CN203534868U - Biosensor - Google Patents
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- CN203534868U CN203534868U CN201320729286.8U CN201320729286U CN203534868U CN 203534868 U CN203534868 U CN 203534868U CN 201320729286 U CN201320729286 U CN 201320729286U CN 203534868 U CN203534868 U CN 203534868U
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Images
Abstract
The utility model discloses a biosensor which comprises a sensor body and at least two electrodes, wherein one end of the sensor body is an acquisition end; the other end of the sensor body is an electric contact end; a groove used as a liquid sample chamber is formed in the acquisition end; the length of the opening of the groove is greater than or equal to half of the length of the end surface of the acquisition end; the electrodes are positioned inside the sensor body; one end of each electrode is communicated with the interior of the groove; the other end of each electrode is positioned at the electric contact end; chemical agents cover the electrodes and are used for reacting with a liquid sample to generate testable electrochemical signals. According to the biosensor, as the length of the opening of the groove is large, and a super-wide sample inlet is formed, blood can be easily aligned with a micro sample when being sucked into the liquid sample chamber, a small amount of samples dispersed on the surface of skin can be also easily sucked, the problem that an opening end is blocked is solved, and the problem that the testing result is not correct due to the fact that the sample inside the liquid sample chamber is not sufficiently filled and the sample is not continuously sucked during detection is solved.
Description
Technical field
The utility model relates to medical analytical instrument technical field, particularly a kind of biology sensor.
Background technology
As everyone knows, at medical field, disposable biological sensor (as examination bar) has been widely used in measuring the multiple analytes in body fluid.When diagnosing some physically different, to the quantitative measurement of some analyte in body fluid, be very important.For example: blood sugar test result can be used for judging whether to give insulin or other drug is treated.Therefore,, particularly for diabetes patient, it is very important by the blood sugar level in frequent detection body fluid, managing the glucose amount of taking in diet.In a certain class blood sugar test system, be (or to be called: blood sugar examination bar) test the concentration of glucose in blood sample, the bar of blood sugar examination has at present become many diabetics' various daily neces saries all over the world with biology sensor.
The blood sugar of existing a lot of brands examination bar on market, these blood sugar examination bars are structurally very similar, are all, in the middle of examination bar, an elongated passageway is set conventionally, and passage one end is positioned at the openend of examination bar, be used for gathering blood, the other end is as the exhausr port of discharging air when the blood sample collection.When the openend from examination bar gathers blood, due to capillary action, the blood collecting is inhaled in this passage, and the air in passage is discharged from exhausr port simultaneously.In order to reduce the required blood sample amount that detects, the pain when puncturing finger or other sampled points and get blood to alleviate, the space of the fluid sample chamber in existing examination bar (i.e. the passage for taking a blood sample) is conventionally very little, and this causes sample inlet also smaller comparatively speaking.
Yet the space, fluid sample chamber on biology sensor is less, can makes analyzed sample be full of fluid sample chamber and become comparatively difficult.According to applicant's clinical observation, find, the sampling that finger may be withstood to sensor when user uses is most advanced and sophisticated, so probably causes fluid sample can not be full of fluid sample chamber completely, and there will be suck off and on or time little volume of blood flow when large.In addition, in use, user is difficult to, by fluid sample aligned with channel entrance, especially those had defective vision and/or have hand to tremble the diabetic of phenomenon some sensor.In addition, in when sampling, blood sample also may scatter getting blood point skin surface around, and the fluid sample of the blood suction sensor that these are scattered is indoor is very difficult.
And fluid sample cannot enter into fluid sample chamber preferably, finally may cause actual testing result to depart from actual value, and then cause the successive treatment carrying out according to this testing result to occur mistake.The blood sugar of take examination bar is example, if the blood sugar test result detecting departs from actual value, follow-up insulin management dosage mistake just may occur, the situation that even jeopardizes patient's life.
Therefore, how improving the property easy to use of sensor, and guarantee that analyzed sample is full of fluid sample chamber completely, to guarantee the accuracy of testing result, is those skilled in the art's technical matterss urgently to be resolved hurrily.
Utility model content
In view of this, the utility model provides a kind of biology sensor, to solve biology sensor in prior art, exists fluid sample to enter the problem of fluid sample chamber difficulty.
For achieving the above object, the utility model provides following technical scheme:
A biology sensor, comprising:
Sensor body, one end of described sensor body is collection terminal, and the other end is for electrically contacting end, and described collection terminal is provided with the groove as fluid sample chamber, and the opening length of described groove is more than or equal to half of described collection terminal end face length;
Be positioned at the electrode of described sensor body inside, described electrode has two at least, one end of described electrode communicates with the inside of described groove, described in the other end is positioned at, electrically contacts end, is coated with for reacting with fluid sample and produces the chemical reagent that can survey electrochemical signals on described electrode.
Preferably, in above-mentioned biology sensor, described sensor body comprises:
Basic unit, described electrode is arranged at the upper surface of described basic unit;
Middle layer, the one end in described middle layer is provided with breach;
Upper strata, described basic unit, described middle layer and described upper strata be stack successively from below to up, an end part aligning on an end of described basic unit and described upper strata, and the described breach in described middle layer is clipped in the middle, using and form the described groove as described fluid sample chamber.
Preferably, in above-mentioned biology sensor, the width on described basic unit, described middle layer and described upper strata equates, described in being positioned at, described middle layer and described upper strata electrically contact the end part aligning of end, and, the length on described upper strata is less than the length of described basic unit, and the outermost end that described basic unit, described middle layer and described upper strata are positioned at described collection terminal is in alignment with each other.
Preferably, in above-mentioned biology sensor, the width on described basic unit, described middle layer and described upper strata equates, described in being positioned at, described middle layer and described upper strata electrically contact the end part aligning of end, and, the length on described upper strata is less than the length of described basic unit, and described basic unit and described upper strata are positioned at the outermost end alignment of described collection terminal, and exceeds the outermost end in described middle layer.
Preferably, in above-mentioned biology sensor, described breach be shaped as arc, square, rectangle, triangle or trapezoidal.
Preferably, in above-mentioned biology sensor, described basic unit is high polymer layer, and described electrode is the conductive coating that is coated in described basic unit upper surface;
Described middle layer is that described adhesive-layer has electrical insulation property for connecting the adhesive-layer on described basic unit and described upper strata;
Described upper strata is high polymer layer, and the part that the lower surface on described upper strata is corresponding with described groove location is coated with the coating of water wetted material.
Preferably, in above-mentioned biology sensor, described electrode comprises at least one contrast electrode and at least one working electrode.
From technique scheme, can find out, in order to facilitate fluid sample can enter into smoothly fluid sample chamber, in the utility model, the opening of the groove as fluid sample chamber is arranged widelyr, the length of the opening of groove is more than or equal to half of collection terminal end face length.Adopt above-mentioned design, the sample inlet of this super wide design (being the opening of groove), can be simultaneously as fluid sample injection port and air outlet, thereby without extra design air escape orifice again, can make the fluid sample chamber with super wide sample inlet be equivalent to thin layer kapillary, be conducive to improve the sampling process of fluid sample.When gathering, fluid sample because capillarity from a certain position of slot opening, to be inhaled into fluid sample indoor, air is overflowed from another position of slot opening, the opening of groove is simultaneously as fluid sample injection port and air outlet.As can be seen here, fluid sample can enter from any position of biology sensor front opening, if fluid sample enters in the middle of opening, air is overflowed from both sides; If fluid sample enters from a side of opening, air is overflowed from opposite side.In concrete application, above-mentioned biology sensor, owing to having adopted super wide sample inlet, so when blood is sucked to liquid sample chamber, can easily aim at micro-example, and easily suck a small amount of sample that skin surface scatters, eliminate the blockage problem of openend, and reduced the indoor sample of fluid sample while detecting full not exclusively, suck and discontinuous etc. may cause the inaccurate problem of test result.
Accompanying drawing explanation
In order to be illustrated more clearly in the utility model embodiment or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is only embodiment more of the present utility model, for those of ordinary skills, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 and Fig. 2 are respectively the perspective structure schematic diagram of the biology sensor that the utility model the first specific embodiment and the second specific embodiment provide;
The deployed configuration schematic diagram of the biology sensor being formed by trilaminate material that Fig. 3 provides for the utility model;
Fig. 4 and Fig. 5 are respectively the plan structure perspective diagram of the biology sensor that the utility model the first specific embodiment and the second specific embodiment provide;
The plan structure schematic diagram of the basic unit of the biology sensor that Fig. 6 provides for the utility model;
The plan structure comparison diagram in the middle layer of the biology sensor that Fig. 7 provides for the utility model the first specific embodiment and the second specific embodiment;
The upper strata plan structure schematic diagram of the biology sensor that Fig. 8 provides for the utility model;
The side-looking structural representation of the sensor body that Fig. 9 provides for the utility model the first specific embodiment;
The side-looking structural representation of the sensor body that Figure 10 provides for the utility model the second specific embodiment;
Two kinds of work schematic diagram of the biology sensor that Figure 11 and Figure 12 provide for the utility model the first specific embodiment;
Three kinds of work schematic diagram of the biology sensor that Figure 13, Figure 14 and Figure 15 provide for the utility model the second specific embodiment.
Wherein, 10 for electrically contacting end, and 20 is collection terminal, 30 is groove, and 91 is lateral access, and 100 is sensor body, 200Wei basic unit, 300 is middle layer, and 300a is the first middle layer, and 300b is the second middle layer, 400 is upper strata, 12 is contrast electrode, and 11 is the first working electrode, and 13 is the second working electrode.
Embodiment
The utility model discloses a kind of biology sensor, to solve biology sensor in prior art, exist fluid sample to enter the problem of fluid sample chamber difficulty.
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is clearly and completely described, obviously, described embodiment is only the utility model part embodiment, rather than whole embodiment.Embodiment based in the utility model, those of ordinary skills are not making the every other embodiment obtaining under creative work prerequisite, all belong to the scope of the utility model protection.
Refer to the perspective structure schematic diagram of the biology sensor that the utility model the first specific embodiment shown in Fig. 1 provides.
This biology sensor comprises sensor body 100 and is positioned at the electrode of sensor body 100 inside.Wherein, sensor body 100 is as the carrier of biology sensor, one end is collection terminal 20, the other end is for electrically contacting end 10, collection terminal 20 is provided with the groove 30 as fluid sample chamber, and its Main Function is to collect and receiving fluids sample, to carry out fluid sample test, wherein, the opening length of groove 30 is more than or equal to half of collection terminal 20 end face length; In sensor body 100, be at least provided with two electrodes (comprising working electrode and contrast electrode), one end of each electrode communicates with groove 30 inside on collection terminal 20 respectively, the other end of electrode is positioned at and electrically contacts end 10, electrically contact end 10 and insert instrument when measuring, on electrode, be coated with for reacting with fluid sample and produce the chemical reagent that can survey electrochemical signals.
From technique scheme, can find out, in order to facilitate fluid sample can enter into smoothly fluid sample chamber, in the utility model, the opening of the groove 30 as fluid sample chamber is arranged widelyr, as shown in fig. 1, the length of the opening of groove 30 is more than or equal to half of collection terminal 20 end face length.Adopt above-mentioned design, the sample inlet of this super wide design (being the opening of groove 30), can be simultaneously as fluid sample injection port and air outlet, thereby without extra design air escape orifice again, can make the fluid sample chamber with super wide sample inlet be equivalent to thin layer kapillary, be conducive to improve the sampling process of fluid sample.When gathering, fluid sample because capillarity from a certain position of groove 30 openings, to be inhaled into fluid sample indoor, air is overflowed from another position of groove 30 openings, the opening of groove 30 is simultaneously as fluid sample injection port and air outlet.Refer to two kinds of work schematic diagram of the biology sensor that the utility model the first specific embodiment shown in Figure 11 and Figure 12 provides, this schematic view illustrating blood sample how to enter groove 30 and the air of the discharging groove 30 of how overflowing, wherein, filled arrows indication blood sample approach axis, hollow arrow indication air effusion direction.As can be seen here, fluid sample can enter from any position of biology sensor front opening, if fluid sample enters in the middle of opening, air is from both sides effusions (Figure 11); If fluid sample enters from a side of opening, air is from opposite side effusion (Figure 12).
In concrete application, above-mentioned biology sensor, owing to having adopted super wide sample inlet, so when blood is sucked to liquid sample chamber, can easily aim at micro-example, and easily suck a small amount of sample that skin surface scatters, eliminate the blockage problem of openend, and reduced the indoor sample of fluid sample while detecting full not exclusively, suck and discontinuous etc. may cause the inaccurate problem of test result.
Accompanying drawing about the first specific embodiment refers to Fig. 3, Fig. 4, Fig. 6-Fig. 9, the deployed configuration schematic diagram that Fig. 3 is the biology sensor that is comprised of trilaminate material, Fig. 4 is the plan structure perspective diagram of this biology sensor, Fig. 9 is the side-looking structural representation of sensor body 100, the plan structure schematic diagram of Tu6Wei basic unit, in Fig. 7, left side figure is the plan structure schematic diagram in the middle layer of the first specific embodiment, the plan structure schematic diagram that Fig. 8 is upper strata.
In above-mentioned the first specific embodiment, the sensor body 100 of biology sensor is comprised of trilaminate material, and trilaminate material is specially from below to up basic unit 200, the 300He upper strata, middle layer 400 of stack successively, as shown in Figure 3.Wherein, end of basic unit 200 and an end part aligning on upper strata 400, and the breach of 300 ends, middle layer is clipped in the middle, using and form as the groove 30(of fluid sample chamber as shown in Figure 1).Particularly, basic unit 200 is high polymer layer, its upper surface is provided with conducting membrane material, the conductive layer consisting of conducting membrane material is divided into three conductive regions, three respectively corresponding three electrodes of conductive region, centre is contrast electrode 12, and both sides are respectively the first working electrode 11 and the second working electrode 13(as shown in Figure 3); Middle layer 300, for for connecting the layers of two-sided on basic unit 200 and upper strata 400, has electrical insulation property; Upper strata 400 is high polymer layer (for example plastic sheeting), and the region that its lower surface is corresponding with breach is coated with the coating of water wetted material, the capillarity when promoting to sample.When concrete production, can be also the coating that 400 whole lower surface all scribbles water wetted material on upper strata, and then bonding with middle layer 300.Trilaminate material is so fitted, to form biology sensor as shown in Figure 1.
Particularly, as shown in Fig. 1, Fig. 4 and Fig. 9, the width on basic unit 200,300He upper strata, middle layer 400 equates, the outermost end that basic unit 200,300He upper strata, middle layer 400 are positioned at collection terminal 20 is in alignment with each other, middle layer 300 is positioned at and electrically contacts end 10 end and upper strata 400 and be positioned at the end that electrically contacts end 10 and be in alignment with each other, and the length on upper strata 400 is less than the length of basic unit 200, thereby make the electrode electrically contacting on end 10 of basic unit 200 be exposed to outside, so that insert instrument, test.
Particularly, the shape of the breach of 300 ends, middle layer can be set to arc or semicircle, and when this shape refers to 200 laminating of middle layer 300He basic unit, breach projection is in the shape of the upper surface of basic unit 200.For example, the breach of 300 ends, middle layer is semicircle, and its diameter minimum is 1mm, guarantees that this diameter is more than or equal to the width of the collection terminal of sensor body 100.Preferred diameter dimension is the width that is slightly less than the collection terminal of sensor body 100, and preferred diameter is 2-20mm.For example, in specific embodiment, the width of the collection terminal of sensor body 100 is 6mm, and the preferred diameter of semicircle breach is 5.2mm left and right.So, blood sample can enter from arbitrary position of sensor body upper groove 30 openings (injection port that 5.2mm is wide) groove 30 inside (being fluid sample chamber).In specific embodiment, the thickness in middle layer 300 can be 0.01-0.5mm, is preferably 0.05-0.15mm, and for example preferred thickness is 0.1mm.Clearly, the thickness of middle layer 300 end breach and size have determined the capacity of fluid sample chamber, for example, are about 1 microlitre or less.
But those skilled in the art easily know, the utility model is not limited to this.In above-mentioned specific embodiment, about the molding mode of sensor body 100, can there is multiple implementation, sensor body 100 can be combined by sandwich construction, can be also integrated formed structure; And, about shape, relative position and the size of electrode, also can there is multiple design proposal, three electrodes shown in Fig. 3 be arranged in parallel at the upper surface of basic unit 200, and this is only preferred version; And the shape of the breach of 300 ends, middle layer can also be square, rectangle, triangle or trapezoidal.
In addition, the utility model also can have plurality of optional scheme about the design of concrete material:
For example, the macromolecule polymer material as basic unit 200 includes but not limited to tygon, polypropylene, polystyrene, Polyvinylchloride, teflon, polycarbonate, polyester, polystyrene diformate, polyimide and composition thereof.
For example, as the conductive coating material of electrode, can be any one in carbon, various metals or metal oxide.Conductive coating can make by the whole bag of tricks of knowing in industry, includes but not limited to printing (as serigraphy), coating (as reverse roll coating), vapour deposition, sputter, chemogenic deposit, electrochemical deposition etc.Conductive coating can be to cover on whole piece insulating material, if need to make several electrodes, can obtain by the conductive channel of etching or scribing requirement.Etching process can complete by chemical method, on conductive layer with mechanical method groove, or complete with being laser-cut into independently conductive channel method.Conductive coating material can be but be not limited to various material with carbon elements, or as the various metals such as gold, platinum, palladium, iridium, rhodium, ruthenium, or as various metal oxides such as indium oxide and tin oxide, and their composition.
For example, in basic unit 200, can hold chemical reagent, chemical reagent covers on electrode, also can optionally cover on the first working electrode 11 and contrast electrode 12.In a certain specific embodiment, on the second working electrode 13, perhaps there is no the reagent that can react with determinand, so, the second working electrode 33 can be used as blank electrode, the signal producing on blank electrode is the background signal of counter sample, the signal deduction that this signal is produced from the first working electrode 31, obtains the signal of determinand, can eliminate background interference since so.If the biology sensor that the utility model provides is for the mensuration of blood sugar, the signal producing on blank electrode may be that in blood sample, various interfering materials produce, and this interfering material can be the ascorbic acid in blood sample, Paracetamol, uric acid, cholerythrin etc.In addition, the second working electrode 33 also has other purposes, according to the size of its signal and other features, judges whether aforementioned grooves 30 is full of by blood sample, with the accuracy that guarantees to measure.
And in specific embodiment, chemical reagent can be enzyme, antibody, antigen, complexometric reagent, substrate or its combination.Select suitable reagent and detected analyte response, to determine the concentration of analyte in fluid sample.In a certain specific embodiment, chemical reagent comprises enzyme conventionally, as glucose oxidase, glucose dehydrogenase, cholesterol oxidase, creatinine amidin hydrolytic enzyme, Lactate Oxidase, peroxidase, uricase, xanthine oxidase etc., react with analyte and electron accepter (as ferricyanide salt), generation can be by the material of Electrochemical Detection.Such as sensor is used for analyzing the concentration of glucose, the enzyme using so can be glucose oxidase or glucose dehydrogenase; If substance to be measured is uric acid, the enzyme using so can be uricase.Should be noted that, in some cases, in order to produce the electrochemical signals that can survey, the enzyme that sensor uses may be incessantly a kind of, such as, for measuring the sensor of cholesterol, used and comprised cholesterol esterase, the potpourri of cholesterol oxidase and peroxidase.For making sensor, effectively work, in chemical reagent, also can comprise polymkeric substance, enzyme, surfactant, electron mediator (electron accepter or electronq donor), damping fluid, the potpourri of stabilizing agent and bonding agent, preferred electron mediator is the redox chemistry material in oxidation state or reduction-state, can include but not limited to various metals or precious metal chemical complex, as the potassium ferricyanide, potassium ferrocyanide, Cobalt Phthalocyanine, various ferrocene and various organic oxidation reducing medium, as methylene blue, methylenum careuleum is green, 7, 7, 8, 8-four cyano bismethane, tetrathiafulvalene, toluidine blue, meldola blue, n-toluphenazine, Methylsulfate, phenylenediamine, 3, 3', 5, 5'-tetramethyl benzidine, pyrogaelol, benzoquinones and phenanthrolene-5, 6,-diketone etc.If the enzyme that sensor uses is glucose oxidase or glucose dehydrogenase, can, with the potassium ferricyanide as redox electron mediator, if the enzyme that sensor uses comprises peroxidase, can use so potassium ferrocyanide as redox electron mediator.
For example, in specific embodiment, middle layer 300, except adopting double faced adhesive tape, can also be made by plastic insulation material, and its upper and lower surface scribbles glue or tackifier, is respectively used to fix with basic unit 200 and upper strata 400.In addition, on market, obtainable two-sided pressure-sensitive adhesive tape can be used as middle layer 300.
Therefore, the utility model is to above-mentioned specific design scheme and be not specifically limited.
In addition, the utility model also provides the second specific embodiment, accompanying drawing for the second specific embodiment refers to Fig. 2, Fig. 5 and Figure 10, Fig. 2 is the perspective structure schematic diagram of this biology sensor, the plan structure perspective diagram of this biology sensor of Fig. 5, the side-looking structural representation that Figure 10 is this sensor body.The second specific embodiment and the first specific embodiment basic structure are similar, its key distinction is: 1. middle layer 300 is shorter, as shown in Figure 7, the plan structure comparison diagram in the middle layer of the biology sensor that Fig. 7 provides for the utility model the first specific embodiment and the second specific embodiment, if the middle layer of the biology sensor in the first specific embodiment is the first middle layer 300a, the middle layer of the biology sensor in the second specific embodiment is the second middle layer 300b, visible, the length of the first middle layer 300a is greater than the length of the second middle layer 300b; When 2. trilaminate material is fitted, basic unit 200 and upper strata 400 are positioned at the outermost end alignment of collection terminal 20, and exceed the outermost end in middle layer 300, as shown in figure 10.
Particularly, the second middle layer 300b is the replacement scheme of the first middle layer 300a, its width is the same with basic unit 200, and length is less than basic unit 200, to 10 expose the electrode (the first working electrode 11, contrast electrode 12 and the second working electrode 13) that is positioned at basic unit's 200 upper surfaces electrically contacting end.Notice that the length of 300b is slightly smaller than the length on upper strata 400.
Visible, in the biology sensor that the second specific embodiment provides, the width of upper strata 400, middle layer 300b and basic unit 200 equates, and fit together successively from top to bottom, and the groove 30(forming at collection terminal 20 is shown in Fig. 2) opening is larger, and formation lateral access 91.By the design of this uniqueness, make the collection terminal 20 of sensor body 100 form a sampling entrance (seeing Fig. 2) that surpasses 180 degree, wider than the opening of the groove 30 in the first specific embodiment, and have larger angle.Therefore, blood sample not only can enter fluid sample chamber (seeing Figure 13 and Figure 14) at arbitrary position of the open front of groove 30, can also in the passage 91 of groove 30 opening both sides, enter into fluid sample chamber (seeing Figure 15).
Three kinds of work schematic diagram of the biology sensor that Figure 13, Figure 14 and Figure 15 provide for the utility model the second specific embodiment, the groove 30 that illustrated how blood sample enters the groove 30 of the biology sensor that the utility model the second specific embodiment provides and how the air of discharging overflows, filled arrows and hollow arrow are indicated respectively blood sample approach axis and air effusion direction.As can be seen here, fluid sample can enter from any position of biology sensor front opening.If fluid sample enters from centre, air is from both sides effusions (Figure 13); If fluid sample enters from a side of front end, air is from the passage 91 of opposite side and both sides overflow (Figure 14); In addition,, if fluid sample enters from a side 91, air is from front end and 91 effusions (Figure 15) of opposite side passage.Be not difficult to find out, the biology sensor that the second specific embodiment provides is compared with the biology sensor that the first specific embodiment provides, and has the injection port of wider more wide-angle.
Although the above structure of biology sensor and the description of making that the utility model is provided is for single sensor, this design and the material using can be used for first making each a sheet of monolayer material equally, then prepare a plurality of biology sensors.This can be by first making (comparing with each layer of single-sensor) relative large base material, middle layer material and upper layer of material, through series of process processes such as processing, laminating and shearings, thereby is embodied as the batch production of this economy.
Above a kind of biology sensor provided by the utility model is described in detail, applied specific case herein principle of the present utility model and embodiment are set forth, the explanation of above embodiment is just for helping to understand method of the present utility model and core concept thereof; , for one of ordinary skill in the art, according to thought of the present utility model, all will change in specific embodiments and applications, in sum, this description should not be construed as restriction of the present utility model meanwhile.
In this instructions, each embodiment adopts the mode of going forward one by one to describe, and each embodiment stresses is the difference with other embodiment, between each embodiment identical similar part mutually referring to.
It should be noted that, in this article, such as " being greater than " or " surpassing " or " higher than " or " being less than " or " lower than " etc. relationship description, all can be understood as " be greater than and be not equal to " or " be less than and be not equal to ", also can be understood as " being more than or equal to " or " being less than or equal to ", and not necessarily require or imply a kind of situation restriction or intrinsic that is necessary for.
In addition, in this article, relational terms such as " first " and " second " etc. is only used for an entity or operation to separate with another entity or operational zone, and not necessarily requires or imply and between these entities or operation, have the relation of any this reality or sequentially.And, in this article, term " comprises ", " comprising " or its any other variant are intended to contain comprising of nonexcludability, thereby the process, method, article or the equipment that make to comprise a series of key elements not only comprise those key elements, but also comprise other key elements of clearly not listing, or be also included as the intrinsic key element of this process, method, article or equipment.The in the situation that of more restrictions not, the key element being limited by statement " comprising ... ", and be not precluded within process, method, article or the equipment that comprises described key element and also have other identical element.
It should be noted that, the above is only a part of preferred embodiment of technical solutions of the utility model, make those skilled in the art can fully understand or realize the utility model, rather than whole embodiment, General Principle as defined herein can, in the situation that not departing from spirit or scope of the present utility model, realize in other embodiments.Therefore; based on above embodiment; for those skilled in the art; do not depart from the utility model principle, do not making under creative work prerequisite, can also make multiple apparent modification and retouching; the every other embodiment obtaining by these modifications and retouching; can be applied to technical solutions of the utility model, these do not affect realization of the present utility model, all should belong to protection domain of the present utility model.Therefore, the utility model will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (7)
1. a biology sensor, is characterized in that, comprising:
Sensor body (100), one end of described sensor body (100) is collection terminal (20), the other end is for electrically contacting end (10), described collection terminal (20) is provided with the groove (30) as fluid sample chamber, and the opening length of described groove (30) is more than or equal to half of described collection terminal (20) end face length;
Be positioned at the inner electrode of described sensor body (100), described electrode has two at least, one end of described electrode communicates with the inside of described groove (30), described in the other end is positioned at, electrically contact end (10), on described electrode, be coated with for reacting with fluid sample and produce the chemical reagent that can survey electrochemical signals.
2. biology sensor according to claim 1, is characterized in that, described sensor body (100) comprising:
Basic unit (200), described electrode is arranged at the upper surface of described basic unit (200);
Middle layer (300), the one end of described middle layer (300) is provided with breach;
Upper strata (400), described basic unit (200), described middle layer (300) and described upper strata (400) are stack successively from below to up, an end of described basic unit (200) and an end part aligning of described upper strata (400), and the described breach of described middle layer (300) is clipped in the middle, usings and form the described groove (30) as described fluid sample chamber.
3. biology sensor according to claim 2, it is characterized in that, the width of described basic unit (200), described middle layer (300) and described upper strata (400) equates, described in being positioned at, described middle layer (300) and described upper strata (400) electrically contact the end part aligning of end (10), and, the length on described upper strata (400) is less than the length of described basic unit (200), and the outermost end that described basic unit (200), described middle layer (300) and described upper strata (400) are positioned at described collection terminal (20) is in alignment with each other.
4. biology sensor according to claim 2, it is characterized in that, the width of described basic unit (200), described middle layer (300) and described upper strata (400) equates, described in being positioned at, described middle layer (300) and described upper strata (400) electrically contact the end part aligning of end (10), and, the length on described upper strata (400) is less than the length of described basic unit (200), described basic unit (200) and described upper strata (400) are positioned at the outermost end alignment of described collection terminal (20), and exceed the outermost end of described middle layer (300).
5. biology sensor according to claim 2, is characterized in that, described breach be shaped as arc, square, rectangle, triangle or trapezoidal.
6. according to the biology sensor described in claim 2-5 any one, it is characterized in that, described basic unit (200) is high polymer layer, and described electrode is for being coated in the conductive coating of described basic unit (200) upper surface;
Described middle layer (300) is that described adhesive-layer has electrical insulation property for connecting the adhesive-layer of described basic unit (200) and described upper strata (400);
Described upper strata (400) is high polymer layer, and the part that the lower surface of described upper strata (400) is corresponding with described groove (30) position is coated with the coating of water wetted material.
7. biology sensor according to claim 1, is characterized in that, described electrode comprises at least one contrast electrode and at least one working electrode.
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