyromonas gingivalis counting (10 alive
5individual)
| Group | 6h | 1D |
| Smooth titanium neck ring | 0.71±0.12 | 9.96±0.98 |
| |
0.56±0.14 | 6.23±0.44 |
| Embodiment 2 | 0.35±0.17 | 3.41±0.25 |
| Embodiment 3 | 0.29±0.09 | 2.83±0.31 |
| Embodiment 4 | 0.38±0.11 | 3.98±0.45 |
Result shows that the more traditional smooth titanium of this utility model has anti-bacterial attachment function, and the effect of titanium nitride coating is better than titanium coating.
The above is only preferred implementation of the present utility model; each design parameter can carry out multiple choices in the situation that not changing this utility model aim; for those skilled in the art; the improvement of making within not departing from essential scope of the present utility model, replacement and retouching, also should belong to protection domain of the present utility model.Any Technology that can form micro-groove pattern all can apply to make the groove that meets size restrictions, any technology that can spray titanium nitride coating can apply to form the coating that meets thickness limits, the current restriction because of photoetching technique, embodiment only provides the inverted trapezoidal that is shaped as in groove vertical section, for example, after laser micro-machining technology maturation, also can apply to make the embodiment that is shaped as rectangle in groove vertical section.
Claims (8)
1. a tooth implant, is characterized in that: in implantation body's neck ring (11) Surface Machining, have groove (12).
2. according to a kind of tooth implant described in claims 1, it is characterized in that: on groove (12) surface, there is titanium nitride coating.
3. according to a kind of tooth implant described in claims 1, it is characterized in that: multiple tracks groove (12) parallel interval distributes.
4. according to a kind of tooth implant described in claims 2, it is characterized in that: multiple tracks groove (12) is uniformly-spaced uniformly distributed.
5. according to a kind of tooth implant described in claims 1, it is characterized in that: groove (12) vertical section is shaped as trapezoidal or rectangle.
6. according to a kind of tooth implant described in claims 1, it is characterized in that: the thickness that flute surfaces has titanium nitride coating is 100-1000nm.
7. according to a kind of tooth implant described in claims 1, it is characterized in that: on implantation body's neck ring (11) surface, be uniformly-spaced processed with the parallel groove of multiple tracks (12), the width 50-100 μ m of groove (12), spacing 50-100 μ m, degree of depth 10-15 μ m, trenched side-wall and neck ring surface angle are 45 °-90 °, and groove vertical section is shaped as inverted trapezoidal or rectangle, and flute surfaces has the titanium nitride coating that thickness is 100-1000nm.
8. according to a kind of tooth implant described in claims 7, it is characterized in that: on implantation body's neck ring (11) surface, be uniformly-spaced processed with the parallel groove of multiple tracks (12), the width 60 μ m of groove (12), spacing 60 μ m, the degree of depth 10 μ m, trenched side-wall and neck ring surface angle be good at 57.74 °, groove vertical section be shaped as inverted trapezoidal, flute surfaces sprays the titanium nitride coating of 200nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320651701.2U CN203539464U (en) | 2013-10-22 | 2013-10-22 | Dental implant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320651701.2U CN203539464U (en) | 2013-10-22 | 2013-10-22 | Dental implant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203539464U true CN203539464U (en) | 2014-04-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320651701.2U Expired - Lifetime CN203539464U (en) | 2013-10-22 | 2013-10-22 | Dental implant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203539464U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519911A (en) * | 2013-10-22 | 2014-01-22 | 福建医科大学附属口腔医院 | Dental implant |
| CN113679495A (en) * | 2021-06-17 | 2021-11-23 | 北京万嘉高科医药科技有限公司 | Tooth implant with nanometer antibacterial structure ring at gum penetrating part and processing method thereof |
-
2013
- 2013-10-22 CN CN201320651701.2U patent/CN203539464U/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519911A (en) * | 2013-10-22 | 2014-01-22 | 福建医科大学附属口腔医院 | Dental implant |
| CN103519911B (en) * | 2013-10-22 | 2016-04-13 | 福建医科大学附属口腔医院 | Tooth implant |
| CN113679495A (en) * | 2021-06-17 | 2021-11-23 | 北京万嘉高科医药科技有限公司 | Tooth implant with nanometer antibacterial structure ring at gum penetrating part and processing method thereof |
| CN113679495B (en) * | 2021-06-17 | 2022-09-16 | 北京万嘉高科医药科技有限公司 | Tooth implant with nanometer antibacterial structure ring at gum penetrating part and processing method thereof |
| US11890165B2 (en) | 2021-06-17 | 2024-02-06 | Beijing Vanjewel Medical Tech Co., Ltd | Dental implant with nano bacteriostatic structure ring at transgingival part and machining method thereof |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
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Granted publication date: 20140416 |