CN203212513U - Improved synthetic peptide reactor - Google Patents
Improved synthetic peptide reactor Download PDFInfo
- Publication number
- CN203212513U CN203212513U CN 201320198179 CN201320198179U CN203212513U CN 203212513 U CN203212513 U CN 203212513U CN 201320198179 CN201320198179 CN 201320198179 CN 201320198179 U CN201320198179 U CN 201320198179U CN 203212513 U CN203212513 U CN 203212513U
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- CN
- China
- Prior art keywords
- synthetic peptide
- tank body
- upper cover
- modified version
- sealing cover
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- Expired - Lifetime
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Abstract
The utility model relates to an improved synthetic peptide reactor. The improved synthetic peptide reactor comprises an upper sealing cover (1), a lower sealing cover (2) and a tank body (3), wherein a top gas-liquid inlet/outlet and a sampling port (4) are formed in the upper sealing cover (1), and a bottom gas-liquid inlet/outlet is formed in the lower sealing cover; the improved synthetic peptide reactor is characterized in that the upper sealing cover (1) and the lower sealing cover (2) are respectively arranged on the upper end and the lower end of the tank body (3), the junction surfaces of the upper sealing cover (1), the lower sealing cover (2) and the tank body (3) are inclined surfaces, and the upper sealing cover (1), the lower sealing cover (2) and the tank body (3) are combined in a sealing manner through inclined surface lines. Compared with the prior art, the improved synthetic peptide reactor has the advantages of high quality, good benefits, easiness in maintenance, convenience in operation, good sealing property, environment protection, high efficiency and the like.
Description
Technical field
The utility model relates to a kind of reactor, especially relates to a kind of modified version synthetic peptide reactor.
Background technology
The synthetic peptide reactor is the container that carries out building-up reactions during solid-phase polypeptide synthesizes, at present, there is defective in many reactors aspect structure and material, cause fluid turnover instability, difficult, the easy leakage of cleanliness of operation, fragile, have problems such as dead angle, not only in production operation, there are inconvenience and potential safety hazard, and influence quality product.
Summary of the invention
The purpose of this utility model is exactly that a kind of assurance building-up reactions safety, efficient, low consumption, free of contamination modified version synthetic peptide reactor are provided in order to overcome the defective that above-mentioned prior art exists.
The purpose of this utility model can be achieved through the following technical solutions: a kind of modified version synthetic peptide reactor, this reactor comprises upper cover, following capping and tank body, described upper cover is provided with the top gas-liquid and imports and exports and thief hole, described lower seal covers and is provided with bottom gas-liquid import and export, it is characterized in that, described upper cover and following capping are separately positioned on tank body two ends up and down, the bonding surface of upper cover, following capping and tank body is the inclined-plane, and upper cover, following capping and tank body are by inclined-plane linear sealing combination.
Described bonding surface is the inclined-plane with 30～60 degree angles.
Described bonding surface is the inclined-plane with miter angle degree.
The thief hole that arranges on the described upper cover adopts bar-shaped sealing plug sealing, and this bar-shaped sealing plug inserts in the thief hole, and its bottom flushes with the upper cover bottom.Can remove dead angle, thief hole space fully by precision sizing.
The material of described tank body is transparent polypropylene material (PP), and the one side is provided with sightingpiston, but Real Time Observation reaction liquid level situation, and tank wall is provided with chuck.
Described lower seal covers and is provided with filtering system, and this filtering system is made up of the round-hole punched plate on support, the support and the filter screen on the round-hole punched plate.
Described upper cover and following capping are fixed on the tank body by standing bolt.
Fluid enters from the top gas-liquid on the upper cover during work of the utility model reactor, carry out building-up reactions with peptide resin in the tank body, reactor is rotated stirring, import and export pressurization by the top gas-liquid on the upper cover after finishing, waste liquid is imported and exported from the bottom gas-liquid that lower seal covers and is discharged, so repeatedly circulation is synthetic, and sampling analysis is carried out by thief hole in the centre.
Compared with prior art, the present invention has the following advantages:
1. reactionless dead angle, bar-shaped plug and inclined-plane toe-in close the appearance of having avoided the dead angle.
2. good seal performance, reactor three parts are not easy to take place situations such as leakage by inclined-plane linear sealing combination.
3. the fluid turnover is smooth and easy stable, and the sieve plate support makes filtering surface smooth, and stressed even and difficult the obstruction filtered and the feed liquor resistance reduces, and filter screen is cracky not.
4. but Real Time Observation, the transparency of tank body material can guarantee normally to observe liquid level, understands the inside reactor situation.
5. the improvement parts use, change conveniently, and cost is lower.
6. safe and reliable, residue spills in the hole when avoiding taking a sample, reaction solution is revealed, the turnover of retort internal cause has some setbacks causes the damaged generation that causes abnormal conditions such as resin carrier loss of less or the more and filter screen of fluid.
Description of drawings
Fig. 1 is a kind of modified version synthetic peptide of the utility model reactor synoptic diagram.
Fig. 2 is the bar-shaped sealing plug synoptic diagram of the utility model.
Fig. 3 is the utility model filter holder vertical view.
Fig. 4 is the utility model filter holder side-view.
Embodiment
Below in conjunction with the drawings and specific embodiments the utility model is elaborated.
Embodiment 1
Shown in Fig. 1～4; modified version synthetic peptide reactor comprises upper cover 1; following capping 2 and tank body 3; described upper cover 1 is provided with the top gas-liquid and imports and exports and thief hole 4; described capping 2 down is provided with the bottom gas-liquid and imports and exports; described upper cover 1 and following capping 2 are separately positioned on tank body, and about in the of 3 two ends; upper cover 1; the bonding surface of following capping 2 and tank body 3 is the inclined-plane; upper cover 1; following capping 2 and tank body 3 are by inclined-plane linear sealing combination; wherein upper cover 1; following capping 2 bevel angles are 40 degree; tank body about in the of 3 bevel angle be 45 the degree; upper cover 1 and following capping 2 are fixed on the tank body 1 by standing bolt 8; make three part ramp structures reach excellent sealing effect in the mode of linear sealing by regulating standing bolt 8; upper cover thief hole 4 uses bar-shaped sealing plug 6; this bar-shaped sealing plug 6 inserts in the thief hole; its bottom flushes with upper cover 1 bottom; thief hole 4 reaction dead angles have been eliminated fully; the material of described tank body 1 is transparent polypropylene material (PP); the one side is provided with sightingpiston 10; but Real Time Observation reaction liquid level situation; can observe reactor liquid level situation in the reaction; tank body 1 wall is provided with chuck 11; following capping 2 is provided with filtering system; this filtering system is made up of the filter screen on filter holder 7 and the filter holder; described filter holder is by support; round-hole punched plate on the support is formed; the filter holder 7 of following capping 2 can support reactant and weight resin; the protection filter screen; the resin loses of avoiding accident to cause can reduce again to filter and fluid turnover resistance, and production efficiency is improved.
Embodiment 2
The bonding surface of upper cover, following capping and tank body is the inclined-plane, and wherein upper cover, following capping bevel angle are 30 degree, and tank body bevel angle up and down is 35 degree.All the other are with embodiment 1.
Embodiment 3
The bonding surface of upper cover, following capping and tank body is the inclined-plane, and wherein upper cover, following capping bevel angle are 55 degree, and tank body bevel angle up and down is 60 degree.All the other are with embodiment 1.
Claims (7)
1. modified version synthetic peptide reactor, this reactor comprises upper cover (1), following capping (2) and tank body (3), described upper cover (1) is provided with the top gas-liquid and imports and exports and thief hole (4), described lower seal covers and is provided with bottom gas-liquid import and export, it is characterized in that, described upper cover (1) and following capping (2) are separately positioned on tank body (3) two ends up and down, the bonding surface of upper cover (1), following capping (2) and tank body (3) is the inclined-plane, and upper cover (1), following capping (2) and tank body (3) are by inclined-plane linear sealing combination.
2. modified version synthetic peptide reactor according to claim 1 is characterized in that, described bonding surface is the inclined-plane with 30～60 degree angles.
3. modified version synthetic peptide reactor according to claim 1 and 2 is characterized in that, described bonding surface is the inclined-plane with miter angle degree.
4. modified version synthetic peptide reactor according to claim 1, it is characterized in that, the thief hole that arranges on the described upper cover (4) adopts bar-shaped sealing plug (6) sealing, and this bar-shaped sealing plug (6) inserts in the thief hole (4), and its bottom flushes with upper cover (1) bottom.
5. modified version synthetic peptide reactor according to claim 1 is characterized in that, the material of described tank body (1) is the transparent polypropylene material, and the one side is provided with sightingpiston (10), and tank wall is provided with chuck (11).
6. modified version synthetic peptide reactor according to claim 1 is characterized in that, described capping (2) down is provided with filtering system, and this filtering system is made up of the round-hole punched plate on support (7), the support and the filter screen on the round-hole punched plate (9).
7. modified version synthetic peptide reactor according to claim 1 is characterized in that, described upper cover (1) and following capping (2) are fixed on the tank body (3) by standing bolt.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320198179 CN203212513U (en) | 2013-04-18 | 2013-04-18 | Improved synthetic peptide reactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320198179 CN203212513U (en) | 2013-04-18 | 2013-04-18 | Improved synthetic peptide reactor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203212513U true CN203212513U (en) | 2013-09-25 |
Family
ID=49202064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320198179 Expired - Lifetime CN203212513U (en) | 2013-04-18 | 2013-04-18 | Improved synthetic peptide reactor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203212513U (en) |
-
2013
- 2013-04-18 CN CN 201320198179 patent/CN203212513U/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 200241 Jiangchuan East Road, Shanghai, No. 48, No. Patentee after: SHANGHAI SHEN LIAN BIOMEDICAL Corp. Address before: 200241 Jiangchuan East Road, Shanghai, No. 48, No. Patentee before: SHEN LIAN BIOTECHNOLOGY Co.,Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20130925 |
|
| CX01 | Expiry of patent term |