CN203112839U - Novel PCR module mechanism - Google Patents
Novel PCR module mechanism Download PDFInfo
- Publication number
- CN203112839U CN203112839U CN 201320080404 CN201320080404U CN203112839U CN 203112839 U CN203112839 U CN 203112839U CN 201320080404 CN201320080404 CN 201320080404 CN 201320080404 U CN201320080404 U CN 201320080404U CN 203112839 U CN203112839 U CN 203112839U
- Authority
- CN
- China
- Prior art keywords
- module
- test tube
- tube hole
- heat conduction
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a novel PCR (Polymerase Chain Reaction) module mechanism. The novel PCR module mechanism comprises a module body, and is provided with a module heat conducting plate in close connection with the module body and a plurality of sensor fixing legs arranged on the module heat conducting plate, wherein a plurality of test tube hole slots are formed in the module body; a plurality of heat conducting pillars corresponding to the test tube hole slots are arranged on the sides, opposite to the opening directions of test tube hole slots, of the bottoms of the test tube hole slots; and the end surfaces of the heat conducting pillars and the plate surfaces of the module heat conducting plates are in press-fit arrangement. According to the module mechanism, as the heat conducting pillars are in contact with the module heat conducting plate, heat is directly transmitted to the test tube hole slots; as the module body and the module heat conducting plate are lighter in weight and have low requirement on the power of heating chips, the temperature increase and reduction speeds of the module mechanism are high, the temperature transmission uniformity is high, and the power requirementis low; and meanwhile, as the heat conducting pillars with unequal diameters are adopted, the edge effect is effectively prevented, and the gene amplification effect and the detection performance accuracy and stability of the whole instrument are greatly improved.
Description
Technical field
The utility model relates to the gene-amplificative instrament technical field, especially relates to novel PC R gene-amplificative instrament module mechanism.
Background technology
Pcr gene amplification instrument be a when simulation gene amplification is provided in required temperature device of each stage, and functions such as increase low-temperature storage and fluoroscopic examination, be applicable to the human genome engineering science, the polymerase chain reaction fluorescent quantitation in clinical diagnosis fields such as research field such as medical jurisprudence, oncology, tissue and Population Biology, petrifactology, zoology, phytology and virus, tumour, inherited disease detects.
Pcr gene amplification instrument work key is temperature control.The homogeneity of temperature is related to the consistence of reaction structure between the different sample wells, and " fringing effect of position " can influence the repeatability of structure.Warming and cooling rate is fast, can increase work efficiency, and improves the PCR atopic.
All pcr gene amplification instrument of existing market, include the host platform that writes each phase temperature sequence of control, carry out power output for the module mechanism that has the heating chip that freezes by host platform again, make the test tube groove surfaces temperature on the module mechanism reach the required temperature of gene amplification, increase being equipped with in the test tube groove that needs in the test tube of the amplifing reagent insert module mechanism, heat by hot cover, guaranteeing that invisible spectro reagent is not evaporated and collects reveals on the test tube wall, again by the exciting and absorb fluorescence data analysis of photoelectric probe, thereby draw the result of various judgements.
The module mechanism of pcr gene amplification instrument is one of key element of pcr gene amplification instrument, has determined the gene amplification effect of pcr gene amplification instrument integral body and has detected performance precision and stability.The pcr gene amplification instrument of existing market, its module mechanism all adopts integral material precision work or casting to form, the lower phenomenon of fringing effect, homogeneity and warming and cooling rate that all has module mechanism, performance, production cost and the physical size of the present like product of serious restriction are a greater impact the development of whole industry.
Chinese patent literature (the day for announcing: on November 14th, 2012, notification number: CN202530086U) disclose a kind of module mechanism of PCR-based gene-amplificative instrament, comprise the module upper body, with the airtight module base that is connected in module upper body, sensor and heating and cooling chip, evenly be provided with several test tube hole slots on the described module upper body, a side opposite with the opening direction of test tube hole slot on the module upper body constitutes some grooves, described module upper body and module base constitute a whole airtight cavity, be filled with the superconduct heat media that contains a large amount of heat conduction ions in the described airtight cavity, described heating and cooling chip is fixedlyed connected with module base, and described sensor is arranged between module base and the heating and cooling chip.
Technique scheme adopts the superconduct heat media that contains a large amount of heat conduction ions, solves temperature equalisation, improves warming and cooling rate, and then improves the gene amplification effect of instrument integral body and precision and the stability of detection performance.Also there is certain limitation in technique scheme, because the superconduct heat media of heat conduction ion has the limitation of himself.
Chinese patent literature (the day for announcing: on July 30th, 1997, notification number: CN2258618Y) disclose a kind of sample cell of multi-functional pcr gene amplification instrument.This sample cell is divided into left and right two districts, and wherein left side district frid is provided with the blind hole of placing test tube, in order to carry out test tube PCR; Right district frid is provided with the platform of placing slide glass, is used for carrying out original position PCR, molecular hybridization in situ and immunohistochemical test.The frid hot spots is the electrical heating element that inserts the frid body from the side; Cooling segment is the water-cooling groove that is positioned at the frid bottom surface.
Above-mentioned technology is in order to solve the sample cell function singleness, the problem that warming and cooling rate is slow, and do not relate to for the problem of pcr gene amplification instrument fringing effect and temperature rise rate deficiency.
Chinese patent literature (the day for announcing: on May 11st, 2011, notification number: CN201825953U) disclose a kind of alternating temperature metal module with the precision temperature compensation, described alternating temperature metal module is provided with sample well, comprise temperature compensation heater, described temperature compensation heater the quantity that arranges that quantity is less than or equal to described sample well is set, described temperature compensation heater is connected with pilot circuit, and described each temperature compensation heater is arranged on around the sample well separately.
Technique scheme is in order to solve the problem to the sample well temperature compensation, though this scheme can realize the temperature of sample well is compensated this complex structure, cost height.
The utility model content
The purpose of this utility model is to provide a kind of for the problem that solves the common fringing effect that exists of the amplification of pcr gene in prior art instrument module mechanism and temperature rise rate deficiency can make the pcr gene amplification instrument module mechanism that surface temperature reaches balanced and hypervelocity heats up.
The utility model realizes that the technical scheme that its technical purpose adopts is: novel PC R gene-amplificative instrament module mechanism, comprise module body, also be provided with the module body equal plate of close-connected module heat conduction and be arranged on a plurality of sensor fixed legs on the equal plate of module heat conduction, described module body is provided with some test tube hole slots, the bottom of a test tube hole slot side opposite with test tube hole slot opening direction is provided with several corresponding to the heating column of test tube hole slot, and the end face of described heating column rides over the plate face of the equal plate of module heat conduction.This module mechanism, by at the heating column of the opposite side setting of test tube hole slot opening direction corresponding to the test tube hole slot, this heating column rides over the equal plate of module heat conduction, such structure makes the heat on the equal plate of module heat conduction can be directly passed to heating column, and heating column and test tube hole slot are integrative-structures, overcome the common fringing effect that exists of present pcr gene amplification instrument module mechanism fully, make the temperature of each test tube hole slot on the module reach balanced, the temperature difference is all controlled within 0.05 ℃ to 0.1 ℃ scope, warming and cooling rate reaches the unprecedented speed more than 10 ℃/second, so just greatly reduce the power requirement to the heating and cooling chip, reduce the output rating of equipment, reduced the cost of equipment.Simultaneously, because the quality of module body and the equal plate of module heat conduction is less, do not need heat-conducting medium, be conducive to temperature homogeneity control, heat transfer efficiencies is higher than the heat transfer efficiency that adopts heat-conducting medium or regular-PCR gene-amplificative instrament module mechanism far away, can rapidly the heat of pyrotoxin be conducted to equably the test tube hole slot surface of module body, because the setting of this structure, make the warming and cooling rate of this series products considerably beyond 5.5 ℃/second of present like products, warming and cooling rate can reach more than 10 ℃/second, satisfies the rapid amplifying demand of range gene greatly.
As preferably, described heating column is cylindrical structure, away from the diameter of the heating column of the pyrotoxin that is arranged on the equal plate of the module heat conduction below heating column diameter greater than the pyrotoxin center.The diameter of heating column does not wait, away from the heating column diameter of the pyrotoxin heating column diameter greater than the pyrotoxin center, such structure is in order to solve fringing effect, improve heat passage homogeneity and improve warming and cooling rate, because the end face of heating column rides over the equal plate of module heat conduction, contact area is more big, the heat that transmits is more high, at different test objectives, heating column diameter in this pcr gene amplification instrument module mechanism can be done different designs, and also can be according to the position that arranges of pyrotoxin for the heating column on the same module body, the heating column diameter greater than the pyrotoxin center that will arrange away from the heating column diameter of pyrotoxin, with the design of the diameter of edge greater than the center, perhaps the ecto-entad structure that tapers off arranges the diameter of heating column.
As preferably, described test tube hole slot is matrix structure and is distributed on the module body.Test tube hole slot on the module body can arrange as required and be matrix structure, and also is matrix structure corresponding to the heating column of test tube hole slot, can certainly be other structures, as long as satisfy test objective.
As preferably, be arranged on the diameter of heating column of module body edge greater than the diameter of the heating column that is arranged on the module body middle part.Preferably be arranged on the diameter of heating column of module body edge greater than the diameter of the heating column that is arranged on module body middle part, such structure is generally speaking when pyrotoxin is arranged on module body middle part or pyrotoxin and evenly is laid on the module body, because module body edge rapid heat dissipation, the middle portion heat radiation is slow, such structure can solve fringing effect effectively, while also makes heat passage more even, and warming and cooling rate can be faster.
As preferably, the inside of described sensor fixed leg is provided with the sensor installation cavity, the opening of described sensor installation cavity is towards equal plate one side of module heat conduction, be provided with open holes corresponding to the sensor installation cavity on the equal plate of module heat conduction, described sensor fixed leg and the equal plate of module heat conduction are structure as a whole.The inside of sensor fixed leg is provided with the sensor installation cavity, and it is the setting of sensor for convenience that open holes is set on the equal plate of module heat conduction, and then makes the sensor temperature of test tubes hole slot better, design temperature sequence of control.
As preferably, module body, the equal plate of module heat conduction and sensor fixed leg are respectively the heat conduction members that is made of the material with good heat conductive performance, and described module body, the equal plate of module heat conduction and sensor fixed leg form a complete pcr gene amplification instrument module mechanism.Module body, the equal plate of module heat conduction and the good heat conduction member of the preferred heat conductivility of sensor fixed leg are in order to guarantee rapidly the temperature of pyrotoxin to be conducted to equably the test tube hole slot surface of module body.
As preferably, described module body is provided with on the outside surface of test tube hole slot one side and also is provided with heat insulating mattress, is provided with several circular holes corresponding to the test tube hole slot on the described heat insulating mattress.When module mechanism is worked, in order to reduce ambient temperature to the influence of the surface temperature of module mechanism, therefore, the outside surface that the test tube hole slot is set in module body wraps up the heat insulating mattress that one deck has good effect of heat insulation, like this, the temperature of module mechanism and the temperature of setting program more are tending towards controlling more accurate synchronously.
As preferably, described heat insulating mattress is the member that is made of the material with good effect of heat insulation.Heat insulating mattress is set to the good member of effect of heat insulation, is the influence that is subjected to external environment for fear of module mechanism.
As preferably, the outside of module body and the equal plate of module heat conduction also is provided with module cage, and described module cage housing is provided with some perforates corresponding to the circular hole on the heat insulating mattress on the described module cage on heat insulating mattress.The purpose that module cage is set is for the equal plate lid of heat insulating mattress, module body and module heat conduction is firm, to reduce ambient temperature to the influence of the surface temperature of module mechanism.
As preferably, described module cage is the cover body that is made of temperature-resistant material.Module cage is set to the heatproof cover body, is to cause the module cage distortion in order to prevent in use owing to the rising of temperature, and influence is used.
The beneficial effects of the utility model are: this module mechanism directly adopts heating column to contact with the equal plate of module heat conduction, heat is directly passed to the test tube hole slot, because module body and the equal plate quality of module heat conduction are less, power requirement to euthermic chip is low, therefore this module mechanism warming and cooling rate is fast, transmission temperature homogeneity height, power requirement is low, the heating column that adopts diameter not wait simultaneously, solved fringing effect effectively, improved the gene amplification effect of instrument integral body and precision and the stability of detection performance greatly, and this module mechanism has been easy to make, assembling is simple, and cost is low.
Description of drawings
Fig. 1 is a kind of constitutional diagram of the utility model module body and the equal plate of module heat conduction;
Fig. 2 is a kind of structural representation of the utility model pcr gene amplification instrument module mechanism;
Fig. 3 is a kind of structural representation of module body in the utility model;
Fig. 4 is the another kind of structural representation of module body in the utility model;
Fig. 5 is a kind of application structure synoptic diagram of the present utility model;
Among the figure: 1, module body, 2, the equal plate of module heat conduction, 3, the sensor fixed leg, 4, test tube hole slot, 5, heating column, 6, the sensor installation cavity, 7, open holes, 8, heat insulating mattress, 9, module cage, 10, press box, 11, heating and cooling chip, 12, scatterer, 13, circuit card, 14, sensor, 15, test tube.
Embodiment
Also by reference to the accompanying drawings the technical solution of the utility model is described in further detail below by specific embodiment.
Embodiment 1:
In the embodiment shown in fig. 1, novel PC R gene-amplificative instrament module mechanism, the module body 1 that comprises rectangle structure, with the module body equal plate 2 of 1 close-connected module heat conduction and be arranged on a plurality of sensor fixed legs 3 on the equal plate 2 of module heat conduction, module body 1 is provided with some test tube hole slots 4, the module body 1 of general requirements is provided with 96 test tube hole slots 4,96 test tube hole slots 4 are matrix structure and are distributed on the module body 1, the bottom of test tube hole slot 4 side opposite with test tube hole slot 4 opening directions is provided with several corresponding to the heating column 5 of test tube hole slot 4, and heating column 5 is that cylindrical structure and test tube hole slot 4 are one-body molded.The end face of heating column 5 rides over the plate face of the equal plate 2 of module heat conduction.Away from the diameter of the heating column 5 of the pyrotoxin that is arranged on the equal plate of module heat conduction 2 belows heating column 5 diameters greater than the pyrotoxin center.Among this embodiment, adopt four heating and cooling chips 11 as pyrotoxin, pyrotoxin is square and is arranged on the lower surface of the equal plate 2 of module heat conduction, therefore, distributed architecture corresponding to above-mentioned pyrotoxin, heating column 5 on the module body 1 is set to four groups corresponding to pyrotoxin, and all less than the heating column 5 diameter (see figure 3)s away from pyrotoxin, the heating column 5 on the whole like this module body 1 also just is four component cloth at the center of the heating column 5 of each pyrotoxin center position.
The inside of sensor fixed leg 3 is provided with sensor installation cavity 6, the opening of sensor installation cavity 6 is towards equal plate 2 one sides of module heat conduction, be provided with open holes 7 corresponding to sensor installation cavity 6 on the equal plate 2 of module heat conduction, sensor fixed leg 3 constitutes integrative-structure with the equal plate 2 of module heat conduction.Module body 1, the equal plate 2 of module heat conduction and sensor fixed leg 3 are respectively the heat conduction members that is made of materials such as the copper with good heat conductive performance, aluminium, silver, and module body 1, the equal plate 2 of module heat conduction and sensor fixed leg 3 form the module mechanism of a complete pcr gene amplification instrument.
Embodiment 2:
In the embodiment shown in fig. 4, pcr gene amplification instrument module mechanism is substantially the same manner as Example 1, difference is: the setting that the diameter of heating column 5 does not wait, in the present embodiment, pyrotoxin divides four belows that are arranged on module body 1, is arranged on the diameter of heating column 5 of whole module body 1 edge greater than the diameter of the heating column 1 that is arranged on module body 1 middle part.Such structure setting is to consider that the heat radiation at module body 1 edge is than the rapid heat dissipation at module body 1 middle part, heating column 5 diameters greater than the portion in the module body 1 that the diameter of the heating column 5 of module body 1 edge is arranged, be conducive to solve fringing effect, improve temperature homogeneity and warming and cooling rate.
As shown in Figure 5, this pcr gene amplification instrument module mechanism that is formed by module body 1, the equal plate 2 of module heat conduction and sensor fixed leg 3 also is provided with heat insulating mattress 8 at the outside surface of module body 1, and heat insulating mattress 8 is to adopt the heat insulation foam with good effect of heat insulation.Heat insulating mattress 8 is provided with a plurality of circular holes, the test tube hole slot 4 corresponding settings on circular hole and the module body 1.The outside of module body 1 and the equal plate 2 of module heat conduction also is provided with module cage 9, module cage 9 is the cover bodies that are made of high temperature resistant PBT or other high temperature material, module cage 9 housings on heat insulating mattress 8, on the module cage 9 with heat insulating mattress 8 on the circular hole corresponding section be provided with some perforates.During application, by a press box 10 module cage 9 is fastened, press box 10 is fixed on module mechanism and heating and cooling chip 11 on the gene-amplificative instrament scatterer 12, fixes the circuit card 13 of control heating and cooling chip 11 on the press box 10 again.Because module body 1, the equal plate 2 of module heat conduction and sensor fixed leg 3 form one by the complete processing fixed Combination together, therefore the equal plate 2 of module heat conduction firmly is fixed on the heating and cooling chip 11 of its below on the scatterer 12 of gene-amplificative instrament, heat insulating mattress 8 between module cage 9 and the module body 1 avoids module body 1 to be subjected to the influence of ambient temperature, temperature by sensor 14 real-time monitoring modular bodies 1, signal is fed back to pcr gene amplification instrument main frame by circuit card 13, controlled the working condition of heating and cooling chip 11 again by main frame, thereby the temperature of control module body 1 guarantees to be arranged on the temperature requirements of the amplification gene test tube in the test tube hole slot 4.
When pcr gene amplification instrument host work, at first detect the signal of the sensor 14 on the module mechanism by circuit card 13, judge the temperature of current module mechanism pilot scale tube hole groove 4, the temperature control program of setting according to required amplification gene again, the input signal of power being provided for heating and cooling chip 11 in the module mechanism comes the temperature of control module mechanism pilot scale tube hole groove 4 like this.The contact area size of heating column 5 and the equal plate 2 of module heat conduction by test tube hole slot 4 reverse side on the module body 1, temperature in the whole cavity is tended to balance, solve common fringing effect, temperature homogeneity and the warming and cooling rate problem that exists of existing market upper module fully.
The course of processing of the utility model pcr gene amplification instrument module mechanism is: be example with embodiment 1, adopt the preferable copper of heat conductivility, be made by complete processing and have the module body of a plurality of test tube hole slots 4 and heating column 5, use the preferable copper of heat conductivility again, by the complete processing equal plate 2 of module heat conduction that is made, be processed into sensor fixed leg 3 with the preferable copper of heat conductivility again, and pass through professional technology with module body 1, the equal plate 2 of module heat conduction and sensor fixed leg 3 are combined into one, and make the open holes 7 of sensor installation cavity 6 on the equal plate 2 of module heat conduction on the sensor fixed leg 3, equal plate 2 lower surfaces of module heat conduction of pcr gene amplification instrument module mechanism are close to pyrotoxin heating and cooling chip 11, so just can above the pyrotoxin heating and cooling chip 11 by module heat conduction on equal plate 2 and the module body size of the contact area of heating column 5 control the temperature of test tube hole slot 4, make module test tube hole slot 4 internal temperatures reach even distribution, overcome the common fringing effect that exists of present pcr gene amplification instrument module mechanism fully, make each test tube hole slot 4 surface temperature of module body reach balanced, each test tube hole slot 4 surface temperature temperature difference is controlled between 0.05 ℃ to 0.1 ℃.Because the quality of module body 1, heating column 5 and test tube hole slot 4 is less, and can rapidly the heat of pyrotoxin be conducted to equably the surface of test tube hole slot 4 on the module body 1 by heating column 5, warming and cooling rate can reach 10 ℃/second far away, considerably beyond 5.5 ℃/second of present like products, satisfied the rapid amplifying demand of range gene greatly.Simultaneously, because sensor fixed leg 3 quality of module body 1 and the equal plate 2 of module heat conduction and inside are less, greatly reduce the heating power requirement to heating and cooling chip 11, so just reduce the output rating of equipment, greatly reduce the cost of equipment, the profile of equipment also can narrow down to exquisite perfect condition simultaneously.
Above-described embodiment is not restriction to the explanation of technical solutions of the utility model just, and any being equal to that the art those of ordinary skill can be expected substitutes all within the protection domain of the utility model type.
Claims (10)
1. novel PC R gene-amplificative instrament module mechanism, comprise module body, it is characterized in that: also be provided with module body (1) the equal plate of close-connected module heat conduction (2) and be arranged on a plurality of sensor fixed legs (3) on the equal plate of module heat conduction (2), described module body (1) is provided with some test tube hole slots (4), the bottom of test tube hole slot (a 4) side opposite with test tube hole slot (4) opening direction is provided with several heating columns corresponding to test tube hole slot (4) (5), and the end face of described heating column (5) rides over the plate face of the equal plate of module heat conduction (2).
2. novel PC R gene-amplificative instrament module mechanism according to claim 1, it is characterized in that: described heating column (5) is cylindrical structure, away from the diameter of the heating column (5) of the pyrotoxin that is arranged on the equal plate of module heat conduction (2) below heating column (5) diameter greater than the pyrotoxin center.
3. novel PC R gene-amplificative instrament module mechanism according to claim 1, it is characterized in that: described test tube hole slot (4) is matrix structure and is distributed on the module body (1).
4. according to claim 1 or 2 or 3 described novel PC R gene-amplificative instrament module mechanisms, it is characterized in that: be arranged on the diameter of heating column (5) of module body (1) edge greater than the diameter of the heating column (1) that is arranged on module body (1) middle part.
5. novel PC R gene-amplificative instrament module mechanism according to claim 1, it is characterized in that: the inside of described sensor fixed leg (3) is provided with sensor installation cavity (6), the opening of described sensor installation cavity (6) is towards equal plate (2) one sides of module heat conduction, the equal plate of module heat conduction (2) is gone up and is provided with open holes (7) corresponding to sensor installation cavity (6), and described sensor fixed leg (3) is structure as a whole with the equal plate of module heat conduction (2).
6. according to claim 1 or 2 or 3 or 5 described novel PC R gene-amplificative instrament module mechanisms, it is characterized in that: module body (1), the equal plate of module heat conduction (2) and sensor fixed leg (3) are respectively the heat conduction members that is made of the material with good heat conductive performance, and described module body (1), the equal plate of module heat conduction (2) and sensor fixed leg (3) form the module mechanism of a complete pcr gene amplification instrument.
7. according to claim 1 or 2 or 3 or 5 described novel PC R gene-amplificative instrament module mechanisms, it is characterized in that: module body (1) is provided with on the outside surface of test tube hole slot (4) one sides and also is provided with heat insulating mattress (8), and described heat insulating mattress (8) is gone up and is provided with several circular holes corresponding to test tube hole slot (4).
8. novel PC R gene-amplificative instrament module mechanism according to claim 7, it is characterized in that: described heat insulating mattress (8) is the member that is made of the material with good effect of heat insulation.
9. novel PC R gene-amplificative instrament module mechanism according to claim 7, it is characterized in that: the outside of module body (1) and the equal plate of module heat conduction (2) also is provided with module cage (9), described module cage (9) housing is on heat insulating mattress (8), and described module cage (9) is gone up and is provided with some perforates corresponding to the circular hole on the heat insulating mattress (8).
10. novel PC R gene-amplificative instrament module mechanism according to claim 9, it is characterized in that: described module cage (9) is the cover body that is made of temperature-resistant material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320080404 CN203112839U (en) | 2013-02-22 | 2013-02-22 | Novel PCR module mechanism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320080404 CN203112839U (en) | 2013-02-22 | 2013-02-22 | Novel PCR module mechanism |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203112839U true CN203112839U (en) | 2013-08-07 |
Family
ID=48893207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320080404 Expired - Fee Related CN203112839U (en) | 2013-02-22 | 2013-02-22 | Novel PCR module mechanism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203112839U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114669341A (en) * | 2020-12-24 | 2022-06-28 | 厦门致善生物科技股份有限公司 | Reaction device and medical equipment |
-
2013
- 2013-02-22 CN CN 201320080404 patent/CN203112839U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114669341A (en) * | 2020-12-24 | 2022-06-28 | 厦门致善生物科技股份有限公司 | Reaction device and medical equipment |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102046291B (en) | Thermal control system and method for chemical and biochemical reactions | |
| CN103003448B (en) | Improved thermal uniformity for thermal cycler instrumentation using dynamic control | |
| CN113275057B (en) | Thermal control device and method of use thereof | |
| US20140208772A1 (en) | Cooling/heating device | |
| JP2017511697A (en) | Apparatus, system, and method for providing an expandable thermal cycler and isolating a thermoelectric device | |
| CN206232730U (en) | The module thermal balance device of PCR gene amplification instrument | |
| US20190153379A1 (en) | Cell culture incubator and method for operating same | |
| CN111013688B (en) | qPCR module and modularized qPCR device | |
| CN103323488A (en) | Strengthened boiling heat transfer testing device and testing method | |
| CN105813754A (en) | Apparatuses, systems and methods for providing thermocycler thermal uniformity | |
| CN101107507A (en) | Temperature controller for small fluid samples having different heat capacities | |
| EP3126052B1 (en) | Biochemical reaction system | |
| CN105579835A (en) | Sample holder adapted to parallel sample isothermal calorimetry | |
| CN210974696U (en) | Double-temperature-zone PCR amplification device | |
| CN203112839U (en) | Novel PCR module mechanism | |
| CN103160426B (en) | Module mechanism of novel polymerase chain reaction (PCR) gene amplification meter | |
| CN202530086U (en) | Modular mechanism based on PCR (polymerase chain reaction) gene amplification instrument | |
| CN207002685U (en) | PCR gene amplification instrument module thermal balance mechanism | |
| CN105116008A (en) | System component based on accomplishing measurement of heat conductivity coefficients of to-be-test samples with different thicknesses | |
| CN109097455B (en) | Polymerase chain reaction system | |
| CN204882430U (en) | Bad conductor coefficient of heat conductivity measuring device | |
| CN203018101U (en) | Building block type constant-temperature metal bath module | |
| CN103282496B (en) | Method for setting temperature of polymerase chain reaction and instrument thereof | |
| CN205449641U (en) | Metal bath optics temperature measuring device | |
| CN114235196A (en) | Temperature detection device and method in LAMP amplification |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130807 Termination date: 20150222 |
|
| EXPY | Termination of patent right or utility model |