CN203479692U - Slit-waveguide-based glucose detection device - Google Patents
Slit-waveguide-based glucose detection device Download PDFInfo
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- CN203479692U CN203479692U CN201320489010.7U CN201320489010U CN203479692U CN 203479692 U CN203479692 U CN 203479692U CN 201320489010 U CN201320489010 U CN 201320489010U CN 203479692 U CN203479692 U CN 203479692U
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- waveguide
- straight line
- circular arc
- blood sugar
- refractive index
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- 238000001514 detection method Methods 0.000 title claims abstract description 23
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract description 5
- 239000008103 glucose Substances 0.000 title abstract description 5
- 239000008280 blood Substances 0.000 claims abstract description 51
- 210000004369 blood Anatomy 0.000 claims abstract description 51
- 239000000463 material Substances 0.000 claims abstract description 22
- 238000006243 chemical reaction Methods 0.000 claims description 10
- 230000005540 biological transmission Effects 0.000 claims description 7
- 239000002210 silicon-based material Substances 0.000 claims description 3
- 238000012360 testing method Methods 0.000 description 16
- 238000005516 engineering process Methods 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 4
- 229910052710 silicon Inorganic materials 0.000 description 4
- 239000010703 silicon Substances 0.000 description 4
- 229910001218 Gallium arsenide Inorganic materials 0.000 description 2
- 229910052581 Si3N4 Inorganic materials 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910052681 coesite Inorganic materials 0.000 description 1
- 229910052906 cristobalite Inorganic materials 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011551 heat transfer agent Substances 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229910052682 stishovite Inorganic materials 0.000 description 1
- 229910052905 tridymite Inorganic materials 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
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- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model discloses a slit-waveguide-based glucose detection device. The slit-waveguide-based glucose detection device comprises a direct waveguide and a microring waveguide, wherein the area between the direct waveguide and the microring waveguide is an area defined by a straight line and a circular arc; the shortest distance between the straight line and the circular arc is positioned on the straight line which passes through the circle center of the circular arc and is perpendicular to the straight line; the shortest distance between the straight line and the circular arc is 50 to 80nm; the annular slit area is a detection channel for a blood sample to be detected to flow; the refractive index of a material of the direct waveguide is higher than that of the blood sample. The utility model provides the slit-waveguide-based glucose detection device; the requirements on high detection efficiency and high response speed are met; the structure is simplified, the size is reduced and the cost is reduced.
Description
Technical field
The utility model relates to blood sugar test field, especially a kind of blood sugar detection apparatus.
Background technology
In existing blood sugar test technology, conventional blood sugar test is for there being wound to detect, and medical treatment is medical slow, and efficiency is low, and intellectuality is not high.
Someone proposes to utilize microwave technology to realize blood sugar test, and for example the patent No. is 200710200028.X, and denomination of invention is: the Chinese invention patent application of non-wound rapid blood sugar detector.Utilize microwave technology to realize blood sugar test, the rapidity of detection is better, the technological deficiency of existence: the complex structure of whole checkout equipment, size are large, response is slower, and cost is higher.
2004, the Michal Lipson of Cornell Univ USA professor seminar has proposed concept (the Almeida VR of narrow slit wave-guide first, Xu Q, Barrions CA et al..Guiding and confining light in void nanostructure[J] .Opt.Lett., 2004,29 (11): 1209～1211; Almeida VR, Xu Q, Barrions CA, Deng, the conduction of light and restriction in nanostructured space, optics letter, 2004,29 (11): 1209～1211), and by the nanometer scale optical waveguide structure that theoretical and experiment have confirmed to have high index-contrast, light field can be limited in the slit of low-refraction and transmit.Waveguiding structure comprises that the high index waveguide core (typical case as Si material) of both sides and middle low-refraction slit dielectric area are (such as air, fluid or SiO2 etc.), slit dielectric area width is generally less than 100nm, this waveguiding structure has demonstrated the characteristic different from traditional optical waveguide, can be by luminous energy flow restriction in low-refraction slit.Based on this characteristic, can design the various novel optical functional devices that are applied to optical communication and light sensing, thereby be subject to association area researcher's extensive concern.
Summary of the invention
In order to overcome the complex structure of existing blood sugar test technology, the deficiency that size is large, cost is higher, the utility model provides a kind of and is meeting high detection efficiency and fast in response, simplified structure, reduced in size, the blood sugar detection apparatus based on narrow slit wave-guide that reduces costs.
The utility model solves the technical scheme that its technical matters adopts:
A kind of blood sugar detection apparatus based on narrow slit wave-guide, comprise that a straight wave guide and a micro-ring waveguide form, narrow annular channel region between described straight wave guide and micro-ring waveguide is straight line and a region that circular arc surrounds, between straight line and circular arc, bee-line is positioned at by the straight line vertical with straight line of the circular arc center of circle, the bee-line of setting between straight line and circular arc is 50～80nm, the sense channel of described narrow annular channel region for flowing through for blood sample to be detected, the refractive index of the refractive index ratio blood sample of described straight wave guide material is high.
Further, described blood sugar detection apparatus also comprises and spreads out of part, the described part that spreads out of comprises transmission module in bus waveguide, photoelectric conversion module and an information, the light field signal output part of described narrow annular channel waveguide is connected with described bus waveguide, described bus waveguide is connected with described photoelectric conversion module, and described photoelectric conversion module is connected with transmission module in described information.
Further, the refractive index of narrow annular channel waveguide is high more than 2.0 described in the refractive index ratio of described straight wave guide material, as long as the refractive index of narrow annular channel waveguide is high described in the refractive index ratio of described straight wave guide material, such as high 1.0 other numerical value such as grade; It is larger that refractive index differs, and is more conducive to the constraint to light, and therefore, it is very little that the size of waveguide can be made, and integrated level is higher.
Described straight wave guide material is silicon materials, and this scheme is a preferred case, and the refractive index of silicon is 3.48, and supplying the refractive index of blood sample to be detected is that 1.46(can be also other refractive indexes), the refringence of wave guide zone and slit area is 2.02; Certainly, described straight wave guide material also can be selected other materials, such as silicon nitride material, GaAs material etc.
Technical conceive of the present utility model is: detected object is the blood sample that Wicresoft obtains, Detection of content is blood sugar test, the basic sensing unit of blood sugar test is a straight wave guide and a narrow slit wave-guide that micro-ring waveguide forms, the refractive index of blood sample can change along with the variation of blood sugar concentration, and the change in optical path length of the variation of refractive index can cause the slit waveguide structure of light by between straight wave guide and micro-ring time, and and then change the resonance wavelength of micro-ring waveguide, by detecting the variation of resonance wavelength, can detect the blood glucose concentration value of blood sample.
The beneficial effects of the utility model are mainly manifested in: 1, in narrow slit wave-guide, light field changes obviously and rapidly, has conveniently, efficiently feature; 2, the utility model is microchip structure, has the feature of integrated level Gao, Wicresoft, safety.
Accompanying drawing explanation
Fig. 1-1st, the blood sugar detection apparatus schematic diagram based on narrow slit wave-guide, wherein, straight waveguide: straight wave guide, slot: slit, micro-ring: micro-ring, Bus: bus waveguide.
Fig. 1-2 is test section structural representation.
Embodiment
Below in conjunction with accompanying drawing, the utility model is further described.
With reference to Fig. 1, a kind of blood sugar detection apparatus based on narrow slit wave-guide, comprise that a straight wave guide and a micro-ring waveguide form, narrow annular channel region between described straight wave guide and micro-ring waveguide is straight line and a region that circular arc surrounds, between straight line and circular arc, bee-line is positioned at by the straight line vertical with straight line of the circular arc center of circle, the bee-line of setting between straight line and circular arc is 50～80nm, the sense channel of described narrow annular channel region for flowing through for blood sample to be detected, the refractive index of the refractive index ratio blood sample of described straight wave guide material is high.
Further, described blood sugar detection apparatus also comprises and spreads out of part, the described part that spreads out of comprises transmission module in bus waveguide, photoelectric conversion module and an information, the light field signal output part of described narrow annular channel waveguide is connected with described bus waveguide, described bus waveguide is connected with described photoelectric conversion module, and described photoelectric conversion module is connected with transmission module in described information.
Further, described in the refractive index ratio of described straight wave guide material, the refractive index of narrow annular channel waveguide is high more than 2.0.As long as described in the refractive index ratio of described straight wave guide material, the refractive index of narrow annular channel waveguide is high, such as high 1.0 other numerical value such as grade; It is larger that refractive index differs, and is more conducive to the constraint to light, and therefore, it is very little that the size of waveguide can be made, and integrated level is higher.
Described straight wave guide material is silicon materials, and this scheme is a preferred case, and the refractive index of silicon is 3.48, and supplying the refractive index of blood sample to be detected is that 1.46(can be also other refractive indexes), the refringence of wave guide zone and slit area is 2.02; Certainly, described straight wave guide material also can be selected other materials, such as silicon nitride material, GaAs material etc.
The test section of the present embodiment is blood sugar test assembly.Blood sugar test assembly consists of a straight wave guide and a micro-ring waveguide, slit areas between straight wave guide and micro-ring is straight line and a region that circular arc surrounds, between straight line and circular arc, bee-line is positioned at by the straight line vertical with straight line of the circular arc center of circle, and the bee-line of setting between straight line and circular arc is 50～80nm.Test section structure as shown in Figure 1-2.The physical quantity of test section sensing is the variation of resonance wavelength in micro-ring waveguide.
The blood sugar detection apparatus based on narrow slit wave-guide of the present embodiment is that narrow annular channel waveguide and bus waveguide form.Illustrate: all straight wave guide region material are silicon, the refractive index of confession blood sample to be detected is 1.46, and the refractive index of silicon and confession blood sample to be detected is respectively 3.48 and 1.46, and wave guide zone and slit area refringence are 2.02.Because the refringence in wave guide zone and narrow annular channel district is very large, be conducive to the constraint to light, so waveguide dimensions can make very littlely, integrated level is higher.Concrete embodiment is as follows:
First, need utilize orthoglycemic blood sample to demarcate test, slit areas minimum dimension is 50nm, passes through normal blood in slit, and after logical light, tests the resonance wavelength of micro-ring as demarcating wavelength in high index of refraction straight wave guide.In slit, pass into afterwards blood sample to be checked, and the resonance wavelength of observing micro-ring after logical light in high index of refraction straight wave guide, if resonance wavelength is identical with demarcation wavelength, show that blood sample blood sugar concentration to be checked is normal, if resonance wavelength is different from demarcation wavelength, show that blood sample blood sugar concentration to be checked is abnormal, if resonance wavelength reduces to show that blood sugar concentration is higher, if resonance wavelength increases, show that blood sugar concentration is on the low side.
The signal of bus waveguide output is converted into electric signal by photoelectric conversion module, then by transmission module in information, the heat transfer agent that converts electric signal to is sealed, and by PC, being uploaded to internet ，Yu special medical mechanism, to carry out snap information mutual.Between special medical mechanism, use optical fiber to realize large band data communication.
Claims (4)
1. the blood sugar detection apparatus based on narrow slit wave-guide, it is characterized in that: comprise that a straight wave guide and a micro-ring waveguide form, narrow annular channel region between described straight wave guide and micro-ring waveguide is straight line and a region that circular arc surrounds, between straight line and circular arc, bee-line is positioned at by the straight line vertical with straight line of the circular arc center of circle, the bee-line of setting between straight line and circular arc is 50～80nm, the sense channel of described narrow annular channel region for flowing through for blood sample to be detected, the refractive index of the refractive index ratio blood sample of straight wave guide material is high.
2. the blood sugar detection apparatus based on narrow slit wave-guide as claimed in claim 1, it is characterized in that: described blood sugar detection apparatus also comprises and spreads out of part, the described part that spreads out of comprises transmission module in bus waveguide, photoelectric conversion module and an information, the light field signal output part in described narrow annular channel region is connected with described bus waveguide, described bus waveguide is connected with described photoelectric conversion module, and described photoelectric conversion module is connected with transmission module in described information.
3. the blood sugar detection apparatus based on narrow slit wave-guide as claimed in claim 1 or 2, is characterized in that: described in the refractive index ratio of described straight wave guide material, the refractive index in narrow annular channel region is high more than 2.0.
4. the blood sugar detection apparatus based on narrow slit wave-guide as claimed in claim 1 or 2, is characterized in that: described straight wave guide material is silicon materials.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201320489010.7U CN203479692U (en) | 2013-08-12 | 2013-08-12 | Slit-waveguide-based glucose detection device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201320489010.7U CN203479692U (en) | 2013-08-12 | 2013-08-12 | Slit-waveguide-based glucose detection device |
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| CN201320489010.7U Expired - Fee Related CN203479692U (en) | 2013-08-12 | 2013-08-12 | Slit-waveguide-based glucose detection device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103471997A (en) * | 2013-08-12 | 2013-12-25 | 浙江工业大学 | Slot waveguide based blood sugar detection apparatus |
| CN107941735A (en) * | 2017-11-10 | 2018-04-20 | 吉林大学 | Infrared double aperture slit waveguide microcavity spectroscopic gas sensor and its application method in one kind |
-
2013
- 2013-08-12 CN CN201320489010.7U patent/CN203479692U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103471997A (en) * | 2013-08-12 | 2013-12-25 | 浙江工业大学 | Slot waveguide based blood sugar detection apparatus |
| CN107941735A (en) * | 2017-11-10 | 2018-04-20 | 吉林大学 | Infrared double aperture slit waveguide microcavity spectroscopic gas sensor and its application method in one kind |
| CN107941735B (en) * | 2017-11-10 | 2020-07-14 | 吉林大学 | Mid-infrared double-slit waveguide microcavity spectrum gas sensor and use method thereof |
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