CN203153996U - Experiment animal steam scalding device - Google Patents

Experiment animal steam scalding device Download PDF

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Publication number
CN203153996U
CN203153996U CN 201320130485 CN201320130485U CN203153996U CN 203153996 U CN203153996 U CN 203153996U CN 201320130485 CN201320130485 CN 201320130485 CN 201320130485 U CN201320130485 U CN 201320130485U CN 203153996 U CN203153996 U CN 203153996U
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China
Prior art keywords
steam
mould
scalding
scalded
hollow
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Expired - Fee Related
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CN 201320130485
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Chinese (zh)
Inventor
胡大海
白晓智
陶克
汤朝武
朱雄翔
韩军涛
董茂龙
石继红
贾文斌
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Priority to CN 201320130485 priority Critical patent/CN203153996U/en
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Abstract

The utility model relates to an experiment animal steam scalding device. The experiment animal steam scalding device at least comprises a steam generation system, a steam duct, a steam sprayer and a scalding mold, and is characterized in that the inlet end of the steam generation system is fixedly connected with a water box, the outlet end of the steam generation system is fixedly connected with one end of the steam duct, the other end of the steam duct is the steam sprayer, and the steam sprayer can be connected in the scalding mold in a sleeved mode. The experiment animal steam scalding device has the advantages of being simple in molding, stable in model, high in repeatability, controllable in area and scalding depth and the like, and can provide good experiment animal models for the research on the human scalding pathology and the molecular mechanism, screening of scalding treatment drugs and efficacy evaluation.

Description

A kind of laboratory animal steam is scalded device
Technical field
This utility model relates to medical treatment test instrument field, and particularly a kind of laboratory animal steam is scalded device.
Background technology
Burn system is by the tissue injury due to heating power, electric current, chemical substance, the lonizing radiation etc.Usually said burn refers to that namely the hydrothermal solution that caused by heating power scalds, and traumatogenic reason comprises the liquid that boils (water, soup, oil), steam, high-temperature gas, flame, red-hot metal (liquid or solid) etc.Burn is mainly in daily life, production and construction activity, natural disaster, war.According to regional epidemiology statistics, the average year sickness rate of burn is the 0.5%-1% of total population, and according to the traumatogenic reason classification, 85%-90% is heat injury among the fire victim.Therefore the structure of good heat injury model is great to the burn Research Significance, helps science more, the rule of development of understanding burn back each system of body and wound healing more accurately, explores more effective treatment means.
Summary of the invention
The purpose of this utility model provides a kind of laboratory animal steam and scalds device, and it is simple that this device has modeling, model stability, characteristics such as repeatability is high, and area, depth of burn are controlled.Can be pathology and the Study on Molecular Mechanism of human burn, be the screening of burn treatment medicine, and evaluating drug effect provides good experimental animal model.
The technical scheme that its technical problem that solves this utility model adopts is: a kind of laboratory animal steam is scalded device, which comprises at least steam generating system, steam lead, steam jet and scald mould, it is characterized in that: the entrance point of steam generating system is fixedlyed connected with water tank, the port of export of steam generating system is fixedlyed connected with steam lead one end, the other end of steam lead is steam jet, and steam jet can be socketed in scalds in the mould.
There is the inner core heating element described steam generating system inside, and the inner core heating element is by being electrically connected with outside 220V alternating current power supply.
There is hand-held device the position that described steam lead closes on steam jet.
Described scald mould is hollow column mould or hollow side's mould.
Described hollow column mould is the hollow cylindrical structure, and hollow side's mould is hollow cuboid column structure, and hollow column mould and hollow side's mould all are that upper port is docked with steam jet, and lower port is close to the animal skin that needs are scalded.
The beneficial effects of the utility model are by water tank steam generating system to be added water, the inner core heating element makes normal-temperature water be vaporized into high-temperature vapor behind the power-on switch, and the process steam lead is discharged scorching hot steam by steam jet, only need to add one on the pre-scalded skin of animal surface in the use and scald mould, steam jet is aimed at the scald mould and is got final product, scorching hot steam by steam jet ejection is to rat, mice, Cavia porcellus, rabbit, animal such as pig and Canis familiaris L. depilation back skin surface is scalded test, continue the several seconds, can select the scald mould of the different sizes of difformity according to different situations; The recovery of fluid infusion immediately after the wound, sub-cage rearing, free diet; Adopt observation and the classification of definite burn under the wound tissue pathological section light microscopic; This scald device has easy and simple to handle, favorable reproducibility, and the success rate height, the scald degree is easy to advantages such as control, can be used for researchs such as the screening of pathomechanism, medicine of human burn and evaluation.
Description of drawings
Further specify below in conjunction with this utility model of embodiment.
Fig. 1 is this utility model structural representation;
Fig. 2 is that hollow column is scalded the mould structure sketch map;
Fig. 3 is that hollow side's body is scalded the mould structure sketch map;
Among the figure: 1, on and off switch; 2, water tank; 3, steam generating system; 4, steam lead; 5, steam jet; 6, hand-held device; 7, hollow column mould; 8, hollow side's mould.
The specific embodiment
Embodiment 1
Scald shown in the apparatus structure sketch map as this laboratory animal steam of Fig. 1, which comprises at least steam generating system 3, steam lead 4, steam jet 5 and scald mould, the entrance point of steam generating system 3 is fixedlyed connected with water tank 2, the port of export of steam generating system 3 is fixedlyed connected with steam lead 4 one ends, the other end of steam lead 4 is steam jet 5, and steam jet 5 can be socketed in scalds in the mould.
There is the inner core heating element steam generating system 3 inside, and the inner core heating element is electrically connected with outside 220V alternating current power supply by on and off switch 1, by on and off switch 1 its keying of control.
There is hand-held device 6 position that steam lead 4 closes on steam jet 5, and hand-held device 6 can effectively completely cut off the heat of steam lead 4, and use can not burnt with hand.
During use, add water by 2 pairs of steam generating systems 3 of water tank, power-on switch 1 back inner core heating element makes normal-temperature water be vaporized into high-temperature vapor, and process steam lead 4 is discharged scorching hot steam by steam jet 5, only need to add one on the pre-scalded skin of animal surface in the use and scald mould, steam jet 5 is aimed at mould and is got final product, scorching hot steam by steam jet 5 ejection is to rat, mice, Cavia porcellus, rabbit, animal such as pig and Canis familiaris L. depilation back skin surface is scalded test, continue the several seconds, can select the scald mould of the different sizes of difformity according to different situations; The recovery of fluid infusion immediately after the wound, sub-cage rearing, free diet; Adopt observation and the classification of definite burn under the wound tissue pathological section light microscopic; This scald device has easy and simple to handle, favorable reproducibility, and the success rate height, the scald degree is easy to advantages such as control, can be used for researchs such as the screening of pathomechanism, medicine of human burn and evaluation.
Embodiment 2
Scald mould in above-described embodiment is hollow column mould 7 or hollow side's mould 8 or other arbitrary shape, specifically need be according to the different burn surface area of required making, and the laboratory animal disease model of different depth of burns is chosen corresponding scald mould
As shown in Figure 2, hollow column mould 7 is the hollow cylindrical structure, and upper port is docked with steam jet 5, and lower port is aimed at the animal skin that needs scald; As shown in Figure 3, hollow side's mould 8 is hollow cuboid column structure, and upper port is docked with steam jet 5, and lower port is aimed at the animal skin that needs scald.
Adopt healthy male cleaning level BALb/c mice to carry out animal experiment, body weight 20-25g below.Available from The Fourth Military Medical University's Experimental Animal Center, ad lib water inlet, humidity 50%, room temperature maintain 25-28 ℃, 12h daytime, 12h feeding environment at night.
Embodiment 3
Shallow two degree mice scalding models:
Get the BALB/c mice and weigh, 1% pentobarbital sodium intraperitoneal injection of anesthesia.Earlier shave off the back with shaver and become mildewed, the depilation of 10% sodium sulfide forms 15%TBSA and waits to scald the zone.Behind the 24h, suck anesthetized mice with isoflurane.Steam is scalded the device water tank and is added water, opening power preheating 1min, select for use internal diameter 2.0cm hollow column to scald mould, skin of back with the steam jet alignment mark, scald 2s, get the section of mouse skin specimen routine paraffin wax embedding skin histology after reaching 24h after the scald at once, the sick inspection of HE dyeing: the mouse skin necrosis comes off, part skin corium necrocytosis, adnexa tissues such as hair follicle exist for shallow two degree scalding models.
Embodiment 4
Dark two degree mice scalding models:
Get the BALB/c mice and weigh, 1% pentobarbital sodium intraperitoneal injection of anesthesia.Earlier shave off the back with shaver and become mildewed, the depilation of 10% sodium sulfide forms 15%TBSA and waits to scald the zone.Behind the 24h, suck anesthetized mice with isoflurane.Steam is scalded the device water tank and is added water, opening power preheating 1min, select for use internal diameter 2.0cm hollow column to scald mould, with the skin of back of steam jet alignment mark, continue to scald 5s, at once get the section of mouse skin specimen routine paraffin wax embedding skin histology after reaching 24h after the scald, the sick inspection of HE dyeing: the mouse skin pull-up falls, and skin corium is impaired, visible indivedual remaining hair follicle cells, hematoclasis in the visible vessels, ridge layer and fat deposit structure normally are dark two degree scalding models.
Embodiment 5
Three degree mice scalding models:
Get the BALB/c mice and weigh, 1% pentobarbital sodium intraperitoneal injection of anesthesia.Earlier shave off the back with shaver and become mildewed, the depilation of 10% sodium sulfide forms 15%TBSA and waits to scald the zone.Behind the 24h, suck anesthetized mice with isoflurane.Steam is scalded the device water tank and is added water, opening power preheating 1min, select for use internal diameter 2.0cm hollow column to scald mould, with the skin of back of steam jet alignment mark, scald 8s, get the section of mouse skin specimen routine paraffin wax embedding skin histology after reaching 24h after the scald at once, the sick inspection of HE dyeing: the mouse skin pull-up falls, skin corium, ridge layer and fat deposit structural deterioration, it is unclear to demarcate, hinder to Musclar layer be three the degree scalding models.
The parts that present embodiment is not described in detail and structure belong to well-known components and common structure or the conventional means of the industry, here not narration one by one.

Claims (5)

1. a laboratory animal steam is scalded device, which comprises at least steam generating system (3), steam lead (4), steam jet (5) and scald mould, it is characterized in that: the entrance point of steam generating system (3) is fixedlyed connected with water tank (2), the port of export of steam generating system (3) is fixedlyed connected with steam lead (4) one ends, the other end of steam lead (4) is steam jet (5), and steam jet (5) can be socketed in scalds in the mould.
2. a kind of laboratory animal steam according to claim 1 is scalded device, and it is characterized in that: there is the inner core heating element described steam generating system (3) inside, and the inner core heating element is electrically connected with outside 220V alternating current power supply by (1).
3. a kind of laboratory animal steam according to claim 1 is scalded device, and it is characterized in that: there is hand-held device (6) position that described steam lead (4) closes on steam jet (5).
4. a kind of laboratory animal steam according to claim 1 is scalded device, and it is characterized in that: described scald mould is hollow column mould (7) or hollow side's mould (8).
5. a kind of laboratory animal steam according to claim 4 is scalded device, it is characterized in that: described hollow column mould (7) is the hollow cylindrical structure, hollow side's mould (8) is hollow cuboid column structure, hollow column mould (7) and hollow side's mould (8) all are that upper port is docked with steam jet (5), and lower port is close to the animal skin that needs are scalded.
CN 201320130485 2013-03-21 2013-03-21 Experiment animal steam scalding device Expired - Fee Related CN203153996U (en)

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CN 201320130485 CN203153996U (en) 2013-03-21 2013-03-21 Experiment animal steam scalding device

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Application Number Priority Date Filing Date Title
CN 201320130485 CN203153996U (en) 2013-03-21 2013-03-21 Experiment animal steam scalding device

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CN203153996U true CN203153996U (en) 2013-08-28

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565536A (en) * 2013-10-29 2014-02-12 中国人民解放军第四军医大学 Simulation steam nozzle of uniform steam burn model, applicable to different body surface areas
CN109717980A (en) * 2018-12-29 2019-05-07 重庆医药高等专科学校 Burn and scald sprays film medicament experimental provision

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565536A (en) * 2013-10-29 2014-02-12 中国人民解放军第四军医大学 Simulation steam nozzle of uniform steam burn model, applicable to different body surface areas
CN103565536B (en) * 2013-10-29 2015-10-14 中国人民解放军第四军医大学 A kind of simulation vapour lock being applicable to different body surface area uniform steam bum model
CN109717980A (en) * 2018-12-29 2019-05-07 重庆医药高等专科学校 Burn and scald sprays film medicament experimental provision
CN109717980B (en) * 2018-12-29 2020-11-06 重庆医药高等专科学校 Burn and scald film spraying medicament experimental device

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130828

Termination date: 20150321

EXPY Termination of patent right or utility model