CN203425379U - Real-time electro-cardio stimulating and monitoring wireless module and system - Google Patents

Real-time electro-cardio stimulating and monitoring wireless module and system Download PDF

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Publication number
CN203425379U
CN203425379U CN201320198714.9U CN201320198714U CN203425379U CN 203425379 U CN203425379 U CN 203425379U CN 201320198714 U CN201320198714 U CN 201320198714U CN 203425379 U CN203425379 U CN 203425379U
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low
power consumption
cardio
electro
stimulating
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CN201320198714.9U
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李毅刚
张文赞
罗章源
涂权
周志文
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JIESHENG BIOTECHNOLOGY (SHANGHAI) CO Ltd
XinHua Hospital Affiliated To Shanghai JiaoTong University School of Medicine
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JIESHENG BIOTECHNOLOGY (SHANGHAI) CO Ltd
XinHua Hospital Affiliated To Shanghai JiaoTong University School of Medicine
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Abstract

The utility model relates to a real-time electro-cardio stimulating and monitoring wireless module and a real-time electro-cardio stimulating and monitoring wireless system. The real-time electro-cardio stimulating and monitoring wireless module is composed of an electronic component box, a stimulating electrode and a monitoring electrode; a lithium thionyl chloride battery, a low-power consumption microprocessor, a bioelectricity collector, a constant current source stimulator and an antenna are arranged inside the electric component box. The monitoring electrode is connected with the bioelectricity collector, and acquires electro-cardio data and outputs the electro-cardio data to the low-power consumption microprocessor; the low-power consumption microprocessor transmits out the electro-cardio data through the antenna; the antenna receives stimulation control instructions and transmits the stimulation control instructions to the low-power consumption microprocessor; The low-power consumption microprocessor controls the constant current source stimulator; and the constant current source stimulator is connected with the stimulating electrode and outputs stimulating signals. The module can be implanted into human and animal organic bodies, as a result, real-time electro-cardio monitoring can be performed, and an electro-cardio stimulating circuit of the module can be also utilized to perform electro-cardio stimulation on the human and animal organic bodies, and therefore, the module can be utilized to induct and terminate ventricular tachycardia or other electro-cardio functions.

Description

A kind of heart real time stimulates, guards wireless module and system
Technical field
This utility model relates to medical instruments field, and being specifically related to a kind of heart real time stimulates, guards wireless module and system.
Background technology
Current cardiac stimulation, the prior art of monitoring aspect is as follows:
1. external remote electrocardiogram monitor: Holter system can continuous monitoring 24-72 hour the electrocardiogram of longer time even.Yet Holter system is retrospective ecg information analysis mostly mostly at present, seldom there is real time monitoring function, writing time is short, be not easy to record Main adverse cardiovascular event, also because need connection electrode low etc. to patient body discomfort and compliance, be therefore difficult to be applied to remote ecg monitoring and diagnosis.
Utilize even the Internet of phone or GPRS (GPRS (general packet radio service)), event-triggered electro-cardiograph can be interrupted or continuously by ecg information long-distance transmissions to hospital or doctor's office, thereby be conducive to diagnosis and the treatment of disease.Event-triggered electro-cardiograph is according to ARR identification setting, automatically to trigger ecg information transmission a bit, and also having is to need patient's Self-operating device and carry out electrocardio transmission.Although these equipment have overcome the deficiency of Holter system to a certain extent, the transmission of ecg information that can be long-time and real-time, also has suitable weak point: can not the preictal electrocardiogram of recording events; Because carrying, be inconvenient to affect patient's life; Because lead, connection waits complicated operation, and patient does not often wear equipment on request, and arrhythmia may stop when having malaise symptoms just to wear upper equipment; As necessarily required patient in waking state for manual activation.
No matter be Holter system or real-time or non real-time electro-cardiograph, external remote electrocardiogram monitor all has that patient compliance is poor, electrode easily comes off, complicated operation, be vulnerable to disturb, the factor such as impact life and often can only record electrocardiogram few in number.More very, these equipment there is no any treatment function.
2. implanted remote ecg monitoring: the monitoring of implanted remote ecg is that electrocardio detected electrons equipment is directly implanted in the body, externally join a receptor, electrocardiosignal is sent to medical centre, do not exist electrode to come off and the factor such as patient compliance is poor, be not subject to the impact of the lives such as patient moving, thereby can overcome the deficiency of external remote ecg monitoring.The implanted telemonitoring System of ECG Data volume of present stage is little, and battery life is long, and the information obtaining is many, writing time, length even can reach the several years, can obtain the reliable electrocardiosignal of continous-stable, also some has auto-alarm function, is subject to the recommendation of the relevant association of Europe and american heart.There is at present several Implantable ECG detected electrons equipment to be applied to abroad clinical, as Medtronic Reveal and St.Jude Confirm.But current these Implantable ECG monitoring equipment battery capacities are still less than normal, can only there is the electrocardiogram in a period of time of front and back by recording events; Some electrocardiogram is only for singly leading, and definitely diagnosis room is fast; Easily be disturbed, have false positive signal possibility; Need doctor to make reasonable judgement; The frequent false alarm of signal intervention and all depositing, affect battery life; Without any treatment function.Due to needs operations, generally patient is only difficult to implant remote electrocardiogram monitor equipment for cardiac monitoring or diagnosis, thereby its application is also limited.
3. have the pacemaker of remote ecg monitoring concurrently: utilize mobile communications network to carry out ecg information transmission, some current pacemakers, particularly the pacemaker (ICD) of the automatic defibrillating function of band of a new generation, with the following cardiac resynchronization therapy pacemaker (CRT-D) of automatic defibrillating function etc., be all furnished with telemonitoring System of ECG Data, can be used as remote electrocardiogram monitor.Pacemaker and ICD etc. all can store certain cardiac diagnosis and electrode information, especially can record the even relevant parameters of heart failure of atrial fibrillation, ventricular arrhythmia.Current pacemaker remote ecg monitoring has the trigger-type of event, can be also that patient's on-demand person opens communication process, thereby makes doctor carry out long-range program control on the net according to the parameter of the monitoring of accepting.There are at present Home Monitoring System, Medtronic Carelink Network, Latitude and Housecall Plus Remote patient Monitoring etc. to be applied to clinical.A new generation's long distance monitoring is to carry out wireless system, can automatic transmission information arrive staff or doctor, comprising: device-dependent information, and problem (finding arrhythmia conditions, battery and electrode) and electrocardiogram, find the arrhythmia such as asymptomatic atrial fibrillation; Maximum advantage is the arrhythmia that finds that there is potential risk.Transmit ECG information in real-time heart in every month or season; The electrocardiogram that causes symptom is downloaded (including an ICD discharge), or each season downloads.
Have the current main ICD of being used in of the pacemaker field of remote ecg monitoring concurrently.ICD has identification ventricular arrhythmia and defibrillating function, be the Therapeutic Method that reduces SCD incidence rate, but ICD also exists a lot of shortcomings: expensive, China's Most patients can not be born and can not be benefited because of economy; Life-span is short, and about 5 years, some needs of patients was repeatedly changed; Often there will be fault, as inappropriate electric shock, unnecessary electric shock and electrode cable fault etc.Inappropriate electric shock refers to the electric shock of being brought out by non-lethal arrhythmic events, as false sense is known etc.; And unnecessary electric shock refers to that some rapidity chamber speed can be stopped by other modes, as ATP stops, and do not need peb treatment, thereby alleviate patient suffering.Have and studies show that rapidity VT accounts for ARR 76% of all triggering ICD electric shocks.Therefore the developing direction of ICD is not only volume miniaturization, the more important thing is and reduces inappropriate electric shock and unnecessary electric shock, monitors the timely function that can be conducive to ICD and adjusts, thereby reduce bad electric discharge by remote ecg.
Yet, even if the Home Monitor monitoring system of ICD does not have heart real time monitoring function mostly, by doctor, in person do not processed yet.Expensive, and because itself still have adverse side effects such as misplacing electricity, the clinical practice of therefore applying them is still subject to certain restrictions.Patient for some reversibility causes of disease is difficult to accept this method, as patient, is difficult to because only monitor and implantation instrument, and patient also unlikely implants ICD because of monitoring, diagnosing.
At present relevant with cardiac stimulation, monitoring in a word have 2 kinds of products: the first is remote electrocardiogram monitor, comprises implanted and non-built-in mode, but all there is no real-time cardiac bioelectricity monitoring function, and without any treating function; The second is pacemaker, and particularly with the pacemaker ICD of automatic defibrillating function, yet these pacemakers and ICD all need long-term implantation, and all there is no remote real-time electrocardio monitoring function, more cannot by doctor, in person be controlled pacemaker and be made its pace-making in vitro.Apparatus with real time remote cardiac monitoring external control cardiac pacing also lacks at present.
IEEE 802.15.4 has described Physical layer and the media access control protocol of low rate wireless personal local area network.It belongs to IEEE 802.15 working groups.IEEE 802.15.4 is ZigBee, WirelessHART, and the basis of MiWi standard.
ZigBee is a kind of wireless network protocol of low speed short-distance transmission.Zigbee protocol is respectively Physical layer (PHY), MAC layer (MAC), transport layer (TL), Internet (NWK), application layer (APL) etc. from top to bottom.Wherein Physical layer and MAC layer are followed the regulation of IEEE 802.15.4 standard.
Utility model content
The purpose of this utility model is to provide a kind of heart real time to stimulate, guard wireless module.
For achieving the above object, the technical scheme that this utility model is taked is: a kind of heart real time stimulates, monitoring wireless module, electronic component kit by insulating package, stimulating electrode, mornitoring electrode forms, and electronic component kit comprises the sub-battery of lithium, low-power consumption microprocessor, bio electricity harvester, constant-current source stimulator, antenna; The sub-battery of lithium is powered to the circuit in electronic component kit; Low-power consumption microprocessor has radio transmission-receiving function; Mornitoring electrode is connected with bio electricity harvester, gathers electrocardiogram (ECG) data and enters low-power consumption microprocessor, and low-power consumption microprocessor sends electrocardiogram (ECG) data by antenna; Antenna reception stimulates control instruction, sends low-power consumption microprocessor to, and low-power consumption microprocessor is controlled constant-current source stimulator, and constant-current source stimulator is connected with stimulating electrode and exports stimulus signal.
This utility model has following beneficial effect: low power dissipation electron components and parts, carry the sub-battery of high-energy lithium for power supply, module can be implanted in humans and animals body, not only can carry out real-time cardiac bioelectricity monitoring, can also utilize its cardiac stimulation circuit, by remote control, at any time humans and animals body be stimulated in vitro.
One of optimal technical scheme of the present utility model: above-mentioned bio electricity harvester according to signal flow to by elementary low-power consumption three amplifier differential amplifiers, high-pass filtering circuit, low-pass filter circuit, wave trap, final stage low-power consumption three amplifier differential amplifiers, A/D converter is composed in series.
Two of optimal technical scheme of the present utility model: above-mentioned constant-current source stimulator is comprised of D/A converter and the two-way stimulation circuit of constant-current source, D/A converter drives the two-way stimulation circuit of constant-current source.
Three of optimal technical scheme of the present utility model: the radio transmission-receiving function of above-mentioned low-power consumption microprocessor is followed ZigBee wireless network protocol.
Four of optimal technical scheme of the present utility model: above-mentioned stimulating electrode adopts visceral pericardium stimulating electrode.
Five of optimal technical scheme of the present utility model: above-mentioned stimulating electrode adopts common endocardium stimulating electrode.
Another object of the present utility model is to provide a kind of heart real time to stimulate, guard wireless system.
For achieving the above object, the technical scheme that this utility model is taked is: a kind of heart real time stimulates, monitoring wireless system, by implant module, wireless transceiver, computer forms, implant module is that above-mentioned a kind of heart real time stimulates, monitoring wireless module, and computer has cardiac monitoring, stimulatory function; Computer accepts by wireless transceiver the electrocardiogram (ECG) data that implant module transmits, and controls implant module and sends stimulus signal.
This utility model has following beneficial effect: owing to adopting, a kind of heart real time stimulates, monitoring wireless module, in implantable humans and animals body, not only can utilize native system to carry out real-time cardiac bioelectricity monitoring, can also utilize its stimulating system, operating in vitro native system stimulates humans and animals body at any time.
One of preferred version of the present utility model: above-mentioned implant module and wireless transceiver are followed ZigBee wireless network protocol.
Two of preferred version of the present utility model: above-mentioned a kind of heart real time stimulates, monitoring wireless system comprises distance transmission system, and wireless transceiver is by distance transmission system and computer communication.
Accompanying drawing explanation
Fig. 1 is that described a kind of heart real time stimulates, monitoring wireless module structured flowchart.
Fig. 2 is that described a kind of heart real time stimulates, monitoring wireless module theory diagram.
Fig. 3 is that described a kind of heart real time stimulates, monitoring wireless system theory diagram.
The specific embodiment
Below in conjunction with embodiment and with reference to accompanying drawing, this utility model is further described.
embodiment 1
The present embodiment is realized a kind of heart real time stimulates, guards wireless module.
Referring to a kind of heart real time described in accompanying drawing 1, stimulate, guard wireless module structured flowchart.Stimulate, guard a wireless module, by the electronic component kit of insulating package, stimulating electrode, mornitoring electrode forms, and electronic component kit comprises the sub-battery of lithium, low-power consumption microprocessor, bio electricity harvester, constant-current source stimulator, antenna; The sub-battery of lithium is powered to the circuit in electronic component kit; Low-power consumption microprocessor has radio transmission-receiving function; Mornitoring electrode is connected with bio electricity harvester, gathers electrocardiogram (ECG) data and enters low-power consumption microprocessor, and low-power consumption microprocessor sends electrocardiogram (ECG) data by antenna; Antenna reception stimulates control instruction, sends low-power consumption microprocessor to, and low-power consumption microprocessor is controlled constant-current source stimulator, and constant-current source stimulator is connected with stimulating electrode and exports stimulus signal.
The current low rate wireless personal local area network comparative maturity based on IEEE 802.15.4.IEEE 802.15.4 is ZigBee, WirelessHART, and the basis of MiWi standard.ZigBee is a kind of wireless network protocol of low speed short-distance transmission.For example the low-power consumption microprocessor CC2530 of company of Texas Instrument (TI) just has ZigBee radio transmission-receiving function.Therefore above-mentioned heart real time stimulates, monitoring wireless module can be that core forms by the low-power consumption microprocessor CC2530 of company of Texas Instrument (TI).CC2530 is a real SOC(system on a chip) (SoC) solution for IEEE 802.15.4, ZigBee and RF4CE application.It can set up powerful network node with low-down total material cost.CC2530 combines the premium properties of leading RF transceiver, enhancement mode 8051 CPU of industrywide standard, In-System Programmable flash memory, 8-KB RAM and many other powerful functions.CC2530 has four kinds of different flash versions: CC2530F32/64/128/256, has respectively the flash memory of 32/64/128/256KB.CC2530 has different operational modes, makes it especially adapt to the system of super low-power consumption requirement.Conversion time between operational mode is short has further guaranteed low energy expenditure.CC2530F256 combines leading golden unit ZigBee protocol stack (the Z-StackZigBee solution of Texas Instrument.CC2530F64 combines the golden unit RemoTI of Texas Instrument, and a powerful and complete ZigBee RF4CE Long-distance Control solution is provided better.
Referring to a kind of heart real time described in accompanying drawing 1, stimulate, guard wireless module theory diagram.Bio electricity harvester according to signal flow to by elementary low-power consumption three amplifier differential amplifiers, high-pass filtering circuit, low-pass filter circuit, wave trap, final stage low-power consumption three amplifier differential amplifiers, A/D converter is composed in series.Constant-current source stimulator is comprised of D/A converter and the two-way stimulation circuit of constant-current source, and D/A converter drives the two-way stimulation circuit of constant-current source.According to human body and animal organisms electrocardio feature, high-pass filtering circuit is set to the above frequency wave of 0.3Hz to be passed through; Low-pass filter circuit is set to the following frequency wave of 100Hz to be passed through; Wave trap stops 50Hz frequency wave.For guaranteeing sampling precision, A/D adopts the high-precision adc of 12,12 analog-digital converters that adopt CC2530 to carry in the present embodiment.
Above-mentioned module can be implanted in organism, mainly 3 parts, consists of: 1. by the implantation main body that includes electronic component and battery of insulating package; 2. 2 electrocardiographicmonitoring monitoring electrodes that thoroughly do away with edge, an anode wherein, another root is negative electrode; 3. stimulating electrode (can be used pacemaker electrode, have 2 kinds of pacing electrodes: a kind of is visceral pericardium stimulating electrode, have 2; Another kind is common endocardium stimulating electrode).
embodiment 2
The present embodiment is realized a kind of heart real time stimulates, guards wireless system.
Referring to a kind of heart real time described in accompanying drawing 3, stimulate, guard wireless system theory diagram.Stimulate, guard a wireless system, by implant module, wireless transceiver, computer forms, and implant module is that above-mentioned a kind of heart real time stimulates, monitoring wireless module, and computer has cardiac monitoring, stimulatory function; Computer accepts by wireless transceiver the electrocardiogram (ECG) data that implant module transmits, and controls implant module and sends stimulus signal.
As preferred selection implant module and wireless transceiver, follow ZigBee wireless network protocol; Said system comprises distance transmission system, and wireless transceiver is by distance transmission system and computer communication.Distance transmission system can be based on wireless 3G, GPRS network, or the broadband network of telecommunications, can select according to practical situation.Certainly local computer and remote computer also can exist simultaneously, to facilitate different application scenarios to use.
The process of establishing of native system is as follows: under anesthesia situation, implant module is implanted to organism skin lower floor, wherein cardiac monitoring positive electrode is implanted in heart lower left, the negative electrode of another root is implanted in heart upper right side, stimulating electrode is sent into right ventricle through jugular vein or subclavian vein, or opens breast and be sewn to visceral pericardium.Wireless transceiver is placed in 10 meters of implanted devices, connects with the mains, and opens computer and system, and computer can show electrocardiogram in real time, and connects time sequencing preservation hereof, can be for analyzing.
The above is only preferred implementation of the present utility model; it should be pointed out that for those skilled in the art, do not departing under the prerequisite of this utility model principle; can also make some improvement and supplement, these improvement and supplement and also should be considered as protection domain of the present utility model.

Claims (7)

1. heart real time stimulates, guards a wireless module, by the electronic component kit of insulating package, stimulating electrode, mornitoring electrode forms, and it is characterized in that: described electronic component kit comprises the sub-battery of lithium, low-power consumption microprocessor, bio electricity harvester, constant-current source stimulator, antenna; The sub-battery of described lithium is powered to the circuit in described electronic component kit; Described low-power consumption microprocessor has radio transmission-receiving function; Described mornitoring electrode is connected with bio electricity harvester, gathers electrocardiogram (ECG) data and enters low-power consumption microprocessor, and low-power consumption microprocessor sends electrocardiogram (ECG) data by described antenna; Described antenna reception stimulates control instruction, sends low-power consumption microprocessor to, and described low-power consumption microprocessor is controlled constant-current source stimulator, and constant-current source stimulator is connected with stimulating electrode and exports stimulus signal.
2. a kind of heart real time according to claim 1 stimulates, guards wireless module, it is characterized in that: described bio electricity harvester according to signal flow to by elementary low-power consumption three amplifier differential amplifiers, high-pass filtering circuit, low-pass filter circuit, wave trap, final stage low-power consumption three amplifier differential amplifiers, A/D converter is composed in series.
3. a kind of heart real time according to claim 1 stimulates, guards wireless module, it is characterized in that: described constant-current source stimulator is comprised of D/A converter and the two-way stimulation circuit of constant-current source, and described D/A converter drives the two-way stimulation circuit of described constant-current source.
4. a kind of heart real time according to claim 1 stimulates, guards wireless module, it is characterized in that: described stimulating electrode adopts visceral pericardium stimulating electrode.
5. a kind of heart real time according to claim 1 stimulates, guards wireless module, it is characterized in that: described stimulating electrode adopts endocardium stimulating electrode.
6. a heart real time stimulates, guards wireless system, by implant module, wireless transceiver, computer forms, it is characterized in that: described implant module be described in claim 1 a kind of heart real time stimulate, monitoring wireless module, described computer has cardiac monitoring, stimulatory function; Described computer accepts by described wireless transceiver the electrocardiogram (ECG) data that described implant module transmits, and controls described implant module and sends stimulus signal.
7. a kind of heart real time according to claim 6 stimulates, guards wireless system, it is characterized in that: comprise distance transmission system, described wireless transceiver is by described distance transmission system and described computer communication.
CN201320198714.9U 2013-04-19 2013-04-19 Real-time electro-cardio stimulating and monitoring wireless module and system Expired - Fee Related CN203425379U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103252020A (en) * 2013-04-19 2013-08-21 上海交通大学医学院附属新华医院 Real-time electrocardio-stimulation monitoring wireless module and system and ventricular tachycardia inducing and stopping method
WO2017147222A1 (en) * 2016-02-26 2017-08-31 Medtronic, Inc. Noninvasive methods and systems of determining the extent of tissue capture from cardiac pacing
US11456062B2 (en) 2013-12-09 2022-09-27 Medtronic, Inc. Noninvasive cardiac therapy evaluation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103252020A (en) * 2013-04-19 2013-08-21 上海交通大学医学院附属新华医院 Real-time electrocardio-stimulation monitoring wireless module and system and ventricular tachycardia inducing and stopping method
US11456062B2 (en) 2013-12-09 2022-09-27 Medtronic, Inc. Noninvasive cardiac therapy evaluation
WO2017147222A1 (en) * 2016-02-26 2017-08-31 Medtronic, Inc. Noninvasive methods and systems of determining the extent of tissue capture from cardiac pacing
US11219769B2 (en) 2016-02-26 2022-01-11 Medtronic, Inc. Noninvasive methods and systems of determining the extent of tissue capture from cardiac pacing

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140212

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