CN203303415U - Integrated infusion container communicated through puncture - Google Patents

Abstract

The utility model provides an integrated infusion container communicated through puncture. The integrated infusion container communicated through puncture comprises a liquid medicine container (1) and a liquid medicine conveyor (2). The integrated infusion container communicated through puncture is characterized in that the liquid medicine container (1) and the liquid medicine conveyor (2) are connected into a whole through a connecting component (4); the connecting component (4) can be a functional part, which is used for connection, of an intrinsic component of the liquid medicine container (1) or the liquid medicine conveyor (2); or, the connecting component (4) can be an independent component used for connection and / or sealing; the liquid medicine container (1) and the liquid medicine conveyor (2) are connected into a whole in the mode that at least a puncture surface (3-1) of an isolation barrier (3) and at least a part of a puncture outfit (2a) are jointly located in a sterile space which is sealed from the outside finally, wherein the part of the puncture outfit (2a) refers to the part (outer wall), which may make contact with liquid medicine in the puncture communication process and the liquid medicine transportation process, of the puncture outfit (2a); a liquid medicine outlet (2c-4) of a liquid medicine conveying space (2c) is sealed from the outside and / or located in a space sealed from the outside, namely located in a sealed package. When the integrated infusion container communicated through puncture is used, external force is applied from the outside of the liquid medicine conveyor (2) and / or the liquid medicine container (1) and acts on the puncture outfit (2a) to make the puncture outfit (2a) move; when sealed from the outside, namely located in a sterile environment, a puncture part (2a-0) of the puncture outfit (2a) penetrates through the puncture surface (3-1) of the isolation barrier (3) and penetrates out of a liquid medicine surface (3-0) of the isolation barrier (3), therefore, the isolation effect of the isolation barrier (3) on the liquid medicine (0) is eliminated, and a liquid medicine accommodating space (1c) is communicated with the liquid medicine conveying space (2c).

Description

Integrated infusion container by the puncture connection

Technical field

This utility model belongs to field of medicaments, is specifically related to a kind of integrated infusion container be communicated with by puncture.

Background technology

The medicinal liquid infusion, comprise conveying and the injection of medicinal liquid, and especially the blood vessel of medicinal liquid input life entity, subcutaneous, intramuscular or be transported to the surfaces such as mucocutaneous, internal organs of life entity, are all clinical therapeutic modalities of commonly using the most as splanchnocoel flushings, washing wound surface etc.Usually, medicinal liquid is stored in medical liquid container, the inner space of medical liquid container is the medicinal liquid spatial accommodation, medical liquid container is medical resin, the bag of the softness that the materials such as glass are made or bottle, medical liquid container has a medicinal liquid output channel at least, this medicinal liquid output channel before use by least one isolation barrier such as rubber stopper etc. to outer closure, isolation barrier quantity no matter, no matter whether gapped between a plurality of isolation barriers, also no matter in the gap between a plurality of isolation barriers, whether also there are liquid or solid-state medicine, the one side of isolation barrier contact medicinal liquid is the medicinal liquid face, the one side that contacts at first space outerpace during use is external contact surface, usually this external contact surface can be run through by a linker with puncture part, externally contact surface can be referred to as puncture face, linker with puncture part is called perforator, aseptic for guaranteeing, puncture face is isolated with space outerpace by a sealing member sealing before use usually, and together experience the sterilization process processing with other parts of medical liquid container, during use, must first this sealing member be removed, expose the puncture face of medical liquid container isolation barrier, fast expose fully puncture particularly important in the face of improving transfusion efficiency, seal designs can be provided to the standby structure of removing fast of being convenient to for crucial, multinomial patent application is arranged for this reason.

The infusion of medicinal liquid also needs the medicinal liquid carrier, usually be referred to as transfusion device, IS08536-4:2004 is described later in detail this, transfusion device be take the hollow flexible pipeline and is main body, one end has a perforator at least, perforator has protective sleeve to avoid in storage and transport process piercing through packing outward and causes pollution and injury, on pipeline, usually connect and be convenient to observe the dropper of drop, the liquid medicine filter of filtering out harmful matter, injection member to filling medicine in pipeline, the functional parts such as venipuncture needle, the transfusion device inner space is communicated with for the medicinal liquid conveying space, pipeline is inserted in the functional part of the adjust flux that can change the local internal diameter of pipeline outward usually, it is flow regulator.Corresponding with this body structure of medical liquid container, when using contractile pocket type or bottle formula medical liquid container, the transfusion device corresponding with it can be with the air inlet device, be referred to as non-air inlet type transfusion device, use contractile non-air inlet type medical liquid container and non-air inlet type transfusion device, medicinal liquid does not need to connect and can complete transfusion with atmosphere, is the infusion model of non-air inlet type.

And the air inlet type needs related air inlet device, the plastic bottle that connection can't be shunk or vial, must puncture enter in medical liquid container and with atmosphere, be communicated with by the road during use, for avoiding polluting common configuration gas filtration parts; Scheme is also arranged by two strands of perforator minute fluid road and gas circuits, during use more for convenience.

As shown in Figure 6, must through following steps: a., remove or open the sealing member of sealing medical liquid container isolation barrier puncture face even if common medicinal liquid infusion process is non-air inlet type, puncture face fully is exposed in the air of environment for use; B. tear or cut off the packing of transfusion device; C. take off the outer protective sleeve of perforator, the puncture part of perforator is exposed in the air of environment for use fully; D. the puncture of perforator part is pierced through to isolation barrier via puncture face, the medicinal liquid spatial accommodation is communicated with the medicinal liquid conveying space in transfusion device, and medicinal liquid enters in transfusion device.

Obviously, step a, c can additionally expend certain hour, medical liquid container and transfusion device are put together also and can additionally expend certain hour, transfusion is in emergency circumstances seized every minute and second usually, the diseases such as especially acute arrhythmia, anaphylactic shock, Acute thrombosis, in infusion process, waste of time may cause missing of rescue opportunity.In addition in a, b, c, tetra-steps of d, puncture part and puncture face that perforator finally contacts medicinal liquid are exposed in the air of environment for use fully in operating process, even if in ward, in situation be also absolutely mostly contain pathogenic microorganism or also have other harmful substances, make medicinal liquid finally probably suffer to pollute in various degree.And when the transfusion behavior occurred in various disaster fields such as Toxicant Leak, fire, earthquake, tsunami, volcanic eruption, this contaminated risk can be multiplied.

Make fast medicinal liquid enter in transfusion device and this process can not carried out under contaminated prerequisite, can greatly meet the demand of clinical treatment and can guarantee fully the safety that the patient infuses if realize.

In addition, in above-mentioned d step, the puncture part of perforator pierces through isolation barrier via puncture face, normally in the situation that carry out without any guiding, be easy to make the perforator diagonal stabbing to cause the not good patency that affects liquid flow in position, also exist because of concentrated risks that causes unexpected injury of the power that arouses attention such as the operator are tired, nervous.

Also have, in practice, often need the other drug of annotating in medical liquid container, be difficult to uprightly but not the medical liquid container of air inlet type is generally pocket type, make comparatively inconvenience of feeding operations.

The medical device that contacts the medicinal liquid that enters human body must be aseptic, because different modes is taked in the sterilizing and transfusion device of medical liquid container sterilizing usually, the former mostly is heat sterilization, and the latter mostly is oxirane or radiated by gamma-ray, waterishlogging in oxirane meeting and medicinal liquid is given birth to reaction and is produced poisonous ethylene glycol, the irradiation medicinal liquid can produce a large amount of free radicals and may change medicinal liquid character, and the heat sterilization infusion vessel, the functional part on it is difficult to tolerance mostly.

200520052560.8, the propositions such as 200520051146.5, use the adapter with easy-to-fold cap that transfusion bag and transfusion device are connected as a single entity, save the perforator parts on the transfusion device and take be advantage, and by transfusion bag and transfusion device sealing and same packing, but this structural design is difficult to realize the effective sterilizing of product, also unexposedly in patent application go out the feasible implementation of science, only rest on a kind of good imagination stage.

And, the integral structure of related perforator can't not realized following functions, usually, medicinal liquid infusion in the medical liquid container be connected with a set of transfusion device is totally the time, also will be replaced by other self-existent medical liquid containers continues infusion treatment, when comparatively commonly even if the amount of liquid medicine residue is more, also can use at any time because of change of illness state the medicinal liquid of other kinds instead, the mode of using instead is that perforator is extracted in original medical liquid container, insert in new medical liquid container, the unrelated perforator of integral structure means can't directly substitute medicinal liquid again.

The utility model content

Technical problem

The purpose of this utility model is, a kind of integrated infusion container be communicated with by puncture is provided, medical liquid container and medicinal liquid carrier are connected as a single entity, can make the puncture part of the perforator on the medicinal liquid carrier under the condition to external seal, penetrate same medicinal liquid isolation barrier to external seal, save the traditional product puncture face that must expose in when operation, take off the step such as perforator overcoat, medicinal liquid enters in transfusion device fast.

Another purpose of the present utility model is, the perforator on the medicinal liquid carrier can break away from from the integrated infusion container be communicated with by puncture, and perforator can insert in other medical liquid container again to be convenient to change and change in time other drug with treatment.

Another purpose of the present utility model is, can pierce through isolation barrier by the perforator on the integrated infusion container of puncture connection with being directed to, and safety is controlled.

Another purpose of the present utility model is, side subchannel by another isolation barrier sealing is set on the medicinal liquid output channel of the integrated infusion container be communicated with by puncturing, can be vertical with the medicinal liquid output channel or become other angles, be convenient in medical liquid container, add other drug under non-erectility.

Also purpose of the present utility model is, when not needing the puncture part is extracted, punctures and partly can be trapped on the medical liquid container of the integrated infusion be communicated with by puncture.

Also purpose of the present utility model is, the aseptic and batch production of the integral body that provides a kind of method to make the integrated infusion container be communicated with by puncture becomes possibility.

Technical scheme

Basic scheme of the present utility model is as follows:

Integrated infusion container by puncture is communicated with, comprise medical liquid container (1), medicinal liquid carrier (2).

Medical liquid container (1) is the bag-shaped or ampuliform of hollow, by medical flexible material sealing moulding or directly injection mo(u)lding, comprise the body 1a of hollow and the channel part 1b of hollow, but body 1a is communicated with the inner space that forms receiving medical liquids with the inner space of channel part 1b be medicinal liquid spatial accommodation (1c), this case is referred to as the first space for convenience of description, medicinal liquid (0) is positioned at medicinal liquid spatial accommodation (1c), medical liquid container (1) has a channel part 1b at least, the inner space of channel part 1b (1b-0) is the medicinal liquid output channel, channel part (1b) is that medical liquid container (1) body (1a) extends or funtion part being recessed to form or be formed by connecting with the body part (1a-1) that forms body (1a) by passage component (1b-1) independently, described medical liquid container (1) can shrink its inner space (1c) with the minimizing of medicinal liquid in transfusion, for non-air inlet type medical liquid container (1).

As Fig. 3,4,5, medicinal liquid carrier (2) comprises perforator (2a), perforator (2a) has the sharp keen puncture section (2a-0) in a shaft-like top with internal path (2c-1) (2a-00) at least, and it is medicinal liquid entrance (2c-0) that the internal path (2c-1) of puncture section (2a-0) has an opening that is positioned at top (2a-00) or adjacent top (2a-00) at least.Medicinal liquid carrier (2) also comprises the medicinal liquid transfer pipeline (2b) of at least one section hollow directly or indirectly be connected with perforator (2a); On medicinal liquid transfer pipeline (2b), can contact and or and connect the parts such as dropper (2b-0), liquid medicine filter (2b-1), puncture needle (2b-3), injection member (2b-4), series winding and or and the inner space (2c-3) of the various parts that connect with the inner space (2c-2) of medicinal liquid transfer pipeline (2b) and the internal path (2c-1) of perforator (2a), jointly form medicinal liquid conveying space (2c), this case is referred to as second space for convenience of description, and medicinal liquid conveying space (2c) has at least one to outward opening, to be medicinal liquid delivery outlet (2c-4).

As Figure 24 etc., at least together the isolation barrier that is easy to be subjected to the puncture effect and eliminates isolation features is sealed the medicinal liquid output channel, medicinal liquid spatial accommodation (1c) and medicinal liquid conveying space (2c) are cut off, isolation barrier avoids medicinal liquid to enter before use in medicinal liquid conveying space (2c), several roads isolation barrier no matter, the one side that isolation barrier directly contacts medicinal liquid is medicinal liquid face (3-0), the one side that in the puncture handshaking procedures, perforator touches at first is puncture face (3-1), as shown in figure 25, when having a plurality of isolation barrier, between isolation barrier if any medicinal liquid, a unit product there will be a plurality of medicinal liquid faces, the medicinal liquid face of the inner space of contact medical liquid container 1 body 1a is only 1, it is the first medicinal liquid face (3-0), medicinal liquid face between isolation barrier is the second medicinal liquid face (33-0), the second medicinal liquid face (33-0) is more than two, also can be divided according to the number of the amount of liquid medicine touched, the medicinal liquid face that the amount of liquid medicine touched is maximum is the first medicinal liquid face (3-0), what take second place is the second medicinal liquid face (33-0), certain the second medicinal liquid face still may be for more than two, when only having one isolation barrier, the another side of puncture face (3-1) is namely medicinal liquid face (3-0), and when more than one isolation barrier, the another side of puncture face (3-1) can be that the medicinal liquid face can not be also the medicinal liquid face.

During use, medicinal liquid (0) in medicinal liquid spatial accommodation (1c) enters medicinal liquid conveying space (2c) by the medicinal liquid input port (2c-0) on the perforator (2a) that passes isolation barrier medicinal liquid face (3-0), and flow out from medicinal liquid delivery outlet (2c-4), to human body corresponding site or other objects, carry.

Medicinal liquid spatial accommodation (1c) and medicinal liquid conveying space (2c) are all aseptic, specifically also comprise that the medial wall of medial wall 1a-10, passage component 1b-1 medial wall (1b-10), medicinal liquid, medicinal liquid carrier (2) each several part of medical liquid container body part 1a-1, the air that may be arranged in wherein are all aseptic.

Further, as Fig. 8, medical liquid container (1) is connected as a single entity by link (4a) with medicinal liquid carrier (2); Link (4a) can be independently for connect and or the parts of sealing, can be also the funtion part for connecting of the intrinsic parts on medical liquid container (1), medicinal liquid carrier (2).

As Figure 12, medical liquid container (1) also can be connected as a single entity by the packing diaphragm with coupling part and the medicinal liquid carrier of medicinal liquid carrier (2), medicinal liquid carrier (2) is positioned at the space 3c that the packing diaphragm seal forms, it is upper that the packing diaphragm can be sealedly connected on medical liquid container 1 passage component 1b-1 lateral wall (1b-11), also on the salable lateral wall (1a-11) that is connected to medical liquid container 1 body part (1a-1).

At least at least a portion of the puncture face of isolation barrier (3-1) and perforator (2a) be co-located at one by link (4a) and or the packing diaphragm 4b finally sterilized space 3c to external seal that participates in forming in, this space is referred to as the 3rd space in this case.

As Fig. 4, at least a portion of described perforator (2a) refers to that perforator (2a) may contact the part of medicinal liquid in puncture handshaking procedures and medicinal liquid course of conveying; Describedly finally the sterilized space 3c of external seal is referred to holding puncture face (3-1) and perforator (2a) may contact the part of medicinal liquid in puncture handshaking procedures and medicinal liquid course of conveying space 3c is connected with other spaces to external seal and aseptic or this space 3c, and other spaces that are connected with this space 3c are still to external seal and aseptic space, the body surface that the medicinal liquid in described sterilized space may be flowed through is all aseptic.

Certainly, the body surface that above-mentioned sterilized space inner liquid medicine can not be flowed through is usually also aseptic, because this part may pollute if any bacterium the part that medicinal liquid may be flowed through; And that general sterilization method also is difficult to realize is optionally sterilizing in a seal cavity, and in this case, also there is no need optionally sterilizing.

As shown in Figure 17, when the medicinal liquid input port (2c-0) on perforator (2a) was sealed by a seal member (2a-02), the puncture face of isolation barrier (3-1) may contact medicinal liquid in puncture handshaking procedures and medicinal liquid course of conveying with perforator (2a) part (outer wall 2a0) was located immediately in the space (3c) of a pair of external seal.

As shown in Figure 16, when without this seal member (2a-02), the puncture face (3-1) that holds isolation barrier is communicated with medicinal liquid conveying space (2c) by the medicinal liquid input port (2c-0) on perforator (2a) with the space (3c) that holds perforator (2a) and may contact the part of medicinal liquid in puncture handshaking procedures and medicinal liquid course of conveying.

Further, as Fig. 8,16, the medicinal liquid delivery outlet (2c-4) of medicinal liquid conveying space (2c) for external sealing state (Fig. 9) and or be positioned at the sterilized space (4c) of a pair of external seal, namely be positioned at one and pack inner space (4c), this space to external seal of having contained at least medicinal liquid delivery outlet (2c-4) is the 4th space 4c of this case.

During use, as shown in accompanying drawing 22,23, external force from medicinal liquid carrier (2) and or medical liquid container (1) outside apply, act on perforator (2a) and make it displacement, the puncture section (2a-0) of perforator (2a) is being also through isolation barrier puncture face (3-1), to penetrate under gnotobasis under the state to external seal, from the medicinal liquid face (3-0) of isolation barrier, pass, isolation barrier is eliminated the buffer action of medicinal liquid (0), medicinal liquid spatial accommodation (1c) is communicated with medicinal liquid conveying space (2c), and medicinal liquid (0) enters in liquid conveying space (2c).Be also, under the prerequisite of not destroying the external sealing in the 3rd space (3c), the puncture section (2a-0) of perforator (2a) breaks through isolation barrier, the first space (1c) is communicated with second space (2c), and in the process of connection, the external sealing in the 4th space (4c) can not destroyed also and can destroy in advance.

The external sealing in described the 3rd space (3c), refer to the sealing of the 3rd space (3c) to the external world outside above-mentioned four spaces, the external sealing that can not destroy the 3rd space (3c) that is communicated with of the 3rd space (3c) and second space (2c) itself.

Described destruction in advance refers to that the packing 4b that will form in advance the 4th space (4c) destroys, second space (2c) may be in communication with the outside, because piercing process is of short duration, the medicinal liquid transfer pipeline is very long, the directivity of liquid flow and a small amount of medicinal liquid of usually can draining before infusion, even if the 3rd space (3c) is in communication with the outside by second space (2c) indirectly, also can not threaten the safety of piercing process, namely can not pollute medicinal liquid.

A kind of situation is arranged, certain one-phase when piercing process, especially final stage, the external sealing in the 3rd space (3c) is destroyed, the 3rd space (3c) directly is communicated with extraneous, but this destruction can not make medicinal liquid have contaminated risk, can be used as a kind of concrete scheme of the present utility model yet, the second embodiment shown in Figure 10.

The above-mentioned aseptic standard that meets the pharmaceuticals industry corresponding requirements that refers to of mentioning, comprise that the requirement to pyrogen is also the requirement of endotoxin content.

Requirement to its residual quantity is also arranged when using ethylene oxide sterilizing.

Described isolation barrier is one can be run through and the clamping force that can produce because of self strain after running through produces the elastomer (3a) of being made by rubber or other materials of sealing effect to the perforator outer wall by perforator.

Described isolation barrier is diaphragm also, this diaphragm can be to be tightly connected and to be formed by parts independently, can be also a chaffy funtion part on medical liquid container (1) or perforator (2), can also be the chaffy funtion part for isolation on a link (4a).

Described isolation barrier can be the combination of elastomer (3a) and diaphragm.

The elastomer of described isolation barrier (3a), but elastic recovery runs through hole after perforator is extracted, and again plays the effect of isolation medicinal liquid.

And when isolation barrier is inelastic body, after it is penetrated, to the perforator outer wall, more specifically to the outer wall of the puncture section of perforator, sealing effect can't be produced or sealing effect is unstable, described sealing effect is unstable refers to that the outer wall of the puncture section of perforator in use and isolation barrier relative motion may occur and cause puncture section outer wall and isolation barrier to produce gap, thereby liquid spills; This kind situation can take the mode of the channel seal that the part of perforator 2a (2a-11) is connected with isolation barrier puncture face 3-1 to prevent that liquid from spilling, as shown in figure 21.

The described integrated infusion container be communicated with by puncture, medical liquid container (1) is connected as a single entity by link 4a with medicinal liquid carrier (2), link 4a can be medical liquid container (1) with medicinal liquid carrier (2) on intrinsic parts on funtion part be used to being connected, by it, medical liquid container (1) and medicinal liquid carrier (2) are connected as a single entity, make the part that may contact medicinal liquid in the puncture handshaking procedures of the puncture face (3-1) that makes at least isolation barrier and perforator (2a) and medicinal liquid course of conveying be co-located in the sterilized space 3c of a pair of external seal.

Described medical liquid container (1) is connected as a single entity by link 4a with medicinal liquid carrier (2), link 4a can be independently for connect and or the parts of sealing, by the relevant portion on itself and medical liquid container (1) and medicinal liquid carrier (2), be tightly connected and form.

Described medical liquid container (1) is connected as a single entity by link 4a with medicinal liquid carrier (2), link 4a packs (4b), packs relevant portion on (4b) and medical liquid container (1) and medicinal liquid carrier (2) and is tightly connected and forms.

The described integrated infusion container be communicated with by puncture, do not destroying isolation barrier puncture face (3-1) and perforator (2a) though may contact the external sealing of the part of medicinal liquid or destroy external sealing, but still can not produce under the prerequisite of the risk of polluting medicinal liquid, push perforator (2a) to isolation barrier and make it partial penetration formula destruction, buffer action is eliminated, and medicinal liquid (0) enters in medicinal liquid conveying space (2c).

The described integrated infusion container be communicated with by puncture, as Figure 21, perforator can also comprise matrix part (2a-1), for with the coupling part on medical liquid container, being connected. also can be connected with link (4a), also can be connected with packing (4b), also can be connected with transfer pipeline (2b).

Coupling part on the matrix part (2a-1) of perforator and medical liquid container or link (4a) are while being connected, can be set to the connection that is easy to damage, can keep before use relatively firmly connecting on the one hand, firmly can remove more easily this connection again in a certain direction in use on the other hand.

The described integrated infusion container be communicated with by puncture, the matrix part (2a-1) of perforator (2a) can also comprise the coupling part (2a-14) that is easy to damage, and is connected with link (4a).

The described integrated infusion container be communicated with by puncture, as shown in figure 21, the matrix part (2a-1) of perforator (2a) can also comprise grip portions (2a-12), the convenient operation person uses.

The described integrated infusion container be communicated with by puncture, the matrix part (2a-1) of perforator (2a) can also comprise targeting part (2a-11), also can with other part synergism, at piercing process guided puncture device, finally make to puncture part accurately and or stab isolation barrier like a cork and risky departing from do not occur; Described risky departing from, its risk refer to stab the outer part of isolation barrier, stab be unfavorable for the isolation barrier be communicated with part, the angle after piercing through not goodly is easy to cause that connection is smooth, be easy to leakage or be easy to break away from etc.

The described integrated infusion container be communicated with by puncture, the matrix part (2a-1) of perforator (2a) can also comprise limit part (2a-10), the length that restriction puncture part enters the first space, also can be used as the indication that puncture puts in place.

The described integrated infusion container be communicated with by puncture, as shown in figure 20, the matrix part (2a-1) of perforator (2a) can also comprise hermetic unit, and for seal-packed appropriate section, being tightly connected, described being tightly connected can be the modes such as bonding, welding.

The described integrated infusion container be communicated with by puncture, as shown in figure 30, the matrix part (2a-1) of perforator (2a) can also comprise anti-separating part (2a-16), be used to meeting certain demand, prevents that perforator from separating with medical liquid container.

The described integrated infusion container be communicated with by puncture, as shown in figure 20, perforator (2a) can also comprise a kind of connection that is easy to separate, the perforator (2a) that penetrates or do not penetrate medical liquid container is exerted oneself to the direction away from medicinal liquid spatial accommodation (1c), perforator (2a) can separate with the seal membrane (3e) that forms the 3rd space (3c) at corresponding hermetic unit (2a-17), makes the perforator (2a) that is connected with medicinal liquid carrier (2) pipeline 2b by puncture, to be communicated with other medical liquid containers.

The described integrated infusion container be communicated with by puncture, as Figure 29-4, can also comprise and limit perforator (2a) activity in case use the unexpected parts (2a-01) that puncture or puncture elsewhere in front storage and transportation process, as Figure 19, the restraint parts (2a-04) that the 3rd space (3c) is outer.

Described integrated infusion container by the puncture connection, as Figure 16,17, can also comprise parts 2a-02, the 2a-03 of protection perforator (2a) puncture part (2a-0) in case use unexpected puncture or puncture elsewhere in front storage and transportation process.

Each funtion part on above-mentioned perforator 2a, can be formed respectively by a plurality of positions on an individual components, also can be formed by a plurality of unit constructions.

The described integrated infusion container be communicated with by puncture, as shown in Figure 13,14, the part that perforator (2a) may contact with medicinal liquid (0) is positioned at an external airtight space 34c, exists freely, and the 3rd space, the 4th space unite two into one in such cases.

The described integrated infusion container be communicated with by puncture, as shown in Figure 13,14, the part that perforator (2a) may contact with medicinal liquid (0) is positioned at an external airtight space 34c, perforator 2a matrix part 2a-1 partly is connected with the miscellaneous part in the He Huogai space, medial wall of the diaphragm that forms this space, coupling part 2a-18 on perforator 2a matrix part 2a-1 can be a place and also can be many places, the 3rd space, the 4th space unite two into one, and also can be separated into two space 3c, 4c by the welding band 4b-14 sealing of seal membrane 4b.

The described integrated infusion container be communicated with by puncture, as shown in figure 17, the part that perforator (2a) may contact medicinal liquid is positioned at the sterilized space (3c) that is participated in a pair of external seal formed by seal membrane (3e), namely with independently the 3rd space (3c) of other spatial separation, the opening (2c-0) of perforator (2a) puncture section (2a-0) is sealed by a seal member (2a-02).

The described integrated infusion container be communicated with by puncture, as shown in figure 16, the part that perforator (2a) may contact medicinal liquid is positioned at a final sterilized space (3c) to external seal that is participated in forming by seal membrane (3e), namely with the 4th space (4c), is communicated with.

The described integrated infusion container be communicated with by puncture, perforator (2a) may with part that medicinal liquid (0) contacts on have at least a path (2c-1) to be connected with medicinal liquid transfer pipeline inner space (2c-2).

The described integrated infusion container be communicated with by puncture, the upper each several part of medicinal liquid carrier (2) can be to be connected as a single entity, and can be also that released state exists, and is connected as a single entity during use; Described being connected as a single entity can be being connected as a single entity of solidity forever, can be also being connected as a single entity of being easy to separate.

The described integrated infusion container be communicated with by puncture, as shown in figure 27, medicinal liquid spatial accommodation (1c) can form multicell through weak soldering, holds respectively variety classes or different shape medicine.

The described integrated infusion container be communicated with by puncture, on medicinal liquid transfer pipeline (2b), be connected with have at least an inner passage to outer connection component, for with the medicine liquid outlet of other self-existent medical liquid containers, partly being connected, shape to outer connection component is corresponding with the medicine liquid outlet part of self-existent medical liquid container, can be puncture structure, helicitic texture, buckle structure, be closely connected etc.; When outer connection component was perforator, its puncture part was positioned at a corresponding guard block.

The described integrated infusion container be communicated with by puncture, the medicinal liquid delivery outlet is sealed by a sealing member.

The described integrated infusion container be communicated with by puncture, the medicinal liquid delivery outlet is positioned at one and packs.

The described integrated infusion container be communicated with by puncture, pipeline major part and medicinal liquid delivery outlet are positioned at one and pack.

The described integrated infusion container be communicated with by puncture, pipeline all is positioned at one and packs, the described medicinal liquid delivery outlet that all comprises.

The described integrated infusion container be communicated with by puncture, medicinal liquid carrier 2 all is positioned at one and packs, the described medicinal liquid delivery outlet that all comprises.

The described integrated infusion container be communicated with by puncture, medical liquid container (1) is upper except the fluid passage that holds isolation barrier, can be connected with at least one fill dosing mouth of pipe.

The described integrated infusion container be communicated with by puncture, as shown in figure 26, medical liquid container (1) holds and on the fluid passage of isolation barrier, is connected with at least one passage shape medicinal liquid and enters and exits mouthpiece (1b-2), and its inner passage (1b-20) is connected with medicinal liquid spatial accommodation 1c.

The described integrated infusion container be communicated with by puncture, as shown in figure 29, medical liquid container (1) is that folded is deposited with the major part of medicinal liquid carrier (2) or medicinal liquid carrier, and doubling is partly soft structure, and the doubling part is outer also can be provided with position limiting structure.

The described integrated infusion container be communicated with by puncture, medical liquid container (1) is deposited for non-doubling with medicinal liquid carrier (2), inner and or outsidely protection is arranged and or limit the parts of relative motion.

A kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, after comprising the following steps: that medical liquid container (1) and medicinal liquid carrier (2) are connected as a single entity and form isolation barrier, in the packing of packing into, can adopt irradiation or oxirane etc. after sealing, carry out integral body sterilizing, again the medicinal liquid sterile filling is entered to medical liquid container (1), sealing fill entrance, by medical liquid container (1) part heat sterilization.

A kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, after medical liquid container (1) and medicinal liquid carrier (2) are connected as a single entity and form isolation barrier, in the packing of packing into, can adopt irradiation or oxirane etc. to carry out integral body after sealing sterilizing, again the medicinal liquid sterile filling is entered to medical liquid container (1), fill inlet seal or heat sterilization medical liquid container (1) part thereupon.

A kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, adopt medicinal liquid carrier (2) packaging film that does not tolerate steam or water-bath, first by the sterilizing a set of at least packaging film that intercepts steam of the outer increase of medicinal liquid carrier (2) packing, can be to aluminize or foil laminated film, again with the medical liquid container that adds medicinal liquid (0) (1) heat sterilization together, can between the packaging film that intercepts steam and medicinal liquid carrier (2) packing, add heat-barrier material or filling gas, guarantee that the thermo-labile parts of composition medicinal liquid carrier (2) are unaffected during heat sterilization.

A kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, after the medical liquid container of the complete medicinal liquid of fill (1) is connected as a single entity with medicinal liquid carrier (2), together heat sterilization or irradiation sterilization.

A kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, after filling liquid be connected as a single entity medical liquid container (1) and medicinal liquid carrier (2), and medicinal liquid carrier (2) is sterilizing, then heat sterilization medical liquid container (1).

A kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, is characterized in that, fills with after liquid medical liquid container (1) heat sterilization, then be connected as a single entity with medicinal liquid carrier (2), medicinal liquid carrier (2) irradiation sterilization.

After a kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, medical liquid container (1) and medicinal liquid carrier (2) are sterilizing respectively, be connected in the sterile procedures district.

After a kind of aseptic method of integrated infusion container be communicated with by puncture that realizes, medical liquid container (1) and medicinal liquid carrier (2) are sterilizing respectively, be connected in the sterile procedures district or in non-sterile operation area, connect heating power or irradiation sterilization connecting portion afterwards.

Beneficial effect

As mentioned above, because the integrated infusion container be communicated with by puncture of realizing according to technical solutions of the utility model is connected as a single entity the medical liquid container of clinical infusion and medicinal liquid carrier, make the puncture part of the perforator on the medicinal liquid carrier under the condition to external seal, can guide to penetrate same medicinal liquid isolation barrier to external seal, save the traditional product puncture face that must expose in when operation, take off the step such as perforator overcoat, under the prerequisite without any contaminated risk, medicinal liquid enters in transfusion device fast.

The structural design of integral type has been save the parts such as overcoat of the outer sealing member of traditional drugs liquid container isolation barrier and the related perforator of medicinal liquid carrier.Can under non-erectility, add other drug in medical liquid container.Perforator on the medicinal liquid carrier is difficult for breaking away from and departing design, meets clinical in safety and the interim different demands of changing medicinal liquid.And can adopt the sterilizing coupling part of heating power mode, make batch production become possibility.

The accompanying drawing explanation

Describe with reference to the accompanying drawings this utility model and embodiment in detail

Fig. 1 is the structural representation of the pocket type medical liquid container of prior art

Fig. 2 is the structural representation of the bottle formula medical liquid container of prior art

Fig. 3 is the structural representation (non-air inlet type) of the medicinal liquid carrier of prior art

Fig. 4 is the partial structurtes schematic diagram of the medicinal liquid input port on the medicinal liquid carrier of prior art

Fig. 5 is the partial structurtes schematic diagram of the medicinal liquid delivery outlet on the medicinal liquid carrier of prior art

Fig. 6 is the medical liquid container of prior art and the schematic diagram of medicinal liquid carrier handshaking procedures

Fig. 7 is the medical liquid container of prior art and schematic diagram after the medicinal liquid carrier is communicated with

Fig. 8 is the structural representation of this utility model the first embodiment

Fig. 9 is the sealed local enlarged diagram of the medicinal liquid delivery outlet of this utility model the first embodiment

Figure 10 is the structural representation of this utility model the second embodiment

Figure 11 is the structural representation of this utility model the 3rd embodiment

Figure 12-1 is structural representation Fig. 1 of this utility model the 4th embodiment

Figure 12-2 are structural representation Fig. 2 of this utility model the 4th embodiment

Figure 13 is the structural representation of this utility model the 5th embodiment

Figure 14 is the sectional perspective schematic diagram of this utility model the 5th embodiment

Figure 15-1 is the flexible connecting structure schematic diagram of this utility model the 6th embodiment

Figure 15-2 are the flexible connecting structure using state schematic diagram of this utility model the 6th embodiment

Figure 16 is a kind of spring limiting structure schematic diagram (also being applicable to the situation of the 5th embodiment) of this utility model the 6th embodiment

Figure 17 is a kind of puncture section guard block structural representation of this utility model the 6th embodiment

Figure 18 is a kind of puncture section limiting component structural representation of this utility model the 6th embodiment

Figure 19 is a kind of puncture section limiting component structural representation be positioned at outside the 3rd space of this utility model the 6th embodiment

Figure 20-1 enters the structural representation in medical liquid container for this utility model the 6th embodiment puncture section

The structural representation in medical liquid container is left for this utility model the 6th embodiment puncture section in Figure 20-2

Figure 21 is the medical liquid container of this utility model the 7th embodiment and the schematic diagram that the medicinal liquid carrier splits

Figure 22 is the medical liquid container of this utility model the 7th embodiment and the schematic diagram that the medicinal liquid carrier is connected as a single entity

Figure 23 is that the puncture of the perforator of this utility model the 7th embodiment partly enters the schematic diagram in medical liquid container

Figure 24 is the schematic diagram before a kind of connection of situation of the medical liquid container of this utility model the 7th embodiment and medicinal liquid carrier joint face

Figure 25 is the schematic diagram after a kind of connection of situation of the medical liquid container of this utility model the 7th embodiment and medicinal liquid carrier joint face

Figure 26 is the schematic diagram (the gateway parts are provided with another gateway parts) of this utility model the 8th embodiment

Figure 27 is the schematic diagram (other the dosing mouth of pipe, multi-chamber-bag) of this utility model the 9th embodiment

The sterilizing schematic diagram of Figure 28 after to be this utility model connect about medical liquid container and medicinal liquid carrier joint face

Figure 29-1 is the schematic diagram of this utility model the tenth embodiment

Figure 29-2 are the local enlarged diagram of this utility model the tenth embodiment

Figure 29-3 are this utility model the tenth embodiment medical liquid container and medicinal liquid carrier released state schematic diagram

Figure 29-4 are this utility model the tenth embodiment medical liquid container and medicinal liquid carrier connection status schematic diagram

Figure 29-5 are this utility model the tenth embodiment puncture section structural representation

Figure 30-1 is schematic diagram before this utility model the 11 embodiment puncture section is used

Figure 30-2 are this utility model the 11 embodiment puncture section using state schematic diagram 1

Figure 30-3 are this utility model the 11 embodiment puncture section using state schematic diagram 2 (puncture section stays while extracting in medical liquid container)

Figure 31-1 is schematic diagram before this utility model the 12 embodiment perforator uses

Figure 31-2 are the rear schematic diagram (perforator can't be extracted) of this utility model the 12 embodiment perforator puncture

The specific embodiment

This utility model the first embodiment is with reference to Fig. 8, medical liquid container 1 is connected with link 4a by passage component 1b-1, isolation barrier is cut off the inner space of passage component 1b-1 and link 4a, the perforator 2a of medicinal liquid carrier 2 be communicated with and infusion process in may contact medicinal liquid part be closed in that a coupling part 2a-14 by link 4a and perforator 2a matrix part 2a-1 is tightly connected and in the space 3c sealed to external world that forms.Space 3c is communicated with second space 2c by the medicinal liquid entrance 2c-0 on the perforator 2a of medicinal liquid carrier 2, second space 2c opening is also that medicinal liquid delivery outlet 2c-4 is positioned at the 4th space 4c that an outer wall by seal membrane 4b and transfer pipeline 2b is tightly connected and forms, but some transfer pipeline 2b-7 is positioned at this space 4c, medicinal liquid delivery outlet 2c-4 can be communicated with space 4c also and can second space 2c and the 4th space 4c be isolated by a packaged unit 2b-8 sealing, and the outer wall of the most of 2b-6 of transfer pipeline 2b is exposed in external environment.

This utility model the second embodiment, with reference to Figure 10, is that with the difference of the first embodiment seal membrane 4b and perforator 2a matrix part 2a-1 outer wall or title outer surface are tightly connected, and the 4th space 4c of formation has contained all medicinal liquid transfer pipeline 2b.

This utility model the 3rd embodiment is with reference to Figure 11, with the difference of the second embodiment be seal membrane 4b with and the part lateral wall of the link 4a that is connected as a single entity of medical liquid container 1 passage component 1b-1 be tightly connected, the 4th space 4c of formation has contained all medicinal liquid transfer pipeline 2b.

This utility model the 4th embodiment is with reference to Figure 12-1, with the difference of the 3rd embodiment, be the 4th space 4c that seal membrane 4b and passage component 1b-1 outer wall are tightly connected and form, medicinal liquid carrier 2 all, link 4a, the passage component 1b-1 of a part and the puncture face 3-1 of isolation barrier be positioned at this space 4c.With reference to Figure 12-2, also can seal membrane 4b and the lateral wall 1a-11 of medical liquid container 1 body part 1a-1 the 4th space 4c that is tightly connected and forms.

This utility model the 5th embodiment is with reference to Figure 13, do not adopt link 4a, and directly by seal membrane 4b and passage component 1b-1 outer wall or with the be tightly connected space 34c of formation of the lateral wall 1a-11 of medical liquid container 1 body part 1a-1, the whole medicinal liquid carrier 2 that has comprised related medicinal liquid input port, delivery outlet in this space, make the 3rd space 3c and the 4th space 4c merge into an external airtight space 34c, perforator 2a may be positioned at the part that medicinal liquid 0 contacts this space 34c, exists freely.Further, as shown in Figure 13,14, perforator 2a may be positioned at the part that medicinal liquid 0 contacts this space 34c, at least a portion 2a-18 of perforator 2a matrix part 2a-1 connects as one with the medial wall 4b-0 appropriate section of the seal membrane 4b that forms this space, and the coupling part 2a-18 on perforator 2a matrix part 2a-1 can be a place and also can be many places.Also can be by the interconnecting of two seal membrane 4b part, this connection preferred weld, produce one or more isolated seal membrane join domain 4b-13, and this kind situation the 3rd space 3c, the 4th space 4c still unite two into one.As Figure 14, can also by two seal membrane 4b part and perforator 2a matrix part 2a-1 on banded connection of coupling part 2a-18, the preferred weld mode forms band 4b-14, by band 4b-14, space 34c is separated into to 3c, space, ，Ji space, two spaces 4c.

This utility model the 6th embodiment is with reference to Figure 15, hold perforator 2a and may contact the space 3c of the part of medicinal liquid in puncture connection and infusion process, the link 3e that this space 3c is made by flexible material and the passage component 1b-1 of medical liquid container 1 and the matrix part 2a-1 of perforator 2a are tightly connected and form, the matrix part 2a-1 that controls perforator 2a during puncture with hands outside seal membrane 3e makes it to advance to the puncture face 3-1 of isolation barrier, as Figure 15-2, link 3e distortion, space 3c shape also changes thereupon, but 3c external sealing in space is constant, ensured the safety of piercing process.Further, link 3e with being connected of matrix part 2a-1 of perforator 2a can be set to the connection that is easy to damage, can keep before use relatively firmly connecting on the one hand, firmly can remove more easily this connection again in a certain direction in use on the other hand, the medicinal liquid carrier 2 separated with link 3e and isolation barrier can be connected on other medical liquid container, as Figure 20-2.

Further, with reference to Figure 16, one limiting component is set in the 3c of space, as the spring 2a-03 accidental movement in restriction perforator 2a storage haulage stage before use, thereby this accidental movement can produce the puncture part 2a-0 of perforator 2a and puncture the risk that link 3e is in communication with the outside space 3c, also can produce the risk of the 2a-0 puncture of puncture part or break-through isolation barrier.As Figure 17, the puncture part 2a-0 that also can apply a guard block 2a-02 parcel perforator 2a especially wraps up top 2a-00, guarantees that before use storage, haulage stage do not cause above-mentioned risk because of accidental movement.As Figure 18, limiting component in the 3c of space can be a part of 1b-19 of passage component 1b-1, also but independently parts are connected with passage component 1b-1, this limiting component 1b-19 partly wraps up the puncture part 2a-0 of perforator 2a especially top 2a-00 spacing, make less external force can't cause this spacing destruction, thereby guarantee that before use storage, haulage stage do not cause above-mentioned risk because of accidental movement.As Figure 19, also can be at space 3c outer setting limiting component 2a-04, the relative motion by limiting channel parts 1b-1 and perforator 2a body portion 2a-1 reaches spacing purpose.As Figure 20-2, being connected of being easy to separate that be connected to of link 3e and perforator 2a body portion 2a-1, while to outfan, exerting oneself, the coupling part 2a-17 of body portion 2a-1 is separated with link 3e.

This utility model the 7th embodiment is with reference to Figure 21, medical liquid container 1 and medicinal liquid carrier 2 split signal, the body 1a of medical liquid container can be that bag can be also bottle, the channel part 1b inner chamber 1b-0 of medical liquid container 1 is sealed by chaffy isolation barrier 31, adjacent with isolation barrier 31 is elastomeric isolation barrier 32, elastomeric isolation barrier 32 embeds in passage component 1b-1 or directly is injected into one with passage component 1b-1, annular raised face 1b-12 is for the medicinal liquid carrier, being connected, and the one side 3-0 of isolation barrier 31 contact medicinal liquids is the medicinal liquid face.

That medicinal liquid carrier 2 is connected with passage component 1b-1 is a link 4a that inner space 3c is arranged, a part of 4a-0 of the link 4a outer wall that medicinal liquid carrier 2 is connected with passage component 1b-1 and packing diaphragm 4b are tightly connected, packing diaphragm 4b peripheral sealing, medicinal liquid carrier 2 are positioned at the space 4c formed by link 4a and packing diaphragm 4b sealing.Holding that space 3c and the link 4a of the 2a-0 of puncture section of perforator 2a and space 4c that packing diaphragm 4b sealing forms can be connected also can be independent separately.

The 2a-0 of puncture section of perforator 2a is positioned at the inner space 3c of link 4a, the external opening in this space is sealed by a chaffy isolation barrier 33, isolation barrier 33 can be the part on link 4a, can be also independently parts and link 4a welding or bond together, the one side of the isolation barrier 33 subtend puncture 2a-0 of section is puncture face 3-1, annular raised face 1b-12 on the another side 33-1 of isolation barrier 33 and the passage component 1b-1 of medical liquid container 1 is tightly connected, this being tightly connected can be sweat soldering, namely by the contact hot plate, first thawing is to a certain degree occurred in the annular raised face 1b-12 on the another side 33-1 of isolation barrier 33 and passage component 1b-1, thereby again two faces of molten condition are pressed together, realize being tightly connected, usually this being tightly connected is firmly.

If in the sterile procedures district, carried out this connection, and two faces that connect itself are also aseptic together with isolation barrier 32, and the present embodiment can be realized clinical aseptic requirement; Concrete is by advance medical liquid container and medicinal liquid carrier being placed in respectively in one or more layers packs, again by whole packaging sterilizing, make two faces that connect itself reach aseptic and remove respectively packing by the mode of sterile procedures district routine together with isolation barrier 32, then carry out this connection in the sterile procedures district.

This utility model of realizing after connecting as shown in figure 22.

Again as shown in figure 21, the corresponding coupling part 4a-1 of the matrix part 2a-1 of perforator 2a and link 4a is connected to the connection that is easy to damage, and the matrix part 2a-1 of perforator 2a can make the coupling part 2a-14 of the matrix part 2a-1 of perforator 2a separate with link 4a without too large power during to medical liquid container 1 direction motion.

For in puncture, leading reliably, the matrix part 2a-1 of perforator 2a has a columned level and smooth spigot surface 2a-11, and this spigot surface 2a-11 forms guiding with the interior sidewall surface 4a-0 of link 4a and coordinates.

The matrix part 2a-1 of perforator 2a is provided with limit part 2a-10 towards an end of medical liquid container 1, this limit part 2a-10 can be also one or more outstanding isolated planes of an integral planar, and during puncture, this limit part 2a-10 props up at first the puncture face 3-1 of isolation barrier and stops the 2a-0 of puncture section of perforator 2a to continue to advance in medicinal liquid spatial accommodation 1c.In conjunction with the thickness of isolation barrier, the distance between most advanced by the 2a-0 of the puncture section top 2a-00 that limit part 2a-10 and perforator 2a are set can be controlled the length that the 2a-0 of puncture section of perforator 2a enters medicinal liquid spatial accommodation 1c.

Figure 23 is that the puncture of the perforator of this utility model the 7th embodiment partly enters the schematic diagram in medical liquid container, whole piercing process is all to carry out under the prerequisite of the external sealing of the 2a-0 of puncture section that guarantees puncture face 3-1 and perforator 2a, thereby has eliminated the contaminated risk of medicinal liquid fully.Further, the matrix part 2a-1 of perforator 2a contacts with the medial wall sealing of link 4a when puncture procedure completes near the part of 2a-12, can prevent the pollution of outside air to the perforator 2a puncture 2a-0 of section and isolation barrier puncture face 3-1 in infusion process, when extracting the 2a of puncture section and being connected to other medical liquid containers, safety increases.

Figure 24 illustrates a kind of situation of medical liquid container and medicinal liquid carrier joint face of this utility model the 7th embodiment, the one side of elastomeric isolation barrier 32 contacts with medicinal liquid as medicinal liquid face 3-0, the another side of elastomeric isolation barrier 32 is by chaffy isolation barrier 31 sealings, what with isolation barrier 31, be connected is the annular raised face 1b-12 of passage component 1b-1, the length of the ledge 1b-13 of annular raised face 1b-12 is larger, after making its joint face 33-1 with the link 4a of medicinal liquid carrier be connected, form middle lacuna 3d as shown in figure 25, in middle lacuna 3d, gas can be arranged, also liquid can be arranged, this liquid can be medicinal liquid, when being medicinal liquid, isolation barrier 31 all has a medicinal liquid face with isolation barrier 33, be called the second medicinal liquid face 31-0 and the 3rd medicinal liquid face 33-0, and the one side that elastomeric isolation barrier 32 contacts with medicinal liquid is the first medicinal liquid face, the first medicinal liquid face is the maximum one side of contact medicinal liquid.

When in middle lacuna 3d, liquid is not medicinal liquid, be referred to as the second liquid level 31-0 and the 3rd liquid level 33-0, conduction of heat when being filled with liquid can being conducive to this lacunose coupling part heat sterilization in middle lacuna 3d, the medicinal liquid that is filled with function also can be used for other have in requisition for purposes.

The 8th embodiment as shown in figure 26, the medicinal liquid that is connected with at least one passage shape on the passage component 1b-1 of formation medical liquid container 1 channel part 1b enters and exits mouthpiece 1b-2, the inner passage 1b-20 of parts 1b-2 is connected with medicinal liquid spatial accommodation 1c, inner passage 1b-20 opening is cut off by least one isolation barrier 3a, isolation barrier 3a also is provided with a packaged unit parts 1b-3 outward, for ease of opening, can be provided with handle or draw ring etc. on packaged unit 1b-3.Parts 1b-2 can or angled setting vertical with the main shaft of passage component 1b-1, but during making can with passage component 1b-1 one-body molded also independently parts with passage component 1b-1, be formed by connecting again, owing to before using and in use procedure, all existing to the demand that adds or extract out medicine in medical liquid container 1, such design can put down under sleeping state medical liquid container 1 especially before use, use the instrument such as syringe pierce through isolation barrier 3a by top or directly over can complete the operation that adds or extract medicine out, and do not need medical liquid container 1 upright.Certainly also various selection of isolation barrier 3a, as the elastomer with central self-closing gap that similar patent CN100471535C, US5603706, US5501426 etc. describe, be not limited to the type that punctures and be communicated with.

The 9th embodiment as shown in figure 27, the weak weldering isolation barrier 3b that is easy to peel off that the medicinal liquid spatial accommodation 1c tunicle of medical liquid container 1 medical liquid container 1 body 1a-1 on chip is welded to each other formation is divided into two medicinal liquid spatial accommodation 1c-1, 1c-2, can deposit respectively different medicines, in its herb liquid spatial accommodation 1c-1, deposit Powdered solid-state drug 0-1 such as various types of antibiotic etc., medicinal liquid spatial accommodation 1c-2 internal memory tapping state medicine 0-2, during use, firmly push the outer body 1a-1 part of medicinal liquid spatial accommodation 1c-2, the pressure of medicinal liquid makes weak weldering isolation barrier 3b destroy, medicinal liquid 0-2 enters medicinal liquid spatial accommodation 1c-1 powdery medicine 0-1 is wherein dissolved, by puncture, be communicated with the final outwards conveying of the laggard medicinal liquid conveying space 2c of entering.

Any embodiment of the present utility model, except passage component 1b-1, the medicinal liquid that all can be connected with one or more hollows on medical liquid container 1 enters and exits mouthpiece 1d (also claiming the fill dosing mouth of pipe), inner passage 1d-0 is communicated with medicinal liquid spatial accommodation 1c, and cut off by least one isolation barrier 3f, isolation barrier 3f also is provided with a packaged unit parts 1d-1 outward, for ease of opening, can be provided with handle 1d-10 or draw ring etc. on packaged unit 1d-1.

Figure 28 is that this utility model is a kind of about the sterilizing schematic diagram after medical liquid container and the connection of medicinal liquid carrier joint face, usually there are the medical supplies of aseptic requirement to advocate terminally sterilised treatment principle, after also namely completing assembling and sealing, adopt reliable sterilizing means to give sterilization treatment, when medical liquid container 1 of the present utility model and medicinal liquid carrier 2 all adopt corresponding mode sterilization treatment respectively, as medical liquid container 1, adopt water-bath or steam heat sterilization, medicinal liquid carrier 2 adopts oxirane or irradiation sterilization, after the two connects by joint face, needing terminally sterilised position is joint face and adjacent peripheral part 5-0, the final sterilization of product becomes local design by integral body and greatly reduces sterilizing difficulty, a kind of method is: joint face and adjacent peripheral part 5-0 are put into to a heat sterilization device 5, heat transfer component 5-1 approaches or directly contacts with 5-0, heating power is reached to joint face and adjacent peripheral part 5-0, finally reach the part that may contact and pollute medicinal liquid in puncture connection and use procedure aseptic.This part comprises that at this schematic diagram joint face 33-1,31-1 and 3d， inner space, inner space 3d also can be because closely welding and eliminate.Certainly along with the difference of coupling part, the partial shape structure that need to reach aseptic requirement is corresponding difference also, but from outside, inwardly carries out heat conducting heat sterilization as long as the parameters such as temperature, time are appropriate, and any shape and structure all can be realized aseptic.

A kind of concrete mode of heating is to be filled with the conduction oil of 135 ℃ by the circulation line 5-10 inside to heat transfer component 5-1, make heat transfer component 5-1 temperature progressively also reach 135 ℃ of left and right, contact joint face and adjacent peripheral part 5-0 tens of minutes, be generally 15 minutes, thereby realize the heat sterilization of product part.For in batches sterilizing consideration, heat transfer component 5-1 is divided into two parts 5-11,5-12 at least, after two parts are involutory with need sterilizing part 5-0 conformal, after sterilization time reaches, two parts 5-11, the 5-12 of heat transfer component 5-1 are opened product are taken out and gets final product.

This utility model the tenth embodiment as shown in figure 29, medical liquid container 1 and medicinal liquid carrier 2 are connected as a single entity by seal membrane 3e, seal membrane 3e is by hermetic unit 3e-0, 3e-1 is tightly connected with the corresponding outer surface part of the matrix part 2a-1 of the appropriate section of the passage component 1b-1 outer wall 1b-12 of medical liquid container 1 and perforator 2a respectively, formed space 3c, this space 3c has comprised the puncture face 3-1 of elastomeric isolation barrier 32 and the 2a-0 of puncture section of perforator 2a at least, outer can the setting of the 2a-0 of puncture section prevents that sharp keen top 2a-00 accident from puncturing the guard block 2a-01 at seal membrane 3e and other positions, guard block 2a-01 can be connected as a single entity with the matrix part 2a-1 of perforator 2a, space in guard block 2a-01 holds the 2a-0 of puncture section and makes sharp keen top 2a-00 can't contact miscellaneous part, guard block 2a-01 also has a pressing part 2a-010, the pressing part 2a-010 that presses guard block 2a-01 to seal membrane 3e direction or vertical direction during use makes it to break away from matrix part 2a-1, exposing the 2a-0 of puncture section stabs the puncture face 3-1 of elastomeric isolation barrier 32 and makes it to run through elastomeric isolation barrier 32.

Passage component 1b-1 and perforator 2a that this utility model the tenth embodiment can be designed to medical liquid container 1 have certain distance, seal membrane 3e therebetween can fold, thereby realizing the effect that medical liquid container 1 and 2 stacks of medicinal liquid carrier are placed, can be also on horizontal direction, to reduce the parking space of product at certain orientation.

The 3rd space 3c and the 4th space 4c of the present embodiment can cut off fully, and a kind of mode of partition is that guard block 2a-01 seals the medicinal liquid entrance 2c-0 of the 2a-0 of puncture section of perforator 2a, and opens this path when removing guard block 2a-01.The 3rd space 3c also can be communicated with the 4th space 4c, the mode be communicated with can be by the medicinal liquid entrance 2c-0 of the 2a-0 of puncture section of perforator 2a, can be also by the inner passage 2a-13 of perforator 2a matrix part 2a-1, at perforator 2a matrix part 2a-1, the circulation that passage can be convenient to oxirane when sterilizing is set.

This utility model the 11 embodiment as shown in figure 30, the 2a-0 of puncture section of perforator 2a and matrix part 2a-1 are flexibly connected, and this connection is directive, described directivity refers to that the 2a-0 of puncture section is firmly with being connected of matrix part 2a-1 when perforator 2a moves to the medical liquid container direction, to the buckle part 2a-16 deviated from medical liquid container direction when motion 2a-0 of puncture section, the 2a-0 of puncture section is separated with matrix part 2a-1, the 2a-0 of puncture section is trapped in medical liquid container 1.

This utility model the 12 embodiment as shown in figure 31, the 2a-0 of puncture section of perforator 2a and matrix part 2a-1 are connected as a single entity and are synchronized with the movement, but the difficulty or ease of motion are directive, described directivity refers to that when perforator 2a moves to the medical liquid container direction 2a-0 of puncture section and matrix part 2a-1 can reach the position of expection, and a part of 4a-4 on a part of 2a-14 connected component 4a that deviates from medical liquid container direction when motion matrix part 2a-1 stops, perforator can't be extracted or be difficult to and extract.

Claims (17)

1. the integrated infusion container be communicated with by puncture, comprise medical liquid container (1), medicinal liquid carrier (2); Medical liquid container (1) comprises the medical liquid container body, for hollow is bag-shaped or ampuliform, by medical flexible material sealing moulding or directly injection mo(u)lding, being formed with the inner space of receiving medical liquids at least is medicinal liquid spatial accommodation (1c), medicinal liquid (0) is positioned at medicinal liquid spatial accommodation (1c), and medicinal liquid spatial accommodation (1c) has a medicine liquid outlet at least; Medicinal liquid carrier (2) comprises perforator (2a), perforator (2a) has the sharp keen puncture section (2a-0) in a shaft-like top with internal path (2c-1) (2a-00) at least, and it is medicinal liquid entrance (2c-0) that the internal path (2c-1) of puncture section (2a-0) has an opening that is positioned at top (2a-00) or adjacent top (2a-00) at least; Medicinal liquid carrier (2) also comprises the medicinal liquid transfer pipeline (2b) of at least one section hollow directly or indirectly be connected with perforator (2a); On medicinal liquid transfer pipeline (2b), can contact and or and connect the parts such as dropper (2b-0), liquid medicine filter (2b-1) and puncture needle (2b-3), series winding and or and the inner space (2c-3) of the various parts that connect with the inner space (2c-2) of medicinal liquid transfer pipeline (2b) and the internal path (2c-1) of perforator (2a), jointly form medicinal liquid conveying space (2c), medicinal liquid conveying space (2c) has at least one to outward opening, to be medicinal liquid delivery outlet (2c-4); At least together the isolation barrier that is easy to be subjected to the puncture effect and eliminates isolation features is cut off medicinal liquid spatial accommodation (1c) and medicinal liquid conveying space (2c), isolation barrier avoids medicinal liquid to enter before use in medicinal liquid conveying space (2c), the one side that isolation barrier directly contacts medicinal liquid is medicinal liquid face (3-0), and the one side that in the puncture handshaking procedures, perforator touches at first is puncture face (3-1); The part of medical liquid container body contact medicinal liquid and the perforator (2a) of medicinal liquid carrier, medicinal liquid transfer pipeline (2b) may contact the part of medicinal liquid in handshaking procedures and medicinal liquid conveying, part or all of outer wall and the inwall that may contact medicinal liquid of perforator, the medial wall of medicinal liquid transfer pipeline is all aseptic; Medicinal liquid spatial accommodation (1c) and medicinal liquid conveying space (2c) are all aseptic; It is characterized in that, medical liquid container (1) is connected as a single entity by link (4) with medicinal liquid carrier (2); Link (4) can be independently for connect and or the parts of sealing, can be also the funtion part for connecting of the intrinsic parts on medical liquid container (1) medicinal liquid carrier (2); At least the puncture face of isolation barrier (3-1) is co-located in a final sterilized space to external seal with at least a portion of perforator (2a), and at least a portion of described perforator (2a) refers to that perforator (2a) may contact the part of medicinal liquid in puncture handshaking procedures and medicinal liquid course of conveying; The medicinal liquid delivery outlet (2c-4) of medicinal liquid conveying space (2c) for external sealing state and or be positioned at the space of a pair of external seal, namely be positioned at one and pack.

2. the integrated infusion container be communicated with by puncture according to claim 1, is characterized in that, isolation barrier is one can be run through and be sealed by perforator the elastomer (3a) of being made by rubber or other materials of perforator outer wall.

3. the integrated infusion container be communicated with by puncture according to claim 1, it is characterized in that, the funtion part for connecting of the upper related intrinsic parts of medical liquid container (1), medicinal liquid carrier (2) is connected as a single entity medical liquid container (1) and medicinal liquid carrier (2), and the part that may contact medicinal liquid in the puncture face (3-1) that makes at least isolation barrier and the puncture handshaking procedures of perforator (2a) and medicinal liquid course of conveying is co-located in the sterilized space of a pair of external seal.

4. the integrated infusion container be communicated with by puncture according to claim 1, it is characterized in that, independently for connect and or the parts of sealing and the relevant portion on medical liquid container (1) and medicinal liquid carrier (2) be tightly connected, medical liquid container (1) and medicinal liquid carrier (2) are connected as a single entity.

5. the integrated infusion container be communicated with by puncture according to claim 1, it is characterized in that, packing (4d) is tightly connected with the relevant portion on medical liquid container (1) and medicinal liquid carrier (2), medical liquid container (1) and medicinal liquid carrier (2) are connected as a single entity, make the part that may contact medicinal liquid in the puncture handshaking procedures of the puncture face (3-1) that makes at least isolation barrier and perforator (2a) and medicinal liquid course of conveying be co-located in the sterilized space of a pair of external seal.

6. the integrated infusion container be communicated with by puncture according to claim 1, it is characterized in that, perforator also comprises connecting portion, for the fixing of perforator and with being connected of medicinal liquid transfer pipeline, also can be used for gripping, guiding, spacing, not easily separated, be easy to separation etc. and control perforator.

7. the integrated infusion container be communicated with by puncture according to claim 1, is characterized in that, the part that perforator (2a) may contact with medicinal liquid (0) is positioned at an external airtight space, exists freely.

8. the integrated infusion container be communicated with by puncture according to claim 1, it is characterized in that, the part that perforator (2a) may contact with medicinal liquid (0) is positioned at an external airtight space, partly with the miscellaneous part in the He Huogai space, medial wall of the diaphragm that forms this space, is connected.

9. the integrated infusion container be communicated with by puncture according to claim 1, is characterized in that, the part that perforator (2a) may contact medicinal liquid is positioned at one and participates in by the transition link sterilized space to external seal formed.

10. the integrated infusion container be communicated with by puncture according to claim 1, it is characterized in that, perforator (2a) is connected with the rapid wear formula that is connected to of transition link, to the direction away from medicinal liquid spatial accommodation (1c) firmly, perforator (2a) can break away from the transition link, and the perforator that is connected with medicinal liquid carrier (2) pipeline can be connected by puncture with other medical liquid containers again.

11. according to the described integrated infusion container by puncturing and being communicated with of claim 1-7, it is characterized in that, be provided with and limit perforator (2a) activity in case use the unexpected structure that punctures or puncture elsewhere in front storage and transportation process.

12. the integrated infusion container be communicated with by puncture according to claim 1, is characterized in that, medicinal liquid spatial accommodation (1c) can form multicell through weak soldering, holds respectively variety classes or different shape medicine.

13. according to the integrated infusion container be communicated with by puncture claimed in claim 1, it is characterized in that, medicinal liquid transfer pipeline container end be connected with have at least an inner passage to outer connection component, for with the medicine liquid outlet of other self-existent medical liquid containers, partly being connected, corresponding with the medicine liquid outlet part of self-existent medical liquid container to the shape of outer connection component.

14. according to the integrated infusion container be communicated with by puncture claimed in claim 1, it is characterized in that, what top was sharp is positioned at the inner space of a junction spare to outer connection component.

15. the integrated infusion container be communicated with by puncture according to claim 1 is characterized in that medicinal liquid transfer pipeline container terminal is positioned at one and packs.

16. the integrated infusion container be communicated with by puncture according to claim 1 is characterized in that pipeline all is positioned at one and packs.

17. the integrated infusion container be communicated with by puncture according to claim 1 is characterized in that medical liquid container (1) is deposited for folded with medicinal liquid carrier (2), doubling partly is provided with position limiting structure for soft structure, doubling portion of external.

Images